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Research topics covered include cancer treatment and metastasis mechanisms, tumor microenvironment, breast cancer, lymphomas, hematologic malignancies, thyroid cancer, lung cancer, gastric cancer, esophageal cancer, brain tumors, melanomas, bile duct cancer, nasopharyngeal cancer, cervical cancer, cancer stem cells, oncolytic viruses, and early diagnosis, treatment, and post-metastasis therapeutic strategies for these cancers."><meta data-n-head="ssr" name="keywords" content=""><meta data-n-head="ssr" name="twitter:title" content="Journal of Cancer Metastasis and Treatment - OAE Publishing Inc."><meta data-n-head="ssr" name="twitter:type" content="OAE Publishing Inc."><meta data-n-head="ssr" name="twitter:description" content="The Journal of Cancer Metastasis and Treatment, under the leadership of Executive Chief Editor Ciro Isidoro, is dedicated to the latest research on the etiology, mechanisms, and treatment of various cancers with a focus on metastasis. Research topics covered include cancer treatment and metastasis mechanisms, tumor microenvironment, breast cancer, lymphomas, hematologic malignancies, thyroid cancer, lung cancer, gastric cancer, esophageal cancer, brain tumors, melanomas, bile duct cancer, nasopharyngeal cancer, cervical cancer, cancer stem cells, oncolytic viruses, and early diagnosis, treatment, and post-metastasis therapeutic strategies for these cancers."><meta data-n-head="ssr" property="og:url" content="/jcmt"><meta data-n-head="ssr" property="og:type" content="OAE Publishing Inc."><meta data-n-head="ssr" property="og:site_name" content="Journal of Cancer Metastasis and Treatment"><meta data-n-head="ssr" property="og:title" content="Journal of Cancer Metastasis and Treatment"><title>Journal of Cancer Metastasis and Treatment - OAE Publishing Inc.</title><link data-n-head="ssr" rel="icon" type="image/x-icon" href="/favicon.ico"><link data-n-head="ssr" rel="canonical" 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style="padding-left:10px;padding-right:10px;" data-v-2c8370e1><div data-v-c1f41ab4 data-v-2c8370e1><div class="banner_box" data-v-c1f41ab4><div class="grid-content banner_cont pad_r_10" data-v-c1f41ab4><div class="banner_box_b" data-v-c1f41ab4> <div class="swiper-container" data-v-5c8e3c6d data-v-c1f41ab4><div class="swiper-wrapper" data-v-5c8e3c6d><div class="swiper-slide" data-v-5c8e3c6d><a href="https://www.oaepublish.com/jcmt/anniversary" data-v-5c8e3c6d><div class="tit" data-v-5c8e3c6d><div class="title" data-v-5c8e3c6d><a href="https://www.oaepublish.com/jcmt/anniversary" data-v-5c8e3c6d><span data-v-5c8e3c6d>10th Anniversary of <i>Journal of Cancer Metastasis and Treatment</i> </span></a></div> <div class="title_sm" data-v-5c8e3c6d><span data-v-5c8e3c6d>To celebrate this milestone, we have organized a series of special content and events to commemorate <i>JCMT</i>'s decade of advancing cancer research.</span></div></div> <img src="https://i.oaes.cc/uploads/20241113/9ee8de45dd8c4d4f82d2b96bd5f0b7ec.jpg" alt data-v-5c8e3c6d></a></div><div class="swiper-slide" data-v-5c8e3c6d><a href="https://www.oaepublish.com/news/jcmt.888" data-v-5c8e3c6d><div class="tit" data-v-5c8e3c6d><div class="title" data-v-5c8e3c6d><a href="https://www.oaepublish.com/news/jcmt.888" data-v-5c8e3c6d><span data-v-5c8e3c6d>Celebrating 35 Editorial Board Members of <i>Journal of Cancer Metastasis and Treatment</i> Journal Named Among the “World’s Top 2% Scientists 2024”</span></a></div> <div class="title_sm" data-v-5c8e3c6d><span data-v-5c8e3c6d>On September 16, 2024, a team led by Professor John P.A. Ioannidis from Stanford University, in collaboration with Elsevier, published the seventh edition of the World's Top 2% Scientists list for 2024.</span></div></div> <img src="https://i.oaes.cc/uploads/20241113/5687e10af29b4d90b94f231a647c01fb.jpg" alt data-v-5c8e3c6d></a></div><div class="swiper-slide" data-v-5c8e3c6d><a href="https://www.oaepublish.com/specials/jcmt.2175" data-v-5c8e3c6d><div class="tit" data-v-5c8e3c6d><div class="title" data-v-5c8e3c6d><a href="https://www.oaepublish.com/specials/jcmt.2175" data-v-5c8e3c6d><span data-v-5c8e3c6d>Selected Papers from 2nd International Cancer Science Congress (ICSC) 2024 </span></a></div> <div class="title_sm" data-v-5c8e3c6d><span data-v-5c8e3c6d>We welcome interested scholars to participate in this conference and submit your valuable manuscripts. </span></div></div> <img src="https://i.oaes.cc/uploads/20240905/1c8db532e8a14e0cafa135e88ff0a009.jpg" alt data-v-5c8e3c6d></a></div><div class="swiper-slide" data-v-5c8e3c6d><a href="https://www.oaepublish.com/webinars/jcmt.286" data-v-5c8e3c6d><div class="tit" data-v-5c8e3c6d><div class="title" data-v-5c8e3c6d><a href="https://www.oaepublish.com/webinars/jcmt.286" data-v-5c8e3c6d><span data-v-5c8e3c6d>International Webinar for "Gastrointestinal Stroma-Tumor (GIST)" </span></a></div> <div class="title_sm" data-v-5c8e3c6d><span data-v-5c8e3c6d>Welcome to this international webinar organized by Prof. Giuliano Ramadori, scheduled for September 23, 2024. </span></div></div> <img src="https://i.oaes.cc/uploads/20240808/0f34bede744847798428c75d80b79ad4.png" alt data-v-5c8e3c6d></a></div><div class="swiper-slide" data-v-5c8e3c6d><a href="https://www.oaepublish.com/specials/jcmt.1718" data-v-5c8e3c6d><div class="tit" data-v-5c8e3c6d><div class="title" data-v-5c8e3c6d><a href="https://www.oaepublish.com/specials/jcmt.1718" data-v-5c8e3c6d><span data-v-5c8e3c6d>Special Issue: Recent Developments in the Surgical Management of Hepatocellular Carcinoma</span></a></div> <div class="title_sm" data-v-5c8e3c6d><span data-v-5c8e3c6d>We welcome all high-quality papers submitted to this special issue! 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data-v-2c8370e1>Cancer Drug Resistance</h4> <div class="jour_edit" data-v-2c8370e1>Editor-in-Chief: Godefridus J. 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Antonio Giordano",journal_id:j,volume:F,year:Z,section_id:m,special_name:a,url_doi:"2394-4722.2024.63",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002Fa3977867-04b2-4394-9124-abaa22312794\u002Fjcmt4063.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Aldo d’Alessandro'\u003E Aldo d’Alessandro, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Anca Florentina Deaconu'\u003E Anca Florentina Deaconu, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Sandro Mandolesi'\u003E Sandro Mandolesi, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Federico Pio Fabrizio'\u003E Federico Pio Fabrizio\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-9122-1348' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Federico Pio Fabrizio'\u003E\u003C\u002Fa\u003E, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Massimo Lombardi'\u003E Massimo Lombardi, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Giovanna Liguori'\u003E Giovanna Liguori, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Giovanni Pepe'\u003E Giovanni Pepe, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Nicola Marino'\u003E Nicola Marino, ... \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Antonio Giordano'\u003E Antonio Giordano",journal_path:d,video_img:a,image_list:cl,abstract:"\u003Cp\u003EThe molecular classification of breast cancer plays a pivotal role in developing personalized treatment strategies, with the aim of improving therapeutic outcomes. Despite significant advancements, current diagnostic workflows are hindered by several challenges, including pre-analytical variability, interpretive ambiguity, and inconsistencies in threshold definitions, particularly in cases involving human epidermal growth factor receptor 2 (HER2)-low breast cancer. In this context, liquid biopsy technologies have emerged as promising tools for refining breast cancer diagnostics. Techniques such as circulating tumor DNA and circulating tumor cell analysis provide a non-invasive approach to assessing tumor-associated biomarkers. These methodologies are particularly advantageous for analyzing low-abundance materials, such as formalin-fixed paraffin-embedded samples and liquid biopsies, thus enhancing the precision of molecular classification and informing more targeted therapeutic decisions for breast cancer patients. This review aims to explore the potential of liquid biopsy in addressing the limitations of current diagnostic practices, with a specific focus on its application in HER2-low breast cancer. Furthermore, it advocates for a transition toward high-throughput RNA-based screening and quantification, which may address critical unmet clinical needs.\u003C\u002Fp\u003E"},{article_id:"7230",title:"Interconnections within the tumor microenvironment: extracellular vesicles as critical players of metabolic reprogramming in tumor cells",image:cm,tag:bt,doi:"10.20517\u002F2394-4722.2024.78",date_published:"1727625600",section:r,authors:"Carol Costa Encarnação, ... Mariana Renovato-Martins\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0003-4687-1381' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Mariana Renovato-Martins'\u003E\u003C\u002Fa\u003E",journal_id:j,volume:F,year:Z,section_id:m,special_name:a,url_doi:"2394-4722.2024.78",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002Fafa220a7-79b5-4ced-9cf2-1f492c138c90\u002Fjcmt10078.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Carol Costa Encarnação'\u003E Carol Costa Encarnação, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Giselle Marianne Faria'\u003E Giselle Marianne Faria, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Victor Aguiar Franco'\u003E Victor Aguiar Franco, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Luiz Gabriel Xavier Botelho'\u003E Luiz Gabriel Xavier Botelho, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='João Alfredo Moraes'\u003E João Alfredo Moraes\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-8563-6432' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='João Alfredo Moraes'\u003E\u003C\u002Fa\u003E, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Mariana Renovato-Martins'\u003E Mariana Renovato-Martins\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0003-4687-1381' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Mariana Renovato-Martins'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:a,image_list:cm,abstract:"\u003Cp\u003EMetabolic reprogramming is an intrinsic characteristic of cancer, contributing to its establishment and progression, survival, high proliferation rates, and increased migratory and invasive potential; tumor cells establish an intimate relationship with the surrounding microenvironment, where sustained communication allows the stromal fraction of the tumor microenvironment (TME) to supply energetic substrates and facilitate the biosynthesis of macromolecules, thereby promoting tumor progression. In this context, extracellular vesicles (EVs) emerge as potential communication vehicles, carrying inside content reflecting the cellular environment of origin and thus modulating the phenotype of recipient cells. The potential of EVs as modulators in the TME has been highlighted and is now consensual; however, most available articles have focused on revealing the effect of EVs in modulating tumor phenotypes and signaling pathways in tumor cells. Regarding the metabolic modulation sustained by EVs, studies have demonstrated the role of cancer cells’ EVs as modulators of surrounding cells, like immune cells, fibroblasts, and adipocytes. Therefore, this review aims to: \u003Ci\u003Ei.\u003C\u002Fi\u003E highlight the most recent studies evaluating the role of cellular vesicles released by those cells within the microenvironment in the metabolic reprogramming of cancer cells; \u003Ci\u003Eii.\u003C\u002Fi\u003E compile scientific evidence proposing how EVs could modulate the metabolic profile of tumor stem cells and lymphocytes, particularly given the lack of studies focused on such approaches; and \u003Ci\u003Eiii.\u003C\u002Fi\u003E highlight possible effects of vesicles, as the metabolic modulation induced by these vesicles could have anticancer potential.\u003C\u002Fp\u003E"},{article_id:"7214",title:"The role of miRNAs in the extracellular vesicle-mediated interplay between breast tumor cells and cancer-associated fibroblasts",image:cn,tag:"27",doi:"10.20517\u002F2394-4722.2024.76",date_published:"1727366400",section:r,authors:"Chen Li, ... Qifeng Yang\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0003-0576-8513' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Qifeng Yang'\u003E\u003C\u002Fa\u003E",journal_id:j,volume:F,year:Z,section_id:m,special_name:a,url_doi:"2394-4722.2024.76",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F27820a4f-7eeb-4057-8aae-97c2894b0758\u002Fjcmt4076.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Chen Li'\u003E Chen Li, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Chao Yang'\u003E Chao Yang, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Qifeng Yang'\u003E Qifeng Yang\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0003-0576-8513' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Qifeng Yang'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:a,image_list:cn,abstract:"\u003Cp\u003EThe tumor microenvironment (TME) of breast cancer (BC) is depicted as an immunosuppressive dwelling that comprises a myriad of cell types embedded in the extracellular matrix. As one of the most abundant cell populations within the TME, cancer-associated fibroblasts (CAFs) play indispensable roles in increasing cancer aggressiveness and promoting resistance to standard-of-care therapies. Extracellular vesicles (EVs) represent a diverse array of biological nanoparticles, encompassing exosomes, microvesicles, and apoptotic bodies. In recent years, these cell-derived membranous structures have raised great interest as they can encapsulate numerous types of cellular cargo, such as proteins, lipids, and miRNAs. By transmitting bioactive content to recipient cells, EVs play pivotal roles in intercellular communication between CAFs and tumor cells. EVs secreted from tumor cells typically activate resident fibroblasts to acquire a myofibroblastic phenotype, while EVs diffused by CAFs, in turn, substantially increase the progression of BC. This review summarizes the latest findings to highlight the functional role of EV cargo, especially miRNAs, in the regulatory network. A better understanding of the EV-mediated cell-cell interactions is crucial to achieving effective treatment in patients with BC.\u003C\u002Fp\u003E"},{article_id:"7143",title:"Renin-angiotensin-system and clear cell renal carcinoma: research advances and future perspectives",image:co,tag:"26",doi:"10.20517\u002F2394-4722.2024.40",date_published:"1725033600",section:r,authors:"Guang Yang\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0001-5271-7079' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Guang Yang'\u003E\u003C\u002Fa\u003E, ... Fei Song\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-8283-6172' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Fei Song'\u003E\u003C\u002Fa\u003E",journal_id:j,volume:F,year:Z,section_id:m,special_name:a,url_doi:"2394-4722.2024.40",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F84b27e36-8a10-4a22-9aa0-921083f19098\u002Fjcmt10040.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Guang Yang'\u003E Guang Yang\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0001-5271-7079' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Guang Yang'\u003E\u003C\u002Fa\u003E, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Yan Wang'\u003E Yan Wang, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Zhi-Wei Lai'\u003E Zhi-Wei Lai, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Hua Zhang'\u003E Hua Zhang, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Yue Zhang'\u003E Yue Zhang, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Fei Song'\u003E Fei Song\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-8283-6172' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Fei Song'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:a,image_list:co,abstract:"\u003Cp\u003EHypertension is a known risk factor for clear cell renal cell carcinoma (ccRCC), yet the underlying mechanisms remain elusive. Studies have confirmed that the renin-angiotensin system (RAS) plays a role beyond regulating blood pressure, influencing various aspects of tumor development and metastasis. Generally, activation of the angiotensin-converting enzyme (ACE)\u002Fangiotensin II (Ang II)\u002Fangiotensin type 1 receptor (AT1R) axis elevates blood pressure and promotes tumor progression, while the activation of the angiotensin-converting enzyme 2 (ACE2)\u002F[Ang-(1-7)]\u002FMas receptor (MasR) axis antagonizes these effects. Consequently, many cardiovascular drugs targeting the RAS may possess both hypotensive and antitumor properties. However, the role of RAS in ccRCC is controversial. To explore this, we reviewed the relevant literature. Surprisingly, apart from ACE2, the activation of RAS may facilitate the progression and metastasis of ccRCC. This unexpected finding suggests caution when using RAS inhibitors in ccRCC patients. This review provides an overview of the RAS, highlights research advances in RAS for ccRCC, elucidates the current status of RAS-targeted drugs in the treatment of ccRCC, and discusses the current challenges and future research directions in this field. In conclusion, the upregulation of other effector peptides and the activation of receptors in the RAS, apart from ACE2, may expedite ccRCC progression. Therefore, careful consideration is needed when using relevant drugs in ccRCC patients with hypertension. This synthesis of available evidence is crucial for informing the clinical management of ccRCC and guiding the development of novel therapeutic strategies.\u003C\u002Fp\u003E"},{article_id:"7101",title:"Surgical approach to hepatocellular carcinoma: a review",image:cp,tag:aN,doi:"10.20517\u002F2394-4722.2024.52",date_published:"1723478400",section:r,authors:"Samantha M. Ruff, Timothy M. Pawlik\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-7994-9870' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Timothy M. Pawlik'\u003E\u003C\u002Fa\u003E",journal_id:j,volume:F,year:Z,section_id:"1718",special_name:"Topic: Recent Developments in the Surgical Management of Hepatocellular Carcinoma",url_doi:"2394-4722.2024.52",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002Fc861a518-8526-4722-a8ef-68961bd73500\u002Fjcmt4052.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Samantha M. Ruff'\u003E Samantha M. Ruff, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Timothy M. Pawlik'\u003E Timothy M. Pawlik\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-7994-9870' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Timothy M. Pawlik'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:a,image_list:cp,abstract:"\u003Cp\u003EHepatocellular carcinoma (HCC) is a primary liver cancer that arises in the setting of chronic liver inflammation and\u002For cirrhosis. Despite advancements in screening and treatment, the incidence and mortality of HCC continue to increase. Treatment for HCC is guided by a patient’s liver function, performance status, and extent of tumor burden. Patients with early-stage HCC are often treated with surgery, liver transplantation, or liver-directed therapy. Unfortunately, many patients have limited surgical options due to advanced-stage disease, recurrent disease after resection, or pre-existing moderate to severe liver dysfunction. These patients are subsequently treated with a combination of atezolizumab and bevacizumab, or durvalumab and tremelimumab. Operative management of HCC requires experienced surgeons and a multidisciplinary team of medical oncologists, radiation oncologists, and hepatologists for appropriate patient selection. Due to the complex management required for these patients, it is critical that the surgical management is informed by updated guidelines and data. We herein review the surgical management and treatment considerations for patients with HCC.\u003C\u002Fp\u003E"}],recent_ids:"7301,7230,7214,7143,7101",view:[{article_id:"1263",title:"Long non-coding RNAs as key regulators of cancer metastasis",image:cq,tag:"1-10",doi:"10.4103\u002F2394-4722.171829",date_published:"1452787200",section:r,authors:"Pratirodh Koirala, ... Yin-Yuan Mo",journal_id:j,volume:l,year:_,section_id:m,special_name:a,url_doi:"2394-4722.171829",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002Faacf921e-f663-4c76-ba32-4ba5f19590d9\u002F1263.pdf",video_url:a,allauthors:"Pratirodh Koirala, De-Hong Zou, Yin-Yuan Mo",journal_path:d,video_img:a,image_list:cq,abstract:"\u003Cp\u003E The recent advances in functional genomics have discovered that a large number of long non-coding RNAs (lncRNAs) are pervasively transcribed from the human genome. Increasing evidence further indicates that lncRNAs are important for gene expression during cell differentiation and development through various mechanisms such as nuclear organization, post-transcription regulation, alternative splicing, and epigenetic regulation. Thus, aberrant expression of lncRNAs can cause abnormality in those cellular functions and lead to various pathological conditions. One of such fatal consequences is cancer metastasis which is responsible for more than 90% of cancer-related deaths. A good understanding of how lncRNAs regulate different genetic and epigenetic changes during different stages of cancer metastasis is important not only for general cancer biology but also for identiﬁ cation of novel biomarkers and therapeutic targets for treatment of metastatic cancer. A signiﬁcant progress has been made regarding the role of lncRNAs in cancer for past several years. In this study, we ﬁrst discuss general functions of lncRNAs and then highlight recent ﬁ ndings of how lncRNAs impact cancer metastasis, and ﬁnally we provide our perspectives on clinical implications of lncRNAs. \u003C\u002Fp\u003E"},{article_id:cr,title:cs,image:aO,tag:ct,doi:cu,date_published:cv,section:r,authors:bu,journal_id:j,volume:o,year:y,section_id:cw,special_name:bv,url_doi:cx,pdf:cy,video_url:a,allauthors:bu,journal_path:d,video_img:a,image_list:aO,abstract:cz},{article_id:cA,title:cB,image:aP,tag:cC,doi:cD,date_published:cE,section:r,authors:bw,journal_id:j,volume:g,year:G,section_id:m,special_name:a,url_doi:cF,pdf:cG,video_url:a,allauthors:bw,journal_path:d,video_img:a,image_list:aP,abstract:cH},{article_id:cI,title:cJ,image:m,tag:cK,doi:cL,date_published:cM,section:r,authors:cN,journal_id:j,volume:s,year:bx,section_id:cO,special_name:by,url_doi:cP,pdf:cQ,video_url:a,allauthors:"Rossana Berardi\u003Ca href='https:\u002F\u002Fwww.researchgate.net\u002Flab\u002FRossana-Berardi-Lab' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Rossana Berardi'\u003E\u003C\u002Fa\u003E, Mariangela Torniai, Edoardo Lenci, Federica Pecci, Francesca Morgese, Silvia Rinaldi",journal_path:d,video_img:a,image_list:m,abstract:cR},{article_id:cS,title:cT,image:aQ,tag:cU,doi:cV,date_published:cW,section:r,authors:bz,journal_id:j,volume:l,year:_,section_id:m,special_name:a,url_doi:cX,pdf:cY,video_url:a,allauthors:bz,journal_path:d,video_img:a,image_list:aQ,abstract:cZ}],view_ids:"1263,2275,1172,3279,1713",download:[{article_id:cr,title:cs,image:aO,tag:ct,doi:cu,date_published:cv,section:r,authors:bu,journal_id:j,volume:o,year:y,section_id:cw,special_name:bv,url_doi:cx,pdf:cy,video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Stanley J. Oiseth'\u003E Stanley J. Oiseth, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Mohamed S. Aziz'\u003E Mohamed S. Aziz",journal_path:d,video_img:a,image_list:aO,abstract:cz},{article_id:"3026",title:"Photodynamic therapy in cancer treatment - an update review",image:c_,tag:aN,doi:"10.20517\u002F2394-4722.2018.83",date_published:"1553788800",section:r,authors:"Ancély Ferreira dos Santos, ... Leticia Labriola\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0003-3899-6088' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Leticia Labriola'\u003E\u003C\u002Fa\u003E",journal_id:j,volume:s,year:bx,section_id:"217",special_name:c$,url_doi:"2394-4722.2018.83",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F795916d5-fa0f-4f76-99c1-1397d98796c4\u002F3026.pdf",video_url:"https:\u002F\u002Fv1.oaepublish.com\u002Ffiles\u002Ftalkvideo\u002F3026.mp4",allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Ancély Ferreira dos Santos'\u003E Ancély Ferreira dos Santos, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Daria Raquel Queiroz de Almeida'\u003E Daria Raquel Queiroz de Almeida, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Leticia Ferreira Terra'\u003E Leticia Ferreira Terra, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Maurício S. Baptista'\u003E Maurício S. Baptista\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0001-7079-7666' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Maurício S. Baptista'\u003E\u003C\u002Fa\u003E, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Leticia Labriola'\u003E Leticia Labriola\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0003-3899-6088' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Leticia Labriola'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240204\u002F4dbb234c0b834091b32bd2d379f67cc7.jpg",image_list:c_,abstract:"\u003Cp\u003ECancer remains a worldwide health problem, being the disease with the highest impact on global health. Even with all the recent technological improvements, recurrence and metastasis still are the main cause of death. Since photodynamic therapy (PDT) does not compromise other treatment options and presents reduced long-term morbidity when compared with chemotherapy or radiotherapy, it appears as a promising alternative treatment for controlling malignant diseases. In this review, we set out to perform a broad up-date on PDT in cancer research and treatment, discussing how this approach has been applied and what it could add to breast cancer therapy. We covered topics going from the photochemical mechanisms involved, the different cell death mechanisms being triggered by a myriad of photosensitizers up to the more recent-on-going clinical trials.\u003C\u002Fp\u003E"},{article_id:cA,title:cB,image:aP,tag:cC,doi:cD,date_published:cE,section:r,authors:bw,journal_id:j,volume:g,year:G,section_id:m,special_name:a,url_doi:cF,pdf:cG,video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Pravin D. Potdar'\u003E Pravin D. Potdar\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0001-5151-6697' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Pravin D. Potdar'\u003E\u003C\u002Fa\u003E, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Navjeet Kaur Lotey'\u003E Navjeet Kaur Lotey",journal_path:d,video_img:a,image_list:aP,abstract:cH},{article_id:cS,title:cT,image:aQ,tag:cU,doi:cV,date_published:cW,section:r,authors:bz,journal_id:j,volume:l,year:_,section_id:m,special_name:a,url_doi:cX,pdf:cY,video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Gao-Feng Xiong'\u003E Gao-Feng Xiong, \u003Cimg src='https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Febdc743d-8ff2-4cc2-815a-1dd073f7bed8\u002F1713.png' class='author_photo' alt='Ren Xu'\u003E Ren Xu\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-3591-9522' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Ren Xu'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:a,image_list:aQ,abstract:cZ},{article_id:cI,title:cJ,image:m,tag:cK,doi:cL,date_published:cM,section:r,authors:cN,journal_id:j,volume:s,year:bx,section_id:cO,special_name:by,url_doi:cP,pdf:cQ,video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Rossana Berardi'\u003E Rossana Berardi\u003Ca href='https:\u002F\u002Fwww.researchgate.net\u002Flab\u002FRossana-Berardi-Lab' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Rossana Berardi'\u003E\u003C\u002Fa\u003E, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Mariangela Torniai'\u003E Mariangela Torniai, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Edoardo Lenci'\u003E Edoardo Lenci, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Federica Pecci'\u003E Federica Pecci, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Francesca Morgese'\u003E Francesca Morgese, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Silvia Rinaldi'\u003E Silvia Rinaldi",journal_path:d,video_img:a,image_list:m,abstract:cR}],download_ids:"2275,3026,1172,1713,3279"},cited:[{article_id:"4837",title:cg,image:da,tag:"18",doi:"10.20517\u002F2394-4722.2022.08",date_published:"1651766400",section:r,authors:"Polyxeni Vafopoulou, Malamati Kourti\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-4176-8425' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Malamati Kourti'\u003E\u003C\u002Fa\u003E",journal_id:j,volume:N,year:w,section_id:m,special_name:a,url_doi:cf,pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F1858ce41-479a-4354-b623-967f60362200\u002F4837.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Polyxeni Vafopoulou'\u003E Polyxeni Vafopoulou, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Malamati Kourti'\u003E Malamati Kourti\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-4176-8425' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Malamati Kourti'\u003E\u003C\u002Fa\u003E",journal_path:d,video_img:a,image_list:da,abstract:"\u003Cp\u003E\r\n Cancer is a group of diseases with significant morbidity and mortality. In cancer cells, where energy requirements are exceptionally high, angiogenesis, which is the sprouting of new blood vessels from pre-existing ones, is an important process for tumour survival and progression. Hence, extensive research in recent years focuses on the discovery of new anticancer drugs that target angiogenesis. Several methodologies have been developed preclinically, including the inhibition of pro-angiogenic factors and their receptors via micromolecular agents or monoclonal antibodies and the inhibition of other compensatory pathways beyond the traditional angiogenic ones. The purpose of the literature review is to present new anticancer drugs that target the process of angiogenesis and have been under preclinical or clinical investigation during the last five years. Many new anticancer drugs targeting angiogenesis are identified in the literature. The results of the \u003Ci\u003Ein vitro\u003C\u002Fi\u003E and \u003Ci\u003Ein vivo\u003C\u002Fi\u003E evaluation of these drugs show that, apart from inhibiting angiogenesis, they also affect cancer cell proliferation and tumour growth. Recent clinical studies show that these drugs increase the overall or disease-free survival of patients, even those with persistent, chemotherapy-resistant and metastatic types of cancer, although treatment-related side effects are not uncommon. Drugs that target the process of angiogenesis are likely to be the future of anticancer therapy, especially in cases where more traditional treatments do not produce the desired results and where combination regimens of anti-angiogenic agents with standard chemotherapeutics increase patient survival.\u003C\u002Fp\u003E"},{article_id:"5118",title:ci,image:m,tag:"35",doi:"10.20517\u002F2394-4722.2022.34",date_published:"1661356800",section:r,authors:"Augusto Valdivia, ... Ana Oaknin",journal_id:j,volume:N,year:w,section_id:m,special_name:a,url_doi:ch,pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F22b36e72-38d5-4599-9fcc-5ca061ae72ce\u002F5118.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Augusto Valdivia'\u003E Augusto Valdivia, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Juan Francisco Grau-Béjar'\u003E Juan Francisco Grau-Béjar, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Carmen García-Durán'\u003E Carmen García-Durán, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Ana Oaknin'\u003E Ana Oaknin",journal_path:d,video_img:a,image_list:m,abstract:"\u003Cp\u003ECervical cancer is the fourth most common cancer in women worldwide, with a global incidence of 604,127 and an annual death rate of 341,831 in 2020. Patients with recurrent, persistent, or metastatic disease not amenable to curative therapy represent a patient population with a dismal prognosis. Until recently, the standard of care for these patients was based on platinum doublet chemotherapy with or without bevacizumab. However, significant advances in the treatment landscape of this disease have recently been achieved with the incorporation, among others, of immunotherapy in the therapeutic armamentarium. This review summarizes the main treatment approaches developed throughout the past decades, with particular emphasis on immunotherapy and novel targeted therapies.\u003C\u002Fp\u003E"},{article_id:"5104",title:"Germline predisposition to soft tissue sarcoma",image:m,tag:"31",doi:"10.20517\u002F2394-4722.2022.31",date_published:"1660838400",section:r,authors:"Jennie Vagher, ... Luke Maese",journal_id:j,volume:N,year:w,section_id:m,special_name:a,url_doi:"2394-4722.2022.31",pdf:"https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F0cdf06a1-200d-4116-8ca3-00443fc04d3e\u002F5104.pdf",video_url:a,allauthors:"\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Jennie Vagher'\u003E Jennie Vagher, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Matthew S. Dietz'\u003E Matthew S. Dietz, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Joshua D. Schiffman'\u003E Joshua D. Schiffman, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Wendy Kohlmann'\u003E Wendy Kohlmann, \u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Fdefault_photo.png' class='author_photo' alt='Luke Maese'\u003E Luke Maese",journal_path:d,video_img:a,image_list:m,abstract:"\u003Cp\u003ESoft tissue sarcoma (STS) most often occurs sporadically, but can also arise in the setting of a germline cancer predisposition syndrome (CPS). There is significant diversity amongst STS diagnoses as these tumors exhibit a variety of histologies, occur in all age groups, and can occur in any location in the body. This diversity is also reflected in the many known associated germline cancer predisposition associations. Some STS diagnoses, such as anaplastic rhabdomyosarcoma, are associated with high heritability and other STS, such as Ewing sarcoma, are notably absent from known CPS. Recognizing when a STS is more likely to be hereditary can influence clinical management. Individuals diagnosed with STS due to CPS may be at risk for other malignancies and should undergo additional surveillance for early detection. Additionally, family members should undergo genetic testing as they also may be at risk to develop STS and other CPS-associated malignancies. Some underlying cancer predisposition diagnoses may have implications for the treatment of a concurrent malignancy as in the case of PARP inhibitor therapy in the setting of homologous recombination deficiency. This review summarizes current knowledge of selected STS and their associations with CPS.\u003C\u002Fp\u003E"}],cited_ids:"4837,5118,5104"},indexFot:{webinars:[],osi:{url:db,img:"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20230831\u002F7ec3774cf8ec4cc0926991c3c2d574c2.jpg",list:[{section_id:2175,journal_id:p,deadline:1747281903,image:"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240812\u002F9c00477f7cff41c3a68f4c68d2521073.jpg",sub_link:"https:\u002F\u002Foaemesas.com\u002Flogin?JournalId=jcmt&SpecialIssueId=jcmt20240812",email:"Grace@oaepublish.com",issue_flyer:a,title:"Topic: Selected Papers from 2nd International Cancer Science Congress (ICSC) 2024",count:k,author:["Prof. Dr. Ciro Isidoro","Prof. Dr. Danny N Dhanasekaran","Prof. Dr. Devrim Gözüaçık"]},{section_id:2252,journal_id:p,deadline:1746849903,image:"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240930\u002F7db3593803a149cb8c537bf4b634ca48.jpg",sub_link:"https:\u002F\u002Foaemesas.com\u002Flogin?JournalId=jcmt&SpecialIssueId=jcmt20240930",email:"Sophia@oaeservice.com",issue_flyer:a,title:"Topic: Innovative Approaches and Prognostic Insights in Oral Cancer Research",count:k,author:["Prof. Giuseppe Minervini ","Dr. Valentina Belli"]}]},editor:[{id:325,name:"Ciro Isidoro",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002FCiroIsidoro-20231229.jpg",href:"http:\u002F\u002Fwww.isidorolab.com\u002Fpublic\u002F"},{id:338,name:"Dai-Ming Fan",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002F3c0c7a58-59a8-4401-a80e-4c447a0a539c\u002FDai-Ming Fan.png",href:"https:\u002F\u002Fwww.scopus.com\u002Fauthid\u002Fdetail.uri?authorId=7202965595"},{id:327,name:"Yan Sun",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002F3699808e-cafb-468f-b231-039c75b050b5\u002FYan Sun.png",href:"http:\u002F\u002F124.17.100.213\u002Facademician\u002F174.html"},{id:3404,name:"Alfio Wo Ferlito",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002F5a8d2eb4-c8db-4ce9-b1f3-a94685eb4ff0\u002FAlfio Ferlito-20240826.jpg",href:"http:\u002F\u002Fwww.ihnsg.com\u002F"},{id:2857,name:"William C Cho",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbd9875cd-d87c-47fd-834c-17893d30a8fa\u002FWilliam C. Cho.jpg",href:"https:\u002F\u002Fwww.proteobiojournal.com\u002Feditors\u002Fwilliam-cs-cho"},{id:3030,name:"Yudong Zhang",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002FJCMT815-20230815.jpg",href:"https:\u002F\u002Fwww.scopus.com\u002Fauthid\u002Fdetail.uri?authorId=35786830100"},{id:3715,name:"Timothy M. Pawlik",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002FTimothy M. Pawlik-20240712.jpg",href:"https:\u002F\u002Fwww.scopus.com\u002Fauthid\u002Fdetail.uri?authorId=7006249269"},{id:349,name:"Gopal C. Kundu",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002FGopalKundu-20231229.jpg",href:"https:\u002F\u002Fbiotech.kiit.ac.in\u002Ffaculties\u002FGopal-C-Kundu.html"},{id:bA,name:"Andrea M. Nicolini",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002F6c2ac55e-814e-466c-bf4c-ff83db1fd85b\u002FAndrea Nicolini.png",href:"https:\u002F\u002Fwww.scopus.com\u002Fauthid\u002Fdetail.uri?authorId=7006511647"},{id:1808,name:"Christos Papadimitriou",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002FChristosPapadimitrio1-20231229.jpg",href:"https:\u002F\u002Fwww.scopus.com\u002Fauthid\u002Fdetail.uri?authorId=35480910300"},{id:328,name:dc,img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002FGodefridus J. Peters-20180807-20220923.jpg",href:"xxx"},{id:1946,name:"John M. Pezzuto",img:"https:\u002F\u002Foaepublishstorage.blob.core.windows.net\u002Fbb82dfd3-42bc-43d7-a2e4-8b8d82ff5d26\u002Fjohn_pezzuto-20211208-20220525.png",href:"https:\u002F\u002Fwww1.wne.edu\u002Fnews\u002F2020\u002F05\u002Fdean-cophs-pezzuto.cfm"},{id:312,name:"Stephen J. 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Issues",url:"\u002Fjcmt\u002Fongoing_special_issues",sort:l},{name:"Completed Special Issues",url:"\u002Fjcmt\u002Fcompleted_special_issues",sort:o},{name:"Closed Special Issue",url:"\u002Fjcmt\u002Fclosed_special_issues",sort:u},{name:"Special Issue Ebooks",url:"\u002Fjcmt\u002Fspecial_issues_ebooks",sort:s},{name:"Special Issue Guidelines",url:"\u002Fjcmt\u002Fspecial_issue_guidelines",sort:j}]},{name:"Volumes",url:"\u002Fjcmt\u002Fvolumes",thispartype:m,sort:j},{name:"Pre-onlines",url:"\u002Fjcmt\u002Fpre_onlines",thispartype:m,sort:bZ},{name:"Features",url:a,thispartype:g,sort:N,children:[{name:"Webinars",url:"\u002Fjcmt\u002Fwebinars",sort:g},{name:"Academic 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Scholar",url:"https:\u002F\u002Fscholar.google.com\u002Fcitations?user=ltC8-6IAAAAJ&hl=zh-CN&authuser=2",icon:"class-google-scholar"}],wechat_img:a,twitter:{url:ld,img:"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20230824\u002Fdec9be8c8dd14eb2a8038ffc72d9d15c.png"}},top:{path:d,pid:p,journal_img:b$,journal_name:M,mpt:"55 days",issn:lc,indexing:{ESCI:"https:\u002F\u002Fmjl.clarivate.com:\u002Fsearch-results?issn=2394-4722&hide_exact_match_fl=true&utm_source=mjl&utm_medium=share-by-link&utm_campaign=search-results-share-this-journal",CAS:"https:\u002F\u002Fcassi.cas.org\u002Fpublication.jsp?P=eCQtRPJo9AQyz133K_ll3zLPXfcr-WXfJmdj1To7iOwfUb0Y4oZXk8VoUIy01BxD0JC2991Ffg3RhGsj2BZ90XEwYimXiG4ZMs9d9yv5Zd85gYyul-WH3u5L9bts2nU3Ms9d9yv5Zd95Y28Wy7la6CF6glzYamsl",Scopus:bg,"Wanfang Data":"https:\u002F\u002Fwww.wanfangdata.com.cn\u002Findex.html?index=true",CNKI:" https:\u002F\u002Fscholar.cnki.net\u002Fjournal\u002Findex\u002FSJWK245428570232",Dimensions:"https:\u002F\u002Fapp.dimensions.ai\u002Fdiscover\u002Fpublication?and_facet_source_title=jour.1149865",Embase:"https:\u002F\u002Fbeta.elsevier.com\u002Fproducts\u002Fembase\u002Fcontent?trial=true"},editor:a,journal_rank:"CiteScore 3.2 - Q3 (Oncology)",journal_flyer:a,qksearch:["Cancer Treatment","Metastasis","Microenvironment","Immunotherapy","Breast Cancer Metastasis","Bone Metastasis","Metastatic Renal Cell Carcinoma","Lymph node metastasis","Mesothelioma","Hematological Malignancies","Thyroid Cancer","Liquid Biopsies","Early Diagnosis","Lung Cancer","Brain Tumors","Lymphoma","Oncolytic Virus","Cervical Cancer","Cancer Stem Cells"],sitetag:"J Cancer Metastasis Treat",ad:[],colour_tag:b_,score:a,mobile_top_img:a,impact_factor:[{factor:cc,url:bg},{factor:cd,url:ce},{factor:h,url:E}],rgba:ca,log_image:cb},webinfo:{},searchKey:a,loading:le,appid:a,videoPlay:{show:aX,href:a}},editer:{editList:{list:{}}},userdata:{showLogin:aX,logined:aX}},serverRendered:le,routePath:bY,config:{_app:{basePath:lf,assetsPath:lf,cdnURL:"https:\u002F\u002Fg.oaes.cc\u002Foae\u002Fnuxt\u002F"}}}}("",null,1,"jcmt",4,"2021","1","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240506\u002Fea3d9071c35b4bf3982ffe25f1083620.png",5,"6",0,"2","0",3,"3",6,2,"Review","5",10,"4",7,"2022",8,"2017",-1,9,"[]","editor001@jcmtjournal.com",40,"https:\u002F\u002Fmjl.clarivate.com\u002Fsearch-results","10","2015",13,32,34,15,20,"Journal of Cancer Metastasis and Treatment","8","Carl.Zhou@jcmtjournal.com","Cancer Drug Resistance","Hepatoma Research",39,55,18,"33","Lens",35,"2020","image","2024","2016",14,65,27,33,22,31,25,19,"dandanyu@oaepublish.com",26,11,16,"Extracellular Vesicles and Circulating Nucleic Acids","Microbiome Research Reports","One Health & Implementation Research","Chemical Synthesis","Energy Materials","Journal of Materials Informatics","Microstructures","Minerals and Mineral Materials","Soft Science","Complex Engineering Systems","Disaster Prevention and Resilience","Green Manufacturing Open","Intelligence & Robotics","Journal of Smart Environments and Green Computing","Journal of Surveillance, Security and Safety","Ageing and Neurodegenerative Diseases","Artificial Intelligence Surgery","Connected Health And Telemedicine","Journal of Translational Genetics and Genomics","Metabolism and Target Organ Damage","Mini-invasive Surgery","Plastic and Aesthetic Research","Rare Disease and Orphan Drugs Journal","The Journal of Cardiovascular Aging","Vessel Plus","Carbon Footprints","Journal of Environmental Exposure Assessment","Water Emerging Contaminants & Nanoplastics","25","https:\u002F\u002Fimage.oaes.cc\u002F82580177-5632-4585-bf24-c54aa1afe386\u002F2275-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002Fa3b828e5-533c-4978-97ab-d1814694982b\u002F1172-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002Febdc743d-8ff2-4cc2-815a-1dd073f7bed8\u002F1713-coverimg.jpg","ivory@jcmtjournal.com",70,68,"olivia@jcmtjournal.com",1640908800,47,false,"11",23,30,24,"ESCI, CAS, Dimensions, Lens, CNKI",17,12,"ESCI, CAS, Scopus, Wanfang Data, CNKI, Dimensions, Embase","39",90,"https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101058912","Journal of Unexplored Medical Data",21,"ESCI, Scopus, CAS, Dimensions, Lens, CNKI","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240809\u002Fccc8ac23b789404781787655e4495af4.png","Neuroimmunology and Neuroinflammation","2014",29,"ISSN XXXX-XXXX (Coming soon)","Soil Health","Space Mission Planning & Operations","Stomatological Disease and Science","29","28","Stanley J. Oiseth, Mohamed S. Aziz","Topic: Cancer Immunotherapy","Pravin D. Potdar\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0001-5151-6697' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Pravin D. Potdar'\u003E\u003C\u002Fa\u003E, Navjeet Kaur Lotey","2019","Topic: Hyponatremia and Cancer","Gao-Feng Xiong, Ren Xu\u003Ca href='https:\u002F\u002Forcid.org\u002F0000-0002-3591-9522' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Ren Xu'\u003E\u003C\u002Fa\u003E",296,417,54,527,1651276800,77,71,"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231113\u002F9db4b73f2e954900807499f00094fcf0.jpg","cdr","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002F4ef51b2e673a40ca9ebf0a414f21adb5.jpg","hr","Guang-Wen Cao",42,58,62,38,"editorialoffice@jcmtjournal.com",83,103,49,45,104,81,"Contact Us","\u002Fjcmt","7","#44b762","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231121\u002Fe46043c3fcaf49f38eef7654adff79e1.jpg","rgb(68,183,98)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fjcmt.jpg","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231201\u002F8b13deaaf6e24f9189ca91e62e3b84ab.png","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240621\u002F38a515f5996349019b5018be997f4446.png","https:\u002F\u002Fmjl.clarivate.com\u002F","2394-4722.2022.08","Anti-angiogenic drugs in cancer therapeutics: a review of the latest preclinical and clinical studies of anti-angiogenic agents with anticancer potential","2394-4722.2022.34","Treatment strategies in cervical cancer: treatment of advanced disease",385,"https:\u002F\u002Fv.oaes.cc\u002Fuploads\u002F20240724\u002F37b2372a5b3640f3876df3a4bca2f1ac.mp4","https:\u002F\u002Fimage.oaes.cc\u002Fa3977867-04b2-4394-9124-abaa22312794\u002Fjcmt4063-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002Fafa220a7-79b5-4ced-9cf2-1f492c138c90\u002Fjcmt10078-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002F27820a4f-7eeb-4057-8aae-97c2894b0758\u002Fjcmt4076-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002F84b27e36-8a10-4a22-9aa0-921083f19098\u002Fjcmt10040-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002Fc861a518-8526-4722-a8ef-68961bd73500\u002Fjcmt4052-coverimg.jpg","https:\u002F\u002Fimage.oaes.cc\u002Faacf921e-f663-4c76-ba32-4ba5f19590d9\u002F1263-coverimg.jpg","2275","Cancer immunotherapy: a brief review of the history, possibilities, and challenges ahead","250-61","10.20517\u002F2394-4722.2017.41","1509379200","126","2394-4722.2017.41","https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F82580177-5632-4585-bf24-c54aa1afe386\u002F2275.pdf","\u003Cp\u003E The knowledge that the body possesses natural defenses to combat cancer existed long before the modern period, with multiple anecdotal reports of tumors miraculously disappearing, sometimes spontaneously or after a febrile or infectious episode. Spontaneous tumor regression of untreated malignant tumors is currently a well-accepted albeit rare phenomenon, and it is recognized that immunosuppression is associated with a higher cancer risk. The treatment of bladder carcinoma by intravesical administration of live attenuated Bacillus Calmette-Guérin bacteria was shown to be very effective in 1976 and is now standard treatment. Effective immunity against cancer involves complex interactions between the tumor, the host, and the environment. Cancer immunotherapy uses various strategies to augment tumor immunity and represents a paradigm shift in treating cancer, since attention has become more focused on the “biologic passport” of the individual tumor rather than the site of origin of the tumor. The different types of cancer immunotherapies discussed here include biologic modifiers, such as cytokines and vaccines, adoptive cell therapies, oncolytic viruses, and antibodies against immune checkpoint inhibitors, such as the co-inhibitory T-cell receptor PD-1 and one of its ligands, programmed death-ligand 1. \u003C\u002Fp\u003E","1172","Role of circulating tumor cells in future diagnosis and therapy of cancer","44-56","10.4103\u002F2394-4722.158803","1436889600","2394-4722.158803","https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002Fa3b828e5-533c-4978-97ab-d1814694982b\u002F1172.pdf","\u003Cp\u003E Circulating tumor cells (CTCs) have become a blistering topic of discussion for oncologists because of their tremendous potential in the diagnosis and treatment of cancer. Over the past few years, they have been doled with quite an amount of research in this area understanding that CTCs are shed from tumors and circulate in the bloodstream. This process can also occur at an early stage of cancer. The major limitation in isolation of CTCs is their availability in limited numbers. Hence, many techniques have been developed and are under continuous improvement to enhance their efficacy of CTC isolation and enumeration. They have shown their potentiality to not just indicate the presence of a tumor but also to provide us with its core information. They have also proven to be useful in detecting minor subgroups of cells present in the primary tissue which might eventually be the cause of treatment resistance or relapse of the disease. Hence, detecting and characterizing CTCs can definitely become an inevitable step in treating solid tumor malignancies. In this review, we have tried to comprehend the basics of CTCs including isolation, detection, characterization, and molecular mechanism of their circulation in the blood stream. We have mostly focused on the significance of CTCs in diagnosis and therapies of four most common types of cancers, namely, breast, prostate, lung, and colorectal. This review provides the coverage of most of the advancements with regards to different tumor malignancies and their probable use in predicting outcomes of the disease to realize the concept of personalized medicine. \u003C\u002Fp\u003E","3279","Electrolyte disorders in cancer patients: a systematic review","79","10.20517\u002F2394-4722.2019.008","1575820800","Rossana Berardi\u003Ca href='https:\u002F\u002Fwww.researchgate.net\u002Flab\u002FRossana-Berardi-Lab' target='_blank'\u003E\u003Cimg src='https:\u002F\u002Fi.oaes.cc\u002Fimages\u002Forcid.png' class='author_id' alt='Rossana Berardi'\u003E\u003C\u002Fa\u003E, ... Silvia Rinaldi","164","2394-4722.2019.008","https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002F43240062-53d7-4003-b0a6-f7c9abd1e595\u002F3279.pdf","\u003Cp\u003EElectrolyte disorders are very common complications in cancer patients. They might be associated to a worsening outcome, influencing quality of life, possibility to receive anticancer drugs, and conditioning survival. In fact, they might provoke important morbidity, with dysfunction of multiple organs and rarely causing life-threatening conditions. Moreover, recent studies showed that they might worsen cancer patients’ outcome, while a prompt correction seems to have a positive impact. Furthermore, there is evidence of a correlation between electrolyte alterations and poorer performance status, delays in therapy commencement and continuation, and negative treatment outcomes. These alterations usually involve sodium, potassium, calcium, and magnesium serum levels. Several causes might contribute to electrolyte disorders in cancer patients: cancer effects, such as paraneoplastic syndrome of inappropriate antidiuresis and tumor lysis syndrome; anti-cancer therapies; and other concomitant clinical conditions or treatments. However, the origin of the electrolyte disorder is often multifactorial, thus identifying and correcting the causes is not always feasible. Furthermore, they are often not recognized or not considered in clinical practice, worsening these alterations and patient condition. An improvement of knowledge about the physiological mechanisms underlying electrolyte disorders is necessary to strengthen their identification and set up a prompt, adequate, and effective treatment. The aim of this systematic review is to provide an analysis of the pathophysiological mechanisms of electrolyte abnormalities in cancer patients to facilitate their identification, management, and therapy to improve patient outcome.\u003C\u002Fp\u003E","1713","Function of cancer cell-derived extracellular matrix in tumor progression","357-64","10.20517\u002F2394-4722.2016.08","1474128000","2394-4722.2016.08","https:\u002F\u002Ff.oaes.cc\u002Fxmlpdf\u002Febdc743d-8ff2-4cc2-815a-1dd073f7bed8\u002F1713.pdf","\u003Cp\u003EExtracellular matrix (ECM) is an essential component of the tumor microenvironment. Cancer development and progression are associated with increased ECM deposition and crosslink. The chemical and physical signals elicited from ECM are necessary for cancer cell proliferation and invasion. It is well recognized that stromal cells are a major source of ECM proteins. However, recent studies showed that cancer cells are also an active and important component in ECM remodeling. Cancer cells deposit a significant amount of collagen, fibronectin, and tenascin C (TNC). Recent studies demonstrate that these cancer cell-derived ECM proteins enhance cancer cell survival and promote cancer cell colonization at distant sites. ECM-related enzymes and chaperone proteins, such as prolyl-4-hydroxylase, lysyl-hydroxylase, lysyl oxidase, and heat shock protein 47, are also highly expressed in cancer cells. Inhibition of these enzymes significantly reduces cancer growth, invasion, and metastasis. These factors suggest that the cancer cell-derived ECM is crucial for cancer progression and metastasis. Therefore, targeting these ECM proteins and ECM-related enzymes is a potential strategy for cancer treatment. \u003C\u002Fp\u003E","https:\u002F\u002Fimage.oaes.cc\u002F795916d5-fa0f-4f76-99c1-1397d98796c4\u002F3026-coverimg.jpg","Topic: Breast Cancer Metastasis","https:\u002F\u002Fimage.oaes.cc\u002F1858ce41-479a-4354-b623-967f60362200\u002F4837-coverimg.jpg","https:\u002F\u002Foaemesas.com\u002Flogin?JournalId=jcmt","Godefridus J. Peters",355,526,1656547200,"https:\u002F\u002Fi.oaes.cc\u002Fpublic\u002Fissue_special\u002F526\u002F62_jcmt_sp526.jpg","Topic: Lymph Node Metastases in the Neck",876,"https:\u002F\u002Fi.oaes.cc\u002Fpublic\u002Fissue_special\u002F876\u002F59_111.jpg","Topic: Treatment of Pancreatic Cancer",67,"gladys@jcmtjournal.com",1569801600,"Prof. Rossana Berardi",1532995200,"Prof. Masayuki Watanabe","About","Editorial Policies","Journals","Biology & Life Science","Chemistry & Materials Science","Computer Science & Engineering","Medicine & Public Health","9","12","Environmental Science","#837fbc","ISSN 2769-5301 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231218\u002F6135b005a8674b878a7d1a5c91ac9869.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fand","Wei-Dong Le","CAS, Dimensions, Lens, CNKI","rgb(99,94,171)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fand.jpg","and","#030072","ISSN 2771-0408 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002F14bc775310574f91b457ff09d6c6d950.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fais","Andrew A. Gumbs","36","ESCI, Scopus, Dimensions, Lens","rgb(3,0,114)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fais.png","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240813\u002Fb7358d0632aa413fa84630ef0a2fb7a0.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101189039","ais","#e8b475","ISSN 2578-532X (Online)","https:\u002F\u002Fwww.oaepublish.com\u002Fcdr","Godefridus J. (Frits) Peters","2018","337","ESCI, PMC, Scopus, CAS, CNKI, Dimensions, Lens, Embase","rgb(224,155,71)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fcdr.jpg","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240104\u002F502e35965fc448e0bc9f2d6c1b0bb3d7.png","https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Fjournals\u002F4180\u002F","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240611\u002F5def3ab5829743ce8d55e664cabe0dcb.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101047803","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240620\u002Fed79fcbfce8e4cd38a36cc4d5f7d473d.png","https:\u002F\u002Fjcr.clarivate.com\u002Fjcr-jp\u002Fjournal-profile?journal=CANCER%20DRUG%20RESIST&year=2022","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240620\u002F86311aafb7a945a98a7ee95c3627173b.png","#1d57a5","ISSN 2770-6249 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fimages_2018\u002Foae\u002Fcover_comengsys.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fcomengsys","Hamid Reza Karimi","37","Scopus, Dimensions, Lens","rgb(29,87,165)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fces.png","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240722\u002F4748814aab87441d809e5b9ddcd9d56e.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101189038","comengsys","#75ac9d","ISSN 2993-2920 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231218\u002F0b7a80c0f6e545818e143ea48fe9be90.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fchatmed","Yuan-Ting Zhang","20","rgb(117, 172, 157)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fchatmed.jpg","chatmed","#00a5b3","ISSN 2769-5247 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231121\u002F1598f33bf2284642830511e489eb31bf.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fcs","Bao-Lian Su","67","Scopus, CAS, Dimensions, Lens, CNKI","rgb(0,165,179)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fcs.jpg","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240813\u002F6d91bea2ff474cb9b7ec10017b26ec2a.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101189036","cs",157,51,"#6cc24a","ISSN 2831-932X (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002Fb1a3c337f6a54bcb945e0d9ab6afe0ec.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fcf","Yong Geng","16","rgb(86,164,55)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fcf.jpg","cf","#01588b","ISSN 2832-4056 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002Fe5808de306274ba287f6f24bf45eb910.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fdpr","Jie Li","14","rgb(1,88,139)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fdpr.jpg","dpr","#008c15","ISSN 2770-5900 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Lens","rgb(123,164,219)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fmrr.jpg",101,"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240104\u002F206342e31750460bb7449112e6aafba6.png","https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Fjournals\u002F4522\u002F","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240621\u002F1dfbaaeea68e40c98d7494b8c702b695.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101195678?origin=resultslist","https:\u002F\u002Fwww.oaepublish.com\u002Fnews\u002Fmrr.836","mrr",117,"#6f7bd4","ISSN 2770-2995 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231113\u002F1738c68b2d0a41edae268adf4ea5c7e2.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fmicrostructures","Shujun Zhang","53","ESCI, Scopus, CAS, Dimensions, 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Martin-Moreno","rgb(67,176,42)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fohir.jpg",105,"ohir","#c45284","ISSN 2349-6150 (Online)\u003Cbr\u003EISSN 2347-9264 (Print)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002F8d72c3f669d5490ea3b9abc424d66cb6.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fpar","Wen-Guo Cui","520","rgb(196,82,132)","ESCI, Scopus, Dimensions, CNKI, Lens, Wanfang","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fpar.jpg","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240607\u002F9bbbcad710cf457e85d63b1811faefb1.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101111784","https:\u002F\u002Fclarivate.com\u002Fproducts\u002Fscientific-and-academic-research\u002Fresearch-discovery-and-workflow-solutions\u002Fwebofscience-platform\u002Fweb-of-science-core-collection\u002Femerging-sources-citation-index\u002F","par",619,"#d62598","ISSN 2771-2893 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231121\u002F6ee75e8ab583446b90c97865c2c68464.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Frdodj","Daniel Scherman","Dimensions, Lens","rgb(214,37,152)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Frdodj.jpg",106,"rdodj","#1f4e79","ISSN 2769-5441 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002F98e2ed5023ee466c8890d749bfd97597.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fss","YongAn Huang","58","ESCI, Scopus, CAS, Lens, Dimensions, CNKI","rgb(31,78,121)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fss.jpg",107,"https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240606\u002Fcfa200290630438c8e3a3cae1536af37.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101178114","ss",116,"#a96318","https:\u002F\u002Fi.oaes.cc\u002Fimages_2018\u002Foae\u002Fcover_sh.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fsh","Manoj Shukla","rgb(169,99,24)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fsh.jpg",108,"sh","#4475e1","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231218\u002F79ccda0bc909441587a0b70e0a8ef1cc.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fsmpo","Madjid Tavana","rgb(68,117,225)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fsmpo.jpg",109,"smpo","#53be9b","ISSN 2573-0002 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231218\u002F54ba11ec5c57448a84169c318bb94fd4.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fsds","Nikolaos G. Nikitakis","40","rgb(62,163,130)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fsds.jpg",110,"sds","#0038a0","ISSN 2768-5993 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231113\u002F695c0f0de82c43f189957ff572f0798c.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fjca","89","rgb(0,56,160)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fjca.png","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240611\u002Fd7d617bceee246428da2ed07a84efd5e.png","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101176723","https:\u002F\u002Fwww.oaepublish.com\u002Fnews\u002Fjca.838","jca",129,36,"#db6868","ISSN 2574-1209 (Online)","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20231110\u002Fe64051237c8a454085bb02abfdc6dd12.jpg","https:\u002F\u002Fwww.oaepublish.com\u002Fvp","290","CAS, Scopus, CNKI, Dimensions, Lens","rgb(219,104,104)","https:\u002F\u002Fi.oaes.cc\u002Fupload\u002Fjournal_logo\u002Fvp.jpg","https:\u002F\u002Fi.oaes.cc\u002Fuploads\u002F20240606\u002Fa5cb40102c2d4ec4b1a362fe1f27d324.jpg","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101064905","vp",351,"5555","\u002Fjcmt\u002Fcontact_us","For Authors","2454-2857 (Online) 2394-4722 (Print)","https:\u002F\u002Ftwitter.com\u002FOAE_JCMT",true,"\u002F"));</script><script src="https://g.oaes.cc/oae/nuxt/b06ddfb.js" defer></script><script src="https://g.oaes.cc/oae/nuxt/dce480e.js" defer></script><script src="https://g.oaes.cc/oae/nuxt/fc5a5cb.js" defer></script><script src="https://g.oaes.cc/oae/nuxt/0a3b980.js" defer></script><script src="https://g.oaes.cc/oae/nuxt/3e8004d.js" defer></script><script src="https://g.oaes.cc/oae/nuxt/b19d7ea.js" defer></script> </body> </html> <div id="noIe" style="display: none;"> <style> #noIe { background: rgba(99, 125, 255, 1); width: 100%; height: 100vh; position: fixed; top: 0; left: 0; z-index: 999999; } #noIe .container { width: 802px; height: 594px; background: #ffffff; border-radius: 10px; position: absolute; left: 50%; margin-left: -401px; margin-top: -297px; top: 50%; text-align: center; } #noIe .container ul { display: inline-block; height: 164px; margin-left: -30px; margin-top: 100px; } #noIe .container li { float: left; list-style: none; text-align: center; margin-left: 30px; } #noIe li img { width: 115px; height: 115px; } #noIe li p { margin-top: 12px; font-size: 14px; line-height: 150%; font-weight: 500; color: #526efa; } #noIe a { text-decoration: none; } #noIe li p a:visited { color: #526efa; } #noIe li p.tip { font-size: 10px; line-height: 160%; font-weight: normal; text-align: center; margin-top: 0; color: rgba(37, 38, 43, 0.36); } #noIe .title { margin-top: 72px; font-size: 36px; line-height: 140%; font-weight: bold; color: #25262b; } #noIe .title2 { margin-top: 7px; font-size: 14px; line-height: 170%; color: #25262b; } #noIe .logo-container { width: 100%; text-align: center; padding-top: 100px; } #noIe .logo { height: 24px; } @media screen and (max-width: 820px) { #noIe .container { width: 432px; left: 50%; margin-left: -216px; margin-top: 48px; position: relative; top: 0; } #noIe .container ul { width: 290px; height: 352px; margin-left: -30px; margin-top: 40px; } #noIe .container li { margin-left: 30px; margin-top: 24px; } #noIe .logo-container { padding-top: 121px; padding-bottom: 20px; } } </style> <div class="container"> <p class="title">The current browser is not compatible</p> <p class="title2">The following browsers are recommended for the best use experience</p> <ul> <li> <a href="https://www.google.cn/chrome/" target="_blank"> <img src="https://gw.alicdn.com/imgextra/i2/O1CN01Nn0IoE1cmXZ6gFiM3_!!6000000003643-2-tps-230-230.png" /> <p>Chrome</p> </a> </li> <li> <a href="http://www.firefox.com.cn/" target="_blank"> <img src="https://gw.alicdn.com/imgextra/i3/O1CN01P8aqdX1HdHczGialK_!!6000000000780-2-tps-230-230.png" /> <p>Firefox</p> </a> </li> <li> <a href="https://www.apple.com/safari/" target="_blank"> <img src="https://gw.alicdn.com/imgextra/i4/O1CN01vVxDF11chVD0nsbiZ_!!6000000003632-2-tps-230-230.png" /> <p>Safari</p> <p class="tip">Only supports Mac</p> </a> </li> <li> <a href="https://www.microsoft.com/zh-cn/edge" target="_blank"> <img src="https://gw.alicdn.com/imgextra/i4/O1CN01UW7hs31Xa6jfm2a2O_!!6000000002939-2-tps-230-230.png" /> <p>Edge</p> </a> </li> </ul> <div class="logo-container"> <img 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