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aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Basculer la table des matières" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Basculer la table des matières</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Téniposide</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Aller à un article dans une autre langue. Disponible en 15 langues." > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-15" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">15 langues</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AA%D9%8A%D9%86%D9%8A%D8%A8%D9%88%D8%B3%D9%8A%D8%AF" title="تينيبوسيد – arabe" lang="ar" hreflang="ar" data-title="تينيبوسيد" data-language-autonym="العربية" data-language-local-name="arabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%AA%D9%86%DB%8C%D9%BE%D9%88%D8%B3%D8%A7%DB%8C%D8%AF" title="تنیپوساید – South Azerbaijani" lang="azb" hreflang="azb" data-title="تنیپوساید" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Teniposid" title="Teniposid – gallois" lang="cy" hreflang="cy" data-title="Teniposid" data-language-autonym="Cymraeg" data-language-local-name="gallois" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Teniposid" title="Teniposid – allemand" lang="de" hreflang="de" data-title="Teniposid" data-language-autonym="Deutsch" data-language-local-name="allemand" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Teniposide" title="Teniposide – anglais" lang="en" hreflang="en" data-title="Teniposide" data-language-autonym="English" data-language-local-name="anglais" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Tenip%C3%B3sido" title="Tenipósido – espagnol" lang="es" hreflang="es" data-title="Tenipósido" data-language-autonym="Español" data-language-local-name="espagnol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AA%D9%86%DB%8C%D9%BE%D9%88%D8%B3%D8%A7%DB%8C%D8%AF" title="تنیپوساید – persan" lang="fa" hreflang="fa" data-title="تنیپوساید" data-language-autonym="فارسی" data-language-local-name="persan" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Teniposidi" title="Teniposidi – finnois" lang="fi" hreflang="fi" data-title="Teniposidi" data-language-autonym="Suomi" data-language-local-name="finnois" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Teniposide" title="Teniposide – italien" lang="it" hreflang="it" data-title="Teniposide" data-language-autonym="Italiano" data-language-local-name="italien" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%9F%E0%AD%87%E0%AC%A8%E0%AC%BF%E0%AC%AA%E0%AD%8B%E0%AC%B8%E0%AC%BE%E0%AC%87%E0%AC%A1" title="ଟେନିପୋସାଇଡ – odia" lang="or" hreflang="or" data-title="ଟେନିପୋସାଇଡ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Tenipozid" title="Tenipozid – roumain" lang="ro" hreflang="ro" data-title="Tenipozid" data-language-autonym="Română" data-language-local-name="roumain" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A2%D0%B5%D0%BD%D0%B8%D0%BF%D0%BE%D0%B7%D0%B8%D0%B4" title="Тенипозид – russe" lang="ru" hreflang="ru" data-title="Тенипозид" data-language-autonym="Русский" data-language-local-name="russe" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Tenipozid" title="Tenipozid – serbo-croate" lang="sh" hreflang="sh" data-title="Tenipozid" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbo-croate" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Tenipozid" title="Tenipozid – serbe" lang="sr" hreflang="sr" data-title="Tenipozid" data-language-autonym="Српски / srpski" data-language-local-name="serbe" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Teniposide" title="Teniposide – vietnamien" lang="vi" hreflang="vi" data-title="Teniposide" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamien" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q417555#sitelinks-wikipedia" title="Modifier les liens interlangues" class="wbc-editpage">Modifier les liens</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espaces de noms"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/T%C3%A9niposide" title="Voir le contenu de la page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Discussion:T%C3%A9niposide" rel="discussion" title="Discussion au sujet de cette page de contenu [t]" accesskey="t"><span>Discussion</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Modifier la variante de langue" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">français</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Affichages"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/T%C3%A9niposide"><span>Lire</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit" title="Modifier cette page [v]" accesskey="v"><span>Modifier</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&action=edit" title="Modifier le wikicode de cette page [e]" accesskey="e"><span>Modifier le code</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&action=history" title="Historique des versions de cette page [h]" accesskey="h"><span>Voir l’historique</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Outils de la page"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Outils" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Outils</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Outils</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">déplacer vers la barre latérale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">masquer</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Plus d’options" > <div class="vector-menu-heading"> Actions </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/T%C3%A9niposide"><span>Lire</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit" title="Modifier cette page [v]" accesskey="v"><span>Modifier</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&action=edit" title="Modifier le wikicode de cette page [e]" accesskey="e"><span>Modifier le code</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&action=history"><span>Voir l’historique</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Général </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Pages_li%C3%A9es/T%C3%A9niposide" title="Liste des pages liées qui pointent sur celle-ci [j]" accesskey="j"><span>Pages liées</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Suivi_des_liens/T%C3%A9niposide" rel="nofollow" title="Liste des modifications récentes des pages appelées par celle-ci [k]" accesskey="k"><span>Suivi des pages liées</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Aide:Importer_un_fichier" title="Téléverser des fichiers [u]" accesskey="u"><span>Téléverser un fichier</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Pages_sp%C3%A9ciales" title="Liste de toutes les pages spéciales [q]" accesskey="q"><span>Pages spéciales</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&oldid=215912117" title="Adresse permanente de cette version de cette page"><span>Lien permanent</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&action=info" title="Davantage d’informations sur cette page"><span>Informations sur la page</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:Citer&page=T%C3%A9niposide&id=215912117&wpFormIdentifier=titleform" title="Informations sur la manière de citer cette page"><span>Citer cette page</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:UrlShortener&url=https%3A%2F%2Ffr.wikipedia.org%2Fwiki%2FT%25C3%25A9niposide"><span>Obtenir l'URL raccourcie</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:QrCode&url=https%3A%2F%2Ffr.wikipedia.org%2Fwiki%2FT%25C3%25A9niposide"><span>Télécharger le code QR</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Imprimer / exporter </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:Livre&bookcmd=book_creator&referer=T%C3%A9niposide"><span>Créer un livre</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Sp%C3%A9cial:DownloadAsPdf&page=T%C3%A9niposide&action=show-download-screen"><span>Télécharger comme PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=T%C3%A9niposide&printable=yes" title="Version imprimable de cette page [p]" accesskey="p"><span>Version imprimable</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> Dans d’autres projets </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Teniposide" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q417555" title="Lien vers l’élément dans le dépôt de données connecté [g]" accesskey="g"><span>Élément Wikidata</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Outils de la page"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Apparence"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Apparence</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">déplacer vers la barre latérale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">masquer</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Un article de Wikipédia, l'encyclopédie libre.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="fr" dir="ltr"><p class="mw-empty-elt"> </p> <table class="infobox_v2 infobox infobox--frwiki noarchive"> <tbody><tr> <td colspan="2" class="entete medecine" style="background-color:#6ABF84;color:#000000;">Téniposide<style data-mw-deduplicate="TemplateStyles:r213937691">.mw-parser-output .entete.medecine{background-image:url("//upload.wikimedia.org/wikipedia/commons/2/23/Picto_infobox_med.png")}</style> </td></tr> <tr><td colspan="2" style="text-align:center; line-height: 1.5em;"><span typeof="mw:File/Frameless"><a href="/w/index.php?title=Fichier:Teniposide2DACS.svg&lang=fr" class="mw-file-description"><img alt="Image illustrative de l’article Téniposide" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Teniposide2DACS.svg/langfr-160px-Teniposide2DACS.svg.png" decoding="async" width="160" height="153" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Teniposide2DACS.svg/langfr-240px-Teniposide2DACS.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Teniposide2DACS.svg/langfr-320px-Teniposide2DACS.svg.png 2x" data-file-width="512" data-file-height="490" /></a></span> </td></tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#6ABF84; color:#000000">Informations générales</th></tr> <tr> <th scope="row"><a href="/wiki/M%C3%A9dicament" title="Médicament">Princeps</a> </th> <td>Vumon </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#6ABF84; color:#000000"><a href="/wiki/Pharmacocin%C3%A9tique" title="Pharmacocinétique">Données pharmacocinétiques</a></th></tr> <tr> <th scope="row"><a href="/wiki/Excr%C3%A9tion" title="Excrétion">Excrétion</a> </th> <td> <p>Rein </p> </td> </tr> <tr> <th colspan="2" style="padding:4px; text-align:center; background-color:#6ABF84; color:#000000">Identification</th></tr> <tr> <th scope="row"><a href="/wiki/Num%C3%A9ro_CAS" title="Numéro CAS">N<sup>o</sup> CAS</a> </th> <td><span class="reflink plainlinksneverexpand"><span class="noarchive"><a class="external text" href="//tools.wmflabs.org/magnustools/cas.php?cas=29767-20-2&language=fr&title=Téniposide">29767-20-2</a> <span class="wd_p231"><span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q417555?uselang=fr#P231" title="Voir et modifier les données sur Wikidata"><img alt="Voir et modifier les données sur Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/10px-Blue_pencil.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/15px-Blue_pencil.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/20px-Blue_pencil.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></span></span></span> </td> </tr> <tr> <th scope="row"> N<sup>o</sup> <a href="/wiki/Agence_europ%C3%A9enne_des_produits_chimiques" title="Agence européenne des produits chimiques">ECHA</a> </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="http://echa.europa.eu/fr/substance-information/-/substanceinfo/100.045.286">100.045.286</a></span></span></td> </tr> <tr> <th scope="row"><a href="/wiki/Classification_ATC" title="Classification ATC">Code ATC</a> </th> <td>L01CB02 </td> </tr> <tr> <th scope="row">DrugBank </th> <td><span class="plainlinks"><span class="noarchive"><a rel="nofollow" class="external text" href="http://www.drugbank.ca/drugs/DBDB00444">DB00444</a> <span class="wd_p715"><span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q417555?uselang=fr#P715" title="Voir et modifier les données sur Wikidata"><img alt="Voir et modifier les données sur Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/10px-Blue_pencil.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/15px-Blue_pencil.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/20px-Blue_pencil.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></span></span></span> </td> </tr> <tr> <td class="navigation-only" colspan="2" style="border-top: 2px #6ABF84 solid; font-size: 80%; background:inherit; color: inherit; text-align: right;"><span class="plainlinks" style="float:left;"><a class="external text" href="https://fr.wikipedia.org/w/index.php?title=T%C3%A9niposide&action=edit&section=0"><span class="infodoc">modifier</span></a></span> <span typeof="mw:File"><a href="/wiki/Mod%C3%A8le:Infobox_M%C3%A9dicament" title="Consultez la documentation du modèle"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/12px-Info_Simple.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/18px-Info_Simple.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/24px-Info_Simple.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></td> </tr> </tbody></table> <p>Le <b>téniposide</b> est un médicament <a href="/wiki/Anticanc%C3%A9reux" title="Anticancéreux">anticancéreux</a>. Il est vendu sous la marque Vumon<sup id="cite_ref-AHFS2021_1-0" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Mode_d'action"><span id="Mode_d.27action"></span>Mode d'action</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit&section=1" title="Modifier la section : Mode d'action" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T%C3%A9niposide&action=edit&section=1" title="Modifier le code source de la section : Mode d'action"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Il fait partie d'une classe de médicaments connus sous le nom de dérivés de la <a href="/wiki/Podophyllotoxine" title="Podophyllotoxine">podophyllotoxine</a> et on pense qu'il agit en interférant avec la production de l'ADN<sup id="cite_ref-AHFS2021_1-1" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Usage_médical"><span id="Usage_m.C3.A9dical"></span>Usage médical</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit&section=2" title="Modifier la section : Usage médical" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T%C3%A9niposide&action=edit&section=2" title="Modifier le code source de la section : Usage médical"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Le téniposide est un <a href="/wiki/M%C3%A9dicament" title="Médicament">médicament</a> de <a href="/wiki/Chimioth%C3%A9rapie" title="Chimiothérapie">chimiothérapie</a> utilisé pour traiter la <a href="/wiki/Leuc%C3%A9mie_aigu%C3%AB_lymphoblastique" title="Leucémie aiguë lymphoblastique">leucémie lymphoïde aiguë</a> chez les enfants<sup id="cite_ref-AHFS2021_1-2" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. C'est un agent de deuxième ligne pour cet usage<sup id="cite_ref-AHFS2021_1-3" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. D'autres utilisations peuvent inclure le <a href="/wiki/Cancer_bronchique_%C3%A0_petites_cellules" title="Cancer bronchique à petites cellules">cancer du poumon à petites cellules</a> et le <a href="/wiki/Lymphome" title="Lymphome">lymphome</a><sup id="cite_ref-Rav2011_2-0" class="reference"><a href="#cite_note-Rav2011-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. Le médicament est administré par injection dans une veine<sup id="cite_ref-AHFS2021_1-4" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Effets_secondaires">Effets secondaires</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit&section=3" title="Modifier la section : Effets secondaires" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T%C3%A9niposide&action=edit&section=3" title="Modifier le code source de la section : Effets secondaires"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Les effets secondaires de ce médicament comprennent <a href="/wiki/Leucop%C3%A9nie" title="Leucopénie">un faible nombre de globules blancs</a>, <a href="/wiki/An%C3%A9mie" title="Anémie">un faible nombre de globules rouges</a>, <a href="/wiki/Thrombop%C3%A9nie" title="Thrombopénie">un faible nombre de plaquettes</a>, une inflammation de la bouche, une perte de cheveux, des saignements, de la fièvre ou des <a href="/wiki/Allergie" title="Allergie">réactions allergiques</a> ;<sup id="cite_ref-AHFS2021_1-5" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. D'autres effets secondaires peuvent inclure d'autres cancers, la nécrose cutanée au site d'injection ou <a href="/wiki/Hypotension_art%C3%A9rielle" title="Hypotension artérielle">une hypotension artérielle</a> <sup id="cite_ref-AHFS2021_1-6" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. L'utilisation de ce médicament pendant la grossesse peut nuire au fœtus<sup id="cite_ref-AHFS2021_1-7" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Histoire">Histoire</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit&section=4" title="Modifier la section : Histoire" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T%C3%A9niposide&action=edit&section=4" title="Modifier le code source de la section : Histoire"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Le médicament a été approuvé pour un usage médical aux États-Unis en 1992<sup id="cite_ref-AHFS2021_1-8" class="reference"><a href="#cite_note-AHFS2021-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup>. Il est vendu en Europe depuis 1967 et au Canada depuis 1984<sup id="cite_ref-Rav2011_2-1" class="reference"><a href="#cite_note-Rav2011-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-HC2021_3-0" class="reference"><a href="#cite_note-HC2021-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup>. Aux États-Unis, cela coûte environ 2 100 dollars américains par dose de <span class="nowrap"><span title="">50</span> <span title="milligramme">mg</span></span> à partir de 2021<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup>. Il n'est plus disponible commercialement au Canada<sup id="cite_ref-HC2021_3-1" class="reference"><a href="#cite_note-HC2021-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Références"><span id="R.C3.A9f.C3.A9rences"></span>Références</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit&section=5" title="Modifier la section : Références" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T%C3%A9niposide&action=edit&section=5" title="Modifier le code source de la section : Références"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-AHFS2021-1"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-AHFS2021_1-0">a</a> <a href="#cite_ref-AHFS2021_1-1">b</a> <a href="#cite_ref-AHFS2021_1-2">c</a> <a href="#cite_ref-AHFS2021_1-3">d</a> <a href="#cite_ref-AHFS2021_1-4">e</a> <a href="#cite_ref-AHFS2021_1-5">f</a> <a href="#cite_ref-AHFS2021_1-6">g</a> <a href="#cite_ref-AHFS2021_1-7">h</a> et <a href="#cite_ref-AHFS2021_1-8">i</a></sup> </span><span class="reference-text"><span class="ouvrage"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <span class="noarchive">« <a rel="nofollow" class="external text" href="https://www.drugs.com/monograph/teniposide.html"><cite style="font-style:normal;" lang="en">Teniposide Monograph for Professionals</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20190816160737/https://www.drugs.com/monograph/teniposide.html">archive du <time class="nowrap" datetime="2019-08-16" data-sort-value="2019-08-16">16 août 2019</time></a>]</small></span>, <span class="italique">Drugs.com</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2021-09-25" data-sort-value="2021-09-25">25 septembre 2021</time>)</small></span></span> </li> <li id="cite_note-Rav2011-2"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-Rav2011_2-0">a</a> et <a href="#cite_ref-Rav2011_2-1">b</a></sup> </span><span class="reference-text"><span class="ouvrage" id="Ravina2011"><span class="ouvrage" id="Enrique_Ravina2011"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Enrique <span class="nom_auteur">Ravina</span>, <cite class="italique" lang="en">The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs</cite>, John Wiley & Sons, <time class="nowrap" datetime="2011-04-18" data-sort-value="2011-04-18">18 avril 2011</time> <small style="line-height:1em;">(<a href="/wiki/International_Standard_Book_Number" title="International Standard Book Number">ISBN</a> <a href="/wiki/Sp%C3%A9cial:Ouvrages_de_r%C3%A9f%C3%A9rence/978-3-527-32669-3" title="Spécial:Ouvrages de référence/978-3-527-32669-3"><span class="nowrap">978-3-527-32669-3</span></a>, <span class="noarchive"><a rel="nofollow" class="external text" href="https://www.google.ca/books/edition/The_Evolution_of_Drug_Discovery/iDNy0XxGqT8C?hl=en&gbpv=1&dq=Teniposide+Europe&pg=PA156">lire en ligne</a> <small class="cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20210925182927/https://www.google.ca/books/edition/The_Evolution_of_Drug_Discovery/iDNy0XxGqT8C?hl=en&gbpv=1&dq=Teniposide+Europe&pg=PA156">archive du <time class="nowrap" datetime="2021-09-25" data-sort-value="2021-09-25">25 septembre 2021</time></a>]</small></span>)</small>, <abbr class="abbr" title="page">p.</abbr> 156<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Evolution+of+Drug+Discovery%3A+From+Traditional+Medicines+to+Modern+Drugs&rft.pub=John+Wiley+%26+Sons&rft.aulast=Ravina&rft.aufirst=Enrique&rft.date=2011-04-18&rft.pages=156&rft.isbn=978-3-527-32669-3&rfr_id=info%3Asid%2Ffr.wikipedia.org%3AT%C3%A9niposide"></span></span></span></span> </li> <li id="cite_note-HC2021-3"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-HC2021_3-0">a</a> et <a href="#cite_ref-HC2021_3-1">b</a></sup> </span><span class="reference-text"><span class="ouvrage" id="of_Canada2012"><span class="ouvrage" id="Government_of_Canada2012">Government of Canada, <span class="noarchive">« <a rel="nofollow" class="external text" href="https://health-products.canada.ca/dpd-bdpp/info.do?lang=en&code=5995"><cite style="font-style:normal;">Drug Product Database Online Query</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20210927021220/https://health-products.canada.ca/dpd-bdpp/info.do?lang=en&code=5995">archive du <time class="nowrap" datetime="2021-09-27" data-sort-value="2021-09-27">27 septembre 2021</time></a>]</small></span>, <span class="italique">health-products.canada.ca</span>, <time class="nowrap" datetime="2012-04-25" data-sort-value="2012-04-25">25 avril 2012</time> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2021-09-26" data-sort-value="2021-09-26">26 septembre 2021</time>)</small></span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink noprint"><a href="#cite_ref-4">↑</a> </span><span class="reference-text"><span class="ouvrage"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <span class="noarchive">« <a rel="nofollow" class="external text" href="https://www.drugs.com/price-guide/teniposide"><cite style="font-style:normal;" lang="en">Teniposide Prices, Coupons & Patient Assistance Programs</cite></a> » <small class="plainlinks cachelinks">[<a rel="nofollow" class="external text" href="https://web.archive.org/web/20210124201631/https://www.drugs.com/price-guide/teniposide">archive du <time class="nowrap" datetime="2021-01-24" data-sort-value="2021-01-24">24 janvier 2021</time></a>]</small></span>, <span class="italique">Drugs.com</span> <small style="line-height:1em;">(consulté le <time class="nowrap" datetime="2021-09-25" data-sort-value="2021-09-25">25 septembre 2021</time>)</small></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Liens_externes">Liens externes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T%C3%A9niposide&veaction=edit&section=6" title="Modifier la section : Liens externes" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T%C3%A9niposide&action=edit&section=6" title="Modifier le code source de la section : Liens externes"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p class="mw-empty-elt"> </p> <ul><li class="mw-empty-elt"></li> <li><span class="liste-horizontale noarchive"><span class="wd_identifiers">Ressources relatives à la santé<span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q417555?uselang=fr#identifiers" title="Voir et modifier les données sur Wikidata"><img alt="Voir et modifier les données sur Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/10px-Blue_pencil.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/15px-Blue_pencil.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/20px-Blue_pencil.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></span> : <ul><li><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL452231"><span class="lang-en" lang="en">ChEMBL</span></a></li> <li><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DBDB00444"><span class="lang-en" lang="en">DrugBank</span></a></li> <li><a rel="nofollow" class="external text" href="http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6843"><span class="lang-en" lang="en">International Union of Pharmacology</span></a></li> <li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D013713"><span class="lang-en" lang="en">Medical Subject Headings</span></a></li> <li><a rel="nofollow" class="external text" href="http://bioportal.bioontology.org/ontologies/NDFRT?p=classes&conceptid=N0000148273"><span class="lang-en" lang="en">National Drug File</span></a></li> <li><a rel="nofollow" class="external text" href="https://www.patientslikeme.com/treatments/show/teniposide"><span class="lang-en" lang="en">PatientLikeMe</span></a></li> </ul></span> </li> <li class="mw-empty-elt"></li> <li class="mw-empty-elt"></li></ul> <table class="navbox collapsible noprint autocollapse" style=""> <tbody><tr><th class="navbox-title" colspan="2" style=""><div style="float:left; width:6em; text-align:left"><div class="noprint plainlinks nowrap tnavbar" style="padding:0; font-size:xx-small; color:var(--color-emphasized, #000000);"><a href="/wiki/Mod%C3%A8le:Palette_Agents_anticanc%C3%A9reux_intracellulaires" title="Modèle:Palette Agents anticancéreux intracellulaires"><abbr class="abbr" title="Voir ce modèle.">v</abbr></a> · <a class="external text" href="https://fr.wikipedia.org/w/index.php?title=Mod%C3%A8le:Palette_Agents_anticanc%C3%A9reux_intracellulaires&action=edit"><abbr class="abbr" title="Modifier ce modèle. Merci de prévisualiser avant de sauvegarder.">m</abbr></a></div></div><div style="font-size:110%">Agents anticancéreux intracellulaires / <a href="/wiki/Classe_ATC_L01" title="Classe ATC L01">ATC code L01</a></div></th> </tr> <tr> <th class="navbox-group" style="width:20em">Inhibiteur de la <a href="/wiki/R%C3%A9plication_de_l%27ADN" title="Réplication de l'ADN">réplication de l'ADN</a></th> <td class="navbox-list" style=""><table class="navbox-subgroup" style=""> <tbody><tr> <th class="navbox-group" style=""><a href="/wiki/Agent_alkylant_antin%C3%A9oplasique" title="Agent alkylant antinéoplasique">Agents alkylants</a></th> <td class="navbox-list" style=";"><table class="navbox-subgroup" style=""> <tbody><tr> <th class="navbox-group" style=""><a href="/wiki/Sel_de_platine" title="Sel de platine">Sels de platine</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Carboplatine" title="Carboplatine">Carboplatine</a></li> <li><a href="/wiki/Cisplatine" title="Cisplatine">Cisplatine</a></li> <li><a href="/wiki/Oxaliplatine" title="Oxaliplatine">Oxaliplatine</a></li> <li><a href="/w/index.php?title=Dicycloplatine&action=edit&redlink=1" class="new" title="Dicycloplatine (page inexistante)">Dicycloplatine</a></li> <li><a href="/w/index.php?title=Nedaplatine&action=edit&redlink=1" class="new" title="Nedaplatine (page inexistante)">Nedaplatine</a></li> <li><a href="/w/index.php?title=Satraplatine&action=edit&redlink=1" class="new" title="Satraplatine (page inexistante)">Satraplatine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Moutarde_azot%C3%A9e" title="Moutarde azotée">Moutardes azotées</a></th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Bendamustine" title="Bendamustine">Bendamustine</a></li> <li><a href="/wiki/Chlorm%C3%A9thine" title="Chlorméthine">Chlorméthine</a></li> <li><a href="/wiki/Chlorambucil" title="Chlorambucil">Chlorambucil</a></li> <li><a href="/wiki/Cyclophosphamide" title="Cyclophosphamide">Cyclophosphamide</a></li> <li><a href="/wiki/Ifosfamide" title="Ifosfamide">Ifosfamide</a></li> <li><a href="/wiki/Melphalan" title="Melphalan">Melphalan</a></li> <li><a href="/wiki/Chlorm%C3%A9thine" title="Chlorméthine">Méchloréthamine</a></li> <li><a href="/wiki/T%C3%A9mozolomide" title="Témozolomide">Témozolomide</a></li> <li><a href="/wiki/Prednimustine" title="Prednimustine">Prednimustine</a></li> <li><a href="/wiki/Uramustine" title="Uramustine">Uramustine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Nitrosour%C3%A9e" title="Nitrosourée">Nitrosourées</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Carmustine" title="Carmustine">Carmustine</a></li> <li><a href="/wiki/Fot%C3%A9mustine" title="Fotémustine">Fotémustine</a></li> <li><a href="/wiki/Streptozotocine" title="Streptozotocine">Streptozotocine</a></li> <li><a href="/wiki/Lomustine" title="Lomustine">Lomustine</a></li> <li><a href="/w/index.php?title=Nimustine&action=edit&redlink=1" class="new" title="Nimustine (page inexistante)">Nimustine</a> <a href="https://en.wikipedia.org/wiki/Nimustine" class="extiw" title="en:Nimustine"><span class="indicateur-langue" title="Article en anglais : « Nimustine »">(en)</span></a></li> <li><a href="/w/index.php?title=Ranimustine&action=edit&redlink=1" class="new" title="Ranimustine (page inexistante)">Ranimustine</a> <a href="https://en.wikipedia.org/wiki/Ranimustine" class="extiw" title="en:Ranimustine"><span class="indicateur-langue" title="Article en anglais : « Ranimustine »">(en)</span></a></li> <li><a href="/wiki/Uramustine" title="Uramustine">Uramustine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Sulfonate_d%27alkyle" title="Sulfonate d'alkyle">Sulfonates d'alkyle</a></th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Busulfan" title="Busulfan">Busulfan</a> <ul><li><a href="/w/index.php?title=Mannosulfan&action=edit&redlink=1" class="new" title="Mannosulfan (page inexistante)">Mannosulfan</a></li> <li><a href="/wiki/Tr%C3%A9osulfan" title="Tréosulfan">Tréosulfan</a></li></ul></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Aziridine" title="Aziridine">Aziridines</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/w/index.php?title=Carboquone&action=edit&redlink=1" class="new" title="Carboquone (page inexistante)">Carboquone</a> <a href="https://en.wikipedia.org/wiki/Carboquone" class="extiw" title="en:Carboquone"><span class="indicateur-langue" title="Article en anglais : « Carboquone »">(en)</span></a></li> <li><a href="/w/index.php?title=Thiotepa&action=edit&redlink=1" class="new" title="Thiotepa (page inexistante)">Thiotepa</a> <a href="https://en.wikipedia.org/wiki/Thiotepa" class="extiw" title="en:Thiotepa"><span class="indicateur-langue" title="Article en anglais : « Thiotepa »">(en)</span></a></li> <li><a href="/w/index.php?title=Triaziquone&action=edit&redlink=1" class="new" title="Triaziquone (page inexistante)">Triaziquone</a> <a href="https://en.wikipedia.org/wiki/Triaziquone" class="extiw" title="en:Triaziquone"><span class="indicateur-langue" title="Article en anglais : « Triaziquone »">(en)</span></a></li> <li><a href="/w/index.php?title=Tri%C3%A9thylenemelamine&action=edit&redlink=1" class="new" title="Triéthylenemelamine (page inexistante)">Triéthylenemelamine</a> <a href="https://en.wikipedia.org/wiki/Triethylenemelamine" class="extiw" title="en:Triethylenemelamine"><span class="indicateur-langue" title="Article en anglais : « Triethylenemelamine »">(en)</span></a></li></ul> </div></td> </tr> </tbody></table></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Antim%C3%A9tabolite" title="Antimétabolite">Antimétabolites</a></th> <td class="navbox-list navbox-even" style=";"><table class="navbox-subgroup" style=""> <tbody><tr> <th class="navbox-group" style="">Inhibiteur de la <a href="/wiki/Dihydrofolate_r%C3%A9ductase" title="Dihydrofolate réductase">dihydrofolate réductase</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/M%C3%A9thotrexate" title="Méthotrexate">Méthotrexate</a></li> <li><a href="/wiki/Aminopt%C3%A9rine" title="Aminoptérine">Aminoptérine</a></li> <li><a href="/wiki/P%C3%A9m%C3%A9trexed" title="Pémétrexed">Pémétrexed</a></li> <li><a href="/w/index.php?title=Pralatrexate&action=edit&redlink=1" class="new" title="Pralatrexate (page inexistante)">Pralatrexate</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Inhibiteur de la <a href="/wiki/Thymidylate_synthase" title="Thymidylate synthase">Thymidylate synthase</a></th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Fluorouracile" title="Fluorouracile">Fluorouracile</a></li> <li><a href="/wiki/P%C3%A9m%C3%A9trexed" title="Pémétrexed">Pémétrexed</a></li> <li><a href="/w/index.php?title=Raltitrexed&action=edit&redlink=1" class="new" title="Raltitrexed (page inexistante)">Raltitrexed</a></li> <li><a href="/wiki/Cap%C3%A9citabine" title="Capécitabine">Capécitabine</a></li> <li><a href="/w/index.php?title=Carmofur&action=edit&redlink=1" class="new" title="Carmofur (page inexistante)">Carmofur</a></li> <li><a href="/w/index.php?title=Doxifluridine&action=edit&redlink=1" class="new" title="Doxifluridine (page inexistante)">Doxifluridine</a></li> <li><a href="/wiki/Floxuridine" title="Floxuridine">Floxuridine</a></li> <li><a href="/wiki/T%C3%A9gafur" title="Tégafur">Tegafur</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Inhibiteur de la <a href="/wiki/Ribonucl%C3%A9otide_r%C3%A9ductase" title="Ribonucléotide réductase">RNR</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Cladribine" title="Cladribine">Cladribine</a></li> <li><a href="/wiki/Clofarabine" title="Clofarabine">Clofarabine</a></li> <li><a href="/wiki/Fludarabine" title="Fludarabine">Fludarabine</a></li> <li><a href="/wiki/N%C3%A9larabine" title="Nélarabine">Nélarabine</a></li> <li><a href="/wiki/Gemcitabine" title="Gemcitabine">Gemcitabine</a></li> <li><a href="/wiki/Hydroxyur%C3%A9e" title="Hydroxyurée">Hydroxyurée</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Inhibiteur de <a href="/wiki/R%C3%A9action_en_cha%C3%AEne_par_polym%C3%A9rase" title="Réaction en chaîne par polymérase">PCR</a></th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Cytarabine" title="Cytarabine">Cytarabine</a></li> <li><a href="/wiki/Daunorubicine" title="Daunorubicine">Daunorubicine</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Inhibiteur de <a href="/wiki/M%C3%A9thylation" title="Méthylation">méthylation</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><a href="/wiki/Azacitidine" title="Azacitidine">Azacitidine</a></li> <li><a href="/wiki/D%C3%A9citabine" title="Décitabine">Décitabine</a></li></ul> </div></td> </tr> </tbody></table></td> </tr> <tr> <th class="navbox-group" style=""><a href="/wiki/Inhibiteur_de_topoisom%C3%A9rase" title="Inhibiteur de topoisomérase">Inhibiteurs de topoisomérase</a></th> <td class="navbox-list" style=";"><table class="navbox-subgroup" style=""> <tbody><tr> <th class="navbox-group" style="">I</th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><i><a href="/w/index.php?title=Camptotheca&action=edit&redlink=1" class="new" title="Camptotheca (page inexistante)">Camptotheca</a> <a href="https://en.wikipedia.org/wiki/Camptotheca" class="extiw" title="en:Camptotheca"><span class="indicateur-langue" title="Article en anglais : « Camptotheca »">(en)</span></a></i> <ul><li><a href="/wiki/Irinot%C3%A9can" title="Irinotécan">Irinotécan</a></li> <li><a href="/wiki/Topot%C3%A9can" title="Topotécan">Topotécan</a></li></ul></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">II</th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><i><a href="/wiki/Podophyllum" title="Podophyllum">Podophyllum</a></i> <ul><li><a href="/wiki/%C3%89toposide" title="Étoposide">Étoposide</a></li> <li><a class="mw-selflink selflink">Téniposide</a></li></ul></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">II + <a href="/wiki/Intercalation_(biochimie)" title="Intercalation (biochimie)">Intercalation</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><i><a href="/w/index.php?title=Antibiotique_antitumoral&action=edit&redlink=1" class="new" title="Antibiotique antitumoral (page inexistante)">Antibiotiques antitumoraux</a></i> <ul><li><a href="/wiki/Bl%C3%A9omycine" title="Bléomycine">Bléomycine</a></li> <li><a href="/wiki/Daunorubicine" title="Daunorubicine">Daunorubicine</a></li> <li><a href="/wiki/Doxorubicine" title="Doxorubicine">Doxorubicine</a></li> <li><a href="/wiki/%C3%89pirubicine" title="Épirubicine">Épirubicine</a></li> <li><a href="/wiki/Hydroxyur%C3%A9e" title="Hydroxyurée">Hydroxyurée</a></li> <li><a href="/wiki/Idarubicine" title="Idarubicine">Idarubicine</a></li> <li><a href="/wiki/Mitomycine_C" title="Mitomycine C">Mitomycine C</a></li> <li><a href="/wiki/Mitoxantrone" title="Mitoxantrone">Mitoxantrone</a></li></ul></li></ul> </div></td> </tr> </tbody></table></td> </tr> </tbody></table></td> </tr> <tr> <th class="navbox-group" style="width:20em">Poisons du <a href="/wiki/Fuseau_mitotique" title="Fuseau mitotique">fuseau mitotique</a> (<a href="/wiki/Antimitotique" title="Antimitotique">antimitotiques</a>)</th> <td class="navbox-list navbox-even" style=""><table class="navbox-subgroup" style=""> <tbody><tr> <th class="navbox-group" style="">Bloqueur de l'assemblage des <a href="/wiki/Microtubule" title="Microtubule">microtubules</a></th> <td class="navbox-list" style=";"><div class="liste-horizontale"> <ul><li><i><a href="/wiki/Alcalo%C3%AFde" title="Alcaloïde">Alcaloïdes végétaux</a></i> <ul><li><a href="/wiki/Vinblastine" title="Vinblastine">Vinblastine</a></li> <li><a href="/wiki/Vincristine" title="Vincristine">Vincristine</a></li> <li><a href="/wiki/Vinorelbine" title="Vinorelbine">Vinorelbine</a></li> <li><a href="/wiki/Vind%C3%A9sine" title="Vindésine">Vindésine</a></li> <li><a href="/w/index.php?title=Vinflunine&action=edit&redlink=1" class="new" title="Vinflunine (page inexistante)">Vinflunine</a></li></ul></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="">Bloqueur du désassemblage des <a href="/wiki/Microtubule" title="Microtubule">microtubules</a></th> <td class="navbox-list navbox-even" style=";"><div class="liste-horizontale"> <ul><li><i><a href="/wiki/Taxane" title="Taxane">Taxanes</a></i> <ul><li><a href="/wiki/Doc%C3%A9taxel" title="Docétaxel">Docétaxel</a></li> <li><a href="/wiki/Paclitaxel" title="Paclitaxel">Paclitaxel</a></li> <li><a href="/wiki/Cabazitaxel" title="Cabazitaxel">Cabazitaxel</a></li> <li><a href="/w/index.php?title=Larotaxel&action=edit&redlink=1" class="new" title="Larotaxel (page inexistante)">Larotaxel</a></li> <li><a href="/w/index.php?title=Tesetaxel&action=edit&redlink=1" class="new" title="Tesetaxel (page inexistante)">Tesetaxel</a></li></ul></li> <li><i><a href="/wiki/%C3%89pothilone" title="Épothilone">Épothilones</a></i> <ul><li><a href="/w/index.php?title=Ixabepilone&action=edit&redlink=1" class="new" title="Ixabepilone (page inexistante)">Ixabepilone</a></li></ul></li></ul> </div></td> </tr> </tbody></table></td> </tr> <tr> <th class="navbox-group" style="width:20em"><a href="/wiki/Th%C3%A9rapie_photodynamique" title="Thérapie photodynamique">Thérapie photodynamique</a></th> <td class="navbox-list" style=""><div class="liste-horizontale"> <ul><li><a href="/wiki/Acide_%CE%B4-aminol%C3%A9vulinique" title="Acide δ-aminolévulinique">Acide δ-aminolévulinique</a></li> <li><a href="/w/index.php?title=%C3%89faproxiral&action=edit&redlink=1" class="new" title="Éfaproxiral (page inexistante)">Éfaproxiral</a></li> <li><a href="/w/index.php?title=Aminol%C3%A9vulinate_de_m%C3%A9thyle&action=edit&redlink=1" class="new" title="Aminolévulinate de méthyle (page inexistante)">Aminolévulinate de méthyle</a></li> <li><i><a href="/wiki/Porphyrine" title="Porphyrine">Porphyrines</a></i> <ul><li><a href="/w/index.php?title=Porfim%C3%A8re_sodique&action=edit&redlink=1" class="new" title="Porfimère sodique (page inexistante)">Porfimère sodique</a></li> <li><a href="/w/index.php?title=Padeliporfine&action=edit&redlink=1" class="new" title="Padeliporfine (page inexistante)">Padeliporfine</a></li> <li><a href="/w/index.php?title=Talaporfine&action=edit&redlink=1" class="new" title="Talaporfine (page inexistante)">Talaporfine</a></li> <li><a href="/w/index.php?title=Temoporfine&action=edit&redlink=1" class="new" title="Temoporfine (page inexistante)">Temoporfine</a></li> <li><a href="/w/index.php?title=Verteporfine&action=edit&redlink=1" class="new" title="Verteporfine (page inexistante)">Verteporfine</a></li></ul></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="width:20em"><a href="/wiki/Inhibiteur_de_kinase" title="Inhibiteur de kinase">Inhibiteurs de protéine kinase</a></th> <td class="navbox-list navbox-even" style=""><div class="liste-horizontale"> <ul><li><a href="/wiki/Imatinib" title="Imatinib">Imatinib</a></li> <li><a href="/wiki/G%C3%A9fitinib" title="Géfitinib">Géfitinib</a></li> <li><a href="/wiki/Erlotinib" title="Erlotinib">Erlotinib</a></li> <li><a href="/wiki/Sunitinib" title="Sunitinib">Sunitinib</a></li> <li><a href="/wiki/Soraf%C3%A9nib" title="Sorafénib">Sorafénib</a></li> <li><a href="/wiki/Dasatinib" title="Dasatinib">Dasatinib</a></li> <li><a href="/w/index.php?title=Lapatinib&action=edit&redlink=1" class="new" title="Lapatinib (page inexistante)">Lapatinib</a></li> <li><a href="/wiki/Nilotinib" title="Nilotinib">Nilotinib</a></li> <li><a href="/wiki/Temsirolimus" title="Temsirolimus">Temsirolimus</a></li> <li><a href="/wiki/%C3%89v%C3%A9rolimus" title="Évérolimus">Évérolimus</a></li> <li><a href="/wiki/Pazopanib" title="Pazopanib">Pazopanib</a></li> <li><a href="/wiki/Vand%C3%A9tanib" title="Vandétanib">Vandétanib</a></li> <li><a href="/wiki/Afatinib" title="Afatinib">Afatinib</a></li> <li><a href="/wiki/Bosutinib" title="Bosutinib">Bosutinib</a></li> <li><a href="/wiki/Vemurafenib" title="Vemurafenib">Vemurafenib</a></li> <li><a href="/wiki/Crizotinib" title="Crizotinib">Crizotinib</a></li> <li><a href="/wiki/Axitinib" title="Axitinib">Axitinib</a></li> <li><a href="/wiki/Ruxolitinib" title="Ruxolitinib">Ruxolitinib</a></li> <li><a href="/w/index.php?title=Ridaforolimus&action=edit&redlink=1" class="new" title="Ridaforolimus (page inexistante)">Ridaforolimus</a></li> <li><a href="/wiki/R%C3%A9goraf%C3%A9nib" title="Régorafénib">Régorafénib</a></li> <li><a href="/wiki/Masitinib" title="Masitinib">Masitinib</a></li> <li><a href="/wiki/Dabrafenib" title="Dabrafenib">Dabrafénib</a></li> <li><a href="/wiki/Ponatinib" title="Ponatinib">Ponatinib</a></li> <li><a href="/wiki/Trametinib" title="Trametinib">Tramétinib</a></li> <li><a href="/wiki/Cabozantinib" title="Cabozantinib">Cabozantinib</a></li></ul> </div></td> </tr> <tr> <th class="navbox-group" style="width:20em">Autres</th> <td class="navbox-list" style=""><div class="liste-horizontale"> <ul><li><a href="/wiki/Aflibercept" title="Aflibercept">Aflibercept</a></li> <li><a href="/wiki/Anhydride_ars%C3%A9nieux" title="Anhydride arsénieux">Anhydride arsénieux</a></li> <li><i><a href="/wiki/Asparagine" title="Asparagine">Asparagine depleters</a></i> <ul><li><a href="/wiki/Asparaginase" title="Asparaginase">Asparaginase</a></li> <li><a href="/w/index.php?title=Pegaspargase&action=edit&redlink=1" class="new" title="Pegaspargase (page inexistante)">Pegaspargase</a> <a href="https://en.wikipedia.org/wiki/Pegaspargase" class="extiw" title="en:Pegaspargase"><span class="indicateur-langue" title="Article en anglais : « Pegaspargase »">(en)</span></a></li></ul></li> <li><a href="/wiki/Axicabtagene_ciloleucel" title="Axicabtagene ciloleucel">Axicabtagene ciloleucel</a></li> <li><a href="/wiki/Belzutifan" title="Belzutifan">Belzutifan</a></li> <li><a href="/wiki/Bexarot%C3%A8ne" title="Bexarotène">Bexarotène</a></li> <li><a href="/wiki/C%C3%A9l%C3%A9coxib" title="Célécoxib">Célécoxib</a></li> <li><a href="/w/index.php?title=Demecolcine&action=edit&redlink=1" class="new" title="Demecolcine (page inexistante)">Demecolcine</a></li> <li><a href="/w/index.php?title=Denileukin_diftitox&action=edit&redlink=1" class="new" title="Denileukin diftitox (page inexistante)">Denileukin diftitox</a></li> <li><a href="/w/index.php?title=Elesclomol&action=edit&redlink=1" class="new" title="Elesclomol (page inexistante)">Elesclomol</a></li> <li><a href="/w/index.php?title=Elsamitrucin&action=edit&redlink=1" class="new" title="Elsamitrucin (page inexistante)">Elsamitrucin</a></li> <li><a href="/wiki/%C3%89nasid%C3%A9nib" title="Énasidénib">Énasidénib</a></li> <li><a href="/w/index.php?title=Epacadostat&action=edit&redlink=1" class="new" title="Epacadostat (page inexistante)">Epacadostat</a></li> <li><a href="/wiki/%C3%89ribuline" title="Éribuline">Éribuline</a></li> <li><a href="/w/index.php?title=Estramustine_phosphate&action=edit&redlink=1" class="new" title="Estramustine phosphate (page inexistante)">Estramustine phosphate</a></li> <li><a href="/wiki/Ivosid%C3%A9nib" title="Ivosidénib">Ivosidénib</a></li> <li><a href="/w/index.php?title=Lonidamine&action=edit&redlink=1" class="new" title="Lonidamine (page inexistante)">Lonidamine</a></li> <li><a href="/w/index.php?title=Lucanthone&action=edit&redlink=1" class="new" title="Lucanthone (page inexistante)">Lucanthone</a></li> <li><a href="/w/index.php?title=Lurbinectedine&action=edit&redlink=1" class="new" title="Lurbinectedine (page inexistante)">Lurbinectedine</a></li> <li><a href="/w/index.php?title=Mitoguazone&action=edit&redlink=1" class="new" title="Mitoguazone (page inexistante)">Mitoguazone</a></li> <li><a href="/wiki/Dichlorodiph%C3%A9nyldichloro%C3%A9thane" title="Dichlorodiphényldichloroéthane">Mitotane</a></li> <li><a href="/w/index.php?title=Oblimersen&action=edit&redlink=1" class="new" title="Oblimersen (page inexistante)">Oblimersen</a></li> <li><a href="/w/index.php?title=Omacetaxine_mepesuccinate&action=edit&redlink=1" class="new" title="Omacetaxine mepesuccinate (page inexistante)">Omacetaxine mepesuccinate</a></li> <li><a href="/wiki/Plitidepsine" title="Plitidepsine">Plitidepsine</a></li> <li><i><a href="/wiki/R%C3%A9tino%C3%AFde" title="Rétinoïde">Rétinoïdes</a></i> <ul><li><a href="/w/index.php?title=Alitr%C3%A9tinoine&action=edit&redlink=1" class="new" title="Alitrétinoine (page inexistante)">Alitrétinoine</a></li> <li><a href="/wiki/Bexarot%C3%A8ne" title="Bexarotène">Bexarotène</a></li> <li><a href="/wiki/Tr%C3%A9tino%C3%AFne" title="Trétinoïne">Trétinoïne</a></li></ul></li> <li><a href="/wiki/S%C3%A9linexor" title="Sélinexor">Sélinexor</a></li> <li><a href="/w/index.php?title=Sitimagene_ceradenovec&action=edit&redlink=1" class="new" title="Sitimagene ceradenovec (page inexistante)">Sitimagene ceradenovec</a></li> <li><a href="/w/index.php?title=Sotorasib&action=edit&redlink=1" class="new" title="Sotorasib (page inexistante)">Sotorasib</a></li> <li><a href="/w/index.php?title=Tagraxofusp&action=edit&redlink=1" class="new" title="Tagraxofusp (page inexistante)">Tagraxofusp</a></li> <li><a href="/w/index.php?title=Talimogene_laherparepvec&action=edit&redlink=1" class="new" title="Talimogene laherparepvec (page inexistante)">Talimogene laherparepvec</a></li> <li><a href="/w/index.php?title=Tazemetostat&action=edit&redlink=1" class="new" title="Tazemetostat (page inexistante)">Tazemetostat</a></li> <li><a href="/wiki/Tiazofurine" title="Tiazofurine">Tiazofurine</a></li> <li><a href="/w/index.php?title=Tigilanol_tiglate&action=edit&redlink=1" class="new" title="Tigilanol tiglate (page inexistante)">Tigilanol tiglate</a></li> <li><a href="/wiki/Tisagenlecleucel" title="Tisagenlecleucel">Tisagenlecleucel</a></li> <li><a href="/wiki/Trabect%C3%A9dine" title="Trabectédine">Trabectédine</a></li> <li><a href="/w/index.php?title=Veliparib&action=edit&redlink=1" class="new" title="Veliparib (page inexistante)">Veliparib</a></li> <li><a href="/wiki/V%C3%A9n%C3%A9toclax" title="Vénétoclax">Vénétoclax</a></li> <li><a href="/w/index.php?title=Verdinexor&action=edit&redlink=1" class="new" title="Verdinexor (page inexistante)">Verdinexor</a></li> <li><a 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