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Manuals and step-by-step examples for Prism 5 - FAQ 1759 - GraphPad
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text--bold-normal"><span>KNOWLEDGEBASE</span> - <span>ARTICLE #1759</span></div> <h1 class="heading-xl mt-2 mb-4">Manuals and step-by-step examples for Prism 5</h1> <span style="text-transform:none;"></span> </div> </div> </div> </section> <section class="section pt-2"> <div class="grid-container"> <div class="grid-x align-center"> <div class="cell medium-11 large-9"> <div class="section__wysiwyg"> <p> Note that Prism 5 is several years old. If you use Prism 5, make sure you are <a href="http://www.graphpad.com/support/prism-5-updates/">up to date</a>.</p> <p> <strong>Manuals</strong></p> <p style="margin-left: 40px;"> <a href="http://www.graphpad.com/downloads/docs/Prism5Stats.pdf">Download the Prism 5 Statistics Help Guide (2.3MB pdf)</a></p> <p style="margin-left: 40px;"> <a href="http://www.graphpad.com/downloads/docs/Prism5Regression.pdf">Download the Prism 5 Regression Guide (2.9MB pdf)</a></p> <p style="margin-left: 40px;"> <a href="http://www.graphpad.com/help/prism5/prism5help.html">Access the Prism 5 Manual online</a></p> <p> <strong>Getting Started</strong></p> <p style="margin-left: 40px;"> <a href="http://www.graphpad.com/help/Prism5/Prism5Help.html?using_tour_overview.htm" target="_blank">Take a tour of Prism</a></p> <p> <strong>Step-by-Step Examples - Nonlinear Regression</strong></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_example_enzyme_kinetics.htm" target="_blank">Fitting an enzyme kinetics curve</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_example_comparing_two_enzyme_k.htm" target="_blank">Comparing two enzyme kinetics models</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_example_ria.htm" target="_blank">Interpolating from a sigmoidal standard curve</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_example_outlier_detection.htm" target="_blank">Automatic outlier elimination</a> (exponential decay)</p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_example_global_nonlin.htm" target="_blank">Global nonlinear regression</a> (two dose-response curves)</p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_example_ambiguous_fit.htm" target="_blank">Dependency and ambiguous fits</a> (dose-response curves)</p> <p class="p_Heading2"> <strong><span class="f_Heading2">Detailed help to fit built-in equations</span></strong></p> <p class="p_BodyText"> <span class="f_BodyText">Prism comes with dozens of built-in equations to use in nonlinear regression (of course you can also add your own equations). For each of the built-in equations, we provide a detailed description with step-by-step instructions. Here are a few examples:</span></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_dr_stim_variable.htm" target="_blank">Equation: log(agonist) vs. response -- Variable slope</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_dr_inhibit_normalized.htm" target="_blank">Equation: log(inhibitor) vs. normalized response</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_exponential_decay_1phase.htm" target="_blank">Equation: One phase exponential decay</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_one_site_competition_ki.htm" target="_blank">Equation: Competitive binding - One site - Fit Ki</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_dissociation.htm" target="_blank">Equation: Receptor binding - Dissociation kinetics</a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_mixered_model.htm" target="_blank">Equation: Mixed-model enzyme inhibition </a></p> <p style="margin-left: 40px;"> <a href="/guides/prism/5/user-guide/prism5help.html?reg_gaddumschild.htm" target="_blank">Equation: Gaddum/Schild EC50 shift</a></p> <p> <strong>Step-by-Step Statistical Examples</strong></p> <p style="margin-left: 40px;"> Descriptive Statistics</p> <p style="margin-left: 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_columnstatistics.htm" target="_blank">Column statistics</a></p> <p style="margin-left: 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_frequency_distribution.htm" target="_blank">Frequency distribution</a></p> <p class="p_Heading3" style="margin-left: 40px;"> <span class="f_Heading3">Compare two groups</span></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_ttestunpaired.htm" target="_blank">Unpaired t test from raw data</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_how_to_unpaired5_average.htm" target="_blank">Unpaired t test from averaged data</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_how_to_ttest_paired.htm" target="_blank">Paired t test </a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_how_to_do_an_unpaired_t_test_w_3.htm" target="_blank">Mann-Whitney test</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_how_to_do_an_unpaired_t_test_w_3_2.htm" target="_blank">Wilcoxon matched pairs test</a></p> <p class="p_Heading3" style="margin-left: 40px;"> <span class="f_Heading3">Compare three or more groups </span></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_1wayanova.htm" target="_blank">One-way ANOVA</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stats_howto_onewayanova_rm.htm" target="_blank">Repeated measures one-way ANOVA</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_how_to_kruskal_wallis_test.htm" target="_blank">Kruskal-Wallis test</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_how_to_friedman_test.htm" target="_blank">Friedman test</a></p> <p class="p_Heading3" style="margin-left: 40px;"> <span class="f_Heading3">Two-way ANOVA</span></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_2wayanova.htm" target="_blank">Two-way ANOVA</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?how_to_rm_2way_anova.htm" target="_blank">Two-way ANOVA. Repeated measures by row</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?how_to_rm_2way_anova_3.htm" target="_blank">Two-way ANOVA. Repeated measures by column</a></p> <p class="p_Heading3" style="margin-left: 40px;"> <span class="f_Heading3">Categorical outcomes</span></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_contingency_tables.htm" target="_blank">Contingency table analysis</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_survival.htm" target="_blank">Survival analysis</a></p> <p class="p_Heading3" style="margin-left: 40px;"> <span class="f_Heading3">Diagnostic lab tests</span></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_howto_roc.htm" target="_blank">ROC curve</a></p> <p style="margin: 0px 0px 10px 80px;"> <a href="/guides/prism/5/user-guide/prism5help.html?stat_bland_altman.htm" target="_blank">Bland-Altman plot</a></p> </div> </div> </div> </div> </section> </article> <section class="section gp-light-gray-3"> <div class="grid-container"> <div class="grid-x"> <div class="cell"> <h2 class="heading heading-xl text-center mb-4"> Explore the Knowledgebase </h2> </div> </div> <div class="grid-x align-center mb-12"> <div class="cell medium-9 text-center"> <form class="search-form field" method="get" action="/search" id="faqsearch"> <input name="index" type="hidden" value="520255"> <input id="searchquery" name="searchquery" type="search" class="field__input field__search br-0 h-12 pr-14" placeholder="Search..." autocomplete="off"> <button type="submit" class="search-form__btn br-0 h-12"> <span class="gp-icon gp-icon-search"></span> </button> </form><!-- end search-form --> </div> </div> </div> </section> <section class="section gp-purple-gradient"> <div class="grid-container"> <div class="grid-x align-center"> <div class="cell text-center"> <p class="text-xl text--inverted">Analyze, graph and present your scientific work easily with GraphPad Prism. 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