CINXE.COM

<!DOCTYPE html><html lang="en"><head><meta charSet="utf-8"/><meta name="viewport" content="width=device-width,initial-scale=1"/><meta name="robots" content="max-image-preview:large"/><title>Lumen using spirulina to make ‘edible’ antibodies - BioProcess Insider</title><meta name="description" content="Lumen Biosciences hopes to use its spirulina-based platform to develop drugs targeting gastrointestinal disorders."/><meta property="og:title" content="Lumen using spirulina to make ‘edible’ antibodies - BioProcess Insider"/><meta property="og:description" content="Lumen Biosciences hopes to use its spirulina-based platform to develop drugs targeting gastrointestinal disorders."/><meta property="og:url" content="https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"/><meta property="og:type" content="article"/><meta property="og:image" content="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt5354aa5ebeb2d982/658d74c62ef467040a88a0ed/spirulina-.jpg?disable=upscale&width=1200&height=630&fit=crop"/><meta property="oc:keywords" content="BPI Podcasts, Bioprocess Insider, Upstream & Downstream Processing"/><link rel="canonical" href="https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"/><script type="application/ld+json">{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.bioprocessintl.com"},{"@type":"ListItem","position":2,"name":"BPI Podcasts","item":"https://www.bioprocessintl.com/bioprocess-insider/bpi-podcasts"}]}</script><link rel="preload" href="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt5354aa5ebeb2d982/658d74c62ef467040a88a0ed/spirulina-.jpg?width=1280&auto=webp&quality=10&format=jpg&disable=upscale&blur=40" as="image"/><meta property="twitter:card" content="summary"/><script type="text/javascript">window.NREUM||(NREUM={});NREUM.init={distributed_tracing:{enabled:true},privacy:{cookies_enabled:true},ajax:{deny_list:["bam.eu01.nr-data.net"]}}; ;NREUM.loader_config={accountID:"3936348",trustKey:"3288925",agentID:"538600195",licenseKey:"NRJS-26ae6a3b09493bbcc87",applicationID:"538600195"}; ;NREUM.info={beacon:"bam.eu01.nr-data.net",errorBeacon:"bam.eu01.nr-data.net",licenseKey:"NRJS-26ae6a3b09493bbcc87",applicationID:"538600195",sa:1}; ;/*! For license information please see nr-loader-spa-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>u});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function u(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>g,xN:()=>p});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const u="[data-nr-mask]",d=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(u):""===t||null===t?e.mask_selector=u:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function p(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,d());const r=(0,s.nY)(e);r&&(r.init=l[e])}function g(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},u={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},d={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!d[e])throw new Error("Runtime for ".concat(e," was never set"));return d[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");d[e]={...(0,n.a)(t,u),...c},Object.hasOwnProperty.call(d[e],"harvestCount")||Object.defineProperty(d[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=d[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.274.0",i="PROD",o="CDN",a="^2.0.0-alpha.17"},6154:(e,t,r)=>{"use strict";r.d(t,{A4:()=>s,OF:()=>d,RI:()=>i,WN:()=>h,bv:()=>o,gm:()=>a,lR:()=>f,m:()=>u,mw:()=>c,sb:()=>l});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s="complete"===a?.document?.readyState,c=Boolean("hidden"===a?.document?.visibilityState),u=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),l=d&&"undefined"==typeof SharedWorker,f=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),h=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>u});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};d(e),s[e].get(t)||s[e].set(t,r)}function u(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function d(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(d(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)p(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function p(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>u});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),u=function e(t,r){var n={},s={},d={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:p,addEventListener:p,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(u.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=g(e),d=c.length,l=0;l<d;l++)c[l].apply(a,r);var p=v()[s[e]];p&&p.push([f,e,r,a]);return a},get:m,listeners:g,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function p(e,t){n[e]=g(e).concat(t)}function g(e){return n[e]||[]}function m(t){return d[t]=d[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),d=(0,n.Zm)();d.ee||(d.ee=u)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>u});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function u(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>u,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},u={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>d,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>u,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function u(e){let t=a();return t.initializedAgents?.[e]}function d(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,u="addEventListener",d="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[u,d],"-",p)}function p(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(u+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(d+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,u);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{Jt:()=>o,YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],u=e[c];d(u)||(e[c]=r(u,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return d(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){u([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,d,l;try{a=this,o=[...arguments],d="function"==typeof n?n(o,a):n||{}}catch(t){u([t,"",[o,a,s],d],e)}i(r+"start",[o,a,s],d,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],d,c),e}finally{i(r+"end",[o,a,l],d,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){u([t,r,n,i],e)}s=a}}}function u(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function d(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>u});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function u(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>d,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>u,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},u={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},d=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>u,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function u(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>u,Rz:()=>d,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,u="fn"+s,d="pushState",l=1e3},3962:(e,t,r)=>{"use strict";r.d(t,{AM:()=>o,O2:()=>s,Qu:()=>c,TZ:()=>a,ih:()=>u,tC:()=>i});var n=r(860);const i=["click","keydown","submit"],o="api",a=n.K7.softNav,s={INITIAL_PAGE_LOAD:"",ROUTE_CHANGE:1,UNSPECIFIED:2},c={INTERACTION:1,AJAX:2,CUSTOM_END:3,CUSTOM_TRACER:4},u={IP:"in progress",FIN:"finished",CAN:"cancelled"}},7378:(e,t,r)=>{"use strict";r.d(t,{$p:()=>x,BR:()=>b,Kp:()=>R,L3:()=>y,Lc:()=>c,NC:()=>o,SG:()=>d,TZ:()=>i,U6:()=>p,UT:()=>m,d3:()=>w,dT:()=>f,e5:()=>A,gx:()=>v,l9:()=>l,oW:()=>h,op:()=>g,rw:()=>u,tH:()=>E,uP:()=>s,wW:()=>T,xq:()=>a});var n=r(384);const i=r(860).K7.spa,o=["click","submit","keypress","keydown","keyup","change"],a=999,s="fn-start",c="fn-end",u="cb-start",d="api-ixn-",l="remaining",f="interaction",h="spaNode",p="jsonpNode",g="fetch-start",m="fetch-done",v="fetch-body-",b="jsonp-end",y=(0,n.dV)().o.ST,w="-start",R="-end",x="-body",T="cb"+R,A="jsTime",E="fetch"},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>j});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),u=r(5289),d=r(6154),l=r(944),f=r(3969),h=r(384),p=r(6344);const g=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",p.G4.RECORD,p.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),w=r(3785),R=r(2646),x=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,x.YM)(i),a=new R.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();g.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),N=r(5603),O=r(5284);const _=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function j(e,t={},g,R){let{init:x,info:j,loader_config:P,runtime:C={},exposed:k=!0}=t;C.loaderType=g;const L=(0,h.pV)();j||(x=L.init,j=L.info,P=L.loader_config),(0,S.xN)(e.agentIdentifier,x||{}),(0,N.a)(e.agentIdentifier,P||{}),j.jsAttributes??={},d.bv&&(j.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,j);const H=(0,S.D0)(e.agentIdentifier),D=[j.beacon,j.errorBeacon];I||(H.proxy.assets&&(_(H.proxy.assets),D.push(H.proxy.assets)),H.proxy.beacon&&D.push(H.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===H.soft_navigations.enabled&&H.feature_flags.includes("soft_nav")),C.denyList=[...H.ajax.deny_list||[],...H.ajax.block_internal?D:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const g={};var R=s.ee.get(e),x=R.get("tracer");E[e]=b.g.OFF,R.on(p.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function N(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}g.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,R),(0,w.R)(R,e,t,r)},g.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,R),T(R,e,t,{customAttributes:r,level:i})},m.forEach((e=>{g[e]=I(A,e,!0,"api")})),g.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),g.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},g.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return N(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},g.setUserId=function(e){if("string"==typeof e||null===e)return N("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},g.setApplicationVersion=function(e){if("string"==typeof e||null===e)return N("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},g.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,R),R.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},g[p.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.RECORD,[],void 0,n.K7.sessionReplay,R)},g[p.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.PAUSE,[],void 0,n.K7.sessionReplay,R)},g.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const _=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,R),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,R),function(){if(x.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw x.emit("fn-err",[arguments,this,t],r),t}finally{x.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,R),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,R),r?void 0:this}}function j(){r.e(478).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),R.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{_[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),g.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),g.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,R),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,R)},d.RI?(0,u.GG)((()=>j()),!0):j(),g}(e.agentIdentifier,R,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({212:"nr-spa-compressor",249:"nr-spa-recorder",478:"nr-spa"}[e]+"-1.274.0.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var u=document.getElementsByTagName("script"),d=0;d<u.length;d++){var l=u[d];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={478:"sha512-1vUqEfJPB8Pihje9mv5CfYgkitO1FWcS+UQb84DbXqP8oYctRv4/lzl/MzNLPlRhcY1WVDBGL20I8vm6s2VV7g==",249:"sha512-Y/BeZAh6VSTmUtUNmS5XdyKxL92s30Fyyj8xVW76HSPxcKItL4+x2+kGMZc8pMJnUpZDz1L4eftZQAJh3D8NnA==",212:"sha512-Gn2tQ3qog5Yhrx/gRutkSTYPp+7nkKFt4/mIXg99LxcNpMDAYJZDBYmAACdoHNM86+iq1F3cBcQotFNzjIX8bw=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(p);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},p=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={38:0,788:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,u=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);u<a.length;u++)o=a[u],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function u(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var d=i(425);var l=i(1687),f=i(4234),h=i(5289),p=i(6154),g=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(478).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(478).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(478).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};p.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,g.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class w extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var R=i(384);var x=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class N extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),p.RI&&((0,T.u)((()=>(0,x.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,x.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class _ extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),j=i(3304);class P{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,j.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return H(e)?e:new P(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(H(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function L(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new P(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return H(e.error)?e.error:C(e)}function H(e){return e instanceof Error&&!!e.stack}class D extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,x.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),p.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,x.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),p.gm.addEventListener("error",(e=>{this.abortHandler&&(0,x.p)("err",[L(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var M=i(8990);let K=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===p.gm?0:(0,M.I)(e,U,(function(){return K++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,j.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=p.gm.XMLHttpRequest,a=p.gm.MutationObserver,s=p.gm.Promise,c=p.gm.setInterval,u="readystatechange",d=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=p.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(u,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,d,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(g?g.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var g=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===u||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",J=["arrayBuffer","blob","json","text","formData"],Q=p.gm.Request,ee=p.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(Q&&ee&&p.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,J.forEach((e=>{r(Q[te],e,X),r(ee[te],e,X)})),r(p.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),u={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(u.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),u.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(u.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),u}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof p.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,j.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),ue=["load","error","abort","timeout"],de=ue.length,le=(0,R.dV)().o.REQ,fe=(0,R.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,x.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};p.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};pe(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=R,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),p.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},pe(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<de;s++)r.addEventListener(ue[s],this.listener,(0,A.jT)(!1))}function u(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function d(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function g(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&p.RI&&(t=""+p.gm.location.href):e[0]&&e[0].url?t=e[0].url:p.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:p.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),pe(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function w(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function R(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<de;t++)e.removeEventListener(ue[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,x.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",u),t.on("xhr-load-added",d),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",g),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",w)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function pe(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const ge={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!p.RI||ge[t.debugId]++||(ge[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:we,d3:Re,Kp:xe,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class Ne extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,x.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+Re,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+xe,(function(e){(0,x.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,x.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:we,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class _e extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,g.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,x.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,g.Aw)(this.agentIdentifier)}#u=!1;async#c(e){if(!this.#u){this.#u=!0;try{const{Recorder:t}=await Promise.all([i.e(478),i.e(249)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3962);class je extends b{static featureName=Ie.TZ;constructor(e,t=!0){if(super(e,Ie.TZ,t),!p.RI||!(0,R.dV)().o.MO)return;const r=ve(this.ee);Ie.tC.forEach((e=>{(0,A.sp)(e,(e=>{a(e)}),!0)}));const n=()=>(0,x.p)("newURL",[(0,S.t)(),""+window.location],void 0,this.featureName,this.ee);r.on("pushState-end",n),r.on("replaceState-end",n);try{this.removeOnAbort=new AbortController}catch(e){}(0,A.sp)("popstate",(e=>(0,x.p)("newURL",[e.timeStamp,""+window.location],void 0,this.featureName,this.ee)),!0,this.removeOnAbort?.signal);let i=!1;const o=new((0,R.dV)().o.MO)(((e,t)=>{i||(i=!0,requestAnimationFrame((()=>{(0,x.p)("newDom",[(0,S.t)()],void 0,this.featureName,this.ee),i=!1})))})),a=(0,v.s)((e=>{(0,x.p)("newUIEvent",[e],void 0,this.featureName,this.ee),o.observe(document.body,{attributes:!0,childList:!0,subtree:!0,characterData:!0})}),100,{leading:!0});this.abortHandler=function(){this.removeOnAbort?.abort(),o.disconnect(),this.abortHandler=void 0},this.importAggregator(e,{domObserver:o})}}var Pe=i(7378);const Ce={},ke=["appendChild","insertBefore","replaceChild"];function Le(e){const t=function(e){return(e||B.ee).get("jsonp")}(e);if(!p.RI||Ce[t.debugId])return t;Ce[t.debugId]=!0;var r=(0,W.YM)(t),n=/[?&](?:callback|cb)=([^&#]+)/,i=/(.*)\.([^.]+)/,o=/^(\w+)(\.|$)(.*)$/;function a(e,t){if(!e)return t;const r=e.match(o),n=r[1];return a(r[3],t[n])}return r.inPlace(Node.prototype,ke,"dom-"),t.on("dom-start",(function(e){!function(e){if(!e||"string"!=typeof e.nodeName||"script"!==e.nodeName.toLowerCase())return;if("function"!=typeof e.addEventListener)return;var o=(s=e.src,c=s.match(n),c?c[1]:null);var s,c;if(!o)return;var u=function(e){var t=e.match(i);if(t&&t.length>=3)return{key:t[2],parent:a(t[1],window)};return{key:e,parent:window}}(o);if("function"!=typeof u.parent[u.key])return;var d={};function l(){t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}function f(){t.emit("jsonp-error",[],d),t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}r.inPlace(u.parent,[u.key],"cb-",d),e.addEventListener("load",l,(0,A.jT)(!1)),e.addEventListener("error",f,(0,A.jT)(!1)),t.emit("new-jsonp",[e.src],d)}(e[0])})),t}const He={};function De(e){const t=function(e){return(e||B.ee).get("promise")}(e);if(He[t.debugId])return t;He[t.debugId]=!0;var r=t.context,n=(0,W.YM)(t),i=p.gm.Promise;return i&&function(){function e(r){var o=t.context(),a=n(r,"executor-",o,null,!1);const s=Reflect.construct(i,[a],e);return t.context(s).getCtx=function(){return o},s}p.gm.Promise=e,Object.defineProperty(e,"name",{value:"Promise"}),e.toString=function(){return i.toString()},Object.setPrototypeOf(e,i),["all","race"].forEach((function(r){const n=i[r];e[r]=function(e){let i=!1;[...e||[]].forEach((e=>{this.resolve(e).then(a("all"===r),a(!1))}));const o=n.apply(this,arguments);return o;function a(e){return function(){t.emit("propagate",[null,!i],o,!1,!1),i=i||!e}}}})),["resolve","reject"].forEach((function(r){const n=i[r];e[r]=function(e){const r=n.apply(this,arguments);return e!==r&&t.emit("propagate",[e,!0],r,!1,!1),r}})),e.prototype=i.prototype;const o=i.prototype.then;i.prototype.then=function(...e){var i=this,a=r(i);a.promise=i,e[0]=n(e[0],"cb-",a,null,!1),e[1]=n(e[1],"cb-",a,null,!1);const s=o.apply(this,e);return a.nextPromise=s,t.emit("propagate",[i,!0],s,!1,!1),s},i.prototype.then[W.Jt]=o,t.on("executor-start",(function(e){e[0]=n(e[0],"resolve-",this,null,!1),e[1]=n(e[1],"resolve-",this,null,!1)})),t.on("executor-err",(function(e,t,r){e[1](r)})),t.on("cb-end",(function(e,r,n){t.emit("propagate",[n,!0],this.nextPromise,!1,!1)})),t.on("propagate",(function(e,r,n){this.getCtx&&!r||(this.getCtx=function(){if(e instanceof Promise)var r=t.context(e);return r&&r.getCtx?r.getCtx():this})}))}(),t}const Me={},Ke="setTimeout",Ue="setInterval",Ve="clearTimeout",Ge="-start",Fe=[Ke,"setImmediate",Ue,Ve,"clearImmediate"];function Be(e){const t=function(e){return(e||B.ee).get("timer")}(e);if(Me[t.debugId]++)return t;Me[t.debugId]=1;var r=(0,W.YM)(t);return r.inPlace(p.gm,Fe.slice(0,2),Ke+"-"),r.inPlace(p.gm,Fe.slice(2,3),Ue+"-"),r.inPlace(p.gm,Fe.slice(3),Ve+"-"),t.on(Ue+Ge,(function(e,t,n){e[0]=r(e[0],"fn-",null,n)})),t.on(Ke+Ge,(function(e,t,n){this.method=n,this.timerDuration=isNaN(e[1])?0:+e[1],e[0]=r(e[0],"fn-",this,n)})),t}const We={};function ze(e){const t=function(e){return(e||B.ee).get("mutation")}(e);if(!p.RI||We[t.debugId])return t;We[t.debugId]=!0;var r=(0,W.YM)(t),n=p.gm.MutationObserver;return n&&(window.MutationObserver=function(e){return this instanceof n?new n(r(e,"fn-")):n.apply(this,arguments)},MutationObserver.prototype=n.prototype),t}const{TZ:qe,d3:Ze,Kp:Ye,$p:Xe,wW:Je,e5:Qe,tH:$e,uP:et,rw:tt,Lc:rt}=Pe;class nt extends b{static featureName=qe;constructor(e,t=!0){if(super(e,qe,t),!p.RI)return;try{this.removeOnAbort=new AbortController}catch(e){}let r,n=0;const i=this.ee.get("tracer"),o=Le(this.ee),a=De(this.ee),s=Be(this.ee),c=Z(this.ee),u=this.ee.get("events"),d=ne(this.ee),l=ve(this.ee),f=ze(this.ee);function h(e,t){l.emit("newURL",[""+window.location,t])}function g(){n++,r=window.location.hash,this[et]=(0,S.t)()}function m(){n--,window.location.hash!==r&&h(0,!0);var e=(0,S.t)();this[Qe]=~~this[Qe]+e-this[et],this[rt]=e}function v(e,t){e.on(t,(function(){this[t]=(0,S.t)()}))}this.ee.on(et,g),a.on(tt,g),o.on(tt,g),this.ee.on(rt,m),a.on(Je,m),o.on(Je,m),this.ee.on("fn-err",((...t)=>{t[2]?.__newrelic?.[e.agentIdentifier]||(0,x.p)("function-err",[...t],void 0,this.featureName,this.ee)})),this.ee.buffer([et,rt,"xhr-resolved"],this.featureName),u.buffer([et],this.featureName),s.buffer(["setTimeout"+Ye,"clearTimeout"+Ze,et],this.featureName),c.buffer([et,"new-xhr","send-xhr"+Ze],this.featureName),d.buffer([$e+Ze,$e+"-done",$e+Xe+Ze,$e+Xe+Ye],this.featureName),l.buffer(["newURL"],this.featureName),f.buffer([et],this.featureName),a.buffer(["propagate",tt,Je,"executor-err","resolve"+Ze],this.featureName),i.buffer([et,"no-"+et],this.featureName),o.buffer(["new-jsonp","cb-start","jsonp-error","jsonp-end"],this.featureName),v(d,$e+Ze),v(d,$e+"-done"),v(o,"new-jsonp"),v(o,"jsonp-end"),v(o,"cb-start"),l.on("pushState-end",h),l.on("replaceState-end",h),window.addEventListener("hashchange",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("load",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("popstate",(function(){h(0,n>1)}),(0,A.jT)(!0,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var it=i(3333);class ot extends b{static featureName=it.TZ;constructor(e,t=!0){super(e,it.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];p.RI&&e.init.user_actions.enabled&&(it.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),it.qN.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var at=i(993),st=i(3785);class ct extends b{static featureName=at.TZ;constructor(e,t=!0){super(e,at.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,st.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),p.gm?(this.features={},(0,R.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(w),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,d.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=u(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,R.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[he,w,N,Ne,_e,_,D,ot,ct,je,nt],loaderType:"spa"})})()})(); </script><link rel="preconnect" href="https://cdn.cookielaw.org"/><link rel="preconnect" href="https://fonts.gstatic.com" crossorigin="anonymous"/><link rel="preconnect" href="https://fonts.googleapis.com" crossorigin="anonymous"/><link rel="preconnect" href="https://www.googletagmanager.com"/><link rel="stylesheet" href="/build/_assets/styles.generated-IVZR5GKI.css"/><link rel="stylesheet" href="/build/_assets/brand.generated-PMJMGHVW.css"/><link rel="stylesheet" href="https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,500;0,600;0,700;0,800;1,300;1,400;1,500;1,600;1,700;1,800&display=swap"/><link rel="stylesheet" href="https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,500;0,600;0,700;0,800;1,300;1,400;1,500;1,600;1,700;1,800&display=swap"/><link rel="icon" type="image/x-icon" href="/build/_assets/bioprocessinternational-XJK2Q5PK.ico"/><script type="text/javascript" src="https://cdn.cookielaw.org/consent/c0c70deb-8acc-4a4e-901a-bb865dd8f587/OtAutoBlock.js"></script><script type="text/javascript" src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" data-domain-script="c0c70deb-8acc-4a4e-901a-bb865dd8f587"></script><script> function OptanonWrapper() { const isClosed = OneTrust.IsAlertBoxClosed() const allowPersonalised = /,C0004,/.test(OnetrustActiveGroups) console.log('cookieBannerConsentChanged emit', isClosed, allowPersonalised) const event = new CustomEvent('cookieBannerConsentChanged', { detail: { allowPersonalised, isClosed } }) window.dispatchEvent(event) }</script><script async="" src="https://securepubads.g.doubleclick.net/tag/js/gpt.js" type="text/javascript"></script><link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/font-awesome/4.7.0/css/font-awesome.min.css"/><link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/bootstrap-icons@1.3.0/font/bootstrap-icons.css"/></head><body class="brand-bioprocessinternational "><noscript></noscript><div id="bigsky_v"></div><div id="fb-root"></div><main data-theme="theme1" class="Provider"><div data-testid="ad_blocker" class="ads ad adsbox doubleclick ad-placement carbon-ads" style="height:1px;width:1px;position:absolute;left:-999em;top:-999em"></div><div><div data-template="layout" class="Layout"><nav data-module="navigation" aria-label="navigation" class="Navigation"><div data-testid="header" class="Navigation-HeaderWrapper"><div class="FullScreenBackground Navigation-HeaderBackground"></div><div class="Navigation-Header"><div class="InformaBar" data-component="informa-bar"><div class="InformaBar-ContentSection InformaBar-ContentSection_hidden" data-testid="informa-bar-content-section"><div class="InformaBar-LeftSection" data-testid="informa-bar-left-section"><div>BioProcess International is part of the Informa Connect Division of Informa PLC</div><div><a class="InformaBar-SubMenuItem" data-testid="informa-bar-sub-menu-item" href="https://www.informa.com/" title="Informa PLC" target="_blank" rel="noreferrer">Informa PLC</a><span class="InformaBar-Delimiter">|</span><a class="InformaBar-SubMenuItem" data-testid="informa-bar-sub-menu-item" href="https://www.informa.com/about-us/" title="ABOUT US" target="_blank" rel="noreferrer">ABOUT US</a><span class="InformaBar-Delimiter">|</span><a class="InformaBar-SubMenuItem" data-testid="informa-bar-sub-menu-item" href="https://www.informa.com/investors/" title="INVESTOR RELATIONS" target="_blank" rel="noreferrer">INVESTOR RELATIONS</a><span class="InformaBar-Delimiter">|</span><a class="InformaBar-SubMenuItem" data-testid="informa-bar-sub-menu-item" href="https://www.informa.com/talent/" title="TALENT" target="_blank" rel="noreferrer">TALENT</a></div></div><div class="InformaBar-RightSection" data-testid="informa-bar-right-section">This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.</div></div><div class="InformaBar-LogoSection" data-testid="informa-bar-logo-section" role="button" tabindex="0" aria-label="Open Informa bar"><div class="InformaBar-LogoWrapper"><img class="InformaBar-Logo" src="/build/_assets/informaLogoWhite-RZAE7EJI.png" alt="Logo Informa"/></div><span class="InformaBar-IconWrapper InformaBar-IconWrapper_closed"><svg viewBox="0 0 320 512" aria-hidden="true" focusable="false" role="img" xml:space="preserve" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" fill="currentColor" height="100%"><path fill="#ffffff" d="M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z"></path></svg></span></div></div></div></div><div class="Navigation-SecondaryMenuWrapper"><div class="FullScreenBackground Navigation-SecondaryMenuBackground"></div><div class="Navigation-SecondaryMenu"><nav data-testid="SecondaryMenu" class="SecondaryMenu"><a class="SecondaryMenu-Link" target="_blank" href="https://informaconnect.com/bioprocess-international-events/?utm_source=bpi-publication&utm_medium=top-menu">BPI Events</a><a class="SecondaryMenu-Link" data-discover="true" href="/about">About</a><a class="SecondaryMenu-Link" target="_blank" href="https://magazine.bioprocessintl.com/?pk=WEBS23B">Subscribe</a><a class="SecondaryMenu-Link" data-discover="true" href="/contribute">Contribute</a></nav></div></div><div style="padding-top:0px"></div><div id="navigation-header" class="Navigation-NavBase"><div data-testid="navBase" class="NavBase"><div class="NavBase-Content"><div class="FullScreenBackground NavBase-SecondaryMenuBackground"></div><div class="NavBase-HeaderWrapper"><div class="NavBase-IconsWrapper"><button data-testid="navBase-megaMenuButton" class="NavBase-MegaMenuButton" aria-label="Open Mega menu"><span data-component="icon" data-name="Bars" class="NavBase-MegaMenuIcon NavBase-MegaMenuIcon_iconVariant_small NavBase-MegaMenuIcon_iconType_bars" style="mask-image:url(/build/_assets/Bars-F4G2A5NO.svg);-webkit-mask-image:url(/build/_assets/Bars-F4G2A5NO.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button><button data-testid="SearchButtonDesktop" class="NavBase-SearchButtonDesktop" aria-label="Open Search"><span data-component="icon" data-name="Search" class="NavBase-SearchIcon NavBase-SearchIcon_iconVariant_large NavBase-SearchIcon_iconType_search" style="mask-image:url(/build/_assets/Search-T2ANYVG5.svg);-webkit-mask-image:url(/build/_assets/Search-T2ANYVG5.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button><button data-testid="SearchButtonTablet" class="NavBase-SearchButtonTablet" aria-label="Open Search in MegaMenu"><span data-component="icon" data-name="Search" class="NavBase-SearchIcon NavBase-SearchIcon_iconVariant_small NavBase-SearchIcon_iconType_search" style="mask-image:url(/build/_assets/Search-T2ANYVG5.svg);-webkit-mask-image:url(/build/_assets/Search-T2ANYVG5.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button></div><div class="NavBase-LogoWrapper"><button data-testid="navBase-LogoMegaMenuButton" class="NavBase-LogoMegaMenuButton" aria-label="Open Mega menu"><span data-component="icon" data-name="Bars" class="NavBase-LogoMegaMenuIcon NavBase-LogoMegaMenuIcon_iconVariant_small NavBase-LogoMegaMenuIcon_iconType_bars" style="mask-image:url(/build/_assets/Bars-F4G2A5NO.svg);-webkit-mask-image:url(/build/_assets/Bars-F4G2A5NO.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button><a class="NavBase-Logo" data-discover="true" href="/"><img data-testid="logo-image" data-component="image" class="NavBase-LogoImage" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta6717ea597e88ac9/6540ff1e76ec82040a90a249/BPI_-_Logo.svg?width=476&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta6717ea597e88ac9/6540ff1e76ec82040a90a249/BPI_-_Logo.svg?width=476&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></a></div><div class="NavBase-RegisterWrapper"><div data-module="newsletter-signup-promo"><div class="NewsletterSignupPromo-Button NewsletterSignupPromo-Button_small NewsletterSignupButton"><a data-component="button" data-testid="headerSmallNewsletterButton" class="Button Button_size_small Button_variant_primaryFilled" href="https://magazine.bioprocessintl.com/?pk=WEBS23B" target="_blank" data-name="subscribe-nav" data-action-type="sign-up"><span data-component="icon" data-name="Email" class="Button-Icon Button-Icon_position_left" style="mask-image:url(/build/_assets/Email-47H7P533.svg);-webkit-mask-image:url(/build/_assets/Email-47H7P533.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span><span class="Button-ContentWrapper">Subscribe</span></a></div><div class="NewsletterSignupPromo-Button NewsletterSignupPromo-Button_medium NewsletterSignupButton"><div data-component="social-share" class="SocialShare SocialShare_variant_layout Layout-SocialShare"><a target="_blank" rel="noreferrer" aria-label="Linkedin" class="Layout-SocialLink" href="https://www.linkedin.com/company/bioprocess-international/"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_layout"><span data-component="icon" data-name="Linkedin" class="SocialShare-Icon SocialShare-Icon_variant_layout SocialShare-Icon_type_linkedin" style="mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);-webkit-mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Twitter" class="Layout-SocialLink" href="https://twitter.com/bioprocessintl"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_layout"><span data-component="icon" data-name="Twitter" class="SocialShare-Icon SocialShare-Icon_variant_layout SocialShare-Icon_type_twitter" style="mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);-webkit-mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Youtube" class="Layout-SocialLink" href="https://www.youtube.com/@bioprocessinternational2391"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_layout"><span data-component="icon" data-name="Youtube" class="SocialShare-Icon SocialShare-Icon_variant_layout SocialShare-Icon_type_youtube" style="mask-image:url(/build/_assets/Youtube-S4PSC4UA.svg);-webkit-mask-image:url(/build/_assets/Youtube-S4PSC4UA.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a></div><a data-component="button" data-testid="headerMediumNewsletterButton" class="Button Button_size_medium Button_variant_primaryFilled" href="https://magazine.bioprocessintl.com/?pk=WEBS23B" target="_blank" data-name="subscribe-nav" data-action-type="sign-up"><span data-component="icon" data-name="Email" class="Button-Icon Button-Icon_position_left" style="mask-image:url(/build/_assets/Email-47H7P533.svg);-webkit-mask-image:url(/build/_assets/Email-47H7P533.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span><span class="Button-ContentWrapper">Subscribe</span></a></div></div><button data-testid="RegisterSearchButton" class="NavBase-RegisterSearchButton" aria-label="Open Search in MegaMenu"><span data-component="icon" data-name="Search" class="NavBase-SearchIcon NavBase-SearchIcon_iconVariant_large NavBase-SearchIcon_iconType_search" style="mask-image:url(/build/_assets/Search-T2ANYVG5.svg);-webkit-mask-image:url(/build/_assets/Search-T2ANYVG5.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button></div></div><div class="NavBase-SearchWrapper"><div class="FullScreenBackground NavBase-SearchBackground"></div><button data-testid="SearchCloseButton" class="NavBase-SearchCloseButton" aria-label="Close Search"><span data-component="icon" data-name="Close" class="NavBase-SearchIcon NavBase-SearchIcon_iconVariant_medium NavBase-SearchIcon_iconType_close" style="mask-image:url(/build/_assets/Close-KKOYAUD6.svg);-webkit-mask-image:url(/build/_assets/Close-KKOYAUD6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button></div></div></div><div class="Navigation-MainMenu"><div data-testid="mainMenu"><div class="FullScreenBackground MainMenu-BackgroundSubmenu"></div><div class="FullScreenBackground MainMenu-BackgroundMenuItem"></div><div class="MainMenu-Content"><div class="MainMenu-MegaMenuButtonWrapper"><button data-testid="mainMenu-MegaMenuButton" aria-label="Open MegaMenu" class="MainMenu-MegaMenuButton"><span data-component="icon" data-name="Bars" class="MainMenu-MegaMenuIcon" style="mask-image:url(/build/_assets/Bars-F4G2A5NO.svg);-webkit-mask-image:url(/build/_assets/Bars-F4G2A5NO.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button></div><div class="MainMenu-ItemsWrapper" role="menu"><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of Upstream"><span class="MainMenu-MainTitle">Upstream<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/upstream-processing/bioreactors">Bioreactors</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/upstream-processing/biochemicals-raw-materials">Biochemicals/Raw Materials</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/upstream-processing/cell-culture-media">Cell Culture Media</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/upstream-processing/expression-platforms">Expression Platforms</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/upstream-processing/microbial-cell-culture">Microbial Cell Culture</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/upstream-processing/perfusion-cell-culture">Perfusion Cell Culture</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/upstream-processing">Upstream</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/upstream-processing"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/introducing-super-refined-poloxamer-188-optimized-for-mammalian-cell-culture-with-exceptional-batch-to-batch-consistency"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Croda Pharma Ask the Expert</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta52221f8f722fb60/672252552ae2d2c25bd0eacc/10-29-2024-Croda-ATE-Slide-1.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta52221f8f722fb60/672252552ae2d2c25bd0eacc/10-29-2024-Croda-ATE-Slide-1.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/introducing-super-refined-poloxamer-188-optimized-for-mammalian-cell-culture-with-exceptional-batch-to-batch-consistency">Introducing Super Refined™ Poloxamer 188: Optimized for Mammalian Cell Culture with Exceptional Batch-to-Batch Consistency</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/introducing-super-refined-poloxamer-188-optimized-for-mammalian-cell-culture-with-exceptional-batch-to-batch-consistency">Introducing Super Refined™ Poloxamer 188: Optimized for Mammalian Cell Culture with Exceptional Batch-to-Batch Consistency</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Oct 29, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>1 Hr View</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/building-reliability-into-scale-up-targeted-optimization-for-aav-production"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Sartorius</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltc2815fa9653283fb/66ec56123cc5b3b0a287d5df/CGT-Campaign-Key-Visual-Gene-B-0003477.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltc2815fa9653283fb/66ec56123cc5b3b0a287d5df/CGT-Campaign-Key-Visual-Gene-B-0003477.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/building-reliability-into-scale-up-targeted-optimization-for-aav-production">Building Reliability Into Scale-Up: Targeted Optimization for AAV Production</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/building-reliability-into-scale-up-targeted-optimization-for-aav-production">Building Reliability Into Scale-Up: Targeted Optimization for AAV Production</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Sep 17, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>40 Min View</span></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of Downstream"><span class="MainMenu-MainTitle">Downstream<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/downstream-processing/chromatography">Chromatography</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/downstream-processing/filtration">Filtration</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/downstream-processing/separation-purification">Separation/Purification</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/downstream-processing/viral-clearance">Viral Clearance</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/downstream-processing">Downstream</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/downstream-processing"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Bio-Rad Ask the Expert webcast</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb698dd10ce0fff78/673783e6bdac76bd103e868b/slide1.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb698dd10ce0fff78/673783e6bdac76bd103e868b/slide1.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges">Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges">Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 14, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>15 Min View</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/aae-ms-a-powerful-method-to-assess-host-cell-protein-elisa-fit-for-purpose"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Cygnus AAE-MS</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt605950e2c84dbc27/673515e0f6be965b10392c86/AAE-MS_ad_image_1280x720.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt605950e2c84dbc27/673515e0f6be965b10392c86/AAE-MS_ad_image_1280x720.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/aae-ms-a-powerful-method-to-assess-host-cell-protein-elisa-fit-for-purpose">AAE-MS™: A Powerful Method to Assess Host Cell Protein ELISA Fit for Purpose</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/aae-ms-a-powerful-method-to-assess-host-cell-protein-elisa-fit-for-purpose">AAE-MS™: A Powerful Method to Assess Host Cell Protein ELISA Fit for Purpose</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 13, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>35 Min View</span></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of Manufacturing"><span class="MainMenu-MainTitle">Manufacturing<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/biosimilars">Biosimilars</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/continuous-bioprocessing">Continuous Bioprocessing</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/facility-design-engineering">Facility Design/Engineering</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/formulation">Formulation</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/single-use">Single Use</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/fill-finish">Fill/Finish</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/information-technology">Information Technology</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/process-monitoring-and-controls">Process Monitoring and Controls</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/supply-chain">Supply Chain</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/validation">Validation</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/manufacturing/cmc-forums">CMC Forums</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/manufacturing">Manufacturing</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/manufacturing"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">908 Devices Ask the Expert</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3ebae85a29c14385/673e45cd6fac62187a4d0ec3/11-19-2024-908-ATE-Site-Image.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3ebae85a29c14385/673e45cd6fac62187a4d0ec3/11-19-2024-908-ATE-Site-Image.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality">Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality">Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 19, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>30 Min View</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/introduction-to-lonza-cho-media-portfolio-harnessing-simplicity-with-the-therapro-cho-media-system"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Lonza Ask the Expert </span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt878d3807a987740f/6723e4f8ea57a35ffa463d42/10-31-2024-Lonza-ATE-Site.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt878d3807a987740f/6723e4f8ea57a35ffa463d42/10-31-2024-Lonza-ATE-Site.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/introduction-to-lonza-cho-media-portfolio-harnessing-simplicity-with-the-therapro-cho-media-system">Introduction to Lonza CHO Media Portfolio: Harnessing Simplicity with the TheraPRO® CHO Media System</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/introduction-to-lonza-cho-media-portfolio-harnessing-simplicity-with-the-therapro-cho-media-system">Introduction to Lonza CHO Media Portfolio: Harnessing Simplicity with the TheraPRO® CHO Media System</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Oct 31, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>50 Min View</span></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of Analytical"><span class="MainMenu-MainTitle">Analytical<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/qa-qc">QA/QC</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/cell-line-development">Cell Line Development</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/pat">PAT</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/product-characterization">Product Characterization</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/bioanalytical-methods">Bioanalytical Methods</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/process-development">Process Development</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/assays">Assays</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/analytical/laboratory-equipment">Laboratory Equipment</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/analytical">Analytical</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/analytical"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/out-of-the-box-computer-software-assurance-with-valgenesis-vlms"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">ValGenesis Ask the Expert webinar</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt7b0c2947a2efe76d/672d2be95b6a903e77a85126/11-07-2024-ValGenesis-ATE-Slide1.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt7b0c2947a2efe76d/672d2be95b6a903e77a85126/11-07-2024-ValGenesis-ATE-Slide1.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/out-of-the-box-computer-software-assurance-with-valgenesis-vlms">Out of the Box Computer Software Assurance with ValGenesis VLMS</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/out-of-the-box-computer-software-assurance-with-valgenesis-vlms">Out of the Box Computer Software Assurance with ValGenesis VLMS</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 7, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>30 Min View</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/innovative-approaches-to-enhance-cell-culture-density-for-high-quality-production"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Samsung S-Tesify</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt75859230194dee02/66ec682af99b3a803310a90f/S-testify_.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt75859230194dee02/66ec682af99b3a803310a90f/S-testify_.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/innovative-approaches-to-enhance-cell-culture-density-for-high-quality-production">Innovative Approaches to Enhance Cell Culture Density for High-Quality Production</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/innovative-approaches-to-enhance-cell-culture-density-for-high-quality-production">Innovative Approaches to Enhance Cell Culture Density for High-Quality Production</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Sep 19, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>15 Min View</span></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of Business"><span class="MainMenu-MainTitle">Business<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/bioregions">Bioregions</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/careers-training">Careers & Training</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/contract-services">Contract Services</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/economics">Economics</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/pre-clinical-and-clinical-trials">Pre-Clinical & Clinical Trials</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/risk-management">Risk Management</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/intellectual-property">Intellectual Property</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/business/regulatory-affairs">Regulatory Affairs</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/business">Business</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/business"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Lonza Ask the Expert webcast</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltcc8e38b7538dbf25/6740f228fbc6d82586601064/11-21-2024-Lonza-ATE-slide1.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltcc8e38b7538dbf25/6740f228fbc6d82586601064/11-21-2024-Lonza-ATE-slide1.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality">Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality">Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 21, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>30 Min View</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/bioprocess-insider/key-strategies-for-effective-technology-evaluation"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">thumbnail</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt20f52ba8f95fc0cb/66b50b3ce4286a875cff8015/AdobeStock_708481111.jpeg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt20f52ba8f95fc0cb/66b50b3ce4286a875cff8015/AdobeStock_708481111.jpeg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><a data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_bioprocessInsider ContentPreview-Category" data-discover="true" href="/bioprocess-insider">Bioprocess Insider</a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/bioprocess-insider/key-strategies-for-effective-technology-evaluation">Key strategies for effective technology evaluation</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/bioprocess-insider/key-strategies-for-effective-technology-evaluation">Key strategies for effective technology evaluation</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/kim-bennett">Kim Bennett</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Aug 8, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>2 Min Read</span></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of Therapeutic Modalities"><span class="MainMenu-MainTitle">Therapeutic Modalities<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/cell-therapies">Cell Therapies</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/emerging-therapeutics-manufacturing">Emerging Therapeutics</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/gene-therapies">Gene Therapies</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/large-molecule-development">Large Molecule Development</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/monoclonal-antibodies">MAb</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/personalized-medicine">Personalized Medicine</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/therapeutic-modalities/vaccines">Vaccines</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/therapeutic-modalities">Therapeutic Modalities</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/therapeutic-modalities"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/sponsored-content/decoding-aav-manufacturing-navigating-critical-quality-attributes-and-their-analytics"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">Roche ATE webinar</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb399cef493535335/6709708e7bf3c7af797141d0/10-10-2024-Roche-ATE-Site-Image.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb399cef493535335/6709708e7bf3c7af797141d0/10-10-2024-Roche-ATE-Site-Image.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><span data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_sponsoredContent Keyword_disabled ContentPreview-Category ContentPreview-Category_isSponsoredContent">Sponsored Content</span><a class="ContentPreview-IconWrapper" title="Link to all webinar" data-testid="content-preview-icon-link" data-discover="true" href="/webinars"><span data-component="icon" data-name="ChalkBoard" class="ContentPreview-Icon" style="mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);-webkit-mask-image:url(/build/_assets/ChalkBoard-7VYJPH3F.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/sponsored-content/decoding-aav-manufacturing-navigating-critical-quality-attributes-and-their-analytics">Decoding AAV Manufacturing: Navigating Critical Quality Attributes and their Analytics</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/sponsored-content/decoding-aav-manufacturing-navigating-critical-quality-attributes-and-their-analytics">Decoding AAV Manufacturing: Navigating Critical Quality Attributes and their Analytics</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/bpi-contributor">BPI Contributor</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Oct 11, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>20 Min View</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/bioprocess-insider/biomanufacturing-in-space-accelerating-therapy-development-on-earth"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">thumbnail</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt4464ea4100e2a8de/66a1392f540b829bcab36cd2/AdobeStock_320918695.jpeg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt4464ea4100e2a8de/66a1392f540b829bcab36cd2/AdobeStock_320918695.jpeg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><a data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_bioprocessInsider ContentPreview-Category" data-discover="true" href="/bioprocess-insider">Bioprocess Insider</a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/bioprocess-insider/biomanufacturing-in-space-accelerating-therapy-development-on-earth">Biomanufacturing in space accelerating therapy development on Earth</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/bioprocess-insider/biomanufacturing-in-space-accelerating-therapy-development-on-earth">Biomanufacturing in space accelerating therapy development on Earth</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/josh-abbott">Josh Abbott</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Jul 24, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>3 Min Read</span></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-MenuItemWrapper"><div class="MainMenu-MenuItem" role="menuitem" tabindex="0" data-testid="openSubMenu" aria-label="Open Sub menu of BioProcess Insider"><span class="MainMenu-MainTitle">BioProcess Insider<span data-component="icon" data-name="ChevronDown" class="MainMenu-SubMenuIcon" style="mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);-webkit-mask-image:url(/build/_assets/ChevronDown-PF4EH6J6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></div><div class="MainMenu-SubMenuWrapper"><div class="MainMenu-SubMenuContent"><div data-module="sub-menu" class="SubMenu MainMenu-SubMenu" role="presentation"><div class="SubMenu-Container"><div class="SubMenu-RelatedTopicsWrapper"><h4 class="SubMenu-RelatedTopics">Related Topics</h4><div class="SubMenu-CasualLinkWrapper" data-testid="related"><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/deal-making">Deal-Making</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/facilities-capacity">Facilities & Capacity</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/global-markets">Global Markets</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/regulations">Regulations</a></li></ul><ul class="SubMenu-CasualLinkList"><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/therapeutic-class">Therapeutic Class</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/upstream-downstream-processing">Upstream & Downstream Processing</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/webcasts">Webcasts</a></li><li class="SubMenu-CasualLinkItem"><a class="SubMenu-ItemLink" data-testid="sub-menu-item-link" data-discover="true" href="/bioprocess-insider/bpi-podcasts">BioProcess Insider Podcasts</a></li></ul></div></div><div class="SubMenu-RecentContentWrapper" data-testid="recent"><div class="SubMenu-RecentContentHeading"><h4 data-testid="recent-title" class="SubMenu-RecentText">Recent in <a class="SubMenu-RecentTopicTerm" data-discover="true" href="/bioprocess-insider">BioProcess Insider</a></h4><div data-testid="see-more" class="SubMenu-SeeMore"><a class="SubMenu-MoreContent" data-discover="true" href="/bioprocess-insider"><span class="SubMenu-SeeMoreText">See all</span><span data-component="icon" data-name="ChevronRight" class="SubMenu-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div><div class="SubMenu-ContentWrapper"><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/deal-making/halozyme-eyes-continuous-manufacturing-platform-in-2-1bn-evotec-bid"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">thumbnail</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3cc2b4da01031668/6740715c0ab0261fd1630099/m_and_a_timbrk.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3cc2b4da01031668/6740715c0ab0261fd1630099/m_and_a_timbrk.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><a data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_dealMaking ContentPreview-Category" data-discover="true" href="/bioprocess-insider/deal-making">Deal-Making</a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/deal-making/halozyme-eyes-continuous-manufacturing-platform-in-2-1bn-evotec-bid">Halozyme’s $2.1bn Evotec bid: First the ins, now the out</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/deal-making/halozyme-eyes-continuous-manufacturing-platform-in-2-1bn-evotec-bid">Halozyme’s $2.1bn Evotec bid: First the ins, now the out</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/dan-stanton">Dan Stanton</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 25, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>3 Min Read</span></div></div></div></div></div></div><div class="ContentPreview" data-module="content-preview" data-variant="card-vertical"><div class="ContentPreview-Wrapper ContentPreview-Wrapper_variant_cardVertical"><a data-testid="thumbnail" data-discover="true" href="/deal-making/cdmo-success-stories-news-from-lonza-samsung-bio-fujifilm"><div class="ContentPreview-ImageContainer"><span data-testid="content-preview-screen-reader-text" class="ContentPreview-ImageScreenReaderText">thumbnail</span><img data-testid="content-preview-image" data-component="image" class="ContentPreview-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt67fc0d78c80e874f/673f28ede1e4f3389fa4a35e/manufacturing_deal_Wavebreakmedia.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt67fc0d78c80e874f/673f28ede1e4f3389fa4a35e/manufacturing_deal_Wavebreakmedia.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></div></a><a data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_dealMaking ContentPreview-Category" data-discover="true" href="/bioprocess-insider/deal-making">Deal-Making</a><div class="VerticalCard"><div class="VerticalCard-Body"><a class="VerticalCard-Title VerticalCard-Title_displayOption_default" data-testid="preview-default-title" data-discover="true" href="/deal-making/cdmo-success-stories-news-from-lonza-samsung-bio-fujifilm">CDMO success stories: News from Lonza, Samsung Bio, Fujifilm</a><a class="VerticalCard-Title VerticalCard-Title_displayOption_mobile" data-testid="preview-mobile-title" data-discover="true" href="/deal-making/cdmo-success-stories-news-from-lonza-samsung-bio-fujifilm">CDMO success stories: News from Lonza, Samsung Bio, Fujifilm</a><div class="Contributors Contributors_variant_slimline VerticalCard-ContributorsWrapper" data-component="contributors"><div class="Contributors-InfoWrapper"><span class="Contributors-ByText" data-testid="by-text">by</span><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/dan-stanton">Dan Stanton</a></div></div></div><div class="VerticalCard-Footer"><span class="VerticalCard-Date" data-testid="vertical-card-date">Nov 21, 2024</span><div data-module="card-time" class="CardTime"><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>3 Min Read</span></div></div></div></div></div></div></div></div></div></div></div></div></div></div><div class="MainMenu-SearchButtonWrapper"><button data-testid="mainMenu-SearchButton" aria-label="Open Search" class="MainMenu-SearchButton"><span data-component="icon" data-name="Search" class="MainMenu-SearchButtonIcon" style="mask-image:url(/build/_assets/Search-T2ANYVG5.svg);-webkit-mask-image:url(/build/_assets/Search-T2ANYVG5.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button></div></div><div class="MainMenu-SearchWrapper"><div class="FullScreenBackground MainMenu-SearchBackground MainMenu-SearchBackground_withSearchBar"></div><button data-testid="mainMenu-SearchCloseButton" class="MainMenu-SearchCloseButton" aria-label="Close Search"><span data-component="icon" data-name="Close" class="MainMenu-SearchCloseIcon" style="mask-image:url(/build/_assets/Close-KKOYAUD6.svg);-webkit-mask-image:url(/build/_assets/Close-KKOYAUD6.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></button></div></div></div></div></nav><section class="Layout-Section"><div id="iiris-identity" data-testid="iris-identity" configid="a4a245652cad256461fe5c2eeb8ad5e0"></div><div data-template="article"><div class="TwoColumnLayout"><div id="portal-root"></div><div class="TwoColumnLayout-Head"><div class="ArticleBase-Header"><ul class="ArticleBase-Topics" data-testid="article-topics"><li class="ArticleBase-Topic"><a data-component="keyword" class="Keyword Keyword_variant_category Keyword_title_bpiPodcasts" data-discover="true" href="/bioprocess-insider/bpi-podcasts">BPI Podcasts</a></li><li class="ArticleBase-Topic"><a data-component="keyword" class="Keyword Keyword_variant_category Keyword_title_bioprocessInsider" data-discover="true" href="/bioprocess-insider">Bioprocess Insider</a></li><li class="ArticleBase-Topic"><a data-component="keyword" class="Keyword Keyword_variant_category Keyword_title_upstreamDownstreamProcessing" data-discover="true" href="/bioprocess-insider/upstream-downstream-processing">Upstream & Downstream Processing</a></li></ul><a class="ArticleBase-Header" data-testid="article-base-header"><a data-discover="true" href="/program/bioprocess-insider"><div data-component="program-header" class="ProgramHeader ProgramHeader_mode_logo"><div data-testid="program-header-content" class="ProgramHeader-Content ProgramHeader-Content_mode_logo" style="background-color:#undefined"><img data-component="image" class="ProgramHeader-Logo ProgramHeader-Logo_mode_logo" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blte7957c3a38c95fac/65c500a3a2f62c040a2fed1f/Insider-Header-2019-700w.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blte7957c3a38c95fac/65c500a3a2f62c040a2fed1f/Insider-Header-2019-700w.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="BioProcess Insider" title="BioProcess Insider"/><div class="ProgramHeader-Description ProgramHeader-Description_mode_logo" data-testid="program-header-description"></div></div><div class=""></div></div></a></a><div><h1 class="ArticleBase-HeaderTitle"><noscript><span class="ArticleBase-LargeTitle">Podcast: Lumen using spirulina to make ‘edible’ antibody drugs</span></noscript><span class="ArticleBase-DefaultTitle" data-testid="article-default-title">Podcast: Lumen using spirulina to make ‘edible’ antibody drugs</span></h1></div></div></div><div class="TwoColumnLayout-Content"><div class="TwoColumnLayout-Body"><div class="ArticleBase-Body" data-testid="article-base-body"><div class="ArticleBase-Contributors" data-testid="article-base-contributors"><div class="Contributors Contributors_variant_normal Contributors_hasAvatar" data-component="contributors"><div class="Contributors-AvatarWrapper"><a class="Contributors-AvatarLink" aria-label="Dan Stanton" data-discover="true" href="/author/dan-stanton"><img aria-hidden="true" data-testid="contributor-avatar" data-component="image" class="Contributors-Avatar" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg?width=100&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg?width=100&auto=webp&quality=80&disable=upscale" loading="lazy" alt="Picture of Dan Stanton" title="Picture of Dan Stanton"/></a></div><div class="Contributors-InfoWrapper"><a class="Contributors-ContributorName" data-testid="contributor-name" data-discover="true" href="/author/dan-stanton">Dan Stanton</a><span class="Contributors-ContributorTitle" data-testid="contributor-title">, Editorial director</span><p class="Contributors-Date" data-testid="contributors-date">July 25, 2022</p></div></div></div><div class="ArticlePodcast-Media"><div data-component="media"><div class="Media Media_audio"><iframe loading="lazy" width="100%" height="150" style="border: none; min-width: min(100%, 430px);" title="Snippets from BIO: Lumen CEO talks edible antibodies" allowtransparency="true" scrolling="no" data-name="pb-iframe-player" src="https://www.podbean.com/player-v2/?i=q46c6-127b7c4-pb&from=pb6admin&share=1&download=1&rtl=0&fonts=Arial&skin=1&font-color=auto&logo_link=episode_page&btn-skin=7"></iframe></div></div></div><div class="SocialShare"><div data-component="social-share" class="SocialShare SocialShare_variant_button ArticleBase-SocialShare ArticleBase-SocialShare_first"><a target="_blank" rel="noreferrer" aria-label="Linkedin" href="https://www.linkedin.com/sharing/share-offsite/?url=https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_button"><span data-component="icon" data-name="Linkedin" class="SocialShare-Icon SocialShare-Icon_variant_button SocialShare-Icon_type_linkedin" style="mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);-webkit-mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Twitter" href="http://www.twitter.com/intent/tweet?url=https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_button"><span data-component="icon" data-name="Twitter" class="SocialShare-Icon SocialShare-Icon_variant_button SocialShare-Icon_type_twitter" style="mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);-webkit-mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Email" href="/cdn-cgi/l/email-protection#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"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_button"><span data-component="icon" data-name="Email" class="SocialShare-Icon SocialShare-Icon_variant_button SocialShare-Icon_type_email" style="mask-image:url(/build/_assets/Email-47H7P533.svg);-webkit-mask-image:url(/build/_assets/Email-47H7P533.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a></div></div><div class="ArticleBase-BodyContent ArticleBase-BodyContent_Podcast" data-testid="article-base-body-content"><div data-module="content" class="ContentModule-Wrapper"><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text"><span class="ContentText-BodyTextChunk ContentText-BodyTextChunk_bold">We sit down with Lumen Biosciences CEO Brian Finrow to discuss how his company hopes to use its spirulina-based platform to develop drugs targeting gastrointestinal disorders.</span></span></p><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">Lumen Biosciences is a biotech looking to unlock the full potential of biologic drugs, whose promise has been held back by the lack of scalable technology.</span></p><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">The firm is developing ‘oral antibodies’ using its platform based on spirulina– the protein-rich cyanobacteria touted by many health enthusiasts as a ‘superfood’ – to create tiny factories that churn out therapeutic antibodies.</span></p><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><img data-component="image" class="ContentParagraph-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3ffbd080cf28499f/658d74c5f5ee23040a1a8568/spirulina--300x241.jpg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3ffbd080cf28499f/658d74c5f5ee23040a1a8568/spirulina--300x241.jpg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="spirulina--300x241.jpg" title="spirulina--300x241.jpg"/></p><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">Image: Stock Photo Secrets</span></p><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">More details can be found in the text box below, but as part of the BioProcess International Theater at BIO in San Diego last month, I spoke with CEO and co-founder Brian Finrow.</span></p><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">Listen to the full interview as part of the Bioprocess Insider Expression Platform podcast here, on </span><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text"><a class="ContentText-BodyTextChunk ContentText-BodyTextChunk_link" rel="noopener" target="_blank" href="https://podcasts.apple.com/fr/podcast/the-bioprocess-insider-expression-platform/id1549869188">Apple</a></span><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">, </span><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text"><a class="ContentText-BodyTextChunk ContentText-BodyTextChunk_link" rel="noopener" target="_blank" href="https://music.amazon.com/podcasts/f5eaf75c-1b97-41e0-ba63-3c31ef68ebeb/the-bioprocess-insider-expression-platform">Amazon</a></span><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">, </span><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text"><a class="ContentText-BodyTextChunk ContentText-BodyTextChunk_link" rel="noopener" target="_blank" href="https://open.spotify.com/show/0Sh7c6SJOJ7nsFLNPuW7B0">Spotify</a></span><span class="ContentText ContentText_variant_bodyNormal" data-testid="content-text">, or wherever you get your podcasts.</span></p><div><div class="Table-ScrollableWrapper"><table data-component="table" class="Table ContentTable" style="margin-top:-30px"><thead class="Table-Head"><tr class="Table-Row"></tr></thead><tbody class="Table-Body"></tbody></table></div></div></div></div><div class="SocialShare"><div data-component="social-share" class="SocialShare SocialShare_variant_button ArticleBase-SocialShare ArticleBase-SocialShare_second"><a target="_blank" rel="noreferrer" aria-label="Linkedin" href="https://www.linkedin.com/sharing/share-offsite/?url=https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_button"><span data-component="icon" data-name="Linkedin" class="SocialShare-Icon SocialShare-Icon_variant_button SocialShare-Icon_type_linkedin" style="mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);-webkit-mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Twitter" href="http://www.twitter.com/intent/tweet?url=https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_button"><span data-component="icon" data-name="Twitter" class="SocialShare-Icon SocialShare-Icon_variant_button SocialShare-Icon_type_twitter" style="mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);-webkit-mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Email" href="/cdn-cgi/l/email-protection#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"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_button"><span data-component="icon" data-name="Email" class="SocialShare-Icon SocialShare-Icon_variant_button SocialShare-Icon_type_email" style="mask-image:url(/build/_assets/Email-47H7P533.svg);-webkit-mask-image:url(/build/_assets/Email-47H7P533.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a></div></div><div class="ArticleBase-ContributorsWrapper"><h2 class="ArticleBase-ContributorsTitle">About the Author</h2><div class="ArticleBase-ContributorsSummary"><div data-component="contributor-summary" class="ContributorSummary ContributorSummary_variant_author"><div class="ContributorSummary-ImageWrapper ContributorSummary-ImageWrapper_variant_author"><a data-testid="contributor-summary-img-link" data-discover="true" href="/author/dan-stanton"><img data-component="image" class="ContributorSummary-Image ContributorSummary-Image_variant_author" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg?width=400&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg?width=400&auto=webp&quality=80&disable=upscale" loading="lazy" alt="Dan Stanton" title="Dan Stanton"/></a></div><div class="ContributorSummary-InfoWrapper ContributorSummary-InfoWrapper_variant_author"><div class="ContributorSummary-TitleWrapper"><a data-testid="contributor-summary-title-link" data-discover="true" href="/author/dan-stanton"><p class="ContributorSummary-Title ContributorSummary-Title_variant_author" data-testid="contributor-summary-title">Dan Stanton</p></a></div><div class="ContributorSummary-SubTitleWrapper ContributorSummary-SubTitleWrapper_variant_author"><p class="ContributorSummary-SubTitle ContributorSummary-SubTitle_variant_author" data-testid="contributor-summary-subtitle">Editorial director</p></div><div class="ContributorSummary-ContentWrapper ContributorSummary-ContentWrapper_variant_author"><div class="ContributorSummary-Content ContributorSummary-Content_variant_author" data-testid="contributor-summary-content"><p class="ContentParagraph ContentParagraph_align_left" data-testid="content-paragraph"><span class="ContentText ContentText_variant_bodyNoneStyle" data-testid="content-text">Journalist covering the international biopharmaceutical manufacturing and processing industries.</span><br/><span class="ContentText ContentText_variant_bodyNoneStyle" data-testid="content-text">Founder and editor of Bioprocess Insider, a daily news offshoot of publication Bioprocess International, with expertise in the pharmaceutical and healthcare sectors, in particular, the following niches: CROs, CDMOs, M&A, IPOs, biotech, bioprocessing methods and equipment, drug delivery, regulatory affairs and business development.</span><br/><br/><span class="ContentText ContentText_variant_bodyNoneStyle" data-testid="content-text">From London, UK originally but currently based in Montpellier, France through a round-a-bout adventure that has seen me live and work in Leeds (UK), London, New Zealand, and China.</span></p></div></div></div><div class="ContributorSummary-SeeMore"><a data-component="button" class="Button Button_size_medium Button_variant_textLink" rel="" data-discover="true" href="/author/dan-stanton"><span class="Button-ContentWrapper"><span class="ContributorSummary-SeeMoreText"><span>See more from Dan Stanton</span><span data-component="icon" data-name="ChevronRight" class="ContributorSummary-SeeMoreIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></span></a></div></div></div></div><p class="IirisRecommendation-Title">You May Also Like</p><hr class="IirisRecommendation-TitleHr"/><div bordercolor="#e6e6e6" borderRadius="5" brandName="bioprocessintl" brand_family="lifesciences" cardwidth="210px" class="iris-recommend iris-recommend-non-sticky" columns="2" data-component="iris-recommendation" dateformat="DD/MM/YYYY" datetimebgcolor="#ffffff" datetimefontcolor="#767676" datetimefontsize="12" division="ic" dropShadow="#FFEB00" entity="content" entitytagbackground="#333333BF" entitytagbordercolor="#333333" entitytagfont="#ffffff" id="widget-1708438882494" imageHeight="182" imagePosition="vertical" imageWidth="324" recipe="related-items" redirectmode="same" rows="2" showborder="yes" showby="" showdate="yes" showentitytag="yes" showtime="" title="" widgetType="grid" brand="bioprocessintl" itemUrl="" style="max-width:1100px"></div><div><div class="ArticleBase-AdSponsored"></div></div></div></div><div class="TwoColumnLayout-Sidebar"><div class="Sidebar" data-module="sidebar"><div class="Sidebar-SidebarItem" data-testid="sidebar-item"><div data-module="content-cards" class="ContentCards ContentCards_sidebar"><div class="ContentCards-CardsWrapper ContentCards-CardsWrapper_default"><div class="ContentCards-Header ContentCards-Header_default" data-testid="content-cards-header"><h3 class="ContentCards-Title" data-testid="contentCardsTitle">Webinars</h3></div><div class="ContentCards-Content ContentCards-Content_default"><div class="ContentCards-ContentPreview ContentCards-ContentPreview_default" data-testid="content-preview-default"><div class="ContentPreview" data-module="content-preview" data-variant="card-horizontal"><div class="HorizontalCard"><div class="HorizontalCard-ImageWrapper"><a target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges"><span class="HorizontalCard-ImageScreenReaderText">Ask the Expert webcasts</span><img data-component="image" class="HorizontalCard-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png?width=300&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png?width=300&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></a><a class="HorizontalCard-IconWrapper" title="Link to all externallink" target="_blank" rel="nofollow" data-testid="content-preview-icon-link" href="https://bpi.bioprocessintl.com/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges"><span data-component="icon" data-name="ExternalLink" class="HorizontalCard-Icon" style="mask-image:url(/build/_assets/ExternalLink-W6ZQAM2T.svg);-webkit-mask-image:url(/build/_assets/ExternalLink-W6ZQAM2T.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div><div class="HorizontalCard-ContentWrapper"><div class="HorizontalCard-KeywordWrapper"><a data-component="keyword" class="Keyword Keyword_variant_alternate Keyword_title_ateWebcasts HorizontalCard-Keyword" data-discover="true" href="/ate-webcasts">ATE Webcasts</a></div><div class="HorizontalCard-TitleWrapper"><a class="HorizontalCard-Title" data-testid="preview-default-title" target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges">Register Now: Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges</a></div><div class="HorizontalCard-MobileTitleWrapper"><a class="HorizontalCard-Title" data-testid="preview-mobile-title" target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges">Register Now: Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges</a></div></div></div></div></div><div class="ContentCards-ContentPreview ContentCards-ContentPreview_default" data-testid="content-preview-default"><div class="ContentPreview" data-module="content-preview" data-variant="card-horizontal"><div class="HorizontalCard"><div class="HorizontalCard-ImageWrapper"><a target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality"><span class="HorizontalCard-ImageScreenReaderText">Ask the Expert webcasts</span><img data-component="image" class="HorizontalCard-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png?width=300&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png?width=300&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></a><a class="HorizontalCard-IconWrapper" title="Link to all externallink" target="_blank" rel="nofollow" data-testid="content-preview-icon-link" href="https://bpi.bioprocessintl.com/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality"><span data-component="icon" data-name="ExternalLink" class="HorizontalCard-Icon" style="mask-image:url(/build/_assets/ExternalLink-W6ZQAM2T.svg);-webkit-mask-image:url(/build/_assets/ExternalLink-W6ZQAM2T.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div><div class="HorizontalCard-ContentWrapper"><div class="HorizontalCard-KeywordWrapper"><a data-component="keyword" class="Keyword Keyword_variant_alternate Keyword_title_ateWebcasts HorizontalCard-Keyword" data-discover="true" href="/ate-webcasts">ATE Webcasts</a></div><div class="HorizontalCard-TitleWrapper"><a class="HorizontalCard-Title" data-testid="preview-default-title" target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality">Register Now: Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality</a></div><div class="HorizontalCard-MobileTitleWrapper"><a class="HorizontalCard-Title" data-testid="preview-mobile-title" target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality">Register Now: Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality</a></div></div></div></div></div><div class="ContentCards-ContentPreview ContentCards-ContentPreview_default" data-testid="content-preview-default"><div class="ContentPreview" data-module="content-preview" data-variant="card-horizontal"><div class="HorizontalCard"><div class="HorizontalCard-ImageWrapper"><a target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality?utm_source=bpi&utm_medium=social&utm_campaign=ATE-webcasts"><span class="HorizontalCard-ImageScreenReaderText">Ask the Expert webcasts</span><img data-component="image" class="HorizontalCard-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png?width=300&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png?width=300&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></a><a class="HorizontalCard-IconWrapper" title="Link to all externallink" target="_blank" rel="nofollow" data-testid="content-preview-icon-link" href="https://bpi.bioprocessintl.com/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality?utm_source=bpi&utm_medium=social&utm_campaign=ATE-webcasts"><span data-component="icon" data-name="ExternalLink" class="HorizontalCard-Icon" style="mask-image:url(/build/_assets/ExternalLink-W6ZQAM2T.svg);-webkit-mask-image:url(/build/_assets/ExternalLink-W6ZQAM2T.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div><div class="HorizontalCard-ContentWrapper"><div class="HorizontalCard-KeywordWrapper"><a data-component="keyword" class="Keyword Keyword_variant_alternate Keyword_title_ateWebcasts HorizontalCard-Keyword" data-discover="true" href="/ate-webcasts">ATE Webcasts</a></div><div class="HorizontalCard-TitleWrapper"><a class="HorizontalCard-Title" data-testid="preview-default-title" target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality?utm_source=bpi&utm_medium=social&utm_campaign=ATE-webcasts">Register Now: Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality</a></div><div class="HorizontalCard-MobileTitleWrapper"><a class="HorizontalCard-Title" data-testid="preview-mobile-title" target="_blank" rel="nofollow" href="https://bpi.bioprocessintl.com/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality?utm_source=bpi&utm_medium=social&utm_campaign=ATE-webcasts">Register Now: Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality</a></div></div></div></div></div></div></div></div></div><div class="Sidebar-SidebarItem" data-testid="sidebar-item"><div data-component="content-list" class="ContentList"><div class="ContentList-Header"><span data-component="icon" data-name="Checkmark" class="ContentList-Icon" style="mask-image:url(/build/_assets/Checkmark-7MGBARCD.svg);-webkit-mask-image:url(/build/_assets/Checkmark-7MGBARCD.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span><span class="ContentList-Title" data-testid="content-list-title">Latest Content</span></div><ul class="ContentList-List"><li class="ContentList-ListItem"><a data-testid="content-list-item-title" data-discover="true" href="/regulations/vaccine-makers-sanguine-amid-threat-from-us-health-nominees-rfk-jr-and-dr-oz" target=""><p class="ContentList-ListItemTitle">Vaccine makers sanguine amid threat from US health nominees RFK Jr. and Dr. Oz</p></a><span class="ContentList-ListItemDate" data-testid="content-list-item-date">Nov 27, 2024<div data-module="card-time" class="CardTime"><span class="CardTime-SeparatorLine">|</span><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>5 Min Read</span></div></div></span></li><li class="ContentList-ListItem"><a data-testid="content-list-item-title" data-discover="true" href="/global-markets/social-media-murmurs-industry-contemplates-supply-chain-post-biosecure" target=""><p class="ContentList-ListItemTitle">Social media murmurs: Industry contemplates supply chain post-BIOSECURE</p></a><span class="ContentList-ListItemDate" data-testid="content-list-item-date">Nov 27, 2024<div data-module="card-time" class="CardTime"><span class="CardTime-SeparatorLine">|</span><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>3 Min Read</span></div></div></span></li><li class="ContentList-ListItem"><a data-testid="content-list-item-title" data-discover="true" href="/sponsored-content/driving-innovation-in-drug-development-and-production" target=""><p class="ContentList-ListItemTitle">Driving Innovation in Drug Development and Production</p></a><span class="ContentList-ListItemDate" data-testid="content-list-item-date">Nov 26, 2024</span></li><li class="ContentList-ListItem"><a data-testid="content-list-item-title" data-discover="true" href="/facilities-capacity/chop-teams-with-inca-to-bring-car-t-therapies-to-children-in-brazil" target=""><p class="ContentList-ListItemTitle">CHOP teams with INCA to bring CAR-T therapies to children in Brazil</p></a><span class="ContentList-ListItemDate" data-testid="content-list-item-date">Nov 25, 2024<div data-module="card-time" class="CardTime"><span class="CardTime-SeparatorLine">|</span><div data-component="article-read-time" class="ArticleReadTime ArticleReadTime_size_small CardTime-ReadTime"><span>4 Min Read</span></div></div></span></li></ul></div></div><div class="Sidebar-SidebarItem" data-testid="sidebar-item"><div data-module="linked-image" class="LinkedImage LinkedImage_isLarge LinkedImage_moduleLocation_sidebar"><div class="LinkedImage-Header"><p class="LinkedImage-Title" data-testid="linked-image-title">Get the News</p><a class="LinkedImage-DefaultCtaWrapper" target="_blank" href="https://bpi.bioprocessintl.com/bioprocess-insider-subscription"><span class="LinkedImage-DefaultCtaButton">SUBSCRIBE</span><span data-component="icon" data-name="ChevronRight" class="LinkedImage-DefaultCtaIcon" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div><div class="LinkedImage-LogoListWrapper"><div class="LinkedImage-LogoList"><div class="LinkedImage-LogoWrapper"><a target="_blank" href="https://bpi.bioprocessintl.com/bioprocess-insider-subscription"><img data-component="image" class="LinkedImage-Logo" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt52ab5c92a7623abe/672a934f35a2cd6b857059f1/Insider-Subscribe-1280x720-fullv2.png?width=300&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt52ab5c92a7623abe/672a934f35a2cd6b857059f1/Insider-Subscribe-1280x720-fullv2.png?width=300&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></a></div></div></div><div class="LinkedImage-MobileCtaWrapper"><a data-component="button" data-testid="button_a" class="Button Button_size_medium Button_variant_textLink LinkedImage-MobileCtaButton" href="https://bpi.bioprocessintl.com/bioprocess-insider-subscription" target="_blank"><span class="Button-ContentWrapper">SUBSCRIBE</span><span data-component="icon" data-name="ChevronRight" class="Button-Icon Button-Icon_position_right" style="mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);-webkit-mask-image:url(/build/_assets/ChevronRight-NHDKEYGJ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div></div></div><div class="Sidebar-SidebarItem" data-testid="sidebar-item"><div data-module="content-spotlight" class="ContentSpotlight ContentSpotlight_mode_light"><article class="ContentSpotlight-Article ContentSpotlight-Article_isReversed ContentSpotlight-Article_isSidebar" moduleDesign="standard" text-alignment="center" data-testid="content-spotlight-article"><div class="ContentSpotlight-ImageContainer" data-testid="content-spotlight-image-container"><div class="ContentSpotlight-KeywordList"><div class="ContentSpotlight-KeywordWrapper"><a data-component="keyword" class="Keyword Keyword_variant_standard Keyword_title_bpiPodcasts ContentSpotlight-Keyword" data-discover="true" href="/bioprocess-insider/bpi-podcasts">BPI Podcasts</a></div></div><a data-discover="true" href="/bpi-podcasts/podcast-sustainability-is-about-health-equity-says-scaleready-and-germfree"><img data-component="image" class="ContentSpotlight-Image" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt6e2069d504af847e/66b1e8d09cb2930a4db78268/VOB_scale_ready.jpeg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt6e2069d504af847e/66b1e8d09cb2930a4db78268/VOB_scale_ready.jpeg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="" title=""/></a><a class="ContentSpotlight-IconWrapper" title="Link to all podcast" data-testid="content-spotlight-icon-link" data-discover="true" href="/podcasts"><span data-component="icon" data-name="Microphone" class="ContentSpotlight-Icon" style="mask-image:url(/build/_assets/Microphone-W4D26BPI.svg);-webkit-mask-image:url(/build/_assets/Microphone-W4D26BPI.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></a></div><div class="ContentSpotlight-ContentContainer ContentSpotlight-ContentContainer_textAlignment_center ContentSpotlight-ContentContainer_isSidebar" data-testid="content-spotlight-content-container"><p class="ContentSpotlight-ContentSummary" data-testid="content-spotlight-summary">Content Spotlight</p><a data-discover="true" href="/bpi-podcasts/podcast-sustainability-is-about-health-equity-says-scaleready-and-germfree"><h2 class="ContentSpotlight-ContentHeading" data-testid="content-spotlight-heading">Podcast: Sustainability is about health equity, says ScaleReady and Germfree</h2></a><div class="ContentSpotlight-ContentBodyWrapper ContentSpotlight-ContentBodyWrapper_isSidebar"><p class="ContentSpotlight-ContentBody" data-testid="content-spotlight-body">ScaleReady and Germfree discuss the need to rethink sustainability and move towards a more standardized and simplistic manufacturing model to ensure health equity can be achieved.</p></div><div class="ContentSpotlight-ButtonContainer"><a data-testid="content-spotlight-button-link" data-discover="true" href="/bpi-podcasts/podcast-sustainability-is-about-health-equity-says-scaleready-and-germfree"><button data-component="button" data-testid="button_button" class="Button Button_size_medium Button_variant_darkOutlined" type="button"><span class="Button-ContentWrapper">Listen Now</span></button></a></div></div></article></div></div></div></div></div></div></div></section><footer data-module="footer" class="Footer"><div class="Footer-Background"></div><div data-testid="logo" class="Footer-LogoContainer Footer-LogoContainer_length_3"><a data-discover="true" href="/"><img title="BioProcess International logo" data-component="image" class="Footer-LogoImage Footer-LogoImage_length_3" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta6717ea597e88ac9/6540ff1e76ec82040a90a249/BPI_-_Logo.svg?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta6717ea597e88ac9/6540ff1e76ec82040a90a249/BPI_-_Logo.svg?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="BioProcess International logo"/></a></div><div data-testid="LinkSection" class="LinkSection LinkSection_length_3"><h5 class="LinkSection-Title" data-testid="link-section-title">BPI Content</h5><div class="LinkSection-LinksWrapper"><a class="LinkSection-Link" data-discover="true" href="/publications" target="_self">BPI Archive</a><a class="LinkSection-Link" data-discover="true" href="/program/bioprocess-insider" target="_self">BioProcess Insider News</a><a class="LinkSection-Link" target="_blank" rel="noreferrer" href="https://bpi.bioprocessintl.com/bioprocess-insider-subscription">Subscribe to BioProcess Insider Newsletter</a></div></div><div data-testid="LinkSection" class="LinkSection LinkSection_length_3"><h5 class="LinkSection-Title" data-testid="link-section-title">Resources</h5><div class="LinkSection-LinksWrapper"><a class="LinkSection-Link" data-discover="true" href="/events" target="_self">Events</a><a class="LinkSection-Link" data-discover="true" href="/webinars" target="_self">Webinars</a><a class="LinkSection-Link" data-discover="true" href="/program/white-papers" target="_self">White Papers</a><a class="LinkSection-Link" data-discover="true" href="/program/poster-hall" target="_self">Posters</a><a class="LinkSection-Link" data-discover="true" href="/videos" target="_self">Videos</a><a class="LinkSection-Link" data-discover="true" href="/podcasts" target="_self">Podcasts</a></div></div><div data-testid="LinkSection" class="LinkSection LinkSection_length_3"><h5 class="LinkSection-Title" data-testid="link-section-title">About BPI</h5><div class="LinkSection-LinksWrapper"><a class="LinkSection-Link" data-discover="true" href="/about" target="_self">Who We Are</a><a class="LinkSection-Link" data-discover="true" href="/editorial-advisors" target="_self">Editorial Advisors</a><a class="LinkSection-Link" data-discover="true" href="/contribute" target="_self">Author Guidelines</a><a class="LinkSection-Link" target="_blank" rel="noreferrer" href="https://get.informaconnect.com/bpipublication/sponsorship/?utm_source=BioprocessIntl&utm_medium=web&utm_campaign=advertise">Advertising/Media Kit</a><a class="LinkSection-Link" rel="noreferrer" data-discover="true" href="/reprints-and-list-rental" target="_blank">List Rental/Reprints</a><a class="LinkSection-Link" target="_blank" rel="noreferrer" href="https://informaconnect.com/careers/">Careers</a></div></div><div data-testid="registration" class="Footer-RegistrationWrapper"><div class="RegistrationSection RegistrationSection_linkSectionLength_3"><h5 class="RegistrationSection-Title">Join Us</h5><div class="Layout-Register Layout-Register_variant_footer"></div><div class="Layout-NewsLetter Layout-NewsLetter_variant_footer"><div data-module="newsletter-signup-promo"><a data-component="button" data-testid="footerNewsletterButton" class="Button Button_size_medium Button_variant_primaryFilled" href="https://magazine.bioprocessintl.com/?pk=WEBS23B" target="_blank" data-name="subscribe-footer" data-action-type="sign-up"><span class="Button-ContentWrapper">Subscribe</span></a></div></div></div></div><div data-testid="social" class="SocialSection SocialSection_linkSectionLength_3"><h5 class="SocialSection-Title">Follow Us</h5><div data-component="social-share" class="SocialShare SocialShare_variant_layout"><a target="_blank" rel="noreferrer" aria-label="Linkedin" href="https://www.linkedin.com/company/bioprocess-international/"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_layout"><span data-component="icon" data-name="Linkedin" class="SocialShare-Icon SocialShare-Icon_variant_layout SocialShare-Icon_type_linkedin" style="mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);-webkit-mask-image:url(/build/_assets/Linkedin-VQUF3EEQ.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Twitter" href="https://twitter.com/bioprocessintl"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_layout"><span data-component="icon" data-name="Twitter" class="SocialShare-Icon SocialShare-Icon_variant_layout SocialShare-Icon_type_twitter" style="mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);-webkit-mask-image:url(/build/_assets/Twitter-WD5AOEQ7.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a><a target="_blank" rel="noreferrer" aria-label="Youtube" href="https://www.youtube.com/@bioprocessinternational2391"><span class="SocialShare-IconWrapper SocialShare-IconWrapper_variant_layout"><span data-component="icon" data-name="Youtube" class="SocialShare-Icon SocialShare-Icon_variant_layout SocialShare-Icon_type_youtube" style="mask-image:url(/build/_assets/Youtube-S4PSC4UA.svg);-webkit-mask-image:url(/build/_assets/Youtube-S4PSC4UA.svg);mask-repeat:no-repeat;-webkit-mask-repeat:no-repeat;-webkit-mask-position:center;-webkit-mask-size:contain"></span></span></a></div></div><div class="CopyrightsSection"><div class="CopyrightsSection-Background"></div><div data-testid="copyrights" class="CopyrightsSection-Wrapper"><a data-testid="businessUnit" class="CopyrightsSection-BusinessLink" target="_blank" href="https://informaconnect.com/"><img title="BPI Footer " data-component="image" class="CopyrightsSection-BusinessImage" data-src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt2d72d571f7fe7a8e/6553ad917b173f040a791328/BTYB_Informa_Connect_Logo_1Line_White_Grad_RGB.png?width=700&auto=webp&quality=80&disable=upscale" src="https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt2d72d571f7fe7a8e/6553ad917b173f040a791328/BTYB_Informa_Connect_Logo_1Line_White_Grad_RGB.png?width=700&auto=webp&quality=80&disable=upscale" loading="lazy" alt="BPI Footer "/></a><div class="CopyrightsSection-TextWrapper"><p data-testid="copyrightText" class="CopyrightsSection-Text"><span class="CopyrightsSection-TextBlock"></span>Copyright © 2024 Informa Connect Limited. Registered in England & Wales with number 01835199, registered office 5 Howick Place, London, SW1P 1WG.</p><div data-testid="copyrightLinks" class="CopyrightsSection-LinksWrapper CopyrightsSection-LinksWrapper_hasLinks"><a class="CopyrightsSection-Link" data-discover="true" href="/cookie-policy" target="_self">Cookie Policy<span class="CopyrightsSection-LinkSeparator">|</span></a><a class="CopyrightsSection-Link" rel="noreferrer" target="_blank" href="https://www.informa.com/privacy-policy/">Privacy<span class="CopyrightsSection-LinkSeparator">|</span></a><a class="CopyrightsSection-Link" rel="noreferrer" target="_blank" href="https://informaconnect.com/terms-of-use/">Terms<span class="CopyrightsSection-LinkSeparator">|</span></a><a class="CopyrightsSection-Link" rel="noreferrer" target="_blank" href="https://privacyportal-eu-cdn.onetrust.com/dsarwebform/c1f53e84-9f05-4169-a854-85052b63c50b/5f26b553-52cc-4973-a761-295d5634a6b6.html">CCPA: Do not sell my personal info</a></div></div></div></div></footer></div></div><div id="script-list"></div></main><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script>((STORAGE_KEY, restoreKey) => { if (!window.history.state || !window.history.state.key) { let key = Math.random().toString(32).slice(2); window.history.replaceState({ key }, ""); } try { let positions = JSON.parse(sessionStorage.getItem(STORAGE_KEY) || "{}"); let storedY = positions[restoreKey || window.history.state.key]; if (typeof storedY === "number") { window.scrollTo(0, storedY); } } catch (error) { console.error(error); sessionStorage.removeItem(STORAGE_KEY); } })("positions", null)</script><link rel="modulepreload" href="/build/manifest-A2F38A42.js"/><link rel="modulepreload" href="/build/entry.client-SFHSSSEN.js"/><link rel="modulepreload" href="/build/_shared/chunk-RVHE4U6B.js"/><link rel="modulepreload" href="/build/_shared/chunk-SJXV5VAW.js"/><link rel="modulepreload" href="/build/_shared/chunk-63EVRDSK.js"/><link rel="modulepreload" href="/build/_shared/chunk-ADMCF34Z.js"/><link rel="modulepreload" href="/build/_shared/chunk-QLNIWV7P.js"/><link rel="modulepreload" href="/build/_shared/chunk-VAILQJN5.js"/><link rel="modulepreload" href="/build/_shared/chunk-RZRUW7QG.js"/><link rel="modulepreload" href="/build/_shared/chunk-3MIG7PUI.js"/><link rel="modulepreload" href="/build/_shared/chunk-B7M2L5OV.js"/><link rel="modulepreload" href="/build/_shared/chunk-JWYSME77.js"/><link rel="modulepreload" href="/build/_shared/chunk-JRHR4PP4.js"/><link rel="modulepreload" href="/build/_shared/chunk-WTDTITBY.js"/><link rel="modulepreload" href="/build/_shared/chunk-VZQVWFLO.js"/><link rel="modulepreload" href="/build/_shared/chunk-4PCUPHYO.js"/><link rel="modulepreload" href="/build/_shared/chunk-JERMOH2I.js"/><link rel="modulepreload" href="/build/_shared/chunk-265XATAY.js"/><link rel="modulepreload" href="/build/_shared/chunk-5JUJG2OP.js"/><link rel="modulepreload" href="/build/_shared/chunk-BC6KZFPP.js"/><link rel="modulepreload" href="/build/_shared/chunk-QVUW3IXO.js"/><link rel="modulepreload" href="/build/_shared/chunk-ALTNKHHR.js"/><link rel="modulepreload" href="/build/_shared/chunk-HMGGHMSJ.js"/><link rel="modulepreload" href="/build/_shared/chunk-IW54JVOH.js"/><link rel="modulepreload" href="/build/root-TPDAOOC5.js"/><link rel="modulepreload" href="/build/_shared/chunk-BEXYKDRS.js"/><link rel="modulepreload" href="/build/_shared/chunk-ED7QE4BI.js"/><link rel="modulepreload" href="/build/_shared/chunk-JSR73AOE.js"/><link rel="modulepreload" href="/build/_shared/chunk-2GCGBGJC.js"/><link rel="modulepreload" href="/build/_shared/chunk-V2OXSPCY.js"/><link rel="modulepreload" href="/build/_shared/chunk-TMZP7SNL.js"/><link rel="modulepreload" href="/build/_shared/chunk-67BSXSX4.js"/><link rel="modulepreload" href="/build/_shared/chunk-AZ4H7HW6.js"/><link rel="modulepreload" href="/build/_shared/chunk-WJRCTNP6.js"/><link rel="modulepreload" href="/build/_shared/chunk-RF3GAYWA.js"/><link rel="modulepreload" href="/build/_shared/chunk-7IHSV4VV.js"/><link rel="modulepreload" href="/build/_shared/chunk-PLHCH5TH.js"/><link rel="modulepreload" href="/build/_shared/chunk-6GCYGCGB.js"/><link rel="modulepreload" href="/build/_shared/chunk-WGLVXOTX.js"/><link rel="modulepreload" href="/build/_shared/chunk-WXVEBWE3.js"/><link rel="modulepreload" href="/build/_shared/chunk-7WX3BG7O.js"/><link rel="modulepreload" href="/build/_shared/chunk-S6Q7UVRU.js"/><link rel="modulepreload" href="/build/_shared/chunk-2Q3IQPTU.js"/><link rel="modulepreload" href="/build/_shared/chunk-B765HE7O.js"/><link rel="modulepreload" href="/build/_shared/chunk-4DPVJM62.js"/><link rel="modulepreload" href="/build/_shared/chunk-PHSYQFSR.js"/><link rel="modulepreload" href="/build/_shared/chunk-GGO4FWBQ.js"/><link rel="modulepreload" href="/build/_shared/chunk-N3DN6AS5.js"/><link rel="modulepreload" href="/build/_shared/chunk-IJ353W5V.js"/><link rel="modulepreload" href="/build/_shared/chunk-C5UGRRW5.js"/><link rel="modulepreload" href="/build/_shared/chunk-KNORYGJC.js"/><link rel="modulepreload" href="/build/_shared/chunk-TDM4RAGW.js"/><link rel="modulepreload" href="/build/routes/$topic.$slug._index-J4IJ2FVO.js"/><script>window.__remixContext = {"future":{"v3_fetcherPersist":false,"v3_relativeSplatPath":false,"v3_throwAbortReason":false},"state":{"loaderData":{"root":{"brand":"bioprocessinternational","authenticationStatus":"anonymous","siteName":"BioProcess International","ads":{"networkId":21797463964,"parentAdUnit":"bioprocessintl.home","enabledAds":"all","checkClientIP":false,"disableSponsorBar":true,"welcAdOff":true},"authConfig":{"enabled":true,"authenticationConfigId":"a4a245652cad256461fe5c2eeb8ad5e0","disableCaptcha":false},"isDctsTurnOn":false,"oneTrust":{"siteId":"c0c70deb-8acc-4a4e-901a-bb865dd8f587"},"gtmIds":{"primary":"GTM-N49ZKQB","secondary":"GTM-NNQFN78H"},"ui":{"brand":"bioprocessinternational","theme":"theme1","font":{"primary":{"name":"Open Sans","url":"https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,500;0,600;0,700;0,800;1,300;1,400;1,500;1,600;1,700;1,800\u0026display=swap"},"secondary":{"name":"Open Sans","url":"https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,500;0,600;0,700;0,800;1,300;1,400;1,500;1,600;1,700;1,800\u0026display=swap"}}},"environment":"prod","featureToggles":{"elnNewsletter":false,"elnWithoutNewsletter":true,"iirisAuthentication":true,"subBrand":true,"useSettingsRedirectAPIVersion1":false,"gatingEnabled":true,"iirisRecommendationDisabled":false,"iasPetEnabled":false,"bridgedMediaEnabled":false,"ecommerceEnabled":false,"iirisRecommendationVer":"version4","weather3MonthForecastEnabled":false},"layout":{"socialLinks":[{"type":"Linkedin","url":"https://www.linkedin.com/company/bioprocess-international/"},{"type":"Twitter","url":"https://twitter.com/bioprocessintl"},{"type":"Youtube","url":"https://www.youtube.com/@bioprocessinternational2391"}],"informaBar":{"enabled":true,"leftSection":{"description":"BioProcess International is part of the Informa Connect Division of Informa PLC","subMenu":[{"title":"Informa PLC","url":"https://www.informa.com/"},{"title":"ABOUT US","url":"https://www.informa.com/about-us/"},{"title":"INVESTOR RELATIONS","url":"https://www.informa.com/investors/"},{"title":"TALENT","url":"https://www.informa.com/talent/"}]},"rightSection":{"description":"This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726."}},"nav":{"mainMenuItems":[{"title":"Upstream","url":"/upstream-processing","seeAllLink":"See all","seeAllLinkUrl":"/upstream-processing","hasSubMenu":true,"subMenu":[{"title":"Bioreactors","url":"/upstream-processing/bioreactors"},{"title":"Biochemicals/Raw Materials","url":"/upstream-processing/biochemicals-raw-materials"},{"title":"Cell Culture Media","url":"/upstream-processing/cell-culture-media"},{"title":"Expression Platforms","url":"/upstream-processing/expression-platforms"},{"title":"Microbial Cell Culture","url":"/upstream-processing/microbial-cell-culture"},{"title":"Perfusion Cell Culture","url":"/upstream-processing/perfusion-cell-culture"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta52221f8f722fb60/672252552ae2d2c25bd0eacc/10-29-2024-Croda-ATE-Slide-1.png","alt":"Croda Pharma Ask the Expert"},"articleName":"Introducing Super Refined™ Poloxamer 188: Optimized for Mammalian Cell Culture with Exceptional Batch-to-Batch Consistency","mobileHeadline":"Introducing Super Refined™ Poloxamer 188: Optimized for Mammalian Cell Culture with Exceptional Batch-to-Batch Consistency","articleSummary":"","articleUrl":"/sponsored-content/introducing-super-refined-poloxamer-188-optimized-for-mammalian-cell-culture-with-exceptional-batch-to-batch-consistency","listPageUrl":"/webinars","date":"Oct 29, 2024","webinarStartTime":"8:00 PDT","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":60,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltc2815fa9653283fb/66ec56123cc5b3b0a287d5df/CGT-Campaign-Key-Visual-Gene-B-0003477.jpg","alt":"Sartorius"},"articleName":"Building Reliability Into Scale-Up: Targeted Optimization for AAV Production","mobileHeadline":"Building Reliability Into Scale-Up: Targeted Optimization for AAV Production","articleSummary":"","articleUrl":"/sponsored-content/building-reliability-into-scale-up-targeted-optimization-for-aav-production","listPageUrl":"/webinars","date":"Sep 17, 2024","webinarStartTime":"8:00 PDT","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":40,"variant":"card-vertical","layoutVariant":"vertical"}]},{"title":"Downstream","url":"/downstream-processing","seeAllLink":"See all","seeAllLinkUrl":"/downstream-processing","hasSubMenu":true,"subMenu":[{"title":"Chromatography","url":"/downstream-processing/chromatography"},{"title":"Filtration","url":"/downstream-processing/filtration"},{"title":"Separation/Purification","url":"/downstream-processing/separation-purification"},{"title":"Viral Clearance","url":"/downstream-processing/viral-clearance"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb698dd10ce0fff78/673783e6bdac76bd103e868b/slide1.jpg","alt":"Bio-Rad Ask the Expert webcast"},"articleName":"Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges","mobileHeadline":"Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges","articleSummary":"","articleUrl":"/sponsored-content/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges","listPageUrl":"/webinars","date":"Nov 14, 2024","webinarStartTime":"8:00 PST","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":15,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt605950e2c84dbc27/673515e0f6be965b10392c86/AAE-MS_ad_image_1280x720.jpg","alt":"Cygnus AAE-MS"},"articleName":"AAE-MS™: A Powerful Method to Assess Host Cell Protein ELISA Fit for Purpose","mobileHeadline":"AAE-MS™: A Powerful Method to Assess Host Cell Protein ELISA Fit for Purpose","articleSummary":"","articleUrl":"/sponsored-content/aae-ms-a-powerful-method-to-assess-host-cell-protein-elisa-fit-for-purpose","listPageUrl":"/webinars","date":"Nov 13, 2024","webinarStartTime":"13:14 PST","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":35,"variant":"card-vertical","layoutVariant":"vertical"}]},{"title":"Manufacturing","url":"/manufacturing","seeAllLink":"See all","seeAllLinkUrl":"/manufacturing","hasSubMenu":true,"subMenu":[{"title":"Biosimilars","url":"/manufacturing/biosimilars"},{"title":"Continuous Bioprocessing","url":"/manufacturing/continuous-bioprocessing"},{"title":"Facility Design/Engineering","url":"/manufacturing/facility-design-engineering"},{"title":"Formulation","url":"/manufacturing/formulation"},{"title":"Single Use","url":"/manufacturing/single-use"},{"title":"Fill/Finish","url":"/manufacturing/fill-finish"},{"title":"Information Technology","url":"/manufacturing/information-technology"},{"title":"Process Monitoring and Controls","url":"/manufacturing/process-monitoring-and-controls"},{"title":"Supply Chain","url":"/manufacturing/supply-chain"},{"title":"Validation","url":"/manufacturing/validation"},{"title":"CMC Forums","url":"/manufacturing/cmc-forums"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3ebae85a29c14385/673e45cd6fac62187a4d0ec3/11-19-2024-908-ATE-Site-Image.jpg","alt":"908 Devices Ask the Expert"},"articleName":"Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality","mobileHeadline":"Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality","articleSummary":"","articleUrl":"/sponsored-content/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality","listPageUrl":"/webinars","date":"Nov 19, 2024","webinarStartTime":"8:00 PST","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":30,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt878d3807a987740f/6723e4f8ea57a35ffa463d42/10-31-2024-Lonza-ATE-Site.png","alt":"Lonza Ask the Expert "},"articleName":"Introduction to Lonza CHO Media Portfolio: Harnessing Simplicity with the TheraPRO® CHO Media System","mobileHeadline":"Introduction to Lonza CHO Media Portfolio: Harnessing Simplicity with the TheraPRO® CHO Media System","articleSummary":"","articleUrl":"/sponsored-content/introduction-to-lonza-cho-media-portfolio-harnessing-simplicity-with-the-therapro-cho-media-system","listPageUrl":"/webinars","date":"Oct 31, 2024","webinarStartTime":"8:00 PDT","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":50,"variant":"card-vertical","layoutVariant":"vertical"}]},{"title":"Analytical","url":"/analytical","seeAllLink":"See all","seeAllLinkUrl":"/analytical","hasSubMenu":true,"subMenu":[{"title":"QA/QC","url":"/analytical/qa-qc"},{"title":"Cell Line Development","url":"/analytical/cell-line-development"},{"title":"PAT","url":"/analytical/pat"},{"title":"Product Characterization","url":"/analytical/product-characterization"},{"title":"Bioanalytical Methods","url":"/analytical/bioanalytical-methods"},{"title":"Process Development","url":"/analytical/process-development"},{"title":"Assays","url":"/analytical/assays"},{"title":"Laboratory Equipment","url":"/analytical/laboratory-equipment"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt7b0c2947a2efe76d/672d2be95b6a903e77a85126/11-07-2024-ValGenesis-ATE-Slide1.png","alt":"ValGenesis Ask the Expert webinar"},"articleName":"Out of the Box Computer Software Assurance with ValGenesis VLMS","mobileHeadline":"Out of the Box Computer Software Assurance with ValGenesis VLMS","articleSummary":"","articleUrl":"/sponsored-content/out-of-the-box-computer-software-assurance-with-valgenesis-vlms","listPageUrl":"/webinars","date":"Nov 7, 2024","webinarStartTime":"8:00 PST","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":30,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt75859230194dee02/66ec682af99b3a803310a90f/S-testify_.png","alt":"Samsung S-Tesify"},"articleName":"Innovative Approaches to Enhance Cell Culture Density for High-Quality Production","mobileHeadline":"Innovative Approaches to Enhance Cell Culture Density for High-Quality Production","articleSummary":"","articleUrl":"/sponsored-content/innovative-approaches-to-enhance-cell-culture-density-for-high-quality-production","listPageUrl":"/webinars","date":"Sep 19, 2024","webinarStartTime":"8:00 PDT","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":15,"variant":"card-vertical","layoutVariant":"vertical"}]},{"title":"Business","url":"/business","seeAllLink":"See all","seeAllLinkUrl":"/business","hasSubMenu":true,"subMenu":[{"title":"Bioregions","url":"/business/bioregions"},{"title":"Careers \u0026 Training","url":"/business/careers-training"},{"title":"Contract Services","url":"/business/contract-services"},{"title":"Economics","url":"/business/economics"},{"title":"Pre-Clinical \u0026 Clinical Trials","url":"/business/pre-clinical-and-clinical-trials"},{"title":"Risk Management","url":"/business/risk-management"},{"title":"Intellectual Property","url":"/business/intellectual-property"},{"title":"Regulatory Affairs","url":"/business/regulatory-affairs"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltcc8e38b7538dbf25/6740f228fbc6d82586601064/11-21-2024-Lonza-ATE-slide1.png","alt":"Lonza Ask the Expert webcast"},"articleName":"Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality","mobileHeadline":"Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality","articleSummary":"","articleUrl":"/sponsored-content/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality","listPageUrl":"/webinars","date":"Nov 21, 2024","webinarStartTime":"8:00 PST","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":30,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt20f52ba8f95fc0cb/66b50b3ce4286a875cff8015/AdobeStock_708481111.jpeg","alt":""},"articleName":"Key strategies for effective technology evaluation","mobileHeadline":"Key strategies for effective technology evaluation","articleSummary":"To maintain a competitive edge, life science organizations must leverage technology to enhance decision-making, create innovative business models, and improve customer experiences. ","articleUrl":"/bioprocess-insider/key-strategies-for-effective-technology-evaluation","listPageUrl":"","date":"Aug 8, 2024","webinarStartTime":"","categoryName":"Bioprocess Insider","categoryUrl":"/bioprocess-insider","contentType":"Article","contributors":[{"name":"Kim Bennett","link":"/author/kim-bennett","avatar":""}],"timeRead":2,"variant":"card-vertical","layoutVariant":"vertical"}]},{"title":"Therapeutic Modalities","url":"/therapeutic-modalities","seeAllLink":"See all","seeAllLinkUrl":"/therapeutic-modalities","hasSubMenu":true,"subMenu":[{"title":"Cell Therapies","url":"/therapeutic-modalities/cell-therapies"},{"title":"Emerging Therapeutics","url":"/therapeutic-modalities/emerging-therapeutics-manufacturing"},{"title":"Gene Therapies","url":"/therapeutic-modalities/gene-therapies"},{"title":"Large Molecule Development","url":"/therapeutic-modalities/large-molecule-development"},{"title":"MAb","url":"/therapeutic-modalities/monoclonal-antibodies"},{"title":"Personalized Medicine","url":"/therapeutic-modalities/personalized-medicine"},{"title":"Vaccines","url":"/therapeutic-modalities/vaccines"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb399cef493535335/6709708e7bf3c7af797141d0/10-10-2024-Roche-ATE-Site-Image.png","alt":"Roche ATE webinar"},"articleName":"Decoding AAV Manufacturing: Navigating Critical Quality Attributes and their Analytics","mobileHeadline":"Decoding AAV Manufacturing: Navigating Critical Quality Attributes and their Analytics","articleSummary":"","articleUrl":"/sponsored-content/decoding-aav-manufacturing-navigating-critical-quality-attributes-and-their-analytics","listPageUrl":"/webinars","date":"Oct 11, 2024","webinarStartTime":"8:00 PDT","categoryName":"Sponsored Content","categoryUrl":"/sponsored-content","contentType":"Webinar","contributors":[{"name":"BPI Contributor","link":"/author/bpi-contributor","avatar":""}],"timeRead":20,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt4464ea4100e2a8de/66a1392f540b829bcab36cd2/AdobeStock_320918695.jpeg","alt":""},"articleName":"Biomanufacturing in space accelerating therapy development on Earth","mobileHeadline":"Biomanufacturing in space accelerating therapy development on Earth","articleSummary":"The International Space Station (ISS) is hosting a live webinar on Friday, 26 July that will discuss upcoming scientific investigations that are launching on Northrop Grumman's 21st Commercial Resupply Services mission. Speakers will discuss life science applications such as biomanufacturing in space. ","articleUrl":"/bioprocess-insider/biomanufacturing-in-space-accelerating-therapy-development-on-earth","listPageUrl":"","date":"Jul 24, 2024","webinarStartTime":"","categoryName":"Bioprocess Insider","categoryUrl":"/bioprocess-insider","contentType":"Article","contributors":[{"name":"Josh Abbott","link":"/author/josh-abbott","avatar":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt29e23dbf14e04f37/671125d8ae0aeeb6c7fa3d24/head1.jpg"}],"timeRead":3,"variant":"card-vertical","layoutVariant":"vertical"}]},{"title":"BioProcess Insider","url":"/bioprocess-insider","seeAllLink":"See all","seeAllLinkUrl":"/bioprocess-insider","hasSubMenu":true,"subMenu":[{"title":"Deal-Making","url":"bioprocess-insider/deal-making"},{"title":"Facilities \u0026 Capacity","url":"/bioprocess-insider/facilities-capacity"},{"title":"Global Markets","url":"/bioprocess-insider/global-markets"},{"title":"Regulations","url":"/bioprocess-insider/regulations"},{"title":"Therapeutic Class","url":"/bioprocess-insider/therapeutic-class"},{"title":"Upstream \u0026 Downstream Processing","url":"/bioprocess-insider/upstream-downstream-processing"},{"title":"Webcasts","url":"/bioprocess-insider/webcasts"},{"title":"BioProcess Insider Podcasts","url":"/bioprocess-insider/bpi-podcasts"}],"recentContents":[{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3cc2b4da01031668/6740715c0ab0261fd1630099/m_and_a_timbrk.jpg","alt":""},"articleName":"Halozyme’s $2.1bn Evotec bid: First the ins, now the out","mobileHeadline":"Halozyme’s $2.1bn Evotec bid: First the ins, now the out","articleSummary":"The proposed acquisition of Evotec, which would have transformed Halozyme from a therapeutics-based drug delivery platform into a full bioprocess services company, has been withdrawn. ","articleUrl":"/deal-making/halozyme-eyes-continuous-manufacturing-platform-in-2-1bn-evotec-bid","listPageUrl":"","date":"Nov 25, 2024","webinarStartTime":"","categoryName":"Deal-Making","categoryUrl":"/bioprocess-insider/deal-making","contentType":"Article","contributors":[{"name":"Dan Stanton","link":"/author/dan-stanton","avatar":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg"}],"timeRead":3,"variant":"card-vertical","layoutVariant":"vertical"},{"thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt67fc0d78c80e874f/673f28ede1e4f3389fa4a35e/manufacturing_deal_Wavebreakmedia.jpg","alt":""},"articleName":"CDMO success stories: News from Lonza, Samsung Bio, Fujifilm","mobileHeadline":"CDMO success stories: News from Lonza, Samsung Bio, Fujifilm","articleSummary":"Fujifilm Diosynth expands a cell therapy facility in California, Lonza produces first GMP batches from New Hampshire plant, and Samsung Biologics signs $688 million seven-year contract. Welcome to our big CDMO round-up.","articleUrl":"/deal-making/cdmo-success-stories-news-from-lonza-samsung-bio-fujifilm","listPageUrl":"","date":"Nov 21, 2024","webinarStartTime":"","categoryName":"Deal-Making","categoryUrl":"/bioprocess-insider/deal-making","contentType":"Article","contributors":[{"name":"Dan Stanton","link":"/author/dan-stanton","avatar":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg"}],"timeRead":3,"variant":"card-vertical","layoutVariant":"vertical"}]}],"secondaryMenu":[{"title":"BPI Events","url":"https://informaconnect.com/bioprocess-international-events/?utm_source=bpi-publication\u0026utm_medium=top-menu"},{"title":"About","url":"/about"},{"title":"Subscribe","url":"https://magazine.bioprocessintl.com/?pk=WEBS23B"},{"title":"Contribute","url":"/contribute"}]},"megaMenu":{"largeMenu":[{"title":"Upstream","url":"/upstream-processing","subMenu":[{"title":"Bioreactors","url":"/upstream-processing/bioreactors"},{"title":"Biochemicals/Raw Materials","url":"/upstream-processing/biochemicals-raw-materials"},{"title":"Cell Culture Media","url":"/upstream-processing/cell-culture-media"},{"title":"Expression Platforms","url":"/upstream-processing/expression-platforms"},{"title":"Microbial Cell Culture","url":"/upstream-processing/microbial-cell-culture"},{"title":"Perfusion Cell Culture","url":"/upstream-processing/perfusion-cell-culture"}],"seeAllLink":"See all","seeAllLinkUrl":"/upstream-processing"},{"title":"Downstream","url":"/downstream-processing","subMenu":[{"title":"Chromatography","url":"/downstream-processing/chromatography"},{"title":"Filtration","url":"/downstream-processing/filtration"},{"title":"Separation/Purification","url":"/downstream-processing/separation-purification"},{"title":"Viral Clearance","url":"/downstream-processing/viral-clearance"}],"seeAllLink":"See all","seeAllLinkUrl":"/downstream-processing"},{"title":"Manufacturing","url":"/manufacturing","subMenu":[{"title":"Biosimilars","url":"/manufacturing/biosimilars"},{"title":"Continuous Bioprocessing","url":"/manufacturing/continuous-bioprocessing"},{"title":"Facility Design/Engineering","url":"/manufacturing/facility-design-engineering"},{"title":"Formulation","url":"/manufacturing/formulation"},{"title":"Single Use","url":"/manufacturing/single-use"},{"title":"Fill/Finish","url":"/manufacturing/fill-finish"},{"title":"Information Technology","url":"/manufacturing/information-technology"},{"title":"Process Monitoring and Controls","url":"/manufacturing/process-monitoring-and-controls"},{"title":"Supply Chain","url":"/manufacturing/supply-chain"},{"title":"Validation","url":"/manufacturing/validation"},{"title":"CMC Forums","url":"/manufacturing/cmc-forums"}],"seeAllLink":"See all","seeAllLinkUrl":"/manufacturing"},{"title":"Analytical","url":"/analytical","subMenu":[{"title":"QA/QC","url":"/analytical/qa-qc"},{"title":"Cell Line Development","url":"/analytical/cell-line-development"},{"title":"PAT","url":"/analytical/pat"},{"title":"Product Characterization","url":"/analytical/product-characterization"},{"title":"Bioanalytical Methods","url":"/analytical/bioanalytical-methods"},{"title":"Process Development","url":"/analytical/process-development"},{"title":"Assays","url":"/analytical/assays"},{"title":"Laboratory Equipment","url":"/analytical/laboratory-equipment"}],"seeAllLink":"See all","seeAllLinkUrl":"/analytical"},{"title":"Business","url":"/business","subMenu":[{"title":"Bioregions","url":"/business/bioregions"},{"title":"Careers \u0026 Training","url":"/business/careers-training"},{"title":"Contract Services","url":"/business/contract-services"},{"title":"Economics","url":"/business/economics"},{"title":"Pre-Clinical \u0026 Clinical Trials","url":"/business/pre-clinical-and-clinical-trials"},{"title":"Risk Management","url":"/business/risk-management"},{"title":"Intellectual Property","url":"/business/intellectual-property"},{"title":"Regulatory Affairs","url":"/business/regulatory-affairs"}],"seeAllLink":"See all","seeAllLinkUrl":"/business"},{"title":"Therapeutic Modalities","url":"/therapeutic-modalities","subMenu":[{"title":"Cell Therapies","url":"/therapeutic-modalities/cell-therapies"},{"title":"Emerging Therapeutics","url":"/therapeutic-modalities/emerging-therapeutics-manufacturing"},{"title":"Gene Therapies","url":"/therapeutic-modalities/gene-therapies"},{"title":"Large Molecule Development","url":"/therapeutic-modalities/large-molecule-development"},{"title":"MAb","url":"/therapeutic-modalities/monoclonal-antibodies"},{"title":"Personalized Medicine","url":"/therapeutic-modalities/personalized-medicine"},{"title":"Vaccines","url":"/therapeutic-modalities/vaccines"}],"seeAllLink":"See all","seeAllLinkUrl":"/therapeutic-modalities"},{"title":"BioProcess Insider","url":"/bioprocess-insider","subMenu":[{"title":"Deal-Making","url":"bioprocess-insider/deal-making"},{"title":"Facilities \u0026 Capacity","url":"/bioprocess-insider/facilities-capacity"},{"title":"Global Markets","url":"/bioprocess-insider/global-markets"},{"title":"Regulations","url":"/bioprocess-insider/regulations"},{"title":"Therapeutic Class","url":"/bioprocess-insider/therapeutic-class"},{"title":"Upstream \u0026 Downstream Processing","url":"/bioprocess-insider/upstream-downstream-processing"},{"title":"Webcasts","url":"/bioprocess-insider/webcasts"},{"title":"BioProcess Insider Podcasts","url":"/bioprocess-insider/bpi-podcasts"}],"seeAllLink":"See all","seeAllLinkUrl":"/bioprocess-insider"}],"smallMenu":[{"title":"Resources","url":"","subMenu":[{"title":"Issue Archive","url":"/publications"},{"title":"Featured Reports","url":"/publications/featured-reports"},{"title":"eBooks","url":"/publications/ebooks/ebooks"},{"title":"Special Reports","url":"/publications/special-reports/special-reports"},{"title":"Webinars","url":"/webinars"},{"title":"White Papers","url":"/program/white-papers"},{"title":"Videos","url":"/videos"},{"title":"Posters","url":"/program/poster-hall"}]},{"title":"Events","url":"","subMenu":[{"title":"Cell \u0026 Gene Therapy Europe","url":"https://informaconnect.com/celltherapy/?vip_code=BPIPUB\u0026utm_source=bpi-publication\u0026utm_medium=web-navigation"},{"title":"Biomanufacturing Ireland","url":"https://informaconnect.com/commercial-biomanufacturing-ireland/?vip_code=BPIPUB\u0026utm_source=bpi-publication\u0026utm_medium=web-navigation"},{"title":"BioProcess International West","url":"https://informaconnect.com/bpi-west/?vip_code=BPIPUB\u0026utm_source=bpi-publication\u0026utm_medium=web-navigation"},{"title":"BioProcess International Europe","url":"https://informaconnect.com/bpieurope/?vip_code=BPIPUB\u0026utm_source=bpi-publication\u0026utm_medium=web-navigation"},{"title":"BioProcess International Boston","url":"https://informaconnect.com/bioprocessinternational?vip_code=bpipub\u0026utm_source=bpi-publication\u0026utm_medium=web-menu"},{"title":"Cell \u0026 Gene Therapy US","url":"https://informaconnect.com/cell-therapy-bioprocessing?vip_code=bpipub\u0026utm_source=bpi-publication\u0026utm_medium=web-menu"},{"title":"BioProcess International Academy","url":"https://informaconnect.com/bioprocess-international-events/bioprocess-international-virtual-events/?vip_code=BPIPUB\u0026utm_source=bpi-publication\u0026utm_medium=web-navigation"},{"title":"Industry Events","url":"/events"}]},{"title":"About BPI","url":"","subMenu":[{"title":"Contribute","url":"/contribute"},{"title":"Advertise","url":"https://get.informaconnect.com/bpipublication/sponsorship/?utm_source=BioprocessIntl\u0026utm_medium=web\u0026utm_campaign=advertise"},{"title":"Contact Us","url":"/about"}]}],"sideNavSections":[]},"navBase":{"logo":{"url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta6717ea597e88ac9/6540ff1e76ec82040a90a249/BPI_-_Logo.svg","altText":""}},"footer":{"logo":{"url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blta6717ea597e88ac9/6540ff1e76ec82040a90a249/BPI_-_Logo.svg","altText":"BioProcess International logo"},"linkSections":[{"links":[{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"BPI Archive","url":"/publications"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"BioProcess Insider News","url":"/program/bioprocess-insider"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":true,"title":"Subscribe to BioProcess Insider Newsletter","url":"https://bpi.bioprocessintl.com/bioprocess-insider-subscription"}],"title":"BPI Content","type":"1"},{"links":[{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Events","url":"/events"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Webinars","url":"/webinars"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"White Papers","url":"/program/white-papers"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Posters","url":"/program/poster-hall"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Videos","url":"/videos"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Podcasts","url":"/podcasts"}],"title":"Resources","type":"1"},{"links":[{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Who We Are","url":"/about"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Editorial Advisors","url":"/editorial-advisors"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":false,"title":"Author Guidelines","url":"/contribute"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":true,"title":"Advertising/Media Kit","url":"https://get.informaconnect.com/bpipublication/sponsorship/?utm_source=BioprocessIntl\u0026utm_medium=web\u0026utm_campaign=advertise"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":true,"title":"List Rental/Reprints","url":"/reprints-and-list-rental"},{"image":{"altText":"","url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltb5e939f70259682f/6540de06ff10ba040a7e8576/BPI_LOGO_COLOR.png"},"openInNewTab":true,"title":"Careers","url":"https://informaconnect.com/careers/"}],"title":"About BPI","type":"1"}],"brandLinks":[],"copyright":{"businessUnit":{"url":"https://informaconnect.com/","name":"BPI Footer ","logoUrl":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt2d72d571f7fe7a8e/6553ad917b173f040a791328/BTYB_Informa_Connect_Logo_1Line_White_Grad_RGB.png"},"links":[{"image":{"altText":"Cookie Policy","url":"/cookie-policy"},"openInNewTab":false,"title":"Cookie Policy","url":"/cookie-policy"},{"image":{"altText":"Privacy","url":"https://www.informa.com/privacy-policy/"},"openInNewTab":true,"title":"Privacy","url":"https://www.informa.com/privacy-policy/"},{"image":{"altText":"Terms","url":"https://informaconnect.com/terms-of-use/"},"openInNewTab":true,"title":"Terms","url":"https://informaconnect.com/terms-of-use/"},{"image":{"altText":"CCPA: Do not sell my personal info","url":"https://privacyportal-eu-cdn.onetrust.com/dsarwebform/c1f53e84-9f05-4169-a854-85052b63c50b/5f26b553-52cc-4973-a761-295d5634a6b6.html"},"openInNewTab":true,"title":"CCPA: Do not sell my personal info","url":"https://privacyportal-eu-cdn.onetrust.com/dsarwebform/c1f53e84-9f05-4169-a854-85052b63c50b/5f26b553-52cc-4973-a761-295d5634a6b6.html"}],"title":" Informa Connect Limited. Registered in England \u0026 Wales with number 01835199, registered office 5 Howick Place, London, SW1P 1WG."}},"isSponsorBarEnabled":true,"isPaidContent":false},"newRelicJs":"window.NREUM||(NREUM={});NREUM.init={distributed_tracing:{enabled:true},privacy:{cookies_enabled:true},ajax:{deny_list:[\"bam.eu01.nr-data.net\"]}};\n\n;NREUM.loader_config={accountID:\"3936348\",trustKey:\"3288925\",agentID:\"538600195\",licenseKey:\"NRJS-26ae6a3b09493bbcc87\",applicationID:\"538600195\"};\n;NREUM.info={beacon:\"bam.eu01.nr-data.net\",errorBeacon:\"bam.eu01.nr-data.net\",licenseKey:\"NRJS-26ae6a3b09493bbcc87\",applicationID:\"538600195\",sa:1};\n;/*! For license information please see nr-loader-spa-1.274.0.min.js.LICENSE.txt */\n(()=\u003e{var e,t,r={8122:(e,t,r)=\u003e{\"use strict\";r.d(t,{a:()=\u003ei});var n=r(944);function i(e,t){try{if(!e||\"object\"!=typeof e)return(0,n.R)(3);if(!t||\"object\"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])\u0026\u0026Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):\"object\"==typeof e[a]\u0026\u0026\"object\"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=\u003e{\"use strict\";r.d(t,{Vp:()=\u003ec,fn:()=\u003es,x1:()=\u003eu});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey\u0026\u0026!!t.errorBeacon\u0026\u0026!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error(\"All info objects require an agent identifier!\");if(!a[e])throw new Error(\"Info for \".concat(e,\" was never set\"));return a[e]}function u(e,t){if(!e)throw new Error(\"All info objects require an agent identifier!\");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r\u0026\u0026(r.info=a[e])}},9417:(e,t,r)=\u003e{\"use strict\";r.d(t,{D0:()=\u003eh,gD:()=\u003eg,xN:()=\u003ep});var n=r(993);const i=e=\u003e{if(!e||\"string\"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const u=\"[data-nr-mask]\",d=()=\u003e{const e={mask_selector:\"*\",block_selector:\"[data-nr-block]\",mask_input_options:{color:!1,date:!1,\"datetime-local\":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector=\"\".concat(t,\",\").concat(u):\"\"===t||null===t?e.mask_selector=u:(0,a.R)(5,t)},get block_class(){return\"nr-block\"},get ignore_class(){return\"nr-ignore\"},get mask_text_class(){return\"nr-mask\"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=\",\".concat(t):\"\"!==t\u0026\u0026(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t\u0026\u0026\"object\"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f=\"All configuration objects require an agent identifier!\";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error(\"Configuration for \".concat(e,\" was never set\"));return l[e]}function p(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,d());const r=(0,s.nY)(e);r\u0026\u0026(r.init=l[e])}function g(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split(\".\"),i=0;i\u003cn.length-1;i++)if(\"object\"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=\u003e{\"use strict\";r.d(t,{a:()=\u003ec,o:()=\u003es});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error(\"All loader-config objects require an agent identifier!\");if(!a[e])throw new Error(\"LoaderConfig for \".concat(e,\" was never set\"));return a[e]}function c(e,t){if(!e)throw new Error(\"All loader-config objects require an agent identifier!\");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r\u0026\u0026(r.loader_config=a[e])}},3371:(e,t,r)=\u003e{\"use strict\";r.d(t,{V:()=\u003ef,f:()=\u003el});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},u={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},d={};function l(e){if(!e)throw new Error(\"All runtime objects require an agent identifier!\");if(!d[e])throw new Error(\"Runtime for \".concat(e,\" was never set\"));return d[e]}function f(e,t){if(!e)throw new Error(\"All runtime objects require an agent identifier!\");d[e]={...(0,n.a)(t,u),...c},Object.hasOwnProperty.call(d[e],\"harvestCount\")||Object.defineProperty(d[e],\"harvestCount\",{get:()=\u003e++s});const r=(0,i.nY)(e);r\u0026\u0026(r.runtime=d[e])}},9324:(e,t,r)=\u003e{\"use strict\";r.d(t,{F3:()=\u003ei,Xs:()=\u003eo,Yq:()=\u003ea,xv:()=\u003en});const n=\"1.274.0\",i=\"PROD\",o=\"CDN\",a=\"^2.0.0-alpha.17\"},6154:(e,t,r)=\u003e{\"use strict\";r.d(t,{A4:()=\u003es,OF:()=\u003ed,RI:()=\u003ei,WN:()=\u003eh,bv:()=\u003eo,gm:()=\u003ea,lR:()=\u003ef,m:()=\u003eu,mw:()=\u003ec,sb:()=\u003el});var n=r(1863);const i=\"undefined\"!=typeof window\u0026\u0026!!window.document,o=\"undefined\"!=typeof WorkerGlobalScope\u0026\u0026(\"undefined\"!=typeof self\u0026\u0026self instanceof WorkerGlobalScope\u0026\u0026self.navigator instanceof WorkerNavigator||\"undefined\"!=typeof globalThis\u0026\u0026globalThis instanceof WorkerGlobalScope\u0026\u0026globalThis.navigator instanceof WorkerNavigator),a=i?window:\"undefined\"!=typeof WorkerGlobalScope\u0026\u0026(\"undefined\"!=typeof self\u0026\u0026self instanceof WorkerGlobalScope\u0026\u0026self||\"undefined\"!=typeof globalThis\u0026\u0026globalThis instanceof WorkerGlobalScope\u0026\u0026globalThis),s=\"complete\"===a?.document?.readyState,c=Boolean(\"hidden\"===a?.document?.visibilityState),u=\"\"+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),l=d\u0026\u0026\"undefined\"==typeof SharedWorker,f=(()=\u003e{const e=a.navigator?.userAgent?.match(/Firefox[/\\s](\\d+\\.\\d+)/);return Array.isArray(e)\u0026\u0026e.length\u003e=2?+e[1]:0})(),h=Date.now()-(0,n.t)()},7295:(e,t,r)=\u003e{\"use strict\";r.d(t,{Xv:()=\u003ea,gX:()=\u003ei,iW:()=\u003eo});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t\u003cn.length;t++){var r=n[t];if(\"*\"===r.hostname)return!1;if(s(r.hostname,e.hostname)\u0026\u0026c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e\u0026\u0026e.length)for(var t=0;t\u003ce.length;t++){let r=e[t];if(!r)continue;0===r.indexOf(\"http://\")?r=r.substring(7):0===r.indexOf(\"https://\")\u0026\u0026(r=r.substring(8));const i=r.indexOf(\"/\");let o,a;i\u003e0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a=\"\");let[s]=o.split(\":\");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length\u003et.length)\u0026\u0026t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf(\"/\")\u0026\u0026(e=e.substring(1)),0===t.indexOf(\"/\")\u0026\u0026(t=t.substring(1)),\"\"===e||e===t}},1687:(e,t,r)=\u003e{\"use strict\";r.d(t,{Ak:()=\u003ec,Ze:()=\u003el,x3:()=\u003eu});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};d(e),s[e].get(t)||s[e].set(t,r)}function u(e,t){e\u0026\u0026s[e]\u0026\u0026(s[e].get(t)\u0026\u0026s[e].delete(t),h(e,t,!1),s[e].size\u0026\u0026f(e))}function d(e){if(!e)throw new Error(\"agentIdentifier required\");s[e]||(s[e]=new Map)}function l(e=\"\",t=\"feature\",r=!1){if(d(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=\u003et.staged))\u0026\u0026(t.sort(((e,t)=\u003ee[1].priority-t[1].priority)),t.forEach((([t])=\u003e{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted\u0026\u0026o.backlog\u0026\u0026s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e\u0026\u0026t\u003ce.length;++t)p(e[t],r);Object.entries(r).forEach((([e,t])=\u003e{Object.values(t||{}).forEach((t=\u003e{t[0]?.on\u0026\u0026t[0]?.context()instanceof a.y\u0026\u0026t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit(\"drain-\"+t,[])}}function p(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=\u003e{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=\u003e{\"use strict\";r.d(t,{P:()=\u003ec,ee:()=\u003eu});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c=\"nr@context:\".concat(s.W),u=function e(t,r){var n={},s={},d={},l=!1;try{l=16===r.length\u0026\u0026(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:p,addEventListener:p,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i\u003cr.length;i++)r[i]===t\u0026\u0026r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o\u0026\u0026(o=!0);if(u.aborted\u0026\u0026!i)return;t\u0026\u0026o\u0026\u0026t.emit(e,r,n);for(var a=h(n),c=g(e),d=c.length,l=0;l\u003cd;l++)c[l].apply(a,r);var p=v()[s[e]];p\u0026\u0026p.push([f,e,r,a]);return a},get:m,listeners:g,context:h,buffer:function(e,t){const r=v();if(t=t||\"feature\",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=\u003e{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=\u003e{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t\u0026\u0026\"object\"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,\"aborted\",{get:()=\u003e{let e=f._aborted||!1;return e||(t\u0026\u0026(e=t.aborted),e)}}),f;function h(e){return e\u0026\u0026e instanceof a.y?e:e?(0,i.I)(e,c,(()=\u003enew a.y(c))):new a.y(c)}function p(e,t){n[e]=g(e).concat(t)}function g(e){return n[e]||[]}function m(t){return d[t]=d[t]||e(f,t)}function v(){return f.backlog}}(void 0,\"globalEE\"),d=(0,n.Zm)();d.ee||(d.ee=u)},2646:(e,t,r)=\u003e{\"use strict\";r.d(t,{y:()=\u003en});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=\u003e{\"use strict\";r.d(t,{d:()=\u003en,p:()=\u003ei});var n=r(7836).ee.get(\"handle\");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=\u003e{\"use strict\";r.d(t,{i:()=\u003eo});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o=\"feature\"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=\u003e{\"use strict\";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=\u003eo,jT:()=\u003en,sp:()=\u003ei})},5607:(e,t,r)=\u003e{\"use strict\";r.d(t,{W:()=\u003en});const n=(0,r(9566).bz)()},9566:(e,t,r)=\u003e{\"use strict\";r.d(t,{LA:()=\u003es,ZF:()=\u003ec,bz:()=\u003ea,el:()=\u003eu});var n=r(6154);const i=\"xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx\";function o(e,t){return e?15\u0026e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e\u0026\u0026e.getRandomValues\u0026\u0026(t=e.getRandomValues(new Uint8Array(30))),i.split(\"\").map((e=\u003e\"x\"===e?o(t,r++).toString(16):\"y\"===e?(3\u0026o()|8).toString(16):e)).join(\"\")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t\u0026\u0026t.getRandomValues\u0026\u0026(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s\u003ce;s++)a.push(o(r,i++).toString(16));return a.join(\"\")}function c(){return s(16)}function u(){return s(32)}},2614:(e,t,r)=\u003e{\"use strict\";r.d(t,{BB:()=\u003ea,H3:()=\u003en,g:()=\u003eu,iL:()=\u003ec,tS:()=\u003es,uh:()=\u003ei,wk:()=\u003eo});const n=\"NRBA\",i=\"SESSION\",o=144e5,a=18e5,s={STARTED:\"session-started\",PAUSE:\"session-pause\",RESET:\"session-reset\",RESUME:\"session-resume\",UPDATE:\"session-update\"},c={SAME_TAB:\"same-tab\",CROSS_TAB:\"cross-tab\"},u={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=\u003e{\"use strict\";function n(){return Math.floor(performance.now())}r.d(t,{t:()=\u003en})},7485:(e,t,r)=\u003e{\"use strict\";r.d(t,{D:()=\u003ei});var n=r(6154);function i(e){if(0===(e||\"\").indexOf(\"data:\"))return{protocol:\"data\"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(\":\")),sameOrigin:t.protocol===n.gm?.location?.protocol\u0026\u0026t.host===n.gm?.location?.host};return r.port\u0026\u0026\"\"!==r.port||(\"http:\"===t.protocol\u0026\u0026(r.port=\"80\"),\"https:\"===t.protocol\u0026\u0026(r.port=\"443\")),r.pathname\u0026\u0026\"\"!==r.pathname?r.pathname.startsWith(\"/\")||(r.pathname=\"/\".concat(r.pathname)):r.pathname=\"/\",r}catch(e){return{}}}},944:(e,t,r)=\u003e{\"use strict\";function n(e,t){\"function\"==typeof console.debug\u0026\u0026console.debug(\"New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#\".concat(e),t)}r.d(t,{R:()=\u003en})},5284:(e,t,r)=\u003e{\"use strict\";r.d(t,{t:()=\u003ec,B:()=\u003es});var n=r(7836),i=r(6154);const o=\"newrelic\";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e\u0026\u0026\"object\"==typeof e\u0026\u0026(a.has(t)||(r.emit(\"rumresp\",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=\u003e{\"use strict\";r.d(t,{I:()=\u003ei});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty\u0026\u0026Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=\u003e{\"use strict\";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=\u003e{n\u0026\u0026void 0===i\u0026\u0026(e.apply(this,r),i=setTimeout((()=\u003e{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=\u003e{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=\u003e{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=\u003ei,s:()=\u003en})},3304:(e,t,r)=\u003e{\"use strict\";r.d(t,{A:()=\u003eo});var n=r(7836);const i=()=\u003e{const e=new WeakSet;return(t,r)=\u003e{if(\"object\"==typeof r\u0026\u0026null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??\"\"}catch(e){try{n.ee.emit(\"internal-error\",[e])}catch(e){}return\"\"}}},5289:(e,t,r)=\u003e{\"use strict\";r.d(t,{GG:()=\u003eo,sB:()=\u003ea});var n=r(3878);function i(){return\"undefined\"==typeof document||\"complete\"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)(\"load\",e,t)}function a(e){if(i())return e();(0,n.DD)(\"DOMContentLoaded\",e)}},384:(e,t,r)=\u003e{\"use strict\";r.d(t,{NT:()=\u003eo,US:()=\u003ed,Zm:()=\u003ea,bQ:()=\u003ec,dV:()=\u003es,nY:()=\u003eu,pV:()=\u003el});var n=r(6154),i=r(1863);const o={beacon:\"bam.nr-data.net\",errorBeacon:\"bam.nr-data.net\"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic\u0026\u0026(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function u(e){let t=a();return t.initializedAgents?.[e]}function d(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=\u003e{\"use strict\";r.d(t,{u:()=\u003ei});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)(\"visibilitychange\",(function(){if(t)return void(\"hidden\"===document.visibilityState\u0026\u0026e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=\u003e{\"use strict\";r.d(t,{u:()=\u003ef});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,u=\"addEventListener\",d=\"removeEventListener\",l=\"nr@wrapped:\".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get(\"events\")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[u,d],\"-\",p)}function p(e,t){return e[1]}return\"getPrototypeOf\"in Object\u0026\u0026(a.RI\u0026\u0026h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(u+\"-start\",(function(e,t){var n=e[1];if(null!==n\u0026\u0026(\"function\"==typeof n||\"object\"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if(\"function\"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,\"fn-\",null,e.name||\"anonymous\"):n}));this.wrapped=e[1]=i}})),t.on(d+\"-start\",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;\"object\"==typeof n\u0026\u0026!Object.prototype.hasOwnProperty.call(n,u);)n=Object.getPrototypeOf(n);n\u0026\u0026t(n,...r)}},3434:(e,t,r)=\u003e{\"use strict\";r.d(t,{Jt:()=\u003eo,YM:()=\u003ec});var n=r(7836),i=r(5607);const o=\"nr@original:\".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n=\"\");const a=\"-\"===n.charAt(0);for(let s=0;s\u003ct.length;s++){const c=t[s],u=e[c];d(u)||(e[c]=r(u,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return d(t)?t:(r||(r=\"\"),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty\u0026\u0026Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){u([e],r)}for(var n in e)a.call(e,n)\u0026\u0026(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,d,l;try{a=this,o=[...arguments],d=\"function\"==typeof n?n(o,a):n||{}}catch(t){u([t,\"\",[o,a,s],d],e)}i(r+\"start\",[o,a,s],d,c);try{return l=t.apply(a,o)}catch(e){throw i(r+\"err\",[o,a,e],d,c),e}finally{i(r+\"end\",[o,a,l],d,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){u([t,r,n,i],e)}s=a}}}function u(e,t){t||(t=n.ee);try{t.emit(\"internal-error\",e)}catch(e){}}function d(e){return!(e\u0026\u0026\"function\"==typeof e\u0026\u0026e.apply\u0026\u0026!e[o])}},9300:(e,t,r)=\u003e{\"use strict\";r.d(t,{T:()=\u003en});const n=r(860).K7.ajax},3333:(e,t,r)=\u003e{\"use strict\";r.d(t,{TZ:()=\u003en,Zp:()=\u003ei,mq:()=\u003es,nf:()=\u003ea,qN:()=\u003eo});const n=r(860).K7.genericEvents,i=[\"auxclick\",\"click\",\"copy\",\"keydown\",\"paste\",\"scrollend\"],o=[\"focus\",\"blur\"],a=4,s=1e3},6774:(e,t,r)=\u003e{\"use strict\";r.d(t,{T:()=\u003en});const n=r(860).K7.jserrors},993:(e,t,r)=\u003e{\"use strict\";r.d(t,{ET:()=\u003eo,TZ:()=\u003ea,p_:()=\u003ei});var n=r(860);const i={ERROR:\"ERROR\",WARN:\"WARN\",INFO:\"INFO\",DEBUG:\"DEBUG\",TRACE:\"TRACE\"},o=\"log\",a=n.K7.logging},3785:(e,t,r)=\u003e{\"use strict\";r.d(t,{R:()=\u003ec,b:()=\u003eu});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,[\"API/logging/\".concat(c.toLowerCase(),\"/called\")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function u(e){return\"string\"==typeof e\u0026\u0026Object.values(s.p_).some((t=\u003et===e.toUpperCase().trim()))}},3969:(e,t,r)=\u003e{\"use strict\";r.d(t,{TZ:()=\u003en,XG:()=\u003es,rs:()=\u003ei,xV:()=\u003ea,z_:()=\u003eo});const n=r(860).K7.metrics,i=\"sm\",o=\"cm\",a=\"storeSupportabilityMetrics\",s=\"storeEventMetrics\"},6630:(e,t,r)=\u003e{\"use strict\";r.d(t,{T:()=\u003en});const n=r(860).K7.pageViewEvent},782:(e,t,r)=\u003e{\"use strict\";r.d(t,{T:()=\u003en});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=\u003e{\"use strict\";r.d(t,{BB:()=\u003ed,G4:()=\u003eo,Qb:()=\u003el,TZ:()=\u003ei,Ug:()=\u003ea,_s:()=\u003es,bc:()=\u003eu,yP:()=\u003ec});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:\"recordReplay\",PAUSE:\"pauseReplay\",REPLAY_RUNNING:\"replayRunning\",ERROR_DURING_REPLAY:\"errorDuringReplay\"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},u={RESET:{message:\"Session was reset\",sm:\"Reset\"},IMPORT:{message:\"Recorder failed to import\",sm:\"Import\"},TOO_MANY:{message:\"429: Too Many Requests\",sm:\"Too-Many\"},TOO_BIG:{message:\"Payload was too large\",sm:\"Too-Big\"},CROSS_TAB:{message:\"Session Entity was set to OFF on another tab\",sm:\"Cross-Tab\"},ENTITLEMENTS:{message:\"Session Replay is not allowed and will not be started\",sm:\"Entitlement\"}},d=5e3,l={API:\"api\"}},5270:(e,t,r)=\u003e{\"use strict\";r.d(t,{Aw:()=\u003ec,CT:()=\u003eu,SR:()=\u003es});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO\u0026\u0026(0,o.V)(e)\u0026\u0026!0===(0,i.gD)(e,\"session_trace.enabled\")}function c(e){return!0===(0,i.gD)(e,\"session_replay.preload\")\u0026\u0026s(e)}function u(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=\u003e{\"use strict\";r.d(t,{He:()=\u003ei,Kp:()=\u003es,Lc:()=\u003eu,Rz:()=\u003ed,TZ:()=\u003en,bD:()=\u003eo,d3:()=\u003ea,jx:()=\u003el,uP:()=\u003ec});const n=r(860).K7.sessionTrace,i=\"bstResource\",o=\"resource\",a=\"-start\",s=\"-end\",c=\"fn\"+a,u=\"fn\"+s,d=\"pushState\",l=1e3},3962:(e,t,r)=\u003e{\"use strict\";r.d(t,{AM:()=\u003eo,O2:()=\u003es,Qu:()=\u003ec,TZ:()=\u003ea,ih:()=\u003eu,tC:()=\u003ei});var n=r(860);const i=[\"click\",\"keydown\",\"submit\"],o=\"api\",a=n.K7.softNav,s={INITIAL_PAGE_LOAD:\"\",ROUTE_CHANGE:1,UNSPECIFIED:2},c={INTERACTION:1,AJAX:2,CUSTOM_END:3,CUSTOM_TRACER:4},u={IP:\"in progress\",FIN:\"finished\",CAN:\"cancelled\"}},7378:(e,t,r)=\u003e{\"use strict\";r.d(t,{$p:()=\u003ex,BR:()=\u003eb,Kp:()=\u003eR,L3:()=\u003ey,Lc:()=\u003ec,NC:()=\u003eo,SG:()=\u003ed,TZ:()=\u003ei,U6:()=\u003ep,UT:()=\u003em,d3:()=\u003ew,dT:()=\u003ef,e5:()=\u003eA,gx:()=\u003ev,l9:()=\u003el,oW:()=\u003eh,op:()=\u003eg,rw:()=\u003eu,tH:()=\u003eE,uP:()=\u003es,wW:()=\u003eT,xq:()=\u003ea});var n=r(384);const i=r(860).K7.spa,o=[\"click\",\"submit\",\"keypress\",\"keydown\",\"keyup\",\"change\"],a=999,s=\"fn-start\",c=\"fn-end\",u=\"cb-start\",d=\"api-ixn-\",l=\"remaining\",f=\"interaction\",h=\"spaNode\",p=\"jsonpNode\",g=\"fetch-start\",m=\"fetch-done\",v=\"fetch-body-\",b=\"jsonp-end\",y=(0,n.dV)().o.ST,w=\"-start\",R=\"-end\",x=\"-body\",T=\"cb\"+R,A=\"jsTime\",E=\"fetch\"},4234:(e,t,r)=\u003e{\"use strict\";r.d(t,{W:()=\u003eo});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=\u003e{\"use strict\";r.d(t,{V:()=\u003eo});var n=r(9417),i=r(6154);const o=e=\u003ei.RI\u0026\u0026!0===(0,n.gD)(e,\"privacy.cookies_enabled\")},425:(e,t,r)=\u003e{\"use strict\";r.d(t,{j:()=\u003ej});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),u=r(5289),d=r(6154),l=r(944),f=r(3969),h=r(384),p=r(6344);const g=[\"setErrorHandler\",\"finished\",\"addToTrace\",\"addRelease\",\"addPageAction\",\"setCurrentRouteName\",\"setPageViewName\",\"setCustomAttribute\",\"interaction\",\"noticeError\",\"setUserId\",\"setApplicationVersion\",\"start\",p.G4.RECORD,p.G4.PAUSE,\"log\",\"wrapLogger\"],m=[\"setErrorHandler\",\"finished\",\"addToTrace\",\"addRelease\"];var v=r(1863),b=r(2614),y=r(993),w=r(3785),R=r(2646),x=r(3434);function T(e,t,r,n){if(\"object\"!=typeof t||!t||\"string\"!=typeof r||!r||\"function\"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get(\"logger\")}(e),o=(0,x.YM)(i),a=new R.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],\"wrap-logger-\",a),i}function A(){const e=(0,h.pV)();g.forEach((t=\u003e{e[t]=(...r)=\u003efunction(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=\u003e{e\u0026\u0026e.api?e.exposed\u0026\u0026e.api[t]\u0026\u0026n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length\u003e1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),N=r(5603),O=r(5284);const _=e=\u003e{const t=e.startsWith(\"http\");e+=\"/\",r.p=t?e:\"https://\"+e};let I=!1;function j(e,t={},g,R){let{init:x,info:j,loader_config:P,runtime:C={},exposed:k=!0}=t;C.loaderType=g;const L=(0,h.pV)();j||(x=L.init,j=L.info,P=L.loader_config),(0,S.xN)(e.agentIdentifier,x||{}),(0,N.a)(e.agentIdentifier,P||{}),j.jsAttributes??={},d.bv\u0026\u0026(j.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,j);const H=(0,S.D0)(e.agentIdentifier),D=[j.beacon,j.errorBeacon];I||(H.proxy.assets\u0026\u0026(_(H.proxy.assets),D.push(H.proxy.assets)),H.proxy.beacon\u0026\u0026D.push(H.proxy.beacon),A(),(0,h.US)(\"activatedFeatures\",O.B),e.runSoftNavOverSpa\u0026\u0026=!0===H.soft_navigations.enabled\u0026\u0026H.feature_flags.includes(\"soft_nav\")),C.denyList=[...H.ajax.deny_list||[],...H.ajax.block_internal?D:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api\u0026\u0026(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,\"api\");const g={};var R=s.ee.get(e),x=R.get(\"tracer\");E[e]=b.g.OFF,R.on(p.G4.REPLAY_RUNNING,(t=\u003e{E[e]=t}));var A=\"api-\",S=A+\"ixn-\";function N(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?\"session\":void 0)(t,r)}function O(){}g.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,[\"API/log/called\"],void 0,n.K7.metrics,R),(0,w.R)(R,e,t,r)},g.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=\u003e{(0,a.p)(f.xV,[\"API/wrapLogger/called\"],void 0,n.K7.metrics,R),T(R,e,t,{customAttributes:r,level:i})},m.forEach((e=\u003e{g[e]=I(A,e,!0,\"api\")})),g.addPageAction=I(A,\"addPageAction\",!0,n.K7.genericEvents),g.setPageViewName=function(t,r){if(\"string\"==typeof t)return\"/\"!==t.charAt(0)\u0026\u0026(t=\"/\"+t),(0,o.f)(e).customTransaction=(r||\"http://custom.transaction\")+t,I(A,\"setPageViewName\",!0)()},g.setCustomAttribute=function(e,t,r=!1){if(\"string\"==typeof e){if([\"string\",\"number\",\"boolean\"].includes(typeof t)||null===t)return N(e,t,\"setCustomAttribute\",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},g.setUserId=function(e){if(\"string\"==typeof e||null===e)return N(\"enduser.id\",e,\"setUserId\",!0);(0,l.R)(41,typeof e)},g.setApplicationVersion=function(e){if(\"string\"==typeof e||null===e)return N(\"application.version\",e,\"setApplicationVersion\",!1);(0,l.R)(42,typeof e)},g.start=()=\u003e{try{(0,a.p)(f.xV,[\"API/start/called\"],void 0,n.K7.metrics,R),R.emit(\"manual-start-all\")}catch(e){(0,l.R)(23,e)}},g[p.G4.RECORD]=function(){(0,a.p)(f.xV,[\"API/recordReplay/called\"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.RECORD,[],void 0,n.K7.sessionReplay,R)},g[p.G4.PAUSE]=function(){(0,a.p)(f.xV,[\"API/pauseReplay/called\"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.PAUSE,[],void 0,n.K7.sessionReplay,R)},g.interaction=function(e){return(new O).get(\"object\"==typeof e?e:{})};const _=O.prototype={createTracer:function(e,t){var r={},i=this,o=\"function\"==typeof t;return(0,a.p)(f.xV,[\"API/createTracer/called\"],void 0,n.K7.metrics,R),h||(0,a.p)(S+\"tracer\",[(0,v.t)(),e,r],i,n.K7.spa,R),function(){if(x.emit((o?\"\":\"no-\")+\"fn-start\",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t=\"string\"==typeof e?new Error(e):e;throw x.emit(\"fn-err\",[arguments,this,t],r),t}finally{x.emit(\"fn-end\",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,[\"API/\"+t+\"/called\"],void 0,n.K7.metrics,R),i\u0026\u0026(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,R),r?void 0:this}}function j(){r.e(478).then(r.bind(r,8778)).then((({setAPI:t})=\u003e{t(e),(0,c.Ze)(e,\"api\")})).catch((e=\u003e{(0,l.R)(27,e),R.abort()}))}return[\"actionText\",\"setName\",\"setAttribute\",\"save\",\"ignore\",\"onEnd\",\"getContext\",\"end\",\"get\"].forEach((e=\u003e{_[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),g.setCurrentRouteName=h?I(S,\"routeName\",void 0,n.K7.softNav):I(A,\"routeName\",!0,n.K7.spa),g.noticeError=function(t,r){\"string\"==typeof t\u0026\u0026(t=new Error(t)),(0,a.p)(f.xV,[\"API/noticeError/called\"],void 0,n.K7.metrics,R),(0,a.p)(\"err\",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,R)},d.RI?(0,u.GG)((()=\u003ej()),!0):j(),g}(e.agentIdentifier,R,e.runSoftNavOverSpa)),void 0===e.exposed\u0026\u0026(e.exposed=k),I=!0}},8374:(e,t,r)=\u003e{r.nc=(()=\u003e{try{return document?.currentScript?.nonce}catch(e){}return\"\"})()},860:(e,t,r)=\u003e{\"use strict\";r.d(t,{$J:()=\u003eo,K7:()=\u003en,P3:()=\u003ei});const n={ajax:\"ajax\",genericEvents:\"generic_events\",jserrors:\"jserrors\",logging:\"logging\",metrics:\"metrics\",pageAction:\"page_action\",pageViewEvent:\"page_view_event\",pageViewTiming:\"page_view_timing\",sessionReplay:\"session_replay\",sessionTrace:\"session_trace\",softNav:\"soft_navigations\",spa:\"spa\"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:\"events\",[n.ajax]:\"events\",[n.spa]:\"events\",[n.softNav]:\"events\",[n.metrics]:\"jserrors\",[n.jserrors]:\"jserrors\",[n.sessionTrace]:\"browser/blobs\",[n.sessionReplay]:\"browser/blobs\",[n.logging]:\"browser/logs\",[n.genericEvents]:\"ins\"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=\u003e{for(var r in t)i.o(t,r)\u0026\u0026!i.o(e,r)\u0026\u0026Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=\u003ePromise.all(Object.keys(i.f).reduce(((t,r)=\u003e(i.f[r](e,t),t)),[])),i.u=e=\u003e({212:\"nr-spa-compressor\",249:\"nr-spa-recorder\",478:\"nr-spa\"}[e]+\"-1.274.0.min.js\"),i.o=(e,t)=\u003eObject.prototype.hasOwnProperty.call(e,t),e={},t=\"NRBA-1.274.0.PROD:\",i.l=(r,n,o,a)=\u003e{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var u=document.getElementsByTagName(\"script\"),d=0;d\u003cu.length;d++){var l=u[d];if(l.getAttribute(\"src\")==r||l.getAttribute(\"data-webpack\")==t+o){s=l;break}}if(!s){c=!0;var f={478:\"sha512-1vUqEfJPB8Pihje9mv5CfYgkitO1FWcS+UQb84DbXqP8oYctRv4/lzl/MzNLPlRhcY1WVDBGL20I8vm6s2VV7g==\",249:\"sha512-Y/BeZAh6VSTmUtUNmS5XdyKxL92s30Fyyj8xVW76HSPxcKItL4+x2+kGMZc8pMJnUpZDz1L4eftZQAJh3D8NnA==\",212:\"sha512-Gn2tQ3qog5Yhrx/gRutkSTYPp+7nkKFt4/mIXg99LxcNpMDAYJZDBYmAACdoHNM86+iq1F3cBcQotFNzjIX8bw==\"};(s=document.createElement(\"script\")).charset=\"utf-8\",s.timeout=120,i.nc\u0026\u0026s.setAttribute(\"nonce\",i.nc),s.setAttribute(\"data-webpack\",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+\"/\")\u0026\u0026(s.crossOrigin=\"anonymous\"),f[a]\u0026\u0026(s.integrity=f[a])}e[r]=[n];var h=(t,n)=\u003e{s.onerror=s.onload=null,clearTimeout(p);var i=e[r];if(delete e[r],s.parentNode\u0026\u0026s.parentNode.removeChild(s),i\u0026\u0026i.forEach((e=\u003ee(n))),t)return t(n)},p=setTimeout(h.bind(null,void 0,{type:\"timeout\",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c\u0026\u0026document.head.appendChild(s)}},i.r=e=\u003e{\"undefined\"!=typeof Symbol\u0026\u0026Symbol.toStringTag\u0026\u0026Object.defineProperty(e,Symbol.toStringTag,{value:\"Module\"}),Object.defineProperty(e,\"__esModule\",{value:!0})},i.p=\"https://js-agent.newrelic.com/\",(()=\u003e{var e={38:0,788:0};i.f.j=(t,r)=\u003e{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=\u003en=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=\u003e{if(i.o(e,t)\u0026\u0026(0!==(n=e[t])\u0026\u0026(e[t]=void 0),n)){var o=r\u0026\u0026(\"load\"===r.type?\"missing\":r.type),a=r\u0026\u0026r.target\u0026\u0026r.target.src;s.message=\"Loading chunk \"+t+\" failed.\\n(\"+o+\": \"+a+\")\",s.name=\"ChunkLoadError\",s.type=o,s.request=a,n[1](s)}}),\"chunk-\"+t,t)}};var t=(t,r)=\u003e{var n,o,[a,s,c]=r,u=0;if(a.some((t=\u003e0!==e[t]))){for(n in s)i.o(s,n)\u0026\u0026(i.m[n]=s[n]);if(c)c(i)}for(t\u0026\u0026t(r);u\u003ca.length;u++)o=a[u],i.o(e,o)\u0026\u0026e[o]\u0026\u0026e[o][0](),e[o]=0},r=self[\"webpackChunk:NRBA-1.274.0.PROD\"]=self[\"webpackChunk:NRBA-1.274.0.PROD\"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=\u003e{\"use strict\";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if(\"function\"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e(\"addPageAction\",e,t)}setPageViewName(e,t){return this.#e(\"setPageViewName\",e,t)}setCustomAttribute(e,t,r){return this.#e(\"setCustomAttribute\",e,t,r)}noticeError(e,t){return this.#e(\"noticeError\",e,t)}setUserId(e){return this.#e(\"setUserId\",e)}setApplicationVersion(e){return this.#e(\"setApplicationVersion\",e)}setErrorHandler(e){return this.#e(\"setErrorHandler\",e)}addRelease(e,t){return this.#e(\"addRelease\",e,t)}log(e,t){return this.#e(\"log\",e,t)}}class o extends n{#e(t,...r){if(\"function\"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e(\"start\")}finished(e){return this.#e(\"finished\",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e(\"addToTrace\",e)}setCurrentRouteName(e){return this.#e(\"setCurrentRouteName\",e)}interaction(){return this.#e(\"interaction\")}wrapLogger(e,t,r){return this.#e(\"wrapLogger\",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function u(e){const t={};return c.forEach((r=\u003e{t[r]=function(e,t){return!0===(0,s.gD)(t,\"\".concat(e,\".enabled\"))}(r,e)})),t}var d=i(425);var l=i(1687),f=i(4234),h=i(5289),p=i(6154),g=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart\u0026\u0026(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on(\"manual-start-all\",(0,v.J)((()=\u003e{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=\u003e{n=e}));const o=async()=\u003e{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(478).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit(\"internal-error\",[t]),this.featureName===a.K7.sessionReplay\u0026\u0026this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(478).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(478).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,\"aggregate\");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee\u0026\u0026this.ee.abort()}};p.RI?(0,h.GG)((()=\u003eo()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,g.SR)(this.agentIdentifier)\u0026\u0026!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class w extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var R=i(384);var x=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class N extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),p.RI\u0026\u0026((0,T.u)((()=\u003e(0,x.p)(\"docHidden\",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)(\"pagehide\",(()=\u003e(0,x.p)(\"winPagehide\",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class _ extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),j=i(3304);class P{constructor(e,t,r,n,i){this.name=\"UncaughtError\",this.message=\"string\"==typeof e?e:(0,j.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return H(e)?e:new P(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t=\"Unhandled Promise Rejection\";if(!e?.reason)return;if(H(e.reason))try{return e.reason.message=t+\": \"+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+\": \"+r?.message,r}function L(e){if(e.error instanceof SyntaxError\u0026\u0026!/:\\d+$/.test(e.error.stack?.trim())){const t=new P(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return H(e.error)?e.error:C(e)}function H(e){return e instanceof Error\u0026\u0026!!e.stack}class D extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on(\"internal-error\",(e=\u003e{this.abortHandler\u0026\u0026(0,x.p)(\"ierr\",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=\u003e{this.#r=e})),p.gm.addEventListener(\"unhandledrejection\",(e=\u003e{this.abortHandler\u0026\u0026(0,x.p)(\"err\",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),p.gm.addEventListener(\"error\",(e=\u003e{this.abortHandler\u0026\u0026(0,x.p)(\"err\",[L(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var M=i(8990);let K=1;const U=\"nr@id\";function V(e){const t=typeof e;return!e||\"object\"!==t\u0026\u0026\"function\"!==t?-1:e===p.gm?0:(0,M.I)(e,U,(function(){return K++}))}function G(e){if(\"string\"==typeof e\u0026\u0026e.length)return e.length;if(\"object\"==typeof e){if(\"undefined\"!=typeof ArrayBuffer\u0026\u0026e instanceof ArrayBuffer\u0026\u0026e.byteLength)return e.byteLength;if(\"undefined\"!=typeof Blob\u0026\u0026e instanceof Blob\u0026\u0026e.size)return e.size;if(!(\"undefined\"!=typeof FormData\u0026\u0026e instanceof FormData))try{return(0,j.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=[\"open\",\"send\"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get(\"xhr\")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=p.gm.XMLHttpRequest,a=p.gm.MutationObserver,s=p.gm.Promise,c=p.gm.setInterval,u=\"readystatechange\",d=[\"onload\",\"onerror\",\"onabort\",\"onloadstart\",\"onloadend\",\"onprogress\",\"ontimeout\"],l=[],f=p.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit(\"new-xhr\",[r],a),r.addEventListener(u,(s=a,function(){var e=this;e.readyState\u003e3\u0026\u0026!s.resolved\u0026\u0026(s.resolved=!0,n.emit(\"xhr-resolved\",[],e)),i.inPlace(e,d,\"fn-\",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit(\"internal-error\",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,[\"onreadystatechange\"],\"fn-\",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,\"-xhr-\",y),n.on(\"send-xhr-start\",(function(e,t){h(e,t),function(e){l.push(e),a\u0026\u0026(g?g.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on(\"open-xhr-start\",h),a){var g=s\u0026\u0026s.resolve();if(!c\u0026\u0026!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on(\"fn-end\",(function(e){e[0]\u0026\u0026e[0].type===u||b()}));function b(){for(var e=0;e\u003cl.length;e++)h(0,l[e]);l.length\u0026\u0026(l=[])}function y(e,t){return t}return n}var Y=\"fetch-\",X=Y+\"body-\",J=[\"arrayBuffer\",\"blob\",\"json\",\"text\",\"formData\"],Q=p.gm.Request,ee=p.gm.Response,te=\"prototype\";const re={};function ne(e){const t=function(e){return(e||B.ee).get(\"fetch\")}(e);if(!(Q\u0026\u0026ee\u0026\u0026p.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];\"function\"==typeof i\u0026\u0026(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+\"before-start\",[r],o),o[B.P]\u0026\u0026o[B.P].dt\u0026\u0026(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+\"start\",[r,e],a),a.then((function(e){return t.emit(n+\"end\",[null,e],a),e}),(function(e){throw t.emit(n+\"end\",[e],a),e}))})}return re[t.debugId]=1,J.forEach((e=\u003e{r(Q[te],e,X),r(ee[te],e,X)})),r(p.gm,\"fetch\",Y),t.on(Y+\"end\",(function(e,r){var n=this;if(r){var i=r.headers.get(\"content-length\");null!==i\u0026\u0026(n.rxSize=i),t.emit(Y+\"done\",[null,r],n)}else t.emit(Y+\"done\",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||\"\").toString()||null,i=(t.agentID||\"\").toString()||null,o=(t.trustKey||\"\").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),u={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)\u0026\u0026this.useTraceContextHeadersForCors())\u0026\u0026(u.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),u.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin\u0026\u0026!this.excludeNewrelicHeader()||!e.sameOrigin\u0026\u0026this.isAllowedOrigin(e)\u0026\u0026this.useNewrelicHeaderForCors())\u0026\u0026(u.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),u}generateTraceContextParentHeader(e,t){return\"00-\"+t+\"-\"+e+\"-01\"}generateTraceContextStateHeader(e,t,r,n,i){return i+\"@nr=0-1-\"+r+\"-\"+n+\"-\"+e+\"----\"+t}generateTraceHeader(e,t,r,n,i,o){if(!(\"function\"==typeof p.gm?.btoa))return null;var a={v:[0,1],d:{ty:\"Browser\",ac:n,ap:i,id:e,tr:t,ti:r}};return o\u0026\u0026n!==o\u0026\u0026(a.d.tk=o),btoa((0,j.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()\u0026\u0026this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,\"distributed_tracing\")\u0026\u0026(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n\u003cr.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname\u0026\u0026e.protocol===i.protocol\u0026\u0026e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,\"distributed_tracing\");return!!e\u0026\u0026!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,\"distributed_tracing\");return!!e\u0026\u0026!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,\"distributed_tracing\");return!!e\u0026\u0026!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,\"distributed_tracing\");return!!e\u0026\u0026!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),ue=[\"load\",\"error\",\"abort\",\"timeout\"],de=ue.length,le=(0,R.dV)().o.REQ,fe=(0,R.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=\u003e(0,x.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:\"xhr\",fetch:\"fetch\",beacon:\"beacon\"};p.gm?.performance?.getEntriesByType(\"resource\").forEach((t=\u003e{if(t.initiatorType in e\u0026\u00260!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};pe(r,t.name),this.handler(\"xhr\",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=R,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener(\"load\",(function(r){T(t,e)}),(0,A.jT)(!1)),p.lR||e.addEventListener(\"progress\",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},pe(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid\u0026\u0026this.sameOrigin\u0026\u0026r.setRequestHeader(\"X-NewRelic-ID\",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader\u0026\u0026(r.setRequestHeader(\"newrelic\",i.newrelicHeader),o=!0),i.traceContextParentHeader\u0026\u0026(r.setRequestHeader(\"traceparent\",i.traceContextParentHeader),i.traceContextStateHeader\u0026\u0026r.setRequestHeader(\"tracestate\",i.traceContextStateHeader),o=!0),o\u0026\u0026(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n\u0026\u0026i){var a=G(i);a\u0026\u0026(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{\"abort\"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),(\"load\"!==e.type||o.called===o.totalCbs\u0026\u0026(o.onloadCalled||\"function\"!=typeof r.onload)\u0026\u0026\"function\"==typeof o.end)\u0026\u0026o.end(r)}catch(e){try{t.emit(\"internal-error\",[e])}catch(e){}}};for(var s=0;s\u003cde;s++)r.addEventListener(ue[s],this.listener,(0,A.jT)(!1))}function u(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled\u0026\u0026\"function\"==typeof r.onload||\"function\"!=typeof this.end||this.end(r)}function d(e,t){var r=\"\"+V(e)+!!t;this.xhrGuids\u0026\u0026!this.xhrGuids[r]\u0026\u0026(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=\"\"+V(e)+!!t;this.xhrGuids\u0026\u0026this.xhrGuids[r]\u0026\u0026(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe\u0026\u0026\"load\"===e[0]\u0026\u0026t.emit(\"xhr-load-added\",[e[1],e[2]],r)}function g(e,r){r instanceof fe\u0026\u0026\"load\"===e[0]\u0026\u0026t.emit(\"xhr-load-removed\",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe\u0026\u0026(\"onload\"===r\u0026\u0026(this.onload=!0),(\"load\"===(e[0]\u0026\u0026e[0].type)||this.onload)\u0026\u0026(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart\u0026\u0026t.emit(\"xhr-cb-time\",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if(\"string\"==typeof e[0]?0===(t=e[0]).length\u0026\u0026p.RI\u0026\u0026(t=\"\"+p.gm.location.href):e[0]\u0026\u0026e[0].url?t=e[0].url:p.gm?.URL\u0026\u0026e[0]\u0026\u0026e[0]instanceof URL?t=e[0].href:\"function\"==typeof e[0].toString\u0026\u0026(t=e[0].toString()),\"string\"==typeof t\u0026\u00260!==t.length){t\u0026\u0026(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i\u0026\u0026(i.newrelicHeader||i.traceContextParentHeader))if(e[0]\u0026\u0026e[0].headers)s(e[0].headers,i)\u0026\u0026(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)\u0026\u0026(this.dt=i),e.length\u003e1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader\u0026\u0026(e.set(\"newrelic\",t.newrelicHeader),r=!0),t.traceContextParentHeader\u0026\u0026(e.set(\"traceparent\",t.traceContextParentHeader),t.traceContextStateHeader\u0026\u0026e.set(\"tracestate\",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length\u003e=1\u0026\u0026(this.target=e[0]),e.length\u003e=2\u0026\u0026(this.opts=e[1]);var r,n=this.opts||{},i=this.target;\"string\"==typeof i?r=i:\"object\"==typeof i\u0026\u0026i instanceof le?r=i.url:p.gm?.URL\u0026\u0026\"object\"==typeof i\u0026\u0026i instanceof URL\u0026\u0026(r=i.href),pe(this,r);var o=(\"\"+(i\u0026\u0026i instanceof le\u0026\u0026i.method||n.method||\"GET\")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function w(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,\"string\"==typeof this.rxSize\u0026\u0026this.rxSize.length\u003e0\u0026\u0026(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r(\"xhr\",[this.params,i,this.startTime,this.endTime,\"fetch\"],this,a.K7.ajax)}function R(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t\u003cde;t++)e.removeEventListener(ue[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status\u0026\u0026(t.status=0):T(this,e),n.cbTime=this.cbTime,r(\"xhr\",[t,n,this.startTime,this.endTime,\"xhr\"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return\"json\"===r\u0026\u0026null!==t?t:\"arraybuffer\"===r||\"blob\"===r||\"json\"===r?G(e.response):\"text\"===r||\"\"===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n\u0026\u0026(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader(\"X-NewRelic-App-Data\");i\u0026\u0026((0,x.p)(O.rs,[\"Ajax/CrossApplicationTracing/Header/Seen\"],void 0,a.K7.metrics,t),e.params.cat=i.split(\", \").pop())}e.loadCaptureCalled=!0}t.on(\"new-xhr\",i),t.on(\"open-xhr-start\",o),t.on(\"open-xhr-end\",s),t.on(\"send-xhr-start\",c),t.on(\"xhr-cb-time\",u),t.on(\"xhr-load-added\",d),t.on(\"xhr-load-removed\",l),t.on(\"xhr-resolved\",f),t.on(\"addEventListener-end\",h),t.on(\"removeEventListener-end\",g),t.on(\"fn-end\",v),t.on(\"fetch-before-start\",b),t.on(\"fetch-start\",y),t.on(\"fn-start\",m),t.on(\"fetch-done\",w)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function pe(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+\":\"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const ge={},me=[\"pushState\",\"replaceState\"];function ve(e){const t=function(e){return(e||B.ee).get(\"history\")}(e);return!p.RI||ge[t.debugId]++||(ge[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,\"-\")),t}var be=i(3738);const{He:ye,bD:we,d3:Re,Kp:xe,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class Ne extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,x.p)(\"bst\",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+Re,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+xe,(function(e){(0,x.p)(\"bstHist\",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=\u003e{const t=e.getEntries();(0,x.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:we,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class _e extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem(\"\".concat(Oe.H3,\"_\").concat(Oe.uh)))}catch(e){}(0,g.SR)(e.agentIdentifier)\u0026\u0026this.ee.on(t.G4.RECORD,(()=\u003ethis.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on(\"err\",(e=\u003e{this.replayRunning\u0026\u0026(this.errorNoticed=!0,(0,x.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=\u003e{this.replayRunning=e}))}#s(e){return e\u0026\u0026(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,g.Aw)(this.agentIdentifier)}#u=!1;async#c(e){if(!this.#u){this.#u=!0;try{const{Recorder:t}=await Promise.all([i.e(478),i.e(249)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL\u0026\u0026this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder\u0026\u0026this.recorder.parent.mode!==Oe.g.FULL\u0026\u0026(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3962);class je extends b{static featureName=Ie.TZ;constructor(e,t=!0){if(super(e,Ie.TZ,t),!p.RI||!(0,R.dV)().o.MO)return;const r=ve(this.ee);Ie.tC.forEach((e=\u003e{(0,A.sp)(e,(e=\u003e{a(e)}),!0)}));const n=()=\u003e(0,x.p)(\"newURL\",[(0,S.t)(),\"\"+window.location],void 0,this.featureName,this.ee);r.on(\"pushState-end\",n),r.on(\"replaceState-end\",n);try{this.removeOnAbort=new AbortController}catch(e){}(0,A.sp)(\"popstate\",(e=\u003e(0,x.p)(\"newURL\",[e.timeStamp,\"\"+window.location],void 0,this.featureName,this.ee)),!0,this.removeOnAbort?.signal);let i=!1;const o=new((0,R.dV)().o.MO)(((e,t)=\u003e{i||(i=!0,requestAnimationFrame((()=\u003e{(0,x.p)(\"newDom\",[(0,S.t)()],void 0,this.featureName,this.ee),i=!1})))})),a=(0,v.s)((e=\u003e{(0,x.p)(\"newUIEvent\",[e],void 0,this.featureName,this.ee),o.observe(document.body,{attributes:!0,childList:!0,subtree:!0,characterData:!0})}),100,{leading:!0});this.abortHandler=function(){this.removeOnAbort?.abort(),o.disconnect(),this.abortHandler=void 0},this.importAggregator(e,{domObserver:o})}}var Pe=i(7378);const Ce={},ke=[\"appendChild\",\"insertBefore\",\"replaceChild\"];function Le(e){const t=function(e){return(e||B.ee).get(\"jsonp\")}(e);if(!p.RI||Ce[t.debugId])return t;Ce[t.debugId]=!0;var r=(0,W.YM)(t),n=/[?\u0026](?:callback|cb)=([^\u0026#]+)/,i=/(.*)\\.([^.]+)/,o=/^(\\w+)(\\.|$)(.*)$/;function a(e,t){if(!e)return t;const r=e.match(o),n=r[1];return a(r[3],t[n])}return r.inPlace(Node.prototype,ke,\"dom-\"),t.on(\"dom-start\",(function(e){!function(e){if(!e||\"string\"!=typeof e.nodeName||\"script\"!==e.nodeName.toLowerCase())return;if(\"function\"!=typeof e.addEventListener)return;var o=(s=e.src,c=s.match(n),c?c[1]:null);var s,c;if(!o)return;var u=function(e){var t=e.match(i);if(t\u0026\u0026t.length\u003e=3)return{key:t[2],parent:a(t[1],window)};return{key:e,parent:window}}(o);if(\"function\"!=typeof u.parent[u.key])return;var d={};function l(){t.emit(\"jsonp-end\",[],d),e.removeEventListener(\"load\",l,(0,A.jT)(!1)),e.removeEventListener(\"error\",f,(0,A.jT)(!1))}function f(){t.emit(\"jsonp-error\",[],d),t.emit(\"jsonp-end\",[],d),e.removeEventListener(\"load\",l,(0,A.jT)(!1)),e.removeEventListener(\"error\",f,(0,A.jT)(!1))}r.inPlace(u.parent,[u.key],\"cb-\",d),e.addEventListener(\"load\",l,(0,A.jT)(!1)),e.addEventListener(\"error\",f,(0,A.jT)(!1)),t.emit(\"new-jsonp\",[e.src],d)}(e[0])})),t}const He={};function De(e){const t=function(e){return(e||B.ee).get(\"promise\")}(e);if(He[t.debugId])return t;He[t.debugId]=!0;var r=t.context,n=(0,W.YM)(t),i=p.gm.Promise;return i\u0026\u0026function(){function e(r){var o=t.context(),a=n(r,\"executor-\",o,null,!1);const s=Reflect.construct(i,[a],e);return t.context(s).getCtx=function(){return o},s}p.gm.Promise=e,Object.defineProperty(e,\"name\",{value:\"Promise\"}),e.toString=function(){return i.toString()},Object.setPrototypeOf(e,i),[\"all\",\"race\"].forEach((function(r){const n=i[r];e[r]=function(e){let i=!1;[...e||[]].forEach((e=\u003e{this.resolve(e).then(a(\"all\"===r),a(!1))}));const o=n.apply(this,arguments);return o;function a(e){return function(){t.emit(\"propagate\",[null,!i],o,!1,!1),i=i||!e}}}})),[\"resolve\",\"reject\"].forEach((function(r){const n=i[r];e[r]=function(e){const r=n.apply(this,arguments);return e!==r\u0026\u0026t.emit(\"propagate\",[e,!0],r,!1,!1),r}})),e.prototype=i.prototype;const o=i.prototype.then;i.prototype.then=function(...e){var i=this,a=r(i);a.promise=i,e[0]=n(e[0],\"cb-\",a,null,!1),e[1]=n(e[1],\"cb-\",a,null,!1);const s=o.apply(this,e);return a.nextPromise=s,t.emit(\"propagate\",[i,!0],s,!1,!1),s},i.prototype.then[W.Jt]=o,t.on(\"executor-start\",(function(e){e[0]=n(e[0],\"resolve-\",this,null,!1),e[1]=n(e[1],\"resolve-\",this,null,!1)})),t.on(\"executor-err\",(function(e,t,r){e[1](r)})),t.on(\"cb-end\",(function(e,r,n){t.emit(\"propagate\",[n,!0],this.nextPromise,!1,!1)})),t.on(\"propagate\",(function(e,r,n){this.getCtx\u0026\u0026!r||(this.getCtx=function(){if(e instanceof Promise)var r=t.context(e);return r\u0026\u0026r.getCtx?r.getCtx():this})}))}(),t}const Me={},Ke=\"setTimeout\",Ue=\"setInterval\",Ve=\"clearTimeout\",Ge=\"-start\",Fe=[Ke,\"setImmediate\",Ue,Ve,\"clearImmediate\"];function Be(e){const t=function(e){return(e||B.ee).get(\"timer\")}(e);if(Me[t.debugId]++)return t;Me[t.debugId]=1;var r=(0,W.YM)(t);return r.inPlace(p.gm,Fe.slice(0,2),Ke+\"-\"),r.inPlace(p.gm,Fe.slice(2,3),Ue+\"-\"),r.inPlace(p.gm,Fe.slice(3),Ve+\"-\"),t.on(Ue+Ge,(function(e,t,n){e[0]=r(e[0],\"fn-\",null,n)})),t.on(Ke+Ge,(function(e,t,n){this.method=n,this.timerDuration=isNaN(e[1])?0:+e[1],e[0]=r(e[0],\"fn-\",this,n)})),t}const We={};function ze(e){const t=function(e){return(e||B.ee).get(\"mutation\")}(e);if(!p.RI||We[t.debugId])return t;We[t.debugId]=!0;var r=(0,W.YM)(t),n=p.gm.MutationObserver;return n\u0026\u0026(window.MutationObserver=function(e){return this instanceof n?new n(r(e,\"fn-\")):n.apply(this,arguments)},MutationObserver.prototype=n.prototype),t}const{TZ:qe,d3:Ze,Kp:Ye,$p:Xe,wW:Je,e5:Qe,tH:$e,uP:et,rw:tt,Lc:rt}=Pe;class nt extends b{static featureName=qe;constructor(e,t=!0){if(super(e,qe,t),!p.RI)return;try{this.removeOnAbort=new AbortController}catch(e){}let r,n=0;const i=this.ee.get(\"tracer\"),o=Le(this.ee),a=De(this.ee),s=Be(this.ee),c=Z(this.ee),u=this.ee.get(\"events\"),d=ne(this.ee),l=ve(this.ee),f=ze(this.ee);function h(e,t){l.emit(\"newURL\",[\"\"+window.location,t])}function g(){n++,r=window.location.hash,this[et]=(0,S.t)()}function m(){n--,window.location.hash!==r\u0026\u0026h(0,!0);var e=(0,S.t)();this[Qe]=~~this[Qe]+e-this[et],this[rt]=e}function v(e,t){e.on(t,(function(){this[t]=(0,S.t)()}))}this.ee.on(et,g),a.on(tt,g),o.on(tt,g),this.ee.on(rt,m),a.on(Je,m),o.on(Je,m),this.ee.on(\"fn-err\",((...t)=\u003e{t[2]?.__newrelic?.[e.agentIdentifier]||(0,x.p)(\"function-err\",[...t],void 0,this.featureName,this.ee)})),this.ee.buffer([et,rt,\"xhr-resolved\"],this.featureName),u.buffer([et],this.featureName),s.buffer([\"setTimeout\"+Ye,\"clearTimeout\"+Ze,et],this.featureName),c.buffer([et,\"new-xhr\",\"send-xhr\"+Ze],this.featureName),d.buffer([$e+Ze,$e+\"-done\",$e+Xe+Ze,$e+Xe+Ye],this.featureName),l.buffer([\"newURL\"],this.featureName),f.buffer([et],this.featureName),a.buffer([\"propagate\",tt,Je,\"executor-err\",\"resolve\"+Ze],this.featureName),i.buffer([et,\"no-\"+et],this.featureName),o.buffer([\"new-jsonp\",\"cb-start\",\"jsonp-error\",\"jsonp-end\"],this.featureName),v(d,$e+Ze),v(d,$e+\"-done\"),v(o,\"new-jsonp\"),v(o,\"jsonp-end\"),v(o,\"cb-start\"),l.on(\"pushState-end\",h),l.on(\"replaceState-end\",h),window.addEventListener(\"hashchange\",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener(\"load\",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener(\"popstate\",(function(){h(0,n\u003e1)}),(0,A.jT)(!0,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var it=i(3333);class ot extends b{static featureName=it.TZ;constructor(e,t=!0){super(e,it.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];p.RI\u0026\u0026e.init.user_actions.enabled\u0026\u0026(it.Zp.forEach((e=\u003e(0,A.sp)(e,(e=\u003e(0,x.p)(\"ua\",[e],void 0,this.featureName,this.ee)),!0))),it.qN.forEach((e=\u003e(0,A.sp)(e,(e=\u003e(0,x.p)(\"ua\",[e],void 0,this.featureName,this.ee)))))),r.some((e=\u003ee))?this.importAggregator(e):this.deregisterDrain()}}var at=i(993),st=i(3785);class ct extends b{static featureName=at.TZ;constructor(e,t=!0){super(e,at.TZ,t);const r=this.ee;this.ee.on(\"wrap-logger-end\",(function([e]){const{level:t,customAttributes:n}=this;(0,st.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),p.gm?(this.features={},(0,R.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(w),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=\u003ee.featureName===a.K7.softNav)),(0,d.j)(this,t,t.loaderType||\"agent\"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=u(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=\u003ea.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=\u003e{if(!t[r.featureName]\u0026\u0026r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa\u0026\u0026r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa\u0026\u0026r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=\u003e!(e in this.features)));n.length\u003e0\u0026\u0026(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,R.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[he,w,N,Ne,_e,_,D,ot,ct,je,nt],loaderType:\"spa\"})})()})();\n","testAutomationFlags":{"disableAds":false,"disableIirisAuth":false,"disableWelcomeAd":false,"disableBigskyAd":false,"disableIirisRecommend":false,"disableDcts":false,"disableWeatherWidget":false,"disableCashGrainWidget":false,"disableCommoditiesWidget":false,"disableCaptcha":false,"disableCookieBanner":false,"overrideBrandStyling":"","overrideThemeStyling":""},"configState":{"font":{"primary":{"name":"Open Sans","url":"https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,500;0,600;0,700;0,800;1,300;1,400;1,500;1,600;1,700;1,800\u0026display=swap"},"secondary":{"name":"Open Sans","url":"https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,500;0,600;0,700;0,800;1,300;1,400;1,500;1,600;1,700;1,800\u0026display=swap"}},"theme":"theme1","uiBrand":"bioprocessinternational","isMarketsDivision":false,"image":{"brand":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3e63117d402385a5/6540f7a0c9a677040ac88e06/placeholder.svg","contributor":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/bltf573a3db8aace5de/653a7dfd8d60da0407d884d2/theme1_placeholder_avatar.png"},"media":{"brightcoveAccountId":""},"newsletterSignupPromo":{"unbounceURL":"https://magazine.bioprocessintl.com/?pk=WEBS23B","elnConfig":{"newsletter":{"subscribeForm":{"title":"Subscribe to Our Newsletters","subtitle":"Subtitle"},"subscribeConfirm":{"title":"Subscribe to Our Newsletters","subtitle":"Subtitle"}}}},"isOneTrustLoaded":false}},"routes/$topic.$slug._index":{"isRequestedByGoogleBot":false,"iirisRecommendationConfig":{"id":"widget-1708438882494","division":"ic","brandFamily":"lifesciences","entityTagBackground":"#333333BF","dateFormat":"DD/MM/YYYY","showBy":"","showTime":"","borderRadius":"5","imageWidth":"324","imageHeight":"182","dateTimeBgcolor":"#ffffff","dateTimeFontColor":"#767676","imagePosition":"vertical","dropShadow":"#FFEB00","dateTimeFontsize":"12","entityTagBorderColor":"#333333","borderColor":"#e6e6e6","showdate":"yes","redirectMode":"same","recipe":"related-items","brandName":"bioprocessintl"},"isUserEntitled":false,"metadata":{"type":"podcast","uid":"blta64a61e10655f983","aid":"707126","reg":"anonymous","pterm":{"main":"BPI Podcasts","parent":"Bioprocess Insider","grandparent":{"title":""},"additional":[{"type":"TopicPrimary","title":"Bioprocess Insider","url":"/bioprocess-insider"},{"type":"TopicSecondary","title":"Upstream \u0026 Downstream Processing","url":"/bioprocess-insider/upstream-downstream-processing","parentTopic":{"type":"TopicPrimary","title":"Bioprocess Insider"}}]},"contentFormat":"News","buyersJourney":"","contributor":[{"title":"Dan Stanton","name":"Dan Stanton","companyName":"","role":"Editorial director","avatar":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg","link":"/author/dan-stanton","tagLine":"Editorial director","summary":[{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Journalist covering the international biopharmaceutical manufacturing and processing industries."},{"type":"hardBreak"},{"type":"text","text":"Founder and editor of Bioprocess Insider, a daily news offshoot of publication Bioprocess International, with expertise in the pharmaceutical and healthcare sectors, in particular, the following niches: CROs, CDMOs, M\u0026A, IPOs, biotech, bioprocessing methods and equipment, drug delivery, regulatory affairs and business development."},{"type":"hardBreak"},{"type":"hardBreak"},{"type":"text","text":"From London, UK originally but currently based in Montpellier, France through a round-a-bout adventure that has seen me live and work in Leeds (UK), London, New Zealand, and China."}]}]}],"gatedWithExternalForm":false,"gatedWithSiteReg":false,"paidGating":false,"sponsorName":""},"template":{"breadcrumbs":[{"url":"/","title":"Home"},{"url":"/bioprocess-insider/bpi-podcasts","title":"BPI Podcasts"}],"topics":[{"__typename":"TopicSecondary","title":"BPI Podcasts","url":"/bioprocess-insider/bpi-podcasts","parentTopic":{"title":"Bioprocess Insider"}},{"__typename":"TopicPrimary","title":"Bioprocess Insider","url":"/bioprocess-insider"},{"__typename":"TopicSecondary","title":"Upstream \u0026 Downstream Processing","url":"/bioprocess-insider/upstream-downstream-processing","parentTopic":{"title":"Bioprocess Insider"}}],"subBrand":null,"searchParams":{},"summary":"","title":"Podcast: Lumen using spirulina to make ‘edible’ antibody drugs","mobileHeadline":"Podcast: Lumen using spirulina to make ‘edible’ antibody drugs","authoredBy":"Dan Stanton","authoredOn":"2023-12-28T13:38:28+00:00","oldUrl":"https://bioprocessintl.com/bioprocess-insider/podcasts-bioprocess-insider/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs/","buyersJourney":"","contributors":[{"title":"Dan Stanton","name":"Dan Stanton","companyName":"","role":"Editorial director","avatar":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt94f438d7a1593228/66d9d6cbd45ddd70d3fd093a/Square_BPI2024Vienna_(c)schedl_b_and_w.jpg","link":"/author/dan-stanton","tagLine":"Editorial director","summary":[{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Journalist covering the international biopharmaceutical manufacturing and processing industries."},{"type":"hardBreak"},{"type":"text","text":"Founder and editor of Bioprocess Insider, a daily news offshoot of publication Bioprocess International, with expertise in the pharmaceutical and healthcare sectors, in particular, the following niches: CROs, CDMOs, M\u0026A, IPOs, biotech, bioprocessing methods and equipment, drug delivery, regulatory affairs and business development."},{"type":"hardBreak"},{"type":"hardBreak"},{"type":"text","text":"From London, UK originally but currently based in Montpellier, France through a round-a-bout adventure that has seen me live and work in Leeds (UK), London, New Zealand, and China."}]}]}],"readTime":0,"socialShare":[{"type":"Linkedin","url":"https://www.linkedin.com/sharing/share-offsite/?url=https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"},{"type":"Twitter","url":"http://www.twitter.com/intent/tweet?url=https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs"},{"type":"Email","url":"mailto:?subject=Podcast: Lumen using spirulina to make ‘edible’ antibody drugs\u0026body=I%20thought%20the%20following%20from%20BioProcess%20International%20might%20interest%20you.%0D%0A%0D%0A%20Podcast%3A%20Lumen%20using%20spirulina%20to%20make%20%E2%80%98edible%E2%80%99%20antibody%20drugs%0D%0Ahttps%3A%2F%2Fwww.bioprocessintl.com%2Fbpi-podcasts%2Fpodcast-lumen-using-spirulina-to-make-edible-antibody-drugs"}],"publishedDate":"2022-07-25T09:05:06.000Z","keywords":[],"atAGlance":[],"bodyJson":[{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","marks":[{"type":"bold"}],"text":"We sit down with Lumen Biosciences CEO Brian Finrow to discuss how his company hopes to use its spirulina-based platform to develop drugs targeting gastrointestinal disorders."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Lumen Biosciences is a biotech looking to unlock the full potential of biologic drugs, whose promise has been held back by the lack of scalable technology."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"The firm is developing ‘oral antibodies’ using its platform based on spirulina– the protein-rich cyanobacteria touted by many health enthusiasts as a ‘superfood’ – to create tiny factories that churn out therapeutic antibodies."}]},{"type":"ad","pos":"300_1v_article"},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"image","attrs":{"textAlign":"left","src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt3ffbd080cf28499f/658d74c5f5ee23040a1a8568/spirulina--300x241.jpg","alt":"spirulina--300x241.jpg","title":null,"style":{"float":"center"}}}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Image: Stock Photo Secrets"}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"More details can be found in the text box below, but as part of the BioProcess International Theater at BIO in San Diego last month, I spoke with CEO and co-founder Brian Finrow."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Listen to the full interview as part of the Bioprocess Insider Expression Platform podcast here, on "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://podcasts.apple.com/fr/podcast/the-bioprocess-insider-expression-platform/id1549869188","target":"_blank","rel":"noopener","class":null}}],"text":"Apple"},{"type":"text","text":", "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://music.amazon.com/podcasts/f5eaf75c-1b97-41e0-ba63-3c31ef68ebeb/the-bioprocess-insider-expression-platform","target":"_blank","rel":"noopener","class":null}}],"text":"Amazon"},{"type":"text","text":", "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://open.spotify.com/show/0Sh7c6SJOJ7nsFLNPuW7B0","target":"_blank","rel":"noopener","class":null}}],"text":"Spotify"},{"type":"text","text":", or wherever you get your podcasts."}]},{"type":"table","content":[{"type":"tableRow","content":[{"type":"tableCell","attrs":{"colspan":1,"rowspan":1,"colwidth":null},"content":[{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","marks":[{"type":"bold"}],"text":"Spirulina-based biologics"}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Engineering a food product to produce a biologic drug is not a new idea. Earlier efforts failed, mostly because it’s hard to produce enough of the biologic. If a patient must eat the equivalent of an acre of a crop a day to receive therapeutic benefit, it’s just not feasible as a drug. Spirulina has been grown at scale in the US since the 1970s, which means that it has a long track record and plenty of safety data. Furthermore, sprirulina is packed with protein so a little sprinkle goes a long way. The biggest challenge is figuring out a way to make those protein stores therapeutic."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Antibodies are proteins. Lumen gets spirulina to produce them by engineering the cyanobacteria’s genome. But the company doesn’t use CRISPR or some other gene-editing technique, which would only make antibody production more complex and more expensive. The Lumen technology takes a gene that codes for a desired protein and inserts it into one or more designated locations in the spirulina genome. As spirulina grow and divide, they make the antibodies and pack them inside their cell membranes. Engineering also controls how much of a desired protein is produced in each cell."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Spirulina only need water and light to grow. The spirulina that’s sold by grocers and health food stores is grown in outdoor ponds, then dried. Lumen produces its spirulina much the same way, though it does so in a controlled 20,000 square-foot-indoor facility in Seattle’s Fremont neighborhood. The end product is a greenish powder of dead, desiccated cells."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Traveler’s diarrhea is Lumen’s lead disease target. The company aims to prevent the condition from developing in the first place. The Lumen drug, a capsule filled with the green powder, is intended to be taken by a traveler once a day. In the gut, the cell membrane breaks down, releasing its antibody payload. Those antibodies stand ready to bind to and neutralize toxic bacteria they encounter. The antibodies and pathogens are then swept from the gastrointestinal tract with bodily waste. In Phase I testing, the drug candidate was shown to be safe and well tolerated by patients."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Lumen’s pipeline also includes candidates for norovirus and "},{"type":"text","marks":[{"type":"italic"}],"text":"Clostridioides difficile"},{"type":"text","text":" infection, both of which the company aims to neutralize in the gut. There are no FDA-approved norovirus therapies or vaccines."}]}]}]}]}],"contentType":"Podcast","uid":"blta64a61e10655f983","sponsored":{"logoUrl":"","url":"","alt":"","title":"","campaignURL":"","isSponsored":false,"gateWithSiteReg":false,"gateWithExternalForm":"None","externalFormID":""},"featuredImage":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt5354aa5ebeb2d982/658d74c62ef467040a88a0ed/spirulina-.jpg","alt":"Podcast: Lumen using spirulina to make ‘edible’ antibody drugs","caption":"Image: Stock Photo Secrets","creditTo":""},"contentFormat":{"title":"News"},"seriesTaxonomy":[{"uid":"bltd8dae020ccd5c68e","title":"Podcasts","url":"/series/podcasts"},{"uid":"bltc7336db523bd7680","title":"Upstream and Downstream Processing","url":"/series/upstream-and-downstream-processing"}],"programTaxonomy":[{"logo":{"url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blte7957c3a38c95fac/65c500a3a2f62c040a2fed1f/Insider-Header-2019-700w.jpg"},"logoAltText":"BioProcess Insider","tagline":"","programName":"BioProcess Insider","url":"/program/bioprocess-insider","uid":"blt6d74e2f641f0d639","sidebarModuleIds":["bltfe1a46ba3d37526a","blt1977c78d09e07df1","bltf94443650cd11acb","blt3ea64d3a54656d7d","blt7697767cd0d0e631"],"sidebarOptions":"custom","isBranded":true,"mode":"logo"}],"sidebarModules":[{"type":"module_content_cards","data":{"title":"Webinars","moduleLabel":"","variant":"default","contents":[{"type":"contentPreview","data":{"contentType":"ExternalLink","variant":"card-horizontal","thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png","alt":"Ask the Expert webcasts"},"articleName":"Register Now: Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges","mobileHeadline":"Register Now: Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges","articleUrl":"https://bpi.bioprocessintl.com/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges","listPageUrl":"https://bpi.bioprocessintl.com/evaluation-of-a-new-multimodal-anion-exchange-resin-for-emerging-biotherapeutic-process-challenges","linkAttrs":{"target":"_blank","rel":"nofollow"},"date":"Nov 1, 2024","webinarStartTime":"","categoryName":"ATE Webcasts","categoryUrl":"/ate-webcasts","contributors":[],"timeRead":0,"paidGating":null}},{"type":"ad","data":{"pos":"native_right_1v"}},{"type":"contentPreview","data":{"contentType":"ExternalLink","variant":"card-horizontal","thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png","alt":"Ask the Expert webcasts"},"articleName":"Register Now: Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality","mobileHeadline":"Register Now: Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality","articleUrl":"https://bpi.bioprocessintl.com/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality","listPageUrl":"https://bpi.bioprocessintl.com/linking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality","linkAttrs":{"target":"_blank","rel":"nofollow"},"date":"Nov 8, 2024","webinarStartTime":"","categoryName":"ATE Webcasts","categoryUrl":"/ate-webcasts","contributors":[],"timeRead":0,"paidGating":null}},{"type":"contentPreview","data":{"contentType":"ExternalLink","variant":"card-horizontal","thumbnail":{"src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt78e2c8c20086aef1/66b4fbe1593f0647e02b9a02/Website-ATE-Register-logo-2024-1280.png","alt":"Ask the Expert webcasts"},"articleName":"Register Now: Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality","mobileHeadline":"Register Now: Navigating Biopharma Commercialization: The Interplay of Regulatory Affairs, Process Development, and Manufacturing to Ensure Drug Quality","articleUrl":"https://bpi.bioprocessintl.com/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality?utm_source=bpi\u0026utm_medium=social\u0026utm_campaign=ATE-webcasts","listPageUrl":"https://bpi.bioprocessintl.com/navigating-biopharma-commercialization-the-interplay-of-regulatory-affairs-process-development-and-manufacturing-to-ensure-drug-quality?utm_source=bpi\u0026utm_medium=social\u0026utm_campaign=ATE-webcasts","linkAttrs":{"target":"_blank","rel":"nofollow"},"date":"Nov 12, 2024","webinarStartTime":"","categoryName":"ATE Webcasts","categoryUrl":"/ate-webcasts","contributors":[],"timeRead":0,"paidGating":null}},{"type":"ad","data":{"pos":"native_right_2v"}}],"dateDisplay":"hide","contributorDisplay":"hide"},"adConfig":{"nativeAdOption":true}},{"type":"module_link_list","data":{"listOption":"Dynamic","listTitle":"Latest Content","icon":"Checkmark","externalFeed":"","ctaButton":{"ctaButtonLink":"","ctaButtonText":""},"openInNewTab":false,"articles":[{"contentType":"Article","title":"Vaccine makers sanguine amid threat from US health nominees RFK Jr. and Dr. Oz","url":"/regulations/vaccine-makers-sanguine-amid-threat-from-us-health-nominees-rfk-jr-and-dr-oz","isExternalLink":false,"readTime":5,"publishedDate":"2024-11-27T09:21:43.000Z","eventDate":"","webinarStartTime":""},{"contentType":"Article","title":"Social media murmurs: Industry contemplates supply chain post-BIOSECURE","url":"/global-markets/social-media-murmurs-industry-contemplates-supply-chain-post-biosecure","isExternalLink":false,"readTime":3,"publishedDate":"2024-11-27T09:08:41.000Z","eventDate":"","webinarStartTime":""},{"contentType":"Journal","title":"Driving Innovation in Drug Development and Production","url":"/sponsored-content/driving-innovation-in-drug-development-and-production","isExternalLink":false,"readTime":0,"publishedDate":"2024-11-26T21:12:49.000Z","eventDate":"","webinarStartTime":""},{"contentType":"Article","title":"CHOP teams with INCA to bring CAR-T therapies to children in Brazil","url":"/facilities-capacity/chop-teams-with-inca-to-bring-car-t-therapies-to-children-in-brazil","isExternalLink":false,"readTime":4,"publishedDate":"2024-11-25T19:30:19.000Z","eventDate":"","webinarStartTime":""}]}},{"type":"module_linked_image","data":{"title":"Get the News","ctaButton":{"buttonTitle":"SUBSCRIBE","buttonUrl":"https://bpi.bioprocessintl.com/bioprocess-insider-subscription"},"contentDisplayOption":"large","logos":[{"url":"https://bpi.bioprocessintl.com/bioprocess-insider-subscription","src":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt52ab5c92a7623abe/672a934f35a2cd6b857059f1/Insider-Subscribe-1280x720-fullv2.png","altText":""}],"moduleLocation":"sidebar"}},{"type":"module_content_spotlight","data":{"variant":"reversed","mode":"light","textAlignment":"center","moduleDesign":"standard","contentType":"Podcast","listPageUrl":"/podcasts","content":{"keywords":[],"image":{"url":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt6e2069d504af847e/66b1e8d09cb2930a4db78268/VOB_scale_ready.jpeg","altText":""},"summary":"Content Spotlight","heading":"Podcast: Sustainability is about health equity, says ScaleReady and Germfree","mobileHeading":"Podcast: Sustainability is about health equity, says ScaleReady and Germfree","articleBody":[{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","marks":[{"type":"bold"}],"text":"ScaleReady and Germfree discuss the need to rethink sustainability and move towards a more standardized and simplistic manufacturing model to ensure health equity can be achieved."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"This episode of our monthly podcast "},{"type":"text","marks":[{"type":"italic"}],"text":"Voices of Biotech "},{"type":"text","text":"brings you an interesting conversation with Carol Houts, chief strategy officer at Germfree and Josh Ludwig, global director commercial operations at ScaleReady."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"Together, they discuss how sustainability measures can increase patient care and access through decentralized manufacturing models, which can reduce the time, space, and cost associated with producing cell and gene therapies (CGTs) and other modalities."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"The conversation about sustainability leads into a discussion about the ecosystem in the life sciences space."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"While both acknowledged and spoke in-depth about the advantages of educating the industry and shifting towards a more decentralized manufacturing model, Ludwig and Houts did not shy away from discussing some of the challenges the industry faces. These include the shortage of talent in the space, the element of many players still “figuring it out” as sustainability is not an individual issue but a collective one, and the issue of drug shortages."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"The pair ended the podcast with some thought-provoking statements regarding the need to rethink what sustainability means and urged how standardization is really the key to achieving better patient care and access."}]},{"type":"paragraph","attrs":{"textAlign":"left"},"content":[{"type":"text","text":"The latest episode can be found here or through the "},{"type":"text","marks":[{"type":"italic"}],"text":"BioProcess Insider Expression Platform"},{"type":"text","text":" at, "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://open.spotify.com/show/0Sh7c6SJOJ7nsFLNPuW7B0","target":"_blank","rel":null,"class":null}}],"text":"Spotify"},{"type":"text","text":", "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://podcasts.apple.com/fr/podcast/the-bioprocess-insider-expression-platform/id1549869188","target":"_blank","rel":null,"class":null}}],"text":"Apple iTunes"},{"type":"text","text":", "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkLnBvZGJlYW4uY29tL2Jpb3Byb2luc2lkZXIvZmVlZC54bWw/episode/YmlvcHJvaW5zaWRlci5wb2RiZWFuLmNvbS8xODZhZGExNS1hNTQ4LTMyMGMtOGJhZi00YWM4ZWQxODdiMjk?sa=X\u0026ved=0CAUQkfYCahcKEwiosu2Xm_r3AhUAAAAAHQAAAAAQFg","target":"_blank","rel":null,"class":null}}],"text":"Google podcasts"},{"type":"text","text":", or wherever you get your podcasts."}]},{"type":"paragraph","attrs":{"textAlign":"left"}}],"articleSummary":"ScaleReady and Germfree discuss the need to rethink sustainability and move towards a more standardized and simplistic manufacturing model to ensure health equity can be achieved. ","body":"ScaleReady and Germfree discuss the need to rethink sustainability and move towards a more standardized and simplistic manufacturing model to ensure health equity can be achieved. ","callToAction":{"text":"Listen Now","url":"/bpi-podcasts/podcast-sustainability-is-about-health-equity-says-scaleready-and-germfree"},"linkAttrs":{},"articleUrl":"/bpi-podcasts/podcast-sustainability-is-about-health-equity-says-scaleready-and-germfree","categoryName":"BPI Podcasts","categoryUrl":"/bioprocess-insider/bpi-podcasts","date":"2024-08-06T09:35:37.000Z","paidGating":null}}}],"relatedEvents":[],"topicSelector":{"mainTopic":{"type":"TopicSecondary","title":"BPI Podcasts","url":"/bioprocess-insider/bpi-podcasts","parentTopic":{"type":"TopicPrimary","title":"Bioprocess Insider"}},"additionalTopics":[{"type":"TopicPrimary","title":"Bioprocess Insider","url":"/bioprocess-insider"},{"type":"TopicSecondary","title":"Upstream \u0026 Downstream Processing","url":"/bioprocess-insider/upstream-downstream-processing","parentTopic":{"type":"TopicPrimary","title":"Bioprocess Insider"}}]},"paidGating":{"isPaidContent":false,"paidProductTaxonomies":[]},"errorModal":{"showErrorModal":false,"errorTitle":"Oops! An error has occurred","errorDescription":"The connection on our end has been interrupted. Please refresh the page and try again."},"podcast":{"podcastId":"","podcastService":"embed","podcastLink":"","podcastEmbed":"\u003ciframe loading=\"lazy\" width=\"100%\" height=\"150\" style=\"border: none; min-width: min(100%, 430px);\" title=\"Snippets from BIO: Lumen CEO talks edible antibodies\" allowtransparency=\"true\" scrolling=\"no\" data-name=\"pb-iframe-player\" src=\"https://www.podbean.com/player-v2/?i=q46c6-127b7c4-pb\u0026amp;from=pb6admin\u0026amp;share=1\u0026amp;download=1\u0026amp;rtl=0\u0026amp;fonts=Arial\u0026amp;skin=1\u0026amp;font-color=auto\u0026amp;logo_link=episode_page\u0026amp;btn-skin=7\"\u003e\u003c/iframe\u003e","duration":{"duration":"00:00:00"}},"isUserEntitled":false,"isGatedAsPaid":false},"schema":[{"@context":"https://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.bioprocessintl.com"},{"@type":"ListItem","position":2,"name":"BPI Podcasts","item":"https://www.bioprocessintl.com/bioprocess-insider/bpi-podcasts"}]}],"seo":{"canonicalUrl":"https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs","metaDescription":"Lumen Biosciences hopes to use its spirulina-based platform to develop drugs targeting gastrointestinal disorders.","metaTitle":"Lumen using spirulina to make ‘edible’ antibodies - BioProcess Insider","noIndex":false,"imageUrl":"https://eu-images.contentstack.com/v3/assets/blt0a48a1f3edca9eb0/blt5354aa5ebeb2d982/658d74c62ef467040a88a0ed/spirulina-.jpg?disable=upscale\u0026width=1200\u0026height=630\u0026fit=crop","keywords":"BPI Podcasts, Bioprocess Insider, Upstream \u0026 Downstream Processing"},"gtm":{"loadEvent":{"attributes":{"events":[],"subBrand":"","seo":{"canonicalURL":"https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs","hideFromSearchEngines":false},"sponsored":{"name":"","campaignURL":"","isSponsored":false,"gateWithSiteReg":false,"gateWithExternalForm":"None","externalFormID":""},"legacy":{"destinationPath":"https://bioprocessintl.com/bioprocess-insider/podcasts-bioprocess-insider/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs/","issueDate":"Dec 28, 2023","contributor":"Dan Stanton"}},"category":{"buyerJourney":"","contentFormat":"News","pageType":"podcast","keyword":[],"series":[{"name":"Podcasts"},{"name":"Upstream and Downstream Processing"}],"programName":"BioProcess Insider","primaryTerm":{"parent":"Bioprocess Insider","child":"BPI Podcasts","grandchild":""},"secondaryTerm":[{"parent":"Bioprocess Insider","child":"","grandchild":""},{"parent":"Bioprocess Insider","child":"Upstream \u0026 Downstream Processing","grandchild":""}]},"pageInfo":{"pageID":"blta64a61e10655f983","pageName":"Podcast: Lumen using spirulina to make ‘edible’ antibody drugs","destinationURL":"https://www.bioprocessintl.com/bpi-podcasts/podcast-lumen-using-spirulina-to-make-edible-antibody-drugs","issueDate":"Jul 25, 2022","contributor":[{"companyName":"","displayName":"Dan Stanton","jobTitle":"Editorial director","name":"Dan Stanton"}]}}},"isLivePreview":false}},"actionData":null,"errors":null}};</script><script type="module" async="">import "/build/manifest-A2F38A42.js"; import * as route0 from "/build/root-TPDAOOC5.js"; import * as route1 from "/build/routes/$topic.$slug._index-J4IJ2FVO.js"; window.__remixRouteModules = {"root":route0,"routes/$topic.$slug._index":route1}; import("/build/entry.client-SFHSSSEN.js");</script><script async="" defer="" src="https://connect.facebook.net/en_US/sdk.js#xfbml=1&version=v3.2"></script><script async="" defer="" src="https://www.instagram.com/embed.js"></script></body></html>