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class="firstHeading mw-first-heading"><span class="mw-page-title-main">Monica Justice</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. 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searchaux" style="display:none">American–Canadian developmental geneticist</div> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox biography vcard"><tbody><tr><th colspan="2" class="infobox-above" style="font-size:125%;"><div class="fn">Monica Justice</div></th></tr><tr><th scope="row" class="infobox-label">Born</th><td class="infobox-data"><div style="display:inline" class="birthplace">Kansas</div></td></tr><tr><th scope="row" class="infobox-label">Spouse</th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1151524712">.mw-parser-output .marriage-line-margin2px{line-height:0;margin-bottom:-2px}.mw-parser-output .marriage-line-margin3px{line-height:0;margin-bottom:-3px}.mw-parser-output .marriage-display-ws{display:inline;white-space:nowrap}</style> <div class="marriage-display-ws"><div style="display:inline-block;line-height:normal;">Robert A. Justice</div> <div style="display:inline-block;"></div>(<abbr title="married">m.</abbr> 1978)<wbr /></div></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></td></tr><tr><th colspan="2" class="infobox-header">Academic background</th></tr><tr><th scope="row" class="infobox-label">Education</th><td class="infobox-data">BSc, <a href="/wiki/Fort_Hays_State_University" title="Fort Hays State University">Fort Hays State University</a> <br /> PhD, 1987, <a href="/wiki/Kansas_State_University" title="Kansas State University">Kansas State University</a></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Thesis" title="Thesis">Thesis</a></th><td class="infobox-data"><i>Specific locus applications of ethylnitrosourea mutagenesis in the mouse: genetic dissection of the t-region of mouse chromosome 17 and characterization of the enu-induced quaking and brachyury alleles</i> (1987)</td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></tr><tr><th colspan="2" class="infobox-header">Academic work</th></tr><tr><th scope="row" class="infobox-label">Institutions</th><td class="infobox-data"><a href="/wiki/University_of_Toronto" title="University of Toronto">University of Toronto</a> <br /> <a href="/wiki/Baylor_College_of_Medicine" title="Baylor College of Medicine">Baylor College of Medicine</a></td></tr><tr style="display:none"><td colspan="2"> </td></tr></tbody></table> <p><b>Monica J. Justice</b> (<i>nee</i> Maxwell) is an American–Canadian developmental geneticist. She is the <a href="/wiki/Canada_Research_Chair" title="Canada Research Chair">Canada Research Chair</a> in Mammalian Molecular Genetics at the <a href="/wiki/University_of_Toronto" title="University of Toronto">University of Toronto</a> and Program Head of Genetics and Genome Biology at <a href="/wiki/Hospital_for_Sick_Children_(Toronto)" title="Hospital for Sick Children (Toronto)">SickKids Hospital</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Early_life_and_education">Early life and education</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Monica_Justice&action=edit&section=1" title="Edit section: Early life and education"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Justice was born in western <a href="/wiki/Kansas" title="Kansas">Kansas</a> and was raised on the family farm.<sup id="cite_ref-Senior_1-0" class="reference"><a href="#cite_note-Senior-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Growing up, she attended Quinter High School where she was inducted into the Quinter chapter of the <a href="/wiki/National_Honor_Society" title="National Honor Society">National Honor Society</a> as a junior.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Following high school, Justice enrolled a <a href="/wiki/Fort_Hays_State_University" title="Fort Hays State University">Fort Hays State University</a> and began working as a medical technologist at St. Francis Hospital.<sup id="cite_ref-wedding_3-0" class="reference"><a href="#cite_note-wedding-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> She worked as a technologist for six year before returning to school for her PhD in developmental genetics. During her doctoral studies, she helped to pioneer chemical mutagenesis approaches in mice.<sup id="cite_ref-Senior_1-1" class="reference"><a href="#cite_note-Senior-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Upon completing her PhD, Justice began a postdoctoral fellowship in the Mammalian Genetics Laboratory at the <a href="/wiki/National_Cancer_Institute" title="National Cancer Institute">National Cancer Institute</a>.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Career">Career</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Monica_Justice&action=edit&section=2" title="Edit section: Career"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Upon completing her fellowship, Justice was recruited by Allan Bradley to join the faculty at <a href="/wiki/Baylor_College_of_Medicine" title="Baylor College of Medicine">Baylor College of Medicine</a> (BCM) to continue her research in developing high-throughput methods for assigning functions to mammalian genes.<sup id="cite_ref-Senior_1-2" class="reference"><a href="#cite_note-Senior-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> As a professor of molecular and human genetics at BCM, she became a co-<a href="/wiki/Principal_investigator" title="Principal investigator">principal investigator</a> on a project to develop mouse models which would enable scientists to identify the function of protein-coding genes in the mammalian genome.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> Through a grant, Justice co-identified a mutation in a gene involved in the synthesis of cholesterol which led to the development of new treatments for <a href="/wiki/Rett_syndrome" title="Rett syndrome">Rett syndrome</a>.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p><p>Justice eventually left BCM to become a <a href="/wiki/Canada_Research_Chair" title="Canada Research Chair">Canada Research Chair</a> in Mammalian Molecular Genetics at the <a href="/wiki/University_of_Toronto" title="University of Toronto">University of Toronto</a> and <a href="/wiki/Canadian_Institutes_of_Health_Research" title="Canadian Institutes of Health Research">Canadian Institutes of Health Research</a>.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> In this role, she was elected a Fellow of the <a href="/wiki/American_Association_for_the_Advancement_of_Science" title="American Association for the Advancement of Science">American Association for the Advancement of Science</a>.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Personal_life">Personal life</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Monica_Justice&action=edit&section=3" title="Edit section: Personal life"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Justice married Robert A. Justice in 1978.<sup id="cite_ref-wedding_3-1" class="reference"><a href="#cite_note-wedding-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Monica_Justice&action=edit&section=4" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns 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.cs1-maint{color:#18911f}}</style><cite id="CITEREFSenior2013" class="citation journal cs1">Senior, Kathryn (July 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701205">"Of Mice and Men, and Medicine: an interview with Monica Justice"</a>. <i>Disease Models & Mechanisms</i>. <b>6</b> (4): 871–873. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1242%2Fdmm.011809">10.1242/dmm.011809</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701205">3701205</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23828642">23828642</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Disease+Models+%26+Mechanisms&rft.atitle=Of+Mice+and+Men%2C+and+Medicine%3A+an+interview+with+Monica+Justice&rft.volume=6&rft.issue=4&rft.pages=871-873&rft.date=2013-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3701205%23id-name%3DPMC&rft_id=info%3Apmid%2F23828642&rft_id=info%3Adoi%2F10.1242%2Fdmm.011809&rft.aulast=Senior&rft.aufirst=Kathryn&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3701205&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" 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Retrieved <span class="nowrap">February 11,</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Monica+Justice&rft.pub=Sick+Kids&rft_id=https%3A%2F%2Fwww.sickkids.ca%2Fen%2Fstaff%2Fj%2Fmonica-justice%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPicton2011" class="citation web cs1">Picton, Glenna (September 29, 2011). <a rel="nofollow" class="external text" href="https://www.bcm.edu/news/nih-34-million-for-knockout-mouse-project">"NIH awards $34 million to Baylor College of Medicine for Knockout Mouse Project"</a>. Baylor College of Medicine<span class="reference-accessdate">. Retrieved <span class="nowrap">February 12,</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=NIH+awards+%2434+million+to+Baylor+College+of+Medicine+for+Knockout+Mouse+Project&rft.pub=Baylor+College+of+Medicine&rft.date=2011-09-29&rft.aulast=Picton&rft.aufirst=Glenna&rft_id=https%3A%2F%2Fwww.bcm.edu%2Fnews%2Fnih-34-million-for-knockout-mouse-project&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPicton2013" class="citation web cs1">Picton, Glenna (July 26, 2013). <a rel="nofollow" class="external text" href="https://www.bcm.edu/news/statins-improve-symptoms-rett-mouse-model">"Statins improve symptoms in Rett mouse model"</a>. Baylor College of Medicine<span class="reference-accessdate">. Retrieved <span class="nowrap">February 12,</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Statins+improve+symptoms+in+Rett+mouse+model&rft.pub=Baylor+College+of+Medicine&rft.date=2013-07-26&rft.aulast=Picton&rft.aufirst=Glenna&rft_id=https%3A%2F%2Fwww.bcm.edu%2Fnews%2Fstatins-improve-symptoms-rett-mouse-model&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.eurekalert.org/news-releases/903908">"Statins suppress rett syndrome symptoms in mice"</a>. Eurekalert. July 28, 2013<span class="reference-accessdate">. Retrieved <span class="nowrap">February 12,</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Statins+suppress+rett+syndrome+symptoms+in+mice&rft.pub=Eurekalert&rft.date=2013-07-28&rft_id=https%3A%2F%2Fwww.eurekalert.org%2Fnews-releases%2F903908&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.chairs-chaires.gc.ca/chairholders-titulaires/profile-eng.aspx?profileId=3342">"Monica Justice"</a>. Government of Canada. 29 November 2012<span class="reference-accessdate">. Retrieved <span class="nowrap">February 12,</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Monica+Justice&rft.pub=Government+of+Canada&rft.date=2012-11-29&rft_id=https%3A%2F%2Fwww.chairs-chaires.gc.ca%2Fchairholders-titulaires%2Fprofile-eng.aspx%3FprofileId%3D3342&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.sickkids.ca/en/news/archive/2017/congratulations-to-our-staff-on-their-recent-awards-and-accomplishments-/">"Congratulations to our staff on their recent awards and accomplishments"</a>. Sick Kids. March 22, 2017<span class="reference-accessdate">. Retrieved <span class="nowrap">February 12,</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Congratulations+to+our+staff+on+their+recent+awards+and+accomplishments&rft.pub=Sick+Kids&rft.date=2017-03-22&rft_id=https%3A%2F%2Fwww.sickkids.ca%2Fen%2Fnews%2Farchive%2F2017%2Fcongratulations-to-our-staff-on-their-recent-awards-and-accomplishments-%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMonica+Justice" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl 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