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lymphadenopathy</title> <meta name="description" content="Search results for: cervical lymphadenopathy"> <meta name="keywords" content="cervical lymphadenopathy"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="cervical lymphadenopathy"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 245</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: cervical lymphadenopathy</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">245</span> Predictive Value of Primary Tumor Depth for Cervical Lymphadenopathy in Squamous Cell Carcinoma of Buccal Mucosa</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zohra%20Salim">Zohra Salim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To access the relationship of primary tumor thickness with cervical lymphadenopathy in squamous cell carcinoma of buccal mucosa. Methodology: A cross-sectional observational study was carried out on 80 Patients with biopsy-proven oral squamous cell carcinoma of buccal mucosa at Dow University of Health Sciences. All the study participants were treated with wide local excision of the primary tumor with elective neck dissection. Patients with prior head and neck malignancy or those with prior radiotherapy or chemotherapy were excluded from the study. Data was entered and analyzed on SPSS 21. Chi-squared test with 95% C.I and 80% power of the test was used to evaluate the relationship of tumor depth with cervical lymph nodes. Results: 50 participants were male, and 30 patients were female. 30 patients were in the age range of 20-40 years, 36 patients in the range of 40-60 years, while 14 patients were beyond age 60 years. Tumor size ranged from 0.3cm to 5cm with a mean of 2.03cm. Tumor depth ranged from 0.2cm to 5cm. 20% of the participants reported with tumor depth greater than 2.5cm, while 80% of patients reported with tumor depth less than 2.5cm. Out of 80 patients, 27 reported with negative lymph nodes, while 53 patients reported with positive lymph nodes. Conclusion: Our study concludes that relationship exists between the depth of primary tumor and cervical lymphadenopathy in squamous cell carcinoma of buccal mucosa. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=squamous%20cell%20carcinoma" title="squamous cell carcinoma">squamous cell carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20depth" title=" tumor depth"> tumor depth</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20lymphadenopathy" title=" cervical lymphadenopathy"> cervical lymphadenopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=buccal%20mucosa" title=" buccal mucosa"> buccal mucosa</a> </p> <a href="https://publications.waset.org/abstracts/85223/predictive-value-of-primary-tumor-depth-for-cervical-lymphadenopathy-in-squamous-cell-carcinoma-of-buccal-mucosa" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85223.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">237</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">244</span> Rt-Pcr Negative COVID-19 Infection in a Bodybuilding Competitor Using Anabolic Steroids: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mariana%20Branco">Mariana Branco</a>, <a href="https://publications.waset.org/abstracts/search?q=Nahida%20Sobrino"> Nahida Sobrino</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristina%20Neves"> Cristina Neves</a>, <a href="https://publications.waset.org/abstracts/search?q=M%C3%A1rcia%20Santos"> Márcia Santos</a>, <a href="https://publications.waset.org/abstracts/search?q=Afonso%20Granja"> Afonso Granja</a>, <a href="https://publications.waset.org/abstracts/search?q=Jo%C3%A3o%20Rosa%20Oliveira"> João Rosa Oliveira</a>, <a href="https://publications.waset.org/abstracts/search?q=Joana%20Costa"> Joana Costa</a>, <a href="https://publications.waset.org/abstracts/search?q=Lu%C3%ADsa%20Castro%20Leite"> Luísa Castro Leite</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This case reports a COVID-19 infection in an unvaccinated adult man with no history of COVID-19 and no relevant clinical history besides anabolic steroid use, undergoing weaning with tamoxifen after a bodybuilding competition. The patient presented a 4cm cervical mass 3 weeks after COVID-19 infection in his cohabitants. He was otherwise asymptomatic and tested negative to multiple RT-PCR tests. Nevertheless, the IgG COVID-19 antibody was positive, suggesting the previous infection. This report raises a potential link between anabolic steroid use and atypical COVID-19 onset. Objectives: The goals of this paper are to raise a potential link between anabolic steroid use and atypical COVID-19 onset but also to report an uncommon case of COVID-19 infection with consecutive negative gold standard tests. Methodology: The authors used CARE guidelines for case report writing. Introduction: This case reports a COVID-19 infection case in an unvaccinated adult man, with multiple serial negative reverse transcription polymerase chain reaction (RT-PCR) test results, presenting with single cervical lymphadenopathy. Although the association between COVID-19 and lymphadenopathy is well established, there are no cases with this presentation, and consistently negative RT-PCR tests have been reported. Methodologies: The authors used CARE guidelines for case report writing. Case presentation: This case reports a 28-year-old Caucasian man with no previous history of COVID-19 infection or vaccination and no relevant clinical history besides anabolic steroid use undergoing weaning with tamoxifendue to participation in a bodybuilding competition. He visits his primary care physician because of a large (4 cm) cervical lump, present for 3 days prior to the consultation. There was a positive family history for COVID-19 infection 3 weeks prior to the visit, during which the patient cohabited with the infected family members. The patient never had any previous clinical manifestation of COVID-19 infection and, despite multiple consecutive RT-PCR testing, never tested positive. The patient was treated with an NSAID and a broad-spectrum antibiotic, with little to no effect. Imagiological testing was performed via a cervical ultrasound, followed by a needle biopsy for histologic analysis. Serologic testing for COVID-19 immunity was conducted, revealing a positive Anti-SARS-CoV-2 IgG (Spike S1) antibody, suggesting the previous infection, given the unvaccinated status of our patient Conclusion: In patients with a positive epidemiologic context and cervical lymphadenopathy, physicians should still consider COVID-19 infection as a differential diagnosis, despite negative PCR testing. This case also raises a potential link between anabolic steroid use and atypical COVID-19 onset, never before reported in scientific literature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=COVID-19" title="COVID-19">COVID-19</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20lymphadenopathy" title=" cervical lymphadenopathy"> cervical lymphadenopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=anabolic%20steroids" title=" anabolic steroids"> anabolic steroids</a>, <a href="https://publications.waset.org/abstracts/search?q=primary%20care" title=" primary care"> primary care</a> </p> <a href="https://publications.waset.org/abstracts/149610/rt-pcr-negative-covid-19-infection-in-a-bodybuilding-competitor-using-anabolic-steroids-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149610.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">116</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">243</span> Underdiagnosis of Supraclavicular Brachial Plexus Metastasis in the Shadow of Cervical Disc Herniation: Insights from a Lung Cancer Case Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eunhwa%20Jun">Eunhwa Jun</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This case report describes the misdiagnosis of a patient who presented with right arm pain as cervical disc herniation. The patient had several underlying conditions, including hypertension, diabetes mellitus, liver cirrhosis, a history of lung cancer with left lower lobe lobectomy, and adjuvant chemoradiotherapy. An external cervical spine MRI revealed central protruding discs at the C4-5-6-7 levels. Despite treatment with medication and epidural blocks, the patient's pain persisted. A C-RACZ procedure was planned, but the patient's pain had worsened before admission. Using ultrasound, a brachial plexus block was attempted, but the brachial plexus eluded clear visualization, hinting at underlying neurological complexities. Chest CT revealed a new, large soft tissue mass in the right supraclavicular region with adjacent right axillary lymphadenopathy, leading to the diagnosis of metastatic squamous cell carcinoma. Palliative radiation therapy and chemotherapy were initiated as part of the treatment plan, and the patient's pain score decreased to 3 out of 10 on the Numeric Rating Scale (NRS), revealing the pain was due to metastatic lung cancer. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=supraclavicula%20brachial%20plexus%20metastasis" title="supraclavicula brachial plexus metastasis">supraclavicula brachial plexus metastasis</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20disc%20herniation" title=" cervical disc herniation"> cervical disc herniation</a>, <a href="https://publications.waset.org/abstracts/search?q=brachial%20plexus%20block" title=" brachial plexus block"> brachial plexus block</a>, <a href="https://publications.waset.org/abstracts/search?q=metastatic%20lung%20cancer" title=" metastatic lung cancer"> metastatic lung cancer</a> </p> <a href="https://publications.waset.org/abstracts/185489/underdiagnosis-of-supraclavicular-brachial-plexus-metastasis-in-the-shadow-of-cervical-disc-herniation-insights-from-a-lung-cancer-case-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185489.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">44</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">242</span> Evaluation of P16, Human Papillomavirus Capsid Protein L1 and Ki67 in Cervical Intraepithelial Lesions: Potential Utility in Diagnosis and Prognosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hanan%20Alsaeid%20Alshenawy">Hanan Alsaeid Alshenawy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Cervical dysplasia, which is potentially precancerous, has increased in young women. Detection of cervical is important for reducing morbidity and mortality in cervical cancer. This study analyzes the immunohistochemical expression of p16, HPV L1 capsid protein and Ki67 in cervical intraepithelial lesions and correlates them with lesion grade to develop a set of markers for diagnosis and detect the prognosis of cervical cancer precursors. Methods: 75 specimens were analyzed including 15 cases CIN 1, 28 CIN 2, 20 CIN 3, and 12 cervical squamous carcinoma, besides 10 normal cervical tissues. They were stained for p16, HPV L1 and Ki-67. Sensitivity, specificity, predictive values and accuracy were evaluated for each marker. Results: p16 expression increased during the progression from CIN 1 to carcinoma. HPV L1 positivity was detected in CIN 2 and decreased gradually as the CIN grade increased but disappear in carcinoma. Strong Ki-67 expression was observed with high grades CIN and carcinoma. p16, HPV L1 and Ki67 were sensitive but with variable specificity in detecting CIN lesions. Conclusions: p16, HPV L1 and Ki67 are useful set of markers in establishing the risk of high-grade CIN. They complete each other to reach accurate diagnosis and prognosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=p16" title="p16">p16</a>, <a href="https://publications.waset.org/abstracts/search?q=HPV%20L1" title=" HPV L1"> HPV L1</a>, <a href="https://publications.waset.org/abstracts/search?q=Ki67" title=" Ki67"> Ki67</a>, <a href="https://publications.waset.org/abstracts/search?q=CIN" title=" CIN"> CIN</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20carcinoma" title=" cervical carcinoma"> cervical carcinoma</a> </p> <a href="https://publications.waset.org/abstracts/19766/evaluation-of-p16-human-papillomavirus-capsid-protein-l1-and-ki67-in-cervical-intraepithelial-lesions-potential-utility-in-diagnosis-and-prognosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19766.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">341</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">241</span> Knowledge of Pap Smear Test and Visual Inspection with Acetic Acid in Cervical Cancer Patients in Manado</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eric%20Ng">Eric Ng</a>, <a href="https://publications.waset.org/abstracts/search?q=Freddy%20W.%20Wagey"> Freddy W. Wagey</a>, <a href="https://publications.waset.org/abstracts/search?q=Frank%20M.%20M.%20Wagey"> Frank M. M. Wagey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Cervical cancer is the fourth most common cancer in women worldwide and the most common cancer in many low- and middle-income countries. The main causes are the lack of prevention programs and effective therapy, as well as the lack of knowledge about cervical cancer and awareness for early detection. The Pap smear test and visual inspection with acetic acid (VIA) allow the cervical lesion to be detected so that progression to cervical cancer can be avoided. Objective: The purpose of this study was to evaluate the knowledge of Pap smear test and VIA in cervical cancer patients. Methodology: A total of 67 cervical cancer patients in Manado who volunteered to participate in the research were identified as the sample. The data were collected during the month of November 2019-January 2020 with a questionnaire about the respondents' knowledge relating to Pap smear test and VIA. Questionnaire data were analysed using descriptive statistics. Results: Knowledge of pap smear among cervical cancer patients were good in 9 respondents (13.4%), moderate in 20 respondents (29.9%), and bad in 38 respondents (56.7%), whereas the knowledge of VIA was good in 13 respondents (19.4%), moderate in 15 respondents (22.4%), and bad in 39 respondents (58.2%). Conclusion: Majority of cervical cancer patients in Manado still had bad knowledge about Pap smear tests and VIA. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=knowledge" title=" knowledge"> knowledge</a>, <a href="https://publications.waset.org/abstracts/search?q=pap%20smear%20test" title=" pap smear test"> pap smear test</a>, <a href="https://publications.waset.org/abstracts/search?q=visual%20inspection%20with%20acetic%20acid" title=" visual inspection with acetic acid "> visual inspection with acetic acid </a> </p> <a href="https://publications.waset.org/abstracts/131564/knowledge-of-pap-smear-test-and-visual-inspection-with-acetic-acid-in-cervical-cancer-patients-in-manado" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/131564.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">171</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">240</span> Phylogenetic Study of L1 Protein Human Papillomavirus Type 16 From Cervical Cancer Patients in Bandung</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fitri%20Rahmi%20Fadhilah">Fitri Rahmi Fadhilah</a>, <a href="https://publications.waset.org/abstracts/search?q=Edhyana%20Sahiratmadja"> Edhyana Sahiratmadja</a>, <a href="https://publications.waset.org/abstracts/search?q=Ani%20Melani%20Maskoen"> Ani Melani Maskoen</a>, <a href="https://publications.waset.org/abstracts/search?q=Ratu%20Safitri"> Ratu Safitri</a>, <a href="https://publications.waset.org/abstracts/search?q=Supartini%20Syarif"> Supartini Syarif</a>, <a href="https://publications.waset.org/abstracts/search?q=Herman%20Susanto"> Herman Susanto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical cancer is the second most common cancer in women after breast cancer. In Indonesia, the incidence of cervical cancer cases is estimated at 25-40 per 100,000 women per year. Human papillomavirus (HPV) infection is a major cause of cervical cancer, and HPV-16 is the most common genotype that infects the cervical tissue. The major late protein L1 may be associated with infectivity and pathogenicity and its variation can be used to classify HPV isolates. The aim of this study was to determine the phylogenetic tree of HPV 16 L1 gene from cervical cancer patient isolates in Bandung. After confirming HPV-16 by Linear Array Genotyping Test, L1 gene was amplified using specific primers and subject for sequencing. Phylogenetic analysis revealed that HPV 16 from Bandung was in the subgroup of Asia and East Asia, showing the close host-agent relationship among the Asian type. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=L1%20HPV%2016" title="L1 HPV 16">L1 HPV 16</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title=" cervical cancer"> cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=bandung" title=" bandung"> bandung</a>, <a href="https://publications.waset.org/abstracts/search?q=phylogenetic" title=" phylogenetic"> phylogenetic</a> </p> <a href="https://publications.waset.org/abstracts/6541/phylogenetic-study-of-l1-protein-human-papillomavirus-type-16-from-cervical-cancer-patients-in-bandung" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6541.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">502</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">239</span> Levels of Anxiety during the 1st Stage of Labour, Respectively Cervical Effacement </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shpresa%20Agani">Shpresa Agani</a>, <a href="https://publications.waset.org/abstracts/search?q=Nysret%20%20Agani"> Nysret Agani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Studies have found that women, during the 1st stage of labour, respectively cervical effacement, experience anxiety. This study aims to measure the degree of anxiety during cervical effacement, using Hopkins Symptom Checklist-25 (HSCL-25) for measuring anxiety symptoms (HSCL-25). A randomized prospective study with 300 women during the 1st stage of labour was conducted where cervical effacement percentage in parallel with the symptoms of anxiety was examined. Anxiety degree levels were examined by HSCL-25. Results showed that 81% were primiparous, while 19% were multiparous. All participants experienced anxiety symptoms, and the degree of anxiety depended on the stage of the birth process. Groups-based modeling according to HSCL- 2 identified three distinct groups of anxiety symptoms: group 1 (low degree, 32 cases or 11%), group 2 (mild degree, 186 cases or 62%), and group 3 (high degree, 82 cases or 27%). Depending on the percentage of cervical effacement, the anxiety degree increased. In a cervical effacement of 0-60-%, 125 cases or 41.6% had symptoms of anxiety, while in a cervical effacement of 60-100%, 174 cases or 58.4% had symptoms of anxiety (Chi-Square X2 (4,N=300)=10.755, p=0.02). This study showed a correlation between cervical effacement and the degree of anxiety. Further, it was found that the majority of participants experienced symptoms of anxiety during the cervical effacement process. The degree of anxiety increased in direct proportion to the degree of the cervical effacement process. The higher the percentage of cervical effacement, the higher the degree of anxiety. A continuing assessment of the psychological well-being of women throughout the birth process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anxiety" title="anxiety">anxiety</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20effacement" title=" cervical effacement"> cervical effacement</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=HSCL-25" title=" HSCL-25"> HSCL-25</a> </p> <a href="https://publications.waset.org/abstracts/138189/levels-of-anxiety-during-the-1st-stage-of-labour-respectively-cervical-effacement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138189.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">204</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">238</span> Diagnostic Accuracy Of Core Biopsy In Patients Presenting With Axillary Lymphadenopathy And Suspected Non-Breast Malignancy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Monisha%20Edirisooriya">Monisha Edirisooriya</a>, <a href="https://publications.waset.org/abstracts/search?q=Wilma%20Jack"> Wilma Jack</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominique%20Twelves">Dominique Twelves</a>, <a href="https://publications.waset.org/abstracts/search?q=Jennifer%20Royds"> Jennifer Royds</a>, <a href="https://publications.waset.org/abstracts/search?q=Fiona%20Scott"> Fiona Scott</a>, <a href="https://publications.waset.org/abstracts/search?q=Nicola%20Mason"> Nicola Mason</a>, <a href="https://publications.waset.org/abstracts/search?q=Arran%20Turnbull"> Arran Turnbull</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Michael%20Dixon"> J. Michael Dixon</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Excision biopsy has been the investigation of choice for patients presenting with pathological axillary lymphadenopathy without a breast abnormality. Core biopsy of nodes can provide sufficient tissue for diagnosis and has advantages in terms of morbidity and speed of diagnosis. This study evaluates the diagnostic accuracy of core biopsy in patients presenting with axillary lymphadenopathy. Methods: Between 2009 and 2019, 165 patients referred to the Edinburgh Breast Unit had a total of 179 axillary lymph node core biopsies. Results: 152 (92%) of the 165 initial core biopsies were deemed to contain adequate nodal tissue. Core biopsy correctly established malignancy in 75 of the 78 patients with haematological malignancy (96%) and in all 28 patients with metastatic carcinoma (100%) and correctly diagnosed benign changes in 49 of 57 (86%) patients with benign conditions. There were no false positives and no false negatives. In 67 (85.9%) of the 78 patients with hematological malignancy, there was sufficient material in the first core biopsy to allow the pathologist to make an actionable diagnosis and not ask for more tissue sampling prior to treatment. There were no complications of core biopsy. On follow up, none of the patients with benign cores has been shown to have malignancy in the axilla and none with lymphoma had their initial disease incorrectly classified. Conclusions: This study shows that core biopsy is now the investigation of choice for patients presenting with axillary lymphadenopathy even in those suspected as having lymphoma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=core%20biopsy" title="core biopsy">core biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=excision%20biopsy" title=" excision biopsy"> excision biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=axillary%20lymphadenopathy" title=" axillary lymphadenopathy"> axillary lymphadenopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=non-breast%20malignancy" title=" non-breast malignancy"> non-breast malignancy</a> </p> <a href="https://publications.waset.org/abstracts/141187/diagnostic-accuracy-of-core-biopsy-in-patients-presenting-with-axillary-lymphadenopathy-and-suspected-non-breast-malignancy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141187.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">241</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">237</span> The Effect of Normal Cervical Sagittal Configuration in the Management of Cervicogenic Dizziness: A 1-Year Randomized Controlled Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Moustafa%20Ibrahim%20Moustafa">Moustafa Ibrahim Moustafa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this study was to determine the immediate and long term effects of a multimodal program, with the addition of cervical sagittal curve restoration and forward head correction, on severity of dizziness, disability, frequency of dizziness, and severity of cervical pain. 72 patients with cervicogenic dizziness, definite hypolordotic cervical spine, and forward head posture were randomized to experimental or a control group. Both groups received the multimodal program, additionally, the study group received the Denneroll cervical traction. All outcome measures were measured at three intervals. The general linear model indicated a significant group × time effects in favor of experimental group on measures of anterior head translation (F=329.4 P < .0005), cervical lordosis (F=293.7 P < .0005), severity of dizziness (F=262.1 P < .0005), disability (F=248.9 P < .0005), frequency of dizziness (F=53.9 P < .0005), and severity of cervical pain (F=350.1 P < .0005). The addition of Dennroll cervical traction to a multimodal program can positively affect dizziness management outcomes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=randomized%20controlled%20trial" title="randomized controlled trial">randomized controlled trial</a>, <a href="https://publications.waset.org/abstracts/search?q=traction" title=" traction"> traction</a>, <a href="https://publications.waset.org/abstracts/search?q=dizziness" title=" dizziness"> dizziness</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical" title=" cervical"> cervical</a> </p> <a href="https://publications.waset.org/abstracts/1499/the-effect-of-normal-cervical-sagittal-configuration-in-the-management-of-cervicogenic-dizziness-a-1-year-randomized-controlled-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1499.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">310</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">236</span> Pre-Processing of Ultrasonography Image Quality Improvement in Cases of Cervical Cancer Using Image Enhancement </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Retno%20Supriyanti">Retno Supriyanti</a>, <a href="https://publications.waset.org/abstracts/search?q=Teguh%20Budiono"> Teguh Budiono</a>, <a href="https://publications.waset.org/abstracts/search?q=Yogi%20Ramadhani"> Yogi Ramadhani</a>, <a href="https://publications.waset.org/abstracts/search?q=Haris%20B.%20Widodo"> Haris B. Widodo</a>, <a href="https://publications.waset.org/abstracts/search?q=Arwita%20Mulyawati"> Arwita Mulyawati</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical cancer is the leading cause of mortality in cancer-related diseases. In this diagnosis doctors usually perform several tests to determine the presence of cervical cancer in a patient. However, these checks require support equipment to get the results in more detail. One is by using ultrasonography. However, for the developing countries most of the existing ultrasonography has a low resolution. The goal of this research is to obtain abnormalities on low-resolution ultrasound images especially for cervical cancer case. In this paper, we emphasize our work to use Image Enhancement for pre-processing image quality improvement. The result shows that pre-processing stage is promising to support further analysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=mortality" title=" mortality"> mortality</a>, <a href="https://publications.waset.org/abstracts/search?q=low-resolution" title=" low-resolution"> low-resolution</a>, <a href="https://publications.waset.org/abstracts/search?q=image%20enhancement." title=" image enhancement. "> image enhancement. </a> </p> <a href="https://publications.waset.org/abstracts/26523/pre-processing-of-ultrasonography-image-quality-improvement-in-cases-of-cervical-cancer-using-image-enhancement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26523.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">636</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">235</span> Success Rate of Endotracheal Intubation Using Inline Stabilization with and without Cervical Hard Collar; A Comparative Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Welawat%20Tienpratarn">Welawat Tienpratarn</a>, <a href="https://publications.waset.org/abstracts/search?q=Chaiyaporn%20Yuksen"> Chaiyaporn Yuksen</a>, <a href="https://publications.waset.org/abstracts/search?q=Kasamon%20Aramvanitch"> Kasamon Aramvanitch</a>, <a href="https://publications.waset.org/abstracts/search?q=Karn%20Suttapanit"> Karn Suttapanit</a>, <a href="https://publications.waset.org/abstracts/search?q=Yahya%20Mankong"> Yahya Mankong</a>, <a href="https://publications.waset.org/abstracts/search?q=Nussareen%20Yaemluksanalert"> Nussareen Yaemluksanalert</a>, <a href="https://publications.waset.org/abstracts/search?q=Sansanee%20Meesawad"> Sansanee Meesawad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction : Application of a rigid cervical collar may interfere with the laryngeal view, and potentially lead to failed endotracheal intubation (ETI). This study aimed to compare intubation success rates while performing inline stabilization with and without cervical hard collar. Methods : This randomized prospective comparative study included paramedics working in the Department of Emergency Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand to compare the success rates of endotracheal intubation on manikin using inline stabilization with and without cervical hard collar. Results : 125 participants were evaluated; 63 in the rigid cervical collar and 62 in the non-cervical hard collar group. The rate of successful intubation was significantly higher using manual stabilization without cervical hard collar (61 (96.8%) vs. 55 (88.7%); p=0.048). The time required to successfully perform intubation was also shorter, with manual stabilization only (14.1 ±20.9 vs. 18.9±29.0; p = 0.081). Conclusion : It seems that, removal of the rigid cervical collar during ETI in patients with suspected traumatic spine injury could increase the intubation success rate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ntubation" title="ntubation">ntubation</a>, <a href="https://publications.waset.org/abstracts/search?q=Intratracheal" title="Intratracheal">Intratracheal</a>, <a href="https://publications.waset.org/abstracts/search?q=Spinal%20Injuries" title="Spinal Injuries">Spinal Injuries</a>, <a href="https://publications.waset.org/abstracts/search?q=Multiple%20trauma" title="Multiple trauma">Multiple trauma</a> </p> <a href="https://publications.waset.org/abstracts/142888/success-rate-of-endotracheal-intubation-using-inline-stabilization-with-and-without-cervical-hard-collar-a-comparative-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142888.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">126</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">234</span> In silico Analysis of Differentially Expressed Genes in High-Grade Squamous Intraepithelial Lesion and Squamous Cell Carcinomas Stages of Cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rahul%20Agarwal">Rahul Agarwal</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashutosh%20Singh"> Ashutosh Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical cancer is one of the women related cancers which starts from the pre-cancerous cells and a fraction of women with pre-cancers of the cervix will develop cervical cancer. Cervical pre-cancers if treated in pre-invasive stage can prevent almost all true cervical squamous cell carcinoma. The present study investigates the genes and pathways that are involved in the progression of cervical cancer and are responsible in transition from pre-invasive stage to other advanced invasive stages. The study used GDS3292 microarray data to identify the stage specific genes in cervical cancer and further to generate the network of the significant genes. The microarray data GDS3292 consists of the expression profiling of 10 normal cervices, 7 HSILs and 21 SCCs samples. The study identifies 70 upregulated and 37 downregulated genes in HSIL stage while 95 upregulated and 60 downregulated genes in SCC stages. Biological process including cell communication, signal transduction are highly enriched in both HSIL and SCC stages of cervical cancer. Further, the ppi interaction of genes involved in HSIL and SCC stages helps in identifying the interacting partners. This work may lead to the identification of potential diagnostic biomarker which can be utilized for early stage detection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=HSIL" title=" HSIL"> HSIL</a>, <a href="https://publications.waset.org/abstracts/search?q=microarray" title=" microarray"> microarray</a>, <a href="https://publications.waset.org/abstracts/search?q=SCC" title=" SCC"> SCC</a> </p> <a href="https://publications.waset.org/abstracts/72943/in-silico-analysis-of-differentially-expressed-genes-in-high-grade-squamous-intraepithelial-lesion-and-squamous-cell-carcinomas-stages-of-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/72943.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">233</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">233</span> Cervical Cell Classification Using Random Forests</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dalwinder%20Singh">Dalwinder Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Amandeep%20Verma"> Amandeep Verma</a>, <a href="https://publications.waset.org/abstracts/search?q=Manpreet%20Kaur"> Manpreet Kaur</a>, <a href="https://publications.waset.org/abstracts/search?q=Birmohan%20Singh"> Birmohan Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The detection of pre-cancerous changes using a Pap smear test of cervical cell is the important step for the early diagnosis of cervical cancer. The Pap smear test consists of a sample of human cells taken from the cervix which are analysed to detect cancerous and pre-cancerous stage of the given subject. The manual analysis of these cells is labor intensive and time consuming process which relies on expert cytotechnologist. In this paper, a computer assisted system for the automated analysis of the cervical cells has been proposed. We propose a morphology based approach to the nucleus detection and segmentation of the cytoplasmic region of the given single or multiple overlapped cell. Further, various texture and region based features are calculated from these cells to classify these into normal and abnormal cell. Experimental results on public available dataset show that our system has achieved satisfactory success rate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20tissue" title=" cervical tissue"> cervical tissue</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20morphology" title=" mathematical morphology"> mathematical morphology</a>, <a href="https://publications.waset.org/abstracts/search?q=texture%20features" title=" texture features"> texture features</a> </p> <a href="https://publications.waset.org/abstracts/29953/cervical-cell-classification-using-random-forests" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29953.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">526</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">232</span> Clinical Feature Analysis and Prediction on Recurrence in Cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ravinder%20Bahl">Ravinder Bahl</a>, <a href="https://publications.waset.org/abstracts/search?q=Jamini%20Sharma"> Jamini Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper demonstrates analysis of the cervical cancer based on a probabilistic model. It involves technique for classification and prediction by recognizing typical and diagnostically most important test features relating to cervical cancer. The main contributions of the research include predicting the probability of recurrences in no recurrence (first time detection) cases. The combination of the conventional statistical and machine learning tools is applied for the analysis. Experimental study with real data demonstrates the feasibility and potential of the proposed approach for the said cause. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=recurrence" title=" recurrence"> recurrence</a>, <a href="https://publications.waset.org/abstracts/search?q=no%20recurrence" title=" no recurrence"> no recurrence</a>, <a href="https://publications.waset.org/abstracts/search?q=probabilistic" title=" probabilistic"> probabilistic</a>, <a href="https://publications.waset.org/abstracts/search?q=classification" title=" classification"> classification</a>, <a href="https://publications.waset.org/abstracts/search?q=prediction" title=" prediction"> prediction</a>, <a href="https://publications.waset.org/abstracts/search?q=machine%20learning" title=" machine learning"> machine learning</a> </p> <a href="https://publications.waset.org/abstracts/11879/clinical-feature-analysis-and-prediction-on-recurrence-in-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11879.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">360</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">231</span> Uptake of Cervical Cancer Screening Services and Associated Factors at KISWA HCII, Kampala, Uganda</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mary%20Kiviiri%20Nakawuka">Mary Kiviiri Nakawuka</a>, <a href="https://publications.waset.org/abstracts/search?q=Mary%20Namugalu"> Mary Namugalu</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20Otiti"> Andrew Otiti</a> </p> <p class="card-text"><strong>Abstract:</strong></p> BACKGROUND Cervical cancer is the fourth most common cancer in women and seventh overall among all cancers worldwide. It accounts for about 7.5% of all female-cancer deaths with 85% occurring in low and middle-income countries and the first most common female cancer in women aged 15 to 44 years in Uganda with an annual number of new cases at 3,915 and 2,275 annual number of cervical cancer deaths in 2012 (ICO INFORMATION CENTRE ON HPV AND CANCER, 2017).Despite the available free cervical cancer screening services whose uptake has been documented to improve the chances of successful treatment of pre-cancers and cancers among women of reproductive age, there is a low uptake of these services thus we sought to examine the uptake of cervical cancer services and associated factors among women of reproductive age (25-49) attending the ART clinic of KISWA HCII in Kampala, Uganda METHODS The research was carried out in the ART clinic of KISWA HCII among 385 participants. An analytical, cross-sectional study with quantitative methods of data collection was used. The study adopted a non-probability convenience sampling method to select participants. Quantitative data was collected through structured questionnaires. RESULTS 72.2% of the participants were found to have been screened for cervical cancer. 36 % of the screened women had a positive HPV or VIA result ,59.2% of the screened women had a negative HPV or VIA result and 4.8% had an invalid HPV test result. Only 39.5% of the participants had adequate overall knowledge about cervical cancer, more than a third of the participants (50%) had moderate or low knowledge and minority of them (10.5%) had no knowledge. There was no significant association between the uptake of cervical cancer screening services among participants and their socio-demographic characteristics. CONCLUSIONS Although majority of the women surveyed had been screened for cervical cancer, a comparatively large number of participants had inadequate knowledge about cervical cancer and therefore there is still need to continue teaching about cervical cancer and this may include education campaigns, improvements to the accessibility and convenience of the screening services. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer%20%20uptake" title="cervical cancer uptake">cervical cancer uptake</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer%20screening" title=" cervical cancer screening"> cervical cancer screening</a>, <a href="https://publications.waset.org/abstracts/search?q=women%20of%20reproductive%20age." title=" women of reproductive age."> women of reproductive age.</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer%20knowledge" title=" cervical cancer knowledge"> cervical cancer knowledge</a> </p> <a href="https://publications.waset.org/abstracts/168731/uptake-of-cervical-cancer-screening-services-and-associated-factors-at-kiswa-hcii-kampala-uganda" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/168731.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">96</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">230</span> Clinical Outcomes and Surgical Complications in Patients with Cervical Disk Degeneration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mirzashahi%20Babak">Mirzashahi Babak</a>, <a href="https://publications.waset.org/abstracts/search?q=Mansouri%20Pejman"> Mansouri Pejman</a>, <a href="https://publications.waset.org/abstracts/search?q=Najafi%20Arvin"> Najafi Arvin</a>, <a href="https://publications.waset.org/abstracts/search?q=Farzan%20Mahmoud"> Farzan Mahmoud</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: There are several surgical treatment choices for cervical spondylotic myelopathy (CSM). The aim of this study is to evaluate clinical outcomes and surgical complications in patients with cervical disk degeneration (CDD) undergoing either anterior cervical discectomy with or without fusion or cervical laminectomy and fusion. Methods: This prospective case series study included 45 consecutive patients with cervical spondylotic myelopathy between January 2010 and November 2014. There were 28 males and 17 females, with a mean age of 47 (range 37-68) years. The mean clinical follow-up was 14 months (range 3-24 months). The Neck Disability Index (NDI), visual analog scale (VAS) neck and arm pain, Short Form-36 (SF-36) were used as the functional outcome measurements. All of the complications in our patients were recorded. Results: In our study group, 26 patients underwent only one or two level anterior cervical discectomy. Ten patients underwent anterior cervical discectomy and fusion (ACDF) and nine cases underwent posterior laminectomy and fusion. We have found a statistically significant improvement between mean preoperative (29, range 19-43) and postoperative (7, range 0-12) NDI scores following surgery (P < 0.05). Also, there was a statistically significant difference between pre and post-operative VAS and SF-36 score (p < 0.05). There was a 7% overall complication rate (n = 3). The only complication in our patients was surgical site cellulitis which has been managed with oral antibiotic therapy. Conclusion: Both anterior cervical discectomy with or without fusion or posterior laminectomy and fusion are safe and efficacious treatment options for the management of CSM. The clinical outcomes seem to be fairly reproducible. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical" title="cervical">cervical</a>, <a href="https://publications.waset.org/abstracts/search?q=myelopathy" title=" myelopathy"> myelopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=discectomy" title=" discectomy"> discectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=fusion" title=" fusion"> fusion</a>, <a href="https://publications.waset.org/abstracts/search?q=laminectomy" title=" laminectomy"> laminectomy</a> </p> <a href="https://publications.waset.org/abstracts/37427/clinical-outcomes-and-surgical-complications-in-patients-with-cervical-disk-degeneration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37427.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">350</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">229</span> Stories of Women With Cervical Cancer in Taiwan: A Narrative Analysis Research</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pei-Yu%20Lee">Pei-Yu Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study investigates the life experience and self-interpretation of female cervical cancer patients under Taiwanese cultural context. Through a Narrative Analysis Research approach, the study took six cervical cancer female patients with an average age of 58 years (ranging from 55-66 years) for an average of twice, 60 minutes each time, in-depth recorded interviews under their consent. After converting the interview recordings into transcripts, the study applied the Riessman approach to analyze the contents. The results revealed two major theme, including 1. The symbolic meaning of the cervix, and 2. Women's perseverance and compliance. Because of the illness metaphor of cervical cancer and the designation of women being family caregivers under the Chinese patriarchal culture, females with cervical cancer are not only patients but also responsible for being family and partner roles, in which contradictions of intimate relationships exist. Show the strength of perseverance and compliance in the course of life. On the other hand, they have to identify and recognize their roles in life and strive to determine the situation of coexisting with the disease to picture their life. The results showed that female cervical cancer patients not only need to combat the disease but also stand against the stigma and the traditional responsibility given to women. The researchers recommend that nurses should include cultural implications in their care of female cervical cancer patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=female" title="female">female</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title=" cervical cancer"> cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=narrative%20analysis%20research" title=" narrative analysis research"> narrative analysis research</a>, <a href="https://publications.waset.org/abstracts/search?q=taiwan" title=" taiwan"> taiwan</a> </p> <a href="https://publications.waset.org/abstracts/150548/stories-of-women-with-cervical-cancer-in-taiwan-a-narrative-analysis-research" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150548.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">98</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">228</span> Antioxidants: Some Medicinal Plants in Indian System of Medicine Work as Anti-cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kamini%20Kaushal">Kamini Kaushal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Medicinal plants of Ayurveda are effective in the treatment of cervical cancer. The aim of this paper is to assess anti cancerous activities of these medicinal plants against cancer. Most of the medicinal plants in Ayurveda are using to treat cervical cancer as name of disease as treatment of YONI VYAPADA. The selected plants has been studied scientifically in India and evidence based written since Vedic era. The compilation results showed potential anti cervical cancer activity of the tested plants. There plants are remaining under the dark due to lack of awareness, lack of popularity and barrier of language. Now this is the time to eye opener regarding the classical text and clinical evidences, so that we can give the hope to world's affected women from this disease. World is waiting for such type of remedy which is having zero side effects, low cost and effective. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti%20cancerous" title="anti cancerous">anti cancerous</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title=" cervical cancer"> cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=ayurveda" title=" ayurveda"> ayurveda</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=scientific%20study" title=" scientific study"> scientific study</a>, <a href="https://publications.waset.org/abstracts/search?q=classical%20text" title=" classical text"> classical text</a> </p> <a href="https://publications.waset.org/abstracts/36552/antioxidants-some-medicinal-plants-in-indian-system-of-medicine-work-as-anti-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/36552.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">431</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">227</span> Human Papillomavirus Type 16 E4 Gene Variation as Risk Factor for Cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yudi%20Zhao">Yudi Zhao</a>, <a href="https://publications.waset.org/abstracts/search?q=Ziyun%20Zhou"> Ziyun Zhou</a>, <a href="https://publications.waset.org/abstracts/search?q=Yueting%20Yao"> Yueting Yao</a>, <a href="https://publications.waset.org/abstracts/search?q=Shuying%20Dai"> Shuying Dai</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhiling%20Yan"> Zhiling Yan</a>, <a href="https://publications.waset.org/abstracts/search?q=Longyu%20Yang"> Longyu Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Chuanyin%20Li"> Chuanyin Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Li%20Shi"> Li Shi</a>, <a href="https://publications.waset.org/abstracts/search?q=Yufeng%20Yao"> Yufeng Yao</a> </p> <p class="card-text"><strong>Abstract:</strong></p> HPV16 E4 gene plays an important role in viral genome amplification and release. Therefore, a variation of the E4 gene nucleic acid sequence may affect the carcinogenicity of HPV16. In order to understand the relationship between the variation of HPV16 E4 gene and cervical cancer, this study was to amplify and sequence the DNA sequences of E4 genes in 118 HPV16-positive cervical cancer patients and 151 HPV16-positive asymptomatic individuals. After obtaining E4 gene sequences, the phylogenetic trees were constructed by the Neighbor-joining method for gene variation analysis. The results showed that: 1) The distribution of HPV16 variants between the case group and the control group differed greatly (P = 0.015)，and the Asian-American（AA）variant was likely to relate to the occurrence of cervical cancer. 2) DNA sequence analysis showed that there were significant differences in the distribution of 8 variants between the case group and the control group (P < 0.05). And 3) In European (EUR) variant, two variations, C3384T (L18L) and A3449G (P39P), were associated with the initiation and development of cervical cancer. The results suggested that the variation of HPV16 E4 gene may be a contributor affecting the occurrence as well as the development of cervical cancer, and different HPV16 variants may have different carcinogenic capability. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=HPV16" title=" HPV16"> HPV16</a>, <a href="https://publications.waset.org/abstracts/search?q=E4%20gene" title=" E4 gene"> E4 gene</a>, <a href="https://publications.waset.org/abstracts/search?q=variations" title=" variations"> variations</a> </p> <a href="https://publications.waset.org/abstracts/110019/human-papillomavirus-type-16-e4-gene-variation-as-risk-factor-for-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/110019.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">171</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">226</span> Morphometry of Cervical Spinal Cord in Rabbit Using Design-Based Stereology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hamed%20Chavoshi%20Pour">Hamed Chavoshi Pour</a>, <a href="https://publications.waset.org/abstracts/search?q=Javad%20Sadeghinejad"> Javad Sadeghinejad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The spinal cord is a long structure that starts at the end of the medulla oblongata and is located within the vertebral canal. Physiologically, the spinal cord connects the brain with the peripheral nervous system for sensory and motor activities. The cervical spinal cord is an area of particular interest in medicine and veterinary medicine due to the high prevalence of diseases in this region. This study describes the morphometric features of the cervical spinal cord in rabbits using design-unbiased stereology. The cervical spinal cords of five male rabbits were dissected, and slabs were taken according to systematic uniform random sampling. Each slab was embedded in paraffin and cut into a 6-µm thick section, and stained with cresyl violet 0.1% for stereological estimations. The total spinal cord volume, volume fraction of grey and white matter, and also dorsal and ventral horns were estimated using point counting and Cavalieri's estimator. The total cervical spinal cord volume was 0.98 ± 0.07 cm³. The relative volume of white matter and grey matter was 70.6 ± 1.7% and 29.31 ± 1.67%, respectively. The dorsal horn and ventral horn volume were 13.86 ± 1.36% and 14.9 ± 0.62% of the whole cervical spinal cord. This knowledge of rabbit spinal cord findings may serve as a foundation for a translational model in spinal cord experimental research and provide basic findings for the diagnosis and treatment of spinal cord disorders. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stereology" title="stereology">stereology</a>, <a href="https://publications.waset.org/abstracts/search?q=spinal%20cord" title=" spinal cord"> spinal cord</a>, <a href="https://publications.waset.org/abstracts/search?q=rabbit" title=" rabbit"> rabbit</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical" title=" cervical"> cervical</a> </p> <a href="https://publications.waset.org/abstracts/161334/morphometry-of-cervical-spinal-cord-in-rabbit-using-design-based-stereology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161334.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">76</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">225</span> Comparison of Cervical Length Using Transvaginal Ultrasonography and Bishop Score to Predict Succesful Induction</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lubena%20Achmad">Lubena Achmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Herman%20Kristanto"> Herman Kristanto</a>, <a href="https://publications.waset.org/abstracts/search?q=Julian%20Dewantiningrum"> Julian Dewantiningrum</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The Bishop score is a standard method used to predict the success of induction. This examination tends to be subjective with high inter and intraobserver variability, so it was presumed to have a low predictive value in terms of the outcome of labor induction. Cervical length measurement using transvaginal ultrasound is considered to be more objective to assess the cervical length. Meanwhile, this examination is not a complicated procedure and less invasive than vaginal touché. Objective: To compare transvaginal ultrasound and Bishop score in predicting successful induction. Methods: This study was a prospective cohort study. One hundred and twenty women with singleton pregnancies undergoing induction of labor at 37 – 42 weeks and met inclusion and exclusion criteria were enrolled in this study. Cervical assessment by both transvaginal ultrasound and Bishop score were conducted prior induction. The success of labor induction was defined as an ability to achieve active phase ≤ 12 hours after induction. To figure out the best cut-off point of cervical length and Bishop score, receiver operating characteristic (ROC) curves were plotted. Logistic regression analysis was used to determine which factors best-predicted induction success. Results: This study showed significant differences in terms of age, premature rupture of the membrane, the Bishop score, cervical length and funneling as significant predictors of successful induction. Using ROC curves found that the best cut-off point for prediction of successful induction was 25.45 mm for cervical length and 3 for Bishop score. Logistic regression was performed and showed only premature rupture of membranes and cervical length ≤ 25.45 that significantly predicted the success of labor induction. By excluding premature rupture of the membrane as the indication of induction, cervical length less than 25.3 mm was a better predictor of successful induction. Conclusion: Compared to Bishop score, cervical length using transvaginal ultrasound was a better predictor of successful induction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bishop%20Score" title="Bishop Score">Bishop Score</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20length" title=" cervical length"> cervical length</a>, <a href="https://publications.waset.org/abstracts/search?q=induction" title=" induction"> induction</a>, <a href="https://publications.waset.org/abstracts/search?q=successful%20induction" title=" successful induction"> successful induction</a>, <a href="https://publications.waset.org/abstracts/search?q=transvaginal%20sonography" title=" transvaginal sonography "> transvaginal sonography </a> </p> <a href="https://publications.waset.org/abstracts/65273/comparison-of-cervical-length-using-transvaginal-ultrasonography-and-bishop-score-to-predict-succesful-induction" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65273.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">325</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">224</span> Prevalence of High Risk Human Papillomavirus in Cervical Dysplasia and Cancer Samples from Twin Cities in Pakistan </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sana%20Gul">Sana Gul</a>, <a href="https://publications.waset.org/abstracts/search?q=Sheeba%20Murad"> Sheeba Murad</a>, <a href="https://publications.waset.org/abstracts/search?q=Aneela%20Javed"> Aneela Javed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Human Papilloma Virus (HPV) is small DNA virus mostly infecting mucosa and cutaneous keratinocytes. So far, more than 200 Human papillomaviruses are known. HPV have been divided into high- and low-risk on the basis of their oncogenic potential. High risk HPV is considered to be the main etiological cause for cervical cancer. Objective: Current study was designed to screen the local cervical cancer patients from the twin cities of Pakistan for the occurance of high risk HPV. Methodology: A total of 67 formalin fixed paraffin-embedded samples of cervical cancer biopsies were obtained from the government hospitals in Islamabad and Rawalpindi. Cervical cancer biopsies were examined for the presence of HPV DNA. Polymerase chain reaction (PCR) was used for the amplification of a region in the HPV-L1 gene for the general detection of the Papilloma virus and for the genotype specific detection of high risk HPV 16 and 18 using the GP5/GP6 primers and genotype specific primers respectively. Results: HPV DNA was detected in 59 out of 67 samples analyzed. 30 samples showed the presence of HPV16 while 22 samples were positive for HPV 18 . HPV subtype could not be determined in 7 samples. Conclusion: Our results show a strong association between HPV infection and cervical cancer among women in twin cities of Pakistan. One way to minimize the disease burden in relation to HPV infection in Pakistani population is the use of prophylactic vaccines and routine screening. An early diagnosis of HPV infection will allow better health management to reduce the risk of developing cervical cancer. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=Pakistan" title=" Pakistan"> Pakistan</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20papillomavirus" title=" human papillomavirus"> human papillomavirus</a>, <a href="https://publications.waset.org/abstracts/search?q=HPV%2016" title=" HPV 16"> HPV 16</a> </p> <a href="https://publications.waset.org/abstracts/43081/prevalence-of-high-risk-human-papillomavirus-in-cervical-dysplasia-and-cancer-samples-from-twin-cities-in-pakistan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43081.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">341</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">223</span> Study of Relation between P53 and Mir-146a Rs2910164 Polymorphism in Cervical Lesion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Rassi">Hossein Rassi</a>, <a href="https://publications.waset.org/abstracts/search?q=Marjan%20Moradi%20Fard"> Marjan Moradi Fard</a>, <a href="https://publications.waset.org/abstracts/search?q=Masoud%20Houshmand"> Masoud Houshmand </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Cervical cancer is multistep disease that is thought to result from an interaction between genetic background and environmental factors. Human papillomavirus (HPV) infection is the leading risk factor for cervical intraepithelial neoplasia(CIN)and cervical cancer. In other hand, some of p53 and miRNA polymorphism may plays an important role in carcinogenesis. This study attempts to clarify the relation of p53 genotypes and miR-146a rs2910164 polymorphism in cervical lesions. Method: Forty two archival samples with cervical lesion retired from Khatam hospital and 40 sample from healthy persons used as control group. A simple and rapid method was used to detect the simultaneous amplification of the HPV consensus L1 region and HPV-16,-18, -11, -31, 33 and -35 along with the b-globin gene as an internal control. We use Multiplex PCR for detection of P53 and miR-146a rs2910164 genotypes in our lab. Finally, data analysis was performed using the 7 version of the Epi Info(TM) 2012 software and test chi-square(x2) for trend. Results: Cervix lesions were collected from 42 patients with Squamous metaplasia, cervical intraepithelial neoplasia, and cervical carcinoma. Successful DNA extraction was assessed by PCR amplification of b-actin gene (99bp). According to the results, p53 GG genotype and miR-146a rs2910164 CC genotype was significantly associated with increased risk of cervical lesions in the study population. In this study, we detected 13 HPV 18 from 42 cervical cancer. Conclusion: The connection between several SNP polymorphism and human virus papilloma in rare researches were seen. The reason of these differences in researches' findings can result in different kinds of races and geographic situations and also differences in life grooves in every region. The present study provided preliminary evidence that a p53 GG genotype and miR-146a rs2910164 CC genotype may effect cervical cancer risk in the study population, interacting synergistically with HPV 18 genotype. Our results demonstrate that the testing of p53 codon 72 polymorphism genotypes and miR-146a rs2910164 polymorphism genotypes in combination with HPV18 can serve as major risk factors in the early identification of cervical cancers. Furthermore, the results indicate the possibility of primary prevention of cervical cancer by vaccination against HPV18 in Iran. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=p53" title=" p53"> p53</a>, <a href="https://publications.waset.org/abstracts/search?q=miR-146a" title=" miR-146a"> miR-146a</a>, <a href="https://publications.waset.org/abstracts/search?q=rs2910164" title=" rs2910164"> rs2910164</a>, <a href="https://publications.waset.org/abstracts/search?q=polymorphism" title=" polymorphism "> polymorphism </a> </p> <a href="https://publications.waset.org/abstracts/27788/study-of-relation-between-p53-and-mir-146a-rs2910164-polymorphism-in-cervical-lesion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27788.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">468</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">222</span> Investigation p53 and miR-146a rs2910164 Polymorphism in Cervical Lesion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Rassi">Hossein Rassi</a>, <a href="https://publications.waset.org/abstracts/search?q=Marjan%20Moradi%20fard"> Marjan Moradi fard</a>, <a href="https://publications.waset.org/abstracts/search?q=Masoud%20Houshmand"> Masoud Houshmand</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Cervical cancer is multistep disease that is thought to result from an interaction between genetic background and environmental factors. Human Papillomavirus (HPV) infection is the leading risk factor for Cervical Intraepithelial Neoplasia (CIN) and cervical cancer. In other hand, some of p53 and miRNA polymorphism may plays an important role in carcinogenesis. This study attempts to clarify the relation of p53 genotypes and miR-146a rs2910164 polymorphism in cervical lesions. Method: Forty two archival samples with cervical lesion retired from Khatam hospital and 40 sample from healthy persons used as control group. A simple and rapid method was used to detect the simultaneous amplification of the HPV consensus L1 region and HPV-16,-18, -11, -31, 33, and -35 along with the b-globin gene as an internal control. We use Multiplex PCR for detection of P53 and miR-146a rs2910164 genotypes in our lab. Finally, data analysis was performed using the 7 version of the Epi Info(TM) 2012 software and test chi-square(x2) for trend. Results: Cervix lesions were collected from 42 patients with Squamous metaplasia, cervical intraepithelial neoplasia, and cervical carcinoma. Successful DNA extraction was assessed by PCR amplification of b-actin gene (99 bp). According to the results, p53 GG genotype and miR-146a rs2910164 CC genotype was significantly associated with increased risk of cervical lesions in the study population. In this study, we detected 13 HPV 18 from 42 cervical cancer. Conclusion: The connection between several SNP polymorphism and human virus papilloma in rare researches were seen. The reason of these differences in researches' findings can result in different kinds of races and geographic situations and also differences in life grooves in every region. The present study provided preliminary evidence that a p53 GG genotype and miR-146a rs2910164 CC genotype may effect cervical cancer risk in the study population, interacting synergistically with HPV 18 genotype. Our results demonstrate that the testing of p53 codon 72 polymorphism genotypes and miR-146a rs2910164 polymorphism genotypes in combination with HPV18 can serve as major risk factors in the early identification of cervical cancers. Furthermore, the results indicate the possibility of primary prevention of cervical cancer by vaccination against HPV18 in Iran. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=miR-146a%20rs2910164%20polymorphism" title=" miR-146a rs2910164 polymorphism"> miR-146a rs2910164 polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=p53%20polymorphism" title=" p53 polymorphism"> p53 polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=intraepithelial" title=" intraepithelial"> intraepithelial</a>, <a href="https://publications.waset.org/abstracts/search?q=neoplasia" title=" neoplasia"> neoplasia</a>, <a href="https://publications.waset.org/abstracts/search?q=HPV" title=" HPV"> HPV</a> </p> <a href="https://publications.waset.org/abstracts/27789/investigation-p53-and-mir-146a-rs2910164-polymorphism-in-cervical-lesion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27789.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">398</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">221</span> Knowledge and Attitude of Final Year Undergraduate Nursing Students towards Prevention of Cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Afaf%20Abdallah">Afaf Abdallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Moawia%20Elsadig"> Moawia Elsadig </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Cervical cancer is the second most common women cancer among worldwide; representing 13% of female cancers. In Sudan, it ranks as the second most frequent cancer among women as other developing countries. Aim: Is to study awareness, attitude of nursing students towards cervical cancer prevention. The results: Most of the students were not aware of other screening methods than Pap smear test. However, half of the respondents showed positive attitudes towards HPV vaccination. More than two-thirds of respondents exhibited a positive attitude and were willing to undergo Pap smear in the future. Conclusion: The study shows that the majority of the participants have poor information, education would motivate nurses to participate actively in awareness raising, screening, and management. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=knowledge" title=" knowledge"> knowledge</a>, <a href="https://publications.waset.org/abstracts/search?q=attitude" title=" attitude"> attitude</a>, <a href="https://publications.waset.org/abstracts/search?q=screening" title=" screening"> screening</a> </p> <a href="https://publications.waset.org/abstracts/26040/knowledge-and-attitude-of-final-year-undergraduate-nursing-students-towards-prevention-of-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26040.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">452</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">220</span> Cervical Cerclage and Neonatal Death</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zinah%20Jabbar%20Mohammed%20Alrubaye">Zinah Jabbar Mohammed Alrubaye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: The purpose of this study was to compare the efficacy of prophylactic and rescue cervical cerclages for pregnant patients with an incompetent cervix, and to assess the neonatal outcomes of both clinical conditions. Methods: This was a retrospective observational study of all women who had an elective or rescue cerclage between January 2008 and December 2016 in our hospital .Prophylactic cerclage was defined as a cerclage before 16 weeks of gestation, while rescue cerclages were performed between 16 and 23 weeks of gestation. Results: In total, we analyzed the outcomes of 212 cervical interventions; 71% of the recruited patients experienced prophylactic cerclage, while 29% underwent rescue cerclage. Most of the patients delivered vaginally (70%) and were able to leave the hospital with a healthy newborn (78%). The mean pregnancy prolongation time after cerclage in the prophylactic and rescue groups were 21 weeks and 10 weeks, respectively. Conclusion: Prophylactic cerclage interventions are most likely to be associated with a reduction of fetal demise because of the correlation between fetal prognosis and the gestational age at which cerclage is performed. Once the diagnosis of cervical insufficiency is confirmed, cerclage should be recommended as this will help to prolong the pregnancy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical" title="cervical">cervical</a>, <a href="https://publications.waset.org/abstracts/search?q=neonate" title=" neonate"> neonate</a>, <a href="https://publications.waset.org/abstracts/search?q=cerclage" title=" cerclage"> cerclage</a>, <a href="https://publications.waset.org/abstracts/search?q=Cervix" title=" Cervix"> Cervix</a> </p> <a href="https://publications.waset.org/abstracts/183092/cervical-cerclage-and-neonatal-death" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183092.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">54</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">219</span> Role of P53 Codon 72 Polymorphism and Mir-146a Rs2910164 Polymorphism in Cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Rassi">Hossein Rassi</a>, <a href="https://publications.waset.org/abstracts/search?q=Marjan%20Moradi%20Fard"> Marjan Moradi Fard</a>, <a href="https://publications.waset.org/abstracts/search?q=Masoud%20Houshmand"> Masoud Houshmand </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Cervical cancer is multistep disease that is thought to result from an interaction between genetic background and environmental factors. Human papillomavirus (HPV) infection is the leading risk factor for cervical intraepithelial neoplasia (CIN) and cervical cancer. In other hand, some of p53 and miRNA polymorphism may plays an important role in carcinogenesis. This study attempts to clarify the relation of p53 genotypes and miR-146a rs2910164 polymorphism in cervical lesions. Method: Forty two archival samples with cervical lesion retired from Khatam hospital and 40 sample from healthy persons used as control group. A simple and rapid method was used to detect the simultaneous amplification of the HPV consensus L1 region and HPV-16,-18, -11, -31, 33 and -35 along with the b-globin gene as an internal control. We use Multiplex PCR for detection of P53 and miR-146a rs2910164 genotypes in our lab. Finally, data analysis was performed using the 7 version of the Epi Info(TM) 2012 software and test chi-square(x2) for trend. Results: Cervix lesions were collected from 42 patients with Squamous metaplasia, cervical intraepithelial neoplasia, and cervical carcinoma. Successful DNA extraction was assessed by PCR amplification of b-actin gene (99bp). According to the results, p53 GG genotype and miR-146a rs2910164 CC genotype was significantly associated with increased risk of cervical lesions in the study population. In this study, we detected 13 HPV 18 from 42 cervical cancer. Conclusion: The connection between several SNP polymorphism and human virus papilloma in rare researches were seen. The reason of these differences in researches' findings can result in different kinds of races and geographic situations and also differences in life grooves in every region. The present study provided preliminary evidence that a p53 GG genotype and miR-146a rs2910164 CC genotype may effect cervical cancer risk in the study population, interacting synergistically with HPV 18 genotype. Our results demonstrate that the testing of p53 codon 72 polymorphism genotypes and miR-146a rs2910164 polymorphism genotypes in combination with HPV18 can serve as major risk factors in the early identification of cervical cancers. Furthermore, the results indicate the possibility of primary prevention of cervical cancer by vaccination against HPV18 in Iran. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=HPV18" title=" HPV18"> HPV18</a>, <a href="https://publications.waset.org/abstracts/search?q=p53%20codon%2072%20polymorphism" title=" p53 codon 72 polymorphism"> p53 codon 72 polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=miR-146a%20rs2910164%20polymorphism" title=" miR-146a rs2910164 polymorphism"> miR-146a rs2910164 polymorphism</a> </p> <a href="https://publications.waset.org/abstracts/27790/role-of-p53-codon-72-polymorphism-and-mir-146a-rs2910164-polymorphism-in-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27790.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">456</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">218</span> Cervical Ectopic Pregnancy Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Berrak%20Yildiz">Berrak Yildiz</a>, <a href="https://publications.waset.org/abstracts/search?q=Hinal%20Shah"> Hinal Shah</a>, <a href="https://publications.waset.org/abstracts/search?q=Justine%20Fernandez"> Justine Fernandez</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazje%20James"> Nazje James</a>, <a href="https://publications.waset.org/abstracts/search?q=Anna%20Brown"> Anna Brown</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical ectopic pregnancy, a rare type of ectopic pregnancies, is defined by blastocyst implantation within the cervical canal rather than the endometrium. Its rarity and potential for severe hemorrhage make cervical ectopic pregnancy a diagnostic and therapeutic challenge. A 39-year-old woman, G5P2022, with a history of two cesarean sections and two elective terminations, presented to the emergency department with vaginal bleeding and pelvic pain. Initial assessment showed a beta-hCG level of 2,853 mIU/mL, and transvaginal ultrasound revealed a small, irregular gestational sac at the level of the internal cervical os. Serial betahCG measurements over subsequent visits showed a declining trend, consistent with a nonviable pregnancy. The patient was ultimately treated with methotrexate at a dose of 50 mg/m² (total 100 mg), following which she reported no further symptoms. On follow-up, her beta-hCG level returned to the normal non-pregnant range, with no additional intervention needed. This case highlights the importance of early diagnosis in cervical ectopic pregnancy to avoid complications like hysterectomy. Methotrexate is an effective first-line treatment in hemodynamically stable patients, offering a conservative approach that can preserve fertility. The success in this patient underscores the role of prompt diagnosis and careful management in achieving resolution while minimizing invasive procedures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=beta-hCG" title="beta-hCG">beta-hCG</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical" title=" cervical"> cervical</a>, <a href="https://publications.waset.org/abstracts/search?q=ectopic" title=" ectopic"> ectopic</a>, <a href="https://publications.waset.org/abstracts/search?q=methotrexate" title=" methotrexate"> methotrexate</a> </p> <a href="https://publications.waset.org/abstracts/193841/cervical-ectopic-pregnancy-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193841.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">11</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">217</span> The Effects of Highly Active Antiretroviral Therapy (HAART) on the Expression of Muc1 and P65 in a Cervical Cancer Cell Line, HCS-2</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20R.%20Thabethe">K. R. Thabethe</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20A.%20Adefolaju"> G. A. Adefolaju</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20J.%20Hosie"> M. J. Hosie</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical cancer is the third most commonly diagnosed cancer globally and it is one of three AIDS defining malignancies. Highly active antiretroviral therapy (HAART) is a combination of three or more antiretroviral drugs and has been shown to play a significant role in reducing the incidence of some AIDS defining malignancies, although its effect on cervical cancer is still unclear. The aim of this study was to investigate the relationship between cervical cancer and HAART. This was achieved by studying the expression of two signalling molecules expressed in cervical cancer; MUC1 and P65. Following the 24 hour treatment of a cervical cancer cell line, HCS-2, with drugs which are commonly used as part of HAART at their clinical plasma concentrations, real-time qPCR and immunofluorescence were used in order to study gene and protein expression. A one way ANOVA followed by a Tukey Kramer Post Hoc test was conducted using JMP 11 software on both sets of data. The drug classified as a protease inhibitor (PI) (i.e. LPV/r) reduced MUC1 and P65 gene and protein expression more than the other drug tested. PIs are known to play a significant role in cell death, therefore the cells were thought to be more susceptible to cell death following treatment with PIs. In conclusion, the drugs used, especially the PI showed some anticancer effects by facilitating cell death through decreased gene and protein expression of MUC1 and P65 and present promising agents for cancer treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=haart" title=" haart"> haart</a>, <a href="https://publications.waset.org/abstracts/search?q=MUC1" title=" MUC1"> MUC1</a>, <a href="https://publications.waset.org/abstracts/search?q=P65" title=" P65"> P65</a> </p> <a href="https://publications.waset.org/abstracts/41304/the-effects-of-highly-active-antiretroviral-therapy-haart-on-the-expression-of-muc1-and-p65-in-a-cervical-cancer-cell-line-hcs-2" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41304.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">333</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">216</span> Investigation Two Polymorphism of hTERT Gene (Rs 2736098 and Rs 2736100) and miR- 146a rs2910164 Polymorphism in Cervical Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Rassi">Hossein Rassi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaheh%20Gholami%20Roud-Majany"> Alaheh Gholami Roud-Majany</a>, <a href="https://publications.waset.org/abstracts/search?q=Zahra%20Razavi"> Zahra Razavi</a>, <a href="https://publications.waset.org/abstracts/search?q=Massoud%20Hoshmand"> Massoud Hoshmand </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical cancer is multi step disease that is thought to result from an interaction between genetic background and environmental factors. Human papillomavirus (HPV) infection is the leading risk factor for cervical intraepithelial neoplasia (CIN)and cervical cancer. In other hand, some of hTERT and miRNA polymorphism may plays an important role in carcinogenesis. This study attempts to clarify the relation of hTERT genotypes and miR-146a genotypes in cervical cancer. Forty two archival samples with cervical lesion retired from Khatam hospital and 40 sample from healthy persons used as control group. A simple and rapid method was used to detect the simultaneous amplification of the HPV consensus L1 region and HPV-16,-18, -11, -31, 33 and -35 along with the b-globin gene as an internal control. We use Multiplex PCR for detection of hTERT and miR-146a rs2910164 genotypes in our lab. Finally, data analysis was performed using the 7 version of the Epi Info(TM) 2012 software and test chi-square(x2) for trend. Cervix lesions were collected from 42 patients with Squamous metaplasia, cervical intraepithelial neoplasia, and cervical carcinoma. Successful DNA extraction was assessed by PCR amplification of b-actin gene (99bp). According to the results, hTERT ( rs 2736098) GG genotype and miR-146a rs2910164 CC genotype was significantly associated with increased risk of cervical cancer in the study population. In this study, we detected 13 HPV 18 from 42 cervical cancer. The connection between several SNP polymorphism and human virus papilloma in rare researches were seen. The reason of these differences in researches' findings can result in different kinds of races and geographic situations and also differences in life grooves in every region. The present study provided preliminary evidence that a p53 GG genotype and miR-146a rs2910164 CC genotype may effect cervical cancer risk in the study population, interacting synergistically with HPV 18 genotype. Our results demonstrate that the testing of hTERT rs 2736098 genotypes and miR-146a rs2910164 genotypes in combination with HPV18 can serve as major risk factors in the early identification of cervical cancers. Furthermore, the results indicate the possibility of primary prevention of cervical cancer by vaccination against HPV18 in Iran. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=polymorphism%20of%20hTERT%20gene" title="polymorphism of hTERT gene">polymorphism of hTERT gene</a>, <a href="https://publications.waset.org/abstracts/search?q=miR-146a%20rs2910164%20polymorphism" title=" miR-146a rs2910164 polymorphism"> miR-146a rs2910164 polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title=" cervical cancer"> cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=virus" title=" virus"> virus</a> </p> <a href="https://publications.waset.org/abstracts/28545/investigation-two-polymorphism-of-htert-gene-rs-2736098-and-rs-2736100-and-mir-146a-rs2910164-polymorphism-in-cervical-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28545.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">321</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=cervical%20lymphadenopathy&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=cervical%20lymphadenopathy&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=cervical%20lymphadenopathy&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=cervical%20lymphadenopathy&page=5">5</a></li> 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