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PEGS Europe Keynotes | Protein & Antibody Engineering Summit | 5-7 November 2024
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<div class="main-content"> <div id="cph1" class="container internal"> <div class="row"> <div class="row" data-sf-element="Row"> <div class="col-sm-9"> <div id="Contentplaceholder1_T14051A0F003_Col00" class="sf_colsIn pad-lr" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div > <div class="sf-Long-text" ><p class="Header">2024 PLENARY DEEP DIVE</p><p><img src="/images/default-source/speakerphotos/klein_christian-jpg_ae117b32-f94e-44f1-8726-5734a8f02bfa.jpg?sfvrsn=5f3f39_52" alt="Christian Klein" class="SpeakerFl" /><b>Chairperson's Remarks</b><br /><i>Christian Klein, PhD, CXO in Residence & Drug Hunter, Curie.Bio</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/arora_taruna-jpg_4c38d25a-22b8-43dd-b765-67592b059f87.jpg?sfvrsn=9809100_3" class="SpeakerFl" alt="Taruna Arora" /><b>Immunotherapy Highlights </b><b> </b><br /><i>Taruna Arora, PhD, Formerly Vice President, Biotherapeutics, Bristol Myers Squibb</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/igawa_tomoyuki-jpg_b10378cc-2643-471b-a1fa-1220d63de761.jpg?sfvrsn=85403fb6_1" class="SpeakerFl" alt="Tomoyuki Igawa" /><b>Multispecific Antibody Highlights </b><br /><i>Tomoyuki Igawa, PhD, Vice President, Discovery Research Division, </i><i>Chugai Pharmaceutical Co.,Ltd</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/matsunaga_hironori-jpg_a1c0f6b1-1b55-4bcc-8fe5-89df7a5e7646.jpg?sfvrsn=3395bd3b_1" class="SpeakerFl" alt="Hironori Matsunaga" /><b>ADC Highlights </b><br /><i>Hironori Matsunaga, PhD, Scientist, Discovery Research Lab I Group II, Daiichi Sankyo Co., Ltd.</i></p><br clear="all" /><p class="Header">2024 Track Keynotes</p><p><img src="/images/default-source/speakerphotos/hagemann_urs-jpg_4013c1a0-7f7e-4f61-abcf-f3ce7a520d59.jpg?sfvrsn=cc6d8e98_1" class="SpeakerFl" alt="Urs B. Hagemann" sf-size="46028" /><b>Considerations for the Successful Development of Targeted Radiotherapies</b><br /><i>Urs B. Hagemann, PhD, Head, Targeted Radiopharmaceuticals, Research & Early Development Oncology, Bayer AG</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/vazquez-lombardi_rodrigo-jpg_e9ea710f-abd4-4800-82e4-831e2ab5ad04.jpg?sfvrsn=c13e390b_16" class="SpeakerFl" alt="Rodrigo Vazquez-Lombardi" sf-size="132329" /><b>Design and Engineering of TCR-Based Immune Cell Engagers for Solid Tumour Indications</b><br /><i>Rodrigo Vazquez-Lombardi, PhD, Co-Founder & CSO, Engimmune Therapeutics AG</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/keyt_bruce-jpg_b41be3ae-3a84-4cb1-92ed-6c12e97199e2.jpg?sfvrsn=e29faffd_30" class="SpeakerFl" alt="Bruce Keyt" sf-size="79768" /><b>Aplitabart, an Anti-DR-5 IgM Antibody for Treatment of Colorectal Carcinoma</b><br /><i>Bruce Keyt, PhD, CSO, R&D, IGM Biosciences, Inc.</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/barth_patrick-jpeg_322293f4-8af8-47fe-b25e-0c8c127ae968.jpeg?sfvrsn=b4dad462_1" class="SpeakerFl" alt="Patrick Barth" sf-size="130061" /><b>Computational Design of Membrane Protein Structures, Functions, and Therapeutics</b><b> </b><br /><i>Patrick Barth, PhD, Associate Professor, Protein and Cell Engineering, EPFL</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/fontana_elisa-jpg_f7ef9c5d-5abd-4dab-babc-a79f0262b11d.jpg?sfvrsn=a52d1eb_2" class="SpeakerFl" alt="Elisa Fontana" sf-size="93804" /><b>Understanding, Predicting, and Mitigating Toxicities with ADCs and Bispecifics</b><b> </b><br /><i>Elisa Fontana, MD, PhD, Oncologist and Medical Director, Sarah Cannon Research Institute UK</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/schuurman_janine-jpg_efc4e609-05d7-4b84-b37a-a2a4e6ff88d4.jpg?sfvrsn=4813ad59_18" class="SpeakerFl" alt="Janine Schuurman" sf-size="121550" /><b>Fireside Chat: The Science and Business of Bispecific Antibodies</b><br />Moderator:<br /><i>Janine Schuurman, PhD, Biotech Consultant, Lust for Life Science B.V.</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/dahiyat_bassil-png_f37b935c-19e0-4280-8e15-cc3332f4e712.png?sfvrsn=269bd1ce_1" class="SpeakerFl" alt="Bassil I. Dahiyat" sf-size="100115" />Panelists:<br /><i>Bassil I. Dahiyat, PhD, CEO, Xencor Inc.</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/logtenberg_ton-jpg_4eccf9a2-8ad7-4341-be29-9feb2331c005.jpg?sfvrsn=5b1bbae6_1" class="SpeakerFl" alt="Ton Logtenberg" sf-size="93267" /><i>Ton Logtenberg, PhD, Former CEO & Executive Director, Merus NV</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/igawa_tomoyuki-jpg_b10378cc-2643-471b-a1fa-1220d63de761.jpg?sfvrsn=85403fb6_1" class="SpeakerFl" alt="Tomoyuki Igawa" sf-size="89553" /><b>Broadly-Reactive Antibody against Multiple Gluten Peptide, HLA-DQ2.5 Complexes for the Treatment of Celiac Disease</b><br /><i>Tomoyuki Igawa, PhD, Vice President, Discovery Research Division, </i>Chugai Pharmaceutical Co.,Ltd</p><br clear="all" /><p><img src="/images/default-source/speakerphotos/klein_christian-jpg_ae117b32-f94e-44f1-8726-5734a8f02bfa.jpg?sfvrsn=5f3f39_52" class="SpeakerFl" alt="Christian Klein" sf-size="103079" /><b>The Present and Future of Bispecific Antibodies for Cancer Therapy</b><br /><i>Christian Klein, PhD, Head, Oncology Programs and Department Head, Cancer Immunotherapy Discovery, Roche Innovation Center Zurich, Roche Pharma Research & Early Development, pRED</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/radvanyi_laszlo-jpeg_592b7949-65a0-439d-a3c9-11ff36364918.jpeg?sfvrsn=2d8b3acc_40" class="SpeakerFl" alt="Laszlo G. Radvanyi" sf-size="101866" /><b>Uncovering the Role of Non-Coding Genome: A Revolution in Cancer Therapeutics and Human Health</b><br /><i>Laszlo G. Radvanyi, PhD, President & Scientific Director, Ontario Institute for Cancer Research</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/sewell_andrew-png_79fbb954-782f-4bfc-a78c-e8b4d615309f.jpg?sfvrsn=e9d4f237_60" class="SpeakerFl" alt="Andrew Sewell" sf-size="95464" /><b>HLA-Agnostic T Cell Receptor Recognition of Cancer</b><br /><i>Andrew Sewell, PhD, Distinguished Research Professor and Wellcome Trust Senior Investigator, Division of Infection and Immunity, Cardiff University School of Medicine</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/deane_charlotte-jpg_fab7944d-a827-4d08-b4f8-105befa9695f.jpg?sfvrsn=4290d91a_39" class="SpeakerFl" alt="Charlotte M. Deane" sf-size="96278" /><b>Moving the Dial on Computational Antibody Design—Optimising beyond Affinity</b><br /><i>Charlotte M. Deane, PhD, Professor, Structural Bioinformatics, Statistics, University of Oxford; Executive Chair, Engineering and Physical Sciences Research Council (EPSRC)</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/bones_jonathan-jpg_f1de5918-1023-42b1-a043-8c20c818771a.jpg?sfvrsn=6dfd1bb3_38" class="SpeakerFl" alt="Jonathan Bones" sf-size="75256" /><b>Microheterogeneity Assessment of Biopharmaceuticals Using an Orbitrap Tribrid Mass Spectrometer</b><br /><i>Jonathan Bones, PhD, Principal Investigator, Characterisation and Comparability Laboratory, National Institute for Bioprocessing Research and Training (NIBRT), Ireland</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/turbica_isabelle-jpg_e082e39f-82b1-4233-b2c7-768527b0ef7b.jpg?sfvrsn=1433a1d7_6" class="SpeakerFl" alt="Isabelle Turbica" sf-size="126240" /><b>Role of Aggregation in Therapeutic Antibodies Immunogenicity: Initiation of Innate and Specific Immune Responses</b><br /><i>Isabelle Turbica, PhD, Associate Professor, Biotechnology, School of Pharmacy, Paris-Saclay University, France</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/burgess-brown_nicola-jpeg_e34c5ffc-2f9f-4274-93c5-bae0ea9ec2ba.jpeg?sfvrsn=76d31d32_44" class="SpeakerFl" alt="Nicola Burgess-Brown" /><b>Target 2035: The Goal to Develop a Pharmacological Modulator for Every Human Protein</b><br /><i>Nicola Burgess-Brown, PhD, COO and Consultant, Protein Sciences, Structural Genomics Consortium; Visiting Scientist, University College London</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/berrow_nick-jpg_db10f6af-2432-44ea-97e6-3961eb677136.jpg?sfvrsn=c622b273_7" class="SpeakerFl" alt="Nick Berrow" /><b>Optimisation Step 1—Choosing a Suitable Gene Expression System for Your Recombinant Protein Production</b><br /><i>Nick Berrow, PhD, Manager, Protein Expression Core Facility, Institute for Research in Biomedicine IRB Barcelona, Barcelona Institute of Science and Technology (BIST)</i></p><br clear="all" /><p><img src="/images/default-source/speakerphotos/spycher_philipp-jpg_af325c76-054d-4cc3-824e-fc061f01f46c.jpg?sfvrsn=567f10d9_43" class="SpeakerFl" alt="Philipp Spycher" /><b>Novel Dual-Payload ADCs That Show Excellent Biophysical Properties and High Efficacy <i>in Vivo</i></b><br /><i>Philipp Spycher, PhD, CEO, Araris Biotech AG</i></p><br clear="all" /><p><b> </b></p><p><b><i>* As of 17 July. 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