CINXE.COM

<!doctype html> <html lang="en"> <head> <meta charset="utf-8"> <meta name="viewport" content="width=device-width"> <title>Oncolytic Viral Vaccine | Comparative Biosciences, inc</title> <meta name="Description" content="Comparative Biosciences, inc."> <link rel="apple-touch-icon" sizes="180x180" href="https://www.compbio.com/images/favicons/apple-touch-icon.png"> <link rel="icon" type="image/png" sizes="32x32" href="https://www.compbio.com/images/favicons/favicon-32x32.png"> <link rel="icon" type="image/png" sizes="16x16" href="https://www.compbio.com/images/favicons/favicon-16x16.png"> <link rel="manifest" href="https://www.compbio.com/images/favicons/site.webmanifest"> <link rel="mask-icon" href="https://www.compbio.com/images/favicons/safari-pinned-tab.svg" color=""> <meta name="msapplication-TileColor" content="#"> <meta name="theme-color" content=""> <link rel="stylesheet" href="https://www.compbio.com/css/style.css?v=1720118533"> <link rel="stylesheet" href="https://www.compbio.com/css/interior.css?v=1658942705"> <link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/font-awesome/4.4.0/css/font-awesome.min.css"> <script>var $site = "https://www.compbio.com", $page = "oncolytic-viral-vaccine", $template = "interior-sidebar", $mods = "https://www.genesisglobalgrp.com/mods/";</script> <script type="module">var body=document.querySelector("body");function show(b,c,a){document.querySelector(b).classList.toggle(c),null!==a&&a()}function lazyLoadImages(){for(var b=document.querySelectorAll(".preload"),c=new IntersectionObserver(function(d){for(var b=0;b<d.length;b++)if(!0===d[b].isIntersecting){var a=d[b].target,e=a.getAttribute("data-src"),f=a.getAttribute("data-srcset");null!==e&&(a.src=e),null!==f&&(a.srcset=f),a.classList.add("loaded"),c.unobserve(a)}}),a=0;a<b.length;a++)c.observe(b[a])}window.addEventListener("load",function(){body.classList.add("loaded"),window.show=show}),document.addEventListener("DOMContentLoaded",lazyLoadImages,!1);var inView=new IntersectionObserver(function(a){for(i=0;i<a.length;i++)!0===a[i].isIntersecting&&a[i].target.parentNode.classList.add("in-view")},{threshold:[1]});setTimeout(function(){Array.prototype.forEach.call(document.querySelectorAll(".viewBox"),function(a,b){inView.observe(a)})},500)</script> <script src="https://www.compbio.com/js/jquery-3.4.1.min.js?v=1712159756" ></script> <script src="https://www.compbio.com/js/scripts.bundle.min.js?v=1712159769" defer></script> <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-NNJL9C4');</script>  </head> <body class="page-oncolytic-viral-vaccine temp-interior-sidebar spring" style="--mainColor: #; --subColor: #;">  <noscript><iframe src='https://www.googletagmanager.com/ns.html?id=GTM-NNJL9C4' height='0' width='0' style='display:none;visibility:hidden'></iframe></noscript>  <div id="page" class="hfeed site"> <a class="skip-link screen-reader-text" href="#content">Skip to content</a> <header id="masthead" class="site-header row"> <div class="row"> <div class="site-branding small-6 medium-3 columns"> <a href="https://www.compbio.com/" rel="home"> <img src="https://www.genesisglobalgrp.com/mods/images/logo_cbi_tag.png" alt="Comparative Biosciences, Inc." /> </a> <div id="gbg_logos"> <a href="http://www.genesisbiotechgroup.com"> <img src="https://www.genesisglobalgrp.com/mods/images/logo_ggg_member.png" alt="A Member of the Genesis Global Group"> </a> </div> </div> <a class="gd3-logo" href="http://gd3services.com"> <img src="https://www.genesisglobalgrp.com/mods/images/logo_gd3.png" alt="GD3 Services"> </a> <div class="small-6 medium-9 columns head-right"> <div class="scorr-mobile-menu-btn"> Menu <span class="search-icon"><i class="fa fa-bars"></i></span> </div> <nav id="top-navigation" class="navigation-section top-navigation"> <div class="menu-top-container"> <ul id="top-menu" class="menu"> <li id="menu-item-21" class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item current_page_item menu-item-home menu-item-21"><a href="https://www.compbio.com" aria-current="page">home</a></li> <li id="menu-item-5313" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-5313"><a target="_blank" rel="noopener" href="https://us232.dayforcehcm.com/CandidatePortal/en-US/ggg/SITE/CBICareerSite">careers</a></li> <li id="menu-item-2147" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2147"><a href="https://www.compbio.com/site-index/">site index</a></li> <li id="menu-item-710" class="menu-item menu-item-type-post_type menu-item-object-post menu-item-710"><a href="https://www.compbio.com/blog/privacy-policy/">privacy policy</a></li> <li id="menu-item-711" class="menu-item menu-item-type-post_type menu-item-object-post menu-item-711"><a href="https://www.compbio.com/blog/legal-notice/">legal notice</a></li> <li id="menu-item-2993" class="search-link menu-item menu-item-type-custom menu-item-object-custom menu-item-2993"><a href="#">Search <i></i></a></li> </ul> </div> </nav> <nav id="site-navigation" class="navigation-section main-navigation"> <button class="menu-toggle" aria-controls="primary-menu" aria-expanded="false">Primary Menu</button> <div class="menu-main-container"> <ul> <li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-ancestor current-menu-parent current_page_parent current_page_ancestor menu-item-has-children menu-item-2345"><a href="https://www.compbio.com/about-cbi/">About CBI</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-1948 current_page_item menu-item-1973"><a href="https://www.compbio.com/about-cbi/core-management-team/" aria-current="page">Core Management Team</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1972"><a href="https://www.compbio.com/about-cbi/scientific-advisors/">Scientific Advisers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2163"><a href="https://www.compbio.com/about-cbi/collaborations/">Collaborations</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1971"><a href="https://www.compbio.com/about-cbi/why-cbitestimonials/">Why CBI</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1970"><a href="https://www.compbio.com/about-cbi/careers/">Careers</a></li> </ul> </li><li><a href="https://www.compbio.com/therapeutic-areas/">Therapeutic Areas</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/therapeutic-areas/">Therapeutic Areas Overview</a></li> <li><a href="https://www.compbio.com/blog/rolly/">Surgical Modeling</a></li> <li><a href="https://www.compbio.com/blog/hypertrophic-scar-formation-in-rabbits/">Hypertrophic Scar Formation in Rabbits</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/dermatology/">Dermatology</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/therapeutic-areas/dermatology/dermal-efficacy-models/">Dermal Efficacy & Models</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/therapeutic-areas/dermatology/wound-healing-models/">Wound Healing Models</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/dermatology/dermal-burn-modeling/">Dermal Burn Modeling</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/inflammation/dermatologic-inflammation/">Dermatologic Inflammation</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/dermatology/delayed-type-hypersensitivity-dth-studies/">Delayed Type Hypersensitivity (DTH) Studies</a></li> </ul> </li> <li><a href="https://www.compbio.com/therapeutic-areas/dermatology/dermal-pharmacokinetics/">Pharmacokinetics</a></li> <li><a href="https://www.compbio.com/services/toxicology/dermal-toxicology/dermal-toxicology/">Dermal Toxicology</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/imiquimod-psoriasis/">Dermal Immune Mediated Disease</a></li> <li><a href="https://www.compbio.com/blog/murine-atopic-dermatitis-model/">Murine Atopic Dermatitis Model</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/">Ophthalmology</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/therapeutic-areas/ocular-efficacy-model/">Ocular Models of Pharmacology and Efficacy</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/neovascular-vascular-models/">Preclinical Ocular Efficacy</a></li> </ul> </li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/ocular-pharmacokinetics/">Pharmacokinetics</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/toxicology/">Ocular Toxicology</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/optical-coherence-tomography/">Optical Coherence Tomography (OCT Video)</a></li> </ul> </li> <li><a href="https://www.compbio.com/therapeutic-areas/cardiovascular/cardiovascular-efficacy-models/">Cardiovascular</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/therapeutic-areas/cardiovascular/cardiovascular-efficacy-models/">Cardiovascular Efficacy and Models</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/cardiovascular/therapeutic-hyperoxia-injury-models/">Hyperoxia Injury Models</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/cardiovascular/atherosclerosis/">Atherosclerosis</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/carotid-artery-repair/">Carotid Artery Repair</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/oncology/">Oncology</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/inflammation/">Inflammation</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/blog/1-dermal-immune-mediated-disease/">Dermal Immune Mediated Disease</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/inflammation/immune-mediated/">Immune-Mediated Studies</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/cardiovascular/therapeutic-hyperoxia-injury-models/">Hyperoxia Injury Models</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/inflammation/diabetic-models/">Diabetic and Metabolic Models</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/inflammation/dermatologic-inflammation/">Dermatologic Inflammation</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/inflammation/arthritis/">Arthritis</a></li> </ul> </li> <li><a href="https://www.compbio.com/therapeutic-areas/fibrotic-disease/">Fibrotic Disease</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/anti-infective/">Anti-infective Models</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/otic-study/">Ototoxicity and Auditory Studies</a></li> </ul> </li><li> <a href="https://www.compbio.com/services/toxicology/">Services</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/services/toxicology/">Toxicology in Preclinical Studies</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/toxicology-in-rodents/">TOXICOLOGY In Rodents</a></li> <li><a href="https://www.compbio.com/blog/oncolytic-viral-vaccine/">Oncolytic Viral Vaccine</a></li> <li><a href="https://www.compbio.com/services/toxicology/dermal-toxicology/dermal-toxicology/">Dermal Toxicology</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/toxicology/">Ocular Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/regulatory-toxicology/">Regulatory Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/discovery-toxicology/">Discovery Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/investigative-custom-toxicology/">Investigative Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/stem-cell-toxicology/">Stem Cell Toxicology</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/test-burn/">Dermal Burn Modeling</a></li> <li><a href="https://www.compbio.com/services/pharmacokinetics/">Pharmacokinetics</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/services/pharmacokinetics/preclinical-pharmacokinetics/">Preclinical Pharmacokinetics</a></li> <li><a href="https://www.compbio.com/services/pharmacokinetics/">Dermal Pharmacokinetics</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/ocular-pharmacokinetics/">Ocular Pharmacokinetics</a></li> </ul> </li> <li><a href="https://www.compbio.com/services/histopathology/">Histopathology</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/services/histopathology/regulatory-pathology-studies/">Research and Regulatory Pathology Studies</a></li> <li><a href="https://www.compbio.com/services/histopathology/immunohistochemistry/">Immunohistochemistry</a></li> <li><a href="https://www.compbio.com/services/histopathology/histopathology-special-stains/">Histopathology and Special Stains</a></li> <li><a href="https://www.compbio.com/services/histopathology/in-situ-hybridization/"><em>In Situ</em> Hybridization</a></li> <li><a href="https://www.compbio.com/services/histopathology/tissue-cross-reactivity-studies/">Tissue Cross-Reactivity Studies</a></li> <li><a href="https://www.compbio.com/services/histopathology/histomorphometry/">Histomorphometry and Digital Slide Analysis</a></li> <li><a href="https://www.compbio.com/services/histopathology/specialized-histology/">Specialized Histology</a></li> <li><a href="https://www.compbio.com/services/histopathology/devices-plastics-ground-sections/">Devices, Plastics and Ground Section Histology</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/t-cell-receptor-science-studies-and-services/">The Power of the TCR2</a></li> <li><a href="https://www.compbio.com/blog/biocompatibility-and-devices-research-at-comparative-biosciences-inc/">Biocompatibility and Devices</a></li> <li><a href="https://www.compbio.com/services/toxicology/stem-cell-toxicology">Stem Cell Research</a></li> <li><a href="https://www.compbio.com/services/specialized-surgical-pharmacology/">Specialized Surgical Pharmacology</a></li> <li><a href="https://www.compbio.com/services/veterinary-pharmacology/">Veterinary Pharmacology</a></li> <li><a href="https://www.compbio.com/blog/cannabis-pharmacology/">Cannabis Pharmacology</a></li> <li><a href="https://www.compbio.com/blog/cns-pharmacology/">Specialized CNS: Pharmacology and Surgery</a></li> <li><a href="https://www.compbio.com/pompe-disease/">Pompe Disease</a></li> <li><a href="https://www.compbio.com/intraocular-lens-implantation/">Intraocular Lens Implantation (video)</a></li> <li> <a>Pulmonary</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/blog/model-of-murine-pulmonary-aspergillosis/">Model of Murine Pulmonary Aspergillosis</a></li> <li><a href="https://www.compbio.com/blog/murine-hypersensitivity-pneumonitis-farmers-lung/">Model of Murine Hypersensitivity Pneumonitis</a></li> <li><a href="https://www.compbio.com/blog/nasal-aspergillosis-in-rabbits-2propionibacterium-acnes-induced-hypersensitivity/">Murine Model of Pulmonary Fibrosis and Chronic Inflammation</a></li> <li><a href="https://www.compbio.com/pulmonary/nasal-aspergillosis/">Model Of Nasal Aspergillosis In Rabbits</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/bladder-cancer/">Bladder Cancer</a></li> <li><a href="https://www.compbio.com/blog/spinal-trauma-in-rodents/">Spinal Trauma In Rodents</a></li> <li><a href="https://www.compbio.com/subcutaneous-implants-video/">Subcutaneous Implants + Video</a></li> </ul> </li> <li><a href="https://www.compbio.com/resources/" aria-current="page">Resources</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5522"><a href="https://www.compbio.com/powerpoint-presentations/">PowerPoint Presentations</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2635"><a href="https://www.compbio.com/our-blog/">Blog</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-2341"><a href="https://www.youtube.com/watch?v=l4pamRdMw2w">CBI Videos</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4653"><a href="https://www.compbio.com/coronavirus-diseaseimiquimod-psoriasis/">CBI Virtual Tour Video – 2021</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5344"><a href="https://www.compbio.com/subcutaneous-implant-procedure-2/">Subcutaneous Implant Procedure – Video</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2102"><a href="https://www.compbio.com/coronavirus-diseaseimiquimod-psoriasis/https-www-compbio-com-blog-carotid-artery-repair/">Carotid Artery Video Procedures</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5303"><a href="https://www.compbio.com/intraocular-lens-implantation-2/">Intraocular Lens Implantation – Video</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4872"><a href="https://www.compbio.com/newsletters-2-2/">Newsletters</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4873"><a href="https://www.compbio.com/publications-2/">Publications & White Papers</a></li> </ul> </li> <li><a href="https://www.compbio.com/contact-us/">Contact Us</a></li> </ul> </div> </nav> </div> </div> </header> <div id="content" class="site-content row"> <div id="page-head"> <header class="entry-header"> <div class="header-bar"></div> </header> </div> <div id="content-contain" class="row"> <div id="secondary" class="widget-area medium-3 columns" role="complementary"> <div class="secondary-content"> <span id="root-id" style="display:none;">2516</span> <div class="menu-main-container"> <ul id="menu-main" class="menu"> <li> <a href="https://www.compbio.com/services/toxicology/">Services</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/services/toxicology/">Toxicology in Preclinical Studies</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/toxicology-in-rodents/">TOXICOLOGY In Rodents</a></li> <li><a href="https://www.compbio.com/blog/oncolytic-viral-vaccine/">Oncolytic Viral Vaccine</a></li> <li><a href="https://www.compbio.com/services/toxicology/dermal-toxicology/dermal-toxicology/">Dermal Toxicology</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/toxicology/">Ocular Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/regulatory-toxicology/">Regulatory Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/discovery-toxicology/">Discovery Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/investigative-custom-toxicology/">Investigative Toxicology</a></li> <li><a href="https://www.compbio.com/services/toxicology/stem-cell-toxicology/">Stem Cell Toxicology</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/test-burn/">Dermal Burn Modeling</a></li> <li><a href="https://www.compbio.com/services/pharmacokinetics/">Pharmacokinetics</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/services/pharmacokinetics/preclinical-pharmacokinetics/">Preclinical Pharmacokinetics</a></li> <li><a href="https://www.compbio.com/services/pharmacokinetics/">Dermal Pharmacokinetics</a></li> <li><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/ocular-pharmacokinetics/">Ocular Pharmacokinetics</a></li> </ul> </li> <li><a href="https://www.compbio.com/services/histopathology/">Histopathology</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/services/histopathology/regulatory-pathology-studies/">Research and Regulatory Pathology Studies</a></li> <li><a href="https://www.compbio.com/services/histopathology/immunohistochemistry/">Immunohistochemistry</a></li> <li><a href="https://www.compbio.com/services/histopathology/histopathology-special-stains/">Histopathology and Special Stains</a></li> <li><a href="https://www.compbio.com/services/histopathology/in-situ-hybridization/"><em>In Situ</em> Hybridization</a></li> <li><a href="https://www.compbio.com/services/histopathology/tissue-cross-reactivity-studies/">Tissue Cross-Reactivity Studies</a></li> <li><a href="https://www.compbio.com/services/histopathology/histomorphometry/">Histomorphometry and Digital Slide Analysis</a></li> <li><a href="https://www.compbio.com/services/histopathology/specialized-histology/">Specialized Histology</a></li> <li><a href="https://www.compbio.com/services/histopathology/devices-plastics-ground-sections/">Devices, Plastics and Ground Section Histology</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/t-cell-receptor-science-studies-and-services/">The Power of the TCR2</a></li> <li><a href="https://www.compbio.com/blog/biocompatibility-and-devices-research-at-comparative-biosciences-inc/">Biocompatibility and Devices</a></li> <li><a href="https://www.compbio.com/services/toxicology/stem-cell-toxicology">Stem Cell Research</a></li> <li><a href="https://www.compbio.com/services/specialized-surgical-pharmacology/">Specialized Surgical Pharmacology</a></li> <li><a href="https://www.compbio.com/services/veterinary-pharmacology/">Veterinary Pharmacology</a></li> <li><a href="https://www.compbio.com/blog/cannabis-pharmacology/">Cannabis Pharmacology</a></li> <li><a href="https://www.compbio.com/blog/cns-pharmacology/">Specialized CNS: Pharmacology and Surgery</a></li> <li><a href="https://www.compbio.com/pompe-disease/">Pompe Disease</a></li> <li><a href="https://www.compbio.com/intraocular-lens-implantation/">Intraocular Lens Implantation (video)</a></li> <li> <a>Pulmonary</a> <ul class="sub-menu"> <li><a href="https://www.compbio.com/blog/model-of-murine-pulmonary-aspergillosis/">Model of Murine Pulmonary Aspergillosis</a></li> <li><a href="https://www.compbio.com/blog/murine-hypersensitivity-pneumonitis-farmers-lung/">Model of Murine Hypersensitivity Pneumonitis</a></li> <li><a href="https://www.compbio.com/blog/nasal-aspergillosis-in-rabbits-2propionibacterium-acnes-induced-hypersensitivity/">Murine Model of Pulmonary Fibrosis and Chronic Inflammation</a></li> <li><a href="https://www.compbio.com/pulmonary/nasal-aspergillosis/">Model Of Nasal Aspergillosis In Rabbits</a></li> </ul> </li> <li><a href="https://www.compbio.com/blog/bladder-cancer/">Bladder Cancer</a></li> <li><a href="https://www.compbio.com/blog/spinal-trauma-in-rodents/">Spinal Trauma In Rodents</a></li> <li><a href="https://www.compbio.com/subcutaneous-implants-video/">Subcutaneous Implants + Video</a></li> </ul> </li> </ul> </div> </div> </div> <div id="primary" class="content-area medium-9 columns"> <div class="header-title"> <h1 class="entry-title">Oncolytic Viral Vaccine</h1> </div> <main id="main" class="site-main" role="main"> <article id="post-4565" class="post-4565 post type-post status-publish format-standard hentry category-general"> <div id="breadcrumb"> <div id="crumbs"> <span class="crumb"><a href="https://www.compbio.com">Home</a></span> <i class="fa fa-angle-right"></i> <span class="crumb"><a href="https://www.compbio.com/general/">General</a></span> <i class="fa fa-angle-right"></i> <span class="current">Oncolytic Viral Vaccine</span> </div> </div> <div class="entry-content"> <div class="the-content-contain"> <div class="row builder-row content-row"> <div class="medium-12 columns"> <h2> <img class="alignleft wp-image-4606 " src="https://www.compbio.com/images/frontiers-in-immunology-tat-hiv-300x169.jpg?v=1712600971" alt="" width="435" height="245" srcset="https://www.compbio.com/images/frontiers-in-immunology-tat-hiv-300x169.jpg?v=1712600971 300w, https://www.compbio.com/images/frontiers-in-immunology-tat-hiv-768x432.jpg?v=1712600964 768w, https://www.compbio.com/images/frontiers-in-immunology-tat-hiv.jpg?v=1712600958 1000w" sizes="(max-width: 435px) 100vw, 435px"></h2> <h2> <img loading="lazy" class="alignleft wp-image-4570" src="https://www.compbio.com/images/CBI-Eblast-Oncolytic-Vaccine-header-300x250.jpg?v=1712601057" alt="" width="436" height="363" srcset="https://www.compbio.com/images/CBI-Eblast-Oncolytic-Vaccine-header-300x250.jpg?v=1712601057 300w, https://www.compbio.com/images/CBI-Eblast-Oncolytic-Vaccine-header-1024x853.jpg?v=1712601048 1024w, https://www.compbio.com/images/CBI-Eblast-Oncolytic-Vaccine-header-768x640.jpg?v=1712601043 768w, https://www.compbio.com/images/CBI-Eblast-Oncolytic-Vaccine-header-1536x1279.jpg?v=1712601038 1536w, https://www.compbio.com/images/CBI-Eblast-Oncolytic-Vaccine-header-2048x1706.jpg?v=1712601031 2048w" sizes="(max-width: 436px) 100vw, 436px"></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2></h2> <h2>Oncolytic Viral Vaccine Toxicology at CBI</h2> <p> </p> <p><strong>Introduction to Toxicology.</strong></p> <p>“Oncolytic viral therapy is a new promising strategy against cancer.<span class="Apple-converted-space"> </span>Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells,<span class="Apple-converted-space"> </span>leading to lysis of the tumor mass.”</p> <p><strong>Background.</strong></p> <p>Oncolytic viral vaccines represents a novel and exciting approach to the treatment of cancer. In 2015, the U.S. Food and Drug Administration approved the first oncolytic virus immunotherapy for the treatment of cancer — T-VEC for melanoma. There are now a number of exciting new products in development. CBI has conducted a number of toxicology programs with oncolytic viral vaccines for our clients.</p> <p>An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumor. Oncolytic virotherapy has shown impressive results in preclinical studies and first promising therapeutic outcomes in clinical trials as well. Since viruses are known for a long time as excellent vaccination agents, oncolytic viruses are now designed as novel anticancer agents combining the aspect of lysis-dependent cytoreductive activity with concomitant induction of antitumoral immune responses. Antitumoral immune activation by oncolytic virus infection of tumor tissue comprises both, immediate effects of innate immunity and also adaptive responses for long lasting antitumoral activity, which is regarded as the most prominent challenge in clinical oncology (Woller et al 2014).</p> <p><strong>Oncolytic Viral Vaccine Toxicology at CBI.</strong></p> <p>CBI specializes in customizing, designing and implementing GLP toxicology studies for regulatory submission as well as research and nonGLP studies with oncolytic vaccine products for our clients. Generally, these studies are conducted in immune-incompetent mice, both tumor bearing and non-tumor bearing. In addition to typical toxicology assessment, these programs often have unusual requirements with regard to routes of administration, types of tumors, sites for tumor implantation, and bioassays. The FDA has a number of unique and specialized requirements for these studies as well. The FDA is concerned about cardiac toxicity, hence the need for murine troponins, as well as a large battery of cytokines and mediators. Immunohistochemistry of the tumor and target organs is often needed. Assays may include qPCR, PRNT, and ADA bioassays. Customized assays may be required based upon the individual study requirements.</p> <p>• Comparative Biosciences, Inc. has conducted a number of these toxicology programs with oncolytic viral vaccines for our clients. Since this therapy is still so new, we are excited that CBI is at the<span class="Apple-converted-space"> </span>forefront of these new products and toxicology testings.</p> <p> </p> <h2>Oncolytic Viral Vaccine Toxicology Program</h2> <p> <img loading="lazy" class="wp-image-4599 alignnone" src="https://www.compbio.com/images/CBI-Oncolytic-Chart-1-300x160.jpg?v=1712601346" alt="" width="696" height="371" srcset="https://www.compbio.com/images/CBI-Oncolytic-Chart-1-300x160.jpg?v=1712601346 300w, https://www.compbio.com/images/CBI-Oncolytic-Chart-1-1024x545.jpg?v=1712601376 1024w, https://www.compbio.com/images/CBI-Oncolytic-Chart-1-768x409.jpg?v=1712601384 768w, https://www.compbio.com/images/CBI-Oncolytic-Chart-1-1536x817.jpg?v=1712601417 1536w, https://www.compbio.com/images/CBI-Oncolytic-Chart-1-2048x1089.jpg?v=1712601391 2048w" sizes="(max-width: 696px) 100vw, 696px"> <img loading="lazy" class=" wp-image-4602 aligncenter" src="https://www.compbio.com/images/cute-mouse-darwin-wiggett-300x207.jpg?v=1712601460" alt="" width="233" height="161" srcset="https://www.compbio.com/images/cute-mouse-darwin-wiggett-300x207.jpg?v=1712601460 300w, https://www.compbio.com/images/cute-mouse-darwin-wiggett-768x529.jpg?v=1712601448 768w, https://www.compbio.com/images/cute-mouse-darwin-wiggett.jpg?v=1712601443 900w" sizes="(max-width: 233px) 100vw, 233px"><strong>Vaccines play a vital role in preventive medicine in Pre-clinical testing. Vaccine safety is our prime concern at Comparative Biosciences, Inc.</strong> </p> <p> </p> <p><a href="https://www.compbio.com/contact-us/" target="_blank" rel="noopener noreferrer">NEED TO CONDUCT A STUDY?   •   Telephone 408-738-9266</a></p> <div>Contact: Jonathan A. Geller, MS</div> <div>Business Development Manager</div> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p><strong>Keywords:</strong> oncolytic virus, immunotherapy, host immune response, tumor immunity, cancer-related inflammation, virotherapy, adenovirus, vaccinia virus</p> <p>Immunocompetent mice       Immunocompromised mice       Tumor and nontumor bearing mice</p> <p>Clinical Observations             Body Weights                                 Food Consumption</p> <p>Necropsy Organ Weights Clinical Pathology</p> <p>Histopathology QAU Report Preparation and Archiving</p> <p>Special Bioassays Anti-drug Antibody Quantification Plaque Reduction Neutralization Test qPCR Tissue and matrix validation HPLC and LCMS</p> <p>Special and Customized Tests</p> <p>Troponins for cardiotoxicity Immunohistochemistry Immunofluorescence Cytokine mediator panels Histomorphometry Cell sorting</p> <p><a href="https://www.creative-biolabs.com/oncolytic-virus/">https://www.creative-biolabs.com/oncolytic-virus/</a></p> </div> </div> </div> </div> </article> </main> </div> </div> <div class="call-out"> <h3 class="content-left"><span class="line-one">Have a question</span> <span class="line-two">or need a quote?</span></h3> <svg version="1.1" id="Layer_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 100 85" style="enable-background:new 0 0 100 85;" xml:space="preserve"> <style type="text/css"> .st0{fill:#FFFFFF;} </style> <g> <path class="st0" d="M64.3,0.5H16c-8.8,0-16,7.2-16,16V44c0,8.4,6.6,15.4,14.9,16l-3.7,17.4L31.6,60h8.8V43.9 c0-8.7,7.1-15.8,15.8-15.8h24.2V16.5C80.3,7.7,73.1,0.5,64.3,0.5z"/> <path class="st0" d="M89.1,33h-33c-6,0-10.9,4.9-10.9,10.9v18.8c0,6,4.9,10.9,10.9,10.9h22.4l13.9,11.8l-2.5-11.9 c5.7-0.4,10.2-5.1,10.2-10.9V44C100,38,95.1,33,89.1,33z M85.5,49.3c2.2,0,4,1.8,4,4.1c0,2.2-1.8,4.1-4,4.1s-4-1.8-4-4.1 C81.5,51.1,83.3,49.3,85.5,49.3z M59.6,57.4c-2.2,0-4-1.8-4-4.1c0-2.2,1.8-4.1,4-4.1c2.2,0,4,1.8,4,4.1 C63.7,55.6,61.9,57.4,59.6,57.4z M68.5,53.4c0-2.2,1.8-4.1,4-4.1s4,1.8,4,4.1c0,2.2-1.8,4.1-4,4.1S68.5,55.6,68.5,53.4z"/> </g> </svg> <h3 class="content-right"><span>We can help!</span> <a href="https://www.compbio.com/contact-us/"><span class="cta-btn">Contact us</span></a></h3> </div> </div> </div> <footer id="colophon" class="site-footer row"> <div class="site-info medium-12 columns"> Comparative Biosciences, Inc. · <strong>Phone: 888-994-4879</strong><br> Copyright 2024 Comparative Biosciences, Inc. All rights reserved. </div> </footer> <div id="search-form" class="lightbox"> <div class="close"></div> <div id="search-form-contain" class="lightbox-contain"> <div class="search-contain row"> <div class="search-form small-11 columns"> <form action="https://www.compbio.com/search_main" method="post" id="main-searchform"> <input type="text" name="s" id="search" placeholder="Search Our Site" value="" /> </form> </div> <div class="small-1 columns"> <span class="main-search-submit"><i class="fa fa-search"></i></span> </div> </div> </div> </div> <div id="mobile-menu" class="lightbox"> <div class="close"></div> <div id="mobile-menu-contain" class="lightbox-contain"> <div class="menu-main-container"><ul id="mobile-menu-list" class="menu"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2345"><a href="https://www.compbio.com/preclinical-studies/">About CBI</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2344"><a href="https://www.compbio.com/preclinical-studies/">Company</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1973"><a href="https://www.compbio.com/core-management-team/">Core Management Team</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1972"><a href="https://www.compbio.com/scientific-advisors/">Scientific Advisers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2163"><a href="https://www.compbio.com/collaborations/">Collaborations</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1971"><a href="https://www.compbio.com/why-cbitestimonials/">Why CBI</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1970"><a href="https://www.compbio.com/careers/">Careers</a></li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-2516"><a href="https://www.compbio.com/therapeutic-areas/">Therapeutic Areas</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2863"><a href="https://www.compbio.com/therapeutic-areas/">Therapeutic Areas Overview</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5197"><a href="https://www.compbio.com/rolly/">Surgical Modeling</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5543"><a href="https://www.compbio.com/hypertrophic-scar-formation-in-rabbits/">Hypertrophic Scar Formation in Rabbits</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2008"><a href="https://www.compbio.com/dermatology/">Dermatology</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2007"><a href="https://www.compbio.com/dermal-efficacy-models/">Dermal Efficacy & Models</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3005"><a href="https://www.compbio.com/wound-healing-models/">Wound Healing Models</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2982"><a href="https://www.compbio.com/dermal-burn-modeling/">Dermal Burn Modeling</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3034"><a href="https://www.compbio.com/dermatologic-inflammation/">Dermatologic Inflammation</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3033"><a href="https://www.compbio.com/delayed-type-hypersensitivity-dth-studies/">Delayed Type Hypersensitivity (DTH) Studies</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2016"><a href="https://www.compbio.com/dermal-pharmacokinetics/">Pharmacokinetics</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2018"><a href="https://www.compbio.com/dermal-toxicology/">Dermal Toxicology</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4899"><a href="https://www.compbio.com/imiquimod-psoriasis/">Dermal Immune Mediated Disease</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5583"><a href="https://www.compbio.com/murine-atopic-dermatitis-model/">Murine Atopic Dermatitis Model</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2014"><a href="https://www.compbio.com/ophthalmology/">Ophthalmology</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2012"><a href="https://www.compbio.com/ocular-efficacy-model/">Ocular Models of Pharmacology and Efficacy</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2845"><a href="https://www.compbio.com/neovascular-vascular-models/">Preclinical Ocular Efficacy</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2017"><a href="https://www.compbio.com/ocular-pharmacokinetics/">Pharmacokinetics</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2243"><a href="https://www.compbio.com/toxicology/">Ocular Toxicology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3050"><a href="https://www.compbio.com/therapeutic-areas/ophthalmology/optical-coherence-tomography/">Optical Coherence Tomography (OCT Video)</a></li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-2247"><a href="https://www.compbio.com/cardiovascular-efficacy-models/">Cardiovascular</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2006"><a href="https://www.compbio.com/cardiovascular-efficacy-models/">Cardiovascular Efficacy and Models</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2855"><a href="https://www.compbio.com/therapeutic-hyperoxia-injury-models/">Hyperoxia Injury Models</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2004"><a href="https://www.compbio.com/atherosclerosis/">Atherosclerosis</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5032"><a href="https://www.compbio.com/carotid-artery-repair/">Carotid Artery Repair</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2013"><a href="https://www.compbio.com/therapeutic-areas/oncology/">Oncology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2010"><a href="https://www.compbio.com/inflammation/">Inflammation</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4940"><a href="https://www.compbio.com/1-dermal-immune-mediated-disease/">Dermal Immune Mediated Disease</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3691"><a href="https://www.compbio.com/immune-mediated/">Immune-Mediated Studies</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2936"><a href="https://www.compbio.com/therapeutic-areas/cardiovascular/therapeutic-hyperoxia-injury-models/">Hyperoxia Injury Models</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2968"><a href="https://www.compbio.com/diabetic-models/">Diabetic and Metabolic Models</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2934"><a href="https://www.compbio.com/dermatologic-inflammation/">Dermatologic Inflammation</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2003"><a href="https://www.compbio.com/arthritis/">Arthritis</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2009"><a href="https://www.compbio.com/fibrotic-disease/">Fibrotic Disease</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2002"><a href="https://www.compbio.com/anti-infective/">Anti-infective Models</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2015"><a href="https://www.compbio.com/otic-study/">Ototoxicity and Auditory Studies</a></li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-2710"><a href="/toxicology/">Services</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2285"><a href="https://www.compbio.com/toxicology/">Toxicology in Preclinical Studies</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5384"><a href="https://www.compbio.com/toxicology-in-rodents/">TOXICOLOGY In Rodents</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4569"><a href="https://www.compbio.com/oncolytic-viral-vaccine/">Oncolytic Viral Vaccine</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2288"><a href="https://www.compbio.com/dermal-toxicology/">Dermal Toxicology</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2289"><a href="/toxicology">Ocular Toxicology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2048"><a href="https://www.compbio.com/regulatory-toxicology/">Regulatory Toxicology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2047"><a href="https://www.compbio.com/discovery-toxicology/">Discovery Toxicology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2046"><a href="https://www.compbio.com/investigative-custom-toxicology/">Investigative Toxicology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2045"><a href="https://www.compbio.com/stem-cell-toxicology/">Stem Cell Toxicology</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5425"><a href="https://www.compbio.com/test-burn/">Dermal Burn Modeling</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2057"><a href="https://www.compbio.com/pharmacokinetics/">Pharmacokinetics</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2059"><a href="https://www.compbio.com/preclinical-pharmacokinetics/">Preclinical Pharmacokinetics</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2303"><a href="https://www.compbio.com/pharmacokinetics/">Dermal Pharmacokinetics</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2304"><a href="/ocular-pharmacokinetics/">Ocular Pharmacokinetics</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-2084"><a href="https://www.compbio.com/histopathology/">Histopathology</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2090"><a href="https://www.compbio.com/regulatory-pathology-studies/">Research and Regulatory Pathology Studies</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2769"><a href="https://www.compbio.com/immunohistochemistry/">Immunohistochemistry</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2089"><a href="https://www.compbio.com/histopathology-special-stains/">Histopathology and Special Stains</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2088"><a href="https://www.compbio.com/in-situ-hybridization/"><em>In Situ</em> Hybridization</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2087"><a href="https://www.compbio.com/tissue-cross-reactivity-studies/">Tissue Cross-Reactivity Studies</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2086"><a href="https://www.compbio.com/histomorphometry/">Histomorphometry and Digital Slide Analysis</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2085"><a href="https://www.compbio.com/specialized-histology/">Specialized Histology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3301"><a href="https://www.compbio.com/devices-plastics-ground-sections/">Devices, Plastics and Ground Section Histology</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5476"><a href="https://www.compbio.com/t-cell-receptor-science-studies-and-services/">The Power of the TCR2</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5440"><a href="https://www.compbio.com/biocompatibility-and-devices-research-at-comparative-biosciences-inc/">Biocompatibility and Devices</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2334"><a href="/stem-cell-toxicology">Stem Cell Research</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2092"><a href="https://www.compbio.com/specialized-surgical-pharmacology/">Specialized Surgical Pharmacology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3077"><a href="https://www.compbio.com/veterinary-pharmacology/">Veterinary Pharmacology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-3787"><a href="https://www.compbio.com/cannabis-pharmacology/">Cannabis Pharmacology</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-3884"><a href="https://www.compbio.com/cns-pharmacology/">Specialized CNS: Pharmacology and Surgery</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4421"><a href="https://www.compbio.com/pompe-disease/">Pompe Disease</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4468"><a href="https://www.compbio.com/intraocular-lens-implantation/">Intraocular Lens Implantation (video)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-4034"><a>Pulmonary</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4027"><a href="https://www.compbio.com/model-of-murine-pulmonary-aspergillosis/">Model of Murine Pulmonary Aspergillosis</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4028"><a href="https://www.compbio.com/murine-hypersensitivity-pneumonitis-farmers-lung/">Model of Murine Hypersensitivity Pneumonitis</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4029"><a href="https://www.compbio.com/nasal-aspergillosis-in-rabbits-2propionibacterium-acnes-induced-hypersensitivity/">Murine Model of Pulmonary Fibrosis and Chronic Inflammation</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4122"><a href="https://www.compbio.com/nasal-aspergillosis/">Model Of Nasal Aspergillosis In Rabbits</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-4963"><a href="https://www.compbio.com/bladder-cancer/">Bladder Cancer</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-5168"><a href="https://www.compbio.com/spinal-trauma-in-rodents/">Spinal Trauma In Rodents</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5370"><a href="https://www.compbio.com/subcutaneous-implants-video/">Subcutaneous Implants + Video</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-4874"><a href="https://www.compbio.com/resources/">Resources</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5522"><a href="https://www.compbio.com/powerpoint-presentations/">PowerPoint Presentations</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-2635"><a target="_blank" rel="noopener" href="https://www.compbio.com/our-blog/">Blog</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-2341"><a href="https://www.youtube.com/watch?v=l4pamRdMw2w">CBI Videos</a> <ul class="sub-menu"> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4653"><a href="https://www.compbio.com/coronavirus-diseaseimiquimod-psoriasis/">CBI Virtual Tour Video – 2021</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5344"><a href="https://www.compbio.com/subcutaneous-implant-procedure-2/">Subcutaneous Implant Procedure – Video</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2102"><a href="https://www.compbio.com/coronavirus-diseaseimiquimod-psoriasis/https-www-compbio-com-blog-carotid-artery-repair/">Carotid Artery Video Procedures</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-5303"><a href="https://www.compbio.com/intraocular-lens-implantation-2/">Intraocular Lens Implantation – Video</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4872"><a href="https://www.compbio.com/newsletters-2-2/">Newsletters</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-4873"><a href="https://www.compbio.com/publications-2/">Publications & White Papers</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1969"><a href="https://www.compbio.com/contact-us/">Contact Us</a></li> </ul></div> <div class="menu-top-container"><ul id="secondary-mobile-menu-list" class="menu"><li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item current_page_item menu-item-home menu-item-21"><a href="https://www.compbio.com" aria-current="page">home</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-5313"><a target="_blank" rel="noopener" href="https://us232.dayforcehcm.com/CandidatePortal/en-US/ggg/SITE/CBICareerSite">careers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-2147"><a href="https://www.compbio.com/site-index/">site index</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-710"><a href="https://www.compbio.com/privacy-policy/">privacy policy</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-post menu-item-711"><a href="https://www.compbio.com/legal-notice/">legal notice</a></li> <li class="search-link menu-item menu-item-type-custom menu-item-object-custom menu-item-2993"><a href="#">Search <i></i></a></li> </ul></div> </div> </div> <div id="video-box" class="lightbox"> <div class="close"><span class="x1"></span><span class="x2"></span></div> <div id="player_contain"> </div> </div> <div id="share-box" class="lightbox"> <div class="close"><span class="x1"></span><span class="x2"></span></div> <div class="row"> <div class="medium-6 columns small-centered"> <h3>Share: Comparative Biosciences, Inc.</h3> <div class="share-icons"> <a href="http://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fwww.compbio.com" target="_blank"><i class="fa fa-linkedin"></i></a> <a href="http://twitter.com/share?url=https%3A%2F%2Fwww.compbio.com" target="_blank"><i class="fa fa-twitter"></i></a> <a href="http://www.facebook.com/sharer.php?u=https%3A%2F%2Fwww.compbio.com" target="_blank"><i class="fa fa-facebook"></i></a> <a href="mailto:?subject=Comparative%20Biosciences%2C%20Inc.%3A%20Comparative%20Biosciences%2C%20Inc.&body=https%3A%2F%2Fwww.compbio.com" target="_blank"><i class="fa fa-envelope"></i></a> </div> <div id="link_sharer" class="row"> <form> <div class="medium-10 columns medium-centered"> <input type="text" class="share_link" value="https://www.compbio.com" onclick="this.setSelectionRange(0, this.value.length)" readonly=""> </div> </form> </div> </div> </div> </div> </body> </html>