Prophylactic Replacement of Voice Prosthesis: A Study to Predict Prosthesis Lifetime

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Voice Prosthesis: A Study to Predict Prosthesis Lifetime</title> <meta name="description" content="Prophylactic Replacement of Voice Prosthesis: A Study to Predict Prosthesis Lifetime"> <meta name="keywords" content="voice prosthesis, voice rehabilitation, total laryngectomy, prosthetic leakage, device lifetime"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img 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publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Prophylactic Replacement of Voice Prosthesis: A Study to Predict Prosthesis Lifetime</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anne%20Heirman">Anne Heirman</a>, <a href="https://publications.waset.org/abstracts/search?q=Vincent%20van%20der%20Noort"> Vincent van der Noort</a>, <a href="https://publications.waset.org/abstracts/search?q=Rob%20van%20Son"> Rob van Son</a>, <a href="https://publications.waset.org/abstracts/search?q=Marije%20Petersen"> Marije Petersen</a>, <a href="https://publications.waset.org/abstracts/search?q=Lisette%20van%20der%20Molen"> Lisette van der Molen</a>, <a href="https://publications.waset.org/abstracts/search?q=Gyorgy%20Halmos"> Gyorgy Halmos</a>, <a href="https://publications.waset.org/abstracts/search?q=Richard%20Dirven"> Richard Dirven</a>, <a href="https://publications.waset.org/abstracts/search?q=Michiel%20van%20den%20Brekel"> Michiel van den Brekel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: Voice prosthesis leakage significantly impacts laryngectomies patients' quality of life, causing insecurity and frequent unplanned hospital visits and costs. In this study, the concept of prophylactic voice prosthesis replacement was explored to prevent leakages. Study Design: A retrospective cohort study. Setting: Tertiary hospital. Methods: Device lifetimes and voice prosthesis replacements of a retrospective cohort, including all patients with laryngectomies between 2000 and 2012 in the Netherlands Cancer Institute, were used to calculate the number of needed voice prostheses per patient per year when preventing 70% of the leakages by prophylactic replacement. Various strategies for the timing of prophylactic replacement were considered: Adaptive strategies based on the individual patient鈥檚 history of replacement and fixed strategies based on the results of patients with similar voice prosthesis or treatment characteristics. Results: Patients used a median of 3.4 voice prostheses per year (range 0.1-48.1). We found a high inter-and intrapatient variability in device lifetime. When applying prophylactic replacement, this would become a median of 9.4 voice prostheses per year, which means replacement every 38 days, implying more than six additional voice prostheses per patient per year. The individual adaptive model showed that preventing 70% of the leakages was impossible for most patients, and only a median of 25% can be prevented. Monte-Carlo simulations showed that prophylactic replacement is not feasible due to the high Coefficient of Variation (Standard Deviation/Mean) in device lifetime. Conclusion: Based on our simulations, prophylactic replacement of voice prostheses is not feasible due to high inter-and intrapatient variation in device lifetime. <iframe src="https://publications.waset.org/abstracts/152896.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=voice%20prosthesis" title="voice prosthesis">voice prosthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=voice%20rehabilitation" title=" voice rehabilitation"> voice rehabilitation</a>, <a href="https://publications.waset.org/abstracts/search?q=total%20laryngectomy" title=" total laryngectomy"> total laryngectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=prosthetic%20leakage" title=" prosthetic leakage"> prosthetic leakage</a>, <a href="https://publications.waset.org/abstracts/search?q=device%20lifetime" title=" device lifetime"> device lifetime</a> </p> 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Prophylactic Replacement of Voice Prosthesis: A Study to Predict Prosthesis Lifetime