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Search results for: QCM nanosensor
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style="font-size:1.6rem;">Search results for: QCM nanosensor</h1> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Determination of Cyclic Citrullinated Peptide Antibodies on Quartz Crystal Microbalance Based Nanosensors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=Y.%20Saylan">Y. Saylan</a>, <a href="https://publications.waset.org/search?q=F.%20Y%C4%B1lmaz"> F. Y谋lmaz</a>, <a href="https://publications.waset.org/search?q=A.%20Denizli"> A. Denizli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>In this study, we have focused our attention on combining of molecular imprinting into nanofilms and QCM nanosensor approaches and producing QCM nanosensor for anti- CCP, chosen as model protein, using anti-CCP imprinted nanofilms. The nonimprinted nanosensor was also prepared to evaluate the selectivity of the imprinted nanosensor. Anti-CCP imprinted QCM nanosensor was tested for real time detection of anti-CCP from aqueous solution. The kinetic and affinity studies were determined by using anti-CCP solutions with different concentrations. The responses related with mass shifts (%m) and frequency shifts (%f) were used to evaluate adsorption properties. To show the selectivity of the anti-CCP imprinted QCM nanosensor, competitive adsorption of anti-CCP and IgM was investigated. The results indicate that anti- CCP imprinted QCM nanosensor has higher adsorption capabilities for anti-CCP than for IgM, due to selective cavities in the polymer structure.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Anti-CCP" title="Anti-CCP">Anti-CCP</a>, <a href="https://publications.waset.org/search?q=molecular%20imprinting" title=" molecular imprinting"> molecular imprinting</a>, <a href="https://publications.waset.org/search?q=QCM%20nanosensor" title=" QCM nanosensor"> QCM nanosensor</a>, <a href="https://publications.waset.org/search?q=rheumatoid%20arthritis." title=" rheumatoid arthritis."> rheumatoid arthritis.</a> </p> <a href="https://publications.waset.org/10000694/determination-of-cyclic-citrullinated-peptide-antibodies-on-quartz-crystal-microbalance-based-nanosensors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/10000694/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/10000694/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/10000694/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/10000694/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/10000694/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/10000694/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/10000694/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/10000694/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/10000694/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/10000694/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/10000694.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">2260</span> </span> </div> </div> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Quartz Crystal Microbalance Based Hydrophobic Nanosensor for Lysozyme Detection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=F.%20Yilmaz">F. Yilmaz</a>, <a href="https://publications.waset.org/search?q=Y.%20Saylan"> Y. Saylan</a>, <a href="https://publications.waset.org/search?q=A.%20Derazshamshir"> A. Derazshamshir</a>, <a href="https://publications.waset.org/search?q=S.%20Atay"> S. Atay</a>, <a href="https://publications.waset.org/search?q=A.%20Denizli"> A. Denizli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>A quartz crystal microbalance (QCM) nanosensor was developed to detect lysozyme enzyme by functionalizing its gold surface with the attachment of poly(methacroyl-L-phenylalanine) (PMAPA) nanoparticles. PMAPA was chosen as a hydrophobic matrix. The hydrophobic nanoparticles were synthesized by micro-emulsion polymerization method. Hydrophobic QCM nanosensor was tested for real time detection of lysozyme enzyme from aqueous solution. The kinetic and affinity studies were determined by using lysozyme solutions with different concentrations. The responses related with mass (Δm) and frequency (Δf) shifts were used to evaluate adsorption properties. </p> <p> </p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=HIC" title="HIC">HIC</a>, <a href="https://publications.waset.org/search?q=lysozyme" title=" lysozyme"> lysozyme</a>, <a href="https://publications.waset.org/search?q=nanosensor" title=" nanosensor"> nanosensor</a>, <a href="https://publications.waset.org/search?q=QCM." title=" QCM."> QCM.</a> </p> <a href="https://publications.waset.org/10000771/quartz-crystal-microbalance-based-hydrophobic-nanosensor-for-lysozyme-detection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/10000771/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/10000771/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/10000771/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/10000771/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/10000771/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/10000771/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/10000771/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/10000771/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/10000771/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/10000771/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/10000771.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">2171</span> </span> </div> </div> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Overview of CARDIOSENSOR Project on the Development of a Nanosensor for Assessing the Risk of Cardiovascular Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=A.C.%20Duarte">A.C. Duarte</a>, <a href="https://publications.waset.org/search?q=C.I.L.%20Justino"> C.I.L. Justino</a>, <a href="https://publications.waset.org/search?q=K.%20Duarte"> K. Duarte</a>, <a href="https://publications.waset.org/search?q=A.C.%20Freitas"> A.C. Freitas</a>, <a href="https://publications.waset.org/search?q=R.%20Pereira"> R. Pereira</a>, <a href="https://publications.waset.org/search?q=P.%20Chaves"> P. Chaves</a>, <a href="https://publications.waset.org/search?q=P.%20Bettencourt"> P. Bettencourt</a>, <a href="https://publications.waset.org/search?q=S.%20Cardoso"> S. Cardoso</a>, <a href="https://publications.waset.org/search?q=T.A.P.%20Rocha-Santos"> T.A.P. Rocha-Santos</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>This paper aims at overviewing the topics of a research project (CARDIOSENSOR) on the field of health sciences (biomaterials and biomedical engineering). The project has focused on the development of a nanosensor for the assessment of the risk of cardiovascular diseases by the monitoring of C-reactive protein (CRP), which has been currently considered as the best validated inflammatory biomarker associated to cardiovascular diseases. The project involves tasks such as: 1) the development of sensor devices based on field effect transistors (FET): assembly, optimization and validation; 2) application of sensors to the detection of CRP in standard solutions and comparison with enzyme-linked immunosorbent assay (ELISA); and 3) application of sensors to real samples such as blood and saliva and evaluation of their ability to predict the risk of cardiovascular disease.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Carbon%20nanotubes%20field%20effect%20transistors" title="Carbon nanotubes field effect transistors">Carbon nanotubes field effect transistors</a>, <a href="https://publications.waset.org/search?q=cardiovascular%20diseases" title=" cardiovascular diseases"> cardiovascular diseases</a>, <a href="https://publications.waset.org/search?q=C-reactive%20protein" title=" C-reactive protein"> C-reactive protein</a>, <a href="https://publications.waset.org/search?q=sensor." title=" sensor."> sensor.</a> </p> <a href="https://publications.waset.org/5490/overview-of-cardiosensor-project-on-the-development-of-a-nanosensor-for-assessing-the-risk-of-cardiovascular-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/5490/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/5490/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/5490/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/5490/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/5490/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/5490/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/5490/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/5490/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/5490/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/5490/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/5490.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">2042</span> </span> </div> </div> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Electrochemical Response Transductions of Graphenated-Polyaniline Nanosensor for Environmental Anthracene</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=O.%20Tovide">O. Tovide</a>, <a href="https://publications.waset.org/search?q=N.%20Jahed"> N. Jahed</a>, <a href="https://publications.waset.org/search?q=N.%20Mohammed"> N. Mohammed</a>, <a href="https://publications.waset.org/search?q=C.%20E.%20Sunday"> C. E. Sunday</a>, <a href="https://publications.waset.org/search?q=H.%20R.%20Makelane"> H. R. Makelane</a>, <a href="https://publications.waset.org/search?q=R.%20F.%20Ajayi"> R. F. Ajayi</a>, <a href="https://publications.waset.org/search?q=K.%20M.%20Molapo"> K. M. Molapo</a>, <a href="https://publications.waset.org/search?q=A.%20Tsegaye"> A. Tsegaye</a>, <a href="https://publications.waset.org/search?q=M.%20Masikini"> M. Masikini</a>, <a href="https://publications.waset.org/search?q=S.%20Mailu"> S. Mailu</a>, <a href="https://publications.waset.org/search?q=A.%20Baleg"> A. Baleg</a>, <a href="https://publications.waset.org/search?q=T.%20Waryo"> T. Waryo</a>, <a href="https://publications.waset.org/search?q=P.%20G.%20Baker"> P. G. Baker</a>, <a href="https://publications.waset.org/search?q=E.%20I.%20Iwuoha"> E. I. Iwuoha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A graphenated–polyaniline (GR-PANI) nanocomposite sensor was constructed and used for the determination of anthracene. The direct electro-oxidation behavior of anthracene on the GR-PANI modified glassy carbon electrode (GCE) was used as the sensing principle. The results indicate thatthe response profile of the oxidation of anthracene on GR-PANI-modified GCE provides for the construction of sensor systems based onamperometric and potentiometric signal transductions. A dynamic linear range of 0.12- 100 µM anthracene and a detection limit of 0.044 µM anthracene were established for the sensor system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Electrochemical%20sensors" title="Electrochemical sensors">Electrochemical sensors</a>, <a href="https://publications.waset.org/search?q=environmental%20pollutants" title=" environmental pollutants"> environmental pollutants</a>, <a href="https://publications.waset.org/search?q=graphenated-polymers" title=" graphenated-polymers"> graphenated-polymers</a>, <a href="https://publications.waset.org/search?q=polyaromatic%20hydrocarbon." title=" polyaromatic hydrocarbon."> polyaromatic hydrocarbon.</a> </p> <a href="https://publications.waset.org/10010894/electrochemical-response-transductions-of-graphenated-polyaniline-nanosensor-for-environmental-anthracene" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/10010894/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/10010894/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/10010894/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/10010894/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/10010894/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/10010894/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/10010894/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/10010894/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/10010894/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/10010894/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/10010894.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">751</span> </span> </div> </div> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> A Nanosensor System Based On Disuccinimydyl鈥揅YP2E1 for Amperometric Detection of the Anti-Tuberculosis Drug, Pyrazinamide</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=R.%20F.%20Ajayi">R. F. Ajayi</a>, <a href="https://publications.waset.org/search?q=U.%20Sidwaba"> U. Sidwaba</a>, <a href="https://publications.waset.org/search?q=U.%20Feleni"> U. Feleni</a>, <a href="https://publications.waset.org/search?q=S.%20F.%20Douman"> S. F. Douman</a>, <a href="https://publications.waset.org/search?q=E.%20Nxusani"> E. Nxusani</a>, <a href="https://publications.waset.org/search?q=L.%20Wilson"> L. Wilson</a>, <a href="https://publications.waset.org/search?q=C.%20Rassie"> C. Rassie</a>, <a href="https://publications.waset.org/search?q=O.%20Tovide"> O. Tovide</a>, <a href="https://publications.waset.org/search?q=P.%20G.%20L.%20Baker"> P. G. L. Baker</a>, <a href="https://publications.waset.org/search?q=S.%20L.%20%20Vilakazi"> S. L. Vilakazi</a>, <a href="https://publications.waset.org/search?q=R.%20Tshikhudo"> R. Tshikhudo</a>, <a href="https://publications.waset.org/search?q=E.%20I.%20Iwuoha"> E. I. Iwuoha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>Pyrazinamide (PZA) is among the first-line pro-drugs in the tuberculosis (TB) combination chemotherapy used to treat Mycobacterium tuberculosis. Numerous reports have suggested that hepatotoxicity due to pyrazinamide in patients is due to inappropriate dosing. It is, therefore necessary to develop sensitive and reliable techniques for determining the PZA metabolic profile of diagnosed patients promptly and at point-of-care. This study reports the determination of PZA based on nanobiosensor systems developed from disuccinimidyl octanedioate modified Cytochrome P450-2E1 (CYP2E1) electrodeposited on gold substrates derivatised with (poly(8-anilino-1-napthalene sulphonic acid) PANSA/PVP-AgNPs nanocomposites. The rapid and sensitive amperometric PZA detection gave a dynamic linear range of 2µM to 16µM revealing a limit of detection of 0.044µM and a sensitivity of 1.38µA/µM. The Michaelis-Menten parameters; KM, KM app and IMAX were calculated to be 6.0µM, 1.41µM and 1.51x10-6 A, respectively, indicating a nanobiosensor suitable for use in serum.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Cytochrome%20P450-2E1" title="Cytochrome P450-2E1">Cytochrome P450-2E1</a>, <a href="https://publications.waset.org/search?q=Disuccinimidyl%20%0D%0Aoctanedioate" title=" Disuccinimidyl octanedioate"> Disuccinimidyl octanedioate</a>, <a href="https://publications.waset.org/search?q=Pyrazinamide" title=" Pyrazinamide"> Pyrazinamide</a>, <a href="https://publications.waset.org/search?q=Tuberculosis." title=" Tuberculosis."> Tuberculosis.</a> </p> <a href="https://publications.waset.org/9997308/a-nanosensor-system-based-on-disuccinimydyl-cyp2e1-for-amperometric-detection-of-the-anti-tuberculosis-drug-pyrazinamide" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/9997308/apa" 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