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</ul> </nav> </div> </div> </div> </aside> </div> <main class="main-content col" id="content" role="main"> <section class="section"> <a id="main-content" tabindex="-1"></a> <div data-drupal-messages-fallback class="hidden"></div><div id="block-custom-base-theme-page-title" class="block block-core block-page-title-block"> <div class="content"> <h1 class="title"><span property="schema:name" class="field field--name-title field--type-string field--label-hidden">NCI Resources for Cancer Immunoprevention Research</span> </h1> </div> </div> <div id="block-custom-base-theme-content" class="block block-system block-system-main-block"> <div class="content"> <article data-history-node-id="2653" about="/resources/nci-resources-cancer-immunoprevention-research" typeof="schema:WebPage" class="node node--type-page node--view-mode-full clearfix"> <header> <span property="schema:name" content="NCI Resources for Cancer Immunoprevention Research" class="rdf-meta hidden"></span> </header> <div class="node__content clearfix"> <div property="schema:text" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><table> <thead> <tr> <th>Program Name (Abbreviation)</th> <th>Resources Available to All Researchers</th> <th>How to Access</th> <th>Program Website</th> </tr> </thead> <tbody> <tr> <td>Early Detection Research Network (EDRN)</td> <td>Reference samples for ovary, pancreas, liver, colon, prostate, and other cancer types</td> <td>For requesting samples, go to: <a href="https://edrn.cancer.gov/data-and-resources/specimen-reference-sets/">https://edrn.cancer.gov/data-and-resources/specimen-reference-sets/</a></td> <td><a href="https://edrn.nci.nih.gov">View Website</a></td> </tr> <tr> <td>Human Tumor Atlas Network (HTAN)</td> <td>Spatial transcriptomic data, IHC data, single cell genomic data, tissue image data, etc.</td> <td>For more information, visit: <a href="https://humantumoratlas.org/">https:// humantumoratlas.org/</a></td> <td><a href="https://humantumoratlas.org">View Website</a></td> </tr> <tr> <td>NIAID Vaccine Adjuvant Compendium (VAC)</td> <td>Adjuvant metadata and adjuvant IP-holder information</td> <td>For more information about VAC: email <a href="mailto:DAITAdjuvantGrp@mail.nih.gov">DAITAdjuvantGrp@mail.nih.gov</a>; Contact adjuvant IP-holder directly for specific adjuvant(s) of interest</td> <td><a href="https://vac.niaid.nih.gov">View Website</a></td> </tr> <tr> <td>NIAID Adjuvant Comparison Programs</td> <td>Information about the comparison programs</td> <td>Contact the Program Officers for the respective programs</td> <td><a href="https://www.niaid.nih.gov/research/adjuvant-comparison">View Website</a></td> </tr> <tr> <td>NIAID Adjuvant Comparison and Characterization (ACC) Program</td> <td>Adjuvant metadata available through VAC; Immunologic data available through ImmPort</td> <td>Visit the <a href="https://www.niaid.nih.gov/research/vaccine-adjuvant-compendium-overview">VAC</a> and <a href="https://www.niaid.nih.gov/research/immport">ImmPort</a> websites</td> <td><a href="https://www.niaid.nih.gov/research/adjuvant-comparison-characterization-acc">View Website</a></td> </tr> <tr> <td>PREVENT Cancer Preclinical Drug Development Program (PREVENT)</td> <td>NCI Contract resources to support: <ul> <li>Preclinical pharmacology and efficacy studies</li> <li>Identification and evaluation of intermediate biomarkers</li> <li>Formulation optimization for enhanced bioavailability and clinical usefulness</li> <li>Analytic method development for investigational agents in bulk form and in biological fluids and tissues</li> <li>PK and PK/PD modeling to optimize dosing regimen</li> <li>Scale-up non-cGMP and cGMP production of an investigational agent</li> <li>Preclinical Investigational New Drug–directed good laboratory practice toxicology studies</li> <li>Regulatory support</li> </ul> </td> <td>PREVENT accepts applications from extramural researchers twice a year Applications and submission instructions can be found on the <a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="47a43a7d-a596-48a5-a0a2-4e5d5e19a38a" href="/major-programs/prevent-cancer-preclinical-drug-development-program-prevent" title="PREVENT Cancer Preclinical Drug Development Program (PREVENT)">PREVENT</a> website.</td> <td> <p><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="47a43a7d-a596-48a5-a0a2-4e5d5e19a38a" href="/major-programs/prevent-cancer-preclinical-drug-development-program-prevent" title="PREVENT Cancer Preclinical Drug Development Program (PREVENT)">View Website</a></p> </td> </tr> <tr> <td>Cancer Prevention Clinical Trials Network (CP-CTNet)</td> <td>Support for clinical trials, including management/oversight, trial conduct, participant care, and primary/secondary endpoint analysis</td> <td>Join CP-CTNet via an LAO. Contact Eva Szabo, MD, Director CP-CTNet: <a href="mailto:szaboe@mail.nih.gov">szaboe@mail.nih.gov</a></td> <td><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="2d18f4ca-1125-422e-8e4b-1b6c98302f85" href="/major-programs/cancer-prevention-clinical-trials-network-cp-ctnet" title="Cancer Prevention Clinical Trials Network (CP-CTNet)">View Website</a></td> </tr> </tbody> </table> <div class="footnote">Abbreviations<br> <br> PD = pharmacodynamics<br> PK = pharmacokinetics<br> LAO = Lead Academic Organization<br> cGMP = cyclic guanosine 30,50-monophosphate</div> <div class="footnote">NOTE: newly launched programs, Translational and Basic Science Research in Early Lesions (<a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="4da000bd-a499-4b5b-910d-cb1d3ff28075" href="/major-programs/translational-and-basic-science-research-early-lesions-tbel-program" title="Translational and Basic Science Research in Early Lesions (TBEL) Program">TBEL</a>) Program, Cancer Prevention-Interception Targeted Agent Discovery Program (<a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="cc43f753-87ee-430a-9d70-843c759cc483" href="/major-programs/cancer-prevention-interception-targeted-agent-discovery-program-cap-it" title="Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT)">CAP-IT</a>), and Cancer Immunoprevention Network (<a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="e17a88dd-f6d1-475d-bed8-5ab59f416768" href="/major-programs/cancer-immunoprevention-network-cip-net" title="Cancer Immunoprevention Network (CIP-Net)">CIP-Net</a>), are not included in the table.</div> <div class="footnote">Reference<br> <br> Sei S et al. <a href="https://pubmed.ncbi.nlm.nih.gov/38562082/">NCI resources for cancer immunoprevention research</a>. <em>Cancer Immunol Res</em> (2024) 12 (4): 387–392.</div></div> </div> </article> </div> </div> </section> </main> 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