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Custom Degrader Services | Tocris Bioscience
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value="CF">Central African Republic</option><option value="TD">Chad</option><option value="CL">Chile</option><option value="CN">China</option><option value="CO">Colombia</option><option value="CR">Costa Rica</option><option value="HR">Croatia</option><option value="CY">Cyprus</option><option value="CZ">Czech Republic</option><option value="DK">Denmark</option><option value="DJ">Djibouti</option><option value="DM">Dominica</option><option value="DO">Dominican Republic</option><option value="EC">Ecuador</option><option value="EG">Egypt</option><option value="SV">El Salvador</option><option value="GQ">Equatorial Guinea</option><option value="ER">Eritrea</option><option value="EE">Estonia</option><option value="ET">Ethiopia</option><option value="FK">Falkland Islands</option><option value="FJ">Fiji</option><option value="FI">Finland</option><option value="FR">France</option><option value="PF">French Polynesia</option><option value="GA">Gabon</option><option value="GM">Gambia</option><option value="GE">Georgia</option><option value="DE">Germany</option><option value="GH">Ghana</option><option value="GI">Gibraltar</option><option value="GR">Greece</option><option value="GD">Grenada</option><option value="GP">Guadeloupe</option><option value="GU">Guam</option><option value="GT">Guatemala</option><option value="GN">Guinea</option><option value="GW">Guinea-Bissau</option><option value="GY">Guyana</option><option value="HT">Haiti</option><option value="HN">Honduras</option><option value="HK">Hong Kong S.A.R., China</option><option value="HU">Hungary</option><option value="IS">Iceland</option><option value="IN">India</option><option value="ID">Indonesia</option><option value="IQ">Iraq</option><option value="IE">Ireland</option><option value="IL">Israel</option><option value="IT">Italy</option><option value="CI">Ivory Coast</option><option value="JM">Jamaica</option><option value="JP">Japan</option><option value="JO">Jordan</option><option value="KZ">Kazakhstan</option><option value="KE">Kenya</option><option value="KW">Kuwait</option><option value="KG">Kyrgyzstan</option><option value="LV">Latvia</option><option value="LB">Lebanon</option><option value="LS">Lesotho</option><option value="LR">Liberia</option><option value="LI">Liechtenstein</option><option value="LT">Lithuania</option><option value="LU">Luxembourg</option><option value="MK">Macedonia</option><option value="MG">Madagascar</option><option value="MW">Malawi</option><option value="MY">Malaysia</option><option value="ML">Mali</option><option value="MT">Malta</option><option value="MH">Marshall Islands</option><option value="MR">Mauritania</option><option value="MX">Mexico</option><option value="MD">Moldova</option><option value="MC">Monaco</option><option value="MN">Mongolia</option><option value="ME">Montenegro</option><option value="MA">Morocco</option><option value="MZ">Mozambique</option><option value="MM">Myanmar</option><option value="NA">Namibia</option><option value="NP">Nepal</option><option value="NL">Netherlands</option><option value="AN">Netherlands Antilles</option><option value="NC">New Caledonia</option><option value="NZ">New Zealand</option><option value="NI">Nicaragua</option><option value="NE">Niger</option><option value="NG">Nigeria</option><option value="MP">Northern Mariana Islands</option><option value="NO">Norway</option><option value="OM">Oman</option><option value="PK">Pakistan</option><option value="PW">Palau</option><option value="PA">Panama</option><option value="PG">Papua New Guinea</option><option value="PY">Paraguay</option><option value="PE">Peru</option><option value="PH">Philippines</option><option value="PL">Poland</option><option value="PT">Portugal</option><option value="PR">Puerto Rico</option><option value="QA">Qatar</option><option value="RO">Romania</option><option value="RW">Rwanda</option><option value="KN">Saint Kitts and Nevis</option><option value="LC">Saint Lucia</option><option value="MF">Saint Martin (French part)</option><option value="WS">Samoa</option><option value="SA">Saudi Arabia</option><option value="SN">Senegal</option><option value="RS">Serbia</option><option value="SL">Sierra Leone</option><option value="SG">Singapore</option><option value="SK">Slovakia</option><option value="SI">Slovenia</option><option value="SB">Solomon Islands</option><option value="ZA">South Africa</option><option value="KR">South Korea</option><option value="ES">Spain</option><option value="LK">Sri Lanka</option><option value="SR">Suriname</option><option value="SZ">Swaziland</option><option value="SE">Sweden</option><option value="CH">Switzerland</option><option value="TW">Taiwan, China</option><option value="TZ">Tanzania</option><option value="TH">Thailand</option><option value="TG">Togo</option><option value="TT">Trinidad and Tobago</option><option value="TN">Tunisia</option><option value="TR">Turkey</option><option value="UG">Uganda</option><option value="UA">Ukraine</option><option value="AE">United Arab Emirates</option><option value="GB">United Kingdom</option><option value="US" selected="selected">United States</option><option value="UY">Uruguay</option><option value="UZ">Uzbekistan</option><option value="VA">Vatican</option><option value="VE">Venezuela</option><option value="VN">Vietnam</option><option value="YE">Yemen</option><option value="ZM">Zambia</option><option value="ZW">Zimbabwe</option></select></div></div><div class="form-item form-item-telephone form-type-textfield form-group"> <label class="control-label" for="edit-telephone">Telephone</label> <input class="form-control form-text" type="text" id="edit-telephone" name="telephone" value="" size="60" maxlength="255" /></div><div class="form-item form-item-email form-type-emailfield form-group"> <label class="control-label" for="edit-email">Email <span class="form-required" title="This field is required.">*</span></label> <input class="form-control form-text form-email required" type="email" id="edit-email" name="email" value="" size="60" maxlength="255" /></div><div class="form-item form-item-preferred-contact-method form-type-radios form-group"> <label class="control-label" for="edit-preferred-contact-method">Preferred Contact Method <span class="form-required" title="This field is required.">*</span></label> <div id="edit-preferred-contact-method" class="form-radios"><div class="form-item form-item-preferred-contact-method form-type-radio radio"> <label class="control-label" for="edit-preferred-contact-method-email"><input type="radio" id="edit-preferred-contact-method-email" name="preferred-contact-method" value="email" class="form-radio" />E-mail</label> </div><div class="form-item form-item-preferred-contact-method form-type-radio radio"> <label class="control-label" for="edit-preferred-contact-method-telephone"><input type="radio" id="edit-preferred-contact-method-telephone" name="preferred-contact-method" value="telephone" class="form-radio" />Telephone</label> </div></div></div><div id="edit-quick-links-txt" class="form-item form-type-item form-group"><p>Please complete the relevant sections of the forms below, for either <a href="#edit-building-blocks-header">Custom Degrader Building Block Quotes</a> or <a href="#edit-synthesis-project-header">Custom Degrader Synthesis Projects</a>.</p></div><div id="edit-contact-divider" class="form-item form-type-item form-group"><hr></div><div class="fullname-textfield"><div class="form-item form-item-fullname form-type-textfield form-group"> <label class="control-label" for="edit-fullname">Leave this field blank</label> <input autocomplete="off" class="form-control form-text" type="text" id="edit-fullname" name="fullname" value="" size="20" maxlength="128" /></div></div><div id="edit-building-blocks-header" class="form-item form-type-item form-group"><h3>Please Complete for Custom Degrader Building Block Quotes</h3></div><div id="edit-building-blocks-info" class="form-item form-type-item form-group"><p>We offer custom synthesis of E3 ligase ligand – linker panels to assist your degrader discovery project. If you already know the structures that you require, please enter the following information:</p></div><fieldset class="blkgrp panel panel-default form-wrapper" id="edit-bulk-group"> <div class="panel-body" id="edit-bulk-group-body"> <fieldset class="grp1 panel panel-default form-wrapper" id="edit-product-group1"> <div class="panel-body" id="edit-product-group1-body"> <div class="form-item form-item-compound-name1 form-type-textfield form-group"> <label class="control-label" for="edit-compound-name1">Compound Name</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-compound-name1" name="compound_name1" value="" size="60" maxlength="255" /></div><div class="form-item form-item-casno1 form-type-textfield form-group"> <label class="control-label" for="edit-casno1">CAS Number</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-casno1" name="casno1" value="" size="60" maxlength="255" /></div><div class="form-item form-item-smiles1 form-type-textfield form-group"> <label class="control-label" for="edit-smiles1">SMILES String</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-smiles1" name="smiles1" value="" size="60" maxlength="255" /></div><div class="form-item form-item-purity1 form-type-textfield form-group"> <label class="control-label" for="edit-purity1">Purity Required</label> <input placeholder="e.g. >98% (Optional)" class="form-control form-text" type="text" id="edit-purity1" name="purity1" value="" size="60" maxlength="255" /></div><div class="form-item form-item-quantity1 form-type-textfield form-group"> <label class="control-label" for="edit-quantity1">Quantity Required</label> <input placeholder="e.g. 1 x 5g or 10 x 50mg (Optional)" class="form-control form-text" type="text" id="edit-quantity1" name="quantity1" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline1 form-type-textfield form-group"> <label class="control-label" for="edit-deadline1">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline1" name="deadline1" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info1 form-type-textarea form-group"> <label class="control-label" for="edit-additional-info1">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info1" name="additional_info1" cols="60" rows="3"></textarea></div></div> </div> </fieldset> <fieldset class="grp1 grp_hidden panel panel-default form-wrapper" id="edit-product-group2"> <div class="panel-body" id="edit-product-group2-body"> <div class="form-item form-item-compound-name2 form-type-textfield form-group"> <label class="control-label" for="edit-compound-name2">Compound Name</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-compound-name2" name="compound_name2" value="" size="60" maxlength="255" /></div><div class="form-item form-item-casno2 form-type-textfield form-group"> <label class="control-label" for="edit-casno2">CAS Number</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-casno2" name="casno2" value="" size="60" maxlength="255" /></div><div class="form-item form-item-smiles2 form-type-textfield form-group"> <label class="control-label" for="edit-smiles2">SMILES String</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-smiles2" name="smiles2" value="" size="60" maxlength="255" /></div><div class="form-item form-item-purity2 form-type-textfield form-group"> <label class="control-label" for="edit-purity2">Purity Required</label> <input placeholder="e.g. >98% (Optional)" class="form-control form-text" type="text" id="edit-purity2" name="purity2" value="" size="60" maxlength="255" /></div><div class="form-item form-item-quantity2 form-type-textfield form-group"> <label class="control-label" for="edit-quantity2">Quantity Required</label> <input placeholder="e.g. 1 x 5g or 10 x 50mg (Optional)" class="form-control form-text" type="text" id="edit-quantity2" name="quantity2" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline2 form-type-textfield form-group"> <label class="control-label" for="edit-deadline2">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline2" name="deadline2" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info2 form-type-textarea form-group"> <label class="control-label" for="edit-additional-info2">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info2" name="additional_info2" cols="60" rows="3"></textarea></div></div> </div> </fieldset> <fieldset class="grp1 grp_hidden panel panel-default form-wrapper" id="edit-product-group3"> <div class="panel-body" id="edit-product-group3-body"> <div class="form-item form-item-compound-name3 form-type-textfield form-group"> <label class="control-label" for="edit-compound-name3">Compound Name</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-compound-name3" name="compound_name3" value="" size="60" maxlength="255" /></div><div class="form-item form-item-casno3 form-type-textfield form-group"> <label class="control-label" for="edit-casno3">CAS Number</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-casno3" name="casno3" value="" size="60" maxlength="255" /></div><div class="form-item form-item-smiles3 form-type-textfield form-group"> <label class="control-label" for="edit-smiles3">SMILES String</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-smiles3" name="smiles3" value="" size="60" maxlength="255" /></div><div class="form-item form-item-purity3 form-type-textfield form-group"> <label class="control-label" for="edit-purity3">Purity Required</label> <input placeholder="e.g. >98% (Optional)" class="form-control form-text" type="text" id="edit-purity3" name="purity3" value="" size="60" maxlength="255" /></div><div class="form-item form-item-quantity3 form-type-textfield form-group"> <label class="control-label" for="edit-quantity3">Quantity Required</label> <input placeholder="e.g. 1 x 5g or 10 x 50mg (Optional)" class="form-control form-text" type="text" id="edit-quantity3" name="quantity3" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline3 form-type-textfield form-group"> <label class="control-label" for="edit-deadline3">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline3" name="deadline3" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info3 form-type-textarea form-group"> <label class="control-label" for="edit-additional-info3">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info3" name="additional_info3" cols="60" rows="3"></textarea></div></div> </div> </fieldset> <fieldset class="grp1 grp_hidden panel panel-default form-wrapper" id="edit-product-group4"> <div class="panel-body" id="edit-product-group4-body"> <div class="form-item form-item-compound-name4 form-type-textfield form-group"> <label class="control-label" for="edit-compound-name4">Compound Name</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-compound-name4" name="compound_name4" value="" size="60" maxlength="255" /></div><div class="form-item form-item-casno4 form-type-textfield form-group"> <label class="control-label" for="edit-casno4">CAS Number</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-casno4" name="casno4" value="" size="60" maxlength="255" /></div><div class="form-item form-item-smiles4 form-type-textfield form-group"> <label class="control-label" for="edit-smiles4">SMILES String</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-smiles4" name="smiles4" value="" size="60" maxlength="255" /></div><div class="form-item form-item-purity4 form-type-textfield form-group"> <label class="control-label" for="edit-purity4">Purity Required</label> <input placeholder="e.g. >98% (Optional)" class="form-control form-text" type="text" id="edit-purity4" name="purity4" value="" size="60" maxlength="255" /></div><div class="form-item form-item-quantity4 form-type-textfield form-group"> <label class="control-label" for="edit-quantity4">Quantity Required</label> <input placeholder="e.g. 1 x 5g or 10 x 50mg (Optional)" class="form-control form-text" type="text" id="edit-quantity4" name="quantity4" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline4 form-type-textfield form-group"> <label class="control-label" for="edit-deadline4">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline4" name="deadline4" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info4 form-type-textarea form-group"> <label class="control-label" for="edit-additional-info4">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info4" name="additional_info4" cols="60" rows="3"></textarea></div></div> </div> </fieldset> <fieldset class="grp1 grp_hidden panel panel-default form-wrapper" id="edit-product-group5"> <div class="panel-body" id="edit-product-group5-body"> <div class="form-item form-item-compound-name5 form-type-textfield form-group"> <label class="control-label" for="edit-compound-name5">Compound Name</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-compound-name5" name="compound_name5" value="" size="60" maxlength="255" /></div><div class="form-item form-item-casno5 form-type-textfield form-group"> <label class="control-label" for="edit-casno5">CAS Number</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-casno5" name="casno5" value="" size="60" maxlength="255" /></div><div class="form-item form-item-smiles5 form-type-textfield form-group"> <label class="control-label" for="edit-smiles5">SMILES String</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-smiles5" name="smiles5" value="" size="60" maxlength="255" /></div><div class="form-item form-item-purity5 form-type-textfield form-group"> <label class="control-label" for="edit-purity5">Purity Required</label> <input placeholder="e.g. >98% (Optional)" class="form-control form-text" type="text" id="edit-purity5" name="purity5" value="" size="60" maxlength="255" /></div><div class="form-item form-item-quantity5 form-type-textfield form-group"> <label class="control-label" for="edit-quantity5">Quantity Required</label> <input placeholder="e.g. 1 x 5g or 10 x 50mg (Optional)" class="form-control form-text" type="text" id="edit-quantity5" name="quantity5" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline5 form-type-textfield form-group"> <label class="control-label" for="edit-deadline5">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline5" name="deadline5" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info5 form-type-textarea form-group"> <label class="control-label" for="edit-additional-info5">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info5" name="additional_info5" cols="60" rows="3"></textarea></div></div> </div> </fieldset> <fieldset class="grp1 grp_hidden panel panel-default form-wrapper" id="edit-product-group6"> <div class="panel-body" id="edit-product-group6-body"> <div class="form-item form-item-compound-name6 form-type-textfield form-group"> <label class="control-label" for="edit-compound-name6">Compound Name</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-compound-name6" name="compound_name6" value="" size="60" maxlength="255" /></div><div class="form-item form-item-casno6 form-type-textfield form-group"> <label class="control-label" for="edit-casno6">CAS Number</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-casno6" name="casno6" value="" size="60" maxlength="255" /></div><div class="form-item form-item-smiles6 form-type-textfield form-group"> <label class="control-label" for="edit-smiles6">SMILES String</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-smiles6" name="smiles6" value="" size="60" maxlength="255" /></div><div class="form-item form-item-purity6 form-type-textfield form-group"> <label class="control-label" for="edit-purity6">Purity Required</label> <input placeholder="e.g. >98% (Optional)" class="form-control form-text" type="text" id="edit-purity6" name="purity6" value="" size="60" maxlength="255" /></div><div class="form-item form-item-quantity6 form-type-textfield form-group"> <label class="control-label" for="edit-quantity6">Quantity Required</label> <input placeholder="e.g. 1 x 5g or 10 x 50mg (Optional)" class="form-control form-text" type="text" id="edit-quantity6" name="quantity6" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline6 form-type-textfield form-group"> <label class="control-label" for="edit-deadline6">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline6" name="deadline6" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info6 form-type-textarea form-group"> <label class="control-label" for="edit-additional-info6">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info6" name="additional_info6" cols="60" rows="3"></textarea></div></div> </div> </fieldset> </div> </fieldset> <p id="ps1" class="clearfix"><a class="addblk btn btn-tertiary pull-right">Add another compound</a><a class="remblk pull-right"></a></p><div id="edit-building-blocks-info2" class="form-item form-type-item form-group"><p>Alternatively, if you would like us to assist with the design of a panel of building blocks, please enter the following information and we will contact you to discuss your requirements:</p></div><div class="form-item form-item-e3-ligase-ligand form-type-textfield form-group"> <label class="control-label" for="edit-e3-ligase-ligand">E3 Ligase Ligand(s)</label> <input placeholder="Please list all that apply (Optional)" class="form-control form-text" type="text" id="edit-e3-ligase-ligand" name="e3_ligase_ligand" value="" size="60" maxlength="255" /></div><div class="form-item form-item-linker-types form-type-textfield form-group"> <label class="control-label" for="edit-linker-types">Linker Type(s)</label> <input placeholder="Please list all that apply (Optional)" class="form-control form-text" type="text" id="edit-linker-types" name="linker_types" value="" size="60" maxlength="255" /></div><div class="form-item form-item-linker-lengths form-type-textfield form-group"> <label class="control-label" for="edit-linker-lengths">Linker Length(s)</label> <input placeholder="Please list all that apply (Optional)" class="form-control form-text" type="text" id="edit-linker-lengths" name="linker_lengths" value="" size="60" maxlength="255" /></div><div class="form-item form-item-functionality form-type-textfield form-group"> <label class="control-label" for="edit-functionality">Functionality</label> <input placeholder="Functionality(s) Required for Target Ligand Conjugation (Optional)" class="form-control form-text" type="text" id="edit-functionality" name="functionality" value="" size="60" maxlength="255" /></div><div class="form-item form-item-panel-size form-type-textfield form-group"> <label class="control-label" for="edit-panel-size">Number of Compounds</label> <input placeholder="Approx. Number of Compounds/Size of Panel Required (Optional)" class="form-control form-text" type="text" id="edit-panel-size" name="panel_size" value="" size="60" maxlength="255" /></div><div class="form-item form-item-deadline form-type-textfield form-group"> <label class="control-label" for="edit-deadline">Deadline</label> <input placeholder="(Optional)" class="form-control form-text" type="text" id="edit-deadline" name="deadline" value="" size="60" maxlength="255" /></div><div class="form-item form-item-additional-info form-type-textarea form-group"> <label class="control-label" for="edit-additional-info">Additional Information</label> <div class="form-textarea-wrapper"><textarea placeholder="(Optional)" class="form-control form-textarea" id="edit-additional-info" name="additional_info" cols="60" rows="3"></textarea></div></div><div id="edit-contact-divider2" class="form-item form-type-item form-group"><hr></div><div id="edit-synthesis-project-header" class="form-item form-type-item form-group"><h3>Please complete for Custom Degrader Synthesis Projects</h3></div><div id="edit-synthesis-project-info" class="form-item form-type-item form-group"><p>To discuss a custom degrader discovery project with our team, please provide a brief description below and we will contact you to discuss your requirements:</p></div><div class="form-item form-item-feedback form-type-textarea form-group"><div class="form-textarea-wrapper"><textarea placeholder="Brief description of your requirements" class="form-control form-textarea" id="edit-feedback" name="feedback" cols="60" rows="5"></textarea></div></div><hr/><p>Stay up to date with the latest products and literature from Tocris Bioscience and Bio-Techne.</p><div class="form-item form-item-chkboxemail form-type-checkbox checkbox"> <label class="control-label" for="edit-chkboxemail"><input type="checkbox" id="edit-chkboxemail" name="chkBoxEmail" value="1" class="form-checkbox" />I would like to receive marketing communications</label> </div><div class="small opt-in-txt"><em>By checking this box, I agree to receive relevant marketing communications regarding products, industry news, literature, and events from Bio-Techne and its brands: Tocris Bioscience, R&D Systems, Novus Biologicals, ProteinSimple and Advanced Cell Diagnostics. 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