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id="cph1" class="container internal"> <div class="row"> <div class="row" data-sf-element="Row"> <div id="Contentplaceholder1_TABED6CC5010_Col00" class="sf_colsIn col-md-9" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div > <div class="sf-Long-text" ><div class="no-wrap"><img class="pad-right" src="/images/librariesprovider23/agenda/25/icon_ubq.png?sfvrsn=cb3ec729_1" alt="Degraders & Molecular Glues: Beyond Oncology Icon" /><div><h3>Cambridge Healthtech Institute’s Inaugural</h3><h1>Degraders & Molecular Glues: Beyond Oncology</h1><h2>Designing and Optimizing PROTACs and Glue Modalities for Diverse Therapeutic Indications</h2><h4>April 14, 2025</h4></div></div><p style="margin:0in;"> </p><p>Protein degraders and molecular glues are being developed to disrupt protein-protein interactions and to hijack the ubiquitin-proteasome, lysosome, and autophagy systems for targeted protein degradation. While most of the hetero-bifunctional degraders like proteolysis-targeting chimeras (PROTACs) and monovalent degraders like molecular glues are being used to target cancer, there are some headwinds driving non-oncology indications as well. This inaugural symposium that focuses on applications of Degraders & Molecular Glues: Beyond Oncology will be followed by a two-part conference on Degraders & Molecular Glues which emphasizes the growing use of targeted protein degradation and induced proximity as a new therapeutic approach.</p></div> </div> <div > <div class="sf-Long-text" ><p style="margin:0in;"> </p><p style="margin:0in;"><b>Coverage will likely include:</b></p><p style="margin:0in;"> </p><ul type="disc"><li>Emerging PROTACs, molecular glues, and new degrader modalities for non-oncology indications</li><li>Update on degraders in the clinic for inflammation, CNS, and more</li><li>Finding new ligases and mechanisms for targeted degradation in diverse therapeutic areas</li><li>Pursuing extracellular and hard-to-drug intracellular targets for degradation</li><li>Exploring degradation of RNA and lipids as drug targets for intervention</li></ul><p style="margin:0in;"> </p><p style="margin:0in;"><b>The deadline for submission is October 7</b><b>, 2024</b><b>.</b></p><p style="margin:0in;"> </p><p style="margin:0in;"><i>All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.</i></p><p style="margin:0in;"> </p><p style="margin:0in;"><b>Opportunities for Participation:</b></p><p style="margin:0in 0in 0in 0.5in;"> </p><ul><li>To submit a <b>podium presentation</b>, please <a href="/speaker-proposal" data-sf-ec-immutable="">click here</a>. <p style="margin:0in;"> </p></li><li>To become a <b>sponsor</b>, <a href="/sponsorship-opportunities" data-sf-ec-immutable="">click here</a>. <p style="margin:0in 0in 0in 0.5in;"> </p></li><li>To present a <b>poster</b>, <a href="/posters" data-sf-ec-immutable="">click here</a>. <p style="margin:0in 0in 0in 0.5in;"> </p></li> </ul></div> </div> <div > <div class="sf-Long-text" ><hr /><p style="margin:0in;"><b>Please click <a href="https://www.drugdiscoverychemistry.com/protein-degradation-molecular-glues">here</a> to continue to the agenda for Degraders & Molecular Glues – Part 1</b></p><br /><p style="margin:0in;"><b>For more details on the conference, please contact:</b></p><p style="margin:0in;">Tanuja Koppal, PhD<b></b></p><p style="margin:0in;">Senior Conference Director</p><p style="margin:0in;">Cambridge Healthtech Institute</p><p style="margin:0in;">Email: <a href="mailto:tkoppal@healthtech.com">tkoppal@healthtech.com</a></p><p style="margin:0in;"> </p><p style="margin:0in;"><b>For sponsorship information, please contact:</b></p><p style="margin:0in;">Kristin Skahan<b></b></p><p style="margin:0in;">Senior Business Development Manager</p><p style="margin:0in;">Cambridge Healthtech Institute</p><p style="margin:0in;">Phone: (+1) 781-972-5431</p><p style="margin:0in;">Email: <a href="mailto:kskahan@healthtech.com">kskahan@healthtech.com</a></p></div> </div> </div> <div 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