What is SBIR/STTR?

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If you have questions or need additional information, we invite you to contact NCI's LiveHelp instant messaging service at https://livehelp.cancer.gov, or call the NCI's Contact Center 1-800-4-CANCER (1-800-422-6237) (toll-free from the United States)."> <svg xmlns="http://www.w3.org/2000/svg" height="24" viewBox="0 0 24 24" width="24" class="usa-icon" role="img" aria-hidden="true" focusable="false"> <path d="M0 0h24v24H0z" fill="none"/> <path d="M20 4H4c-1.1 0-1.99.9-1.99 2L2 18c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V6c0-1.1-.9-2-2-2zm0 14H4V8l8 5 8-5v10zm-8-7L4 6h16l-8 5z"/> </svg> <span class="usa-sr-only"> Email </span> </a> </section> </div> </div> <div id="page" class="grid-container"> <div class="grid-row grid-gap">  <div class="desktop:grid-col-3 nci-no-print"> <nav aria-label="Secondary navigation"> <ul class="usa-sidenav"> <li class="usa-sidenav__item"> <a href="/about" data-menu-id="26" class="usa-current usa-current--nci-ancestor">About</a> <ul class="usa-sidenav__sublist"> <li class="usa-sidenav__item"> <a href="/about/what-is-sbir-sttr" data-menu-id="41" class="usa-current" aria-current="page">What is SBIR/STTR?</a> </li> <li class="usa-sidenav__item"> <a href="/about/underrepresented-small-business" data-menu-id="56">Underrepresented Small Business </a> </li> <li class="usa-sidenav__item"> <a href="/about/innovation-lab-podcast" data-menu-id="331">Innovation Lab Podcast</a> </li> <li class="usa-sidenav__item"> <a href="/about/contact-staff" data-menu-id="31">Contact & Staff</a> </li> </ul> </li> </ul> </nav> </div> <div class="cgdpl desktop:grid-col-9"> <div id="content" class=""> <main class="contentzone has-section-nav" id="main-content"> <div data-drupal-messages-fallback class="hidden"></div>  <article> <div class="resize-content"> <h1> What is SBIR/STTR? </h1> <div id="cgvBody"> <p>NCI’s Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs support small businesses across the United States to develop innovative cancer technologies with strong potential to help people live longer, healthier lives.</p> <h2>Goals</h2> <p>The SBIR and STTR programs seek to:</p> <ul> <li>Stimulate technological innovation.</li> <li>Increase private-sector commercialization of federal research and development (R&D).</li> <li>Increase small business participation in federally funded research and development.</li> <li>Foster participation by minority and disadvantaged companies in technological innovation.</li> </ul> <h2>Program Differences</h2> <p>The SBIR and STTR programs offer different types of support and funding for small businesses. In both programs, the award is always made to the small business concern (i.e., not to the research institution).</p> <table class="table-default"> <thead> <tr> <th scope="col">SBIR</th> <th scope="col">STTR</th> </tr> </thead> <tbody> <tr> <td>Program for small business concerns to engage in federal R&D with the potential for commercialization<br> <em>Federal agencies with an extramural R&D budget >$100M</em></td> <td>Program to facilitate cooperative R&D between small business concerns and U.S. research institutions with the potential for commercialization<br> <i>Federal agencies with an extramural R&D budget >$1B</i></td> </tr> <tr> <td>$159M set aside for FY 2022</td> <td>$22M set aside for FY 2022</td> </tr> <tr> <td><b>Permits</b> research institution partners<br> (e.g., universities)</td> <td><b>Requires</b> research institution partners<br> (e.g., universities)</td> </tr> <tr> <td>The small business may outsource ~33% of Phase I activities and 50% of Phase II activities.</td> <td>The small business (for profit) should conduct a minimum of 40% of the work, and a U.S. research institution (non-profit) should conduct a minimum of 30%.</td> </tr> <tr> <td>The Program Director/Principal Investigator <b>must</b> be primarily employed (i.e., >50%) with the small business concern for the duration of the project period.</td> <td>There is no stipulation regarding primary employment by the Program Director/Principal Investigator (min. 10% effort to project).</td> </tr> </tbody> </table> <h2>Why seek SBIR/STTR funding?</h2> <div class="four-columns"> <div class="column1"> <div style="width: 60px;"><img alt="#" src="/sites/g/files/xnrzdm261/files/cgov_image/media_image/2022-06/30427_NCI_SBIR_Website_icons_v01-01.png"></div> <hr> <h5>Provides seed funding for innovative technology development<strong> </strong><b><span style="color:#ff5f00;">//</span></b></h5> <p>No repayment is required. It doesn’t impact stock or shares in any way (i.e., non-dilutive).</p> </div> <div class="column2"> <div style="width: 60px;"><img alt="#" src="/sites/g/files/xnrzdm261/files/cgov_image/media_image/2022-06/30427_NCI_SBIR_Website_Content_Revision_About_Icons_v01-05.png"></div> <hr> <h5>Allows small businesses to retain intellectual property rights<b> <span style="color:#ff5f00;">//</span></b></h5> <p>NIH does not request intellectual property rights for the SBIR- or STTR-funded technologies.</p> </div> <div class="column3"> <div style="width: 60px;"><img alt="#" src="/sites/g/files/xnrzdm261/files/cgov_image/media_image/2022-06/30427_NCI_SBIR_Website_icons_v01-10.png"></div> <hr> <h5>Provides recognition, verification, and visibility <b><span style="color:#ff5f00;">//</span></b></h5> <p>The NIH peer review system rigorously assesses every application.</p> </div> <div class="column4 end"> <div style="width: 60px;"><img alt="#" src="/sites/g/files/xnrzdm261/files/cgov_image/media_image/2022-06/30427_NCI_SBIR_Website_icons_v01-04.png"></div> <hr> <h5>Helps secure additional funding or support<b> <span style="color:#ff5f00;">//</span></b></h5> <p>NIH provides commercialization resources to help advance your project.</p> </div> </div> </div> </div> <footer class="article-footer"> <div class="document-dates horizontal"> <ul class="clearfix"> <li> <strong>Updated:</strong> <time datetime="2022-08-29T12:00:00Z">August 29, 2022</time> </li> </ul> </div> <div id="nvcgSlPublicUse"> <div class="slot-item only-SI"> <div class="public-use"> <div id="block-ncids-trans-public-use"> <p><em>If you would like to reproduce some or all of this content, see <a href="https://www.cancer.gov/policies/copyright-reuse">Reuse of NCI Information</a> for guidance about copyright and permissions. In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “What is SBIR/STTR? was originally published by the National Cancer Institute.”</em></p> </div> </div> </div> </div> </footer> </article> </main> </div> </div> <div class="desktop:grid-col-9 desktop:grid-offset-3"> <section class="cgdp-page-options cgdp-page-options--bottom" aria-label="Page options bottom"> <button class="usa-button usa-button--unstyled" onclick="window.print()"> <svg xmlns="http://www.w3.org/2000/svg" height="24" viewBox="0 0 24 24" width="24" class="usa-icon" role="img" aria-hidden="true" focusable="false"> <path d="M0 0h24v24H0z" fill="none"/> <path d="M19 8H5c-1.66 0-3 1.34-3 3v6h4v4h12v-4h4v-6c0-1.66-1.34-3-3-3zm-3 11H8v-5h8v5zm3-7c-.55 0-1-.45-1-1s.45-1 1-1 1 .45 1 1-.45 1-1 1zm-1-9H6v4h12V3z"/> </svg> <span class="usa-sr-only"> Print </span> </button> <a class="usa-button usa-button--unstyled" href="mailto:?subject=Information from the National Cancer Institute Web Site &body=I found this information on www.cancer.gov and I'd like to share it with you: https://sbir.cancer.gov/about/what-is-sbir-sttr %0D%0A%0D%0A NCI's Web site, www.cancer.gov, provides accurate, up-to-date, comprehensive cancer information from the U.S. government's principal agency for cancer research. 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