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data-event-name="pinnable-header.vector-toc.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">hide</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">(Top)</div> </a> </li> <li id="toc-Types" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Types"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Types</span> </div> </a> <ul id="toc-Types-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Symptoms_and_signs" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Symptoms_and_signs"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Symptoms and signs</span> </div> </a> <ul id="toc-Symptoms_and_signs-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Location" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Location"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Location</span> </div> </a> <button aria-controls="toc-Location-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Location subsection</span> </button> <ul id="toc-Location-sublist" class="vector-toc-list"> <li id="toc-Ocular_myxoma" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Ocular_myxoma"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Ocular myxoma</span> </div> </a> <ul id="toc-Ocular_myxoma-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Atrial_myxoma" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Atrial_myxoma"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.2</span> <span>Atrial myxoma</span> </div> </a> <ul id="toc-Atrial_myxoma-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Treatment" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Treatment"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Treatment</span> </div> </a> <ul id="toc-Treatment-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Epidemiology" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Epidemiology"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Epidemiology</span> </div> </a> <ul id="toc-Epidemiology-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div 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<div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Myxoid tumor of primitive connective tissue</div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">For the atrial subtype, see <a href="/wiki/Atrial_myxoma" class="mw-redirect" title="Atrial myxoma">Atrial myxoma</a>. For the virus, see <a href="/wiki/Myxoma_virus" title="Myxoma virus">Myxoma virus</a>.</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">"Myxomatous" redirects here. Not to be confused with <a href="/wiki/Myxomatosis" title="Myxomatosis">Myxomatosis</a>.</div> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Medical condition</div><style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox ib-medical-condition"><tbody><tr><th colspan="2" class="infobox-above" style="background:#ccc">Myxoma</th></tr><tr style="background-color: #f8f9fa;"><td colspan="2" class="infobox-full-data"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Atrial_myxoma_high_mag.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/Atrial_myxoma_high_mag.jpg/220px-Atrial_myxoma_high_mag.jpg" decoding="async" width="220" height="147" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/Atrial_myxoma_high_mag.jpg/330px-Atrial_myxoma_high_mag.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/95/Atrial_myxoma_high_mag.jpg/440px-Atrial_myxoma_high_mag.jpg 2x" data-file-width="4272" data-file-height="2848" /></a></span></td></tr><tr><td colspan="2" class="infobox-full-data"><a href="/wiki/Micrograph" title="Micrograph">Micrograph</a> of an <a href="/wiki/Atrial_myxoma" class="mw-redirect" title="Atrial myxoma">atrial myxoma</a>. <a href="/wiki/H%26E_stain" title="H&E stain">H&E stain</a>.</td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Medical_specialty" title="Medical specialty">Specialty</a></th><td class="infobox-data"><a href="/wiki/Oncology" title="Oncology">Oncology</a> <span class="penicon autoconfirmed-show"><span class="mw-valign-text-top" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q589612?uselang=en#P1995" title="Edit this on Wikidata"><img alt="Edit this on Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></td></tr></tbody></table> <p>A <b>myxoma</b> (<a href="/wiki/New_Latin" class="mw-redirect" title="New Latin">New Latin</a> from <a href="/wiki/Ancient_Greek" title="Ancient Greek">Greek</a> <span title="Ancient Greek (to 1453)-language text"><i lang="grc-Latn">muxa</i></span> '<a href="/wiki/Mucus" title="Mucus">mucus</a>') is a <a href="/wiki/Myxoid_tumor" title="Myxoid tumor">myxoid tumor</a> of primitive <a href="/wiki/Connective_tissue" title="Connective tissue">connective tissue</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> It is most commonly found in the heart (and is the most common primary tumor of the <a href="/wiki/Heart" title="Heart">heart</a> in adults) but can also occur in other locations. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Types">Types</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=1" title="Edit section: Types"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Table below:<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <table class="wikitable"> <tbody><tr> <th>Myxoma </th> <th>Margin </th> <th>Vascular pattern </th> <th>Cellularity </th> <th><a href="/wiki/Stroma_(animal_tissue)" class="mw-redirect" title="Stroma (animal tissue)">Stroma</a> </th> <th><a href="/wiki/Staining" title="Staining">Staining</a> characteristics </th> <th>Recurrence rate </th> <th>Image (see <a href="/wiki/Histology" title="Histology">Histology</a>) </th></tr> <tr> <td><a href="/wiki/Cutaneous_myxoma" title="Cutaneous myxoma">Cutaneous myxoma</a> or Superficial angiomyxoma </td> <td>Poor to moderately circumscribed, multilobular </td> <td>Scattered thin-walled vessels </td> <td>Moderately cellular, bland spindled and <a href="/wiki/Stellate_cell" title="Stellate cell">stellate cells</a>, variable inflammatory cell infiltrate </td> <td>Abundant mucin with clefts. Up to 30% have an associated epithelial component </td> <td><a href="/wiki/Vimentin" title="Vimentin">Vimentin</a>; variable staining with <a href="/wiki/CD34" title="CD34">CD34</a>, <a href="/wiki/Factor_XIII" title="Factor XIII">factor XIII</a>A, SMA<sup class="plainlinks nourlexpansion citation" id="ref_1"><a href="#endnote_1">1</a></sup>, MSA<sup class="plainlinks nourlexpansion citation" id="ref_2"><a href="#endnote_2">2</a></sup> and <a href="/wiki/S-100_protein" class="mw-redirect" title="S-100 protein">S-100</a> </td> <td>20–30% </td> <td><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/File:CutaneousMyxoma.jpg" class="mw-file-description" title="Cutaneous Myxoma"><img alt="Cutaneous Myxoma" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/CutaneousMyxoma.jpg/100px-CutaneousMyxoma.jpg" decoding="async" width="100" height="63" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/CutaneousMyxoma.jpg/150px-CutaneousMyxoma.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3e/CutaneousMyxoma.jpg/200px-CutaneousMyxoma.jpg 2x" data-file-width="1712" data-file-height="1084" /></a><figcaption>Cutaneous Myxoma</figcaption></figure> </td></tr> <tr> <td>Intramuscular myxoma </td> <td>Poorly circumscribed merges with surrounding muscle </td> <td>Hypovascular variant; hypervascular variant </td> <td>Hypocellular variant; hypercellular variant; bland spindle cells </td> <td>Abundant mucin with cystic spaces. Hypercellular variant has strands of collagen </td> <td>Vimentin; variable staining with <a href="/wiki/Actin" title="Actin">actin</a>, <a href="/wiki/Desmin" title="Desmin">desmin</a>, CD34 </td> <td>None </td> <td><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/File:IntramuscularMyxoma.JPG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/7/75/IntramuscularMyxoma.JPG/100px-IntramuscularMyxoma.JPG" decoding="async" width="100" height="75" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/75/IntramuscularMyxoma.JPG/150px-IntramuscularMyxoma.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/75/IntramuscularMyxoma.JPG/200px-IntramuscularMyxoma.JPG 2x" data-file-width="2048" data-file-height="1536" /></a><figcaption></figcaption></figure> </td></tr> <tr> <td>Juxta-articular myxoma </td> <td>Poorly circumscribed infiltrates surrounding tissue </td> <td>Focally vascular </td> <td>Focally hypercellular, peripheral spindle cells with occasional atypical cells and mitoses </td> <td>Abundant mucin, 89% of cases contain cystic spaces lined by fibrin or collagen </td> <td>Vimentin; variable staining with actin, desmin, CD34 </td> <td>34% </td></tr> <tr> <td>Aggressive <a href="/wiki/Angiomyxoma" class="mw-redirect" title="Angiomyxoma">angiomyxoma</a> </td> <td>Infiltrative </td> <td>Uniformly distributed medium-sized blood vessels often with prominent hyalinization </td> <td>Low to moderately cellular, evenly distributed round, spindled or stellate cells </td> <td>Loose myxoid to focally collagenous </td> <td>Vimentin, desmin, SMA<sup class="plainlinks nourlexpansion citation" id="ref_1"><a href="#endnote_1">1</a></sup>, MSA<sup class="plainlinks nourlexpansion citation" id="ref_2"><a href="#endnote_2">2</a></sup>, estrogen and progesterone receptor </td> <td>36–72% </td></tr> <tr> <td>Angiomyofibroblastoma </td> <td>Well circumscribed </td> <td>Abundant thin-walled blood vessels </td> <td>Alternating hypercellular and hypocellular areas, perivascular condensations of spindled to epithelioid <a href="/wiki/Stromal_cells" class="mw-redirect" title="Stromal cells">stromal cells</a> </td> <td>Collagenous to edematous with minimal mucin </td> <td>Vimentin, desmin, CD34, estrogen and <a href="/wiki/Progesterone_receptor" title="Progesterone receptor">progesterone receptor</a> </td> <td>No recurrences reported, but rare cases of sarcomatous degeneration </td></tr> <tr> <td><a href="/wiki/Superficial_acral_fibromyxoma" title="Superficial acral fibromyxoma">Superficial acral fibromyxoma</a> </td> <td>Pushing to infiltrative </td> <td>Mild to moderately accentuated vasculature </td> <td>Moderately cellular, spindle and stellate cells with a <a href="/wiki/Storiform" class="mw-redirect" title="Storiform">storiform</a> to fascicular pattern, variable mast cells </td> <td>Myxoid to collagenous </td> <td>CD34, <a href="/wiki/Epithelial_membrane_antigen" class="mw-redirect" title="Epithelial membrane antigen">EMA</a><sup class="noprint Inline-Template" style="margin-left:0.1em; white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Please_clarify" title="Wikipedia:Please clarify"><span title="The text near this tag may need clarification or removal of jargon. (July 2012)">clarification needed</span></a></i>]</sup><sup class="plainlinks nourlexpansion citation" id="ref_3"><a href="#endnote_3">3</a></sup>, <a href="/wiki/CD99" title="CD99">CD99</a> </td> <td>Recurrence rare and primarily for incompletely excised lesions </td></tr> <tr> <td><a href="/wiki/Neurothekeoma" title="Neurothekeoma">Neurothekeoma</a> (Nerve sheath myxoma) </td> <td>Well circumscribed, multilobular </td> <td>Hypovascular </td> <td>Moderately cellular, spindled cells in fascicles and whorls </td> <td>Nests of cells separated by collagenous bundles </td> <td>S-100, EMA<sup class="plainlinks nourlexpansion citation" id="ref_3"><a href="#endnote_3">3</a></sup> </td> <td>47% if incompletely excised </td> <td><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/File:Neurothekeoma2.JPG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/54/Neurothekeoma2.JPG/100px-Neurothekeoma2.JPG" decoding="async" width="100" height="75" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/54/Neurothekeoma2.JPG/150px-Neurothekeoma2.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/54/Neurothekeoma2.JPG/200px-Neurothekeoma2.JPG 2x" data-file-width="2048" data-file-height="1536" /></a><figcaption></figcaption></figure> </td></tr></tbody></table> <p>1.<style data-mw-deduplicate="TemplateStyles:r1041539562">.mw-parser-output .citation{word-wrap:break-word}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}</style><span class="citation wikicite" id="endnote_1"><b><a href="#ref_1">^</a></b></span> SMA, <a href="/wiki/Smooth_muscle" title="Smooth muscle">smooth muscle</a> <a href="/wiki/Actin" title="Actin">actin</a>. 2.<link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1041539562"><span class="citation wikicite" id="endnote_2"><b><a href="#ref_2">^</a></b></span> MSA, muscle-specific <a href="/wiki/Actin" title="Actin">actin</a>. 3.<link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1041539562"><span class="citation wikicite" id="endnote_3"><b><a href="#ref_3">^</a></b></span> EMA, <a href="/wiki/MUC1" class="mw-redirect" title="MUC1">epithelial membrane antigen</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Symptoms_and_signs">Symptoms and signs</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=2" title="Edit section: Symptoms and signs"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Symptoms associated with cardiac myxomas are typically due to the effect of the mass of the tumor obstructing the normal flow of blood within the chambers of the heart. Because pedunculated myxomas are somewhat mobile, symptoms may only occur when the patient is in a particular position. </p><p>Some symptoms of myxoma may be associated with the release of <a href="/wiki/Interleukin_6" title="Interleukin 6">interleukin 6</a> (IL-6) by the myxoma.<sup id="cite_ref-Seino-IL6_3-0" class="reference"><a href="#cite_note-Seino-IL6-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Jourdan-IL6_4-0" class="reference"><a href="#cite_note-Jourdan-IL6-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> High levels of IL-6 may be associated with a higher risk of <a href="/wiki/Embolism" title="Embolism">embolism</a> of the myxoma.<sup id="cite_ref-Wada-IL6_5-0" class="reference"><a href="#cite_note-Wada-IL6-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Symptoms of a cardiac myxoma include:<sup id="cite_ref-Fisher-Cardiacmyxoma_6-0" class="reference"><a href="#cite_note-Fisher-Cardiacmyxoma-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <ul><li><a href="/wiki/Dyspnea" class="mw-redirect" title="Dyspnea">Dyspnea</a> on exertion</li> <li><a href="/wiki/Paroxysmal_nocturnal_dyspnea" class="mw-redirect" title="Paroxysmal nocturnal dyspnea">Paroxysmal nocturnal dyspnea</a></li> <li><a href="/wiki/Fever" title="Fever">Fever</a></li> <li><a href="/wiki/Weight_loss" title="Weight loss">Weight loss</a> (see <a href="/wiki/Cachexia" title="Cachexia">cachexia</a>)</li> <li>Lightheadedness or <a href="/wiki/Syncope_(medicine)" title="Syncope (medicine)">syncope</a> (Loss of consciousness)</li> <li><a href="/wiki/Hemoptysis" title="Hemoptysis">Hemoptysis</a></li> <li>Sudden death</li> <li><a href="/wiki/Tachycardia" title="Tachycardia">Tachycardia</a> or milder heartrate, i.e. 75–100 cycl/min</li></ul> <div class="mw-heading mw-heading2"><h2 id="Location">Location</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=3" title="Edit section: Location"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Myxoma_CMR.gif" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/1/14/Myxoma_CMR.gif/220px-Myxoma_CMR.gif" decoding="async" width="220" height="147" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/1/14/Myxoma_CMR.gif 1.5x" data-file-width="300" data-file-height="200" /></a><figcaption>Animated image of an <a href="/wiki/MRI" class="mw-redirect" title="MRI">MRI</a> of the heart, showing a large myxoma plunging to and fro from atrium to ventricle across the mitral valve.</figcaption></figure> <div class="mw-heading mw-heading3"><h3 id="Ocular_myxoma">Ocular myxoma</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=4" title="Edit section: Ocular myxoma"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Conjunctival myxomas are thought to originate in <a href="/wiki/Tenon%27s_capsule" title="Tenon's capsule">Tenon's capsule</a> and can masquerade as <a href="/w/index.php?title=Conjunctival_lymphoma&action=edit&redlink=1" class="new" title="Conjunctival lymphoma (page does not exist)">conjunctival lymphoma</a>, <a href="/wiki/Lymphangioma" class="mw-redirect" title="Lymphangioma">lymphangioma</a>, <a href="/wiki/Ocular_surface_squamous_neoplasia" class="mw-redirect" title="Ocular surface squamous neoplasia">ocular surface squamous neoplasia</a> (OSSN), or <a href="/wiki/Amelanotic_melanoma" title="Amelanotic melanoma">amelanotic melanoma</a>.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <ul><li><a href="/wiki/Atrial_myxoma" class="mw-redirect" title="Atrial myxoma">Atrial myxoma</a></li> <li><a href="/wiki/Cutaneous_myxoma" title="Cutaneous myxoma">Cutaneous myxoma</a></li> <li><a href="/wiki/Odontogenic_myxoma" title="Odontogenic myxoma">Odontogenic myxoma</a></li></ul> <figure class="mw-default-size mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/File:Myxoma.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/20/Myxoma.jpg/220px-Myxoma.jpg" decoding="async" width="220" height="156" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/20/Myxoma.jpg/330px-Myxoma.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/20/Myxoma.jpg/440px-Myxoma.jpg 2x" data-file-width="722" data-file-height="512" /></a><figcaption>A myxoma. A gelatinous tumor can be seen attached by a narrow pedicle to the atrial septum. The myxoma has an irregular surface and nearly fills the left atrium.</figcaption></figure> <div class="mw-heading mw-heading3"><h3 id="Atrial_myxoma">Atrial myxoma</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=5" title="Edit section: Atrial myxoma"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Myxomas are usually located in either the <a href="/wiki/Left_atrium" class="mw-redirect" title="Left atrium">left</a> or <a href="/wiki/Right_atrium" class="mw-redirect" title="Right atrium">right atrium</a> of the heart; about 86 percent occur in the <a href="/wiki/Left_atrium" class="mw-redirect" title="Left atrium">left atrium</a>.<sup id="cite_ref-pmid3188128_8-0" class="reference"><a href="#cite_note-pmid3188128-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p><p>Myxomas are typically <a href="/wiki/Pedunculated" class="mw-redirect" title="Pedunculated">pedunculated</a>, with a stalk that is attached to the <a href="/wiki/Interatrial_septum" title="Interatrial septum">interatrial septum</a>. The most common location for attachment of the stalk is the <a href="/wiki/Fossa_ovalis_(heart)" title="Fossa ovalis (heart)">fossa ovalis</a> region of the interatrial septum.<sup id="cite_ref-Cheng_9-0" class="reference"><a href="#cite_note-Cheng-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p><p>An <a href="/wiki/Atrial_myxoma" class="mw-redirect" title="Atrial myxoma">atrial myxoma</a> may create an extra <a href="/wiki/Heart_sounds" title="Heart sounds">heart sound</a>, audible to <a href="/wiki/Auscultation" title="Auscultation">auscultation</a> just after <a href="/wiki/S2_(heart_sound)" class="mw-redirect" title="S2 (heart sound)">S2</a>. It is most seen on <a href="/wiki/Echocardiography" title="Echocardiography">echocardiography</a>, as a pedunculated mass that is heterogeneous in appearance. A left atrial myxoma will cause an increase in <a href="/wiki/Pulmonary_wedge_pressure" title="Pulmonary wedge pressure">pulmonary capillary wedge pressure</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2021)">citation needed</span></a></i>]</sup> </p><p>The <a href="/wiki/Differential_diagnosis" title="Differential diagnosis">differential diagnosis</a> include other cardiac tumors such as <a href="/wiki/Lipoma" title="Lipoma">lipomas</a> and <a href="/wiki/Rhabdomyoma" title="Rhabdomyoma">rhabdomyomas</a> (and rarely <a href="/wiki/Teratoma" title="Teratoma">teratomas</a>). These other tumors of the heart are typically not pedunculated, however, and are more likely to <a href="/wiki/Infiltration_(medical)" title="Infiltration (medical)">infiltrate</a> the muscle of the heart. Cardiac <a href="/wiki/Magnetic_resonance_imaging" title="Magnetic resonance imaging">magnetic resonance imaging</a> (MRI) can help non-invasively diagnose cardiac tumors. However, diagnosis usually requires examination of a <a href="/wiki/Biopsy" title="Biopsy">tissue sample</a> by a <a href="/wiki/Pathologist" class="mw-redirect" title="Pathologist">pathologist</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2021)">citation needed</span></a></i>]</sup> </p> <div style="clear:both;" class=""></div> <div class="mw-heading mw-heading2"><h2 id="Treatment">Treatment</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=6" title="Edit section: Treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Myxomas are usually removed surgically. The surgeon removes the myxoma, along with at least 5 surrounding millimeters of atrial septum. The septum is then repaired, using material from the <a href="/wiki/Pericardium" title="Pericardium">pericardium</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2021)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading2"><h2 id="Epidemiology">Epidemiology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=7" title="Edit section: Epidemiology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Cardiac myxomas predominantly appear in females in their 30s to 40s. Myxomas are the most common primary cardiac tumor affecting adults,<sup id="cite_ref-Cheng_9-1" class="reference"><a href="#cite_note-Cheng-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> accounting for one quarter to half of primary cardiac tumors seen in clinical practice.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=8" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Myxoid_tumor" title="Myxoid tumor">Myxoid tumor</a></li> <li><a href="/wiki/Cutaneous_myxoma" title="Cutaneous myxoma">Cutaneous myxoma</a></li> <li><a href="/wiki/Carney_complex" title="Carney complex">Carney complex</a></li> <li><a href="/wiki/Myxomatosis" title="Myxomatosis">Myxomatosis</a></li> <li><a href="/wiki/Primary_tumors_of_the_heart" title="Primary tumors of the heart">Primary tumors of the heart</a></li> <li><a href="/wiki/Myxomatous_degeneration" class="mw-redirect" title="Myxomatous degeneration">Myxomatous degeneration</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=9" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20090628224336/http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/nine/000954944.htm">"Myxoma"</a> at <i><a href="/wiki/Dorland%27s_medical_reference_works" title="Dorland's medical reference works">Dorland's Medical Dictionary</a></i></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFSatter2009" class="citation journal cs1">Satter, Elizabeth K. 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A 12-year experience and review"</a>. <i>Stroke</i>. <b>19</b> (11): 1435–40. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1161%2F01.str.19.11.1435">10.1161/01.str.19.11.1435</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3188128">3188128</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Stroke&rft.atitle=Neurologic+manifestations+of+atrial+myxoma.+A+12-year+experience+and+review&rft.volume=19&rft.issue=11&rft.pages=1435-40&rft.date=1988&rft_id=info%3Adoi%2F10.1161%2F01.str.19.11.1435&rft_id=info%3Apmid%2F3188128&rft.aulast=Knepper&rft.aufirst=LE&rft.au=Biller%2C+J&rft.au=Adams%2C+HP&rft.au=Bruno%2C+A&rft_id=https%3A%2F%2Fdoi.org%2F10.1161%252F01.str.19.11.1435&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMyxoma" class="Z3988"></span></span> </li> <li id="cite_note-Cheng-9"><span class="mw-cite-backlink">^ <a href="#cite_ref-Cheng_9-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Cheng_9-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChengMartinDavid2020" class="citation book cs1">Cheng, Davy C.H.; Martin, Janet; David, Tirone (2020). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=-44HEAAAQBAJ&pg=PA210"><i>Evidence-Based Practice in Perioperative Cardiac Anesthesia and Surgery</i></a>. 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mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Myxoma&action=edit&section=10" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://www.merck.com/mmhe/sec03/ch031/ch031b.html">03-031b.</a> at <i><a href="/wiki/Merck_Manual_of_Diagnosis_and_Therapy" title="Merck Manual of Diagnosis and Therapy">Merck Manual of Diagnosis and Therapy</a></i> Home Edition</li> <li><a rel="nofollow" class="external text" href="https://www.wikidoc.org/index.php/Myxomatous_degeneration">Myxomatous degeneration at Wikidoc</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 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.hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist 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ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-label="Navbox" style="width:100%; margin:0.5em 0 0.5em 0;;padding:3px"><table class="nowraplinks navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background: #EAECF0;color:black;">Classification</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><div style="position:relative; float:right; font-size:0.8em;"><a href="https://www.wikidata.org/wiki/Q589612" class="extiw" title="d:Q589612">D</a></div><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/International_Statistical_Classification_of_Diseases_and_Related_Health_Problems" class="mw-redirect" title="International Statistical Classification of Diseases and Related Health Problems">ICD</a>-<a href="/wiki/ICD-10" title="ICD-10">10</a></b>: <a rel="nofollow" class="external text" href="https://icd.who.int/browse10/2019/en#/D21.9">D21.9</a></li><li><b><a href="/wiki/International_Statistical_Classification_of_Diseases_and_Related_Health_Problems" class="mw-redirect" title="International Statistical Classification of Diseases and Related Health Problems">ICD</a>-<a href="/wiki/List_of_ICD-9_codes" title="List of ICD-9 codes">9-CM</a></b>: <a rel="nofollow" class="external text" href="http://www.icd9data.com/getICD9Code.ashx?icd9=212.7">212.7</a></li><li><b><a href="/wiki/International_Classification_of_Diseases_for_Oncology" title="International Classification of Diseases for Oncology">ICD-O</a></b>: <a rel="nofollow" class="external text" href="https://progenetix.org/subsets/?term_id=icdom:8840_0">M8840/0</a></li><li><b><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></b>: <a rel="nofollow" class="external text" href="https://omim.org/entry/255960">255960</a></li><li><b><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></b>: <a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D009232">D009232</a></li><li><b><a href="/wiki/Diseases_Database" title="Diseases Database">DiseasesDB</a></b>: <a rel="nofollow" class="external text" href="http://www.diseasesdatabase.com/ddb30736.htm">30736</a></li><li><b><a href="/wiki/SNOMED_CT" title="SNOMED CT">SNOMED CT</a></b>: <a rel="nofollow" class="external text" href="http://snomed.info/id/404082003">404082003</a></li></ul></div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: #EAECF0;color:black;">External resources</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/EMedicine" title="EMedicine">eMedicine</a></b>: <a rel="nofollow" class="external text" href="https://emedicine.medscape.com/med/186-overview">med/186</a></li></ul></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Connective/soft_tissue_tumors_and_sarcomas" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Soft_tissue_tumors_and_sarcomas" title="Template:Soft tissue tumors and sarcomas"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Soft_tissue_tumors_and_sarcomas" title="Template talk:Soft tissue tumors and sarcomas"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Soft_tissue_tumors_and_sarcomas" title="Special:EditPage/Template:Soft tissue tumors and sarcomas"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Connective/soft_tissue_tumors_and_sarcomas" style="font-size:114%;margin:0 4em"><a href="/wiki/Connective_tissue" title="Connective tissue">Connective</a>/<a href="/wiki/Soft_tissue" title="Soft tissue">soft tissue</a> <a href="/wiki/Neoplasm" title="Neoplasm">tumors</a> and <a href="/wiki/Sarcoma" title="Sarcoma">sarcomas</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Not otherwise specified</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Soft-tissue_sarcoma" title="Soft-tissue sarcoma">Soft-tissue sarcoma</a></li> <li><a href="/wiki/Desmoplastic_small-round-cell_tumor" title="Desmoplastic small-round-cell tumor">Desmoplastic small-round-cell tumor</a></li> <li><a href="/wiki/Skin_sarcoma" title="Skin sarcoma">Skin sarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Connective_tissue_neoplasm" title="Connective tissue neoplasm">Connective tissue neoplasm</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fibrous_tissue_neoplasm" title="Fibrous tissue neoplasm">Fibromatous</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fibroma" title="Fibroma">Fibroma</a>/<a href="/wiki/Fibrosarcoma" title="Fibrosarcoma">fibrosarcoma</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Dermatofibrosarcoma_protuberans" title="Dermatofibrosarcoma protuberans">Dermatofibrosarcoma protuberans</a></li> <li><a href="/wiki/Desmoplastic_fibroma" title="Desmoplastic fibroma">Desmoplastic fibroma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fibroma" title="Fibroma">Fibroma</a>/<a href="/wiki/Fibromatosis" title="Fibromatosis">fibromatosis</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aggressive_fibromatosis" title="Aggressive fibromatosis">Aggressive fibromatosis</a></li> <li><a href="/wiki/Aggressive_infantile_fibromatosis" class="mw-redirect" title="Aggressive infantile fibromatosis">Aggressive infantile fibromatosis</a></li> <li><a href="/wiki/Aponeurotic_fibroma" title="Aponeurotic fibroma">Aponeurotic fibroma</a></li> <li><a href="/wiki/Collagenous_fibroma" title="Collagenous fibroma">Collagenous fibroma</a></li> <li><a href="/wiki/Diffuse_infantile_fibromatosis" title="Diffuse infantile fibromatosis">Diffuse infantile fibromatosis</a></li> <li>Familial myxovascular fibromas</li> <li><a href="/wiki/Fibroma_of_tendon_sheath" title="Fibroma of tendon sheath">Fibroma of tendon sheath</a></li> <li><a href="/wiki/Fibromatosis_colli" title="Fibromatosis colli">Fibromatosis colli</a></li> <li><a href="/wiki/Infantile_digital_fibromatosis" title="Infantile digital fibromatosis">Infantile digital fibromatosis</a></li> <li><a href="/wiki/Juvenile_hyaline_fibromatosis" title="Juvenile hyaline fibromatosis">Juvenile hyaline fibromatosis</a></li> <li><a href="/wiki/Plantar_fibromatosis" title="Plantar fibromatosis">Plantar fibromatosis</a></li> <li><a href="/wiki/Pleomorphic_fibroma" title="Pleomorphic fibroma">Pleomorphic fibroma</a></li> <li><a href="/wiki/Oral_submucous_fibrosis" title="Oral submucous fibrosis">Oral submucous fibrosis</a></li> <li><a href="/wiki/Pachydermodactyly" title="Pachydermodactyly">Pachydermodactyly</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Histiocytoma" title="Histiocytoma">Histiocytoma</a>/<a href="/wiki/Histiocytic_sarcoma" title="Histiocytic sarcoma">histiocytic sarcoma</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Benign_fibrous_histiocytoma" class="mw-redirect" title="Benign fibrous histiocytoma">Benign fibrous histiocytoma</a></li> <li><a href="/wiki/Pleomorphic_undifferentiated_sarcoma" class="mw-redirect" title="Pleomorphic undifferentiated sarcoma">Malignant fibrous histiocytoma</a></li> <li><a href="/wiki/Atypical_fibroxanthoma" title="Atypical fibroxanthoma">Atypical fibroxanthoma</a></li> <li><a href="/wiki/Solitary_fibrous_tumor" title="Solitary fibrous tumor">Solitary fibrous tumor</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a class="mw-selflink selflink">Myxomatous</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a class="mw-selflink selflink">Myxoma</a>/<a href="/wiki/Myxosarcoma" title="Myxosarcoma">myxosarcoma</a> <ul><li><a href="/wiki/Cutaneous_myxoma" title="Cutaneous myxoma">Cutaneous myxoma</a></li> <li><a href="/wiki/Superficial_acral_fibromyxoma" title="Superficial acral fibromyxoma">Superficial acral fibromyxoma</a></li></ul></li> <li><a href="/wiki/Aggressive_angiomyxoma" title="Aggressive angiomyxoma">Angiomyxoma</a></li> <li><a href="/wiki/Ossifying_fibromyxoid_tumour" title="Ossifying fibromyxoid tumour">Ossifying fibromyxoid tumour</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fibroepithelial_neoplasms" class="mw-redirect" title="Fibroepithelial neoplasms">Fibroepithelial</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Brenner_tumour" title="Brenner tumour">Brenner tumour</a></li> <li><a href="/wiki/Fibroadenoma" title="Fibroadenoma">Fibroadenoma</a></li> <li><a href="/wiki/Phyllodes_tumor" title="Phyllodes tumor">Phyllodes tumor</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Synovial_joint" title="Synovial joint">Synovial</a>-like</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Synovial_sarcoma" title="Synovial sarcoma">Synovial sarcoma</a></li> <li><a href="/wiki/Clear-cell_sarcoma" class="mw-redirect" title="Clear-cell sarcoma">Clear-cell sarcoma</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Adipose_tissue_neoplasm" title="Adipose tissue neoplasm">Lipomatous</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lipoma" title="Lipoma">Lipoma</a>/<a href="/wiki/Liposarcoma" title="Liposarcoma">liposarcoma</a> <ul><li><a href="/wiki/Myelolipoma" title="Myelolipoma">Myelolipoma</a></li> <li><a href="/wiki/Myxoid_liposarcoma" title="Myxoid liposarcoma">Myxoid liposarcoma</a></li></ul></li> <li><a href="/wiki/Perivascular_epithelioid_cell_tumour" title="Perivascular epithelioid cell tumour">PEComa</a> <ul><li><a href="/wiki/Angiomyolipoma" title="Angiomyolipoma">Angiomyolipoma</a></li></ul></li></ul> <ul><li><a href="/wiki/Chondroid_lipoma" title="Chondroid lipoma">Chondroid lipoma</a></li> <li><a href="/wiki/Intradermal_spindle_cell_lipoma" class="mw-redirect" title="Intradermal spindle cell lipoma">Intradermal spindle cell lipoma</a></li> <li><a href="/wiki/Pleomorphic_lipoma" title="Pleomorphic lipoma">Pleomorphic lipoma</a></li> <li><a href="/wiki/Lipoblastomatosis" title="Lipoblastomatosis">Lipoblastomatosis</a></li> <li><a href="/wiki/Spindle_cell_lipoma" title="Spindle cell lipoma">Spindle cell lipoma</a></li> <li><a href="/wiki/Hibernoma" title="Hibernoma">Hibernoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Muscle_tissue_neoplasm" class="mw-redirect" title="Muscle tissue neoplasm">Myomatous</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><span class="nobold">General</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Myoma" title="Myoma">Myoma</a>/<a href="/wiki/Myosarcoma" title="Myosarcoma">myosarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="nobold"><a href="/wiki/Smooth_muscle_tissue" class="mw-redirect" title="Smooth muscle tissue">Smooth muscle</a></span></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leiomyoma" title="Leiomyoma">Leiomyoma</a>/<a href="/wiki/Leiomyosarcoma" title="Leiomyosarcoma">leiomyosarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="nobold"><a href="/wiki/Skeletal_muscle" title="Skeletal muscle">Skeletal muscle</a></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Rhabdomyoma" title="Rhabdomyoma">Rhabdomyoma</a>/<a href="/wiki/Rhabdomyosarcoma" title="Rhabdomyosarcoma">rhabdomyosarcoma</a>: <a href="/wiki/Embryonal_rhabdomyosarcoma" title="Embryonal rhabdomyosarcoma">Embryonal rhabdomyosarcoma</a> <ul><li><a href="/wiki/Sarcoma_botryoides" title="Sarcoma botryoides">Sarcoma botryoides</a></li></ul></li> <li><a href="/wiki/Alveolar_rhabdomyosarcoma" title="Alveolar rhabdomyosarcoma">Alveolar rhabdomyosarcoma</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leiomyoma" title="Leiomyoma">Leiomyoma</a> <ul><li><a href="/wiki/Cutaneous_leiomyoma" title="Cutaneous leiomyoma">Cutaneous</a></li></ul></li> <li><a href="/wiki/Angioleiomyoma" title="Angioleiomyoma">Angioleiomyoma</a></li> <li><a href="/wiki/Angiolipoleiomyoma" title="Angiolipoleiomyoma">Angiolipoleiomyoma</a></li> <li><a href="/wiki/Genital_leiomyoma" title="Genital leiomyoma">Genital leiomyoma</a></li> <li><a href="/wiki/Leiomyosarcoma" title="Leiomyosarcoma">Leiomyosarcoma</a></li> <li><a href="/wiki/Hereditary_leiomyomatosis_and_renal_cell_cancer_syndrome" title="Hereditary leiomyomatosis and renal cell cancer syndrome">Multiple cutaneous and uterine leiomyomatosis syndrome</a></li> <li><a href="/wiki/Multiple_cutaneous_leiomyoma" class="mw-redirect" title="Multiple cutaneous leiomyoma">Multiple cutaneous leiomyoma</a></li> <li><a href="/wiki/Neural_fibrolipoma" title="Neural fibrolipoma">Neural fibrolipoma</a></li> <li><a href="/wiki/Solitary_cutaneous_leiomyoma" class="mw-redirect" title="Solitary cutaneous leiomyoma">Solitary cutaneous leiomyoma</a></li> <li><a href="/wiki/Smooth_muscle_tumor_of_uncertain_malignant_potential" title="Smooth muscle tumor of uncertain malignant potential">STUMP</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Complex_and_mixed_tumor" class="mw-redirect" title="Complex and mixed tumor">Complex mixed and stromal</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adenomyoma" title="Adenomyoma">Adenomyoma</a></li> <li><a href="/wiki/Pleomorphic_adenoma" title="Pleomorphic adenoma">Pleomorphic adenoma</a></li> <li><a href="/wiki/Mixed_M%C3%BCllerian_tumor" title="Mixed Müllerian tumor">Mixed Müllerian tumor</a></li> <li><a href="/wiki/Mesoblastic_nephroma" title="Mesoblastic nephroma">Mesoblastic nephroma</a></li> <li><a href="/wiki/Wilms%27_tumor" title="Wilms' tumor">Wilms' tumor</a></li> <li><a href="/wiki/Malignant_rhabdoid_tumour" title="Malignant rhabdoid tumour">Malignant rhabdoid tumour</a></li> <li><a href="/wiki/Clear-cell_sarcoma_of_the_kidney" title="Clear-cell sarcoma of the kidney">Clear-cell sarcoma of the kidney</a></li> <li><a href="/wiki/Hepatoblastoma" title="Hepatoblastoma">Hepatoblastoma</a></li> <li><a href="/wiki/Pancreatoblastoma" title="Pancreatoblastoma">Pancreatoblastoma</a></li> <li><a href="/wiki/Carcinosarcoma" title="Carcinosarcoma">Carcinosarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Mesothelium" title="Mesothelium">Mesothelial</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mesothelioma" title="Mesothelioma">Mesothelioma</a></li> <li><a href="/wiki/Adenomatoid_tumor" title="Adenomatoid tumor">Adenomatoid tumor</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Cancers_from_and_involving_the_heart" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse 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involving the heart</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Primary_tumors_of_the_heart" title="Primary tumors of the heart">Primary</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Papillary_fibroelastoma" title="Papillary fibroelastoma">Papillary fibroelastoma</a></li> <li><a href="/wiki/Rhabdomyoma" title="Rhabdomyoma">Rhabdomyoma</a></li> <li><a href="/wiki/Angiosarcoma" title="Angiosarcoma">Angiosarcoma</a></li> <li><a href="/wiki/Teratoma" title="Teratoma">Teratoma</a></li> <li><a href="/wiki/Cystic_tumour_of_the_atrioventricular_nodal_region" title="Cystic tumour of the atrioventricular nodal region">Cystic tumour of the atrioventricular nodal region</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even hlist" 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