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Biologics

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Coverage</span> </li> <li> <h4> <a href="/web/20131103090431/http://www.healio.com/orthopedics/total-joint-reconstruction/news/online/{04a3bc66-6490-45b3-8244-19bcb0098c22}/study-decreased-need-for-joint-surgery-in-ra-patients-may-be-related-to-increased-use-of-biologics"> Study: Decreased need for joint surgery in RA patients may be related to increased use of biologics</a></h4> </li> <li class="meta-info"> October 31, 2013</li> <li class="meta-info"> Researchers from Malm&ouml; University in Sweden found that a decrease in the need for joint surgery among patients with rheumatoid arthritis seen at a...<a href="/web/20131103090431/http://www.healio.com/orthopedics/total-joint-reconstruction/news/online/{04a3bc66-6490-45b3-8244-19bcb0098c22}/study-decreased-need-for-joint-surgery-in-ra-patients-may-be-related-to-increased-use-of-biologics" class="jump-link inline">More <span>&raquo;</span></a></li> </ul> <ul class="content-list"> <li class="kicker"> </li> <li> <h4> <a href="/web/20131103090431/http://www.healio.com/orthopedics/arthroscopy/news/print/orthopedics-today/{99b06ee6-744b-4d98-9cbc-6a428eb36758}/combination-of-subchondral-drilling-with-ha-stem-cells-grew-better-quality-cartilage"> Combination of subchondral drilling with HA, stem cells grew better quality cartilage</a></h4> </li> <li class="meta-info"> Orthopedics Today, October 2013</li> <li class="meta-info"> Arthroscopic subchondral drilling followed by intra-articular injections of hyaluronic acid and peripheral blood stem cells resulted in a higher quality...<a href="/web/20131103090431/http://www.healio.com/orthopedics/arthroscopy/news/print/orthopedics-today/{99b06ee6-744b-4d98-9cbc-6a428eb36758}/combination-of-subchondral-drilling-with-ha-stem-cells-grew-better-quality-cartilage" class="jump-link inline">More <span>&raquo;</span></a></li> </ul> <ul class="content-list"> <li class="kicker"> <span class="dept">Surgical Technique</span> </li> <li> <h4> <a href="/web/20131103090431/http://www.healio.com/orthopedics/shoulder-elbow/news/print/orthopedics-today/{ccb648cb-090d-48bd-9353-a767b9bee4d7}/fresh-osteochondral-allograft-for-shoulder-resurfacing-relieves-pain"> Fresh osteochondral allograft for shoulder resurfacing relieves pain</a></h4> </li> <li class="meta-info"> Orthopedics Today, October 2013<br/><i>Jonathan J. 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class="meta-info"> Bovine thrombin slightly reduced blood loss after total knee arthroplasty in this randomized clinical trial, but researchers noted it was not cost...<a href="/web/20131103090431/http://www.healio.com/orthopedics/knee/news/online/{d51dbcdc-2b21-4112-8e4f-d343c5b9a51a}/researchers-recommend-against-routine-bovine-thrombin-use-to-reduce-blood-loss-in-tka" class="jump-link inline">More <span>&raquo;</span></a></li> </ul> <ul class="content-list"> <li class="kicker"> </li> <li> <h4> <a href="/web/20131103090431/http://www.healio.com/orthopedics/biologics/news/online/{332374cf-3579-4cfc-8bac-29960bca3060}/meta-analysis-fda-approved-intra-articular-ha-injections-effective-for-knee-oa"> Meta-analysis: FDA-approved intra-articular HA injections effective for knee OA</a></h4> </li> <li class="meta-info"> September 17, 2013</li> <li class="meta-info"> Researchers of a recently published meta-analysis have concluded that intra-articular injections of hyaluronic acid for the 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href="/web/20131103090431/http://www.healio.com/orthopedics/biologics/news/online/{44411c64-022b-4650-8b40-2329d1b21b85}/advanced-biologics-relocates-headquarters" class="jump-link inline">More <span>&raquo;</span></a></li> </ul> <ul class="content-list"> <li class="kicker"> <span class="dept">Industry News</span> </li> <li> <h4> <a href="/web/20131103090431/http://www.healio.com/orthopedics/spine/news/online/{81568567-79b9-404f-b9f6-c76a2a6c1d33}/invibio-biomaterial-solutions-releases-enhanced-polymer-for-bone-apposition"> Invibio Biomaterial Solutions releases enhanced polymer for bone apposition</a></h4> </li> <li class="meta-info"> September 12, 2013</li> <li class="meta-info"> Invibio Biomaterial Solutions has released its PEEK-OPTIMA HA Enhanced Polymer.<br/>The enhanced polymer integrates hydroxyapatite into PEEK-OPTIMA Natural...<a href="/web/20131103090431/http://www.healio.com/orthopedics/spine/news/online/{81568567-79b9-404f-b9f6-c76a2a6c1d33}/invibio-biomaterial-solutions-releases-enhanced-polymer-for-bone-apposition" class="jump-link inline">More <span>&raquo;</span></a></li> </ul> <ul class="content-list"> <li class="kicker"> <span class="dept">In the Journals</span> </li> <li> <h4> <a href="/web/20131103090431/http://www.healio.com/orthopedics/spine/news/online/{0effceca-217e-4485-a189-afcaf9d82884}/study-spinal-surgery-with-rhbmp-2-yields-116-rate-of-major-complications"> Study: Spinal surgery with rhBMP-2 yields 11.6% rate of major complications</a></h4> </li> <li class="meta-info"> September 9, 2013</li> <li class="meta-info"> A group of patients who underwent spinal surgery with a dose of recombinant human morphogenetic protein-2 greater than 40 mg had a 11.6% incidence of...<a 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