Search results for: Shasline Gedeon

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Gedeon</title> <meta name="description" content="Search results for: Shasline Gedeon"> <meta name="keywords" content="Shasline Gedeon"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Shasline Gedeon"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 3</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Shasline Gedeon</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> A Photoredox (C)sp鲁-(C)sp虏 Coupling Method Comparison Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shasline%20Gedeon">Shasline Gedeon</a>, <a href="https://publications.waset.org/abstracts/search?q=Tiffany%20W.%20Ardley"> Tiffany W. Ardley</a>, <a href="https://publications.waset.org/abstracts/search?q=Ying%20Wang"> Ying Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Nathan%20J.%20Gesmundo"> Nathan J. Gesmundo</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20A.%20Sarris"> Katarina A. Sarris</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20L.%20Aguirre"> Ana L. Aguirre</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Drug discovery and delivery involve drug targeting, an approach that helps find a drug against a chosen target through high throughput screening and other methods by way of identifying the physical properties of the potential lead compound. Physical properties of potential drug candidates have been an imperative focus since the unveiling of Lipinski's Rule of 5 for oral drugs. Throughout a compound's journey from discovery, clinical phase trials, then becoming a classified drug on the market, the desirable properties are optimized while minimizing/eliminating toxicity and undesirable properties. In the pharmaceutical industry, the ability to generate molecules in parallel with maximum efficiency is a substantial factor achieved through sp虏-sp虏 carbon coupling reactions, e.g., Suzuki Coupling reactions. These reaction types allow for the increase of aromatic fragments onto a compound. More recent literature has found benefits to decreasing aromaticity, calling for more sp鲁-sp虏 carbon coupling reactions instead. The objective of this project is to provide a comparison between various sp鲁-sp虏 carbon coupling methods and reaction conditions, collecting data on production of the desired product. There were four different coupling methods being tested amongst three cores and 4-5 installation groups per method; each method ran under three distinct reaction conditions. The tested methods include the Photoredox Decarboxylative Coupling, the Photoredox Potassium Alkyl Trifluoroborate (BF3K) Coupling, the Photoredox Cross-Electrophile (PCE) Coupling, and the Weix Cross-Electrophile (WCE) Coupling. The results concluded that the Decarboxylative method was very difficult in yielding product despite the several literature conditions chosen. The BF3K and PCE methods produced competitive results. Amongst the two Cross-Electrophile coupling methods, the Photoredox method surpassed the Weix method on numerous accounts. The results will be used to build future libraries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drug%20discovery" title="drug discovery">drug discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=high%20throughput%20chemistry" title=" high throughput chemistry"> high throughput chemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=photoredox%20chemistry" title=" photoredox chemistry"> photoredox chemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=sp%C2%B3-sp%C2%B2%20carbon%20coupling%20methods" title=" sp鲁-sp虏 carbon coupling methods"> sp鲁-sp虏 carbon coupling methods</a> </p> <a href="https://publications.waset.org/abstracts/122791/a-photoredox-csp3-csp2-coupling-method-comparison-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/122791.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">144</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Popular eReaders</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tom%20D.%20Gedeon">Tom D. Gedeon</a>, <a href="https://publications.waset.org/abstracts/search?q=Ujala%20Rampaul"> Ujala Rampaul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The evaluation of electronic consumer goods are most often done from the perspective of analysing the latest models, comparing their advantages and disadvantages with respect to price. This style of evaluation is often performed by one or a few product experts on a wide range of features that may not be applicable to each user. We instead used a scenario-based approach to evaluate a number of e-readers. The setting is similar to a user who is interested in a new product or technology and has allocated a limited budget. We evaluate the quality and usability of e-readers available within that budget range. This is based on the assumption of a rational market which prices older second hand devices the same as functionally equivalent new devices. We describe our evaluation and comparison of four branded eReaders, as the initial stage of a larger project. The scenario has a range of tasks approximating a busy person who does not bother to read the manual. We found that navigation within books to be the most significant differentiator between the eReaders in our scenario based evaluation process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=eReader" title="eReader">eReader</a>, <a href="https://publications.waset.org/abstracts/search?q=scenario%20based" title=" scenario based"> scenario based</a>, <a href="https://publications.waset.org/abstracts/search?q=price%20comparison" title=" price comparison"> price comparison</a>, <a href="https://publications.waset.org/abstracts/search?q=Kindle" title=" Kindle"> Kindle</a>, <a href="https://publications.waset.org/abstracts/search?q=Kobo" title=" Kobo"> Kobo</a>, <a href="https://publications.waset.org/abstracts/search?q=Nook" title=" Nook"> Nook</a>, <a href="https://publications.waset.org/abstracts/search?q=Sony" title=" Sony"> Sony</a>, <a href="https://publications.waset.org/abstracts/search?q=technology%20adoption" title=" technology adoption"> technology adoption</a> </p> <a href="https://publications.waset.org/abstracts/29543/popular-ereaders" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29543.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">530</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> South African Multiple Deprivation-Concentration Index Quantiles Differentiated by Components of Success and Impediment to Tuberculosis Control Programme Using Mathematical Modelling in Rural O. R. Tambo District Health Facilities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ntandazo%20Dlatu">Ntandazo Dlatu</a>, <a href="https://publications.waset.org/abstracts/search?q=Benjamin%20Longo-Mbenza"> Benjamin Longo-Mbenza</a>, <a href="https://publications.waset.org/abstracts/search?q=Andre%20Renzaho"> Andre Renzaho</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruffin%20Appalata"> Ruffin Appalata</a>, <a href="https://publications.waset.org/abstracts/search?q=Yolande%20Yvonne%20Valeria%20Matoumona%20Mavoungou"> Yolande Yvonne Valeria Matoumona Mavoungou</a>, <a href="https://publications.waset.org/abstracts/search?q=Mbenza%20Ben%20Longo"> Mbenza Ben Longo</a>, <a href="https://publications.waset.org/abstracts/search?q=Kenneth%20Ekoru"> Kenneth Ekoru</a>, <a href="https://publications.waset.org/abstracts/search?q=Blaise%20Makoso"> Blaise Makoso</a>, <a href="https://publications.waset.org/abstracts/search?q=Gedeon%20Longo%20Longo"> Gedeon Longo Longo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The gap between complexities related to the integration of Tuberculosis /HIV control and evidence-based knowledge motivated the initiation of the study. Therefore, the objective of this study was to explore correlations between national TB management guidelines, multiple deprivation indexes, quantiles, components and levels of Tuberculosis control programme using mathematical modeling in rural O.R. Tambo District Health Facilities, South Africa. Methods: The study design used mixed secondary data analysis and cross-sectional analysis between 2009 and 2013 across O.R Tambo District, Eastern Cape, South Africa using univariate/ bivariate analysis, linear multiple regression models, and multivariate discriminant analysis. Health inequalities indicators and component of an impediment to the tuberculosis control programme were evaluated. Results: In total, 62 400 records for TB notification were analyzed for the period 2009-2013. There was a significant but negative between Financial Year Expenditure (r= -0.894; P= 0.041) Seropositive HIV status(r= -0.979; P= 0.004), Population Density (r = -0.881; P= 0.048) and the number of TB defaulter in all TB cases. It was shown unsuccessful control of TB management program through correlations between numbers of new PTB smear positive, TB defaulter new smear-positive, TB failure all TB, Pulmonary Tuberculosis case finding index and deprivation-concentration-dispersion index. It was shown successful TB program control through significant and negative associations between declining numbers of death in co-infection of HIV and TB, TB deaths all TB and SMIAD gradient/ deprivation-concentration-dispersion index. The multivariate linear model was summarized by unadjusted r of 96%, adjusted R2 of 95 %, Standard Error of estimate of 0.110, R2 changed of 0.959 and significance for variance change for P=0.004 to explain the prediction of TB defaulter in all TB with equation y= 8.558-0.979 x number of HIV seropositive. After adjusting for confounding factors (PTB case finding the index, TB defaulter new smear-positive, TB death in all TB, TB defaulter all TB, and TB failure in all TB). The HIV and TB death, as well as new PTB smear positive, were identified as the most important, significant, and independent indicator to discriminate most deprived deprivation index far from other deprivation quintiles 2-5 using discriminant analysis. Conclusion: Elimination of poverty such as overcrowding, lack of sanitation and environment of highest burden of HIV might end the TB threat in O.R Tambo District, Eastern Cape, South Africa. Furthermore, ongoing adequate budget comprehensive, holistic and collaborative initiative towards Sustainable Developmental Goals (SDGs) is necessary for complete elimination of TB in poor O.R Tambo District. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title="tuberculosis">tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=HIV%2FAIDS" title=" HIV/AIDS"> HIV/AIDS</a>, <a href="https://publications.waset.org/abstracts/search?q=success" title=" success"> success</a>, <a href="https://publications.waset.org/abstracts/search?q=failure" title=" failure"> failure</a>, <a href="https://publications.waset.org/abstracts/search?q=control%20program" title=" control program"> control program</a>, <a href="https://publications.waset.org/abstracts/search?q=health%20inequalities" title=" health inequalities"> health inequalities</a>, <a href="https://publications.waset.org/abstracts/search?q=South%20Africa" title=" South Africa"> South Africa</a> </p> <a href="https://publications.waset.org/abstracts/91487/south-african-multiple-deprivation-concentration-index-quantiles-differentiated-by-components-of-success-and-impediment-to-tuberculosis-control-programme-using-mathematical-modelling-in-rural-o-r-tambo-district-health-facilities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91487.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">170</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a 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Search results for: Shasline Gedeon