QBI | READY Center Announcement

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The center merges innovative academic research with industrial-scale genome engineering, including CRISPR gene-editing technology, to yield an intricate map of the interface between human proteins and disease mechanisms in infectious disease, cancer, and neuropathologies. The center will be led by Dr. Lee Spraggon and QBI’s Director Dr. Nevan Krogan.</p><p>With support from the UCSF Department of Psychiatry, the READY Center is contributing to a project funded by the California Institute for Regenerative Medicine (CIRM) to accelerate the discovery of mechanisms underlying psychiatric neurodevelopmental disorders (NPD). Led by QBI Investigator Dr. Tomasz Nowakowski, the project was awarded $13.7 million to advance research into the molecular and neurodevelopmental basis of schizophrenia, building on prior work in Autism commenced by the QBI Psychiatric Cell Map Initiative (PCMI). </p><p>This multidisciplinary scientific collaboration and the application of the READY center’s high-throughput cellular engineering approaches will allow for the development of the first-of-its-kind comprehensive molecular and proteomic landscape of schizophrenia. Using its advanced cell engineering platform, scientists at the READY Center will genetically edit human induced pluripotent stem cells (iPSCs) for the study of 32 high-risk schizophrenia genes and clinical variants and support ongoing CIRM-funded efforts to develop powerful genomic tools for future disease therapeutics.<br></p><p><b><u>About QBI: </u></b>The Quantitative Biosciences Institute (QBI) is an organized research unit reporting through the UCSF School of Pharmacy. QBI fosters collaborations across the biomedical and the physical sciences, seeking quantitative methods to address pressing problems in biology and biomedicine. Motivated by problems of human disease, QBI is committed to investigating fundamental biological mechanisms, because ultimately solutions to many diseases have been revealed by unexpected discoveries in the basic sciences. Learn more at qbi.ucsf.edu.<br></p><p><b><u>About UCSF:</u> </b>The University of California, San Francisco (UCSF) is exclusively focused on the health sciences and is dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. UCSF Health, which serves as UCSF’s primary academic medical center, includes top-ranked specialty hospitals and other clinical programs and has affiliations throughout the Bay Area. Learn more at ucsf.edu or see our Fact Sheet.</p><p><b><u>Media Contact:</u> </b>Gina Nguyen (ginat.nguyen@ucsf.edu)</p><p><br></p><p><br></p><p><br></p><p><br></p> </div> </div> </div> </div> </div>  </div> </section> <footer> <div class="container"> <div class="row footer-logo"> <ul><li><a href="" target="_blank"><img src="" alt="" class="img-responsive"></a></li></ul> </div> <div class="row foooter-address-bar"> <div class="col-xs-12 col-sm-12 col-md-4 col-lg-5"> <i class="fa fa-map-marker footer-map-icon" aria-hidden="true"></i> <p> <a href="http://www.google.com/maps/place/QB3/@37.7671424,-122.3962505,15.61z/data=!4m5!3m4!1s0x808f7fcf444d105f:0x87a610f66290621b!8m2!3d37.7673012!4d-122.3915362" target="_blank"> University of California, <br>1700 4th Street, <br>San Francisco, CA, 94158 </a> </p> </div> <div class="col-xs-12 col-sm-12 col-md-3 col-lg-2 padding-right"> <p> <i class="fa fa-envelope footer-envelope-icon" aria-hidden="true"></i> <a href="mailto:admin-qbi@ucsf.edu"> admin-qbi@ucsf.edu </a> </p> </div> <div class="col-xs-12 col-sm-12 col-md-3 col-lg-2 col-lg-offset-1"> <p> <i class="fa fa-phone footer-tel-icon" aria-hidden="true"></i> 415-476-6109 </p> </div> <div class="col-xs-12 col-sm-12 col-md-2 col-lg-2 footer-social-icon"> <ul> <ul> <li><a target="_blank" href="http://twitter.com/QBI_UCSF"><i class="fa fa-twitter twitter" aria-hidden="true"></i></a></li> <li><a target="_blank" href="http://www.facebook.com/qbiucsf/"><i class="fa fa-facebook facebook" aria-hidden="true"></i></a></li> <li class="last"><a target="_blank" href="http://www.instagram.com/qbi_ucsf"><i class="fa fa-instagram insta" aria-hidden="true"></i></a></li> </ul> </ul> </div> </div> <div class="row footer-links" id="footer-toggle" style="display: none;"> <div class="col-md-12"> <h2>RESOURCES </h2> </div> <div class="col-xs-12 col-md-12"> <ul id="main-navbar"><li><a href="https://qbi.ucsf.edu">Home Page</a></li><li><a href="https://qbi.ucsf.edu/aboutus">About Us</a></li><li><a href="https://qbi.ucsf.edu/investigators">Investigators</a></li><li><a href="https://qbi.ucsf.edu/research">Research</a></li><li><a href="https://qbi.ucsf.edu/technology">Technology</a></li><li><a href="https://qbi.ucsf.edu/grants">Grants</a></li><li><a href="https://qbi.ucsf.edu/mapping">Cell Mapping</a></li><li><a href="https://qbi.ucsf.edu/contact">Contact</a></li></ul> </div> </div> </div> </footer> <div class="footer-close-panel" id="footer-close-panel"> <div class="container"> <div class="row"> <div class="col-xs-12 col-sm-5 col-md-4 padding-right copyright-txt"> <p>©2019 The Regents of the University of California</p> </div> <div class="col-xs-12 col-sm-2 col-sm-offset-1 col-md-1 col-md-offset-2 more-button no-padding"> <div class="mobile-more-btn"> <p> <a id="menu-open-close"><span id="spantext">More</span> <img src="images/scroll-down.png" class="img-responsive footer-more"></a> </p> </div> </div> <div class="col-xs-12 col-sm-3 col-md-3 col-md-offset-2 text-right pull-right"> <p>Site design by <span><a href="http://www.goodvsevil.co" target="_blank">Good vs Evil</a></span></p> </div> </div> </div> </div>        -->         <script> // $(document).ready(function(){ // let remodalEl = $(".support-covid.remodal"); // /*let showedPopup = localStorage && localStorage.getItem('alreadyShowedStory');*/ // let showedPopup = true; // if(!showedPopup && remodalEl.length && $.remodal && Array.isArray($.remodal.lookup)){ // let inst = $.remodal.lookup[remodalEl.data("remodal")]; // setTimeout(function(){ // inst.open(); // if(localStorage){ // localStorage.setItem("alreadyShowedStory", true); // } // }, 1000); // } // }); </script> <script type='text/javascript' src='scripts/footer.js'></script> <script> $(document).ready(function() { $('.nav-tabs li').on('click',function () { element=$(this).find('a'); setTimeout(function () { background = element.css('background-color'); $('.nav-tabs').css('border-bottom',"2px solid " + background); },100) }) }); </script> </body> </html>

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QBI | READY Center Announcement