Webinar Recap: Generics and Biosimilars in MS Treatment

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src="https://msnursepro.org/storage/articles/557-webinar-recap-generics-and-biosimilars-in-ms-treatment-img.png" alt="Webinar Recap: Generics and Biosimilars in MS Treatment" srcset="https://msnursepro.org/ip/1000/storage/articles/557-webinar-recap-generics-and-biosimilars-in-ms-treatment-img.png 1000w, https://msnursepro.org/ip/2000/storage/articles/557-webinar-recap-generics-and-biosimilars-in-ms-treatment-img.png 2000w" data-auto-dimensions="true"> </div> <div class="col-12"> <h1>Webinar Recap: Generics and Biosimilars in MS Treatment</h1> <div class="row small"> <div class="col-md-4"> <div class="d-flex align-items-center"> <svg xmlns="http://www.w3.org/2000/svg" width="15" preserveAspectRatio fill="currentColor" viewBox="0 0 24 24"><path d="M19 3H18V1H16V3H8V1H6V3H5C3.89 3 3 3.9 3 5V19C3 20.11 3.9 21 5 21H19C20.11 21 21 20.11 21 19V5C21 3.9 20.11 3 19 3M19 19H5V9H19V19M19 7H5V5H19V7Z" /></svg> <span class="ms-1"></span> </div> </div> <div class="col-md-4"> <div class="d-flex align-items-center justify-content-center"> <svg xmlns="http://www.w3.org/2000/svg" width="15" preserveAspectRatio fill="currentColor" viewBox="0 0 24 24"><path d="M12,4A4,4 0 0,1 16,8A4,4 0 0,1 12,12A4,4 0 0,1 8,8A4,4 0 0,1 12,4M12,6A2,2 0 0,0 10,8A2,2 0 0,0 12,10A2,2 0 0,0 14,8A2,2 0 0,0 12,6M12,13C14.67,13 20,14.33 20,17V20H4V17C4,14.33 9.33,13 12,13M12,14.9C9.03,14.9 5.9,16.36 5.9,17V18.1H18.1V17C18.1,16.36 14.97,14.9 12,14.9Z" /></svg><span class="ms-1">Karolina Kowalska</span> </div> </div> <div class="col-md-4"> <div class="d-flex justify-content-end"> <div class="d-flex align-items-center"><svg xmlns="http://www.w3.org/2000/svg" width="15" preserveAspectRatio fill="currentColor" viewBox="0 0 24 24"><path d="M12,9A3,3 0 0,1 15,12A3,3 0 0,1 12,15A3,3 0 0,1 9,12A3,3 0 0,1 12,9M12,4.5C17,4.5 21.27,7.61 23,12C21.27,16.39 17,19.5 12,19.5C7,19.5 2.73,16.39 1,12C2.73,7.61 7,4.5 12,4.5M3.18,12C4.83,15.36 8.24,17.5 12,17.5C15.76,17.5 19.17,15.36 20.82,12C19.17,8.64 15.76,6.5 12,6.5C8.24,6.5 4.83,8.64 3.18,12Z" /></svg> <span class="ms-1">76</span></div> </div> </div> </div> </div> </div> </div> <div class="mt-3"> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d84e351-0500-4c6b-aaae-c8560c5bfc04"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><p>On <strong>20 November 2024</strong>, MS Nurse PRO hosted an engaging webinar, <strong>Generics and Biosimilars in the Treatment of Multiple Sclerosis (MS)</strong>, featuring expert speakers Piet Eelen and Amy Perrin Ross.</p><p>The session offered valuable insights into the role of generics and biosimilars in MS care, with a focus on the nursing perspective.</p></div> </div> </section> <section data-block="9b7fadb6-f05a-4a92-a9eb-0882d3a6067d" data-id="9d92b9d9-4c5f-4a06-b62a-8a1850f3d81f" class="" style="margin-top: 0px; margin-bottom: 0px; padding-top: 15px; padding-bottom: 15px; background-color: transparent;" data-data-guid="9d8c7706-32d7-446f-88ac-2fbba8e4ca0c"> <div class="container" style="background-color: transparent;"> <div class="row gy-4"> <div class="col-lg-6 d-flex justify-content-center"> <div class="w-100"> <div class="gs-video-container mb-3"> <iframe title="youtube" src="https://www.youtube.com/embed/srM2VrNxbJk?modestbranding=1&color=white" frameborder="0" allow="accelerometer; autoplay; encrypted-media;" allowfullscreen></iframe> </div> </div> </div> <div class="col-lg-6"> <div class="w-100" data-editor="tiny-w" id="" style=""><h3><br></h3><h3 style="text-align: center;" data-mce-style="text-align: center;">Missed the Webinar? Watch the Recording!</h3><p><br></p><p>If you couldn鈥檛 join us live, don鈥檛 worry! The webinar recording will soon be available on our website. Dive into the session at your convenience and explore the practical strategies and insights shared by our expert speakers.聽 the practical strategies and insights shared by our expert speakers.</p></div> </div> </div> </div> </section> <section data-block="9b89208c-a48a-47f2-8260-96428760d5d6" data-id="9d88b5a2-5cf1-4f22-aa95-2f8af39d21e7" class="" style="margin-top: 0px; margin-bottom: 0px; padding-top: 15px; padding-bottom: 15px; background-color: transparent;"> <div class="container" style="background-color: transparent;"> <div class="row g-5"> <div class="col-lg-6 d-flex justify-content-center"> <div style="max-width: 500px; position:relative;"> <picture> <source media="(max-width: 600px)" srcset="/ip/250/storage/761-placeholder.png"> <source media="(min-width: 601px)" srcset="/ip/500/storage/761-placeholder.png"> <img src="/ip/500/storage/761-placeholder.png" alt="placeholder" data-auto-dimensions="true"> </picture> </div> </div> <div class="col-lg-6"> <div data-editor="tiny-w" id="" class="" style=""><h4 style="text-align: center;" data-mce-style="text-align: center;">The role of biosimilars and generics in the treatment of MS</h4><p>Amy Perrin Ross, APN, MSN, CNRN, MSCN, explained the key <strong>differences</strong> between <strong>biosimilars and generics</strong>, outlined their regulatory pathways, and discussed their cost implications in managing MS, one of the most expensive chronic conditions to treat. The presentation emphasised the <strong>clinical equivalence of biosimilars to branded biologics</strong> and explored the <strong>concept of interchangeability</strong>, addressing both benefits and risks.</p><p>With a focus on practical application, the session provided MS nurses with valuable knowledge to enhance patient care and optimise treatment affordability without compromising efficacy or safety.</p></div> </div> </div> </div> </section> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d88b6d2-6d87-4591-bc7b-e13c04bf361b"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><h4 style="text-align: center;" data-mce-style="text-align: center;">Key insights on the the definition and regulatory framework:</h4><ul><li><strong>Definition and characteristics of biosimilars:</strong><br>Biosimilars are highly similar to reference biologics, with no clinically meaningful differences in terms of quality, safety, or efficacy.</li><li><strong>Comparison with branded products:</strong><br>Biosimilars share the same living sources, route of administration, strength, dosage, and treatment benefits as branded biologics.</li><li><strong>Distinction between generics and biosimilars:</strong><br>Unlike generics, which are chemically synthesized, biosimilars are derived from living organisms and involve more complex manufacturing and regulatory processes.</li><li><strong>Cost implications in MS treatment:</strong><br>MS is among one of the most expensive chronic conditions to treat, with lifetime costs averaging around $5 million. Biosimilars offer a cost-effective alternative due to their abbreviated clinical trial programmes.</li><li><strong>Approval and regulatory requirements:</strong><br>Approval of biosimilars is based on the "totality of evidence," including structural, functional, pharmacokinetic, and pharmacodynamic equivalence studies.</li><li><strong>Interchangeability:</strong><br>Not all biosimilars are interchangeable. Additional regulatory requirements must be met to classify a biosimilar as interchangeable, allowing substitution without prescriber intervention.</li><li><strong>Benefits vs. risks:</strong><br>While biosimilars provide cost savings and access benefits, careful evaluation of safety, efficacy, and immunogenicity in sensitive populations is essential.</li><li><strong>Impact on care of people with MS:</strong><br>The adoption of biosimilars could reduce treatment costs, improving accessibility while maintaining treatment efficacy.</li></ul><p><br></p></div> </div> </section> <section data-block="9b89208c-a48a-47f2-8260-96428760d5d6" data-id="9d84f2c4-be07-498b-8271-4ef9f1b4a0ce" class="" style="margin-top: 0px; margin-bottom: 0px; padding-top: 14px; padding-bottom: 15px; background-color: transparent;"> <div class="container" style="background-color: transparent;"> <div class="row g-5"> <div class="col-lg-6 d-flex justify-content-center"> <div style="max-width: 500px; position:relative;"> <picture> <source media="(max-width: 600px)" srcset="/ip/250/storage/938-placeholder.png"> <source media="(min-width: 601px)" srcset="/ip/500/storage/938-placeholder.png"> <img src="/ip/500/storage/938-placeholder.png" alt="placeholder" data-auto-dimensions="true"> </picture> </div> </div> <div class="col-lg-6"> <div data-editor="tiny-w" id="" class="" style=""><h4 style="text-align: center;" data-mce-style="text-align: center;">Evolving responsibilities of MS nurses in navigating the increasingly complex treatment landscape</h4><p>Piet Eelen, RN, MSc,聽emphasised the<strong> importance of patient education</strong>, communication, and <strong>strategies </strong>for managing <strong>therapy transitions</strong>, including addressing the <strong>nocebo</strong> <strong>effect</strong> associated with biosimilars.</p><p>Piet provided examples of <strong>practical tools</strong> and approaches to support nurses in empowering patients, <strong>fostering adherence</strong>, and <strong>ensuring informed</strong>,<strong> shared decision</strong>-<strong>making.</strong> His insights reinforced the<strong> critical role of MS nurses</strong> in enhancing care quality and patient outcomes in a dynamic therapeutic environment.<br><br></p></div> </div> </div> </div> </section> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d88bd00-4d9c-4795-928e-a066ed8eab14"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><h4 style="text-align: center;" data-mce-style="text-align: center;">Key Insights on MS nurses responsibilities:</h4><ul><li><strong>Evolving role of MS nurses:</strong><br>The increasing complexity of disease-modifying therapies (DMTs) requires MS nurses to adapt their roles, emphasising patient education and communication.</li><li><strong>Treatment landscape:</strong><br>Over the past 30 years, MS treatments have advanced significantly, with the introduction of high-efficacy therapies, oral treatments, and biosimilars, adding complexity to patient management.</li><li><strong>Practical management strategies:</strong><br>MS nurses are pivotal in managing therapy switches, educating patients about their disease and treatment options, and fostering shared decision-making to improve adherence and outcomes.</li><li><strong>Nocebo effect in biosimilars:</strong><br>Negative expectations about biosimilars can reduce their acceptance and clinical benefits. Nurses can counteract this by delivering balanced information, framing positive attributes, and empowering patients.</li><li><strong>Consensus recommendations for follow-on DMTs:</strong><br>Recommendations include comprehensive education, timely reporting, ongoing pharmacovigilance, and strategies to minimise nocebo effects, promoting evidence-based decision-making and patient empowerment.</li><li><strong>Tools for nurses:</strong><br>Resources like pocket guides, lexicons, and infographics can support nurses in explaining treatment options effectively to patients.</li></ul><p><br></p></div> </div> </section> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d9482ba-5d4f-4424-9a7e-c4feae6f4cfc"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><h3 style="text-align: center;" data-mce-style="text-align: center;">Meet the speakers</h3></div> </div> </section> <section data-block="9b7f735f-bdac-49c0-9813-bf167a7b8607" data-id="9d9481a2-ab03-4989-a3ab-595e43712c61"> <div class="container"> <div style="max-width: 250px; margin-left: auto; margin-right: auto; position: relative;"> <div style="aspect-ratio: 1 / 1; overflow: hidden; width: 100%; border-radius: 900px;"> <img alt="profile" src="/ip/250/storage/516-profile.png"> </div> </div> </div> </section> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d9481ed-f714-4c70-b058-e0543f215cdc"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><h5 style="text-align: center;" data-mce-style="text-align: center;">Amy Perrin Ross<br>APN, MSN, CNRN, MSCN,<br>Loyola University Medical Center (USA)</h5><p>Amy Perrin Ross is the Neuroscience Program Coordinator at Loyola University Medical Center in Maywood, Illinois. She is the Coordinator of the MS Center at Loyola.聽</p><p>Ms. Ross earned her undergraduate and graduate degrees from Loyola University in Chicago, Illinois. She has also completed coursework for her doctoral degree at the University of Illinois Medical Center. She is board certified as a Neuroscience Nurse by the American Board of Neuroscience Nursing, and as a Multiple Sclerosis Nurse by the Multiple Sclerosis Nursing International Certification Board.</p><p>Ms. Ross is an active participant in a variety of medical societies, including the American Association of Neuroscience Nurses, the American Association of Critical Care Nurses, the Multiple Sclerosis Society, the Multiple Sclerosis Association of America, and the International Organization of Multiple Sclerosis Nurses and the Consortium of MS Centers. She is a Clinical Reviewer for the International Journal of MS Care. Her work has been published in numerous journals, including Multiple Sclerosis, Frontiers in Neurology, the International Journal of MS Care, the International Journal of Clinical Practice, Neurology, Practical Neurology and the Journal of Neuroscience Nursing. Ms. Ross has participated in more than 40 research studies and has been invited to speak before numerous national and international meetings and conferences. She has been honored for her work in the field, receiving the 2015 June Halper Award of Excellence in International MS Nursing, recognizing her for leadership and creativity in the care of people with MS and their families. 聽</p><p><br></p></div> </div> </section> <section data-block="9b7f735f-bdac-49c0-9813-bf167a7b8607" data-id="9d948233-1e7f-4f6f-b84b-fbfe8ef07e19"> <div class="container"> <div style="max-width: 250px; margin-left: auto; margin-right: auto; position: relative;"> <div style="aspect-ratio: 1 / 1; overflow: hidden; width: 100%; border-radius: 900px;"> <img alt="profile" src="/ip/250/storage/988-profile.png"> </div> </div> </div> </section> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d94823a-919a-472d-8bda-0928c6359b84"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><h5 style="text-align: center;" data-mce-style="text-align: center;">Piet Eelen<br>RN, MSc, National MS Center,<br>Belgium</h5><p>Piet Eelen is a Clinical Nurse Specialist Multiple Sclerosis working in the National Multiple Sclerosis Center (NMSC) of Melsbroek, Belgium. He has a post-bachelor degree in Rehabilitation and Continence Nursing. From 1990 until 2011 he worked as a head nurse of a rehabilitation ward. Since 2012 he works as a clinical nurse specialist guiding and supporting persons with MS in his clinical practice, with a special focus on chronic disease management and lifestyle factors in MS.</p><p>He organizes courses for nurses to stimulate development and education, in the NMSC and in Belgium. He participates and collaborates with national and international healthcare associations. He is an invited speaker and member of advisory boards organized by pharma companies. Finally he participates and organizes research projects in MS in the NMSC. Since 2012 he is the president of the Belgian Association of MS-Nurses. Since 2020 he is the chair of the syllabus committee of MS Nurse PRO.</p><p><br></p></div> </div> </section> <section data-block="9bd35b64-37bc-4b5d-91a2-ee6cd6a12140" data-id="9d84ef3f-a826-449a-91f3-b3382c6cd941"> <div class="container"> <div class="row g-5 d-flex flex-column-reverse flex-lg-row"> <div class="col-lg-6 d-flex align-items-center"> <div data-editor="tiny-w" id="" class="" style=""><p>This webinar was supported by Sandoz, with no involvement in the development of the scientific program or presentations.</p></div> </div> <div class="col-lg-6 d-flex justify-content-center align-items-center"> <div style="max-width: 500px; position:relative;"> <picture> <source media="(max-width: 600px)" srcset="/ip/250/storage/046-placeholder.png"> <source media="(min-width: 601px)" srcset="/ip/500/storage/046-placeholder.png"> <img src="/ip/500/storage/046-placeholder.png" alt="placeholder" data-auto-dimensions="true"> </picture> </div> </div> </div> </div> </section> <section data-block="9b3a56a2-f645-45de-8b16-b02b939c4f93" data-id="9d84f20d-6d28-41e2-acf6-72ce66f832c4"> <div class="container"> <div class="w-100" data-editor="tiny-w" id="" style=""><h6>About our translations</h6><p>All Blogposts, e-learning Courses, e-Newsletters, e-Newsflashes and the website content of MS Nurse PRO is originally created in English (UK).聽<br>Our Educational Read Blogposts and our e-learning courses are reviewed by our scientific committee on accuracy and objectiveness.聽<br>Next, the content is auto-translated by Microsoft Translator and made available on our platform.聽<br>The translated content is not language reviewed with the exception of our e-learning Course content.<br>MS Nurse PRO has put a process in place to have our e-learning Courses language reviewed by native speaking experts (nurses or neurologists).聽<br>We make all translated e-learning Courses available immediately and next, the language review process is started. 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