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KEGG DRUG: Iproclozide
<!doctype html> <html><head> <title>KEGG DRUG: Iproclozide</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1743702646"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1743702646"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1743702646" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « 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form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="650"><tr><td width=70><a href="/kegg/drug"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg5.gif"></a></td><td> </td><td><a name="drug:D07338"></a><font class="title5">DRUG: Iproclozide</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_drug.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/entry/" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr5 w1"> <table width="650" class="w2"> <tr><th class="th50 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td50 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">D07338 Drug <br> </span></code></td></tr></table></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td51 defd"><div class="cel">Iproclozide (INN);<br>Iproclozide (TN)</div></td></tr> <tr><th class="th50 deft tal vtop"><span class="nowrap">Formula</span></th> <td class="td50 defd"><div class="cel">C11H15ClN2O2<br> </div></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Exact mass</span></th> <td class="td51 defd"><div class="cel">242.0822<br> </div></td></tr> <tr><th class="th50 deft tal vtop"><span class="nowrap">Mol weight</span></th> <td class="td50 defd"><div class="cel">242.70<br> </div></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Structure</span></th> <td class="td51 defd"><a href="/Fig/drug/D07338.gif"><img name="img0" src="/Fig/drug/D07338.gif" style="max-width:600px" border=0></a><br> <button class="btn" onclick="location.href='/entry/-f+m+D07338';return false;">Mol file</button><button class="btn" onclick="location.href='/entry/-f+k+D07338';return false;">KCF file</button><button class="btn" onclick="location.href='https://www.genome.jp/tools-bin/strsearch_view?ENTRY=D07338&PROGRAM=simcomp&DATABASE=drug';return false;">DB search</button></td></tr> <tr><th class="th50 deft tal vtop"><span class="nowrap">Class</span></th> <td class="td50 defd"><div class="cel"><span class="nowrap">Neuropsychiatric agent<br> <a href="/entry/DG01568">DG01568</a> MAO inhibitor<br> <a href="/entry/DG01519">DG01519</a> Non-selective monoamine oxidase inhibitor<br> </span></div></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Remark</span></th> <td class="td51 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ATC code: </span></td><td><a href="/brite/br08303+D07338">N06AF06</a></td></tr></table></td></tr> <tr><th class="th50 deft tal vtop"><span class="nowrap">Efficacy</span></th> <td class="td50 defd"><div class="cel">Antidepressant, Monoamine oxidase (MAO) inhibitor</div></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Target</span></th> <td class="td51 defd"><div class="cel">MAO [HSA:<a href="/entry/hsa:4128">4128</a> <a href="/entry/hsa:4129">4129</a>] [KO:<a href="/entry/K00274">K00274</a>]</div></td></tr> <tr><th class="th50 rept tal vtop"><span class="nowrap"> Pathway</span></th> <td class="td50 repd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00260+4128+4129">hsa00260</a> </span></td><td>Glycine, serine and threonine metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00330+4128+4129">hsa00330</a> </span></td><td>Arginine and proline metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00340+4128+4129">hsa00340</a> </span></td><td>Histidine metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00350+4128+4129">hsa00350</a> </span></td><td>Tyrosine metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00360+4128+4129">hsa00360</a> </span></td><td>Phenylalanine metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00380+4128+4129">hsa00380</a> </span></td><td>Tryptophan metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa00982+4128+4129">hsa00982</a> </span></td><td>Drug metabolism - cytochrome P450</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa04726+4128+4129">hsa04726</a> </span></td><td>Serotonergic synapse</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/hsa04728+4128+4129">hsa04728</a> </span></td><td>Dopaminergic synapse</td></tr></table></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Interaction</span></th> <td class="td51 defd"><div class="cel"><button class="btn" onclick="location.href='/kegg-bin/ddi_list?drug=D07338';return false;">DDI search</button></div></td></tr> <tr><th class="th50 deft tal vtop"><span class="nowrap">Brite</span></th> <td class="td50 defd"><div class="cel"><span class="nowrap">Anatomical Therapeutic Chemical (ATC) classification [BR:<a href="/brite/br08303+D07338">br08303</a>]<br> N NERVOUS SYSTEM<br> N06 PSYCHOANALEPTICS<br> N06A ANTIDEPRESSANTS<br> N06AF Monoamine oxidase inhibitors, non-selective<br> N06AF06 Iproclozide<br> D07338 Iproclozide (INN)<br> Drug groups [BR:<a href="/brite/br08330+D07338+DG01568">br08330</a>]<br> Neuropsychiatric agent<br> DG01568 MAO inhibitor<br> DG01519 Non-selective monoamine oxidase inhibitor<br> D07338 Iproclozide<br> Target-based classification of drugs [BR:<a href="/brite/br08310+D07338">br08310</a>]<br> Enzymes<br> Oxidoreductases (EC1)<br> Amine oxidases<br> MAO<br> D07338 Iproclozide (INN)<br> </span></div><button class="btn" onclick="location.href='/kegg-bin/search_brite?option=-a&search_string=D07338';return false;">BRITE hierarchy</button></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td51 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">CAS: </span></td><td>3544-35-2</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">PubChem: </span></td><td><a href="https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=51091675">51091675</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">LigandBox: </span></td><td><a href="http://www.mypresto5.com/ligandbox202210/cgi-bin/liginf.cgi?id=D07338&source=KEGG_DRUG">D07338</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">NIKKAJI: </span></td><td><a href="https://jglobal.jst.go.jp/en/redirect?Nikkaji_No=J7.961H">J7.961H</a></td></tr></table></td></tr> <tr><th class="th50 deft tal vmid"><span class="nowrap">LinkDB</span></th> <td class="td50 defd"><button class="btn" onclick="location.href='https://www.genome.jp/dbget-bin/get_linkdb?drug+D07338';return false;">All DBs</button></td></tr> <tr><th class="th51 deft tal vtop"><span class="nowrap">KCF data</span></th> <td class="td51 defd"><button class="btn" id="kcfb1">Show</button><div class="kcfd" id="kcfd1"><br>ATOM 16<br> 1 C8x C 12.7400 -18.6900<br> 2 C8y C 12.7400 -20.0900<br> 3 C8x C 13.9524 -20.7900<br> 4 C8x C 15.1649 -20.0900<br> 5 C8y C 15.1649 -18.6900<br> 6 C8x C 13.9524 -17.9900<br> 7 O2a O 16.4024 -17.9900<br> 8 C1b C 17.6149 -18.6900<br> 9 C5a C 18.8273 -17.9900<br> 10 N1b N 20.0397 -18.6900<br> 11 N1b N 21.2522 -17.9900<br> 12 C1c C 22.4646 -18.6900<br> 13 C1a C 23.6770 -17.9900<br> 14 X Cl 11.5276 -20.7900<br> 15 O5a O 18.8273 -16.5900<br> 16 C1a C 22.4646 -20.0900<br> BOND 16<br> 1 1 2 2<br> 2 2 3 1<br> 3 3 4 2<br> 4 4 5 1<br> 5 5 6 2<br> 6 1 6 1<br> 7 5 7 1<br> 8 7 8 1<br> 9 8 9 1<br> 10 9 10 1<br> 11 10 11 1<br> 12 11 12 1<br> 13 12 13 1<br> 14 2 14 1<br> 15 9 15 2<br> 16 12 16 1<br> </div></td></tr> </table></td></tr></table> <br><span style="font-size:12px"><a href="/entry/dr_ja:D07338">» Japanese version</a> <a href="javascript:history.back();">» Back</a></span><br><br></td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>