Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals

<!DOCTYPE html> <html class="no-js" dir="ltr" lang="en-US" prefix="og: http://ogp.me/ns# fb: http://ogp.me/ns/fb#"> <head> <meta charset="utf-8"> <meta http-equiv="x-ua-compatible" content="ie=edge"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <title>Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals | PharmaVoice</title> <meta name="description" content="News for pharmacy pros"/> <meta name="sailthru.tags" content="pharmavoice,type-newspost,pharmavoice-pharma,pharmavoice-research-development,pharmavoice-tag-cancer"/> <meta property="fb:pages" content="212905108768849"> <script data-cfasync="false"> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('consent','default',{ 'ad_storage':'denied', 'analytics_storage':'denied', 'ad_user_data':'denied', 'ad_personalization':'denied', 'personalization_storage':'denied', 'functionality_storage':'granted', 'security_storage':'granted', 'wait_for_update': 500 }); gtag("set", "ads_data_redaction", true); </script> <script data-cfasync="false" src="https://cmp.osano.com/AzqdtLT8Mqkut2TZ/bdeb2f70-056f-4937-961a-e9db412e4c7a/osano.js"></script> <style> .osano-cm-widget{display: none;} </style> <script data-cfasync="false"> window.Osano.cm.addEventListener("osano-cm-script-blocked", function (item) { console.log("Script blocked: " + item); }); window.Osano.cm.addEventListener("osano-cm-cookie-blocked", function (item) { console.log("Cookie blocked: " + item); }); </script> <script> window.dive_location = "NonEU"; window.dive_limit_data_processing = false; </script>  <link rel="icon" type="image/x-icon" sizes="any" href="/favicon.ico?v=2" /> <link rel="apple-touch-icon" sizes="180x180" href="/apple-touch-icon.png?v=2"> <link rel="icon" type="image/png" sizes="32x32" href="/favicon-32x32.png?v=2"> <link rel="icon" type="image/png" sizes="16x16" href="/favicon-16x16.png?v=2"> <link rel="manifest" href="/site.webmanifest?v=2"> <link rel="mask-icon" href="/safari-pinned-tab.svg?v=2" color="#5bbad5"> <meta name="msapplication-TileImage" content="/mstile-150x150.png?v=2"> <meta name="msapplication-TileColor" content="#603cba"> <meta name="theme-color" content="#ffffff"> <link rel="alternate" type="application/rss+xml" title="PharmaVoice - Latest News Feed" href="https://www.pharmavoice.com/feeds/news/"/> <link rel="canonical" href="https://www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"/> <meta name="title" content="Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals" /> <meta name="medium" content="news" /> <meta name="date" content="2024-11-21" /> <meta name="twitter:card" content="summary_large_image"> <meta name="twitter:domain" content="PharmaVoice"> <meta name="twitter:site" content="@PharmaVoice"> <meta property="og:title" name="og:title" content="Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals" /> <meta property="og:site_name" name="og:site_name" content="PharmaVoice" /> <meta property="og:type" name="og:type" content="article" /> <meta name="article_date_original" content="Thursday, November 21, 2024, 07:12 AM" /> <meta property="og:url" name="og:url" content="https://www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" /> <meta property="og:image" name="og:image" content="https://imgproxy.divecdn.com/Mo4LHwDBwt4bdhZ1fBMKeswWOFHgT8mWjT44xw50-WE/g:ce/rs:fit:770:435/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" /> <meta property="og:description" name="og:description" content="A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market." /> <meta name="sailthru.date" content="2024-11-21T07:12:57" /> <meta name="sailthru.expire_date" content="2034-11-09T07:12:57" /> <meta name="sailthru.author" content="Michael Gibney" /> <meta name="sailthru.image.full" content="https://imgproxy.divecdn.com/Mo4LHwDBwt4bdhZ1fBMKeswWOFHgT8mWjT44xw50-WE/g:ce/rs:fit:770:435/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" />  <meta name="sailthru.image.thumb" content="https://imgproxy.divecdn.com/v4MabBWQ5WUcj-Moee7U1NKQJUIsdQgU3xICt9NOeeU/g:ce/rs:fit:106:60/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" />  <meta name="sailthru.description" content="A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market." /> <link rel="stylesheet" href="/static/css/pharmavoice_app.css?330116211124"> <script> // Initialize dataLayer empty array for GTM events window.dataLayer = window.dataLayer || []; window.dataLayer.push({ 'site': 'PharmaVoice', }); // wrapper function to push GTM events to dataLayer pushGTMEvent = (eventObject) => { // if window.datalayer is not defined, then set to an empty array window.dataLayer.push(eventObject); }; </script>  <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-55G8WRR');</script>  <script> let eventParams = {}; eventParams.author = "Michael Gibney"; eventParams.date_published_readable = "2024-11-21"; eventParams.post_type = "Article"; eventParams.tags = "Cancer"; eventParams.topics = "Pharma, Research & Development"; eventParams.clone = "False"; const gtmEventObject = { event: 'page.content', 'page.content': { v:11, // seer version ...eventParams } }; window.pushGTMEvent(gtmEventObject); </script> <script type="module" src="/static/js/dist/lyticsHelper.bundle.js?520216211124" ></script> <script type="text/javascript" src="/static/js/ad_blocker_recovery.js?160016291122"></script>  <script async src="https://fundingchoicesmessages.google.com/i/pub-8553262192892817?ers=1" nonce="RORABhIXgMhQdZXbks8fZQ"></script> <script nonce="RORABhIXgMhQdZXbks8fZQ">(function() {function signalGooglefcPresent() {if (!window.frames['googlefcPresent']) {if (document.body) {const iframe = document.createElement('iframe'); iframe.style = 'width: 0; height: 0; border: none; z-index: -1000; left: -1000px; top: -1000px;'; iframe.style.display = 'none'; iframe.name = 'googlefcPresent'; document.body.appendChild(iframe);} else {setTimeout(signalGooglefcPresent, 0);}}}signalGooglefcPresent();})();</script>  <script>(function(){/* Copyright The Closure Library Authors. SPDX-License-Identifier: Apache-2.0 */ 'use strict';var aa=function(a){var b=0;return function(){return b<a.length?{done:!1,value:a[b++]}:{done:!0}}},ba="function"==typeof Object.create?Object.create:function(a){var b=function(){};b.prototype=a;return new b},k;if("function"==typeof Object.setPrototypeOf)k=Object.setPrototypeOf;else{var m;a:{var ca={a:!0},n={};try{n.__proto__=ca;m=n.a;break a}catch(a){}m=!1}k=m?function(a,b){a.__proto__=b;if(a.__proto__!==b)throw new TypeError(a+" is not extensible");return a}:null} var p=k,q=function(a,b){a.prototype=ba(b.prototype);a.prototype.constructor=a;if(p)p(a,b);else for(var c in b)if("prototype"!=c)if(Object.defineProperties){var d=Object.getOwnPropertyDescriptor(b,c);d&&Object.defineProperty(a,c,d)}else a[c]=b[c];a.v=b.prototype},r=this||self,da=function(){},t=function(a){return a};var u;var w=function(a,b){this.g=b===v?a:""};w.prototype.toString=function(){return this.g+""};var v={},x=function(a){if(void 0===u){var b=null;var c=r.trustedTypes;if(c&&c.createPolicy){try{b=c.createPolicy("goog#html",{createHTML:t,createScript:t,createScriptURL:t})}catch(d){r.console&&r.console.error(d.message)}u=b}else u=b}a=(b=u)?b.createScriptURL(a):a;return new w(a,v)};var A=function(){return Math.floor(2147483648*Math.random()).toString(36)+Math.abs(Math.floor(2147483648*Math.random())^Date.now()).toString(36)};var B={},C=null;var D="function"===typeof Uint8Array;function E(a,b,c){return"object"===typeof a?D&&!Array.isArray(a)&&a instanceof Uint8Array?c(a):F(a,b,c):b(a)}function F(a,b,c){if(Array.isArray(a)){for(var d=Array(a.length),e=0;e<a.length;e++){var f=a[e];null!=f&&(d[e]=E(f,b,c))}Array.isArray(a)&&a.s&&G(d);return d}d={};for(e in a)Object.prototype.hasOwnProperty.call(a,e)&&(f=a[e],null!=f&&(d[e]=E(f,b,c)));return d} function ea(a){return F(a,function(b){return"number"===typeof b?isFinite(b)?b:String(b):b},function(b){var c;void 0===c&&(c=0);if(!C){C={};for(var d="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789".split(""),e=["+/=","+/","-_=","-_.","-_"],f=0;5>f;f++){var h=d.concat(e[f].split(""));B[f]=h;for(var g=0;g<h.length;g++){var l=h[g];void 0===C[l]&&(C[l]=g)}}}c=B[c];d=Array(Math.floor(b.length/3));e=c[64]||"";for(f=h=0;h<b.length-2;h+=3){var y=b[h],z=b[h+1];l=b[h+2];g=c[y>>2];y=c[(y&3)<< 4|z>>4];z=c[(z&15)<<2|l>>6];l=c[l&63];d[f++]=""+g+y+z+l}g=0;l=e;switch(b.length-h){case 2:g=b[h+1],l=c[(g&15)<<2]||e;case 1:b=b[h],d[f]=""+c[b>>2]+c[(b&3)<<4|g>>4]+l+e}return d.join("")})}var fa={s:{value:!0,configurable:!0}},G=function(a){Array.isArray(a)&&!Object.isFrozen(a)&&Object.defineProperties(a,fa);return a};var H;var J=function(a,b,c){var d=H;H=null;a||(a=d);d=this.constructor.u;a||(a=d?[d]:[]);this.j=d?0:-1;this.h=null;this.g=a;a:{d=this.g.length;a=d-1;if(d&&(d=this.g[a],!(null===d||"object"!=typeof d||Array.isArray(d)||D&&d instanceof Uint8Array))){this.l=a-this.j;this.i=d;break a}void 0!==b&&-1<b?(this.l=Math.max(b,a+1-this.j),this.i=null):this.l=Number.MAX_VALUE}if(c)for(b=0;b<c.length;b++)a=c[b],a<this.l?(a+=this.j,(d=this.g[a])?G(d):this.g[a]=I):(d=this.l+this.j,this.g[d]||(this.i=this.g[d]={}),(d=this.i[a])? G(d):this.i[a]=I)},I=Object.freeze(G([])),K=function(a,b){if(-1===b)return null;if(b<a.l){b+=a.j;var c=a.g[b];return c!==I?c:a.g[b]=G([])}if(a.i)return c=a.i[b],c!==I?c:a.i[b]=G([])},M=function(a,b){var c=L;if(-1===b)return null;a.h||(a.h={});if(!a.h[b]){var d=K(a,b);d&&(a.h[b]=new c(d))}return a.h[b]};J.prototype.toJSON=function(){var a=N(this,!1);return ea(a)}; var N=function(a,b){if(a.h)for(var c in a.h)if(Object.prototype.hasOwnProperty.call(a.h,c)){var d=a.h[c];if(Array.isArray(d))for(var e=0;e<d.length;e++)d[e]&&N(d[e],b);else d&&N(d,b)}return a.g},O=function(a,b){H=b=b?JSON.parse(b):null;a=new a(b);H=null;return a};J.prototype.toString=function(){return N(this,!1).toString()};var P=function(a){J.call(this,a)};q(P,J);function ha(a){var b,c=(a.ownerDocument&&a.ownerDocument.defaultView||window).document,d=null===(b=c.querySelector)||void 0===b?void 0:b.call(c,"script[nonce]");(b=d?d.nonce||d.getAttribute("nonce")||"":"")&&a.setAttribute("nonce",b)};var Q=function(a,b){b=String(b);"application/xhtml+xml"===a.contentType&&(b=b.toLowerCase());return a.createElement(b)},R=function(a){this.g=a||r.document||document};R.prototype.appendChild=function(a,b){a.appendChild(b)};var S=function(a,b,c,d,e,f){try{var h=a.g,g=Q(a.g,"SCRIPT");g.async=!0;g.src=b instanceof w&&b.constructor===w?b.g:"type_error:TrustedResourceUrl";ha(g);h.head.appendChild(g);g.addEventListener("load",function(){e();d&&h.head.removeChild(g)});g.addEventListener("error",function(){0<c?S(a,b,c-1,d,e,f):(d&&h.head.removeChild(g),f())})}catch(l){f()}};var ia=r.atob("aHR0cHM6Ly93d3cuZ3N0YXRpYy5jb20vaW1hZ2VzL2ljb25zL21hdGVyaWFsL3N5c3RlbS8xeC93YXJuaW5nX2FtYmVyXzI0ZHAucG5n"),ja=r.atob("WW91IGFyZSBzZWVpbmcgdGhpcyBtZXNzYWdlIGJlY2F1c2UgYWQgb3Igc2NyaXB0IGJsb2NraW5nIHNvZnR3YXJlIGlzIGludGVyZmVyaW5nIHdpdGggdGhpcyBwYWdlLg=="),ka=r.atob("RGlzYWJsZSBhbnkgYWQgb3Igc2NyaXB0IGJsb2NraW5nIHNvZnR3YXJlLCB0aGVuIHJlbG9hZCB0aGlzIHBhZ2Uu"),la=function(a,b,c){this.h=a;this.j=new R(this.h);this.g=null;this.i=[];this.l=!1;this.o=b;this.m=c},V=function(a){if(a.h.body&&!a.l){var b= function(){T(a);r.setTimeout(function(){return U(a,3)},50)};S(a.j,a.o,2,!0,function(){r[a.m]||b()},b);a.l=!0}},T=function(a){for(var b=W(1,5),c=0;c<b;c++){var d=X(a);a.h.body.appendChild(d);a.i.push(d)}b=X(a);b.style.bottom="0";b.style.left="0";b.style.position="fixed";b.style.width=W(100,110).toString()+"%";b.style.zIndex=W(2147483544,2147483644).toString();b.style["background-color"]=ma(249,259,242,252,219,229);b.style["box-shadow"]="0 0 12px #888";b.style.color=ma(0,10,0,10,0,10);b.style.display= "flex";b.style["justify-content"]="center";b.style["font-family"]="Roboto, Arial";c=X(a);c.style.width=W(80,85).toString()+"%";c.style.maxWidth=W(750,775).toString()+"px";c.style.margin="24px";c.style.display="flex";c.style["align-items"]="flex-start";c.style["justify-content"]="center";d=Q(a.j.g,"IMG");d.className=A();d.src=ia;d.style.height="24px";d.style.width="24px";d.style["padding-right"]="16px";var e=X(a),f=X(a);f.style["font-weight"]="bold";f.textContent=ja;var h=X(a);h.textContent=ka;Y(a, e,f);Y(a,e,h);Y(a,c,d);Y(a,c,e);Y(a,b,c);a.g=b;a.h.body.appendChild(a.g);b=W(1,5);for(c=0;c<b;c++)d=X(a),a.h.body.appendChild(d),a.i.push(d)},Y=function(a,b,c){for(var d=W(1,5),e=0;e<d;e++){var f=X(a);b.appendChild(f)}b.appendChild(c);c=W(1,5);for(d=0;d<c;d++)e=X(a),b.appendChild(e)},W=function(a,b){return Math.floor(a+Math.random()*(b-a))},ma=function(a,b,c,d,e,f){return"rgb("+W(Math.max(a,0),Math.min(b,255)).toString()+","+W(Math.max(c,0),Math.min(d,255)).toString()+","+W(Math.max(e,0),Math.min(f, 255)).toString()+")"},X=function(a){a=Q(a.j.g,"DIV");a.className=A();return a},U=function(a,b){0>=b||null!=a.g&&0!=a.g.offsetHeight&&0!=a.g.offsetWidth||(na(a),T(a),r.setTimeout(function(){return U(a,b-1)},50))},na=function(a){var b=a.i;var c="undefined"!=typeof Symbol&&Symbol.iterator&&b[Symbol.iterator];b=c?c.call(b):{next:aa(b)};for(c=b.next();!c.done;c=b.next())(c=c.value)&&c.parentNode&&c.parentNode.removeChild(c);a.i=[];(b=a.g)&&b.parentNode&&b.parentNode.removeChild(b);a.g=null};var pa=function(a,b,c,d,e){var f=oa(c),h=function(l){l.appendChild(f);r.setTimeout(function(){f?(0!==f.offsetHeight&&0!==f.offsetWidth?b():a(),f.parentNode&&f.parentNode.removeChild(f)):a()},d)},g=function(l){document.body?h(document.body):0<l?r.setTimeout(function(){g(l-1)},e):b()};g(3)},oa=function(a){var b=document.createElement("div");b.className=a;b.style.width="1px";b.style.height="1px";b.style.position="absolute";b.style.left="-10000px";b.style.top="-10000px";b.style.zIndex="-10000";return b};var L=function(a){J.call(this,a)};q(L,J);var qa=function(a){J.call(this,a)};q(qa,J);var ra=function(a,b){this.l=a;this.m=new R(a.document);this.g=b;this.i=K(this.g,1);b=M(this.g,2);this.o=x(K(b,4)||"");this.h=!1;b=M(this.g,13);b=x(K(b,4)||"");this.j=new la(a.document,b,K(this.g,12))};ra.prototype.start=function(){sa(this)}; var sa=function(a){ta(a);S(a.m,a.o,3,!1,function(){a:{var b=a.i;var c=r.btoa(b);if(c=r[c]){try{var d=O(P,r.atob(c))}catch(e){b=!1;break a}b=b===K(d,1)}else b=!1}b?Z(a,K(a.g,14)):(Z(a,K(a.g,8)),V(a.j))},function(){pa(function(){Z(a,K(a.g,7));V(a.j)},function(){return Z(a,K(a.g,6))},K(a.g,9),K(a.g,10),K(a.g,11))})},Z=function(a,b){a.h||(a.h=!0,a=new a.l.XMLHttpRequest,a.open("GET",b,!0),a.send())},ta=function(a){var b=r.btoa(a.i);a.l[b]&&Z(a,K(a.g,5))};(function(a,b){r[a]=function(c){for(var d=[],e=0;e<arguments.length;++e)d[e-0]=arguments[e];r[a]=da;b.apply(null,d)}})("__h82AlnkH6D91__",function(a){"function"===typeof window.atob&&(new ra(window,O(qa,window.atob(a)))).start()});}).call(this); window.__h82AlnkH6D91__("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"); </script> <script src="/static/js/jquery_360.min.js?543516150322"></script> <script> // waitForTriggerHandler() is library for queuing up javascript to be stored and then executed when a trigger // function is called. You can push() any number of functions which will be stored unless and until trigger() // is called. Once trigger() is called any future functions that you push() in will be executed immediately. // It is safe to call .trigger() multiple times. Any arguments passed to .trigger() will also be passed along // to the associated function function waitForTriggerHandler() { var function_queue = []; var trigger_arguments = []; this._triggered = false; this.push = function(fn) { if (this._triggered) { // just run it immediately if handler has already been triggered fn.apply(null, trigger_arguments); } else { // otherwise add to the queue to run later function_queue.push(fn); } }; this.trigger = function() { // any arguments passed to trigger(foo, bar, baz) will also be passed along to functions in the queue // first convert any arguments to an array trigger_arguments = Array.prototype.slice.call(arguments); while (function_queue.length){ // for each function in the queue, pop it off and then execute it while passing in any // args that may have been passed to trigger(). function_queue.pop().apply(null, trigger_arguments); // The "null" above is for the value of "this". // See https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/Function/apply#Parameters } this._triggered = true; } } // set up waitToLoadAds handler window.waitToLoadAds = new waitForTriggerHandler(); // We set up the triggers for this below, they depend on whether we're loading lytics on the page </script> <script type="text/javascript"> // This token is here for test_lytics_snippet.py test: lytics-is-enabled window.googletag = window.googletag || {}; googletag.cmd = googletag.cmd || []; // initialize callback (source: https://learn.lytics.com/product-docs/lytics-javascript-tag/receiving-data-from-lytics) !function(){"use strict";var o=window.jstag||(window.jstag={}),r=[];function n(e){o[e]=function(){for(var n=arguments.length,t=new Array(n),i=0;i<n;i++)t[i]=arguments[i];r.push([e,t])}}n("send"),n("mock"),n("identify"),n("pageView"),n("unblock"),n("getid"),n("setid"),n("loadEntity"),n("getEntity"),n("on"),n("once"),n("call"),o.loadScript=function(n,t,i){var e=document.createElement("script");e.async=!0,e.src=n,e.onload=t,e.onerror=i;var o=document.getElementsByTagName("script")[0],r=o&&o.parentNode||document.head||document.body,c=o||r.lastChild;return null!=c?r.insertBefore(e,c):r.appendChild(e),this},o.init=function n(t){return this.config=t,this.loadScript(t.src,function(){if(o.init===n)throw new Error("Load error!");o.init(o.config),function(){for(var n=0;n<r.length;n++){var t=r[n][0],i=r[n][1];o[t].apply(o,i)}r=void 0}()}),this}}(); // custom init + lytics default install tag from https://activate.getlytics.com/connect?aid=2751 // see https://learn.lytics.com/understanding/product-docs/lytics-javascript-tag/configuration#configuration-options var lyticsCid = '44fda7674f94228540d8fba6786f9770'; console.log('You are using the Lytics Prod account'); jstag.init({ src: `https://c.lytics.io/api/tag/${lyticsCid}/latest.min.js`, pageAnalysis: { dataLayerPull: { disabled: true } } }); jstag.pageView(); (function(){ var sailthru_cookie, sailthru_user_id; function read_cookie(cookieName) { var re = new RegExp('[; ]'+cookieName+'=([^\\s;]*)'); var sMatch = (' '+document.cookie).match(re); if (cookieName && sMatch) return unescape(sMatch[1]); return ''; } sailthru_cookie = read_cookie('sailthru_hid'); if (sailthru_cookie.length > 56) { sailthru_user_id = sailthru_cookie.slice(32,56); jstag.send({ st_profile_id: sailthru_user_id }); } })(); jstag.call('entityReady', waitToLoadAds.trigger); setTimeout(waitToLoadAds.trigger, 1000); // also trigger lytics if it's taking too long waitToLoadAds.push(function (lytics_data) { // lytics_data won't be defined if lytics failed to load correctly. In that case // we don't need to set any segments. if (lytics_data && lytics_data.segments) { googletag.cmd.push(function() { googletag.pubads().setTargeting("LyticsSegments", lytics_data.segments); }); } }); function getUID(id) { window.dataLayer.push({'user_id': id}); }; jstag.getid(getUID); </script> <script type="text/javascript" src="/static/js/mailcheck.min.js?192616240919"></script> <script type="text/javascript" src="/static/js/dive_mailcheck.js?192616240919"></script> <script src="/static/js/app.js?040116120224"></script> <script type="text/javascript"> var divecounter_settings = {}; divecounter_settings.showSignupAd = true; </script> <script type="text/javascript" src="/static/js/divecounter.js?261616040423"></script> <script type="text/javascript"> // Special unbounce signup thing for google traffic. Test with ?test_unbounce in the URL // Note: divecounter must already be loaded. Only enabled on pages that would normally have signup ads // Note: showSignupAd is always off if prestitial is enabled! if ((typeof divecounter !== "undefined") && ($(window).width() > 640)) { var test_unbounce = (window.location.href.indexOf("?test_unbounce")>=0); var force_unbounce = (window.location.href.indexOf("signupbounce=1")>=0) || (window.location.href.indexOf("utm_campaign=Linked-HR")>=0) || (window.location.href.indexOf("utm_source=outbrain")>=0); if (test_unbounce || force_unbounce || (document.referrer.match(/^https?:\/\/(www\.google\.|news\.google\.|t\.co|twitter\.com|www\.facebook\.com)/i) && divecounter.getOption('showSignupAd') && divecounter.canShow(1,1)) ) { // dyanmically load ouibounce.js only on pages where its needed $.getScript("/static/js/ouibounce.min.js?102717100918", function(){ // Once ouibounce.js loads, call the script // We're reusing divecounter's modal instead of OuiBounce's modal code (that's why we pass it 'false') var _ouibounce = ouibounce(false, { aggressive: test_unbounce, // ignore cookie in test mode cookieName: '_viewedOuiBounce', // underscored cookies should be ignored by Varnish callback: function() { divecounter_open_ad(); } }); }); } // end should show unbounce } // end divecounter defined </script> <script type="text/javascript"> // Load analytics.js (universal analytics) first (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','//www.google-analytics.com/analytics.js','ga'); // set all the variables that are per-session or per-visit ga( 'create', 'UA-19684343-71', 'auto', {'name': 'orig'}, {'siteSpeedSampleRate': 2} ); // Set the same variables for aggregate data profile ga( 'create', 'UA-19684343-45', 'auto', {'name': 'agg'}, {'siteSpeedSampleRate': 2} ); //GA.js for tracking outbound links function trackOutboundLink(link, category, action, redirect) { try{ ga('orig.send', 'event', category, action); } catch(err) {} try{ ga('agg.send', 'event', category, action); } catch(err) {} //Timer to prevent redirect before processing data - not necessary if opening tab in new window if(redirect){ setTimeout(function(){ document.location.href = link.href; }, 100); } } $(document).ready(function() { $(".outboundlink").click(function() { trackOutboundLink(this, 'outboundlink', this.link, this.target != '_blank'); }); }); ga("orig.set", { "dimension1": "Michael Gibney", "dimension2": "Nov 21, 2024", "dimension3": "Pharma, Research & Development", "dimension4": "Cancer", "dimension5": "20241121", "dimension6": "Article", }); ga("agg.set", { "dimension3": "Michael Gibney", "dimension7": "Nov 21, 2024", "dimension5": "Pharma, Research & Development", "dimension6": "Cancer", "dimension4": "20241121", "dimension8": "Article", "dimension11": "False", }); var diveSendPageviewEvent = true; if (diveSendPageviewEvent === true) { ga('orig.send', 'pageview'); ga('agg.send', 'pageview'); console.log('Queued sending of the pageview event to Google Analytics.'); } else { console.log('Sending the Google Analytics pageview event is disabled for this page.'); } // Actually track outbound links // Not sure if this is being used? var trackOutboundRegisterLink = function (url) { ga('agg.send', 'event', 'event_register', url, 'Registered for event', {'hitCallback': function () { document.location = url; } }); }; // Not sure if this is being used? var trackOutboundWebsiteLink = function (url) { // No need to manually change document.location; website opens in new tab ga('agg.send', 'event', 'event_website', url, 'Visited event site'); }; </script> <script type="module" src="/static/js/dist/googleAnalyticsHelper.bundle.js?520216211124" ></script> <script type="text/javascript"> function read_cookie(cookieName) { var re = new RegExp('[; ]'+cookieName+'=([^\\s;]*)'); var sMatch = (' '+document.cookie).match(re); if (cookieName && sMatch) return unescape(sMatch[1]); return ''; } var script = document.createElement('script'); script.type = 'text/javascript'; script.async = true; script.addEventListener('load', function(e) { // we only pass the template this context variable on newsposts let informaData = false; informaData = {"canonicalUrl": "https://www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/", "pageIsSponsored": false, "pageSponsor": "", "contentAuthor": "Michael Gibney", "contentPubDate": "2024-11-21 07:12:57", "pageID": "newspost 733544", "pageTitle": "Keytruda represents almost half of Merck\u2019s sales, and a new formulation could fend off rivals", "pageType": "article", "primaryTerm": "Pharma, Research & Development", "secondaryTerm": "Cancer"}; if (window.IIRISTracker) { var sailthru_id = read_cookie('sailthru_hid'); if (sailthru_id.length > 56) { sailthru_id = sailthru_id.slice(32,56); } var notProduction = 'False' === 'True'; var domain = 'www.pharmavoice.com'.split('.')[1]; // on non-prod environment, there is specific collector domain to send the data to. var cDomain = notProduction ? 'com-informa-prod1.mini.snplow.net' : 'c.' + domain + '.com' // removed .com previous line var cfg = { config: { td: {}, snowplow: { context: {} } } }; cfg.config.idsource = 'sailthruid'; cfg.config.snowplow.appId = domain; cfg.config.snowplow.cDomain = cDomain; cfg.config.td.lob = 'it'; cfg.config.td.domain = domain; cfg.config.snowplow.contentTagEnabled = !!informaData cfg.config.snowplow.context = informaData window.IIRISTracker.initConfig(cfg); window.IIRISTracker.setTrackingUID(sailthru_id); var irisEvt = new Event('trackerLoaded'); window.dispatchEvent(irisEvt); } else { window.addEventListener('trackerLoaded', function(evt) { if(window.IIRISTracker) { window.IIRISTracker.setTrackingUID(sailthru_id); } }); } }); script.src = 'https://static.iris.informa.com/widgets/v3.0/iris-t.js'; document.getElementsByTagName('head')[0].appendChild(script); </script> <script type="text/javascript"> jQuery.browser = {}; (function () { jQuery.browser.msie = false; jQuery.browser.version = 0; if (navigator.userAgent.match(/MSIE ([0-9]+)\./)) { jQuery.browser.msie = true; jQuery.browser.version = RegExp.$1; } })(); </script>  <script type="text/javascript" src="/static/js/jquery.simplemodal.divefork.min.js?093716120922"></script> <style> /* dynamic style overrides based on DB go here*/ </style> <meta name="sailthru.title" content="Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals" /> <meta name="sailthru.post_type" content="Article" /> <meta name="sailthru.dive_awards" content="False" /> <meta name="sailthru.post_updated" content="False" /> <meta name="lytics:topics" content="Cancer, Pharma, Research & Development" /> <meta name="robots" content="max-image-preview:large"> <meta name="news_keywords" content="Pharma,pharma,Research & Development,research-development"/> <script type="text/javascript"> /** Stolen from http://stackoverflow.com/questions/24816/escaping-html-strings-with-jquery **/ $(document).ready(function () { //"Tweet this" pullquote sections // This is used in the processing of 'tweet this' pull quotes function escapeHtml(string) { var entityMap = { "&": "&", "<": "<", ">": ">", '"': '"', "'": ''', "/": '/' }; return String(string).replace(/[&<>"'\/]/g, function (s) { return entityMap[s]; }); } // Process the twitter pullquote sections: // * create the link // * create the text ('tweet this quote') for the link $(".pquote").each(function (index) { var j_words; if ($(this).data('twitter-text') != 'undefined') { j_words = $(this).children('.tweetwords').first(); } else { j_words = $(this).data('twitter-text'); } var j_replace = $(this).children('.tweetquote').first(); var clean_text = escapeHtml(j_words.text()); var link_attributes = 'href="https://twitter.com/intent/tweet?text=' + clean_text + '%20https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/' + '" class="popup button twitter" data-sharebutton="tweet_quote" data-shareusing="twitter"'; var img = '<img src="/static/img/social_icons/twitter-follow-icon.png?102717100918" alt="Share on Twitter" loading="lazy">'; var link = '<a ' + link_attributes + '>Tweet this quote' + img + '</a>'; j_replace.html(link); }); }); </script> <script data-cfasync="false" type="text/javascript" src="/static/js/prestitial.js?270116210524"></script> <script async src="https://securepubads.g.doubleclick.net/tag/js/gpt.js"></script> <script src="/static/js/dist/signupDataGam.bundle.js?520216211124"></script> <script type="text/javascript" src="/static/js/dist/adTemplates.bundle.js?520216211124"></script> <script> var eventMethod = window.addEventListener ? "addEventListener" : "attachEvent"; var eventer = window[eventMethod]; var messageEvent = eventMethod == "attachEvent" ? "onmessage" : "message"; // Build the site_logos object to be later referenced in house ads const site_logos = {}; site_logos['diveapi'] = { domain: 'diveapi', site_name: "API Site", alt_text: "API Site logo", is_current_site: false, white: { png: "None", svg: "None", }, black: { png: "None", svg: "None", } }; site_logos['agriculturedive'] = { domain: 'agriculturedive', site_name: "Agriculture Dive", alt_text: "Agriculture Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/agriculture_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/agriculture_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/agriculture_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/agriculture_black.svg", } }; site_logos['automotivedive'] = { domain: 'automotivedive', site_name: "Automotive Dive", alt_text: "Automotive Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/automotive_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/automotive_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/automotive_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/automotive_black.svg", } }; site_logos['bankingdive'] = { domain: 'bankingdive', site_name: "Banking Dive", alt_text: "Banking Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/banking_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/banking_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/banking_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/banking_black.svg", } }; site_logos['biopharmadive'] = { domain: 'biopharmadive', site_name: "BioPharma Dive", alt_text: "BioPharma Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/biopharma_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/biopharma_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/biopharma_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/biopharma_black.svg", } }; site_logos['cfo'] = { domain: 'cfo', site_name: "CFO.com", alt_text: "CFO.com logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfodotcom_white.svg", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfodotcom_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfodotcom_black.svg", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfodotcom_black.svg", } }; site_logos['cfodive'] = { domain: 'cfodive', site_name: "CFO Dive", alt_text: "CFO Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfo_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfo_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfo_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cfo_black.svg", } }; site_logos['ciodive'] = { domain: 'ciodive', site_name: "CIO Dive", alt_text: "CIO Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cio_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cio_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cio_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cio_black.svg", } }; site_logos['constructiondive'] = { domain: 'constructiondive', site_name: "Construction Dive", alt_text: "Construction Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/construction_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/construction_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/construction_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/construction_black.svg", } }; site_logos['cstoredive'] = { domain: 'cstoredive', site_name: "C-Store Dive", alt_text: "C-Store Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cstore_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cstore_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cstore_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cstore_black.svg", } }; site_logos['customerexperiencedive'] = { domain: 'customerexperiencedive', site_name: "CX Dive", alt_text: "CX Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cx_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cx_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cx_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cx_black.svg", } }; site_logos['cybersecuritydive'] = { domain: 'cybersecuritydive', site_name: "Cybersecurity Dive", alt_text: "Cybersecurity Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cybersecurity_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cybersecurity_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cybersecurity_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/cybersecurity_black.svg", } }; site_logos['educationdive'] = { domain: 'educationdive', site_name: "Education Dive", alt_text: "Education Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/education_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/education_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/education_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/education_black.svg", } }; site_logos['esgdive'] = { domain: 'esgdive', site_name: "ESG Dive", alt_text: "ESG Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/esg_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/esg_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/esg_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/esg_black.svg", } }; site_logos['facilitiesdive'] = { domain: 'facilitiesdive', site_name: "Facilities Dive", alt_text: "Facilities Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/facilities_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/facilities_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/facilities_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/facilities_black.svg", } }; site_logos['fashiondive'] = { domain: 'fashiondive', site_name: "Fashion Dive", alt_text: "Fashion Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/fashion_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/fashion_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/fashion_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/fashion_black.svg", } }; site_logos['fooddive'] = { domain: 'fooddive', site_name: "Food Dive", alt_text: "Food Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/food_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/food_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/food_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/food_black.svg", } }; site_logos['grocerydive'] = { domain: 'grocerydive', site_name: "Grocery Dive", alt_text: "Grocery Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/grocery_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/grocery_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/grocery_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/grocery_black.svg", } }; site_logos['healthcaredive'] = { domain: 'healthcaredive', site_name: "Healthcare Dive", alt_text: "Healthcare Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/healthcare_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/healthcare_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/healthcare_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/healthcare_black.svg", } }; site_logos['highereddive'] = { domain: 'highereddive', site_name: "Higher Ed Dive", alt_text: "Higher Ed Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/highered_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/highered_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/highered_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/highered_black.svg", } }; site_logos['hoteldive'] = { domain: 'hoteldive', site_name: "Hotel Dive", alt_text: "Hotel Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hotel_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hotel_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hotel_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hotel_black.svg", } }; site_logos['hrdive'] = { domain: 'hrdive', site_name: "HR Dive", alt_text: "HR Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hr_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hr_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hr_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/hr_black.svg", } }; site_logos['k12dive'] = { domain: 'k12dive', site_name: "K-12 Dive", alt_text: "K-12 Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/k12_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/k12_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/k12_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/k12_black.svg", } }; site_logos['legaldive'] = { domain: 'legaldive', site_name: "Legal Dive", alt_text: "Legal Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/legal_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/legal_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/legal_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/legal_black.svg", } }; site_logos['manufacturingdive'] = { domain: 'manufacturingdive', site_name: "Manufacturing Dive", alt_text: "Manufacturing Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/manufacturing_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/manufacturing_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/manufacturing_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/manufacturing_black.svg", } }; site_logos['marketingdive'] = { domain: 'marketingdive', site_name: "Marketing Dive", alt_text: "Marketing Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/marketing_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/marketing_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/marketing_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/marketing_black.svg", } }; site_logos['medtechdive'] = { domain: 'medtechdive', site_name: "MedTech Dive", alt_text: "MedTech Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/medtech_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/medtech_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/medtech_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/medtech_black.svg", } }; site_logos['mobilemarketer'] = { domain: 'mobilemarketer', site_name: "Mobile Marketer", alt_text: "Mobile Marketer logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/mobilemarketer_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/mobilemarketer_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/mobilemarketer_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/mobilemarketer_black.svg", } }; site_logos['multifamilydive'] = { domain: 'multifamilydive', site_name: "Multifamily Dive", alt_text: "Multifamily Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/multifamily_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/multifamily_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/multifamily_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/multifamily_black.svg", } }; site_logos['packagingdive'] = { domain: 'packagingdive', site_name: "Packaging Dive", alt_text: "Packaging Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/packaging_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/packaging_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/packaging_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/packaging_black.svg", } }; site_logos['paymentsdive'] = { domain: 'paymentsdive', site_name: "Payments Dive", alt_text: "Payments Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/payments_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/payments_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/payments_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/payments_black.svg", } }; site_logos['pharmavoice'] = { domain: 'pharmavoice', site_name: "PharmaVoice", alt_text: "PharmaVoice logo", is_current_site: true, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/pharmavoice_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/pharmavoice_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/pharmavoice_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/pharmavoice_black.svg", } }; site_logos['proformative'] = { domain: 'proformative', site_name: "Proformative", alt_text: "Proformative logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/proformative_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/proformative_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/proformative_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/proformative_black.svg", } }; site_logos['restaurantdive'] = { domain: 'restaurantdive', site_name: "Restaurant Dive", alt_text: "Restaurant Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/restaurant_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/restaurant_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/restaurant_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/restaurant_black.svg", } }; site_logos['retaildive'] = { domain: 'retaildive', site_name: "Retail Dive", alt_text: "Retail Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/retail_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/retail_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/retail_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/retail_black.svg", } }; site_logos['smartcitiesdive'] = { domain: 'smartcitiesdive', site_name: "Smart Cities Dive", alt_text: "Smart Cities Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smartcities_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smartcities_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smartcities_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smartcities_black.svg", } }; site_logos['socialmediatoday'] = { domain: 'socialmediatoday', site_name: "Social Media Today", alt_text: "Social Media Today logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smt_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smt_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smt_color.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/smt_color.svg", } }; site_logos['supplychaindive'] = { domain: 'supplychaindive', site_name: "Supply Chain Dive", alt_text: "Supply Chain Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/supplychain_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/supplychain_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/supplychain_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/supplychain_black.svg", } }; site_logos['truckingdive'] = { domain: 'truckingdive', site_name: "Trucking Dive", alt_text: "Trucking Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/trucking_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/trucking_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/trucking_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/trucking_black.svg", } }; site_logos['utilitydive'] = { domain: 'utilitydive', site_name: "Utility Dive", alt_text: "Utility Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/utility_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/utility_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/utility_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/utility_black.svg", } }; site_logos['wastedive'] = { domain: 'wastedive', site_name: "Waste Dive", alt_text: "Waste Dive logo", is_current_site: false, white: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/waste_white.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/waste_white.svg", }, black: { png: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/waste_black.png", svg: "https://d12v9rtnomnebu.cloudfront.net/logo/publications/waste_black.svg", } }; // Get the dive domain and return the dive logo object, or null if it doesn't exist in site_logos function getDivesiteLogoObject(link_url, alt_domain='') { let dive_domain; // Split link URL on 'adurl=' and take what comes after as the ad url const ad_url = decodeURIComponent(link_url.split('adurl=')[1]); // Split on . to get an array of hostname segments const dive_domain_array = new URL(ad_url).hostname.split('.'); // Retrieve the second to last element of the hostname array, which should always be the domain dive_domain = dive_domain_array[dive_domain_array.length - 2] if (alt_domain) { // If alt_domain has been specified, normalize it. i.e. "HR Dive", "http://hrdive.com", etc. => "hrdive" // This will override the link url's domain. dive_domain = alt_domain.replace(/\s+/g, '').replace(/^(https?:\/\/)?(www\.)?|\.com.*|\?.*|#.*/gi, '').toLowerCase(); } // Return the site logos object for this domain if it exists, or null if it does not if (site_logos[dive_domain]) { return site_logos[dive_domain]; } else { // Fallback logo const url_prefix = "https://d12v9rtnomnebu.cloudfront.net/divesite/responsive_ad_assets/small_logos/"; return { domain: 'industrydive', site_name: 'Industry Dive', alt_text: 'Industry Dive logo', white: { svg: url_prefix + 'industrydive-small-white.svg', png: url_prefix + 'industrydive-small-white.png', }, black: { svg: url_prefix + 'industrydive-small-black.svg', png: url_prefix + 'industrydive-small-black.png', } } } } eventer(messageEvent, function (e) { var key = e.message ? "message" : "data"; var data = e[key]; var eventName = data.message || 'ignore'; if (eventName == 'adContentAvailable') { var $ad_element; $ad_element = $('div').filter('[data-container-ad-unit-id="' + data.adUnit + '-' + window.dfp_visibility + '"]'); $ad_element.hide() var nativeAdEditorialSelector = '.sidebar .hybrid-ad-wrapper .native-ad-editorial'; var nativeAdEditorialExists = $(nativeAdEditorialSelector).length > 0; if ( nativeAdEditorialExists ) { $(nativeAdEditorialSelector).closest('.hybrid-ad-wrapper').addClass('native-ad-editorial-sidebar-border'); } // Inline homepage ad $('.feed-item-ad .hybrid-ad-wrapper a').each(function (index, element) { window.updateGamAdUrl(element, 'inline'); }); // Editorial native ad sidebar // NOTE: must go before inline native ad to ensure correct location added $('.sidebar .native-ad.editorial a').each(function (index, element) { window.updateGamAdUrl(element, 'sidebar'); }); // Editorial native ad inline $('.native-ad.editorial a').each(function (index, element) { window.updateGamAdUrl(element, 'inline'); }); // Sidebar ad $('.sidebar .hybrid-ad-wrapper a').each(function (index, element) { window.updateGamAdUrl(element, 'sidebar'); }); } }, false); var googletag = googletag || {}; googletag.cmd = googletag.cmd || []; googletag.cmd.push(function () { var desktopWidth = 1024; if (window.innerWidth >= desktopWidth) { window.dfp_visibility = 'desktop'; } else { window.dfp_visibility = 'mobile'; } var dfpDisplayConfiguration = { "prestitialEnabled": true, "leaderboardEnabled": true, "sidebarAdsEnabled": true, "visibility": window.dfp_visibility }; if (window.dfp_visibility == 'desktop') { if (typeof prestitialAds == 'object' && prestitialAds.pageIsPrestitialEligible()) { googletag.defineSlot('/21662595662/pharmavoice/pharmavoiceprestitial', [[500, 300], [640, 480]], 'paychekgoeshere').addService(googletag.pubads()); } if (dfpDisplayConfiguration.leaderboardEnabled) { googletag.defineSlot('/21662595662/pharmavoice/pharmavoiceleaderboard', [[970, 180], [728, 90], [970, 90]], 'dfp-leaderboard-desktop').addService(googletag.pubads()); googletag.pubads().addEventListener('slotRenderEnded', function (event) { if ((event.slot.getAdUnitPath() === '/21662595662/pharmavoice/pharmavoiceleaderboard' || event.slot.getAdUnitPath() === '/21662595662/pharmavoice/pharmavoiceleaderboard') && !event.isEmpty ) { $(window).blur(function () { if (document.activeElement === $('#dfp-leaderboard-desktop iframe')[0] || document.activeElement === $('#dfp-leaderboard-desktop iframe')[0]) { try { localStorage.setItem('leaderboard_signup_path', document.location.pathname); } catch (e) { // local storage could not be available due to privacy settings or something } } }); } }); } if (dfpDisplayConfiguration.sidebarAdsEnabled) { googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid1', [[300, 250], 'fluid', [160, 600]], 'dfp-hybrid1-desktop').addService(googletag.pubads()); } googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid2', [[300, 250], 'fluid'], 'dfp-hybrid2-desktop').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid3', [[300, 250], 'fluid'], 'dfp-hybrid3-desktop').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid4', [[300, 250], 'fluid'], 'dfp-hybrid4-desktop').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicethankyouhybrid1', ['fluid'], 'dfp-thankyouhybrid1-desktop').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicethankyouhybrid2', ['fluid'], 'dfp-thankyouhybrid2-desktop').addService(googletag.pubads()); } else { googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid1', [[300, 250], 'fluid'], 'dfp-hybrid1-mobile').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid2', [[300, 250], 'fluid'], 'dfp-hybrid2-mobile').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid3', [[300, 250], 'fluid'], 'dfp-hybrid3-mobile').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicehybrid4', [[300, 250], 'fluid'], 'dfp-hybrid4-mobile').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicethankyouhybrid1', ['fluid'], 'dfp-thankyouhybrid1-mobile').addService(googletag.pubads()); googletag.defineSlot('/21662595662/pharmavoice/pharmavoicethankyouhybrid2', ['fluid'], 'dfp-thankyouhybrid2-mobile').addService(googletag.pubads()); } googletag.pubads().setTargeting("topics", ["Pharma","pharma","Research & Development","research-development"]); googletag.pubads().setTargeting("tags", ["pharmavoice-tag-cancer"]); if ((typeof divecounter !== "undefined") && (divecounter.getData().is_subscriber)) { googletag.pubads().setTargeting("is_subscriber", "yes"); } var site = window.location.host; googletag.pubads().setTargeting("site", site); var first_path = window.location.pathname.split( '/' )[1]; googletag.pubads().setTargeting("first_path", first_path); googletag.pubads().setTargeting("newspost_type", "Article"); googletag.pubads().setTargeting("articleID", "733544"); googletag.pubads().setTargeting("slug", "merck keytruda cancer oncology subcutaneous roche bristol myers"); googletag.pubads().setTargeting("is_sponsored", "false" ); // Don't show skyscraper ads on full-width articles googletag.pubads().setTargeting("show_skyscraper", "true"); // Set ad targeting on the trendline to show the ads designated for it var isTopicPage = window.location.pathname.indexOf('/topic/') !== -1; if(isTopicPage) { googletag.pubads().setTargeting('is_topics_page', 'true'); } googletag.pubads().setCentering(true); googletag.pubads().collapseEmptyDivs(false); // Whether to collapse the slots even before the ads are fetched. googletag.pubads().enableSingleRequest(); googletag.enableServices(); }); </script> <script>window.fallbackAds = '[{\u0022adType\u0022: \u0022editorial_native_ad\u0022, \u0022link\u0022: \u0022/trendline/clinical\u002Dtrial\u002Ddiversity/341/?utm_source\u003DPV\u0026utm_medium\u003DNativeFB\u0026utm_campaign\u003DTrendlineFB\u0022, \u0022label\u0022: \u0022Trendline\u0022, \u0022image\u0022: \u0022https://imgproxy.divecdn.com/T52rDmmleIjhBOQnv3BbjO5MEVj\u002D_ZDOpk_KtIa7Cz0/g:ce/rs:fit:212:100/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xMzY0OTgwMjkwLmpwZw\u003D\u003D.webp\u0022, \u0022attribution\u0022: \u0022\u0022, \u0022headline\u0022: \u0022Increasing diversity in clinical trials\u0022, \u0022ctaText\u0022: \u0022Access now\u0022, \u0022description\u0022: \u0022As pharma wises up to the fact that the current playbook for improving clinical trial diversity has yet to make a meaningful impact, the quest is on to refine that approach.\u0022}, {\u0022adType\u0022: \u0022editorial_native_ad\u0022, \u0022link\u0022: \u0022/trendline/oncology\u002Dcancer\u002Dcare/356/?utm_source\u003DPV\u0026utm_medium\u003DNativeFB\u0026utm_campaign\u003DTrendlineFB\u0022, \u0022label\u0022: \u0022Trendline\u0022, \u0022image\u0022: \u0022https://imgproxy.divecdn.com/\u002DIGqm4N8ki4Li7ddTtOWtZ8aU0Ll9SESXTF_CFyVhiw/g:ce/rs:fit:212:100/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDc3NDgyMTYzLmpwZw\u003D\u003D.webp\u0022, \u0022attribution\u0022: \u0022\u0022, \u0022headline\u0022: \u0022The latest advances in cancer research\u0022, \u0022ctaText\u0022: \u0022Access now\u0022, \u0022description\u0022: \u0022As investments in cancer R\u0026D stay high, waves of innovative new treatments are on the horizon.\u0022}, {\u0022adType\u0022: \u0022editorial_native_ad\u0022, \u0022link\u0022: \u0022/trendline/commercialization\u002Dmarketing\u002Dsocial\u002Dmedia/480/?utm_source\u003DPV\u0026utm_medium\u003DNativeFB\u0026utm_campaign\u003DTrendlineFB\u0022, \u0022label\u0022: \u0022Trendline\u0022, \u0022image\u0022: \u0022https://imgproxy.divecdn.com/zkvKuMJ3B\u002DslbC3F\u002DkgVzoOg7C5CS6ZERKSS\u002Dq3NveU/g:ce/rs:fit:212:100/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy04NDcyNDgzOTguanBn.webp\u0022, \u0022attribution\u0022: \u0022\u0022, \u0022headline\u0022: \u0022Top market strategies for today\u005Cu2019s pharma landscape\u0022, \u0022ctaText\u0022: \u0022Access now\u0022, \u0022description\u0022: \u0022As the pharma industry stares down a historic patent cliff, macroeconomic headwinds and challenging R\u0026D costs for increasingly complex medicines, nailing the launch of new medicines has become increasingly critical.\u005Cu00a0\u0022}]'</script> <script type="module" src="/static/js/dist/onBoardDiagnostics.bundle.js?520216211124" ></script>  </head> <body class=" flush-top article-page news topic- pharma topic- research-development ">  <a href="#skip-link-target" class="button button--loud skip-nav-link" tabindex="1">Skip to main content</a>  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-55G8WRR" height="0" width="0" style="display:none;visibility:hidden"> </iframe></noscript>  <div id="prestitial-init" style="display: none;" class="prestitial-init"></div> <div id="prestitial-outer" class="prestitial content-overlay" style="display:none;"> <section class="site-menu" aria-label="Site menu"> <div class="site-menu-inner"> <img src="https://d12v9rtnomnebu.cloudfront.net/logo/publications/pharmavoice_black.svg" alt="PharmaVoice" class="pub-logo"> </div> </section> <section class="paychek-page-wrapper row"> <div class="paychek-button large-4 large-push-8 columns"> <div> CONTINUE TO SITE ➞ </div> </div> <div class="paychek large-8 large-pull-4 columns"> <div id="paychekgoeshere"></div> <script data-cfasync="false" type="text/javascript"> if (typeof prestitialAds !== 'undefined' && prestitialAds.pageIsPrestitialEligible()) { prestitialAds.showOverlay(); } </script> <script type="text/javascript"> if (typeof prestitialAds !== 'undefined' && prestitialAds.pageIsPrestitialEligible()) { prestitialAds.initialize(7); prestitialAds.setPrestitialPossibleCookie(); var prestitial_ad_is_loaded = false; var prestitial_ad_is_empty = false; googletag.cmd.push(function () { googletag.pubads().addEventListener('slotRenderEnded', function (event) { if (event.slot.getAdUnitPath() == '/21662595662/pharmavoice/pharmavoiceprestitial') { if (event.isEmpty || prestitialAds.testingNoAd()) { prestitial_ad_is_empty = true; prestitialAds.closePrestitial(); } else { prestitial_ad_is_loaded = true; $.modal.close(); $('div#prestitial-init').hide(); // hide the all white overlay prestitialAds.setCookie( "_prestitialViewed", (new Date()).getTime(), prestitialAds.daysBetweenPrestitial ); } } }); }); if (prestitialAds.testingNoAd()) { } else { waitToLoadAds.push(function() { googletag.cmd.push(function () { googletag.display('paychekgoeshere'); }); }); } setTimeout( function () { if (!prestitial_ad_is_loaded && !prestitialAds.overrideTimeout()) { if (!prestitial_ad_is_empty) { // if the prestitial is already hidden, then don't hide it again. if (!prestitialAds.prestitialAdIsClosed()) { prestitialAds.closePrestitial(); prestitialAds.logClosePrestitialAdBy('failed'); } } } else if (!prestitialAds.overrideTimeout()) { setTimeout( function () { // if the prestitial is already hidden, then don't hide it again. if (!prestitialAds.prestitialAdIsClosed()) { prestitialAds.closePrestitial(); prestitialAds.logClosePrestitialAdBy('timeout'); } }, prestitialAds.timeoutSeconds() ); } else { } }, 2900 ); prestitialAds.sentPrestitialEligibleEvent(); } else if (typeof prestitialAds !== 'undefined' && !prestitialAds.pageIsPrestitialEligible()){ prestitialAds.closePrestitial(); } </script> </div> </section> </div> <div id="signup-inter" class="modal_dialog" style="display:none;"> <form id="signup-inter-form" class="form-basic" name="signup-inter-form" action="/signup/" method="POST"> <input type="hidden" name="signup_box_location" value="interstitial"> <input type="hidden" name="signup_initial_url_path" value="/"> <h1> Don't miss the most important voices in pharma </h1> <p class="interstitial-text"> Let PharmaVoice's free newsletter keep you informed on what industry leaders are saying, straight from your inbox. </p> <p class="form-error__message" id="interstitial-error"></p> <div id="form-interstitial"> <input type="email" name="email" placeholder="Work email address" class="email" required id="id_22ae24_email"> <div id="newsletter-list-section"> </div> <div id="interstitial-consent-container"> <input name="user_consent" value="1" id="id_user_consent" type="checkbox"> <span> By signing up to receive our newsletter, you agree to our <a href="https://www.industrydive.com/terms-of-use/" target="_blank">Terms of Use</a> and <a href="https://www.industrydive.com/privacy-policy/" target="_blank">Privacy Policy</a>. You can unsubscribe at anytime. </span> </div> </div> <input id="signup-inter-submit" class="email_submit submit button" type="submit" data-role="none" value="Subscribe today"> </form> </div>  <div class="leaderboard-wrap"> <div class="hide-small show-large"> <div data-container-ad-unit-id="/21662595662/pharmavoice/pharmavoiceleaderboard-desktop"></div> <div id='dfp-leaderboard-desktop' style="min-height: 90px"> <script> waitToLoadAds.push(function() { googletag.cmd.push(function() { if (window.dfp_visibility == 'desktop') { googletag.display('dfp-leaderboard-desktop'); } }) }); </script> </div> </div> </div> <div class="page-container"> <header role="banner"> <nav id="top" class="site-menu" aria-label="Site menu"> <div class="site-menu-inner">  <div class="pub-logo-wrapper"> <a href="/" class="analytics t-dash-navigation-top"> <img class="pub-logo" src="https://d12v9rtnomnebu.cloudfront.net/logo/publications/pharmavoice_black.svg" alt="PharmaVoice" height="28"> </a> </div>  <div class="menu-content-wrapper"> <ul class="desktop-menu-main"> <li class="pv-top-nav-dropdown-item js-top-nav-item-visible js-top-nav-item-active"> <button class="nav-menu-item topics-dropdown-item analytics t-voices-navigation-top"> Voices <span class="dropdown-toggle-arrow pharmavoice"></span> </button> <ul class="top-nav-dropdown-menu"> <li class="top-nav-dropdown-menu-item"> <a href="/q-and-a" class="nav-menu-item analytics t-voices-navigation-qanda"> Q&A </a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/profiles" class="nav-menu-item analytics t-voices-navigation-profiles"> Profiles </a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/biotech-spotlight/" class="nav-menu-item analytics t-voices-navigation-biotechspotlight"> Biotech Spotlight </a> </li> <li class="/top-nav-dropdown-menu-item"> <a href="/topic/first-90-days/" class="nav-menu-item analytics t-voices-navigation-first90days"> First 90 Days </a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/opinion" class="nav-menu-item analytics t-voices-navigation-opinions"> Opinions </a> </li> </ul> </li> <li class="pv-top-nav-dropdown-item pv-top-nav-dropdown-item-topics"> <button class="nav-menu-item topics-dropdown-item analytics t-topic-navigation-top"> Topics <span class="dropdown-toggle-arrow pharmavoice"></span> </button> <ul class="top-nav-dropdown-menu"> <li class="top-nav-dropdown-menu-item"> <a href="/topic/biotech/" class="nav-menu-item analytics t-topic-navigation-biotech">Biotech</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/commercialization/" class="nav-menu-item analytics t-topic-navigation-commercialization">Commercialization</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/leadership/" class="nav-menu-item analytics t-topic-navigation-leadership">Leadership</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/manufacturing/" class="nav-menu-item analytics t-topic-navigation-manufacturing">Manufacturing</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/patient/" class="nav-menu-item analytics t-topic-navigation-patient">Patient</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/pharma/" class="nav-menu-item analytics t-topic-navigation-pharma">Pharma</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/policy-regulation/" class="nav-menu-item analytics t-topic-navigation-policy-regulation">Policy & Regulation</a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/topic/research-development/" class="nav-menu-item analytics t-topic-navigation-research-development">Research & Development</a> </li> </ul> </li> <li> <a href="/library/" class="nav-menu-item analytics t-library-navigation">Library</a> </li> <li> <a href="/events/" class="nav-menu-item analytics t-events-navigation">Events</a> </li> <li> <a href="/press-release/" class="nav-menu-item analytics t-press-releases-navigation">Press Releases</a> </li> <li class="pv-top-nav-dropdown-item"> <button class="nav-menu-item topics-dropdown-item analytics t-pv100-navigation-top"> PharmaVoice 100 <span class="dropdown-toggle-arrow pharmavoice"></span> </button> <ul class="top-nav-dropdown-menu"> <li class="top-nav-dropdown-menu-item"> <a href="https://www.pharmavoice.com/news/pharmavoice-100-nomination-form/611747/" class="nav-menu-item analytics t-pv100-navigation-nominate"> Nominate </a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/news/pv100-pharma-leaders-executives/726233/" class="nav-menu-item analytics t-pv100-navigation-current100"> 2024 PV100 </a> </li> <li class="top-nav-dropdown-menu-item"> <a href="/news/pharmavoice100-pv100-pharma-leaders/690951/" class="nav-menu-item analytics t-pv100-navigation-past"> 2023 PV100 </a> </li> </ul> </li> </ul>  <a href="/signup/?signup_location=header" class="nav-menu-item nav-signup-button mobile-nav-signup-button analytics t-signup-navigation button"> Sign up </a> <button class="mobile-menu-toggle"> <img src="/static/img/menu_icons/menu.svg?273117231121" alt="menu" loading="lazy"> </button>  <ul class="desktop-menu-sub list-no-bullets"> <li> <button class="nav-menu-item search-button-front search-toggle analytics t-search-navigation-top"> <img src="/static/img/menu_icons/search.svg?320116291121" alt="search" width="16" height="16" loading="lazy"> <span class="sub-link">Search</span> </button> </li> <li> <a href="/signup/?signup_location=header" class="nav-menu-item nav-signup-button desktop-nav-signup-button analytics t-signup-navigation button"> <img src="/static/img/email_icons/mail.svg?273117231121" width="16" height="11" loading="lazy" alt=""> Sign up </a> </li> </ul> </div> </div> </nav> </header> <div class="menu-search js-search-hide"> <div class="menu-search-inner-wrapper row"> <form action="/search/" method="GET"> <label for="search-desktop"> <span class="screen-reader-text search">Search</span> </label> <input id="search-desktop" type="Search" name="q" placeholder="search"> <button type="submit" value="" class="search-button-front analytics t-search-navigation-drawer"> <img src="/static/images/proformative_search_glass_black.svg?231516061021" width="18" height="18" alt="search" loading="lazy"> </button> <img class="close" src="/static/img/menu_icons/close.svg?273117231121" width="16" height="16" loading="lazy" alt="close search"> </form> </div> </div> <script type="module" src="/static/js/dist/pharmavoiceNav.bundle.js?520216211124" ></script> <script type="module" src="/static/js/dist/navSignupHelper.bundle.js?520216211124" ></script> <div class="search-overlay"></div> <div class="page-wrapper"> <div class="page-inner-wrapper" id="skip-link-target"> <div class="row"> <div class="medium-10 medium-centered large-12"> <section id="main-content" class="main-content large-8 columns"> <link rel="preload" as="image" href="https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" imagesrcset="https://imgproxy.divecdn.com/JDjj7rQqn1a6Qk5bII560rvwHblQhnGLcn22n8Zt6Zo/g:ce/rs:fill:400:225:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 400w, https://imgproxy.divecdn.com/vf2KlWp3TGzz3eU95ruJ7QLnFbDKkYfMWKrE0gBPQkc/g:ce/rs:fill:800:450:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 800w, https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 1200w, https://imgproxy.divecdn.com/X8ByT_A14mSpsscZihaGg1BqTUd8WYwW58WYPIDRRSk/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 1600w" imagesizes="(min-width: 64em) 60vw, 100vw" alt=""> <article class=""> <div class="first-page-pdf">  <div class="printed-branding"> <span class="promoted-branded-copy">An article from</span> <img src="https://d12v9rtnomnebu.cloudfront.net/logo/printer_friendly/pharmavoice.jpg" alt="site logo"> </div> <div class="article-title-wrapper"> <div class="post-label-wrapper"> </div> <h1 class="display-heading-04"> Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals </h1> <p>A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market.</p> </div> <div class="byline"> <div class="article-byline"> <div class="date date-bottom-border"> <span class="published-info"> Published Nov. 21, 2024 </span> </div> <div class="byline-row "> <div class="author "> <div class="author-row author-row-flex"> <a href="/editors/mgibney/"> <img class="author-img-round analytics t-article-byline-author" src="https://d1b6lhn2ymmy1x.cloudfront.net/journalist-headshots/gibney-michael-circle-150x150.png" alt="Michael Gibney's headshot"> </a> <div class="author-name author-name-with-headshot"> <a rel="author" href="/editors/mgibney/" class="analytics t-article-byline-author">Michael Gibney</a> <span class="author-title">Senior Editor & Writer</span> </div> </div> </div> <div class="social-share"> <ul class="social-icon-list"> <li> <a href="http://www.linkedin.com/shareArticle?mini=true&url=https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/&title=Keytruda%20represents%20almost%20half%20of%20Merck%E2%80%99s%20sales%2C%20and%20a%20new%20formulation%20could%20fend%20off%20rivals" aria-label="Share article to Linkedin" class="social-icon analytics t-article-byline-social-linkedin"> <img src="/static/img/social_icons/article_page/linkedin.svg?092716141024" alt="Post to LinkedIn"> <span class="social-icon__text">post</span> </a> </li> <li> <a href="https://www.facebook.com/sharer/sharer.php?u=https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" aria-label="Share article to Facebook" class="social-icon analytics t-article-byline-social-facebook"> <img src="/static/img/social_icons/article_page/facebook.svg?440116200824" alt="Share on Facebook"> <span class="social-icon__text">share</span> </a> </li> <li> <a href="https://twitter.com/intent/tweet?text=Keytruda%20represents%20almost%20half%20of%20Merck%E2%80%99s%20sales%2C%20and%20a%20new%20formulation%20could%20fend%20off%20rivals%20https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/%20via%20@PharmaVoice" aria-label="Share article to X/Twitter" class="social-icon analytics t-article-byline-social-twitter"> <img src="/static/img/social_icons/article_page/x.svg?092716141024" alt="Post on X"> <span class="social-icon__text">post</span> </a> </li> <li> <a href="javascript:window.print()" aria-label="Print article" class="social-icon js-social-icon-print"> <img src="/static/img/social_icons/article_page/print.svg?440116200824" alt="Print this page"> <span class="social-icon__text">print</span> </a> </li> <li> <a href="/cdn-cgi/l/email-protection#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" aria-label="Share article with email" class="social-icon analytics t-article-byline-social-email"> <img src="/static/img/social_icons/article_page/email.svg?092716141024" alt="Email this page"> <span class="social-icon__text">email</span> </a> </li> <li> <a href="/selfservice/article-licensing/submit/?newspostUrl=https://www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" aria-label="License article" class="social-icon js-social-icon-license analytics t-article-byline-social-licensing"> <img src="/static/img/social_icons/article_page/cart.svg?092716141024" alt="License this article"> <span class="social-icon__text">license</span> </a> </li> </ul> </div> </div> </div> </div> <figure class="inside_story"> <div class="figure_content article-hero-img"> <img class="" src="https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" width="1200" height="675" srcset="https://imgproxy.divecdn.com/JDjj7rQqn1a6Qk5bII560rvwHblQhnGLcn22n8Zt6Zo/g:ce/rs:fill:400:225:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 400w, https://imgproxy.divecdn.com/vf2KlWp3TGzz3eU95ruJ7QLnFbDKkYfMWKrE0gBPQkc/g:ce/rs:fill:800:450:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 800w, https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 1200w, https://imgproxy.divecdn.com/X8ByT_A14mSpsscZihaGg1BqTUd8WYwW58WYPIDRRSk/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 1600w" sizes="(min-width: 64em) 60vw, 100vw" alt="Keytruda, Merck" > </div> <figcaption class="inside_story_caption"> <span class="source_text"> Permission granted by Merck & Co. </span> </figcaption> </figure> </div> <div class="row"> <div class="article-large-12 columns article-wrapper"> <div class="print-wrapper"> <div class=" large medium article-body"> <div class="text-to-speech"> <button class="text-to-speech__button button"> <img class="text-to-speech__button__icon" src="/static/images/audio_icon.svg?482016190122" alt=""/> Listen to the article <span class="text-to-speech__button__audio-length">4 min</span> </button> <div class="text-to-speech__controls"> <audio controls class="js-text-to-speech" preload="none"> <source src="http://res.cloudinary.com/dmgi9movl/video/upload/q_1/v1732136004/news/text_to_speech/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers_c15zmz.wav" type="audio/mp3"> </audio> <div class="text-to-speech__controls__text"> This audio is auto-generated. Please let us know if you have <a href="/contact/">feedback</a>. </div> </div> </div> <p>As patent protection for the cancer juggernaut Keytruda approaches a critical juncture, Merck & Co. won’t give up market share without a fight. The company <a href="https://www.merck.com/news/merck-announces-phase-3-trial-of-subcutaneous-pembrolizumab-with-berahyaluronidase-alfa-met-primary-endpoints/">revealed this week</a> that a subcutaneous version of the drug — along with chemotherapy — was as effective in a late-stage trial as the original recipe, which is infused intravenously.</p> <p>The results were meaningful to Merck as it seeks to remain a leader in the next generation of cancer care and fend off potential rivals shouldering into the territory.</p> <div class="hybrid-ad-wrapper show-small hide-large"> <div class="hybrid-ad-inner-wrapper"> <div class="show-small hide-large"> <div data-container-ad-unit-id="/21662595662/pharmavoice/pharmavoicehybrid1-mobile"></div> <div id="dfp-hybrid1-mobile"> <script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script> waitToLoadAds.push(function() { googletag.cmd.push(function() { if (window.dfp_visibility == 'mobile' ) { googletag.display('dfp-hybrid1-mobile'); googletag.pubads().addEventListener('slotRenderEnded', function (event) { var adUnitPath = '/21662595662/pharmavoice/pharmavoicehybrid1'; var onProformative = false; if (onProformative && event.slot.getAdUnitPath() === adUnitPath && !event.isEmpty ) { var adUnitPathWithVisibility = adUnitPath + '-mobile'; var selector = '.pf-comments__ad-wrapper [data-container-ad-unit-id="' + adUnitPathWithVisibility + '"]'; if (!$(selector).closest('.pf-comments__ad-wrapper').hasClass('borders')) { $(selector).closest('.pf-comments__ad-wrapper').addClass('borders') } } }); } }); }); </script> </div> </div> </div> </div> <div class="hybrid-ad-wrapper hide-small show-large"> <div class="hybrid-ad-inner-wrapper"> <div class="hide-small show-large"> <div data-container-ad-unit-id="/21662595662/pharmavoice/pharmavoicehybrid2-desktop"></div> <div id="dfp-hybrid2-desktop"> <script> waitToLoadAds.push(function() { googletag.cmd.push(function() { if (window.dfp_visibility == 'desktop' ) { googletag.display('dfp-hybrid2-desktop'); googletag.pubads().addEventListener('slotRenderEnded', function (event) { var adUnitPath = '/21662595662/pharmavoice/pharmavoicehybrid2'; var onProformative = false; if (onProformative && event.slot.getAdUnitPath() === adUnitPath && !event.isEmpty ) { var adUnitPathWithVisibility = adUnitPath + '-desktop'; var selector = '.pf-comments__ad-wrapper [data-container-ad-unit-id="' + adUnitPathWithVisibility + '"]'; if (!$(selector).closest('.pf-comments__ad-wrapper').hasClass('borders')) { $(selector).closest('.pf-comments__ad-wrapper').addClass('borders') } } }); } }); }); </script> </div> </div> </div> </div> <p>Keytruda has been a gamechanger in oncology with 41 indications and $25 billion in sales last year, eclipsing AbbVie’s Humira as the bestselling drug in any therapeutic area. The trouble for Merck, however, is that the massive success has become a load-bearing pillar for the company, representing <a href="https://www.merck.com/news/merck-announces-fourth-quarter-and-full-year-2023-financial-results/">more than 41% of all sales</a> in 2023, a percentage that has grown year over year. In 2022, Keytruda’s sales were only 35% of the company’s as a whole.</p> <p>Even as Merck bolsters its pipeline to make up for lost sales when direct competition enters the market in 2028, the company’s fate is firmly tied to Keytruda for the time being.</p> <h3 class="standard-heading">Competition heats up</h3> <p>Merck isn’t the only subcutaneous checkpoint inhibitor — Roche’s Genentech scored the <a href="https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-atezolizumab-and-hyaluronidase-tqjs-subcutaneous-injection">first U.S. approval</a> for an under-the-skin anti-PDL1 treatment with Tecentriq Hybreza in September. A modified version of Genentech’s bestselling drug Tecentriq, the new product leverages delivery technology from partner Halozyme to cut the injection time down to about seven minutes as opposed to the original intravenous infusion, which can take up to an hour.</p> <p>Comparatively, Keytruda’s subcutaneous version took only two to three minutes to inject, Merck senior vice president and head of oncology global clinical development Dr. Marjorie Green said in a release. Merck’s delivery technology for subcutaneous injection comes from South Korean partner Alteogen.</p> <p>The market for Tecentriq prior to the approval has been only a fraction of Keytruda’s. Roche pulled in $4.2 billion in <a href="https://assets.roche.com/f/176343/x/3b1fb647e2/fb23e.pdf">2023 sales</a> of the drug, giving Merck a much broader base to work with when its own subcutaneous version enters the arena.</p> <div class="hybrid-ad-wrapper show-small hide-large"> <div class="hybrid-ad-inner-wrapper"> <div class="show-small hide-large"> <div data-container-ad-unit-id="/21662595662/pharmavoice/pharmavoicehybrid2-mobile"></div> <div id="dfp-hybrid2-mobile"> <script> waitToLoadAds.push(function() { googletag.cmd.push(function() { if (window.dfp_visibility == 'mobile' ) { googletag.display('dfp-hybrid2-mobile'); googletag.pubads().addEventListener('slotRenderEnded', function (event) { var adUnitPath = '/21662595662/pharmavoice/pharmavoicehybrid2'; var onProformative = false; if (onProformative && event.slot.getAdUnitPath() === adUnitPath && !event.isEmpty ) { var adUnitPathWithVisibility = adUnitPath + '-mobile'; var selector = '.pf-comments__ad-wrapper [data-container-ad-unit-id="' + adUnitPathWithVisibility + '"]'; if (!$(selector).closest('.pf-comments__ad-wrapper').hasClass('borders')) { $(selector).closest('.pf-comments__ad-wrapper').addClass('borders') } } }); } }); }); </script> </div> </div> </div> </div> <div class="hide-small show-large" id="desktop-inline-signup"></div> <p>Tecentriq Hybreza likely won’t be the only other competition in the mix. Bristol Myers Squibb, a longtime rival of Merck’s in the checkpoint inhibitor space, is expected to <a href="https://news.bms.com/news/details/2024/Bristol-Myers-Squibb-Announces-Updated-Action-Date-by-the-U.S.-Food-and-Drug-Administration-for-Subcutaneous-Nivolumab-nivolumab-and-hyaluronidase/default.aspx">hear</a> from the FDA by the end of December about its application for a subcutaneous version of anti-PD1 Opdivo.</p> <p>Sales for the original version of Opdivo, while still far short of Keytruda’s, were over <a href="https://news.bms.com/news/details/2024/Bristol-Myers-Squibb-Reports-Fourth-Quarter-and-Full-Year-Financial-Results-for-2023/default.aspx">$9 billion last year</a> — more than double that of Tecentriq — adding a higher-profile contender to Merck’s subcutaneous peers.</p> <p>Merck’s shares rose <a href="https://www.reuters.com/business/healthcare-pharmaceuticals/merck-says-keytruda-injection-par-with-approved-iv-version-trial-2024-11-19/">almost 2%</a> this week following news of the subcutaneous data. </p> <h3 class="standard-heading">A leading history</h3> <p>Ten years after Keytruda’s original approval, the drug is still growing its market substantially. In a third-quarter earnings call last month, CFO Caroline Litchfield pointed out that sales grew 21% to $7.4 billion, driven by its wide range of indications, including for patients with non-small cell lung cancer.</p> <p>And Merck has been exploring the drug’s potential in earlier lines of cancer treatment, gaining FDA approval for nine indications in earlier-stage settings, according to president of Merck Research Laboratories Dr. Dean Li during the call.</p> <p>Keytruda is also a <a href="https://www.pharmavoice.com/news/keytruda-merck-cancer-lung-long-term-results/633087/">popular choice</a> for companies looking to combine their drugs with a leading checkpoint inhibitor in clinical studies. Merck’s vice president of oncology research Dr. Gregory Lubiniecki told PharmaVoice in 2022 that Keytruda remains a strong choice as a control arm for other cancer trials because “it is such an important part of standard-of-care for many tumors.”</p> </div> <div class="reading-list recommended-reading"> <h3 class="sidebar-box__header reading-list__header">Recommended Reading</h3> <ul class="list-no-bullets"> <li class="reading-list__item"> <a href="https://www.pharmavoice.com/news/keytruda-merck-cancer-lung-long-term-results/633087/" target="_blank" class="reading-list__link analytics t-article-end-recommended"> Keytruda is the gift that keeps on giving for Merck, and here’s what’s next for the cancer juggernaut </a> <span class="label label--soft"> <img src="/static/img/offsite_black.png?102717100918" class="off-site-link" alt="offsite link" width="12" height="12" /> <span>Michael Gibney</span> </span> </li> <li class="reading-list__item"> <a href="https://www.pharmavoice.com/news/big-pharma-oncology-johnson-johnson-merck-abbvie-eisai/698543/" target="_blank" class="reading-list__link analytics t-article-end-recommended"> How Big Pharma keeps the oncology engines hot with a host of strategies </a> <span class="label label--soft"> <img src="/static/img/offsite_black.png?102717100918" class="off-site-link" alt="offsite link" width="12" height="12" /> <span>Michael Gibney</span> </span> </li> </ul> </div> <div class="post-article-wrapper"> <div class="share-buttons"> <ul class="social-button-list"> <li> <a href="http://www.linkedin.com/shareArticle?mini=true&url=https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/&title=Keytruda%20represents%20almost%20half%20of%20Merck%E2%80%99s%20sales%2C%20and%20a%20new%20formulation%20could%20fend%20off%20rivals" class="social-button analytics t-article-end-social-linkedin" title="Post"> <img src="/static/img/social_icons/article_page/linkedin.svg?092716141024" alt="Post to LinkedIn"> </a> </li> <li> <a href="https://www.facebook.com/sharer/sharer.php?u=https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" class="social-button analytics t-article-end-social-facebook" title="Share"> <img src="/static/img/social_icons/article_page/facebook.svg?440116200824" alt="Share on Facebook"> </a> </li> <li> <a href="https://twitter.com/intent/tweet?text=Keytruda%20represents%20almost%20half%20of%20Merck%E2%80%99s%20sales%2C%20and%20a%20new%20formulation%20could%20fend%20off%20rivals%20https%3A//www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/%20via%20@PharmaVoice" class="social-button analytics t-article-end-social-twitter" title="Post"> <img src="/static/img/social_icons/article_page/x.svg?092716141024" alt="Post to X"> </a> </li> <li> <a href="javascript:window.print()" class="social-button js-social-button-print" title="Print"> <img src="/static/img/social_icons/article_page/print.svg?440116200824" alt="Print this page"> </a> </li> <li> <a href="/cdn-cgi/l/email-protection#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" class="social-button analytics t-article-end-social-email" title="Email"> <img src="/static/img/social_icons/article_page/email.svg?092716141024" alt="Email this page"> </a> </li> <li class="article-licensing-item"> <a href="/selfservice/article-licensing/submit/?newspostUrl=https://www.pharmavoice.com/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" class="article-licensing-button js-social-button-license analytics t-article-end-social-licensing" title="License"> <img src="/static/img/social_icons/article_page/cart.svg?092716141024" alt="License this article"> <span class="social-button__text">purchase licensing rights</span> </a> </li> </ul> </div> <div class="post-article-topics"> <div> <span>Filed Under:</span> <span><a class="topic analytics t-article-end-topic" href="/topic/pharma/">Pharma, </a></span> <span><a class="topic analytics t-article-end-topic" href="/topic/research-development/">Research & Development</a></span> </div> </div> </div> </div> </div> </div> </article> <section class="signup call-out elevated-footer standard-newspost-mobile show-small show-medium hide-large"> <div class="row"> <div class="large-11 medium-11 medium-centered columns footer-signup" style="display: flex"> <div class="footer-signup__content"> <h3>PharmaVoice stories and insights delivered to your inbox</h3> <p class="subhead">Get the free daily newsletter read by industry leaders</p> <form class="form js-form-email-validate" name="signup" action="/signup/" method="POST"> <label for="id_f2ccec_email" class="email-input js-email-input"> <span class="screen-reader-text">Email:</span> <input type="email" name="email" placeholder="Work email address" class="email" required id="id_f2ccec_email"> </label> <input type="hidden" name="signup_box_location" value="elevated_footer"> <input type="hidden" name="signup_initial_url_path" value="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <input type="hidden" name="js_enabled" value="0" id="id_f2ccec_js_enabled"> <ul class="signup-list list-no-bullets"> <li> <label><span class="screen-reader-text">Select user consent:</span></label> <input type="checkbox" name="user_consent" id="id_user_consent-elevated_footer" value="1" class="checkbox"/> <label for="id_user_consent-elevated_footer"> <span class="signup-user-consent_box"> <span> By signing up to receive our newsletter, you agree to our <a href="https://www.industrydive.com/terms-of-use/" target="_blank">Terms of Use</a> and <a href="https://www.industrydive.com/privacy-policy/" target="_blank">Privacy Policy</a>. You can unsubscribe at anytime. </span> </span> </label> </li> </ul> <button class="button button--medium signup-button" type="submit" value="Sign up">Sign up</button> <script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="module" src="/static/js/dist/sendEmailToLytics.bundle.js?520216211124" ></script> <label class="error email_error" style="display:none;">A valid email address is required.</label> <label class="error newsletter-error" style="display:none;">Please select at least one newsletter.</label> </form> </div> <div class="footer-signup__image"> <img class="desktop-image" src="/static/img/pharmavoice/signup-article.png?080016020822" width="275" height="275" loading="lazy" alt="PharmaVoice newsletter example"> </div> </div> </div> </section> <div class="sidebar-box hide-large editors-pick-footer-mobile"> <h3 class="sidebar-box__header"> Editors' pick </h3> <ul class="feed"> <li class="row feed__item"> <div class="medium-5 columns"> <figure class="feed__image-container"> <a class="feed__image analytics t-edfooter-edpicks-1" href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <img class="" src="https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" width="1200" height="675" srcset="https://imgproxy.divecdn.com/oxID8_bFYzrMfwQpy92VUm-83IfASezf74akk90ck_Q/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 300w, https://imgproxy.divecdn.com/BX2oEajr6CixdvcJc8r_UPcRDAUh7M5Fcs0NsF7X138/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 600w, https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 1200w" sizes="(min-width: 40em ) 25vw, 100vw" alt="Keytruda, Merck" loading="lazy" > </a> <figcaption> <img class="feed__attribution-icon" src="/static/images/info-icon.png?234917240220" width="16" height="16" alt="Image attribution tooltip" tabindex="0"> <div class="feed__attribution">Permission granted by Merck & Co.</div> <img class="feed__attribution-icon" src="/static/images/info-icon.png?234917240220" width="16" height="16" alt="Image attribution tooltip" tabindex="-1"> </figcaption> </figure> </div> <div class="medium-7 columns"> <h3 class="feed__title feed__title--display"> <a href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" class="analytics t-edfooter-edpicks-1"> Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals </a> </h3> <p class="feed__description hide-small show-large">A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market.</p> <div class="secondary-label"> By Michael Gibney • <span class="secondary-label">Nov. 21, 2024</span> </div> </div> </li> </ul> </div> <div style="display: none;" id="inline-signup-html-desktop"> <div class="inline-signup"> <p class="inline-signup__copy">Keep up with the story. Subscribe to the PharmaVoice free daily newsletter</p> <form class="form js-form-email-validate" name="signup" action="/signup/" method="POST"> <label for="id_fefcd5_email" class="email-input js-email-input"> <span class="screen-reader-text">Email:</span> <input type="email" name="email" placeholder="Work email address" class="email" required id="id_fefcd5_email"> </label> <input type="hidden" name="signup_box_location" value="inline"> <input type="hidden" name="signup_initial_url_path" value="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <input type="hidden" name="js_enabled" value="0" id="id_fefcd5_js_enabled"> <ul class="signup-list list-no-bullets"> <li> <label><span class="screen-reader-text">Select user consent:</span></label> <input type="checkbox" name="user_consent" id="id_user_consent-inline" value="1" class="checkbox"/> <label for="id_user_consent-inline"> <span class="signup-user-consent_box"> <span> By signing up to receive our newsletter, you agree to our <a href="https://www.industrydive.com/terms-of-use/" target="_blank">Terms of Use</a> and <a href="https://www.industrydive.com/privacy-policy/" target="_blank">Privacy Policy</a>. You can unsubscribe at anytime. </span> </span> </label> </li> </ul> <button class="button button--medium signup-button" type="submit" value="Sign up">Sign up</button> <script type="module" src="/static/js/dist/sendEmailToLytics.bundle.js?520216211124" ></script> <label class="error email_error" style="display:none;">A valid email address is required.</label> <label class="error newsletter-error" style="display:none;">Please select at least one newsletter.</label> </form> </div> <div class="subscriber-demographics demographics-form" id="demographics-box-inline"></div> <script src="/static/js/subscriberDemographicsForm.js?302516180124"></script> <script> var siteName = 'PharmaVoice' || null; if (siteName) { setupFormCallbackAndCreateFormIfSub(siteName, 'inline'); } </script> </div> <script type="text/javascript"> $(document).ready(function () { // copy the contents of the generic_signup partial into the desktop_signup_spot $desktop_signup_spot = $("#desktop-inline-signup"); $desktop_signup = $("#inline-signup-html-desktop").children(); $desktop_signup_spot.append($desktop_signup); $("#inline-signup-html-desktop").remove(); }); </script> </section> <aside class="sidebar large-4 columns"> <div class="hybrid-ad-wrapper hide-small show-large"> <div class="hybrid-ad-inner-wrapper"> <div class="hide-small show-large"> <div data-container-ad-unit-id="/21662595662/pharmavoice/pharmavoicehybrid1-desktop"></div> <div id='dfp-hybrid1-desktop'> <script> waitToLoadAds.push(function() { googletag.cmd.push(function() { if (window.dfp_visibility == 'desktop' ) { googletag.display('dfp-hybrid1-desktop'); googletag.pubads().addEventListener('slotRenderEnded', function (event) { var adUnitPath = '/21662595662/pharmavoice/pharmavoicehybrid1'; var onProformative = false; if (onProformative && event.slot.getAdUnitPath() === adUnitPath && !event.isEmpty ) { var adUnitPathWithVisibility = adUnitPath + '-desktop'; var selector = '.pf-comments__ad-wrapper [data-container-ad-unit-id="' + adUnitPathWithVisibility + '"]'; if (!$(selector).closest('.pf-comments__ad-wrapper').hasClass('borders')) { $(selector).closest('.pf-comments__ad-wrapper').addClass('borders') } } }); } }); }); </script> </div> </div> </div> </div> <div class="signup sidebar-signup-box hide-small show-large" data-box-priority="0"> <h3 class="sidebar-signup-box__header">Get the free newsletter</h3> <p class="sidebar-signup-box__description">Subscribe to PharmaVoice for important stories, insights & perspectives</p> <form class="form js-form-email-validate" name="signup" action="/signup/" method="POST"> <label for="id_70c89e_email" class="email-input js-email-input"> <span class="screen-reader-text">Email:</span> <input type="email" name="email" placeholder="Work email address" class="email" required id="id_70c89e_email"> </label> <input type="hidden" name="signup_box_location" value="sidebar"> <input type="hidden" name="signup_initial_url_path" value="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <input type="hidden" name="js_enabled" value="0" id="id_70c89e_js_enabled"> <ul class="signup-list list-no-bullets"> <li> <label><span class="screen-reader-text">Select user consent:</span></label> <input type="checkbox" name="user_consent" id="id_user_consent-sidebar" value="1" class="checkbox"/> <label for="id_user_consent-sidebar"> <span class="signup-user-consent_box"> <span> By signing up to receive our newsletter, you agree to our <a href="https://www.industrydive.com/terms-of-use/" target="_blank">Terms of Use</a> and <a href="https://www.industrydive.com/privacy-policy/" target="_blank">Privacy Policy</a>. You can unsubscribe at anytime. </span> </span> </label> </li> </ul> <button class="button button--medium signup-button" type="submit" value="Sign up">Sign up</button> <script type="module" src="/static/js/dist/sendEmailToLytics.bundle.js?520216211124" ></script> <label class="error email_error" style="display:none;">A valid email address is required.</label> <label class="error newsletter-error" style="display:none;">Please select at least one newsletter.</label> </form> </div> <div class="subscriber-demographics demographics-form" id="demographics-box-sidebar"></div> <script src="/static/js/subscriberDemographicsForm.js?302516180124"></script> <script> var siteName = 'PharmaVoice' || null; if (siteName) { setupFormCallbackAndCreateFormIfSub(siteName, 'sidebar'); } </script> <div class="sidebar-box" data-box-priority="2"> <h3 class="sidebar-box__header sidebar-box__header--loud"> Most Popular </h3> <ol class="sidebar-box-list sidebar-box-list--ordered"> <li class="sidebar-box-list__item sidebar-box-list__item--ordered flex">  <div class="sidebar-box-list__image-container"> <a class="analytics t-most-popular-sidebar-item-1 hide-small show-large" href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <img class="sidebar-box-list__image" src="https://imgproxy.divecdn.com/BX2oEajr6CixdvcJc8r_UPcRDAUh7M5Fcs0NsF7X138/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/oxID8_bFYzrMfwQpy92VUm-83IfASezf74akk90ck_Q/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 300w, https://imgproxy.divecdn.com/BX2oEajr6CixdvcJc8r_UPcRDAUh7M5Fcs0NsF7X138/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 600w" sizes="25vw" alt="Keytruda, Merck" loading="lazy" > </a> </div> <div class="sidebar-box-title-container"> <a class="analytics t-most-popular-sidebar-item-1 sidebar-box-list__item-title" href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/">Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals </a>  </div> </li> <li class="sidebar-box-list__item sidebar-box-list__item--ordered flex">  <div class="sidebar-box-list__image-container"> <a class="analytics t-most-popular-sidebar-item-2 hide-small show-large" href="/news/walgreens-earnings-clinical-trials-ramita-tandon/733660/"> <img class="sidebar-box-list__image" src="https://imgproxy.divecdn.com/Gbrtg5rb4Sge4DZEzdgElw6oFchVVwFYHY5JkfKMJFg/g:nowe:0:0/c:1024:578/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xOTA3NzI4Mzk0X1pPcElvNkEuanBn.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/DUZfh12_gUeYh8WzTWsHv2nOY8Nk2dw_udawPwtV9nk/g:nowe:0:0/c:1024:578/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xOTA3NzI4Mzk0X1pPcElvNkEuanBn.webp 300w, https://imgproxy.divecdn.com/Gbrtg5rb4Sge4DZEzdgElw6oFchVVwFYHY5JkfKMJFg/g:nowe:0:0/c:1024:578/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xOTA3NzI4Mzk0X1pPcElvNkEuanBn.webp 600w" sizes="25vw" alt="Walgreens pharmacy" loading="lazy" > </a> </div> <div class="sidebar-box-title-container"> <a class="analytics t-most-popular-sidebar-item-2 sidebar-box-list__item-title" href="/news/walgreens-earnings-clinical-trials-ramita-tandon/733660/">Will Walgreens’ store closures derail its clinical trial aims? </a>  </div> </li> <li class="sidebar-box-list__item sidebar-box-list__item--ordered flex">  <div class="sidebar-box-list__image-container"> <a class="analytics t-most-popular-sidebar-item-3 hide-small show-large" href="/news/big-pharma-campaign-election-pac-donations/731124/"> <img class="sidebar-box-list__image" src="https://imgproxy.divecdn.com/HXvTYHK980NdtqnBERMhX3v2WTV3JB0EzkSMf21MLic/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy05Njc4MzM1NzQuanBn.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/8hMpujNlEhW_lV6sEKiGcbBqA1io3KbVkB9-e5gz8xY/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy05Njc4MzM1NzQuanBn.webp 300w, https://imgproxy.divecdn.com/HXvTYHK980NdtqnBERMhX3v2WTV3JB0EzkSMf21MLic/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy05Njc4MzM1NzQuanBn.webp 600w" sizes="25vw" alt="three people stand behind voting booths" loading="lazy" > </a> </div> <div class="sidebar-box-title-container"> <a class="analytics t-most-popular-sidebar-item-3 sidebar-box-list__item-title" href="/news/big-pharma-campaign-election-pac-donations/731124/">Where Big Pharma’s campaign cash is flowing in this election </a>  </div> </li> <li class="sidebar-box-list__item sidebar-box-list__item--ordered flex">  <div class="sidebar-box-list__image-container"> <a class="analytics t-most-popular-sidebar-item-4 hide-small show-large" href="/news/pfizer-chris-boshoff-research-development-dolsten-successor/733488/"> <img class="sidebar-box-list__image" src="https://imgproxy.divecdn.com/iczVVX7gsNDTvXpLPxuKwPAs7OLcnrwuvv0HH8QxN5E/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDkxNDg0MDMxLmpwZw==.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/AE7pPRrxXww4UexZm0mKYXaX6sOtUX4jvFQ3dprS50A/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDkxNDg0MDMxLmpwZw==.webp 300w, https://imgproxy.divecdn.com/iczVVX7gsNDTvXpLPxuKwPAs7OLcnrwuvv0HH8QxN5E/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDkxNDg0MDMxLmpwZw==.webp 600w" sizes="25vw" alt="People pass an office building with signage spelling Pfizer in New York City." loading="lazy" > </a> </div> <div class="sidebar-box-title-container"> <a class="analytics t-most-popular-sidebar-item-4 sidebar-box-list__item-title" href="/news/pfizer-chris-boshoff-research-development-dolsten-successor/733488/">Pfizer, under pressure to change, names oncology head as new R&D chief </a>  </div> </li> </ol> </div> <div class="sidebar-box hide-small show-large" data-box-priority="4"> <h3 class="sidebar-box__header">Library resources</h3> <ul class="sidebar-box-list"> <li class="sidebar-box-list__item flex"> <div class='sidebar-box-list__icon sidebar-box-list__icon--loud'> <img src="/static/img/lib_icons/webinar.svg?102717100918" height="25" width="25" alt="editorial resource icon" loading="lazy"> </div> <div> <div class="label label--soft">Virtual Event Playback</div> <a class="analytics t-library-sidebar-item-1 sidebar-box-list__item-title" target="_blank" href="https://events.industrydive.com/events/biotechs-new-normal?utm_source=PV&utm_medium=Library&utm_campaign=Q42024BioPharmaDiveLive"> Biotech’s New Normal Challenges and Opportunities </a> </div> </li> <li class="sidebar-box-list__item flex"> <div class='sidebar-box-list__icon sidebar-box-list__icon--soft'> <img src="/static/img/lib_icons/playbook-black.svg?141716111021" height="25" width="25" alt="studioID resource icon" loading="lazy"> </div> <div> <div class="label label--soft">Playbook</div> <a class="analytics t-library-sidebar-item-2 sidebar-box-list__item-title" target="_blank" href="https://biopharmadive.tradepub.com/c/pubRD.mpl?secure=1&sr=pp&_t=pp%3A&qf=w_defa6449&ch=Library&utm_source=PV&utm_medium=Library&utm_campaign=VisibleAlpha"> Data Tools Revolutionizing Pharmaceutical Financial Analysis </a> <span class="sponsor-label__leading-text secondary-label">Custom content for </span> <span class="sponsor-label__name secondary-label">Visible Alpha</span> </div> </li> <li class="sidebar-box-list__item flex"> <div class='sidebar-box-list__icon sidebar-box-list__icon--soft'> <img src="/static/img/lib_icons/playbook-black.svg?141716111021" height="25" width="25" alt="studioID resource icon" loading="lazy"> </div> <div> <div class="label label--soft">Playbook</div> <a class="analytics t-library-sidebar-item-3 sidebar-box-list__item-title" target="_blank" href="https://biopharmadive.tradepub.com/c/pubRD.mpl?secure=1&sr=pp&_t=pp:&qf=w_defa7427&ch=Library&utm_source=PV&utm_medium=Library&utm_campaign=WCG"> Clinical Trials in EMEA: How to Navigate Geographical Nuances </a> <span class="sponsor-label__leading-text secondary-label">Custom content for </span> <span class="sponsor-label__name secondary-label">WCG</span> </div> </li> </ul> <a class="analytics t-library-sidebar-all sidebar-box__cta" aria-label="View all library items" href="/library/">View all</a> </div> <div class="sidebar-box js-pressrelease-sidebar-box" data-box-priority=" 6 "> <h3 class="sidebar-box__header">Company Announcements</h3> <ul class="sidebar-box-list"> <li class="sidebar-box-list__item flex js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241113-new-medable-ai-capabilities-simplifies-digital-clinical-trial-launch-with-i/"> <div class="sidebar-box-list__thumbnail-container"> <img alt="Medable logo" height="48" loading="lazy" src="https://res.cloudinary.com/dmgi9movl/image/upload/dpr_2.0,h_48,w_48/v1731514782/press_release/assets/company_logos/Medable_Logo_rwxzmx.png" width="48"/> </div> <div class="sidebar-box-title-container"> <a class="sidebar-box-list__item-title analytics t-pr-sidebar-item" href="/press-release/20241113-new-medable-ai-capabilities-simplifies-digital-clinical-trial-launch-with-i/">New Medable AI Capabilities Simplifies Digital Clinical Trial Launch with Instant eCOA Generat…</a> <span class="secondary-label"> From Medable </span> </div> </li> <li class="sidebar-box-list__item flex js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241122-from-molecule-to-market-and-beyond-uniphar-announces-extended-global-comme-1/"> <div class="sidebar-box-list__thumbnail-container"> <img alt="Uniphar logo" height="48" loading="lazy" src="https://res.cloudinary.com/dmgi9movl/image/upload/dpr_2.0,h_48,w_48/v1732277681/press_release/assets/company_logos/Uniphar_Logo_lj0uh5.png" width="48"/> </div> <div class="sidebar-box-title-container"> <a class="sidebar-box-list__item-title analytics t-pr-sidebar-item" href="/press-release/20241122-from-molecule-to-market-and-beyond-uniphar-announces-extended-global-comme-1/">From molecule to market and beyond: Uniphar announces extended global commercialization platfo…</a> <span class="secondary-label"> From Uniphar </span> </div> </li> <li class="sidebar-box-list__item flex js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241114-trialassure-wins-prestigious-michbusiness-triple-trusted-advisors-award-for/"> <div class="sidebar-box-list__thumbnail-container"> <img alt="TrialAssure logo" height="48" loading="lazy" src="https://res.cloudinary.com/dmgi9movl/image/upload/dpr_2.0,h_48,w_48/v1731603293/press_release/assets/company_logos/TrialAssure_Logo_2024_Update_TrialAssure_Tagline_FullColor_No_TM_lbxsaj.png" width="48"/> </div> <div class="sidebar-box-title-container"> <a class="sidebar-box-list__item-title analytics t-pr-sidebar-item" href="/press-release/20241114-trialassure-wins-prestigious-michbusiness-triple-trusted-advisors-award-for/">TrialAssure Wins Prestigious MichBusiness Triple Trusted Advisors Award for its Innovative AI …</a> <span class="secondary-label"> From TrialAssure </span> </div> </li> <li class="sidebar-box-list__item flex js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241106-catalyx-and-inel-forge-strategic-partnership-to-advance-packaging-automatio-1/"> <div class="sidebar-box-title-container"> <a class="sidebar-box-list__item-title analytics t-pr-sidebar-item" href="/press-release/20241106-catalyx-and-inel-forge-strategic-partnership-to-advance-packaging-automatio-1/">CATALYX AND INEL FORGE STRATEGIC PARTNERSHIP TO ADVANCE PACKAGING AUTOMATION IN PHARMACEUTICAL…</a> <span class="secondary-label"> From Catalyx </span> </div> </li> </ul> <span class="sidebar-box__cta"> <a class="analytics t-pr-sidebar-all" aria-label="View all press release items" href="/press-release/">View all</a> | <a class="analytics t-pr-sidebar-start" href="/press-release/get-started/">Post a press release</a> </span> </div> <div class="sidebar-box hide-small show-large" data-box-priority="10"> <h3 class="sidebar-box__header">Events</h3> <ul class="sidebar-box-list"> <li class="sidebar-box-list__item flex"> <div class="sidebar-box-list__events-date "> <span class="sidebar-box-list__events-date__day "> 08 </span> <span class="sidebar-box-list__events-date__month "> APR </span> </div> <div class="sidebar-box-title-container__events"> <span class="label label--soft"> Conference </span> <a class="analytics t-events-sidebar-item sidebar-box-list__item-title sidebar-box-list__item-title--spaced" href="https://medicaldeviceregulatoryaffairs.com/" target="_blank" rel="noopener noreferrer">European Medical Device & Diagnostic Regulatory Affairs Conference </a> <span class="label label--weak">Brussels, Belgium </span><br> <span class="label label--weak-italic">Presented by TT Lifesciences</span> </div> </li> </ul> <div class="sidebar-box__cta"> <a class="analytics t-events-sidebar-start " href="/selfservice/event-listings/contact">Promote an event</a> </div> </div> <div class="hybrid-ad-wrapper hide-small show-large"> <div class="hybrid-ad-inner-wrapper"> <div class="hide-small show-large"> <div data-container-ad-unit-id="/21662595662/pharmavoice/pharmavoicehybrid3-desktop"></div> <div id='dfp-hybrid3-desktop'> <script> waitToLoadAds.push(function() { googletag.cmd.push(function() { if (window.dfp_visibility == 'desktop' ) { googletag.display('dfp-hybrid3-desktop'); googletag.pubads().addEventListener('slotRenderEnded', function (event) { var adUnitPath = '/21662595662/pharmavoice/pharmavoicehybrid3'; var onProformative = false; if (onProformative && event.slot.getAdUnitPath() === adUnitPath && !event.isEmpty ) { var adUnitPathWithVisibility = adUnitPath + '-desktop'; var selector = '.pf-comments__ad-wrapper [data-container-ad-unit-id="' + adUnitPathWithVisibility + '"]'; if (!$(selector).closest('.pf-comments__ad-wrapper').hasClass('borders')) { $(selector).closest('.pf-comments__ad-wrapper').addClass('borders') } } }); } }); }); </script> </div> </div> </div> </div> </aside> </div> </div> </div>  <section class="pre-footer"> <section class="signup call-out elevated-footer hide-small hide-medium show-large"> <div class="row"> <div class="large-11 medium-11 medium-centered columns footer-signup" style="display: flex"> <div class="footer-signup__content"> <h3>PharmaVoice stories and insights delivered to your inbox</h3> <p class="subhead">Get the free daily newsletter read by industry leaders</p> <form class="form js-form-email-validate" name="signup" action="/signup/" method="POST"> <label for="id_132730_email" class="email-input js-email-input"> <span class="screen-reader-text">Email:</span> <input type="email" name="email" placeholder="Work email address" class="email" required id="id_132730_email"> </label> <input type="hidden" name="signup_box_location" value="elevated_footer"> <input type="hidden" name="signup_initial_url_path" value="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <input type="hidden" name="js_enabled" value="0" id="id_132730_js_enabled"> <ul class="signup-list list-no-bullets"> <li> <label><span class="screen-reader-text">Select user consent:</span></label> <input type="checkbox" name="user_consent" id="id_user_consent-elevated_footer" value="1" class="checkbox"/> <label for="id_user_consent-elevated_footer"> <span class="signup-user-consent_box"> <span> By signing up to receive our newsletter, you agree to our <a href="https://www.industrydive.com/terms-of-use/" target="_blank">Terms of Use</a> and <a href="https://www.industrydive.com/privacy-policy/" target="_blank">Privacy Policy</a>. You can unsubscribe at anytime. </span> </span> </label> </li> </ul> <button class="button button--medium signup-button" type="submit" value="Sign up">Sign up</button> <script type="module" src="/static/js/dist/sendEmailToLytics.bundle.js?520216211124" ></script> <label class="error email_error" style="display:none;">A valid email address is required.</label> <label class="error newsletter-error" style="display:none;">Please select at least one newsletter.</label> </form> </div> <div class="footer-signup__image"> <img class="desktop-image" src="/static/img/pharmavoice/signup-article.png?080016020822" width="275" height="275" loading="lazy" alt="PharmaVoice newsletter example"> </div> </div> </div> </section> <section class="hide-small hide-medium show-large pressrelease-section"> <div class="row pressrelease-footer-box js-pressrelease-footer-box"> <div class="large-12 columns"> <div class="row"> <div class="large-12 columns pressrelease-footer-header"> <h2 class="uppercase-heading-02 pressrelease-footer__heading">Company Announcements</h2> </div> </div> <div class="row"> <div class="large-12 columns pressrelease-footer__cta-links"> <a class="analytics t-pr-edfooter-all" aria-label="View all press release items" href="/press-release/">View all</a> | <a class="analytics t-pr-edfooter-start" href="/press-release/get-started/">Post a press release</a> </div> </div> <div class="row pressrelease-footer__item-list"> <a class="pressrelease-footer-item__anchor analytics t-pr-edfooter-item" href="/press-release/20241113-new-medable-ai-capabilities-simplifies-digital-clinical-trial-launch-with-i/"> <div class="large-3 columns pressrelease-footer-item js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241113-new-medable-ai-capabilities-simplifies-digital-clinical-trial-launch-with-i/"> <div class="pressrelease-footer-item__title"> New Medable AI Capabilities Simplifies Digital Clinical Trial Launch with Instant eCOA Generat… </div> <div class="pressrelease-footer-item__description"> <div class="pressrelease-footer-item__company"> <div>From Medable</div> <div class="press-release-date">November 13, 2024</div> </div> <span> <img alt="Medable logo" class="pressrelease-footer-item__logo" height="50" loading="lazy" src="https://res.cloudinary.com/dmgi9movl/image/upload/dpr_2.0,h_50,w_50/v1731514782/press_release/assets/company_logos/Medable_Logo_rwxzmx.png" width="50"/> </span> </div> </div> </a> <a class="pressrelease-footer-item__anchor analytics t-pr-edfooter-item" href="/press-release/20241122-from-molecule-to-market-and-beyond-uniphar-announces-extended-global-comme-1/"> <div class="large-3 columns pressrelease-footer-item js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241122-from-molecule-to-market-and-beyond-uniphar-announces-extended-global-comme-1/"> <div class="pressrelease-footer-item__title"> From molecule to market and beyond: Uniphar announces extended global commercialization platfo… </div> <div class="pressrelease-footer-item__description"> <div class="pressrelease-footer-item__company"> <div>From Uniphar</div> <div class="press-release-date">November 22, 2024</div> </div> <span> <img alt="Uniphar logo" class="pressrelease-footer-item__logo" height="50" loading="lazy" src="https://res.cloudinary.com/dmgi9movl/image/upload/dpr_2.0,h_50,w_50/v1732277681/press_release/assets/company_logos/Uniphar_Logo_lj0uh5.png" width="50"/> </span> </div> </div> </a> <a class="pressrelease-footer-item__anchor analytics t-pr-edfooter-item" href="/press-release/20241114-trialassure-wins-prestigious-michbusiness-triple-trusted-advisors-award-for/"> <div class="large-3 columns pressrelease-footer-item js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241114-trialassure-wins-prestigious-michbusiness-triple-trusted-advisors-award-for/"> <div class="pressrelease-footer-item__title"> TrialAssure Wins Prestigious MichBusiness Triple Trusted Advisors Award for its Innovative AI … </div> <div class="pressrelease-footer-item__description"> <div class="pressrelease-footer-item__company"> <div>From TrialAssure</div> <div class="press-release-date">November 14, 2024</div> </div> <span> <img alt="TrialAssure logo" class="pressrelease-footer-item__logo" height="50" loading="lazy" src="https://res.cloudinary.com/dmgi9movl/image/upload/dpr_2.0,h_50,w_50/v1731603293/press_release/assets/company_logos/TrialAssure_Logo_2024_Update_TrialAssure_Tagline_FullColor_No_TM_lbxsaj.png" width="50"/> </span> </div> </div> </a> <a class="pressrelease-footer-item__anchor analytics t-pr-edfooter-item" href="/press-release/20241106-catalyx-and-inel-forge-strategic-partnership-to-advance-packaging-automatio-1/"> <div class="large-3 columns pressrelease-footer-item js-pressrelease" data-pressrelease-full-url="https://www.pharmavoice.com/press-release/20241106-catalyx-and-inel-forge-strategic-partnership-to-advance-packaging-automatio-1/"> <div class="pressrelease-footer-item__title"> CATALYX AND INEL FORGE STRATEGIC PARTNERSHIP TO ADVANCE PACKAGING AUTOMATION IN PHARMACEUTICAL… </div> <div class="pressrelease-footer-item__description"> <div class="pressrelease-footer-item__company"> <div>From Catalyx</div> <div class="press-release-date">November 06, 2024</div> </div> </div> </div> </a> </div> </div> </div> </section> <div class="row editors-pick-footer hide-small show-large"> <div class="columns medium-7"> <div class="row"> <div class="columns medium-12"> <div class="editors-pick-footer__title"> Read next </div> <ul class="feed"> <li class="row feed__item"> <div class="medium-5 columns"> <figure class="feed__image-container"> <a class="feed__image analytics t-edfooter-edpicks-1" href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <img class="" src="https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" width="1200" height="675" srcset="https://imgproxy.divecdn.com/oxID8_bFYzrMfwQpy92VUm-83IfASezf74akk90ck_Q/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 300w, https://imgproxy.divecdn.com/BX2oEajr6CixdvcJc8r_UPcRDAUh7M5Fcs0NsF7X138/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 600w, https://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 1200w" sizes="(min-width: 40em ) 25vw, 100vw" alt="Keytruda, Merck" loading="lazy" > </a> <figcaption> <img class="feed__attribution-icon" src="/static/images/info-icon.png?234917240220" width="16" height="16" alt="Image attribution tooltip" tabindex="0"> <div class="feed__attribution">Permission granted by Merck & Co.</div> <img class="feed__attribution-icon" src="/static/images/info-icon.png?234917240220" width="16" height="16" alt="Image attribution tooltip" tabindex="-1"> </figcaption> </figure> </div> <div class="medium-7 columns"> <h3 class="feed__title feed__title--display"> <a href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" class="analytics t-edfooter-edpicks-1"> Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals </a> </h3> <p class="feed__description hide-small show-large">A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market.</p> <div class="secondary-label"> By Michael Gibney • <span class="secondary-label">Nov. 21, 2024</span> </div> </div> </li> </ul> </div> </div> </div> <div class="columns medium-4"> <div class="row newsposts-by-topic"> <div class="columns medium-12"> <div class="editors-pick-footer__title"> Latest in Pharma </div> <div class="newsposts-by-topic-section"> <ul class="feed"> <li class="row feed__item"> <div class="medium-4 columns"> <div class="feed__image-container"> <a class="feed__image analytics t-edfooter-topics-1" href="/news/walgreens-earnings-clinical-trials-ramita-tandon/733660/"> <img class="" src="https://imgproxy.divecdn.com/Gbrtg5rb4Sge4DZEzdgElw6oFchVVwFYHY5JkfKMJFg/g:nowe:0:0/c:1024:578/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xOTA3NzI4Mzk0X1pPcElvNkEuanBn.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/DUZfh12_gUeYh8WzTWsHv2nOY8Nk2dw_udawPwtV9nk/g:nowe:0:0/c:1024:578/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xOTA3NzI4Mzk0X1pPcElvNkEuanBn.webp 300w, https://imgproxy.divecdn.com/Gbrtg5rb4Sge4DZEzdgElw6oFchVVwFYHY5JkfKMJFg/g:nowe:0:0/c:1024:578/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xOTA3NzI4Mzk0X1pPcElvNkEuanBn.webp 600w" sizes="25vw" alt="Walgreens pharmacy" loading="lazy" > </a> </div> </div> <div class="medium-8 columns latest-copy"> <div class="display-heading-01"> <a class="analytics t-edfooter-topics-1" href="/news/walgreens-earnings-clinical-trials-ramita-tandon/733660/"> Will Walgreens’ store closures derail its clinical trial aims? </a> </div> <div class="secondary-label"> By Meagan Parrish </div> </div> </li> <li class="row feed__item"> <div class="medium-4 columns"> <div class="feed__image-container"> <a class="feed__image analytics t-edfooter-topics-2" href="/news/pfizer-chris-boshoff-research-development-dolsten-successor/733488/"> <img class="" src="https://imgproxy.divecdn.com/iczVVX7gsNDTvXpLPxuKwPAs7OLcnrwuvv0HH8QxN5E/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDkxNDg0MDMxLmpwZw==.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/AE7pPRrxXww4UexZm0mKYXaX6sOtUX4jvFQ3dprS50A/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDkxNDg0MDMxLmpwZw==.webp 300w, https://imgproxy.divecdn.com/iczVVX7gsNDTvXpLPxuKwPAs7OLcnrwuvv0HH8QxN5E/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDkxNDg0MDMxLmpwZw==.webp 600w" sizes="25vw" alt="People pass an office building with signage spelling Pfizer in New York City." loading="lazy" > </a> </div> </div> <div class="medium-8 columns latest-copy"> <div class="display-heading-01"> <a class="analytics t-edfooter-topics-2" href="/news/pfizer-chris-boshoff-research-development-dolsten-successor/733488/"> Pfizer, under pressure to change, names oncology head as new R&D chief </a> </div> <div class="secondary-label"> By Kristin Jensen </div> </div> </li> <li class="row feed__item"> <div class="medium-4 columns"> <div class="feed__image-container"> <a class="feed__image analytics t-edfooter-topics-3" href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <img class="" src="https://imgproxy.divecdn.com/BX2oEajr6CixdvcJc8r_UPcRDAUh7M5Fcs0NsF7X138/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" width="600" height="338" srcset="https://imgproxy.divecdn.com/oxID8_bFYzrMfwQpy92VUm-83IfASezf74akk90ck_Q/g:ce/rs:fill:300:169:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 300w, https://imgproxy.divecdn.com/BX2oEajr6CixdvcJc8r_UPcRDAUh7M5Fcs0NsF7X138/g:ce/rs:fill:600:338:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp 600w" sizes="25vw" alt="Keytruda, Merck" loading="lazy" > </a> </div> </div> <div class="medium-8 columns latest-copy"> <div class="display-heading-01"> <a class="analytics t-edfooter-topics-3" href="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals </a> </div> <div class="secondary-label"> By Michael Gibney </div> </div> </li> </ul> </div> </div> </div> </div> </div> </section> <hr class="footer-hr"> <footer> <div class="custom-article-footer"> <div class="row columns"> <div class="footer-grid"> <div class="footer-links"> <a href="https://www.industrydive.com"> <img class="pub-logo-footer" src="https://d12v9rtnomnebu.cloudfront.net/logo/corporate/ID_black.svg" alt="Industry Dive Logo" height="28" loading="lazy"/> </a> <ul class="social-icon-list social-icon-list__footer"> <li> <a href="https://www.linkedin.com/company/pharmavoice" aria-label="Industry Dive LinkedIn" class="social-icon-footer analytics t-sitefooter-linkedin"> <img src="/static/img/social_icons/article_page/linkedin.svg?092716141024"> </a> </li> <li> <a href="https://www.facebook.com/PharmaVoice" aria-label="Industry Dive Facebook" class="social-icon-footer analytics t-sitefooter-facebook"> <img src="/static/img/social_icons/article_page/facebook.svg?440116200824"> </a> </li> <li> <a href="https://twitter.com/PharmaVoice" aria-label="Industry Dive X/Twitter" class="social-icon-footer analytics t-sitefooter-twitter"> <img src="/static/img/social_icons/article_page/x.svg?092716141024"> </a> </li> <li> <a href="https://www.pharmavoice.com/feeds/news/" aria-label="Industry Dive RSS feed" class="social-icon-footer analytics t-sitefooter-rss"> <img src="/static/img/social_icons/article_page/rss.svg?440116200824"> </a> </li> </ul> </div> <div class="link-wrapper"> <div class="footer-links"> <h4 class="uppercase-heading-01">Explore</h4> <ul class="list-no-bullets"> <li> <a href="/about/" class="analytics t-about-sitefooter">About</a> </li> <li> <a href="/editors/" class="analytics t-editors-sitefooter">Editorial Team</a> </li> <li> <a href="/contact/" class="analytics t-feedback-sitefooter">Contact Us</a> </li> <li> <a href="/signup/?signup_location=footer-list&signup_path=/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/" class="analytics t-signup-sitefooter">Newsletter</a> </li> <li> <a href="/selfservice/article-licensing/submit/" class="analytics t-licensing-sitefooter">Purchase Licensing Rights</a> </li> <li> <a class="analytics t-pr-sitefooter-all" href="/press-release/">Press Releases</a> </li> </ul> </div> <div class="second-column"> <div class="footer-links"> <h4 class="uppercase-heading-01">Reach our audience</h4> <ul class="list-no-bullets"> <li> <a href="/advertise/" class="analytics t-advertising-sitefooter">Advertising</a> </li> <li> <a class="analytics t-pr-sitefooter-all" href="/press-release/get-started/">Post a press release</a> </li> <li> <a class="analytics t-events-sitefooter-start" href="/selfservice/event-listings/contact">Promote an event</a> </li> </ul> </div> <div class="footer-links"> </div> </div> </div> </div> </div> </div> </footer> <hr class="footer-hr"> <div class="baseline-footer-wrapper"> <div class="informa-brand">  <svg id="SVGRoot" width="500" height="162" version="1.1" viewBox="0 0 500 162" xmlns="http://www.w3.org/2000/svg" xmlns:cc="http://creativecommons.org/ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:xlink="http://www.w3.org/1999/xlink"> <defs> <linearGradient id="linearGradient20775" x1="-24.025" x2="19.204" y1="-161.85" y2="-207.91" gradientTransform="matrix(1.4283 0 0 1.4283 268.58 476.51)" gradientUnits="userSpaceOnUse"> <stop stop-color="#061d41" offset="0"></stop> <stop stop-color="#061d42" stop-opacity=".6549" offset=".232"></stop> <stop stop-color="#051d40" stop-opacity=".56078" offset=".41621"></stop> <stop stop-color="#061c40" stop-opacity=".49804" offset=".61283"></stop> <stop stop-color="#061c40" stop-opacity=".35686" offset=".73858"></stop> <stop stop-color="#051f3e" stop-opacity=".19216" offset=".84133"></stop> <stop stop-color="#002449" stop-opacity=".054902" offset=".92525"></stop> <stop stop-color="#002449" stop-opacity=".054902" offset="1"></stop> </linearGradient> <linearGradient id="linearGradient20795" x1="-4.8824" x2="58.082" y1="-141.2" y2="-141.2" gradientTransform="matrix(1.4283 0 0 1.4283 268.6 476.54)" gradientUnits="userSpaceOnUse"> <stop stop-color="#061d41" offset="0"></stop> <stop stop-color="#223358" stop-opacity=".85098" offset=".098161"></stop> <stop stop-color="#3b486e" stop-opacity=".55686" offset=".18261"></stop> <stop stop-color="#535d82" stop-opacity=".4" offset=".26261"></stop> <stop stop-color="#656e8e" stop-opacity=".31765" offset=".33879"></stop> <stop stop-color="#77819f" stop-opacity=".21569" offset=".40636"></stop> <stop stop-color="#79809f" stop-opacity=".26275" offset=".46157"></stop> <stop stop-color="#495478" stop-opacity=".54902" offset=".5371"></stop> <stop stop-color="#26365c" stop-opacity=".66667" offset=".6699"></stop> <stop stop-color="#26375b" stop-opacity=".76863" offset=".80174"></stop> <stop stop-color="#13264b" stop-opacity=".9098" offset=".88553"></stop> <stop stop-color="#061d41" offset="1"></stop> </linearGradient> <linearGradient id="linearGradient20785" x1="10.56" x2="51.569" y1="-165.47" y2="-148.21" gradientTransform="matrix(1.4283 0 0 1.4283 268.58 476.51)" gradientUnits="userSpaceOnUse"> <stop stop-color="#061d41" offset="0"></stop> <stop stop-color="#061d42" stop-opacity=".6549" offset=".1618"></stop> <stop stop-color="#051d40" stop-opacity=".56078" offset=".34338"></stop> <stop stop-color="#061c40" stop-opacity=".49804" offset=".54217"></stop> <stop stop-color="#061c40" stop-opacity=".35686" offset=".66063"></stop> <stop stop-color="#051f3e" stop-opacity=".19216" offset=".78691"></stop> <stop stop-color="#002449" stop-opacity=".054902" offset=".89046"></stop> <stop stop-color="#002449" stop-opacity=".054902" offset="1"></stop> </linearGradient> </defs> <metadata> <rdf:rdf> <cc:work rdf:about=""> <dc:format>image/svg+xml</dc:format> <dc:type rdf:resource="http://purl.org/dc/dcmitype/StillImage"></dc:type> <dc:title></dc:title> </cc:work> </rdf:rdf> </metadata> <g transform="translate(-226.26 -174.1)"> <g fill="#061d41"> <path d="m433.38 241.62c-3.5038 0-6.3829-2.822-6.3829-6.3791s2.8792-6.3829 6.3829-6.3829 6.3791 2.8258 6.3791 6.3829-2.8754 6.3791-6.3791 6.3791m5.9945 50.686h-11.951v-46.269h11.951z"> </path> <path d="m477.3 292.31v-27.958c0-5.0614-0.5408-10.485-6.7371-10.485-3.4162 0-7.9101 1.4662-10.968 3.2143v35.228h-11.947v-46.265h11.947v4.6044c4.1398-3.0353 10.694-6.0706 15.816-6.0706 9.6163 0 13.836 7.1675 13.836 16.281v31.45z"> </path> <path d="m601.54 254.52c-3.5152 0.35038-7.2893 2.3003-10.344 4.0446v33.743h-11.951v-46.261h11.951v5.507c4.1321-3.0353 10.69-5.507 15.813-5.507v8.687s-2.9782-0.46083-5.4689-0.21328"> </path> <path d="m549.89 293.5c-15.276 0-23.452-9.4754-23.452-24.835 0-15.542 8.1767-24.096 23.452-24.096 14.822 0 23.452 9.0146 23.452 24.096 0 15.451-8.0853 24.835-23.452 24.835m0-40.655c-8.7175 0-11.593 8.4661-11.593 16.003 0 7.5445 2.6088 16.925 11.593 16.925 9.0793 0 11.68-9.2887 11.68-16.925 0-7.5369-2.963-16.003-11.68-16.003"> </path> <path d="m669.05 292.31v-27.958c0-5.1528-1.0816-10.485-7.1903-10.485-3.142 0-6.6457 1.4662-9.3421 3.2143 0.27039 1.1997 0.35799 2.4869 0.35799 3.778v31.45h-11.947v-27.958c0-5.0614-0.62838-10.485-6.8285-10.485-3.0582 0-6.8323 1.4662-9.3497 3.2143v35.228h-11.951v-46.265h11.951v4.6044c3.778-3.0353 9.9819-6.0706 14.735-6.0706 5.1262 0 9.1669 2.1099 11.505 6.8971 4.3149-2.9439 10.964-6.8971 16.174-6.8971 9.7039 0 13.836 7.1675 13.836 16.281v31.45z"> </path> <path d="m715.48 285.5c-3.2334 4.5054-9.2545 8.0015-14.735 8.0015-7.4569 0-13.84-5.0614-13.84-13.059 0-15.085 16.353-16.829 27.767-17.29v-2.7611c0-5.2404-4.2236-7.9063-9.0755-7.9063-4.4901 0-9.3421 0.63981-13.661 2.1137v-5.149c4.8557-3.0391 10.336-4.8748 16.087-4.8748 8.9841 0 18.239 3.9531 18.239 14.533v33.198h-10.782zm-16.982-6.8018c0 4.1398 2.6088 7.0761 6.6495 7.0761 5.0309 0 9.5249-4.3188 9.5249-9.563v-6.6228c-5.3013 0.28182-16.174 2.2089-16.174 9.1098"> </path> <path d="m520.32 236.2c1.5043 0 3.0658 0.14472 4.5815 0.36942v-5.2975c-2.9744-1.5538-6.2572-2.525-9.6125-2.525-10.606 0-15.001 7.3579-15.001 17.294h-5.5146v8.0548h5.5146l0.0876 38.206h12.035v-38.206h12.492v-8.0548h-12.579c0-5.8878 1.3482-9.841 7.9977-9.841"> </path> </g> <g fill="#061d41" fill-rule="evenodd" shape-rendering="auto"> <path d="m381.26 248.68c-2.4473 5.7e-4 -4.5519 1.4664-5.4845 3.568-0.38853 1.002-0.5029 1.8671-0.50214 2.798 1e-3 1.4426-0.0436 2.876-0.13391 4.2961-2.2793 35.836-31.958 64.081-68.38 64.081-37.915 0-68.523-30.608-68.523-68.523 0-1.6651 0.0792-3.3112 0.19528-4.9461h-12.007c-0.0999 1.6378-0.16738 3.2836-0.16738 4.9461 1e-5 44.387 36.114 80.499 80.501 80.499 42.933 0 78.125-33.783 80.384-76.164 0.0765-1.4352 0.0818-2.8815 0.11438-4.3352 0.0166-0.73955-0.17802-1.5025-0.30408-2.1229-0.79532-2.3817-3.0446-4.0986-5.6937-4.098z" color="#000000" color-rendering="auto" image-rendering="auto" style="font-feature-settings:normal;font-variant-alternates:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-position:normal;isolation:auto;mix-blend-mode:normal;shape-padding:0;text-decoration-color:#000000;text-decoration-line:none;text-decoration-style:solid;text-indent:0;text-orientation:mixed;text-transform:none;white-space:normal"> </path> <path d="m306.7 197.44c-0.88702-4.9e-4 -1.7724 0.34162-2.4884 0.59142-1.6476 0.85112-2.766 2.5696-2.7646 4.536 1e-3 1.7596 0.89642 3.3156 2.2624 4.2319 1.0349 0.56984 1.9875 0.91995 2.9905 0.92338 26.184 0.0893 47.302 21.117 47.302 47.302 0 1.5398-0.073 3.0621-0.21587 4.5636l10.251 0.79182c0.16357-1.7636 0.2472-3.5499 0.2472-5.3554 0-31.742-25.842-57.567-57.584-57.584zm-52.471 52.105c-2.4386-6.7e-4 -4.4709 1.6825-4.9851 3.9669-0.12083 0.53679-0.12789 1.0361-0.12832 1.512-5e-3 5.2759 0.70622 10.388 2.0408 15.246l10.155-1.9255c-1.2353-4.2224-1.9022-8.692-1.9127-13.32-2e-3 -0.69049-0.14382-1.4219-0.33476-2.042-0.62601-2.033-2.5892-3.4362-4.8345-3.4369z" color="#000000" color-rendering="auto" image-rendering="auto" style="font-feature-settings:normal;font-variant-alternates:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-position:normal;isolation:auto;mix-blend-mode:normal;shape-padding:0;text-decoration-color:#000000;text-decoration-line:none;text-decoration-style:solid;text-indent:0;text-orientation:mixed;text-transform:none;white-space:normal"> </path> <path d="m281.67 229.68c-6.5492 6.4699-10.616 15.447-10.616 25.347 0 7.0626 2.0718 13.653 5.6379 19.198l0.86758 1.2693c0.8646 1.2649 2.0641 2.1192 3.5457 2.1201 2.2281 1e-3 4.0346-1.8058 4.0339-4.0338-3.7e-4 -1.0655-0.50216-2.016-1.1744-2.8427-0.5747-0.70663-1.0534-1.5768-1.512-2.4103-2.1674-3.9394-3.4006-8.4678-3.4006-13.301 0-7.7048 3.1245-14.644 8.1787-19.64z" color="#000000" color-rendering="auto" image-rendering="auto" style="font-feature-settings:normal;font-variant-alternates:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-position:normal;isolation:auto;mix-blend-mode:normal;shape-padding:0;text-decoration-color:#000000;text-decoration-line:none;text-decoration-style:solid;text-indent:0;text-orientation:mixed;text-transform:none;white-space:normal"> </path> </g> <g fill="#071b40" fill-opacity=".29804" fill-rule="evenodd"> <g stroke-width="1.3525"> <path d="m291.86 206.48a5.1041 5.1041 0 0 1 -5.1041 5.1041 5.1041 5.1041 0 0 1 -5.1041 -5.1041 5.1041 5.1041 0 0 1 5.1041 -5.1041 5.1041 5.1041 0 0 1 5.1041 5.1041z"> </path> <path d="m274.75 217.8a5.1041 5.1041 0 0 1 -5.1041 5.1041 5.1041 5.1041 0 0 1 -5.1041 -5.1041 5.1041 5.1041 0 0 1 5.1041 -5.1041 5.1041 5.1041 0 0 1 5.1041 5.1041z"> </path> <path d="m263.36 234.81a5.1041 5.1041 0 0 1 -5.1041 5.1041 5.1041 5.1041 0 0 1 -5.1041 -5.1041 5.1041 5.1041 0 0 1 5.1041 -5.1041 5.1041 5.1041 0 0 1 5.1041 5.1041z"> </path> </g> <g stroke-width="1.0687"> <path d="m320.64 285.07a4.0328 4.0328 0 0 1 -4.0328 4.0328 4.0328 4.0328 0 0 1 -4.0328 -4.0328 4.0328 4.0328 0 0 1 4.0328 -4.0328 4.0328 4.0328 0 0 1 4.0328 4.0328z"> </path> <path d="m301.02 285.09a4.0328 4.0328 0 0 1 -4.0328 4.0328 4.0328 4.0328 0 0 1 -4.0328 -4.0328 4.0328 4.0328 0 0 1 4.0328 -4.0328 4.0328 4.0328 0 0 1 4.0328 4.0328z"> </path> <path d="m336.5 273.53a4.0328 4.0328 0 0 1 -4.0328 4.0328 4.0328 4.0328 0 0 1 -4.0328 -4.0328 4.0328 4.0328 0 0 1 4.0328 -4.0328 4.0328 4.0328 0 0 1 4.0328 4.0328z"> </path> </g> <g stroke-width="1.5897"> <path d="m312.8 180.37a5.9989 5.9989 0 0 1 -5.9989 5.9989 5.9989 5.9989 0 0 1 -5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 5.9989z"> </path> <path d="m332.03 182.94a5.9989 5.9989 0 0 1 -5.9989 5.9989 5.9989 5.9989 0 0 1 -5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 5.9989z"> </path> <path d="m350.06 190.37a5.9989 5.9989 0 0 1 -5.9989 5.9989 5.9989 5.9989 0 0 1 -5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 5.9989z"> </path> <path d="m365.49 202.19a5.9989 5.9989 0 0 1 -5.9989 5.9989 5.9989 5.9989 0 0 1 -5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 5.9989z"> </path> <path d="m377.25 217.59a5.9989 5.9989 0 0 1 -5.9989 5.9989 5.9989 5.9989 0 0 1 -5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 5.9989z"> </path> <path d="m384.78 235.81a5.9989 5.9989 0 0 1 -5.9989 5.9989 5.9989 5.9989 0 0 1 -5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 -5.9989 5.9989 5.9989 0 0 1 5.9989 5.9989z"> </path> </g> </g> <g fill-rule="evenodd" shape-rendering="auto"> <path d="m295.46 175.21c-39.056 5.5116-69.203 39.138-69.203 79.69h11.979c0-34.643 25.557-63.171 58.89-67.839z" color="#000000" color-rendering="auto" fill="url(#linearGradient20775)" image-rendering="auto" style="font-feature-settings:normal;font-variant-alternates:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-position:normal;isolation:auto;mix-blend-mode:normal;shape-padding:0;text-decoration-color:#000000;text-decoration-line:none;text-decoration-style:solid;text-indent:0;text-orientation:mixed;text-transform:none;white-space:normal"> </path> <path d="m354.02 255.05c0 26.184-21.117 47.302-47.302 47.302-22.44 0-41.114-15.509-46.034-36.426l-10.01 2.4168c6.0075 25.359 28.875 44.292 56.044 44.292 31.742 0 57.584-25.842 57.584-57.584z" color="#000000" color-rendering="auto" fill="url(#linearGradient20795)" image-rendering="auto" style="font-feature-settings:normal;font-variant-alternates:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-position:normal;isolation:auto;mix-blend-mode:normal;shape-padding:0;text-decoration-color:#000000;text-decoration-line:none;text-decoration-style:solid;text-indent:0;text-orientation:mixed;text-transform:none;white-space:normal"> </path> <path d="m306.7 219.37c-10.191 0-19.404 4.3099-25.911 11.201l5.893 5.3366c5.0292-5.267 12.128-8.5393 20.018-8.5393 15.319 0 27.651 12.335 27.651 27.654 0 3.852-0.78457 7.5121-2.1955 10.838l7.3396 3.116c1.8342-4.2892 2.8538-9.0054 2.8538-13.954 0-19.642-16.007-35.652-35.649-35.652z" color="#000000" color-rendering="auto" fill="url(#linearGradient20785)" image-rendering="auto" style="font-feature-settings:normal;font-variant-alternates:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-position:normal;isolation:auto;mix-blend-mode:normal;shape-padding:0;text-decoration-color:#000000;text-decoration-line:none;text-decoration-style:solid;text-indent:0;text-orientation:mixed;text-transform:none;white-space:normal"> </path> </g> </g> </svg> <div> Industry Dive is an Informa business </div> </div> <div class="baseline-footer"> © 2024 <a href="http://www.industrydive.com">Industry Dive</a>. All rights reserved. | View our <a href="http://www.industrydive.com/industries/">other publications</a> | <a href="http://www.industrydive.com/privacy-policy/">Privacy policy</a> | <a href="http://www.industrydive.com/terms-of-use/">Terms of use</a> | <a href="http://www.industrydive.com/takedown-policy/">Take down policy</a>. <br> <a href="#" onclick="Osano.cm.showDrawer('osano-cm-dom-info-dialog-open')">Cookie Preferences / Do Not Sell</a> </div> </div> </div> </div>  <nav class="mobile-menu"> <div class="mm-top-bar"> <button class="mobile-menu-toggle"> <img src="/static/img/menu_icons/close.svg?273117231121" width="20" height="20" alt="close menu"/> </button> <div class="mm-search"> <form action="/search/" method="GET" data-ajax="false"> <label for="search-mobile"> <span class="screen-reader-text">Search</span> <input id="search-mobile" type="search" name="q" placeholder="Search" data-role="none"> </label> <button type="submit" value="" data-role="none" class="search-button-front analytics t-search-navigation-mobile"> <img src="/static/img/menu_icons/search.svg?320116291121" width="15" height="15" alt="search"> </button> </form> </div> </div> <ul class="mm-list list-no-bullets"> <li> <a href="/" class="analytics t-dash-navigation-mobile"> <span>Home</span> </a> </li> <li class="mm-accordion"> <button> <span>Voices</span> <span class="accordion-toggle-arrow"> <img src="/static/img/menu_icons/chevron_down.svg?102717100918" width="16" height="9" alt="down arrow" loading="lazy"> </span> </button> <ul class="list-no-bullets"> <li> <a class="analytics t-voices-navigation-qa" href="/q-and-a">Q&A</a> </li> <li> <a class="analytics t-voices-navigation-profiles" href="/profiles">Profiles</a> </li> <li> <a class="analytics t-voices-navigation-biotechspotlight" href="/topic/biotech-spotlight/">Biotech Spotlight</a> </li> <li> <a class="analytics t-voices-navigation-first90days" href="/topic/first-90-days/">First 90 Days</a> </li> <li> <a class="analytics t-voices-navigation-opinions" href="/opinion">Opinions</a> </li> </ul> </li> <li class="mm-accordion"> <button> <span>Topics</span> <span class="accordion-toggle-arrow"> <img src="/static/img/menu_icons/chevron_down.svg?102717100918" width="16" height="9" alt="down arrow" loading="lazy"> </span> </button> <ul class="list-no-bullets"> <li> <a class="analytics t-topic-navigation-mobile-biotech" href="/topic/biotech/">Biotech</a> </li> <li> <a class="analytics t-topic-navigation-mobile-commercialization" href="/topic/commercialization/">Commercialization</a> </li> <li> <a class="analytics t-topic-navigation-mobile-leadership" href="/topic/leadership/">Leadership</a> </li> <li> <a class="analytics t-topic-navigation-mobile-manufacturing" href="/topic/manufacturing/">Manufacturing</a> </li> <li> <a class="analytics t-topic-navigation-mobile-patient" href="/topic/patient/">Patient</a> </li> <li> <a class="analytics t-topic-navigation-mobile-pharma" href="/topic/pharma/">Pharma</a> </li> <li> <a class="analytics t-topic-navigation-mobile-policy-regulation" href="/topic/policy-regulation/">Policy & Regulation</a> </li> <li> <a class="analytics t-topic-navigation-mobile-research-development" href="/topic/research-development/">Research & Development</a> </li> </ul> </li> <li> <a href="/library/" class="analytics t-library-navigation-mobile">Library</a> </li> <li> <a href="/events/" class="analytics t-events-navigation-mobile">Events</a> </li> <li> <a href="/press-release/" class="analytics t-press-releases-navigation-mobile">Press Releases</a> </li> <li class="mm-accordion"> <button> <span>PharmaVoice 100</span> <span class="accordion-toggle-arrow"> <img src="/static/img/menu_icons/chevron_down.svg?102717100918" width="16" height="9" alt="down arrow" loading="lazy"> </span> </button> <ul class="list-no-bullets"> <li> <a href="https://www.pharmavoice.com/news/pharmavoice-100-nomination-form/611747/" class="analytics t-pv100-navigation-nominate"> Nominate </a> </li> <li> <a href="/news/pv100-pharma-leaders-executives/726233/" class="analytics t-pv100-navigation-current100"> 2024 PV100 </a> </li> <li> <a href="/news/pharmavoice100-pv100-pharma-leaders/690951/" class="analytics t-pv100-navigation-past"> 2023 PV100 </a> </li> </ul> </li> </ul> <section class="signup mm-signup"> <div class="row"> <div class="large-9 medium-10 medium-centered columns"> <h3 class="display-heading-03 display-heading-03--loud">Get PharmaVoice in your inbox</h3> <p class="subhead">The free newsletter covering the top industry headlines</p> <form class="form js-form-email-validate" name="signup" action="/signup/" method="POST"> <label for="id_824bcd_email" class="email-input js-email-input"> <span class="screen-reader-text">Email:</span> <input type="email" name="email" placeholder="Work email address" class="email" required id="id_824bcd_email"> </label> <input type="hidden" name="signup_box_location" value="integrated_menu"> <input type="hidden" name="signup_initial_url_path" value="/news/merck-keytruda-cancer-oncology-subcutaneous-roche-bristol-myers/733544/"> <input type="hidden" name="js_enabled" value="0" id="id_824bcd_js_enabled"> <ul class="signup-list list-no-bullets"> <li> <label><span class="screen-reader-text">Select user consent:</span></label> <input type="checkbox" name="user_consent" id="id_user_consent-integrated_menu" value="1" class="checkbox"/> <label for="id_user_consent-integrated_menu"> <span class="signup-user-consent_box"> <span> By signing up to receive our newsletter, you agree to our <a href="https://www.industrydive.com/terms-of-use/" target="_blank">Terms of Use</a> and <a href="https://www.industrydive.com/privacy-policy/" target="_blank">Privacy Policy</a>. You can unsubscribe at anytime. </span> </span> </label> </li> </ul> <button class="button button--medium signup-button" type="submit" value="Sign up">Sign up</button> <script type="module" src="/static/js/dist/sendEmailToLytics.bundle.js?520216211124" ></script> <label class="error email_error" style="display:none;">A valid email address is required.</label> <label class="error newsletter-error" style="display:none;">Please select at least one newsletter.</label> </form> </div> </div> </section> </nav> <script src="/static/js/news.js?543416080722" async></script> <script> //Add styling for pdf only if admin button is clicked $(".download-promoted-story-button").click(function(){ $("body").addClass("admin-pdf-styling"); }); $(".js-social-button-print, .js-social-icon-print").click(function(){ if ($("body").hasClass("admin-pdf-styling")){ $("body").removeClass("admin-pdf-styling"); } }); </script> <script type="application/ld+json"> { "@context": "https://schema.org", "@type": "NewsArticle", "headline": "Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals", "image": [ "https://www.pharmavoice.comhttps://imgproxy.divecdn.com/a9ZMdtDzjeP58c9eV5G1RgoGKvjyMyGVEBHygJ6CpjA/g:ce/rs:fill:1200:1200:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp", "https://www.pharmavoice.comhttps://imgproxy.divecdn.com/goEMUJaZIntiHLh5UWdRDs2ZCf5s7qglSQ0hzAEACys/g:ce/rs:fill:1200:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp", "https://www.pharmavoice.comhttps://imgproxy.divecdn.com/A7pON6IqKty5yYlpZ78CA3C2CWfmw2WShAtwv0IbNeg/g:ce/rs:fill:1200:675:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9rZXl0cnVkYS5wbmc=.webp" ], "datePublished": "2024-11-21T07:12:57", "dateModified": "", "author": [ { "@type": "Person", "name": "Michael Gibney", "url": "www.pharmavoice.com/editors/mgibney/" } ] } </script> <script type="module" src="/static/js/dist/article.bundle.js?520216211124" ></script>  <script type="module" src="/static/js/dist/signupValidation.bundle.js?520216211124" ></script> <script type="module" src="/static/js/dist/gtmEvents.bundle.js?520216211124" ></script>  <script type="module" src="/static/js/dist/smartQuotes.bundle.js?520216211124" ></script> <script> // Set cookie if we're on mobile app. Expire if we're not. This affects // which template is used to display the site to the user. $(document).ready(function() { // Get integer value of mobileapp param from URL and default to 0 if it doesn't exist var mobileapp = ''; // Set cookie if mobileapp is 1 or 2 or expire cookie if mobileapp == 0 if (mobileapp == '0') { document.cookie = 'mobileapp=; path=/; expires=Thu, 01 Jan 1970 00:00:01 GMT;'; } else if (mobileapp == '1' || mobileapp == '2') { document.cookie = 'mobileapp=' + mobileapp + '; path=/;'; } // There's no need to immediately load or preload print.css since it's not needed on page // load. Therefore, load it when the document is ready var stylesheet=document.createElement("link"); stylesheet.setAttribute("rel", "stylesheet"); stylesheet.setAttribute("type", "text/css"); stylesheet.setAttribute("media", "print"); if (window.location.pathname.includes('trendline')) { stylesheet.setAttribute("href", "/static/css/print_trendline.css?300116211124"); } else { stylesheet.setAttribute("href", "/static/css/print.css?300116211124"); } document.getElementsByTagName("head")[0].appendChild(stylesheet); }); </script>   <script src="https://ak.sail-horizon.com/spm/spm.v1.min.js"></script> <script type="text/javascript"> $(function() { // Sailthru Personalization Engine Setup var sailthru_setup = { customerId: '12ab35a80530ffa5450add9c09f5de04', domain: 'horizon.pharmavoice.com', spider: true }; if (window.Sailthru) { Sailthru.init(sailthru_setup); } }); </script> </body> </html>

CINXE.COM

Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals | PharmaVoice