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Ribonuclease – Wikipédia, a enciclopédia livre

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</div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Ribonuclease</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ir para um artigo noutra língua. Disponível em 34 línguas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-34" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">34 línguas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%B1%D9%8A%D8%A8%D9%88%D9%86%D9%88%D9%83%D9%84%D9%8A%D8%A7%D8%B2" title="ريبونوكلياز — árabe" lang="ar" hreflang="ar" data-title="ريبونوكلياز" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Ribonukleaza" title="Ribonukleaza — bósnio" lang="bs" hreflang="bs" data-title="Ribonukleaza" data-language-autonym="Bosanski" data-language-local-name="bósnio" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Ribonucleasa" title="Ribonucleasa — catalão" lang="ca" hreflang="ca" data-title="Ribonucleasa" data-language-autonym="Català" data-language-local-name="catalão" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/RN%C3%A1za" title="RNáza — checo" lang="cs" hreflang="cs" data-title="RNáza" data-language-autonym="Čeština" data-language-local-name="checo" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Ribonukleasen" title="Ribonukleasen — alemão" lang="de" hreflang="de" data-title="Ribonukleasen" data-language-autonym="Deutsch" data-language-local-name="alemão" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Ribonuclease" title="Ribonuclease — inglês" lang="en" hreflang="en" data-title="Ribonuclease" data-language-autonym="English" data-language-local-name="inglês" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Ribonucleasa" title="Ribonucleasa — espanhol" lang="es" hreflang="es" data-title="Ribonucleasa" data-language-autonym="Español" data-language-local-name="espanhol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Erribonukleasa" title="Erribonukleasa — basco" lang="eu" hreflang="eu" data-title="Erribonukleasa" data-language-autonym="Euskara" data-language-local-name="basco" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%B1%DB%8C%D8%A8%D9%88%D9%86%D9%88%DA%A9%D9%84%D8%A6%D8%A7%D8%B2" title="ریبونوکلئاز — persa" lang="fa" hreflang="fa" data-title="ریبونوکلئاز" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Ribonukleaasi" title="Ribonukleaasi — finlandês" lang="fi" hreflang="fi" data-title="Ribonukleaasi" data-language-autonym="Suomi" data-language-local-name="finlandês" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Ribonucl%C3%A9ase" title="Ribonucléase — francês" lang="fr" hreflang="fr" data-title="Ribonucléase" data-language-autonym="Français" data-language-local-name="francês" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Ribonuclease" title="Ribonuclease — galego" lang="gl" hreflang="gl" data-title="Ribonuclease" data-language-autonym="Galego" data-language-local-name="galego" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/RNase" title="RNase — hebraico" lang="he" hreflang="he" data-title="RNase" data-language-autonym="עברית" data-language-local-name="hebraico" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Ribonukleaza" title="Ribonukleaza — croata" lang="hr" hreflang="hr" data-title="Ribonukleaza" data-language-autonym="Hrvatski" data-language-local-name="croata" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Ribonukle%C3%A1z" title="Ribonukleáz — húngaro" lang="hu" hreflang="hu" data-title="Ribonukleáz" data-language-autonym="Magyar" data-language-local-name="húngaro" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%8C%D5%AB%D5%A2%D5%B8%D5%B6%D5%B8%D6%82%D5%AF%D5%AC%D5%A5%D5%A1%D5%A6%D5%B6%D5%A5%D6%80" title="Ռիբոնուկլեազներ — arménio" lang="hy" hreflang="hy" data-title="Ռիբոնուկլեազներ" data-language-autonym="Հայերեն" data-language-local-name="arménio" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Ribonuklease" title="Ribonuklease — indonésio" lang="id" hreflang="id" data-title="Ribonuklease" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonésio" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Ribonucleasi" title="Ribonucleasi — italiano" lang="it" hreflang="it" data-title="Ribonucleasi" data-language-autonym="Italiano" data-language-local-name="italiano" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%AA%E3%83%9C%E3%83%8C%E3%82%AF%E3%83%AC%E3%82%A2%E3%83%BC%E3%82%BC" title="リボヌクレアーゼ — japonês" lang="ja" hreflang="ja" data-title="リボヌクレアーゼ" data-language-autonym="日本語" data-language-local-name="japonês" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%A0%D0%B8%D0%B1%D0%BE%D0%BD%D1%83%D0%BA%D0%BB%D0%B5%D0%B0%D0%B7%D0%B0%D0%BB%D0%B0%D1%80" title="Рибонуклеазалар — cazaque" lang="kk" hreflang="kk" data-title="Рибонуклеазалар" data-language-autonym="Қазақша" data-language-local-name="cazaque" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EB%A6%AC%EB%B3%B4%EB%89%B4%ED%81%B4%EB%A0%88%EC%9D%B4%EC%8A%A4" title="리보뉴클레이스 — coreano" lang="ko" hreflang="ko" data-title="리보뉴클레이스" data-language-autonym="한국어" data-language-local-name="coreano" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Ribonukle%C4%81ze" title="Ribonukleāze — letão" lang="lv" hreflang="lv" data-title="Ribonukleāze" data-language-autonym="Latviešu" data-language-local-name="letão" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Ribonuklease" title="Ribonuklease — malaio" lang="ms" hreflang="ms" data-title="Ribonuklease" data-language-autonym="Bahasa Melayu" data-language-local-name="malaio" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Ribonuclease" title="Ribonuclease — neerlandês" lang="nl" hreflang="nl" data-title="Ribonuclease" data-language-autonym="Nederlands" data-language-local-name="neerlandês" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Ribonuklease" title="Ribonuklease — norueguês nynorsk" lang="nn" hreflang="nn" data-title="Ribonuklease" data-language-autonym="Norsk nynorsk" data-language-local-name="norueguês nynorsk" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Ribonuklease" title="Ribonuklease — norueguês bokmål" lang="nb" hreflang="nb" data-title="Ribonuklease" data-language-autonym="Norsk bokmål" data-language-local-name="norueguês bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Ribonucleasa" title="Ribonucleasa — occitano" lang="oc" hreflang="oc" data-title="Ribonucleasa" data-language-autonym="Occitan" data-language-local-name="occitano" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Rybonukleazy" title="Rybonukleazy — polaco" lang="pl" hreflang="pl" data-title="Rybonukleazy" data-language-autonym="Polski" data-language-local-name="polaco" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A0%D0%B8%D0%B1%D0%BE%D0%BD%D1%83%D0%BA%D0%BB%D0%B5%D0%B0%D0%B7%D1%8B" title="Рибонуклеазы — russo" lang="ru" hreflang="ru" data-title="Рибонуклеазы" data-language-autonym="Русский" data-language-local-name="russo" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Ribonuclease" title="Ribonuclease — Simple English" lang="en-simple" hreflang="en-simple" data-title="Ribonuclease" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Ribonukleaza" title="Ribonukleaza — sérvio" lang="sr" hreflang="sr" data-title="Ribonukleaza" data-language-autonym="Српски / srpski" data-language-local-name="sérvio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Ribon%C3%BCkleaz" title="Ribonükleaz — turco" lang="tr" hreflang="tr" data-title="Ribonükleaz" data-language-autonym="Türkçe" data-language-local-name="turco" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A0%D0%B8%D0%B1%D0%BE%D0%BD%D1%83%D0%BA%D0%BB%D0%B5%D0%B0%D0%B7%D0%B0" title="Рибонуклеаза — ucraniano" lang="uk" hreflang="uk" data-title="Рибонуклеаза" data-language-autonym="Українська" data-language-local-name="ucraniano" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E6%A0%B8%E7%B3%96%E6%A0%B8%E9%85%B8%E9%85%B6" title="核糖核酸酶 — chinês" lang="zh" hreflang="zh" data-title="核糖核酸酶" data-language-autonym="中文" data-language-local-name="chinês" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q422523#sitelinks-wikipedia" title="Editar hiperligações interlínguas" class="wbc-editpage">Editar hiperligações</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espaços nominais"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a 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vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Aspeto</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">mover para a barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">ocultar</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Origem: Wikipédia, a enciclopédia livre.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="pt" dir="ltr"><figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Ficheiro:RNase_A.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/RNase_A.png/220px-RNase_A.png" decoding="async" width="220" height="170" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/RNase_A.png/330px-RNase_A.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5b/RNase_A.png/440px-RNase_A.png 2x" data-file-width="3652" data-file-height="2821" /></a><figcaption>Estrutura da RNase A</figcaption></figure> <p><b>Ribonuclease</b> (geralmente abreviada como <b>RNase</b>) é um tipo de <a href="/wiki/Nuclease" title="Nuclease">nuclease</a> que <a href="/wiki/Cat%C3%A1lise" title="Catálise">catalisa</a> a degradação do <a href="/wiki/RNA" class="mw-redirect" title="RNA">RNA</a> em componentes menores. As ribonucleases podem ser divididas em <a href="/w/index.php?title=Endorribonuclease&amp;action=edit&amp;redlink=1" class="new" title="Endorribonuclease (página não existe)">endorribonucleases</a> e <a href="/w/index.php?title=Exorribonuclease&amp;action=edit&amp;redlink=1" class="new" title="Exorribonuclease (página não existe)">exorribonucleases</a> e em várias subclasses, dentro da classificação EC das <a href="/wiki/Enzima" title="Enzima">enzimas</a>: EC 2.7 (para as <a href="/w/index.php?title=Fosfotransferase&amp;action=edit&amp;redlink=1" class="new" title="Fosfotransferase (página não existe)">fosfotransferases</a>) e EC 3.1 (para as <a href="/wiki/Hidrolase" title="Hidrolase">hidrolases</a>). </p> <div class="mw-heading mw-heading2"><h2 id="Referências"><span id="Refer.C3.AAncias"></span>Referências</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ribonuclease&amp;veaction=edit&amp;section=1" title="Editar secção: Referências" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Ribonuclease&amp;action=edit&amp;section=1" title="Editar código-fonte da secção: Referências"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> </div> <ul><li>D'Alessio G &amp; Riordan JF, eds. (1997) <i>Ribonucleases: Structures and Functions</i>, Academic Press.</li> <li>Gerdes K, Christensen SK &amp; Lobner-Olesen A (2005). "Prokaryotic toxin-antitoxin stress response loci". Nat. Rev. Microbiol. (3): 371–382.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Ligações_externas"><span id="Liga.C3.A7.C3.B5es_externas"></span>Ligações externas</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ribonuclease&amp;veaction=edit&amp;section=2" title="Editar secção: Ligações externas" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Ribonuclease&amp;action=edit&amp;section=2" title="Editar código-fonte da secção: Ligações externas"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://www.chem.qmul.ac.uk/iubmb/enzyme/EC3/1/">IUBMB <i>Enzyme Database for EC 3.1</i></a></li> <li><a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/intenz/query?cmd=SearchEC&amp;ec=3.1"><i>Integrated Enzyme Database for EC 3.1</i></a></li></ul> <table class="noprint" style="border-top:none; border-bottom:none; background:transparent; color: inherit"><tbody><tr> <td style="text-align: center;"><span typeof="mw:File"><a href="/wiki/Ficheiro:3s4eskrp1.png" class="mw-file-description"><img alt="Ícone de esboço" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/3s4eskrp1.png/50px-3s4eskrp1.png" decoding="async" width="50" height="38" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/3s4eskrp1.png/75px-3s4eskrp1.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/3s4eskrp1.png/100px-3s4eskrp1.png 2x" data-file-width="676" data-file-height="514" /></a></span></td> <td><i>Este artigo sobre <a href="/wiki/Bioqu%C3%ADmica" title="Bioquímica">Bioquímica</a> é um <a href="/wiki/Wikip%C3%A9dia:Esbo%C3%A7o" title="Wikipédia:Esboço">esboço</a>. 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