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Electron Microscopy</span></a><meta ></span> <span aria-label="breadcrumb separator">/</span> <span class="breadcrumb-current-title">Meeting the Expanding Nanoparticle Analysis Needs of Materials Scientists</span></div></div></header><div class="site-inner"><div class="content-sidebar-wrap"><main class="content"><article class="post-11107 post type-post status-publish format-standard has-post-thumbnail category-energy-dispersive-x-ray-spectroscopy category-transmission-electron-microscopy tag-nanomaterials entry" aria-label="Meeting the Expanding Nanoparticle Analysis Needs of Materials Scientists"><header class="entry-header"><h1 class="entry-title">Meeting the Expanding Nanoparticle Analysis Needs of Materials Scientists</h1> <span class="post-info-author"> By <a href="https://www.thermofisher.com/blog/author/yuririkers/" title="Posts by Yuri Rikers" rel="author">Yuri Rikers</a> </span> <span class="post-info-date"> 03.25.2021 </span> </header><div class="entry-content"><p>Materials scientists analyzing an ever-expanding array of materials are looking for solutions that deliver precise, statistically relevant data at the nanoscale. Whether they’re conducting nanoparticle analysis on metals, catalysis, foods, paints or asbestos, they need a tool that performs large-area analysis with high-resolution imaging, and better and faster statistics.</p> <p>Our Automated Particle Workflow (APW) is an all-in-one package that streamlines imaging and chemical analysis workflows for industrial, academic and government labs that revolutionizes product development by quickly screening new materials. It not only addresses multi-material analysis needs, but also features greater automation with enhanced data collection, delivering a better return on investment by lowering cost per measurement.</p> <p>APW incorporates seamlessly into the transmission electron microscope (TEM) workflow, enabling research inquiries to be addressed quickly and efficiently. In conjunction with APW, techniques like energy-dispersive X-ray spectroscopy (EDS) support research on a wide range of materials and enable unattended data collection for nanoparticle morphology, chemical composition, and structural information. Nanoparticle analysis with our user-friendly APW addresses the need for greater nanoscale results over a large area and, when combined with EDS mapping software, facilitates more accurate data capture with more detailed statistics than what’s currently achievable—without the need for a TEM expert.</p> <p><img decoding="async" class="alignnone size-full wp-image-11108 aligncenter" title="Infographic showing the steps of the APW workflow for nanoparticle analysis." src="https://www.thermofisher.com/blog/materials/wp-content/uploads/sites/7/2021/03/2021-MS-APW-Infographic-268230_Generic_v1.4-WEB-Enlarged-copy-1200x728-1.png" alt="Infographic showing the steps of the APW workflow for nanoparticle analysis." width="1200" height="728" aria-describedby="infographic_long" srcset="https://www.thermofisher.com/blog/materials/wp-content/uploads/sites/7/2021/03/2021-MS-APW-Infographic-268230_Generic_v1.4-WEB-Enlarged-copy-1200x728-1.png 1200w, https://www.thermofisher.com/blog/materials/wp-content/uploads/sites/7/2021/03/2021-MS-APW-Infographic-268230_Generic_v1.4-WEB-Enlarged-copy-1200x728-1-300x182.png 300w, https://www.thermofisher.com/blog/materials/wp-content/uploads/sites/7/2021/03/2021-MS-APW-Infographic-268230_Generic_v1.4-WEB-Enlarged-copy-1200x728-1-1024x621.png 1024w, https://www.thermofisher.com/blog/materials/wp-content/uploads/sites/7/2021/03/2021-MS-APW-Infographic-268230_Generic_v1.4-WEB-Enlarged-copy-1200x728-1-768x466.png 768w" sizes="(max-width: 1200px) 100vw, 1200px" /></p> <p style="text-align: center"><em>Our infographic highlights how APW enhances the TEM workflow.</em></p> <details> <summary><strong>Click here for accessibility descriptions >></strong></summary> <p id="infographic_long">This is an infographic showing the steps of the Automated Particle Workflow connected by a long series of chevrons. The beginning and end of the workflow are connected by a large red arrow labeled:<br /> “From sample to particle statistics, automated and unattended”</p> <p>The beginning of the workflow is labeled “Automated workflow” and features a stylized silhouette of two people with the following text overlaid:<br /> “Better statistics, faster<br /> Perform large-area, high-resolution imaging and data acquisition. The Thermo Scientific Automated Particle Workflow (APW) streamlines the workflow from sample to particle analysis by automating data acquisition, particle segmentation, and statistical analysis of morphological and chemical parameters.”<br /> Beneath the text is a labeled illustration of the Spectra (S)TEM and Talos (S)TEM.</p> <p>The “Automated workflow” label is connected to a section labeled “1. Acquisition” with the following text:<br /> “Thermo Scientific Maps and Velox Software enable the acquisition of large-area, high-resolution scanning transmission electron microscopy (STEM) images and energy dispersive X-ray spectroscopy (EDXS) maps in a fully automated way.”<br /> The segment of the chevron above the text contains a greyscale TEM image of nanoparticles. Above the chevron is an illustration of a computer labeled “Maps Software powered by Velox”</p> <p>The “1. Acquisition” label is connected to a section labeled “2. Segmentation” with the following text:<br /> “During automated, unattended acquisition of STEM images and EDS maps, Maps Software and Thermo Scientific Avizo2D Software use the image and chemical information from the STEM and EDS maps to find and classify nanoparticles based on morphology and chemical composition.”<br /> The segment of the chevron above the text shows nanoparticle analysis with a colorized TEM image of nanoparticles. The colors corresponding to particle size.</p> <p>The “2. Segmentation” label is connected to a section labeled “3. Interpretation” with the following text:<br /> “Avizo2D Visualization Software allows you to analyze the segmented data to generate statistics such as size, surface area, perimeter, distribution, and chemical composition.”<br /> Below the text is an illustration of a computer labeled “Avizo2D Software.” The final segment of the chevron transitions into a stylized series of bars intended to imply a bar graph of the nanoparticle distribution.</p> <p>At the end of the workflow chevron is a list of benefits:<br /> – Get statistics on more than 500 particles per hour<br /> – Rapidly screen new products and processes<br /> – Significantly improve repeatability<br /> – Run the TEM 24/7, unattended</p> </details> <p>Visit our <a href="https://ter.li/gw23nm">website</a> to download the infographic and learn more about how APW accelerates Materials Science research.</p> <p>Yuri Rikers is a Product Marketing Manager at Thermo Fisher Scientific.</p> <p><em> </em>///</p> <p>Connect with an expert: 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