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P19652 | SWISS-MODEL Repository
<!DOCTYPE html><html lang="en"><head><title>P19652 | SWISS-MODEL Repository</title><meta name="google-site-verification" content="b9is0bMUORIVsNjIJ3zigkFHMlGrnRCa6VldJKH5crU" /><meta charset="utf-8"><!-- Matomo --><script> var _paq = window._paq = window._paq || []; /* tracker methods like "setCustomDimension" should be called before "trackPageView" */ _paq.push(['trackPageView']); _paq.push(['enableLinkTracking']); (function() { var u="https://matomo.sib.swiss/"; _paq.push(['setTrackerUrl', u+'matomo.php']); _paq.push(['setSiteId', '3']); var d=document, g=d.createElement('script'), s=d.getElementsByTagName('script')[0]; g.async=true; g.src=u+'matomo.js'; s.parentNode.insertBefore(g,s); })(); </script><!-- End Matomo Code --><meta name="viewport" content="width=device-width, initial-scale=1"><meta name="ROBOTS" content="ALL" /><meta name="theme-color" content="#e30613" /><meta name="description" content="SWISS-MODEL Repository entry for P19652 (A1AG2_HUMAN), Alpha-1-acid glycoprotein 2. 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margin-left:8px;" href="https://www.uniprot.org/uniprotkb/P19652/entry" target="_blank" title="Reviewed (Swiss-Prot)"><i style="font-size:1em" class="glyphicon glyphicon-star"></i> UniProtKB<i class="glyphicon glyphicon-new-window" style="opacity:0.5; font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a><a style="color:#333" href="https://www.ebi.ac.uk/interpro/protein/P19652" target="_blank">InterPro<i class="glyphicon glyphicon-new-window" style="opacity:0.5; font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a><a class="stringLink" stringId="9606.ENSP00000394936" style="color:#333" href="https://string-db.org/network/9606.ENSP00000394936" target="_blank">STRING<i class="glyphicon glyphicon-new-window" style="opacity:0.5; font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a><a class="btn btn-sm btn-primary" href="/interactive/?ac=P19652" target="_blank" title="Start a new project with this UniProtKB entry as the target sequence in your own SWISS-MODEL workspace." >Interactive Modelling</a></small></h4><div> 201 aa; <a style="color:#333" href="/repository/uniprot/P19652.fasta" target="_blank">Sequence (Fasta) <i class="glyphicon glyphicon-file icon-white"></i></a></div></div></div><div id="flex-panel-container"><div id="left-panel"><div id="mdlChartContainer"><div id="mdlChart_55949a5c7a109a30e366c0648063b5a0" style="width:100%;"></div><div id="sequenceStatus" style="width: 100%; height: 100%; position:absolute; background-color: #444; top:0; opacity:.5; color: white; display: none; align-items: center; justify-content: center; text-align: center; font-size:1.7em;"> Rendering slow - skipping non-selected models </div></div><!-- begin mod_status admin view --><div></div><!-- end mod_status_admin view --><!-- begin warning panel --><div><div class="alert alert-warning" role="alert"><p> It is possible new templates exist for this target since these models were created. </p><form class="text-center" method="POST" action="/repository/uniprot/P19652/update"><input type="hidden" name="csrfmiddlewaretoken" value="00yIsbgEeEWwbZLuPu1GLT0v8o4VeYHM0hZkHyAVNoEMV5uaC2WHUAtwIQJJSzma"><button type="submit" class="btn btn-sm btn-primary" title="The models were built before the latest SMTL update. It is possible that new templates exist, which could build a better model.">Rebuild Models</button></form></div></div><!-- end warning panel --><h4 id="availableStructures"><a style="color:#333;" href="#" onclick="$('#allmodels-panel').toggle();$(this).find('i').toggle();return false;">Available Structures <small><i class="glyphicon glyphicon-chevron-down" style="display:none"></i><i class="glyphicon glyphicon-chevron-up"></i></small></a></h4><!-- Start structure list panel --><div id="allmodels-panel"><div id="allmodelsDiv"><h4>5 Experimental Structures</h4><table style="margin:0px" class="table noborder tablesorter allStructuresList" ><thead><tr><th></th><th>Description</th><th>PDB ID</th><th>Oligo-state</th><th>Range</th><th>Seq id (%)</th><th>Ligands</th></tr></thead><tbody><tr id="cid_66ac13223ef836575739ad6f" class="selectedRow"><td rowspan="2" class="displayStructureWrapper"><label title="Select to display 3D structure"><input type="radio" name="displayStructure"/></label></td><td class="pdbDesc">Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex</td><td><div class="dropdown pdblinks"><a class="dropdown-toggle" data-toggle="dropdown">3apx</a><ul class="dropdown-menu pull-right"><li title="Protein Databank in Europe"><a href="https://www.ebi.ac.uk/pdbe/entry/pdb/3apx" target="_blank">PDBe</a></li><li title="Protein Databank in Knowledge Base"><a href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/3apx" target="_blank">PDBe-KB</a></li><li title="Protein Databank in Japan"><a href="https://pdbj.org/mine/summary/3apx" target="_blank">PDBj</a></li><li title="Protein Databank Summary"><a href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=3apx" target="_blank">PDBsum</a></li><li title="Research Collaboratory for Structural Bioinformatics Protein Data Bank"><a href="https://www.rcsb.org/structure/3apx" target="_blank">RCSB</a></li><li title="SWISS-MODEL Template Library"><a href="/templates/3apx" target="_blank">SMTL</a></li></ul></div></td><td>monomer</td><td nowrap="nowrap"><span style="display:none">19-196</span><div id="range_66ac13223ef836575739ad6f" seqLength="201" resFrom="19" resTo="196" title="Range: 19-196"></div></td><td>99.44</td><td>1×<span title="3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine">Z80;</span> 1×<span title="ACETIC ACID">ACY;</span></td></tr><tr id="cid_66ac13223ef836575739ad6f" class="tablesorter-childRow selectedRow"" ><td colspan="7"><div class="smtools" ><a href="/repository/66ac13223ef836575739ad6f.pdb" target="_blank" title="Download Coordinates PDB Format"> Download <i class="glyphicon glyphicon-download-alt"></i></a><div style="display:flex; align-items: center; "><label title="Add to Comparison List"> Compare <input type="checkbox" class="compareCheck" id="cmp_66ac13223ef836575739ad6f"></label></div><a class="assessLink" coord_id="66ac13223ef836575739ad6f" href="/assess" target="_blank" title="Structure Assessment">Structure Assessment<i class="glyphicon glyphicon-new-window" style="font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a></div></td></tr><tr id="cid_66abad1b3ef836575731c1e0" ><td rowspan="2" class="displayStructureWrapper"><label title="Select to display 3D structure"><input type="radio" name="displayStructure"/></label></td><td class="pdbDesc">Crystal structure of the A variant of human alpha1-acid glycoprotein</td><td><div class="dropdown pdblinks"><a class="dropdown-toggle" data-toggle="dropdown">3apu</a><ul class="dropdown-menu pull-right"><li title="Protein Databank in Europe"><a href="https://www.ebi.ac.uk/pdbe/entry/pdb/3apu" target="_blank">PDBe</a></li><li title="Protein Databank in Knowledge Base"><a href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/3apu" target="_blank">PDBe-KB</a></li><li title="Protein Databank in Japan"><a href="https://pdbj.org/mine/summary/3apu" target="_blank">PDBj</a></li><li title="Protein Databank Summary"><a href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=3apu" target="_blank">PDBsum</a></li><li title="Research Collaboratory for Structural Bioinformatics Protein Data Bank"><a href="https://www.rcsb.org/structure/3apu" target="_blank">RCSB</a></li><li title="SWISS-MODEL Template Library"><a href="/templates/3apu" target="_blank">SMTL</a></li></ul></div></td><td>monomer</td><td nowrap="nowrap"><span style="display:none">19-193</span><div id="range_66abad1b3ef836575731c1e0" seqLength="201" resFrom="19" resTo="193" title="Range: 19-193"></div></td><td>99.43</td><td>1×<span title="TETRAETHYLENE GLYCOL">PG4;</span></td></tr><tr id="cid_66abad1b3ef836575731c1e0" class="tablesorter-childRow" ><td colspan="7"><div class="smtools" ><a href="/repository/66abad1b3ef836575731c1e0.pdb" target="_blank" title="Download Coordinates PDB Format"> Download <i class="glyphicon glyphicon-download-alt"></i></a><div style="display:flex; align-items: center; "><label title="Add to Comparison List"> Compare <input type="checkbox" class="compareCheck" id="cmp_66abad1b3ef836575731c1e0"></label></div><a class="assessLink" coord_id="66abad1b3ef836575731c1e0" href="/assess" target="_blank" title="Structure Assessment">Structure Assessment<i class="glyphicon glyphicon-new-window" style="font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a></div></td></tr><tr id="cid_66abba0c3ef836575732c899" ><td rowspan="2" class="displayStructureWrapper"><label title="Select to display 3D structure"><input type="radio" name="displayStructure"/></label></td><td class="pdbDesc">Crystal structure of the A variant of human alpha1-acid glycoprotein and disopyramide complex</td><td><div class="dropdown pdblinks"><a class="dropdown-toggle" data-toggle="dropdown">3apw</a><ul class="dropdown-menu pull-right"><li title="Protein Databank in Europe"><a href="https://www.ebi.ac.uk/pdbe/entry/pdb/3apw" target="_blank">PDBe</a></li><li title="Protein Databank in Knowledge Base"><a href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/3apw" target="_blank">PDBe-KB</a></li><li title="Protein Databank in Japan"><a href="https://pdbj.org/mine/summary/3apw" target="_blank">PDBj</a></li><li title="Protein Databank Summary"><a href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=3apw" target="_blank">PDBsum</a></li><li title="Research Collaboratory for Structural Bioinformatics Protein Data Bank"><a href="https://www.rcsb.org/structure/3apw" target="_blank">RCSB</a></li><li title="SWISS-MODEL Template Library"><a href="/templates/3apw" target="_blank">SMTL</a></li></ul></div></td><td>monomer</td><td nowrap="nowrap"><span style="display:none">20-194</span><div id="range_66abba0c3ef836575732c899" seqLength="201" resFrom="20" resTo="194" title="Range: 20-194"></div></td><td>99.43</td><td>1×<span title="Disopyramide">DP0;</span></td></tr><tr id="cid_66abba0c3ef836575732c899" class="tablesorter-childRow" ><td colspan="7"><div class="smtools" ><a href="/repository/66abba0c3ef836575732c899.pdb" target="_blank" title="Download Coordinates PDB Format"> Download <i class="glyphicon glyphicon-download-alt"></i></a><div style="display:flex; align-items: center; "><label title="Add to Comparison List"> Compare <input type="checkbox" class="compareCheck" id="cmp_66abba0c3ef836575732c899"></label></div><a class="assessLink" coord_id="66abba0c3ef836575732c899" href="/assess" target="_blank" title="Structure Assessment">Structure Assessment<i class="glyphicon glyphicon-new-window" style="font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a></div></td></tr><tr id="cid_66ac1c7f3ef83657573a66a3" ><td rowspan="2" class="displayStructureWrapper"><label title="Select to display 3D structure"><input type="radio" name="displayStructure"/></label></td><td class="pdbDesc">High resolution structure of Alpha-1-acid glycoprotein bound to potent anti-tumour compound UCN-01</td><td><div class="dropdown pdblinks"><a class="dropdown-toggle" data-toggle="dropdown">7oub</a><ul class="dropdown-menu pull-right"><li title="Protein Databank in Europe"><a href="https://www.ebi.ac.uk/pdbe/entry/pdb/7oub" target="_blank">PDBe</a></li><li title="Protein Databank in Knowledge Base"><a href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/7oub" target="_blank">PDBe-KB</a></li><li title="Protein Databank in Japan"><a href="https://pdbj.org/mine/summary/7oub" target="_blank">PDBj</a></li><li title="Protein Databank Summary"><a href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=7oub" target="_blank">PDBsum</a></li><li title="Research Collaboratory for Structural Bioinformatics Protein Data Bank"><a href="https://www.rcsb.org/structure/7oub" target="_blank">RCSB</a></li><li title="SWISS-MODEL Template Library"><a href="/templates/7oub" target="_blank">SMTL</a></li></ul></div></td><td>monomer</td><td nowrap="nowrap"><span style="display:none">19-189</span><div id="range_66ac1c7f3ef83657573a66a3" seqLength="201" resFrom="19" resTo="189" title="Range: 19-189"></div></td><td>99.42</td><td>1×<span title="7-HYDROXYSTAUROSPORINE">UCN;</span></td></tr><tr id="cid_66ac1c7f3ef83657573a66a3" class="tablesorter-childRow" ><td colspan="7"><div class="smtools" ><a href="/repository/66ac1c7f3ef83657573a66a3.pdb" target="_blank" title="Download Coordinates PDB Format"> Download <i class="glyphicon glyphicon-download-alt"></i></a><div style="display:flex; align-items: center; "><label title="Add to Comparison List"> Compare <input type="checkbox" class="compareCheck" id="cmp_66ac1c7f3ef83657573a66a3"></label></div><a class="assessLink" coord_id="66ac1c7f3ef83657573a66a3" href="/assess" target="_blank" title="Structure Assessment">Structure Assessment<i class="glyphicon glyphicon-new-window" style="font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a></div></td></tr><tr id="cid_66ab9bd93ef83657573069bf" ><td rowspan="2" class="displayStructureWrapper"><label title="Select to display 3D structure"><input type="radio" name="displayStructure"/></label></td><td class="pdbDesc">Crystal structure of the A variant of human alpha1-acid glycoprotein and amitriptyline complex</td><td><div class="dropdown pdblinks"><a class="dropdown-toggle" data-toggle="dropdown">3apv</a><ul class="dropdown-menu pull-right"><li title="Protein Databank in Europe"><a href="https://www.ebi.ac.uk/pdbe/entry/pdb/3apv" target="_blank">PDBe</a></li><li title="Protein Databank in Knowledge Base"><a href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/3apv" target="_blank">PDBe-KB</a></li><li title="Protein Databank in Japan"><a href="https://pdbj.org/mine/summary/3apv" target="_blank">PDBj</a></li><li title="Protein Databank Summary"><a href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=3apv" target="_blank">PDBsum</a></li><li title="Research Collaboratory for Structural Bioinformatics Protein Data Bank"><a href="https://www.rcsb.org/structure/3apv" target="_blank">RCSB</a></li><li title="SWISS-MODEL Template Library"><a href="/templates/3apv" target="_blank">SMTL</a></li></ul></div></td><td>monomer</td><td nowrap="nowrap"><span style="display:none">21-190</span><div id="range_66ab9bd93ef83657573069bf" seqLength="201" resFrom="21" resTo="190" title="Range: 21-190"></div></td><td>99.41</td><td>1×<span title="Amitriptyline">TP0;</span> 1×<span title="ACETIC ACID">ACY;</span></td></tr><tr id="cid_66ab9bd93ef83657573069bf" class="tablesorter-childRow" ><td colspan="7"><div class="smtools" ><a href="/repository/66ab9bd93ef83657573069bf.pdb" target="_blank" title="Download Coordinates PDB Format"> Download <i class="glyphicon glyphicon-download-alt"></i></a><div style="display:flex; align-items: center; "><label title="Add to Comparison List"> Compare <input type="checkbox" class="compareCheck" id="cmp_66ab9bd93ef83657573069bf"></label></div><a class="assessLink" coord_id="66ab9bd93ef83657573069bf" href="/assess" target="_blank" title="Structure Assessment">Structure Assessment<i class="glyphicon glyphicon-new-window" style="font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a></div></td></tr></tbody></table><h4>1 SWISS-MODEL model</h4><table style="margin:0px" class="table noborder tablesorter allStructuresList" ><thead><tr><th></th><th>Template</th><th>Oligo-state</th><th>QMEAN<wbr>DisCo</th><th>Range</th><th>Ligands</th><th>Trg-Tpl Seq id (%)</th></tr></thead><tbody><tr id="cid_6739891eb77a869313393d1d" ><td rowspan="2" class="displayStructureWrapper"><label title="Select to display 3D structure"><input type="radio" name="displayStructure"/></label></td><td><a style="color:#333;margin-right:8px;" href="/templates/3apx.1" target="_blank">3apx.1.A</a></td><td>monomer</td><td>0.89</td><td nowrap="nowrap"><span style="display:none">19-196</span><div id="range_6739891eb77a869313393d1d" seqLength="201" resFrom="19" resTo="196" title="Range: 19-196"></div></td><td>1×<span title="3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine">Z80;</span></td><td>99.45</td></tr><tr id="cid_6739891eb77a869313393d1d" class="tablesorter-childRow" ><td colspan="7"><div class="smtools" ><div class="dropup pdblinks"><a class="dropup-toggle" data-toggle="dropup">Download <i class="glyphicon glyphicon-download-alt"></i></a><ul class="dropdown-menu" ><li><a href="/repository/6739891eb77a869313393d1f.cif" target="_blank" title="Download Coordinates ModelCIF format">ModelCIF format</a></li><li><a href="/repository/6739891eb77a869313393d1d.pdb" target="_blank" title="Download Coordinates PDB Format">PDB format</a></li></ul></div><a coord_id="6739891eb77a869313393d1d" class="report_link" target="_blank" title="View Model Report">Model report <i class="glyphicon glyphicon-file"></i></a><div style="display:flex; align-items: center; "><label title="Add to Comparison List"> Compare <input type="checkbox" class="compareCheck" id="cmp_6739891eb77a869313393d1d"></label></div><a class="assessLink" coord_id="6739891eb77a869313393d1d" href="/assess" target="_blank" title="Structure Assessment">Structure Assessment<i class="glyphicon glyphicon-new-window" style="font-size:.6em; vertical-align:text-top; margin-right:8px; margin-left:2px"></i></a></div></td></tr></tbody></table><h4 id="afTitle" style="display:none;"></h4><table id="afTable" style="margin:0px; display:none;" class="table noborder tablesorter allStructuresList"><thead><tr><th/><th>Model ID</th><th>Oligo-state</th><th>Avg pLDDT</th><th>Range</th><th>Trg-Mdl Seq Id (%)</th></tr></thead><tbody></tbody></table><h4 id="maTitle" style="display:none;"></h4><table id="maTable" style="margin:0px; display:none;" class="table noborder tablesorter allStructuresList"><thead><tr><th/><th>Model ID</th><th>Oligo-state</th><th>Avg Confidence</th><th>Range</th><th>Trg-Mdl Seq id (%)</th></tr></thead><tbody></tbody></table></div></div><!-- end of structure list panel --><div style='margin-bottom: 32px;' id="alContainer"><h4><a style="color:#333;" href="#" onclick="$('#alignment-panel').toggle();$(this).find('i').toggle();$('.alignTbl').alignment('resizeToParent');return false;">Alignments <small><i class="glyphicon glyphicon-chevron-down" style="display:none"></i><i class="glyphicon glyphicon-chevron-up"></i></small></a></h4><div id="alignment-panel"><div id="alignDivs"></div><div id="hiddenAlignments" style="display:none"></div><div id="blankAlignment" style="display:none;"><table cellpadding="0" cellspacing="0" class="alignTblContainer notranslate"><tr><td valign="top"><div class="hidden-print"><a id="options_TEMPLATE" class="poponthis glyphicon glyphicon-cog" style="color:#333;opacity:.7;margin-right:2px"></a></div></td><td valign="top"><table class="alignNameTbl" id="alignNameTblTEMPLATE" border="0" cellspacing="0" cellpadding="0"></table></td><td valign="top"><table class="alignTbl" id="alignTblTEMPLATE" cols_cookie="up3d_cols" border="0" cellspacing="0" cellpadding="0" ></table><div id="alignTblTEMPLATE_features" style="z-index:-1; position: absolute;"></div></td></tr></table><div id="offscreen_selection" style="position:absolute; top:-5000px; word-break: break-all;"></div></div></div></div></div><div id="right-panel"><div style="border: 1px solid #DDD; border-radius: 10px; padding:7px;"><div id="modelDetails" style="display:none;"><p><b>SWISS-MODEL </b> based on <a id="template" target="_blank"></a>, SMTL Version <span id="version"></span>; Trg-Tpl Seq Id <span id="seqid"></span>. <small><i><span id="description"></span></i></small></p> Average Model Confidence (QMEANDisCo): <span id="avgLocalQMEAN"></span><span id="avgLocalQMEANError"></span>; <span style="cursor:pointer" onclick="$('#qmeanCharts').toggle();updateQmeanCharts(true);$(this).find('i').toggle();resize();">Local Confidence <i class="glyphicon glyphicon-chevron-up" style="display:none;opacity: 0.8;"></i><i class="glyphicon glyphicon-chevron-down" style="opacity: 0.8;"></i></span></div><div id="3dbDetails" style="display: none;"><div id="3dbDescription"></div><div id="3dbConfSection"> Average Model Confidence (<span id="3dbLabel"></span>) : <span id="3dbConf">-</span>; <span style="cursor:pointer" onclick="$('#qmeanCharts').toggle();updateQmeanCharts(true);$(this).find('i').toggle();">Local Confidence <i class="glyphicon glyphicon-chevron-up" style="display:none;opacity: 0.8;"></i><i class="glyphicon glyphicon-chevron-down" style="opacity: 0.8;"></i></span></div></div><div id="strucDetails" style="display:none;"><span class="dropdown pdblinks"><a id="strucDropdown" class="dropdown-toggle" data-toggle="dropdown"></a><ul class="dropdown-menu"><li title="Protein Databank in Europe"><a basehref="https://www.ebi.ac.uk/pdbe/entry/pdb/" target="_blank">PDBe</a></li><li title="Protein Databank in Knowledge Base"><a basehref="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/" target="_blank">PDBe-KB</a></li><li title="Protein Databank in Japan"><a basehref="https://pdbj.org/mine/summary/" target="_blank">PDBj</a></li><li title="Protein Databank Summary"><a basehref="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=" target="_blank">PDBsum</a></li><li title="Research Collaboratory for Structural Bioinformatics Protein Data Bank"><a basehref="https://www.rcsb.org/structure/" target="_blank">RCSB</a></li><li title="SWISS-MODEL Template Library"><a basehref="/templates/" target="_blank">SMTL</a></li></ul></span>: <span id="strucMethod"></span>. <i>"<span id="strucDesc"></span>"</i>. Released <span id="strucVersion"></span>. <span id="strucLigands"></span></div><p id="memDetails" style="display:none"><span id="memDetailsLabel">We predict this structure to be a membrane protein.</span><a class="smng-help" style="margin-right:8px;" href="/docs/help#membrane"></a><label style="font-weight:normal;">Show / Hide <input type="checkbox" id="membraneCB_" checked="checked" onclick="showMembrane($(this).attr('id').substring(11), $(this).prop('checked'))"></label></p><button class="btn btn-xs btn-default poponthis" id="ligandBtn" style="display:none; margin:0px 0px 2px 8px;">Ligands</button><div id="qmeanCharts" style="display:none; padding:0px 12px 0px 12px"><a href="#lq-chart" rel="lq-" class="fancybox"><div id="lq-chart-thumb"></div></a><div id="lq-chart" style="display:none"></div></div><div style="display:none"><div id="ligandContainer" style="overflow:auto; max-height:500px"><div id="ligandContents"><div class="loader"></div></div></div></div><div id="viewerWrapper" style="position:relative"><div style="position: absolute; z-index:100; right: 10px; top: 10px;"><div id="pv_status"></div><div id="ngl_status"></div></div><div id="pv" style="display:none;width:100%;height:100%;position:relative;"></div><div id="ngl" style="display:none;width:100%;height:100%;position:relative;"></div><div id="viewerSettings" style="position:absolute; bottom:10px; right:10px; z-index: 10;"><div class="dropup pull-left"><a id="options_" class="poponthis btn btn-sm btn-default"><i class="glyphicon glyphicon-cog"></i></a><button class="btn btn-sm btn-default" data-toggle="dropdown"><span style="margin-right:4px" id="repBtnLbl">Cartoon</span><b class="caret"></b></button><ul role="menu" class="dropdown-menu" style="min-width:10px"><li><a href="#" onclick="changeRep('cartoon');return false;">Cartoon</a></li><li><a href="#" onclick="changeRep('tube');return false;">Tube</a></li><li><a href="#" onclick="changeRep('trace');return false;">Trace</a></li><li><a href="#" onclick="changeRep('lines');return false;">Lines</a></li><li class="notPV"><a href="#" onclick="changeRep('ballAndStick');return false;">Ball+Stick</a></li><li class="notPV"><a href="#" onclick="changeRep('licorice');return false;">Licorice</a></li><li class="notPV"><a href="#" onclick="changeRep('hyperball');return false;">Hyperball</a></li><li class="notPV"><a href="#" onclick="changeRep('rope');return false;">Rope</a></li><li class="notPV"><a href="#" onclick="changeRep('surface');return false;">Surface</a></li><li class="notPV"><a href="#" onclick="changeRep('spacefill');return false;">Spacefill</a></li><li role="separator" class="notNGL divider"></li><li class="notNGL"><a href="#" onclick="changeRep('outline');return false;">Outline</a></li><li class="notNGL"><a href="#" onclick="changeRep('fog');return false;">Fog</a></li></ul></div><div class="dropup pull-left notPV"><button class="btn btn-sm btn-default" title="Take Snapshot of 3D Molecule" data-toggle="dropdown"><span class="glyphicon glyphicon-camera" style="margin-right:4px"></span><b class="caret"></b></button><ul role="menu" class="dropdown-menu" style="min-width:10px"><h6 class="dropdown-header">Background</h6><li><label style="padding-left: 20px; padding-right: 20px; white-space: nowrap; font-weight: normal;" onclick="event.stopPropagation();" title="Export snapshot with a transparent background"><input type="checkbox" id="snapshot_bg_transparent_checkbox" checked="checked"> Transparent</label></li><h6 class="dropdown-header">Resolution</h6><li><a href="#" onclick="takeSnapshot('.png', 1);return false;">Low</a></li><li><a href="#" onclick="takeSnapshot('.png', 2);return false;">Medium</a></li><li><a href="#" onclick="takeSnapshot('.png', 4);return false;">High</a></li><li><a href="#" onclick="takeSnapshot('.png', 10);return false;">Extreme</a></li></ul></div><button class="btn btn-sm btn-default notNGL" title="Take Snapshot of 3D Molecule" onclick="takeSnapshot('.png');return false;"><i class="glyphicon glyphicon-camera"></i></button><button class="btn btn-sm btn-default spinButton" title="Start rotation" onclick="spin(true);$('.spinButton').toggle();"><i class="glyphicon glyphicon-play"></i></button><button class="btn btn-sm btn-default spinButton" style="display:none" title="Stop rotation" onclick="spin(false);$('.spinButton').toggle();"><i class="glyphicon glyphicon-pause"></i></button><button class="btn btn-sm btn-default" title="Detach" onclick="detach('/viewer/xx/');" ><i class="glyphicon glyphicon-eject"></i></button><button class="btn btn-sm btn-default" title="Reset" onclick="resetStructure();"><i class="glyphicon glyphicon-refresh"></i></button></div></div><!-- end viewerWrapper --></div></div></div><div style="display: none;"><div id="alignmentOptions" style="display:none;"><form class="alignmentOptions form form-inline" autocomplete="off"><div id="exportOptions" style="padding-bottom:8px"><b>Export Alignment</b><br><button type="button" class="btn btn-sm btn-default" onclick="$('#alignTbl'+$('#currentAlignmentIndex').val()).alignment('exportAlignment', {'format':'FASTA'});">FASTA format</button><button type="button" class="btn btn-sm btn-default" onclick="$('#alignTbl'+$('#currentAlignmentIndex').val()).alignment('exportAlignment', {'format':'ClustalW'});">Clustal Format</button><button type="button" class="btn btn-sm btn-default" onclick="$('.alTbl').first().alignment('html2image')">PNG Image</button></div><div><div id="colourOptions" style="padding-top:8px"><b>Colour Scheme </b><a class="smng-help" href="/docs/help#colour_schemes"></a><div id="fadeMismatches"><label class="inline checkbox" style="margin-right:12px;"><input type="checkbox" id="fadeMismatch_cb" onclick="$('.alignTbl').alignment('targetMismatch',{match:this.checked?'fade':null})" checked="checked" />Fade Mismatches</label><label class="inline checkbox"><input type="checkbox" id="enhanceMismatch_cb" onclick="$('.alignTbl').alignment('targetMismatch',{match:this.checked?'enhance':null})" />Enhance Mismatches</label></div><label class="confLabel"><input title="Per residue confidence colours" type="radio" name="csRadioGroup" id="qmean_localButton" value="qmean_local" checked="checked" />Confidence<sup>gradient</sup></label><label class="confLabel"><input title="Confidence classes" type="radio" name="csRadioGroup" id="confClassButton" value="confClass" checked="checked" />Confidence<sup>class</sup></label><label><input type="radio" name="csRadioGroup" id="indelsButton" value="indels" />Indels</label><label><input type="radio" name="csRadioGroup" id="chainButton" value="chain" >Chain</label><label><input type="radio" name="csRadioGroup" id="uniqueChainButton" value="uniqueChain" >Unique Chain</label><label><input type="radio" name="csRadioGroup" id="rainbowButton" value="rainbow" checked="checked">Rainbow</label><label><input type="radio" name="csRadioGroup" id="secstrucButton" value="secstruc" checked="checked">2° Structure</label><label><input type="radio" name="csRadioGroup" id="bfactorButton" value="bfactor" >Bfactor</label><label><input type="radio" name="csRadioGroup" id="bfactorRangeButton" value="bfactor_range" >Bfactor Range</label><label><input type="radio" name="csRadioGroup" id="clustalButton" value="clustal" />Clustal</label><label><input type="radio" name="csRadioGroup" id="hydrophobicButton" value="hydrophobic" />Hydrophobic</label><label><input type="radio" name="csRadioGroup" id="sizeButton" value="size" />Size</label><label><input type="radio" name="csRadioGroup" id="chargedButton" value="charged" />Charged</label><label><input type="radio" name="csRadioGroup" id="polarButton" value="polar" />Polar</label><label><input type="radio" name="csRadioGroup" id="prolineButton" value="proline" />Proline</label><label><input type="radio" name="csRadioGroup" id="serThrButton" value="serThr" />Ser/Thr</label><label><input type="radio" name="csRadioGroup" id="cysButton" value="cysteine" />Cysteine</label><label><input type="radio" name="csRadioGroup" id="aliphaticButton" value="aliphatic" />Aliphatic</label><label><input type="radio" name="csRadioGroup" id="aromaticButton" value="aromatic" />Aromatic</label><label><input type="radio" name="csRadioGroup" id="noColourButton" value="none" />No Colour</label></div><label class="checkbox" style="display: none" id="qmeanbraneLbl"><input type="checkbox" id="qmeanbraneCB" onclick="toggleQMEANBrane($(this).prop('checked'))">Use QMEANBrane values </label><table><tr><td><div style="margin-right:16px">Background</div></td><td><div style="height:16px; width:16px; border:1px solid #777;cursor:pointer;background-color:black" onclick="$('#bgColSlider').slider('value',0);"></div></td><td style="width:220px"><div id="bgColSlider" style="margin:8px"></div></td><td><div style="height:16px; width:16px; border:1px solid #777;cursor:pointer;background-color:white" onclick="$('#bgColSlider').slider('value',255);"></div></td></tr></table></div><div id="viewerSelect" style="padding-top:8px"><b>3D Viewer</b><br><label><input type="radio" name="3dRG" value="NGL" checked="checked" />NGL</label><label><input type="radio" name="3dRG" value="PV" />PV</label></div></form><div id="formattedAlignment" style="width:610px;height:470px;" class="fancy_box_swap"><label class="checkbox-inline" ><select style="height:28px;width:150px;" class="form-control" name="alignmentFormatSelect" id="alignmentFormatSelect" onchange="$('.alignTbl').first().alignment('changeExportFormat')"><option value="FASTA" selected="selected">FASTA</option><option value="Multi FASTA">Multi FASTA</option><option value="ClustalW">ClustalW</option></select></label><button type="button" class="btn btn-sm btn-default" onclick="$('.alignTbl').first().alignment('html2image')">PNG</button><div align="center"><textarea name="formattedAlignmentTextarea" id="formattedAlignmentTextarea" style="margin-top:8px;font-family:'Courier New', Courier, monospace; font-size:12px;width:100%;height:400px"></textarea></div></div></div><input type="hidden" id="currentAlignmentIndex" value=""></div></div><div id="loginForm" style="display:none;text-align:center;"></div><footer class="footer hidden-print"><div id="sib_footer"><ul class="list-inline" style="margin-bottom:0px; padding-bottom:4px;padding-top:4px;"><li><a href="https://www.sib.swiss"><span class="footerLg">Swiss Institute of Bioinformatics</span><span class="footerSm">SIB</span></a></li><li><a href="https://www.biozentrum.unibas.ch/research/researchgroups/overview/unit/schwede/">Schwede Group</a></li><li><a href="mailto:mouseover@for.address" class="swissmodelContactRef">Contact Us</a></li><li><a href="/docs/terms_of_use">Terms of use</a></li><li class="pull-right"><a id="sib_footer_gototop" onclick="window.scrollTo(0,0);"><i class="glyphicon glyphicon-arrow-up"></i><span class="footerLg"> Back to the 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$('.coverage').each(function() { let id = $(this).attr('id'); let coverage = { }[id.split('_')[1]]; let width=$('#'+id).innerWidth(), height=$('#'+id).innerHeight(); let scale = width / coverage['seqlength']; let html = ''; let provider = id.indexOf('modcov')==0?'modcov':'pdbcov'; let col = (provider=='modcov'?'rgba(30,90,255,.8)':'rgba(30,150,90,.8)'); let title = ''; let from=0; for(let i=0; i<coverage[provider].length; i++) { if(title.length>0) title+="; "; title += coverage[provider][i][0]+"-"+coverage[provider][i][1]; let w = scale*(coverage[provider][i][0]-from); if(coverage[provider][i][0]>1) { w = Math.floor(w); if(w>0) html += '<div style="float:left; padding:0; margin:0; float:left; background-color:#FFF;height:'+height+'px; width:'+w+'px;"></div>'; } w = scale*(coverage[provider][i][1]-coverage[provider][i][0]); w = Math.floor(w); html+='<div style="float:left; padding:0; margin:0; background-color:'+col+';height:'+height+'px; width:'+w+'px;"></div>'; from = coverage[provider][i][1] } $('#'+id) .append(html) .attr('title', title); }); </script><script src="/static/js/bio-pv.min.js?v=1699869780"></script><script src="/static/js/ngl.js?v=1733130706"></script><script src="/static/js/smng.min.js?v=1730370256"></script><script src="/static/js/smr.min.js?v=1730370256"></script><script src="/static/js/raphael-min.js"></script><script> // We need these before PLIP script gets loaded (if it even does) var plip_bonds = new PLIP.Bonds(); var plip_residues = new PLIP.Residues(); var all_ligands = new PLIP.Ligands(); var extra_residues_selection = extra_residues_selection || []; var extra_ranges_selection = extra_ranges_selection || []; var on_viewer_ready_function = function(strucId, comp) { // a function to execute after the structure is loaded. // see in structure.js for how it is called comp.autoView(1000); }; $.tablesorter.addParser({ id: 'range', is: function(s) { return false; }, format: function(s) { return s.split('-')[0]; }, type: 'numeric' }); $(".allStructuresList") .each(function() { let rangeColumn = 4; if($(this).attr('id')=='allIsoformsList') rangeColumn = 5; $(this) .tablesorter({ widgets: ['zebra'], zebra : ['even', 'odd'], headerTemplate : '{content} {icon}', headers:{ 0: {sorter:false}, rangeColumn: {sorter:"range"} } }); }); if(!$.cookie('colourScheme')) chainMapping.defaultColourScheme = 'qmean_local'; $(document).ready(function() { $('.stringLink') .popover( { html : true, animation: false, placement: 'auto bottom', content: function() { return `<img class="stringLinkImg" src='https://string-db.org/api/image/network?identifier=${$(this).attr('stringId')}'>`; }, container: 'body', trigger:'hover' }); $('a.report_link').bind('mouseover', function() { $(this).attr('href', "/repository/xxxxxxxxxxxxxxxxxxxxxxxx/report" .replace('xxxxxxxxxxxxxxxxxxxxxxxx', $(this).attr('coord_id'))); }); $('a.assessLink').bind('mouseover', function() { $(this).attr('href', [$(this).attr('coord_id'),'smr','assess',''] .reverse().join('/')); }); $('div[id^=range_]').each( function(i, ele) { drawRange(ele); }); document.body.addEventListener('change', function(e) { const target = e.target; if(target.type === 'radio' && target.name === 'displayStructure') { const row = target.closest('tr[id]'); if(row) switchModel(row.getAttribute('id').substring(4)); } }); $('#ligandBtn') .popover({ html : true, placement: 'bottom', content: $('#ligandContainer'), container: 'body', template: '<div class="container popover ligand-popover"><div class="arrow"></div><div class="popover-content"></div></div>' }); let viewer = $.cookie('defaultViewer'); if(viewer==null) viewer='NGL'; if(window.innerWidth>768 && window.innerWidth<992) $('#left-panel').width('350px'); // Select the default structure. Uses the model in variable selectedModel. if(selectedModel) { selectModel(selectedModel); scrollToModel(); } showViewer(viewer, null, checkQParams); draw(primaryMD5); for(let i=0; i<data.length; i++) { if(data[i].visible && data[i].coord_id!=selectedModel) showDetails(data[i].coord_id, null, true); } showDetails(selectedModel); resize(); check3DBeacons(); }); var pv_viewer = pv.Viewer(document.getElementById('pv'), { background: [1,1,1], width: 300, height: 300, antialias: true, quality: 'high', outline: true, fog: true }); const coordURL = "/repository/00.pdb"; const templateURL = "/templates/XXXX.0"; const upURL = "/repository/uniprot/XXXXXX"; const plipURL_js = "/repository/plip/XXXXXX.js"; let jqxhr_js = jqxhr_html = null; let selectedModel= "66ac13223ef836575739ad6f"; const primaryMD5 = "55949a5c7a109a30e366c0648063b5a0"; const primaryAccessionType = "uniprot_ac"; const primaryAccession = "P19652"; const data = [{ "mnFrom":19, "mxTo":196, "visible":true, "coord_id":"66ac13223ef836575739ad6f", "plip_id" :"66ac2de987c1d3ee0641732c", "stoichiometry":"monomer", "description":"Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex", "version":"2011-02-23", "provider":"PDB", "entity":[ { "entity_type":"PRO", "md5":"55949a5c7a109a30e366c0648063b5a0","model_chain":"A", "trg_seq":"QIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKTLMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLCIPRSDVMYTDWKKDKCEPLEKQHEKERKQ", "tpl_seq":"QIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKTLMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLRIPRSDVMYTDWKKDKCEPLEKQHEKERKQ", "pdb_res_num":[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179], "templates":[{"up_id":"P19652","qname":"3apx","resolution":2.200000047683716,"method":"X-RAY DIFFRACTION","description":"Alpha-1-acid glycoprotein 2","alignment":{"tpl_seq":"QIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKTLMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLRIPRSDVMYTDWKKDKCEPLEKQHEKERKQ","trg_seq":"QIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKTLMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLCIPRSDVMYTDWKKDKCEPLEKQHEKERKQ","PDBeResNum":[[2,179]]},"mdlFrom":19,"mdlTo":196,"tplFrom":2,"seqid":99.438}] }, { "entity_type":"NPE", "md5":"45ef78e21cbce45cceefa6929ff15709","model_chain":"_","occurrence":1,"hetid":"Z80","description":"3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine"}, { "entity_type":"NPE", "md5":"70f06ee9bc809e11134d9d1daa16f710","model_chain":"_","occurrence":1,"hetid":"ACY","description":"ACETIC ACID"} ] },]; const membraneData = {}; function showMdlMembrane(strucId, show) { if(membraneData[strucId]) { if(!show) showMembrane(strucId, false); else if(show && $('#membraneCB_'+strucId+':checked').length==1) showMembrane(strucId, true); } } const sequenceData = { "55949a5c7a109a30e366c0648063b5a0": { "sequence":"MALSWVLTVLSLLPLLEAQIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKTLMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLCIPRSDVMYTDWKKDKCEPLEKQHEKERKQEEGES", "ac":"P19652", "features":[{"type":"VARIANT","start":38,"end":38,"desc":"R -> Q (in dbSNP:rs147969317)","ftid":"014667","dbsnp":"rs147969317"},{"type":"VARIANT","start":99,"end":99,"desc":"V -> A (in dbSNP:rs2636889)","ftid":"050172","dbsnp":"rs2636889"},{"type":"VARIANT","start":141,"end":141,"desc":"G -> R (in dbSNP:rs12685968)","ftid":"050173","dbsnp":"rs12685968"},{"type":"VARIANT","start":167,"end":167,"desc":"C -> R (in dbSNP:rs1126777)","ftid":"050174","dbsnp":"rs1126777"},{"type":"VARIANT","start":174,"end":174,"desc":"M -> V (in dbSNP:rs2636890)","ftid":"050175","dbsnp":"rs2636890"},{"type":"DISULFID","start":23,"end":165},{"type":"DISULFID","start":90,"end":183},{"type":"INTERPRO","start":40,"end":179,"desc":"Lipocalin\/cytosolic fatty-acid binding domain","interpro":"IPR000566","pfam":"PF00061"}] } }; $(document).ready( function() { let checkThese = ''; let localData = localStorage.getItem('model'); if(localData) { let models = JSON.parse(localData); for(let i=0; i<models.length; i++) { checkThese+=(i==0?'':',')+'#cmp_'+models[i].model_id; addClink(models[i].model_id, models.length); } if(checkThese.length>0) $(checkThese) .prop('checked', 'checked') } $('.compareCheck').not(checkThese).prop('checked',''); }); function addClink(modelId, selectedCount) { $('#cmp_'+modelId) .parent() .after("<a id='clink_"+modelId+"' href='/comparison/' class='compareLink' target='_blank'>" +selectedCount+" selected <i class='glyphicon glyphicon-new-window'/></a>"); } function updateSelectionCount(selectedCount) { $('.compareLink') .html(selectedCount+" selected <i class='glyphicon glyphicon-new-window'/>"); } async function toggleCompareItem(evt) { let model_id = evt.target.id.substring(4); if(!evt.target.checked) { $('#clink_'+model_id).remove(); let locStore = localStorage.getItem('model'); if(!locStore) return; locData = JSON.parse(locStore); for(let i=0; i<locData.length; i++) if(locData[i].model_id===model_id) { locData.splice(i,1); break; } updateSelectionCount(locData.length); localStorage.setItem('model', JSON.stringify(locData)); } else { let source = model_id.split('_')[0]; let isoform = evt.target.hasAttribute('isoform')?'-'+evt.target.getAttribute('isoform'):''; let postData = { model_id: model_id, source: source, csrfmiddlewaretoken: '00yIsbgEeEWwbZLuPu1GLT0v8o4VeYHM0hZkHyAVNoEMV5uaC2WHUAtwIQJJSzma' }; // this is smr if(evt.target.hasAttribute('provider')) postData.source = evt.target.getAttribute('provider'); else postData.source = 'smr' postData.uniprot_ac = 'P19652'+isoform; $.ajax({ type: 'POST', url:"/comparison/add/", data: postData, success: function(data) { let locStore = localStorage.getItem('model'); if(locStore==null) locData = []; else { locData = JSON.parse(locStore); for(let i=0; i<locData.length; i++) if(locData[i].model_id===model_id) return; } locData.push(data) localStorage.setItem('model', JSON.stringify(locData)); addClink(model_id, locData.length); updateSelectionCount(locData.length); }, error: function(response) { $(evt.target) .prop({checked: false, disabled: true}) .after('Could not add this model!'); } }); } } $(window).on('storage', comparison_updated); function comparison_updated(ev) { if (ev.originalEvent.key!='model') return; let checkThese = ''; let selectionCount = 0; if(ev.originalEvent.newValue) { checkThese = JSON.parse(ev.originalEvent.newValue) .map((m)=>'#cmp_'+m.model_id); selectionCount = checkThese.length; checkThese = checkThese.join(','); if(selectionCount) $(checkThese).prop('checked','checked'); } $('.compareCheck').not(checkThese).prop('checked',''); $('.compareLink').not(checkThese.replace(/#cmp/g,'#clink')).remove(); updateSelectionCount(selectionCount); } $(document).on('change', 'input.compareCheck', (e) => toggleCompareItem(e) ); </script><script> $('a.smng-help').append('<icon class="glyphicon glyphicon-question-sign"></i>'); $(document).on('click','a.smng-help',function() { window.open($(this).attr('href'), 'Help', 'width=920,height=600,left=20,top=100,directories=no,menubar=yes,toolbar=yes,' +'status=no,scrollbars=yes,resizable=no'); return false; }); $('a.swissmodelContactRef') .on('mouseover',function() { $(this).attr('href',["ch", ".", "nibas", "l@u", "mode", "-swiss", ":help", "to", "ail", "m"].reverse().join('')); $(this).off('mouseover'); }); function showLogin() { $('#loginForm') .load('/login', { 'csrfmiddlewaretoken':'00yIsbgEeEWwbZLuPu1GLT0v8o4VeYHM0hZkHyAVNoEMV5uaC2WHUAtwIQJJSzma' }, function() { $("<a href='#loginForm'/>'").fancybox().trigger('click'); $('#id_username').focus(); }); } function createAccount() { $('#loginForm') .load('/create_account', function() { $("<a href='#loginForm'/>'").fancybox().trigger('click'); $('#id_username').focus(); }); } </script></body></html>