CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="390"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "www.researchgate.net",cType: 'managed',cRay: '9141bf7e286cce81',cH: 'qMkP6QTY9iqJtHvZfQAn6RuxsppjR0MLKJnxdK_voJY-1739920829-1.2.1.1-sbRrxEx73K.E8g_4TMCQqWIU_1Movd9AcOe6MV9GdFRDM81KfZl5RYQnRg2ChTLD',cUPMDTk: "\/profile\/Toshihiko-Ishimitsu\/publication\/334895492_The_Japanese_Society_of_Hypertension_Guidelines_for_the_Management_of_Hypertension_JSH_2019\/links\/5de8ad5192851c836462a59d\/The-Japanese-Society-of-Hypertension-Guidelines-for-the-Management-of-Hypertension-JSH-2019.pdf?__cf_chl_tk=.FrgHbrjnowTVBtHjnlXIsSkZyjhniNQYzzwTMJmYqc-1739920829-1.0.1.1-BNA6_ylzV2GeoPM2MPqF9E..tz9rHjsZqHquxIz0gHw",cFPWv: 'g',cITimeS: '1739920829',cTTimeMs: '1000',cMTimeMs: '390000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "unsupported-browser",fa: "\/profile\/Toshihiko-Ishimitsu\/publication\/334895492_The_Japanese_Society_of_Hypertension_Guidelines_for_the_Management_of_Hypertension_JSH_2019\/links\/5de8ad5192851c836462a59d\/The-Japanese-Society-of-Hypertension-Guidelines-for-the-Management-of-Hypertension-JSH-2019.pdf?__cf_chl_f_tk=.FrgHbrjnowTVBtHjnlXIsSkZyjhniNQYzzwTMJmYqc-1739920829-1.0.1.1-BNA6_ylzV2GeoPM2MPqF9E..tz9rHjsZqHquxIz0gHw",md: "UIp1lqtABSj97oLR5tkwXODaV9MnWrTKAjyEINdmJPA-1739920829-1.2.1.1-HWHS88RanNG3wZ99bwGICopb4BDCgfJTE6EnbfDmphUKTS4uT4OwqZGafR4xpWbc63Wt_MFAFG0h4aJh0vyZYNRDNVOnsxLj_bcuoJIHXLsWMMaEoiktnVOQ.FmwEoe5Sfg16j8Au6M6IHffmcxpEZhe2lS4tdggkYt5WaODYEQcjYi6zgGGzVoVY9qtLEnRat8DQLuVs3y0mrLi2Kzy7Txana0SIM4KGR1CyZ_DUn7VMWDRK7IT5SUciWwyWUfuMJkZC.0hWV9KMA1N7P7lLSnWbtc0BXY.pJ.WnjEIMijptoirvcBhf9qverIxOmWCN_Nm2rS2_wbLLFz3lADdhjfojfxL2OFxB9IPLt1xpC1hUQGmen41hZg0xHsB7WXMdvEU0wgiBc0avcSyUPj8Wgw5KcVAaTYq1iwTO8clySNuPdRRglBBVWBJkNITJAtSh36GC2sDyhnpO80LXBxcRsewtyOhBUkcnvnfvYmZNoKBdcOU.OPEaDymk0cC8e6GhY38rEjIDge97Azfb7YZFJQnjGsjvYrsnUpy0FSuJQzQ.Zl806tfxApxeo90JR766D2B1LGa1Bq.AyKKk04hOMhLQSXA1CaOBENg5.UzKGMfwb3QhvCZHqBgczS2UxOPNyM1iaan41kWrlbxmeddlqq2GtthzObSCj3udz5RbJmD7439SA9Svgk3jSpQKK.Q_mxltrAaiIArgamYLlKq7Pc9udLK2tTEAVK9pYmlIWAuBGoXmADzZR6gTDjXDQhWmD5b03YUSBcpjaDKgHDg6HNrM.WiSaU0kmF7xgIlvV8SO.XQuRLwfv0BVfOUiSFCrbVu3rAFOrYQaQxcpnOIsWatACvaqIcay4n43LldVAJTNURPa0KB9q_owH4JS40KJWv8M4Apcq.lvuDbUdJjdSp.9vf4YVrkVtNd2p0.tLF8K4aUS_dklbRdZP_gwk4b4Y1mOWNhWJmuGf0F6SZFoPZXphlYfMimoBY0asLL3DYvnhfyJwZNhJHb.VDpL9iWcpESO5s719vFEs3AnmNrmDhWYk1CI4YPOIDG5E2oAYzPQ7RGiRiRLMbFxy10CUb_dzjcauxxzS4.Rz9ekZrTclFZL2QNx1twc6JhyqbCVx3cBkZYZS4hT2uPz6MYZigDCh2LIuXah0lLxzODGs4CQLMCTz8EC3_y4zWDEn96nizqAXDpGwPKUx6nm0OpsqK1Ll5w_ZTk_8._imRR5Q8ShNdpl4Y.h3vtMQg2sPoE22MbwkegIlTMLHRQxZEjteQGal_nVXaz7eNPs.hiS1j2RkKYDIqx6omCq46s.tSWGlvQlXdZH9rg4sStF_OJMNZn1gHCNV7fyyARL1BB8IwYn5M9rkmY9f6xTRqGx7V3v1HKwYtjv.fB1fIheXmC.3mx9X11N58IQYTOCHpCCsgeoUnjocfqmggiMsvQpXavC_0cWNtDAy6FiTSmtrtODu2Zh8MJ9r5fNAM1YBZSmNdfgXQXXdm_AZmYviLLT4.MuQEKIlYRNurmQejF3tKeudnT8wwwSYKgTVXtH6wckbwUXxpT1zKB1.PibVuPYfIlMGHd_WRJEuITeK7L59Qgx0zWhzgUTdv8jaQZnHoj_7E8ivvk2n3hO8iXxG_RF9qWR0p4smZH2pn8q_wcNBKVTre4mnyFa1z9vEhUcsw6aAYTJ55xIKC4jFko2TGvxWAMSJwF030iqHIcZBSMs5pYpt.T164BNfFC_Qqrx9ZcvYV2MLVIF7LzGI1UkEdK0onMjCDTBhZDDGxcDvHMo7rw5e6kCa5v6xXh4xch5dp2HY3bc.PRDkG9aJeiqZCyslfPuC0gnpAREJKps5cYgaVweuF4qYsqnTBqvyqI7u3XEJaX6r0OzmwItBgPfZHREuB9MPQtXFvZiub7a1U3y4KtS72iAu2fBG453rx.LGTTvzofKZk23W7F2.T4UkiAEwXkp8NYyuumgWf_FYX5Le05O_3ppO3w7ylCYqGbrVn_1.Db.8Er1tPc296ZWoZ.1twW98_ydkgALuR1DvPnglQihhnIm75iDKllofD4s3HelFcMhVKYvU9B__nyXxIs2b5l8kmLjaLQQmsbcrJuItmSQts4Ho74_r3Qe9wmdeuAaGGyuNnVrdlCnhwdDuElgaOgr4xWYYUFkFkbccB1_ahozrjAdNhBB6j7hM2MEuwJSrd4h02ekXSTqB5HhlZt1r3NHRPG32GPi6vS5p1qj2xNvPBdL7Czs.Ssg_kUqkTYfGoWpV6jMMmAr0Tsg9dB204W9fZA1iVAuFadPcVJEIuixtaZt5vhhagyD5gbuSh4.Tnz7owCOIv_AVQ8u9yhWMhcAzDQqNOdxT2XJ4FtyWIIAwL_dYSZCfr9Us.UFeRgw1nwtdUGG_xrk2zgDyZ0KkZB66d0hMjL6tPL2qWtsbVgNasgNlKkmSRN8Hk7kktzhdlE.g0TPsliZgRUCwxOA9QPJcRmc6nULDO82LYoTFucHkxS1dVIFd1L63Pd.qy0SKb0_Xagu2AryvmtKjr8xchSk8lqdutGMl._352p2CYQxspJgBYdDIhd3kSMadpTr89815ivIS4nLZRYMfc_9g6IpE0_hHQLjXH6zJLaMg8fxYYuci34IyP4sTzmsg1Wg.ybWwlRmGovsae0fSt5WZJUrHVAZ0gQTgmyh58kz_NXtv9sTl_Oix1ZdWxaX.twKIPIJcgKzYz7GDmObVmFzqVZuTgQ30SQ1WEwP9tpreHnbV0vqSccyy1dxjaSfVVa5anLI2GcDQq3P9xOPv0ySMWaqsptbAwdCyV1OQAPDDY2IyeAn_sNXUjpPnSPvqhapprV9sjRY5rzIyERq2oZ07chk2BzF9BpsqDiXG0azn7NzN_shurlbtNVEUMPz_0jUnjUMIqesp5J9wgKU7UZKVjHFewKc48gW0kN4ZSB4wL3UecBRV1AQDtAiGCZd.sJR9pW6GPAsVyxB5r0a_ySSngbwyRdIyhAgagqBPhpc1_okSy6_h3modZ3Y2fe9Vhg_ttfKf2TrrLAYQeMIGWHL6eNIPPlMRmvqTwOgmRH8Pits7pDopjBEWo52eXYwPvb_55QQNOLLfWWhr894B8TgLEH5I2J_ar1MlO5fkfOJgUCUqnzHPp3C5zkE896htHBreKFWOuYZBJcpn5dwTN.uHtMwwu_iDmd8fQbPC1QToR8_ZJrisOjWkllKsiZYiTOJkPV0JbBYEcxg6tF94hPkZQ67cHczwZuIAR_e_BBlEanF8S0k6e0WyHJmhExpUXO61vbPQ",mdrd: "mL9wdDUZElS0ynykymn5u73MnhOcfF5Fvp5zdfC2hx8-1739920829-1.2.1.1-K6SKWNl3jPqUXyT2jhWZt3mVfwWq4cXsv5w5a3cfpil1M5.xKj3JDaZ3MygmiQLkd.A975voMRrfpckToEru0AVXziwKlCVmdc5ZiS3YheMKx4.z6HVOW0cYvXxTKlS1NgK13xUIXIwIGJ6P6u38CgEAEGMarKfnc_yTgHWSm7sjm7QLWhTeMXyq1TWv2s494v9LMLwebTHRo8WnhBhMqbtLmjZxcC9Oevs0Z5SzXuXRInUZVlWd.ZzMmAOCaLjDG4fuwtBMMbzvGIJ6_2CKJXSb5QCqlUxgGG0K1tzv.pSRy0BlPIjM2lSXKwSoItLEJCERb7KLly0Fa1re8qebbyQGY2TSihiG.2SpFs20A9qu4Ukw4ES9InK_CT9sj0spZIiWdtsyldzmmMj1ehzdiZIpYB_N_PqJW8mtH2diu5oQIumngLy1xD93G9OXXx94KUH.zWonv6N_i9MBRxdTPMdkjOh_GZO8y8161gar3zRke1h4Z1N.FQTo_ANvwSR6NQNLq6F.2oWvu0Yhf3AIb66JwGTPSx9A_fq6OyW63vKe5sINkrOXlq_A2kAEkQUY1_5wPZ4CERat5U0ZmVjFPzASsVTGjj4mNEn8UG46Nz9WDEbQ0Tq_S78vRx2ippJGGsAG2ZIPrC8VB2Uz1PgkvS91BrViTNdzVBdyC1xAkcvTb8YVGCfgP.zGpASaOgdAxkH8SsJG1I9WGBRJ36oFEjGmMt4b0wTcYefaxiGUvMM2l1rBZAID6GGHKjm0Qjp10b3Uve2nyCKfgZW93fgPE4x5MAM7iNryaaibgin3NCIwAixnUxrRfJLjeuKgbn.OLJcyPYal6dr4zIYHD8yQJT4vx9EqvR278.dYmuCw7.FAH5JdsN0gUq_pCPzG3lnluY.tRjzz.cIloGE5aWReN9yLXGq0NzDg4D1oMk0KyvtSuZs7VetKGJKR6PPMdeK2HrV9H8uP86NbtDHXIBB706ERf6Dp8gFhJUeCVDW7aZb.lYqHlATp99n8IYJY8ZqroaJuHT7c.EE8YKV9k2reSIOXjfUXXtbE7hk6kc1j4Bndf1aoZPN39Z8.ayzEH5XwH5rjlP3UC9arxCs61Qn3ajvTjru012pEUKHLrx0ebCBF1F80uo93RlNpvJqb4FfeorrlqZbJtSUjY69gYom86WEf9aD7qhLYlK28SM6GXIPsI.AG.3MBtCknzgIAGD7B90we1pSJudYQClVIHzTBdp2PrIkHpo2aHNLtS3ZCd1O_cNkQBwoYio4s0odhalCWLDc9DcKwHPG55ejy4s.1sLK_1vw6E9NBOF75YhwER24lxSZxIZfR1iHICw2XQ7yDC6.MpfmrV4bzEZL64Ri.9xfaUVekcJnjgResMr3fwpqn9n5ahEMK5qCCbSwF7LB9i0PwjMwnncfJ8riKBZpTHfHttl9OrNSsCqWB7mNXKzLpElUxdM3kd.9gkocKX8O7p226kozlAPXsy3AqBrFWD__ihCGRDoDt6usVnYKH.nwG7adFEiYd7Z2APmyqbqKitxrgsdSwX1Nf3ST5aGoKvBxrtZpDUpQjGqUNiJ5w.Cd.CjZcC5U0XgVbRnt9mZ9sTD69TpLx.nHFKwgrkcR5843DZOnG2ExdwZSb0G7e3dWi3LAe47rGHTyRZ3RJoFrUmS04UzLXvAbGm_3fKzgX49udtx1HuRiXybuMtUJgUJX.TPSJHlC1IbVASRhDhKy726f66ktE2RQdwf3WwYSP1uPYnpsA8rLN34.6lUMTc5hoH6o4sSdTIl26UspK0_QHtfcxcbpTeU.00zSbpsFd_5O7J6oMNUKvTJOutWRConIo8HuLN7ErSBB2JfDtbOqtcS7E8VpYYDqsSRzAdEbwD81iHTdwh9LSSiGyHxUzAhopSbxSbx9TbW_9xQrppynh4Yl_Ees8FEzBNrRJja8OppXtdGDzq5hKEMiid9KctSyDnqQtY80xP9xd_uqiDYi_fIbl4BrNTyrT.D93BI_r0w"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=9141bf7e286cce81';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/profile\/Toshihiko-Ishimitsu\/publication\/334895492_The_Japanese_Society_of_Hypertension_Guidelines_for_the_Management_of_Hypertension_JSH_2019\/links\/5de8ad5192851c836462a59d\/The-Japanese-Society-of-Hypertension-Guidelines-for-the-Management-of-Hypertension-JSH-2019.pdf?__cf_chl_rt_tk=.FrgHbrjnowTVBtHjnlXIsSkZyjhniNQYzzwTMJmYqc-1739920829-1.0.1.1-BNA6_ylzV2GeoPM2MPqF9E..tz9rHjsZqHquxIz0gHw" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>