CINXE.COM

Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L' | CNRS Images

<!DOCTYPE html> <html lang="fr" dir="ltr" prefix="og: https://ogp.me/ns#"> <head> <meta charset="utf-8" /> <meta name="description" content="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;objectif est d&#039;identifier des inhibiteurs de kinases impliqu茅es dans des pathologies humaines, comprendre leurs m茅canismes d&#039;action mol茅culaire et d茅velopper leur 茅tude vers des applications cliniques." /> <link rel="shortlink" href="https://images.cnrs.fr/node/74245" /> <link rel="canonical" href="https://images.cnrs.fr/photo/20070001_1227" /> <link rel="image_src" href="https://images.cnrs.fr/sites/default/files/textimage_store/cache/styles/full_image_copyright/e/ed/ed335597291783e09c76fdc1c662514b79906b9aa83b9107dd2323dbf68ad0d2.jpg" /> <link rel="icon" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/favicon.ico" /> <link rel="icon" sizes="16x16" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/favicon-16x16.png" /> <link rel="icon" sizes="32x32" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/favicon-32x32.png" /> <link rel="icon" sizes="96x96" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/android-icon-96x96.png" /> <link rel="icon" sizes="192x192" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/android-icon-192x192.png" /> <link rel="apple-touch-icon" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-60x60.png" /> <link rel="apple-touch-icon" sizes="72x72" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-72x72.png" /> <link rel="apple-touch-icon" sizes="76x76" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-76x76.png" /> <link rel="apple-touch-icon" sizes="114x114" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-114x114.png" /> <link rel="apple-touch-icon" sizes="120x120" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-120x120.png" /> <link rel="apple-touch-icon" sizes="144x144" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-144x144.png" /> <link rel="apple-touch-icon" sizes="152x152" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-152x152.png" /> <link rel="apple-touch-icon" sizes="180x180" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-180x180.png" /> <link rel="apple-touch-icon-precomposed" sizes="180x180" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/apple-icon-180x180.png" /> <meta property="og:site_name" content="CNRS Images" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://images.cnrs.fr/photo/20070001_1227" /> <meta property="og:title" content="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;" /> <meta property="og:description" content="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;objectif est d&#039;identifier des inhibiteurs de kinases impliqu茅es dans des pathologies humaines, comprendre leurs m茅canismes d&#039;action mol茅culaire et d茅velopper leur 茅tude vers des applications cliniques." /> <meta property="og:image" content="https://images.cnrs.fr/sites/default/files/textimage_store/cache/styles/full_image_copyright/e/ed/ed335597291783e09c76fdc1c662514b79906b9aa83b9107dd2323dbf68ad0d2.jpg" /> <meta property="og:image:url" content="https://images.cnrs.fr/sites/default/files/textimage_store/cache/styles/full_image_copyright/e/ed/ed335597291783e09c76fdc1c662514b79906b9aa83b9107dd2323dbf68ad0d2.jpg" /> <meta property="og:image:secure_url" content="https://images.cnrs.fr/sites/default/files/textimage_store/cache/styles/full_image_copyright/e/ed/ed335597291783e09c76fdc1c662514b79906b9aa83b9107dd2323dbf68ad0d2.jpg" /> <meta property="og:image:type" content="image/jpeg" /> <meta property="og:image:alt" content="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;" /> <meta property="article:author" content="Hubert RAGUET" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:description" content="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;objectif est d&#039;identifier des inhibiteurs de kinases impliqu茅es dans des pathologies humaines, comprendre leurs m茅canismes d&#039;action mol茅culaire et d茅velopper leur 茅tude vers des applications cliniques." /> <meta name="twitter:title" content="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;" /> <meta name="twitter:site" content="cnrsimages" /> <meta name="twitter:site:id" content="602669747" /> <meta name="twitter:dnt" content="on" /> <meta name="twitter:url" content="https://images.cnrs.fr/photo/20070001_1227" /> <meta name="twitter:image" content="https://images.cnrs.fr/sites/default/files/textimage_store/cache/styles/full_image_copyright/e/ed/ed335597291783e09c76fdc1c662514b79906b9aa83b9107dd2323dbf68ad0d2.jpg" /> <meta name="theme-color" content="#ffffff" /> <link rel="manifest" href="https://images.cnrs.fr/themes/custom/cnrs_images/favs/manifest.json" crossorigin="use-credentials" /> <meta name="application-name" content="CNRS Images" /> <meta name="msapplication-config" content="https://images.cnrs.fr/themes/custom/cnrs_images/favs/browserconfig.xml" /> <meta name="msapplication-square150x150logo" content="https://images.cnrs.fr/themes/custom/cnrs_images/favs/ms-icon-150x150.png" /> <meta name="msapplication-square310x310logo" content="https://images.cnrs.fr/themes/custom/cnrs_images/favs/ms-icon-310x310.png" /> <meta name="msapplication-square70x70logo" content="https://images.cnrs.fr/themes/custom/cnrs_images/favs/ms-icon-70x70.png" /> <meta name="msapplication-tilecolor" content="#ffffff" /> <meta name="Generator" content="Drupal 9 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <link rel="alternate" hreflang="en" href="https://images.cnrs.fr/en/photo/20070001_1227" /> <link rel="alternate" hreflang="fr" href="https://images.cnrs.fr/photo/20070001_1227" /> <title>Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039; | CNRS Images</title> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_pBH2wUr_Dzi7fv5KxowaE0mWjbRRbaPJOvzptzqy3kg.css" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_e_5GTlixH3A9hGNRG3-UbMLcvYVYnKPBTvs5lTpCSyU.css" /> <link rel="stylesheet" media="print" href="/sites/default/files/css/css_2kzwaZgA7pkS2JjRz2DbOO3SdeTlfNiiJ6_nLxcUCuM.css" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_LLLdVa9OBSlDbDOvQbmrnCj_gFYD_wZJ2avHUq2UTy8.css" /> </head> <body data-route="entity.node.canonical" class="path-node page-node-type-fiche-photo"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to content </a> <a href="#pieddepage" class="visually-hidden focusable skip-link"> Skip to footer </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <aside> <div class="region region-sidenav"> <div role="dialog" aria-label="Menu principal" id="block-cnrssidenavigation" aria-expanded="false" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-side-navigation"> <div><nav class="sidebar-menu sidebar-menu-main" aria-label="Navigation principale"><button class="menu-toggler">Fermer Menu</button> <a href="/utilisateur" class="account-link">Mon compte</a> <ul class="menu"> <li class="menu-item menu-item--expanded"> <a href="/explorer" title="Explorer nos ressources" data-drupal-link-system-path="landing/2">Explorer</a> <ul class="menu"> <li class="menu-item"> <a href="/explorer" title="Nos m茅dias par grandes th茅matiques" data-drupal-link-system-path="landing/2">Th茅matiques</a> </li> <li class="menu-item"> <a href="/explorer/actualites-scientifiques-en-images" title="Nos m茅dias sur l鈥檃ctualit茅 scientifique" data-drupal-link-system-path="landing/7">Actualit茅s scientifiques</a> </li> <li class="menu-item"> <a href="/explorer/dossiers" title="Nos medias sur les grandes questions" data-drupal-link-system-path="landing/1">Dossiers</a> </li> <li class="menu-item"> <a href="/explorer/dernieres-productions" title="Nos films et reportages photos r茅cents" data-drupal-link-system-path="landing/3">Derni猫res productions</a> </li> <li class="menu-item"> <a href="/dossier/nos-expositions" title="consulter et r茅server une expo" data-drupal-link-system-path="node/85119">Nos expositions</a> </li> <li class="menu-item"> <a href="/explorer/archives" title="Nos archives de photos et films" data-drupal-link-system-path="landing/4">Archives</a> </li> </ul> </li> <li class="menu-item menu-item--expanded"> <a href="/contributeurs-cnrs" title="Tous nos contributeurs" data-drupal-link-system-path="landing/5">Contributeurs</a> <ul class="menu"> <li class="menu-item"> <a href="/contributeurs-cnrs" title="D茅couvrez tous nos contributeurs" data-drupal-link-system-path="landing/5">Nos contributeurs</a> </li> <li class="menu-item"> <a href="/laboratoires" title="Toutes les galeries des labos" data-drupal-link-system-path="laboratoires">Galeries des labos</a> </li> <li class="menu-item"> <a href="/contributeurs" title="Galeries des photographes et r茅alisateurs" data-drupal-link-system-path="contributeurs">Galeries d&#039;auteurs</a> </li> <li class="menu-item"> <a href="/contribution-depot-dimages" title="Pour contribuer" data-drupal-link-system-path="node/85112">Contribution-d茅p么t d鈥檌mages</a> </li> </ul> </li> <li class="menu-item menu-item--expanded"> <a href="#_" title="D茅couvrez notre offre">Notre offre</a> <ul class="menu"> <li class="menu-item"> <a href="/communication-scientifique" title="Ressources pour communiquer" data-drupal-link-system-path="node/90774">Communication scientifique</a> </li> <li class="menu-item"> <a href="/nos-expositions" title="Emprunter nos expositions" data-drupal-link-system-path="node/46483">Pr锚t d&#039;expositions</a> </li> <li class="menu-item"> <a href="/fonds-reserves" title="Acc猫s r茅serv茅s pour recherche et enseignement" data-drupal-link-system-path="node/85111">Fonds r茅serv茅s</a> </li> <li class="menu-item"> <a href="/prestation-documentaire" title="Documentation et recherche documentaire" data-drupal-link-system-path="node/46482">Prestation documentaire</a> </li> <li class="menu-item"> <a href="/subventions-productions-de-films" title="Vous avez un projet de film" data-drupal-link-system-path="node/85110">Subventions-Productions</a> </li> <li class="menu-item"> <a href="/contribution-depot-dimages" title="Pour d茅poser vos images" data-drupal-link-system-path="node/85112">Contribution-d茅p么t d&#039;images</a> </li> <li class="menu-item"> <a href="/nos-conditions-generales" title="Consulter nos conditions" data-drupal-link-system-path="node/90663">Conditions g茅n茅rales</a> </li> <li class="menu-item"> <a href="/nos-tarifs" title="Consulter nos tarifs" data-drupal-link-system-path="node/85109">Tarifs</a> </li> </ul> </li> <li class="menu-item menu-item--expanded"> <a href="/cnrs-images" title="脌 propos de CNRS Images" data-drupal-link-system-path="node/46481">脌 propos</a> <ul class="menu"> <li class="menu-item"> <a href="/le-cnrs" title="Pr茅sentation du CNRS" data-drupal-link-system-path="node/90775">Le CNRS</a> </li> <li class="menu-item"> <a href="/cnrs-images" title="Pr茅sentation de CNRS Images" data-drupal-link-system-path="node/46481">CNRS Images</a> </li> <li class="menu-item"> <a href="/actualites" title="Les actualit茅s de CNRS Images" data-drupal-link-system-path="actualites">Actus de CNRS Images</a> </li> <li class="menu-item"> <a href="/nous-contacter" title="pour nous contacter" data-drupal-link-system-path="node/19">Nous contacter</a> </li> </ul> </li> <li class="menu-item"> <a href="/actualites" title="D茅couvrir les actus de CNRS Images" data-drupal-link-system-path="actualites">Actus de CNRS Images</a> </li> </ul> </nav> <a href="https://lejournal.cnrs.fr/nos-blogs/les-yeux-de-la-science/" target="_blank" title="Les yeux de la science" class="promoted-link"><span>Le blog</span>Les yeux de la science</a><nav class="sidebar-menu sidebar-menu-secondary" aria-label="Navigation secondaire"> <ul class="menu"> <li class="menu-item"> <a href="/nos-conditions-generales" title="Nos conditions g茅n茅rales" data-drupal-link-system-path="node/90663">Conditions g茅n茅rales</a> </li> <li class="menu-item"> <a href="/mentions-legales" title="Mentions l茅gales" data-drupal-link-system-path="node/90915">Mentions l茅gales</a> </li> <li class="menu-item"> <a href="/donnees-personnelles" title="RGPD" data-drupal-link-system-path="node/90916">Donn茅es personnelles</a> </li> <li class="menu-item"> <a href="/credits" title="Cr茅dits" data-drupal-link-system-path="node/91070">Cr茅dits</a> </li> </ul> </nav> <div class="language-switcher-link" aria-label="Changer la langue du site"><ul class="language-switcher-language-url"><li hreflang="en" data-drupal-link-query="{&quot;type&quot;:&quot;fiche_photo&quot;}" data-drupal-link-system-path="node/59253" class="en"><a href="/en/photographe/perez-thierry?type=fiche_photo" class="language-link" aria-label="EN : S茅lectionner la langue Anglais" title="EN : S茅lectionner la langue Anglais" hreflang="en" data-drupal-link-query="{&quot;type&quot;:&quot;fiche_photo&quot;}" data-drupal-link-system-path="node/59253">en</a></li><li hreflang="fr" data-drupal-link-query="{&quot;type&quot;:&quot;fiche_photo&quot;}" data-drupal-link-system-path="node/59253" class="fr"><a href="/photographe/perez-thierry?type=fiche_photo" class="language-link" aria-label="FR : S茅lectionner la langue Fran莽ais" title="FR : S茅lectionner la langue Fran莽ais" aria-current="true" hreflang="fr" data-drupal-link-query="{&quot;type&quot;:&quot;fiche_photo&quot;}" data-drupal-link-system-path="node/59253">fr</a></li></ul></div> </div> </div> </div> </aside> <div class="layout-container"> <div class="region region-message-zone"> <div data-drupal-messages-fallback class="hidden"></div> </div> <header role="banner"> <div class="region region-header"> <div id="block-cnrsmenutoogle" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-menu-toggle"> <button class="hamburger" aria-label="Ouvrir le menu" aria-controls="block-cnrssidenavigation"><i aria-hidden='true' class='burger-icon'>Menu</i><span class='sr-only'>Ouvrir le menu</span></button> </div> <div id="block-marquedusite" class="block block-system block-system-branding-block"> <div class="site-name"> <a href="/" title="CNRS Images : Accueil" title="CNRS Images">CNRS Images</a> </div> </div> <nav role="navigation" aria-labelledby="block-navigationprincipale-menu" id="block-navigationprincipale" class="block block-menu navigation menu--main"> <h2 class="visually-hidden" id="block-navigationprincipale-menu">Navigation principale</h2> <ul class="menu"> <li class="menu-item menu-item--expanded"> <a href="/explorer" title="Explorer nos ressources" data-drupal-link-system-path="landing/2">Explorer</a> <ul class="menu"> <li class="menu-item"> <a href="/explorer" title="Nos m茅dias par grandes th茅matiques" data-drupal-link-system-path="landing/2">Th茅matiques</a> </li> <li class="menu-item"> <a href="/explorer/actualites-scientifiques-en-images" title="Nos m茅dias sur l鈥檃ctualit茅 scientifique" data-drupal-link-system-path="landing/7">Actualit茅s scientifiques</a> </li> <li class="menu-item"> <a href="/explorer/dossiers" title="Nos medias sur les grandes questions" data-drupal-link-system-path="landing/1">Dossiers</a> </li> <li class="menu-item"> <a href="/explorer/dernieres-productions" title="Nos films et reportages photos r茅cents" data-drupal-link-system-path="landing/3">Derni猫res productions</a> </li> <li class="menu-item"> <a href="/dossier/nos-expositions" title="consulter et r茅server une expo" data-drupal-link-system-path="node/85119">Nos expositions</a> </li> <li class="menu-item"> <a href="/explorer/archives" title="Nos archives de photos et films" data-drupal-link-system-path="landing/4">Archives</a> </li> </ul> </li> <li class="menu-item menu-item--expanded"> <a href="/contributeurs-cnrs" title="Tous nos contributeurs" data-drupal-link-system-path="landing/5">Contributeurs</a> <ul class="menu"> <li class="menu-item"> <a href="/contributeurs-cnrs" title="D茅couvrez tous nos contributeurs" data-drupal-link-system-path="landing/5">Nos contributeurs</a> </li> <li class="menu-item"> <a href="/laboratoires" title="Toutes les galeries des labos" data-drupal-link-system-path="laboratoires">Galeries des labos</a> </li> <li class="menu-item"> <a href="/contributeurs" title="Galeries des photographes et r茅alisateurs" data-drupal-link-system-path="contributeurs">Galeries d&#039;auteurs</a> </li> <li class="menu-item"> <a href="/contribution-depot-dimages" title="Pour contribuer" data-drupal-link-system-path="node/85112">Contribution-d茅p么t d鈥檌mages</a> </li> </ul> </li> <li class="menu-item menu-item--expanded"> <a href="#_" title="D茅couvrez notre offre">Notre offre</a> <ul class="menu"> <li class="menu-item"> <a href="/communication-scientifique" title="Ressources pour communiquer" data-drupal-link-system-path="node/90774">Communication scientifique</a> </li> <li class="menu-item"> <a href="/nos-expositions" title="Emprunter nos expositions" data-drupal-link-system-path="node/46483">Pr锚t d&#039;expositions</a> </li> <li class="menu-item"> <a href="/fonds-reserves" title="Acc猫s r茅serv茅s pour recherche et enseignement" data-drupal-link-system-path="node/85111">Fonds r茅serv茅s</a> </li> <li class="menu-item"> <a href="/prestation-documentaire" title="Documentation et recherche documentaire" data-drupal-link-system-path="node/46482">Prestation documentaire</a> </li> <li class="menu-item"> <a href="/subventions-productions-de-films" title="Vous avez un projet de film" data-drupal-link-system-path="node/85110">Subventions-Productions</a> </li> <li class="menu-item"> <a href="/contribution-depot-dimages" title="Pour d茅poser vos images" data-drupal-link-system-path="node/85112">Contribution-d茅p么t d&#039;images</a> </li> <li class="menu-item"> <a href="/nos-conditions-generales" title="Consulter nos conditions" data-drupal-link-system-path="node/90663">Conditions g茅n茅rales</a> </li> <li class="menu-item"> <a href="/nos-tarifs" title="Consulter nos tarifs" data-drupal-link-system-path="node/85109">Tarifs</a> </li> </ul> </li> <li class="menu-item menu-item--expanded"> <a href="/cnrs-images" title="脌 propos de CNRS Images" data-drupal-link-system-path="node/46481">脌 propos</a> <ul class="menu"> <li class="menu-item"> <a href="/le-cnrs" title="Pr茅sentation du CNRS" data-drupal-link-system-path="node/90775">Le CNRS</a> </li> <li class="menu-item"> <a href="/cnrs-images" title="Pr茅sentation de CNRS Images" data-drupal-link-system-path="node/46481">CNRS Images</a> </li> <li class="menu-item"> <a href="/actualites" title="Les actualit茅s de CNRS Images" data-drupal-link-system-path="actualites">Actus de CNRS Images</a> </li> <li class="menu-item"> <a href="/nous-contacter" title="pour nous contacter" data-drupal-link-system-path="node/19">Nous contacter</a> </li> </ul> </li> </ul> </nav> <div id="block-cnrsusermenu" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-user-menu"> <div class="language-switcher-link" aria-label="Changer la langue du site"><ul class="language-switcher-language-url"><li hreflang="en" data-drupal-link-system-path="node/74245" class="en"><a href="/en/photo/20070001_1227" class="language-link" aria-label="EN : S茅lectionner la langue Anglais" title="EN : S茅lectionner la langue Anglais" hreflang="en" data-drupal-link-system-path="node/74245">en</a></li><li hreflang="fr" data-drupal-link-system-path="node/74245" class="fr is-active"><a href="/photo/20070001_1227" class="language-link is-active" aria-label="FR : S茅lectionner la langue Fran莽ais" title="FR : S茅lectionner la langue Fran莽ais" aria-current="true" hreflang="fr" data-drupal-link-system-path="node/74245">fr</a></li></ul></div> <div class="search-link"><a href="/search/input" title="Rechercher" aria-label="Lancer une recherche" aria-controls="cnrs-images-search-suggestions-results" class="use-ajax" data-dialog-type="modal" data-dialog-options="{&quot;dialogClass&quot;:&quot;search-popin&quot;,&quot;closeText&quot;:&quot;Fermer la recherche&quot;,&quot;aria-label&quot;:&quot;Recherche&quot;}" role="button">Recherche</a></div> <div class="account-link anonymous"><a href="/utilisateur" title="Mon compte">Mon compte</a></div> <div class="cart-link"><a href="/cart" class="panier empty" title="Mon panier">Mon panier <span class="cart-items">0</span></a></div> </div> </div> </header> <main role="main" id="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <div class="region region-content"> <div id="block-cnrs-images-content" class="block block-system block-system-main-block"> <div class="display-wrapper view-masonry hidden"><div class="toggle-gallery" tabindex="0"><div class="classic"></div><div class="masonry"></div></div> <span>Affichage</span></div> <article role="article" class="node--type-media node--type-media-fiche node node--type-fiche-photo node--view-mode-full" data-id="74245"> <div class="node__content"> <a href="/reportage-photo/rep000938" class="reportage-link-modale get-popin" hreflang="fr"><i class="icon icon-media-group" aria-hidden="true"></i> Retour au reportage</a><a href="/reportage-photo/rep000938" class="reportage-link" hreflang="fr"><i class="icon icon-media-group" aria-hidden="true"></i> Retour au reportage</a><div class="cart-link"><a href="/cart" class="panier empty" title="Mon panier">Mon panier <span class="cart-items">0</span></a></div> <div class="node__content__media"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-fiche-media-watermark"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <picture> <source srcset="/system/files/styles/full_image_desktop_watermark/private/media/images/2007/01/CNRS_20070001_1227_19144.jpg?itok=sjArZ4ww 1x" media="all and (min-width: 768px)" type="image/jpeg"/> <source srcset="/system/files/styles/full_image_tablet_watermark/private/media/images/2007/01/CNRS_20070001_1227_19144.jpg?itok=30QDq7vM 1x" media="all and (min-width: 480px)" type="image/jpeg"/> <source srcset="/system/files/styles/full_image_mobile_watermark/private/media/images/2007/01/CNRS_20070001_1227_19144.jpg?itok=06OQYb5w 1x" type="image/jpeg"/> <img src="/system/files/styles/full_image_mobile_watermark/private/media/images/2007/01/CNRS_20070001_1227_19144.jpg?itok=06OQYb5w" alt="20070001_1227" /> </picture> </div> <div class="group group--flex info"> <p class="field field--name-field-credits field--type-string-long field--label-hidden field__item">漏 Hubert RAGUET / CNRS Images</p> </div> </article> </div> <button class="fullscreen" aria-label="Afficher la photographie en plein 茅cran : Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;" data-label="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;">Plein 茅cran</button> <div class="share-links" aria-label="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;" aria-modal role="dialog"><button id="share-links-button" aria-controls="share-links-list" aria-label="Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;">Partager</button> <div class="item-list"><ul id="share-links-list"><li><a href="https://www.facebook.com/sharer/sharer.php?u=https%3A//images.cnrs.fr/photo/20070001_1227" class="button_facebook facebook" target="_blank" title="Partager sur facebook" aria-label="facebook : Partager - nouvelle fen锚tre">facebook</a></li><li><a href="http://www.twitter.com/share?url=https%3A//images.cnrs.fr/photo/20070001_1227" class="button_x x" target="_blank" title="Partager sur x" aria-label="x : Partager - nouvelle fen锚tre">x</a></li><li><a href="https://www.linkedin.com/shareArticle?mini=true&amp;url=https%3A//images.cnrs.fr/photo/20070001_1227" class="button_linkedin linkedin" target="_blank" title="Partager sur linkedin" aria-label="linkedin : Partager - nouvelle fen锚tre">linkedin</a></li><li><a href="https://wa.me/?text=https%3A//images.cnrs.fr/photo/20070001_1227" class="button_whatsapp whatsapp" target="_blank" title="Partager sur whatsapp" aria-label="whatsapp : Partager - nouvelle fen锚tre">whatsapp</a></li><li><a href="mailto:?subject=Les%20organismes%20marins%20%28ici%20une%20%C3%A9toile%20de%20mer%20et%20des%20oursins%29%2C%20une%20source%20de%20mol%C3%A9cules%20bioactives.%20L#039; | CNRS Images&amp;body=https://images.cnrs.fr/photo/20070001_1227" class="button_email email" title="Courriel" aria-label="Partager par email">email</a></li><li><a href="#_" class="button_copy copy" title="Copier l&#039;url" aria-label="Copier l&#039;url dans le presse-papier" data-url="https://images.cnrs.fr/photo/20070001_1227" role="button">copy</a></li></ul></div><p class="url-copied">L'url de cette page a bien 茅t茅 copi茅e dans votre presse-papier!</p> <button id="close-share-links-button" aria-controls="close-share-links-list" aria-label="Fermer la fen锚tre de partage" title="Fermer la fen锚tre de partage">Fermer</button> </div> </div> <header class="article-header"> <div class="article-header-left"> <div class="field field--name-field-ref field--type-string field--label-inline"> <h3 class="field__label">R茅f茅rence</h3> <p class="field__item">20070001_1227</p> </div> <h1 class="title">Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L'</h1> <p class="field field--name-field-description field--type-string-long field--label-hidden field__item">Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;objectif est d&#039;identifier des inhibiteurs de kinases impliqu茅es dans des pathologies humaines, comprendre leurs m茅canismes d&#039;action mol茅culaire et d茅velopper leur 茅tude vers des applications cliniques.</p> </div> <div class="article-header-right"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/74245?token=6Vm-wlwQ3sNHRiBjcK7hHGwSRiL_IrhqzPquD5c6jE8&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Les organismes marins (ici une 茅toile de mer et des oursins), une source de mol茅cules bioactives. L&#039;" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1227" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> <div class="link-cgu-wrapper"><a href="#_" class="btn btn-underline link-cgu" aria-describedby="media-cgu">Conditions d'utilisation</a><div role="tooltip" class="cgu cgu-closed" id="media-cgu"> <div class="field field--name-field-media-cgu field--type-text-long field--label-hidden field__item"><p><em>L鈥檜tilisation des m茅dias visibles sur la Plateforme CNRS Images peut 锚tre accord茅e sur demande. Toute reproduction ou repr茅sentation est interdite sans l'autorisation pr茅alable de CNRS Images (sauf pour les ressources sous licence Creative Commons).</em></p> <p><em>Aucune modification d'une image ne peut 锚tre effectu茅e sans l'accord pr茅alable de CNRS Images.</em></p> <p><em>Aucune utilisation 脿 des fins publicitaires ou diffusion 脿 un tiers d'une image ne peut 锚tre effectu茅e sans l'accord pr茅alable de CNRS Images.</em></p> <p><em>Pour plus de pr茅cisions consulter</em> <u><a href="/nos-conditions-generales"><em>Nos conditions g茅n茅rales</em></a></u></p> </div> </div> <div class="media-more-actions"><button class="print-link print-page" title="Imprimer la fiche">Imprimer la fiche</button> </div> </div> </div> </header> <div class="article-content"> <aside class="article-readmore"> <div class="media-authors"><h3>Photographe(s)</h3> <a href="/recherche/contributeur/59212" class="media-author"><img src="/sites/default/files/styles/media_contributor/public/images/contributeurs/2020/12/HRaguet.jpg?h=735f7c84&amp;itok=whvt5GiB" width="100" height="100" alt="Hubert Raguet" loading="lazy" class="image-style-media-contributor" /> <p>Hubert RAGUET</p> </a><a href="/photographe/raguet-hubert" class="small-link" hreflang="fr">Voir sa galerie</a></div> </aside> <div class="article-description"> <div class="article-section section-date-taille"> <div class="section-left"> <div class="field field--name-field-date-production field--type-datetime field--label-above"> <h3 class="field__label">Ann茅e de production</h3> <p class="field__item">2007</p> </div> </div> <div class="section-right"> <div class="field field--label-inline"><h3>Taille maximale</h3> 31.17 x 20.87 cm / 300 dpi</div> </div> </div> <div class="article-section"> <div class="section-left"> <div class="field"><h3>Laboratoire(s)</h3> <div class="field__items"><div class="field__item"><a href="/recherche/laboratoire/56251">UPS2682 - Mol茅cules et cibles th茅rapeutiques</a><a href="http://www.sb-roscoff.fr/UPSMCT/" target="_blank" class="small-link">Site du laboratoire</a></div> </div> </div> </div> </div> <div class="article-section section-institut-delegation"> <div class="section-right"> <div class="field"><h3>D茅l茅gation(s)</h3> <div class="field__items"><div class="field__item"><a href="/delegations/bretagne-et-pays-de-la-loire" hreflang="fr">Bretagne et Pays de la Loire</a></div> </div> </div> </div> </div> </div> </div> <div class="keywords-blocks"><h2>Mots-cl茅s</h2> <div class="item-list"><ul><li><a href="#_" data-facet="/mots_clef/36484">Etoile de mer</a></li><li><a href="#_" data-facet="/mots_clef/40219">Homme</a></li><li><a href="#_" data-facet="/mots_clef/38925">Inhibiteur d&#039;enzyme</a></li><li><a href="#_" data-facet="/mots_clef/37155">M茅dicament</a></li><li><a href="#_" data-facet="/mots_clef/39343">Mol茅cule</a></li><li><a href="#_" data-facet="/mots_clef/38019">Oursin</a></li><li><a href="#_" data-facet="/mots_clef/39506">Pathologie humaine</a></li></ul></div><a href="#_" class="readmore" title="Afficher la suite des mots-clefs">Voir plus <span>Voir moins</span><i class="icon icon-arrow-down" aria-hidden="true"></i> </a><div class="keywords-blocks--actions"><a href="/recherche" class="btn btn--light search-by-keywords" title="Afficher la suite des mots-clefs">Lancer la recherche</a></div> </div> <div class="thematiques-blocks" data-img="https://images.cnrs.fr/sites/default/files/styles/thematique_desktop/public/images/thematiques/2020/12/CNRS_20150001_0291.jpg?itok=qG28oUa9" data-img-mobile="https://images.cnrs.fr/sites/default/files/styles/thematique_mobile/public/images/thematiques/2020/12/CNRS_20150001_0291.jpg?h=97b639d1&amp;itok=hByx17T6"><div class="thematiques-background-overlay-default"></div> <div class="thematiques-background-overlay"></div> <h2>Th茅matiques scientifiques</h2> <div class="item-list"><ul><li><a href="/thematiques/biologie-animale" data-img="https://images.cnrs.fr/sites/default/files/styles/thematique_desktop/public/images/thematiques/2020/12/CNRS_20150001_0291.jpg?itok=qG28oUa9" data-img-mobile="https://images.cnrs.fr/sites/default/files/styles/thematique_mobile/public/images/thematiques/2020/12/CNRS_20150001_0291.jpg?h=97b639d1&amp;itok=hByx17T6" hreflang="fr">Biologie animale</a></li><li><a href="/thematiques/biologie-marine" data-img="https://images.cnrs.fr/sites/default/files/styles/thematique_desktop/public/images/thematiques/2020/12/CNRS_20110001_1419.jpg?itok=2Rs0dCnq" data-img-mobile="https://images.cnrs.fr/sites/default/files/styles/thematique_mobile/public/images/thematiques/2020/12/CNRS_20110001_1419.jpg?h=933d44cc&amp;itok=6ZIDogn7" hreflang="fr">Biologie marine</a></li><li><a href="/thematiques/biologie-moleculaire-et-cellulaire" data-img="https://images.cnrs.fr/sites/default/files/styles/thematique_desktop/public/images/thematiques/2020/12/CNRS_20170103_0010_V2.jpg?itok=tAZxTnqo" data-img-mobile="https://images.cnrs.fr/sites/default/files/styles/thematique_mobile/public/images/thematiques/2020/12/CNRS_20170103_0010_V2.jpg?h=b61b504c&amp;itok=LUqZbqDC" hreflang="fr">Biologie mol茅culaire et cellulaire</a></li><li><a href="/thematiques/pharmacologie" data-img="https://images.cnrs.fr/sites/default/files/styles/thematique_desktop/public/images/thematiques/2020/11/CNRS_20170073_0005.jpg?itok=pscq0ClE" data-img-mobile="https://images.cnrs.fr/sites/default/files/styles/thematique_mobile/public/images/thematiques/2020/11/CNRS_20170073_0005.jpg?h=394a9795&amp;itok=9fcUvIOl" hreflang="fr">Pharmacologie</a></li></ul></div><div></div></div> <div class="media-slider media-slider--jade" data-slide-center="true" data-slide-infinite="true"><h3 class="title">Issues du m锚me reportage : Mol茅cules et cibles th茅rapeutiques</h3> <div class="media-slider__slider"> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="62715"> <div class="article-wrapper"> <a href="/photo/20070001_1220" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/2007/01/CNRS_20070001_1220_27028.jpg?itok=Qp3RImjd" width="538" height="360" alt="20070001_1220" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Criblage de mol茅cules bioactives issues d'organismes marins. L'objectif est d'identifier des inhibit</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/62715?token=JoBKg-e3N8GMlN-iYFH1TkDMgXfZ-QNKD74AZjC8TpM&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Criblage de mol茅cules bioactives issues d&#039;organismes marins. L&#039;objectif est d&#039;identifier des inhibit" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1220" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="39441"> <div class="article-wrapper"> <a href="/photo/20070001_1221" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/2007/01/CNRS_20070001_1221_25526.jpg?itok=LZxAkRDJ" width="538" height="360" alt="20070001_1221" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Criblage de mol茅cules bioactives issues d'organismes marins. L'objectif est d'identifier des inhibit</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/39441?token=75OPjYcLS_b_zGdng5bGDaRlurXsyl2dbiyhdAkBk7s&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Criblage de mol茅cules bioactives issues d&#039;organismes marins. L&#039;objectif est d&#039;identifier des inhibit" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1221" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="77146"> <div class="article-wrapper"> <a href="/photo/20070001_1211" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1211_39737.jpg?itok=t6eGuaHp" width="480" height="360" alt="20070001_1211" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Filament de l'algue brune "Ectocarpus siliculosus" en culture. Cette algue filamenteuse est un mod猫l</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/77146?token=PCtkV25HXAEdlPVZPcJWsyRAvMYjktzoNXZEfVLO_Tc&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Filament de l&#039;algue brune &quot;Ectocarpus siliculosus&quot; en culture. Cette algue filamenteuse est un mod猫l" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1211" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="83483"> <div class="article-wrapper"> <a href="/photo/20070001_1218" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/2007/01/CNRS_20070001_1218_38232.jpg?itok=Y0GH6gdp" width="538" height="360" alt="20070001_1218" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Criblage de mol茅cules bioactives, issues d'organismes marins, par radio marquage. L'objectif est d'i</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/83483?token=NSyH31CYaRuZBypJTymisf8gNJMskyX-niWTycQkSa0&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Criblage de mol茅cules bioactives, issues d&#039;organismes marins, par radio marquage. L&#039;objectif est d&#039;i" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1218" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="66285"> <div class="article-wrapper"> <a href="/photo/20070001_1210" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1210_37935.jpg?itok=mpUL3ezR" width="480" height="360" alt="20070001_1210" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Rel芒chement de spores par un sporophyte de l'algue brune "Ectocarpus siliculosus". Cette algue filam</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/66285?token=IKEULJdNrRBbMQstZ-vr9uSdTpTmUremfB9ELTQfUTM&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Rel芒chement de spores par un sporophyte de l&#039;algue brune &quot;Ectocarpus siliculosus&quot;. Cette algue filam" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1210" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="78878"> <div class="article-wrapper"> <a href="/photo/20070001_1215" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1215_32498.jpg?itok=p34GZlJj" width="481" height="360" alt="20070001_1215" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Un filament de l'algue brune "Ectocarpus siliculosus" est coup茅 avec le bout d'une pipette pasteur p</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/78878?token=Wfr-J6xn7gpAfTZvZ2KOb2_H3XNTReJ2EW9iDeIlW6U&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Un filament de l&#039;algue brune &quot;Ectocarpus siliculosus&quot; est coup茅 avec le bout d&#039;une pipette pasteur p" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1215" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="63966"> <div class="article-wrapper"> <a href="/photo/20070001_1213" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1213_31044.jpg?itok=AubZm0HB" width="385" height="360" alt="20070001_1213" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Filament de l'algue brune "Ectocarpus siliculosus" avec un sporange pluriloculaire. La paroi color茅e</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/63966?token=OPxcigJJF80y8IkAvbberMU7s4zCLKvy7LzcxPCbYtg&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Filament de l&#039;algue brune &quot;Ectocarpus siliculosus&quot; avec un sporange pluriloculaire. La paroi color茅e" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1213" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="76650"> <div class="article-wrapper"> <a href="/photo/20070001_1214" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1214_28589.jpg?itok=NLWoAuOH" width="350" height="360" alt="20070001_1214" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Structure tridimensionnelle de la kinase CDK2/cycline A en pr茅sence d'un inhibiteur (m茅rioline). L'o</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/76650?token=ZhBNmvxR0xHf13mMy2MHOJ_8mHbWbNf_1cpfEyAIVNw&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Structure tridimensionnelle de la kinase CDK2/cycline A en pr茅sence d&#039;un inhibiteur (m茅rioline). L&#039;o" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1214" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="70606"> <div class="article-wrapper"> <a href="/photo/20070001_1216" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1216_25862.jpg?itok=FsjhjW_d" width="638" height="360" alt="20070001_1216" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Filaments de l'algue brune "Ectocarpus siliculosus" portant des sporanges pluriloculaires. Cette alg</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/70606?token=9CeQRwe3-dMeIhG3vEMdZtX44jPCO0g976BECpkRay8&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Filaments de l&#039;algue brune &quot;Ectocarpus siliculosus&quot; portant des sporanges pluriloculaires. Cette alg" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1216" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-jade-slider slide-item no-details" data-id="74750"> <div class="article-wrapper"> <a href="/photo/20070001_1208" class="get-popin track media-modal-link" role="button"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-jade-slider"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser_slider/private/media/images/0000/00/CNRS_20070001_1208_2480.jpg?itok=pAMvfm1-" width="350" height="360" alt="20070001_1208" class="image-style-media-teaser-slider" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Mod猫le mol茅culaire de la structure tridimensionnelle de la kinase CDK5, enzyme pr茅sente dans plusieu</div> </div> </a> <div class="media-teaser-overlay"> <a href="/utilisateur/connexion?destination=/node/74245" class="wishlist-login" title="Me connecter pour ajouter 脿 ma s茅lection"><i class="icon icon--wishlist" aria-hidden="true" title=""></i> <span>Ajouter 脿 ma s茅lection</span> </a><div class="cart-link-wrapper"><a href="/order/add/74750?token=fD_-zSHRLmb9PFmHXT5Bsru9S-XPzYyxAr4Hr9hzKu4&amp;destination=/photo/20070001_1227" aria-label="Ajouter au panier : Photo Mod猫le mol茅culaire de la structure tridimensionnelle de la kinase CDK5, enzyme pr茅sente dans plusieu" class="add-to-cart use-ajax action--add" data-type="image" data-ref="20070001_1208" rel="nofollow" role="button"><i class="icon icon--cart" aria-hidden="true" title=""></i> Ajouter au panier</a></div> </div> </div> </article> </div> </div> <div class="cnrs-secondary-menu cnrs-secondary-menu--tab"> <div class="cnrs-secondary-menu__left"> <div class="cnrs-secondary-menu__items"> <div class="cnrs-secondary-menu_wrapper"> <a href="/photo/20070001_1227#theme" role="tab" aria-current="true" aria-selected aria-controls="pane-theme" id="theme--2" class="is-active" hreflang="fr">Sur la m锚me th茅matique</a> </div> <button class="visually-hidden focusable skip-menu" role="button">Skip to content menu</button> </div> </div> <div class="cnrs-secondary-menu__right"> </div> </div> <div class="media-slider media-slider--two-rows" role="tabpanel" id="pane-theme" aria-labelledby="theme"><div class="media-slider__slider media-slider__slider--first"><div class="slide-row"> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20100001_0173" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2010/01/CNRS_20100001_0173_21816.jpg?itok=O4OI0e_C" width="550" height="367" alt="20100001_0173" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">An茅mones de mer, sp茅cimens adultes de "Nematostella vectensis " collect茅s sur la c么te du Massachuset</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20070001_1222" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2007/01/CNRS_20070001_1222_5971.jpg?itok=3apBmS5O" width="550" height="822" alt="20070001_1222" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Criblage de mol茅cules bioactives issues d'organismes marins. L'objectif est d'identifier des inhibit</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/19860001_0322" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/0000/00/CNRS_19860001_0322_41182.jpg?itok=ZmJWQ1Jk" width="550" height="820" alt="19860001_0322" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Oeuf de dentale (mollusque) se divisant.</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20040001_1004" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2004/01/CNRS_20040001_1004_37093.jpg?itok=yRG9Ie_N" width="550" height="366" alt="20040001_1004" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Loups de M茅diterran茅e "Dicentrarchus labrax". Lign茅es pigment茅e (naturelle) et albinos (obtenue par</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20070001_1218" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2007/01/CNRS_20070001_1218_38232.jpg?itok=47iJKoGj" width="550" height="368" alt="20070001_1218" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Criblage de mol茅cules bioactives, issues d'organismes marins, par radio marquage. L'objectif est d'i</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20130001_2030" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2011/11/CNRS_20130001_2030_2304.jpg?itok=knx3rya9" width="550" height="141" alt="20130001_2030" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">D茅veloppement du squelette d'un corail acropore, "Acropora millepora"</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20170090_0003" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2004/06/CNRS_20170090_0003_54294.jpg?itok=dEzS3mxP" alt="20170090_0003" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Embryon de l'ascidie solitaire "Ciona intestinalis" en microscopie 脿 茅pifluorescence</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20040001_1007" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2004/01/CNRS_20040001_1007_7505.jpg?itok=uoya0UHM" width="550" height="367" alt="20040001_1007" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Loups de M茅diterran茅e "Dicentrarchus labrax". Lign茅es pigment茅e (naturelle) et albinos (obtenue par</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20040001_1005" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2004/01/CNRS_20040001_1005_37281.jpg?itok=rNaNph-L" width="550" height="367" alt="20040001_1005" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Loups de M茅diterran茅e "Dicentrarchus labrax". Lign茅es pigment茅e (naturelle) et albinos (obtenue par</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20180020_0004" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/0000/00/CNRS_20180020_0004_57393.jpg?itok=3lYy4jga" width="550" height="550" alt="20180020_0004" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Oursin juv茅nile observ茅 en microscopie bi-photonique</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/20170090_0004" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/2004/06/CNRS_20170090_0004_54295.jpg?itok=Mt5peIlR" alt="20170090_0004" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Embryon de l'ascidie solitaire "Ciona intestinalis" en microscopie 脿 茅pifluorescence</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> <article role="article" class="node--type-media node--type-media--teaser node--type-media-fiche node node--type-fiche-photo node--view-mode-teaser-light slide-item"> <div class="article-wrapper"> <a href="/photo/19860001_0313" class="get-popin track media-modal-link"> <div class="field field--name-field-media field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-teaser"> <div class="field field--name-field-image-private field--type-image field--label-hidden field__item"> <img loading="lazy" src="/system/files/styles/media_teaser/private/media/images/0000/00/CNRS_19860001_0313_20182.jpg?itok=VFmZtL1E" width="550" height="369" alt="19860001_0313" class="image-style-media-teaser" /> </div> </article> </div> <div class="media-info"> <div class="node-type">Photo</div> <div class="title">Oeuf d'oursin. Rencontre du mat茅riel g茅n茅tique petit et gros. Les noyaux sont color茅s en bleu par un</div> <i class="node-type-icon node-type-icon--fiche_photo" aria-hidden="true"></i> </div> </a> </div> </article> </div> <div class="slide-row"></div> </div> </div> </div> </article> </div> <div id="block-cnrscitation" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-citation"> <div class="citation-header"><h3>CNRS Images,</h3> </div> <p class="citation-text">Nous mettons en images les recherches scientifiques pour contribuer 脿 une meilleure compr茅hension du monde, 茅veiller la curiosit茅 et susciter l'茅merveillement de tous.</p> </div> </div> </div> </main> <footer role="contentinfo"> <a id="pieddepage" tabindex="-1"></a> <div class="region region-footer"> <div id="block-cnrslogos" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-logos"> <img class="citation-marianne" src="/themes/custom/cnrs_images/assets/images/marianne.svg" alt="R茅publique fran莽aise Libert茅 Egalit茅 Fraternit茅" /> <a href="https://cnrs.fr" target="_blank"><img class="citation-logo" src="/themes/custom/cnrs_images/logo.svg" alt="CNRS - Nouvelle fen锚tre" /> </a> </div> <div id="block-cnrsfootermenu" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-footer-menu"> <nav class="footer-menu footer-menu-main" aria-label="Menu principal du pied de page"> <ul class="menu"> <li class="menu-item"> <a href="/actualites" title="Nos Actus : Les actualit茅s de CNRS Images" data-drupal-link-system-path="actualites">Nos Actus</a> </li> <li class="menu-item"> <a href="/cnrs-images" title="Nous connaitre : CNRS Images" data-drupal-link-system-path="node/46481">Nous connaitre</a> </li> <li class="menu-item"> <a href="/prestation-documentaire" title="Notre offre : d茅couvrez nos offres de service" data-drupal-link-system-path="node/46482">Notre offre</a> </li> <li class="menu-item"> <a href="/nos-tarifs" title="Nos tarifs" data-drupal-link-system-path="node/85109">Nos tarifs</a> </li> <li class="menu-item"> <a href="/nous-contacter" title="Nous contacter" data-drupal-link-system-path="node/19">Nous contacter</a> </li> </ul> </nav> <nav class="footer-menu footer-menu-secondary" aria-label="Menu secondaire du pied de page"> <ul class="menu"> <li class="menu-item"> <a href="/nos-conditions-generales" title="Nos conditions g茅n茅rales" data-drupal-link-system-path="node/90663">Conditions g茅n茅rales</a> </li> <li class="menu-item"> <a href="/mentions-legales" title="Mentions l茅gales" data-drupal-link-system-path="node/90915">Mentions l茅gales</a> </li> <li class="menu-item"> <a href="/donnees-personnelles" title="Donn茅es personnelles" data-drupal-link-system-path="node/90916">Donn茅es personnelles</a> </li> <li class="menu-item"> <a href="/credits" title="Cr茅dits" data-drupal-link-system-path="node/91070">Cr茅dits</a> </li> <li class="menu-item"> <a href="/accessibilite" title="Accessibilit茅" data-drupal-link-system-path="node/100896">Accessibilit茅</a> </li> <li> <a href="" class="tarteaucitronOpenPanel" title="Gestion des cookies">Gestion des cookies</a> </li> </ul> </nav> </div> <div id="block-cnrsfootersocial" class="block block-cnrs-images-common block-cnrs-images-common-cnrs-footer-social"> <div class="footer-socials-networks" aria-label="Lien vers les r茅seaux sociaux"><a href="https://www.facebook.com/CNRS.Images" target="_blank" title="Facebook CNRS Images : Nouvelle fen锚tre" class="social social-facebook">Facebook</a><a href="https://twitter.com/CNRSImages" target="_blank" title="X CNRS : Nouvelle fen锚tre" class="social social-twitter">X</a><a href="https://www.linkedin.com/company/cnrs/" target="_blank" title="LinkedIn CNRS : Nouvelle fen锚tre" class="social social-linkedin">LinkedIn</a><a href="https://www.instagram.com/cnrs/" target="_blank" title="Instagram CNRS : Nouvelle fen锚tre" class="social social-instagram">Instagram</a><a href="https://www.youtube.com/@cnrs" target="_blank" title="YouTube CNRS : Nouvelle fen锚tre" class="social social-youtube">YouTube</a></div> </div> </div> </footer> </div> </div> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","scriptPath":null,"pathPrefix":"","currentPath":"node\/74245","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"fr"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"claro\/classy.node,classy\/base,classy\/messages,classy\/node,cnrs_images\/global-styling,cnrs_images_rgpd\/rgpd,cnrs_images_search\/navigation,core\/normalize,core\/picturefill,system\/base","theme":"cnrs_images","theme_token":null},"ajaxTrustedUrl":[],"cnrs":{"tarteaucitron_cdn":"\/modules\/custom\/cnrs_images_rgpd\/js\/tarteaucitronjs\/","link_data_policy":"\/donnees-personnelles","matomo":{"id":"33","":"url","url":"https:\/\/statistiques.cnrs.fr\/","user_role":"Anonyme"},"currentNodeId":"74245"},"search_route_base":"\/recherche","field_group":{"html_element":{"mode":"fiche_media_watermark","context":"view","settings":{"classes":"group group--flex info","id":"","element":"div","show_label":false,"label_element":"h3","label_element_classes":"","attributes":"","effect":"none","speed":"fast","show_empty_fields":false}}},"langcode":"fr","user":{"uid":0,"permissionsHash":"9055bfba993af7fe44583aa602b1b8ad81b07e756e5d908ef15298cc153e0e50"}}</script> <script src="/sites/default/files/js/js_4BAwYStXzUS1AesLONOzJKtBC2KRl_t6JMcgbkhh1cE.js"></script> </body> </html>

Pages: 1 2 3 4 5 6 7 8 9 10