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role="main" class="widthfix"> <h1 class="page-title">Chemistry (Course 5)</h1> <div id="textcontainer" class="page_content"> </div> <div id="coursestextcontainer" class="page_content"> <a name="coursestext"></a><div id="sc_sccoursedescs"> <div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.000[J] Dimensions of Geoengineering</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=1.850J" title="1.850[J]" class="bubblelink code" onclick="return showCourse(this, '1.850J');">1.850[J]</a>, <a href="/search/?P=10.600J" title="10.600[J]" class="bubblelink code" onclick="return showCourse(this, '10.600J');">10.600[J]</a>, <a href="/search/?P=11.388J" title="11.388[J]" class="bubblelink code" onclick="return showCourse(this, '11.388J');">11.388[J]</a>, <a href="/search/?P=12.884J" title="12.884[J]" class="bubblelink code" onclick="return showCourse(this, '12.884J');">12.884[J]</a>, <a href="/search/?P=15.036J" title="15.036[J]" class="bubblelink code" onclick="return showCourse(this, '15.036J');">15.036[J]</a>, <a href="/search/?P=16.645J" title="16.645[J]" class="bubblelink code" onclick="return showCourse(this, '16.645J');">16.645[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Fall; first half of term)<br/> Not offered regularly; consult department</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Familiarizes students with the potential contributions and risks of using geoengineering technologies to control climate damage from global warming caused by greenhouse gas emissions. Discusses geoengineering in relation to other climate change responses: reducing emissions, removing CO2 from the atmosphere, and adapting to the impacts of climate change. Limited to 100.</p> <p class="courseblockinstructors seemore"><span><i>J. Deutch, M. Zuber</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.002[J] Viruses, Pandemics, and Immunity</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=10.380J" title="10.380[J]" class="bubblelink code" onclick="return showCourse(this, '10.380J');">10.380[J]</a>, <a href="/search/?P=HST.438J" title="HST.438[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.438J');">HST.438[J]</a><br/> Subject meets with <a href="/search/?P=5.003J" title="5.003[J]" class="bubblelink code" onclick="return showCourse(this, '5.003J');">5.003[J]</a>, <a href="/search/?P=8.245J" title="8.245[J]" class="bubblelink code" onclick="return showCourse(this, '8.245J');">8.245[J]</a>, <a href="/search/?P=10.382J" title="10.382[J]" class="bubblelink code" onclick="return showCourse(this, '10.382J');">10.382[J]</a>, <a href="/search/?P=HST.439J" title="HST.439[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.439J');">HST.439[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Spring)<br/> Not offered regularly; consult department</span><br/><span class="courseblockhours">2-0-1 units</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=HST.438J" title="HST.438[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.438J');">HST.438[J]</a>. Preference to first-year students; all others should take <a href="/search/?P=HST.439" title="HST.439[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.439');">HST.439[J]</a>.</p> <p class="courseblockinstructors seemore"><span><i>A. Chakraborty</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.003[J] Viruses, Pandemics, and Immunity</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=8.245J" title="8.245[J]" class="bubblelink code" onclick="return showCourse(this, '8.245J');">8.245[J]</a>, <a href="/search/?P=10.382J" title="10.382[J]" class="bubblelink code" onclick="return showCourse(this, '10.382J');">10.382[J]</a>, <a href="/search/?P=HST.439J" title="HST.439[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.439J');">HST.439[J]</a><br/> Subject meets with <a href="/search/?P=5.002J" title="5.002[J]" class="bubblelink code" onclick="return showCourse(this, '5.002J');">5.002[J]</a>, <a href="/search/?P=10.380J" title="10.380[J]" class="bubblelink code" onclick="return showCourse(this, '10.380J');">10.380[J]</a>, <a href="/search/?P=HST.438J" title="HST.438[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.438J');">HST.438[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Spring)<br/> Not offered regularly; consult department</span><br/><span class="courseblockhours">2-0-1 units</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=HST.439J" title="HST.439[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.439J');">HST.439[J]</a>. <a href="/search/?P=HST.438" title="HST.438[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.438');">HST.438[J]</a> intended for first-year students; all others should take <a href="/search/?P=HST.439" title="HST.439[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.439');">HST.439[J]</a>.</p> <p class="courseblockinstructors seemore"><span><i>A. Chakraborty</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.009[J] Ocean Chemistry Change Laboratory (New)</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=12.314J" title="12.314[J]" class="bubblelink code" onclick="return showCourse(this, '12.314J');">12.314[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a> </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: U (Spring; first half of term)</span><br/><span class="courseblockhours">1-3-2 units. Partial Lab</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=12.314J" title="12.314[J]" class="bubblelink code" onclick="return showCourse(this, '12.314J');">12.314[J]</a>. </p> <p class="courseblockinstructors seemore"><span><i>A. Babbin</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.03 Principles of Inorganic Chemistry I</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.12" title="5.12" class="bubblelink code" onclick="return showCourse(this, '5.12');">5.12</a> </span><br/><span class="courseblockterms">U (Spring)</span><br/><span class="courseblockhours">5-0-7 units</span> </p> <p class="courseblockdesc">Presents principles of chemical bonding and molecular structure, and their application to the chemistry of representative elements of the periodic system. </p> <p class="courseblockinstructors seemore"><span><i>D. Suess, R. Gilliard</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.04 Principles of Inorganic Chemistry II</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> </span><br/><span class="courseblockterms">U (Fall)</span><br/><span class="courseblockhours">4-0-8 units</span> </p> <p class="courseblockdesc">Systematic presentation of the chemical applications of group theory. Emphasis on the formal development of the subject and its applications to the physical methods of inorganic chemical compounds. Against the backdrop of electronic structure, the electronic, vibrational, and magnetic properties of transition metal complexes are presented and their investigation by the appropriate spectroscopy described. </p> <p class="courseblockinstructors seemore"><span><i>Y. Surendranath, D. Freedman</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.05 Principles of Inorganic Chemistry III</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a>; <i>Coreq: <a href="/search/?P=5.04" title="5.04" class="bubblelink code" onclick="return showCourse(this, '5.04');">5.04</a></i> </span><br/><span class="courseblockterms">G (Fall; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Principles of main group (s and p block) element chemistry with an emphasis on synthesis, structure, bonding, and reaction mechanisms. </p> <p class="courseblockinstructors seemore"><span><i>C. C. Cummins</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.061 Principles of Organometallic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> </span><br/><span class="courseblockterms">G (Spring; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">A comprehensive treatment of organometallic compounds of the transition metals with emphasis on structure, bonding, synthesis, and mechanism. </p> <p class="courseblockinstructors seemore"><span><i>C. Cummins</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.062 Principles of Bioinorganic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Fall; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Delineates principles that form the basis for understanding how metal ions function in biology. Examples chosen from recent literature on a range of topics, including the global biogeochemical cycles of the elements; choice, uptake and assembly of metal-containing units; structure, function and biosynthesis of complex metallocofactors; electron-transfer and redox chemistry; atom and group transfer chemistry; protein tuning of metal properties; metalloprotein engineering and design; and applications to diagnosis and treatment of disease. </p> <p class="courseblockinstructors seemore"><span><i>D. Suess</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.064 Solid-state Materials Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> </span><br/><span class="courseblockterms">G (Spring; second half of term)</span><br/><span class="courseblockhours">3-0-3 units</span> </p> <p class="courseblockdesc">Fundamentals of materials chemistry with a focus on solid-state materials. Builds upon ideas of band structure from a chemical perspective and progresses to physical properties, including magnetism and conductivity.聽 </p> <p class="courseblockinstructors seemore"><span><i>D. Freedman</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.065 Electrochemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Spring; first half of term)</span><br/><span class="courseblockhours">3-0-3 units</span> </p> <p class="courseblockdesc">Fundamentals of electrochemistry with an emphasis on physical principles, experimental techniques, and select applications. Builds from molecular-level theories of charge transfer reactions and double layer structure and progress to the use of electrochemistry as a method for characterizing redox properties, synthesizing materials, and interconverting electrical and chemical energy.聽Background in organic chemistry required. </p> <p class="courseblockinstructors seemore"><span><i>Y. Surendranath</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.067 Crystal Structure Refinement</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.069" title="5.069" class="bubblelink code" onclick="return showCourse(this, '5.069');">5.069</a> or permission of instructor </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">2-3-1 units</span> </p> <p class="courseblockdesc">Practical aspects of crystal structure determination from data collection strategies to data reduction and basic and advanced refinement problems of organic and inorganic molecules. </p> <p class="courseblockinstructors seemore"><span><i>P. Mueller</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.068 Physical Inorganic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> and <a href="/search/?P=5.04" title="5.04" class="bubblelink code" onclick="return showCourse(this, '5.04');">5.04</a> </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Spring; second half of term)</span><br/><span class="courseblockhours">3-0-3 units</span> </p> <p class="courseblockdesc">Discusses the physical methods used to probe the electronic and geometric structures of inorganic compounds, with additional techniques employed in the characterization of inorganic solids and surfaces. Includes vibrational spectroscopy, solid state and solution magnetochemical methods, Mossbauer spectroscopy, electron paramagnetic resonance spectroscopy, electrochemical methods, and a brief survey of surface techniques. Applications to current research problems in inorganic and solid-state chemistry. </p> <p class="courseblockinstructors seemore"><span><i>M. Dinca</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.069 Crystal Structure Analysis</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> and <a href="/search/?P=5.04" title="5.04" class="bubblelink code" onclick="return showCourse(this, '5.04');">5.04</a> </span><br/><span class="courseblockterms">G (Spring; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Introduction to X-ray crystallography: symmetry in real and reciprocal space, space and Laue groups, geometry of diffraction, structure factors, phase problem, direct and Patterson methods, electron density maps, structure refinement, crystal growth, powder methods, limits of diffraction methods, structure data bases. </p> <p class="courseblockinstructors seemore"><span><i>P. Mueller</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.07[J] Introduction to Biological Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=20.507J" title="20.507[J]" class="bubblelink code" onclick="return showCourse(this, '20.507J');">20.507[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=5.12" title="5.12" class="bubblelink code" onclick="return showCourse(this, '5.12');">5.12</a> </span><br/><span class="courseblockterms">U (Fall)</span><br/><span class="courseblockhours">5-0-7 units. REST</span><br/><span class="courseblockoptional">Credit cannot also be received for <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a></span> </p> <p class="courseblockdesc">Chemical and physical properties of the cell and its building blocks. Structures of proteins and principles of catalysis. The chemistry of organic/inorganic cofactors required for chemical transformations within the cell. Basic principles of metabolism and regulation in pathways, including glycolysis, gluconeogenesis, fatty acid synthesis/degradation, pentose phosphate pathway, Krebs cycle and oxidative phosphorylation, DNA replication, and transcription and translation. </p> <p class="courseblockinstructors seemore"><span><i>B. Pentelute, E. Nolan</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.08[J] Fundamentals of Chemical Biology</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=7.08J" title="7.08[J]" class="bubblelink code" onclick="return showCourse(this, '7.08J');">7.08[J]</a><br/> Subject meets with <a href="/search/?P=7.80" title="7.80" class="bubblelink code" onclick="return showCourse(this, '7.80');">7.80</a></span><br/><span class="courseblockprereq">Prereq: (<a href="/search/?P=7.012|7.013|7.014|7.015|7.016" onclick="return showCourse(this, '7.012|7.013|7.014|7.015|7.016');">Biology (GIR)</a>, <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a>, and (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>)) or permission of instructor </span><br/><span class="courseblockterms">U (Spring)</span><br/><span class="courseblockhours">4-0-8 units</span> </p> <p class="courseblockdesc">Spanning the fields of biology, chemistry, and engineering, this class introduces students to the principles of chemical biology and the application of chemical and physical methods and reagents to the study and manipulation of biological systems. Topics include nucleic acid structure, recognition, and manipulation; protein folding and stability, and proteostasis; bioorthogonal reactions and activity-based protein profiling; chemical genetics and small-molecule inhibitor screening; fluorescent probes for biological analysis and imaging; and unnatural amino acid mutagenesis. The class will also discuss the logic of dynamic post-translational modification reactions with an emphasis on chemical biology approaches for studying complex processes including glycosylation, phosphorylation, and lipidation. Students taking the graduate version are expected to explore the subject in greater depth. </p> <p class="courseblockinstructors seemore"><span><i>B. Imperiali, R. Raines</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.111 Principles of Chemical Science</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Fall, Spring)</span><br/><span class="courseblockhours">5-0-7 units. CHEMISTRY</span><br/><span class="courseblockoptional">Credit cannot also be received for <a href="/search/?P=3.091" title="3.091" class="bubblelink code" onclick="return showCourse(this, '3.091');">3.091</a>, <a href="/search/?P=5.112" title="5.112" class="bubblelink code" onclick="return showCourse(this, '5.112');">5.112</a>, <a href="/search/?P=CC.5111" title="CC.5111" class="bubblelink code" onclick="return showCourse(this, 'CC.5111');">CC.5111</a>, <a href="/search/?P=ES.5111" title="ES.5111" class="bubblelink code" onclick="return showCourse(this, 'ES.5111');">ES.5111</a>, <a href="/search/?P=ES.5112" title="ES.5112" class="bubblelink code" onclick="return showCourse(this, 'ES.5112');">ES.5112</a></span> </p> <p class="courseblockdesc">Introduction to chemistry, with emphasis on basic principles of atomic and molecular electronic structure, thermodynamics, acid-base and redox equilibria, chemical kinetics, and catalysis. Introduction to the chemistry of biological, inorganic, and organic molecules. </p> <p class="courseblockinstructors seemore"><span><i>A. Willard, B. Pentelute, M. Hong, B. McGuire</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.112 Principles of Chemical Science</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Fall)</span><br/><span class="courseblockhours">5-0-7 units. CHEMISTRY</span><br/><span class="courseblockoptional">Credit cannot also be received for <a href="/search/?P=3.091" title="3.091" class="bubblelink code" onclick="return showCourse(this, '3.091');">3.091</a>, <a href="/search/?P=5.111" title="5.111" class="bubblelink code" onclick="return showCourse(this, '5.111');">5.111</a>, <a href="/search/?P=CC.5111" title="CC.5111" class="bubblelink code" onclick="return showCourse(this, 'CC.5111');">CC.5111</a>, <a href="/search/?P=ES.5111" title="ES.5111" class="bubblelink code" onclick="return showCourse(this, 'ES.5111');">ES.5111</a>, <a href="/search/?P=ES.5112" title="ES.5112" class="bubblelink code" onclick="return showCourse(this, 'ES.5112');">ES.5112</a></span> </p> <p class="courseblockdesc">Introduction to chemistry for students who have taken two or more years of high school chemistry or who have earned a score of at least 4 on the ETS Advanced Placement Exam.聽 Emphasis on basic principles of atomic and molecular electronic structure, thermodynamics, acid-base and redox equilibria, chemical kinetics, and catalysis. Applications of basic principles to problems in metal coordination chemistry, organic chemistry, and biological chemistry. </p> <p class="courseblockinstructors seemore"><span><i>S. Ceyer, M. Dinca</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.12 Organic Chemistry I</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a> </span><br/><span class="courseblockterms">U (Fall, Spring)</span><br/><span class="courseblockhours">5-0-7 units. REST</span><br/><span class="courseblockoptional">Credit cannot also be received for <a href="/search/?P=CC.512" title="CC.512" class="bubblelink code" onclick="return showCourse(this, 'CC.512');">CC.512</a></span> </p> <p class="courseblockdesc">Introduction to organic chemistry. Development of basic principles to understand the structure and reactivity of organic molecules. Emphasis on substitution and elimination reactions and chemistry of the carbonyl group. Introduction to the chemistry of aromatic compounds. </p> <p class="courseblockinstructors seemore"><span><i>J. Johnson, A. Wendlandt, R. Danheiser</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.13 Organic Chemistry II</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.12" title="5.12" class="bubblelink code" onclick="return showCourse(this, '5.12');">5.12</a> </span><br/><span class="courseblockterms">U (Fall)</span><br/><span class="courseblockhours">5-0-7 units</span> </p> <p class="courseblockdesc">Focuses on synthesis, structure determination, mechanism, and the relationships between structure and reactivity. Selected topics illustrate the role of organic chemistry in biological systems and in the chemical industry. </p> <p class="courseblockinstructors seemore"><span><i>L. Kiessling</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.24[J] Archaeological Science</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=3.985J" title="3.985[J]" class="bubblelink code" onclick="return showCourse(this, '3.985J');">3.985[J]</a>, <a href="/search/?P=12.011J" title="12.011[J]" class="bubblelink code" onclick="return showCourse(this, '12.011J');">12.011[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a> or <a href="/search/?P=8.01|8.01L|8.011|8.012" onclick="return showCourse(this, '8.01|8.01L|8.011|8.012');">Physics I (GIR)</a> </span><br/><span class="courseblockterms">U (Spring)</span><br/><span class="courseblockhours">3-1-5 units. HASS-S</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=3.985J" title="3.985[J]" class="bubblelink code" onclick="return showCourse(this, '3.985J');">3.985[J]</a>. </p> <p class="courseblockinstructors seemore"><span><i>M. Tarkanian, J. Meanwell</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.301 Chemistry Laboratory Techniques</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a> and permission of instructor </span><br/><span class="courseblockterms">U (IAP)</span><br/><span class="courseblockhours">1-4-1 units</span> </p> <p class="courseblockdesc">Practical training in basic chemistry laboratory techniques. Intended to provide students with the skills necessary to undertake original research projects in chemistry. Limited to first-year students in IAP (application required); open to all students in spring (enrollment by lottery).</p> <p class="courseblockinstructors seemore"><span><i>J. Dolhun,聽P. Venkatesan</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.302 Introduction to Experimental Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: U (IAP; partial term)</span><br/><span class="courseblockhours">0-3-0 units</span> </p> <p class="courseblockdesc">Illustrates fundamental principles of chemical science through practical experience with chemical phenomena. Students explore the theoretical concepts of chemistry through the experiments which informed their discovery, and make chemistry happen with activities that are intellectually stimulating and fun. Preference to first-year students.</p> <p class="courseblockinstructors seemore"><span><i>J. Dolhun, M. Shoulders</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.310 Laboratory Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None. <i>Coreq: <a href="/search/?P=5.12" title="5.12" class="bubblelink code" onclick="return showCourse(this, '5.12');">5.12</a></i> </span><br/><span class="courseblockterms">U (Fall, Spring)</span><br/><span class="courseblockhours">2-7-3 units. Institute LAB</span> </p> <p class="courseblockdesc">Introduces experimental chemistry for students who are not majoring in Course 5. Principles and applications of chemical laboratory techniques, including preparation and analysis of chemical materials, measurement of pH, gas and liquid chromatography, visible-ultraviolet spectrophotometry, infrared spectroscopy, kinetics, data analysis, and elementary synthesis, are described, in addition to experimental design principles. Includes instruction and practice in written and oral communication to multiple audiences. Enrollment limited.</p> <p class="courseblockinstructors seemore"><span><i>Information: P. Venkatesan</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.351 Fundamentals of Spectroscopy</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a> </span><br/><span class="courseblockterms">U (Fall, Spring; partial term)</span><br/><span class="courseblockhours">1-2-1 units. Partial Lab</span> </p> <p class="courseblockdesc">Students carry out an experiment that introduces fundamental principles of the most common types of spectroscopy, including UV-visible absorption and fluorescence, infrared, and nuclear magnetic resonance. Emphasizes principles of how light interacts with matter, a fundamental and hands-on understanding of how spectrometers work, and what can be learned through spectroscopy about prototype molecules and materials. Students record and analyze spectra of small organic molecules, native and denatured proteins, semiconductor quantum dots, and laser crystals. Satisfies 4 units of Institute Laboratory credit. </p> <p class="courseblockinstructors seemore"><span><i>K. Nelson</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.352 Synthesis of Coordination Compounds and Kinetics</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None. <i>Coreq: <a href="/search/?P=5.351" title="5.351" class="bubblelink code" onclick="return showCourse(this, '5.351');">5.351</a></i> </span><br/><span class="courseblockterms">U (Fall, Spring; partial term)</span><br/><span class="courseblockhours">1-2-2 units. Partial Lab</span> </p> <p class="courseblockdesc">Students carry out an experiment that provides an introduction to the synthesis of simple coordination compounds and chemical kinetics. Illustrates cobalt coordination chemistry and its transformations as detected by visible spectroscopy. Students observe isosbestic points in visible spectra, determine the rate and rate law, measure the rate constant at several temperatures, and derive the activation energy for the aquation reaction. Satisfies 5 units of Institute Laboratory credit. </p> <p class="courseblockinstructors seemore"><span><i>Y. Surendranath</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.353 Macromolecular Prodrugs</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None. <i>Coreq: <a href="/search/?P=5.12" title="5.12" class="bubblelink code" onclick="return showCourse(this, '5.12');">5.12</a> and <a href="/search/?P=5.352" title="5.352" class="bubblelink code" onclick="return showCourse(this, '5.352');">5.352</a></i> </span><br/><span class="courseblockterms">U (Fall, Spring; partial term)</span><br/><span class="courseblockhours">1-2-1 units. Partial Lab</span> </p> <p class="courseblockdesc">Students carry out an experiment that builds skills in how to rationally design macromolecules for drug delivery based on fundamental principles of physical organic chemistry. Begins with conjugation of a drug molecule to a polymerizable group through a cleavable linker to generate a prodrug monomer. Continues with polymerization of monomer to produce macromolecular (i.e., polymer) prodrug; monomer and polymer prodrugs are fully characterized. Rate of drug release is measured and correlated to the size of the macromolecule as well as the structure of the cleavable linker. Satisfies 4 units of Institute Laboratory credit. </p> <p class="courseblockinstructors seemore"><span><i>J. Johnson</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.361 Recombinant DNA Technology</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) and (<a href="/search/?P=5.310" title="5.310" class="bubblelink code" onclick="return showCourse(this, '5.310');">5.310</a> or <a href="/search/?P=5.352" title="5.352" class="bubblelink code" onclick="return showCourse(this, '5.352');">5.352</a>) </span><br/><span class="courseblockterms">U (Spring; partial term)</span><br/><span class="courseblockhours">1-2-1 units</span> </p> <p class="courseblockdesc">Students explore the biochemical basis for the efficacy of a blockbuster drug: Gleevec, which is used to treat chronic myelogenous leukemia. Its target, Abl kinase, is produced in E. coli by recombinant DNA technology, purified using affinity chromatography, and analyzed with polyacrylamide gel electrophoresis, UV-vis spectroscopy, and a colorimetric assay. Natural mutations found in Gleevec-resistant cancer patients are introduced into the ABL1 proto-oncogene with PCR-based mutagenesis and analyzed by agarose gel electrophoresis. </p> <p class="courseblockinstructors seemore"><span><i>R. Raines</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.362 Cancer Drug Efficacy</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) and (<a href="/search/?P=5.310" title="5.310" class="bubblelink code" onclick="return showCourse(this, '5.310');">5.310</a> or <a href="/search/?P=5.352" title="5.352" class="bubblelink code" onclick="return showCourse(this, '5.352');">5.352</a>); <i>Coreq: <a href="/search/?P=5.361" title="5.361" class="bubblelink code" onclick="return showCourse(this, '5.361');">5.361</a></i> </span><br/><span class="courseblockterms">U (Spring; partial term)</span><br/><span class="courseblockhours">1-2-2 units</span> </p> <p class="courseblockdesc">Students probe the structural basis for the development of resistance to Gleevec by cancer patients. LC-MS is used to quantify the effect of Gleevec on catalysis by wild-type Abl kinase and a Gleevec-resistant variant (Module 4). Other potential drugs are tested as inhibitors of the Abl variant. Molecular graphics software is used to understand catalysis by Abl kinase, its inhibition by Gleevec, and the basis for drug resistance. </p> <p class="courseblockinstructors seemore"><span><i>R. Raines</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.363 Organic Structure Determination</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.12" title="5.12" class="bubblelink code" onclick="return showCourse(this, '5.12');">5.12</a>; <i>Coreq: <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a></i> </span><br/><span class="courseblockterms">U (Fall; partial term)</span><br/><span class="courseblockhours">1-2-1 units. Partial Lab</span> </p> <p class="courseblockdesc">Introduces modern methods for the elucidation of the structure of organic compounds. Students carry out transition metal-catalyzed coupling reactions, based on chemistry developed in the Buchwald laboratory, using reactants of unknown structure. Students also perform full spectroscopic characterization - by proton and carbon NMR, IR, and mass spectrometry of the reactants - and carry out coupling products in order to identify the structures of each compound. Other techniques include transfer and manipulation of organic and organometallic reagents and compounds, separation by extraction, and purification by column chromatography. Satisfies 4 units of Institute Laboratory credit. </p> <p class="courseblockinstructors seemore"><span><i>S. Buchwald</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.371 Continuous Flow Chemistry: Sustainable Conversion of Reclaimed Vegetable Oil into Biodiesel</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a> and <a href="/search/?P=5.363" title="5.363" class="bubblelink code" onclick="return showCourse(this, '5.363');">5.363</a> </span><br/><span class="courseblockterms">U (Spring; partial term)</span><br/><span class="courseblockhours">1-2-1 units</span> </p> <p class="courseblockdesc">Presents the theoretical and practical fundamentals of continuous flow synthesis, wherein pumps, tubes, and connectors are used to conduct chemical reactions instead of flasks, beakers, etc. Focuses on a catalytic reaction that converts natural vegetable oil into biodiesel that can be used in a variety of combustion engines. Provides instruction in several important organic chemistry experimental techniques, including purification by extraction, rotary evaporation, acid-base titration, gas chromatography (GC), and <sup>1</sup>H NMR. </p> <p class="courseblockinstructors seemore"><span><i>T. Jamison</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.372 Chemistry of Renewable Energy</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> and <a href="/search/?P=5.352" title="5.352" class="bubblelink code" onclick="return showCourse(this, '5.352');">5.352</a> </span><br/><span class="courseblockterms">U (Fall; partial term)</span><br/><span class="courseblockhours">1-2-1 units</span> </p> <p class="courseblockdesc">Introduces the electrochemical processes that underlie renewable energy storage and recovery. Students investigate charge transfer reactions at electrode surfaces that are critical to the operation of advanced batteries, fuel cells, and electrolyzers. Develops basic theory behind inner- and outer-sphere charge transfer reactions at interfaces and applies this theory to construct mechanistic models for important energy conversion reactions including the reduction of O<sub>2</sub> to water and the reduction of protons to H<sub>2</sub>. Students will also synthesize new catalytic materials for these reactions and investigate their relative performance. </p> <p class="courseblockinstructors seemore"><span><i>Y. Surendranath</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.373 Synthesis of Boron Heterocycles</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> and <a href="/search/?P=5.363" title="5.363" class="bubblelink code" onclick="return showCourse(this, '5.363');">5.363</a> </span><br/><span class="courseblockterms">U (Fall; partial term)</span><br/><span class="courseblockhours">1-2-1 units</span> </p> <p class="courseblockdesc">Experimental module focused on the synthesis and characterization of boron heterocycles, which are used as chemical synthons for metal complexes, small-molecule activation (e.g., carbon dioxide), catalysis mediators, components of optoelectronic materials, monomers for polymeric systems, and molecular building blocks for photochemistry. Covers techniques such as glovebox and Schlenk line methods for synthesis in the absence of oxygen and water; ligand effects, filtration, reaction mixture concentration, and recrystallization under an inert atmosphere. Characterization methods include proton and boron NMR spectroscopy, UV-Vis spectroscopy, and fluorescence measurements. </p> <p class="courseblockinstructors seemore"><span><i>R. Gilliard</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.381 Quantum Dots</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.353" title="5.353" class="bubblelink code" onclick="return showCourse(this, '5.353');">5.353</a> and <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a> </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: U (Spring; partial term)</span><br/><span class="courseblockhours">1-2-1 units</span> </p> <p class="courseblockdesc">Covers synthesis of a discrete size series of quantum dots, followed by synthesis of a single size of core/shell quantum dots utilizing air-free Schlenk manipulation of precursors. Uses characterization by absorption and fluorescence spectroscopies to rationalize the compositional/size dependence of the shell on the electronic structure of the quantum dots. Students acquire time traces of the fluorescence of single core and core/shell quantum dots using single molecule spectroscopic tools. The fluorescence on/off blinking distribution observed will be fit to a standard model. Students use Matlab for computational modeling of the electron and hole wavefunction in core and core/shell quantum dots. Analyzes several commercial applications of quantum dot technologies. </p> <p class="courseblockinstructors seemore"><span><i>M. Bawendi</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.382 Time- and Frequency-resolved Spectroscopy of Photosynthesis</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a> and (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>); <i>Coreq: <a href="/search/?P=5.361" title="5.361" class="bubblelink code" onclick="return showCourse(this, '5.361');">5.361</a></i> </span><br/><span class="courseblockterms">U (Spring; partial term)</span><br/><span class="courseblockhours">1-2-2 units</span> </p> <p class="courseblockdesc">Uses time- and frequency-resolved fluorescence measurements to investigate photosynthetic light harvesting and energy transfer. </p> <p class="courseblockinstructors seemore"><span><i>G. Schlau-Cohen</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.383 Fast-flow Peptide and Protein Synthesis</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.363" title="5.363" class="bubblelink code" onclick="return showCourse(this, '5.363');">5.363</a> and (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: U (Spring; partial term)</span><br/><span class="courseblockhours">1-2-1 units</span> </p> <p class="courseblockdesc">Develops understanding of both the theory and practice of fundamental techniques in biological chemistry, including chemical reactivity (amide-bond formation, solid phase synthesis, disulfide bond formation, and protecting group chemistry); separation science for purification and analysis, such as preparative HPLC and MALDI-TOF MS; and protein structure-function relationships (protein folding and binding). Periodically, guest lecturers from the local biotech research community will describe practical applications in industry. </p> <p class="courseblockinstructors seemore"><span><i>B. Pentelute</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.39 Research and Communication in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: An approved research experience and permission of instructor </span><br/><span class="courseblockterms">U (Spring)</span><br/><span class="courseblockhours">2-12-6 units</span> </p> <p class="courseblockdesc">Independent research under the direction of a member of the Chemistry Department faculty. Allows students with a strong interest in independent research to fulfill 聽part of the laboratory requirement for the Chemistry Department Program in the context of a research laboratory at MIT. The research must be conducted on the MIT campus and be a continuation of a previous 12-unit UROP project or full-time work over the summer. Instruction and practice in written and oral communication is provided, culminating in a poster presentation of the work at the annual departmental UROP symposium and a research publication-style writeup of the results.聽 Permission of the faculty research advisor and the Chemistry Education Office must be obtained in advance. </p> <p class="courseblockinstructors seemore"><span><i>A. Radosevich</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.43 Advanced Organic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a> </span><br/><span class="courseblockterms">U (Spring)</span><br/><span class="courseblockhours">4-0-8 units</span> </p> <p class="courseblockdesc">Reaction mechanisms in organic chemistry: methods of investigation, relation of structure to reactivity, and reactive intermediates. Photochemistry and organometallic chemistry, with an emphasis on fundamental reactivity, mechanistic studies, and applications in organic chemistry. </p> <p class="courseblockinstructors seemore"><span><i>T. Swager</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.44 Organometallic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.061" title="5.061" class="bubblelink code" onclick="return showCourse(this, '5.061');">5.061</a>, <a href="/search/?P=5.43" title="5.43" class="bubblelink code" onclick="return showCourse(this, '5.43');">5.43</a>, <a href="/search/?P=5.47" title="5.47" class="bubblelink code" onclick="return showCourse(this, '5.47');">5.47</a>, or permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Fall; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Examination of the most important transformations of organotransition-metal species. Emphasizes basic mechanisms of their reactions, structure-reactivity relationships, and applications in synthesis. </p> <p class="courseblockinstructors seemore"><span><i>A. Wendlandt</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.45 Heterocyclic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.511" title="5.511" class="bubblelink code" onclick="return showCourse(this, '5.511');">5.511</a> and <a href="/search/?P=5.53" title="5.53" class="bubblelink code" onclick="return showCourse(this, '5.53');">5.53</a> </span><br/><span class="courseblockterms">G (Spring; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Provides an introduction to the chemistry of heterocyclic compounds. Surveys synthesis and reactivity of the major classes of heterocyclic organic compounds. Discusses the importance of these molecules in the pharmaceutical and other industries. </p> <p class="courseblockinstructors seemore"><span><i>S. Buchwald</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.46 NMR Spectroscopy and Organic Structure Determination</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a> </span><br/><span class="courseblockterms">G (Spring; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Applications of multinuclear NMR spectroscopy to the study of organic compounds. </p> <p class="courseblockinstructors seemore"><span><i>W. Massefski</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.47 Tutorial in Organic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.43" title="5.43" class="bubblelink code" onclick="return showCourse(this, '5.43');">5.43</a> and permission of instructor </span><br/><span class="courseblockterms">G (Fall; partial term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Systematic review of fundamental concepts concerned with the structure and transformations of organic molecules. Problem-solving workshop format. The program is intended primarily for first-year graduate students with a strong interest in organic chemistry. Meets during the month of September. </p> <p class="courseblockinstructors seemore"><span><i>S. Buchwald, T. Swager, R. Danheiser,聽J. Johnson,聽M. Movassaghi,聽A. Wendlandt</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.48[J] Protein Folding in Health and Disease</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=7.88J" title="7.88[J]" class="bubblelink code" onclick="return showCourse(this, '7.88J');">7.88[J]</a></span><br/><span class="courseblockprereq">Prereq: (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) and permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Spring; first half of term)</span><br/><span class="courseblockhours">3-0-3 units</span> </p> <p class="courseblockdesc">Focuses on understanding the chemical聽and biological mechanisms of protein folding, misfolding, aggregation, and quality control. Topics covered include: molecular mechanisms of protein folding; experimental and computational strategies to study protein folding; how cells fold and quality control proteins; protein misfolding and aggregation; proteostasis and human disease; strategies to address protein folding failures in disease; and protein folding in biotechnology development. Provides state-of-the-art understanding of the field, fosters ability to critically assess and use the literature, and empowers students to study and address protein folding issues in their research and beyond. </p> <p class="courseblockinstructors seemore"><span><i>M. Shoulders</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.49 Chemical Microbiology</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) and permission of instructor </span><br/><span class="courseblockterms">G (Spring; second half of term)</span><br/><span class="courseblockhours">3-0-3 units</span> </p> <p class="courseblockdesc">Focuses on molecular understanding of fundamental processes central to microbial physiology and infectious disease. Topics covered vary and may include (i) secondary metabolite biosynthesis and function, (ii) small molecule mediators of microbe-microbe and microbe-host interactions, (iii) membrane assembly, (iv) metal homeostasis and regulation, (v) antibiotics and antibiotic resistance, (vi) chemistry of the microbiome, and (vii) molecular basis of host-pathogen interactions. Integrates experimental approaches and primary literature. </p> <p class="courseblockinstructors seemore"><span><i>L. Nolan</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.511 Synthetic Organic Chemistry I</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.43" title="5.43" class="bubblelink code" onclick="return showCourse(this, '5.43');">5.43</a> and permission of instructor </span><br/><span class="courseblockterms">G (Fall; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Presents and discusses important topics in modern synthetic organic chemistry, with the objective of developing problem-solving skills for the design of synthetic routes to complex molecules. </p> <p class="courseblockinstructors seemore"><span><i>M. Movassaghi</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.512 Synthetic Organic Chemistry II</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.511" title="5.511" class="bubblelink code" onclick="return showCourse(this, '5.511');">5.511</a> </span><br/><span class="courseblockterms">G (Spring; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">General methods and strategies for the synthesis of complex organic compounds. </p> <p class="courseblockinstructors seemore"><span><i>M. Movassaghi</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.52 Tutorial in Chemical Biology</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">2-2-8 units</span> </p> <p class="courseblockdesc">Provides an overview of the core principles of chemistry that underlie biological systems. Students explore research topics and methods in chemical biology by participating in laboratory rotations, then present on experiments performed during each rotation. Intended for first-year graduate students with a strong interest in chemical biology. </p> <p class="courseblockinstructors seemore"><span><i>R. Raines</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.53 Molecular Structure and Reactivity</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.43" title="5.43" class="bubblelink code" onclick="return showCourse(this, '5.43');">5.43</a>, <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a>, and <a href="/search/?P=5.602" title="5.602" class="bubblelink code" onclick="return showCourse(this, '5.602');">5.602</a> </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Reaction mechanisms in organic chemistry: methods of investigation, relation of structure to reactivity, and reactive intermediates. </p> <p class="courseblockinstructors seemore"><span><i>A. Radosevich, M. Elkin</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.54[J] Advances in Chemical Biology</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=7.540J" title="7.540[J]" class="bubblelink code" onclick="return showCourse(this, '7.540J');">7.540[J]</a>, <a href="/search/?P=20.554J" title="20.554[J]" class="bubblelink code" onclick="return showCourse(this, '20.554J');">20.554[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a>, <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a>, <a href="/search/?P=7.06" title="7.06" class="bubblelink code" onclick="return showCourse(this, '7.06');">7.06</a>, and permission of instructor </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Introduction to current research at the interface of chemistry, biology, and bioengineering. Topics include imaging of biological processes, metabolic pathway engineering, protein engineering, mechanisms of DNA damage, RNA structure and function, macromolecular machines, protein misfolding and disease, metabolomics, and methods for analyzing signaling network dynamics. Lectures are interspersed with class discussions and student presentations based on current literature. </p> <p class="courseblockinstructors seemore"><span><i>L. Kiessling, M. Shoulders</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.55 NMR Spectroscopy and Biochemical Structure Determination</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> and <a href="/search/?P=5.08" title="5.08[J]" class="bubblelink code" onclick="return showCourse(this, '5.08');">5.08[J]</a>) or permission of instructor </span><br/><span class="courseblockterms">G (Spring; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Practical nuclear magnetic resonance (NMR) spectroscopy applied to problems in biochemistry and chemical biology. </p> <p class="courseblockinstructors seemore"><span><i>W. Massefski</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.56 Molecular Structure and Reactivity II</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.53" title="5.53" class="bubblelink code" onclick="return showCourse(this, '5.53');">5.53</a> or permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Spring; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Application of physical principles and methods to contemporary problems of interest in organic and polymer chemistry. </p> <p class="courseblockinstructors seemore"><span><i>J. Johnson</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.561 Chemistry in Industry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a>, <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a>, and (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) </span><br/><span class="courseblockterms">G (Spring)<br/> Not offered regularly; consult department</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Examination of recent advances in organic, biological, and inorganic and physical chemical research in industry. Taught in seminar format with participation by scientists from industrial research laboratories. </p> <p class="courseblockinstructors seemore"><span><i>R. L. Danheiser</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.601 Thermodynamics I</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=18.02|18.02A|18.022|18.024" onclick="return showCourse(this, '18.02|18.02A|18.022|18.024');">Calculus II (GIR)</a> and <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a> </span><br/><span class="courseblockterms">U (Fall, Spring; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Basic thermodynamics: state of a system, state variables. Work, heat, first law of thermodynamics, thermochemistry. Second and third law of thermodynamics: entropy and free energy, including the molecular basis for these thermodynamic functions. Equilibrium properties of macroscopic systems. Special attention to thermodynamics related to global energy issues and biological systems. Combination of <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a> and <a href="/search/?P=5.602" title="5.602" class="bubblelink code" onclick="return showCourse(this, '5.602');">5.602</a> counts as a REST subject. </p> <p class="courseblockinstructors seemore"><span><i>S. Peng, K. Nelson</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.602 Thermodynamics II and Kinetics</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a> </span><br/><span class="courseblockterms">U (Fall, Spring; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Free energy and chemical potential. Phase equilibrium and properties of solutions. Chemical equilibrium of reactions. Rates of chemical reactions. Special attention to thermodynamics related to global energy issues and biological systems. Combination of <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a> and <a href="/search/?P=5.602" title="5.602" class="bubblelink code" onclick="return showCourse(this, '5.602');">5.602</a> counts as a REST subject. </p> <p class="courseblockinstructors seemore"><span><i>Consult B. McGuire</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.611 Introduction to Spectroscopy</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=18.02|18.02A|18.022|18.024" onclick="return showCourse(this, '18.02|18.02A|18.022|18.024');">Calculus II (GIR)</a>, <a href="/search/?P=3.091|5.111|5.112" onclick="return showCourse(this, '3.091|5.111|5.112');">Chemistry (GIR)</a>, and <a href="/search/?P=8.02|8.021|8.022" onclick="return showCourse(this, '8.02|8.021|8.022');">Physics II (GIR)</a> </span><br/><span class="courseblockterms">U (Fall; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Introductory quantum chemistry; particles and waves; wave mechanics; harmonic oscillator; applications to IR, Microwave and NMR spectroscopy. Combination of <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a> and <a href="/search/?P=5.612" title="5.612" class="bubblelink code" onclick="return showCourse(this, '5.612');">5.612</a> counts as a REST subject. </p> <p class="courseblockinstructors seemore"><span><i>M. Hong</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.612 Electronic Structure of Molecules</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a> </span><br/><span class="courseblockterms">U (Fall; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Introductory electronic structure; atomic structure and the Periodic Table; valence and molecular orbital theory; molecular structure, and photochemistry. Combination of <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a> and <a href="/search/?P=5.612" title="5.612" class="bubblelink code" onclick="return showCourse(this, '5.612');">5.612</a> counts as a REST subject. </p> <p class="courseblockinstructors seemore"><span><i>R. Griffin</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.62 Physical Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a>, <a href="/search/?P=5.602" title="5.602" class="bubblelink code" onclick="return showCourse(this, '5.602');">5.602</a>, <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a>, and <a href="/search/?P=5.612" title="5.612" class="bubblelink code" onclick="return showCourse(this, '5.612');">5.612</a> </span><br/><span class="courseblockterms">U (Spring)</span><br/><span class="courseblockhours">4-0-8 units</span> </p> <p class="courseblockdesc">Elementary statistical mechanics; transport properties; kinetic theory; solid state; reaction rate theory; and chemical reaction dynamics. </p> <p class="courseblockinstructors seemore"><span><i>S. Ceyer, A. Willard</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.64[J] Advances in Interdisciplinary Science in Human Health and Disease</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=HST.539J" title="HST.539[J]" class="bubblelink code" onclick="return showCourse(this, 'HST.539J');">HST.539[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=5.13" title="5.13" class="bubblelink code" onclick="return showCourse(this, '5.13');">5.13</a>, <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a>, <a href="/search/?P=5.602" title="5.602" class="bubblelink code" onclick="return showCourse(this, '5.602');">5.602</a>, and (<a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a>) </span><br/><span class="courseblockterms">G (Spring)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Introduces major principles, concepts, and clinical applications of biophysics, biophysical chemistry, and systems biology. Emphasizes biological macromolecular interactions, biochemical reaction dynamics, and genomics. Discusses current technological frontiers and areas of active research at the interface of basic and clinical science. Provides integrated, interdisciplinary training and core experimental and computational methods in molecular biochemistry and genomics. </p> <p class="courseblockinstructors seemore"><span><i>A. Shalek, X. Wang</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.68[J] Kinetics of Chemical Reactions</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=10.652J" title="10.652[J]" class="bubblelink code" onclick="return showCourse(this, '10.652J');">10.652[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=5.62" title="5.62" class="bubblelink code" onclick="return showCourse(this, '5.62');">5.62</a>, <a href="/search/?P=10.37" title="10.37" class="bubblelink code" onclick="return showCourse(this, '10.37');">10.37</a>, or <a href="/search/?P=10.65" title="10.65" class="bubblelink code" onclick="return showCourse(this, '10.65');">10.65</a> </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Fall)</span><br/><span class="courseblockhours">3-0-6 units</span> </p> <p class="courseblockdesc">Experimental and theoretical aspects of chemical reaction kinetics, including transition-state theories, molecular beam scattering, classical techniques, quantum and statistical mechanical estimation of rate constants, pressure-dependence and chemical activation, modeling complex reacting mixtures, and uncertainty/ sensitivity analyses. Reactions in the gas phase, liquid phase, and on surfaces are discussed with examples drawn from atmospheric, combustion, industrial, catalytic, and biological chemistry. </p> <p class="courseblockinstructors seemore"><span><i>W. H. Green</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.697[J] Computational Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=10.437J" title="10.437[J]" class="bubblelink code" onclick="return showCourse(this, '10.437J');">10.437[J]</a><br/> Subject meets with <a href="/search/?P=5.698J" title="5.698[J]" class="bubblelink code" onclick="return showCourse(this, '5.698J');">5.698[J]</a>, <a href="/search/?P=10.637J" title="10.637[J]" class="bubblelink code" onclick="return showCourse(this, '10.637J');">10.637[J]</a></span><br/><span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: U (Fall)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=10.437J" title="10.437[J]" class="bubblelink code" onclick="return showCourse(this, '10.437J');">10.437[J]</a>. Limited to 35; no listeners.</p> <p class="courseblockinstructors seemore"><span><i>H. J. Kulik</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.698[J] Computational Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=10.637J" title="10.637[J]" class="bubblelink code" onclick="return showCourse(this, '10.637J');">10.637[J]</a><br/> Subject meets with <a href="/search/?P=5.697J" title="5.697[J]" class="bubblelink code" onclick="return showCourse(this, '5.697J');">5.697[J]</a>, <a href="/search/?P=10.437J" title="10.437[J]" class="bubblelink code" onclick="return showCourse(this, '10.437J');">10.437[J]</a></span><br/><span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Fall)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=10.637J" title="10.637[J]" class="bubblelink code" onclick="return showCourse(this, '10.637J');">10.637[J]</a>. Limited to 35; no listeners.</p> <p class="courseblockinstructors seemore"><span><i>H. J. Kulik</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.70[J] Statistical Thermodynamics</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=10.546J" title="10.546[J]" class="bubblelink code" onclick="return showCourse(this, '10.546J');">10.546[J]</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=5.601" title="5.601" class="bubblelink code" onclick="return showCourse(this, '5.601');">5.601</a> or permission of instructor </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Develops classical equilibrium statistical mechanical concepts for application to chemical physics problems. Basic concepts of ensemble theory formulated on the basis of thermodynamic fluctuations. Examples of applications include Ising models, lattice models of binding, ionic and non-ionic solutions, liquid theory, polymer and protein conformations, phase transition, and pattern formation. Introduces computational techniques with examples of liquid and polymer simulations. </p> <p class="courseblockinstructors seemore"><span><i>J. Cao, B. Zhang</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.72 Statistical Mechanics</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.70" title="5.70[J]" class="bubblelink code" onclick="return showCourse(this, '5.70');">5.70[J]</a> or permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: G (Spring; second half of term)<br/> Acad Year 2025-2026: Not offered</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Principles and methods of statistical mechanics. Classical and quantum statistics, grand ensembles, fluctuations, molecular distribution functions, and other topics in equilibrium statistical mechanics. Topics in thermodynamics and statistical mechanics of irreversible processes. </p> <p class="courseblockinstructors seemore"><span><i>J. Cao. B. Zhang</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.73 Introductory Quantum Mechanics I</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.611" title="5.611" class="bubblelink code" onclick="return showCourse(this, '5.611');">5.611</a>, <a href="/search/?P=5.612" title="5.612" class="bubblelink code" onclick="return showCourse(this, '5.612');">5.612</a>, <a href="/search/?P=8.03" title="8.03" class="bubblelink code" onclick="return showCourse(this, '8.03');">8.03</a>, and <a href="/search/?P=18.03" title="18.03" class="bubblelink code" onclick="return showCourse(this, '18.03');">18.03</a> </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Presents the fundamental concepts of quantum mechanics: wave properties, uncertainty principles, Schrodinger equation, and operator and matrix methods. Includes applications to one-dimensional potentials (harmonic oscillator), three-dimensional centrosymetric potentials (hydrogen atom), and angular momentum and spin. Approximation methods include WKB, variational principle, and perturbation theory. </p> <p class="courseblockinstructors seemore"><span><i>M. Bawendi</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.74 Introductory Quantum Mechanics II</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.73" title="5.73" class="bubblelink code" onclick="return showCourse(this, '5.73');">5.73</a> </span><br/><span class="courseblockterms">G (Spring)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Time-dependent quantum mechanics and spectroscopy. Topics include perturbation theory, two-level systems, light-matter interactions, relaxation in quantum systems, correlation functions and linear response theory, and nonlinear spectroscopy. </p> <p class="courseblockinstructors seemore"><span><i>K. Nelson, G. Schlau-Cohen</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.78 Biophysical Chemistry Techniques</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Subject meets with <a href="/search/?P=7.71" title="7.71" class="bubblelink code" onclick="return showCourse(this, '7.71');">7.71</a></span><br/><span class="courseblockprereq">Prereq: <a href="/search/?P=5.07" title="5.07[J]" class="bubblelink code" onclick="return showCourse(this, '5.07');">5.07[J]</a> or <a href="/search/?P=7.05" title="7.05" class="bubblelink code" onclick="return showCourse(this, '7.05');">7.05</a> </span><br/><span class="courseblockterms">Acad Year 2024-2025: G (Spring)<br/> Acad Year 2025-2026: Not offered</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Presents principles of macromolecular crystallography that are essential for structure determinations. Topics include crystallization, diffraction theory, symmetry and space groups, data collection, phase determination methods, model building, and refinement. Discussion of crystallography theory complemented with exercises such as crystallization, data processing, and model building. Meets with <a href="/search/?P=7.71" title="7.71" class="bubblelink code" onclick="return showCourse(this, '7.71');">7.71</a> when offered concurrently. Enrollment limited.</p> <p class="courseblockinstructors seemore"><span><i>C. Drennan</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.80 Advanced Topics of Current Special Interest</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Fall, Spring)</span><br/><span class="courseblockhours">Units arranged</span> </p> <p class="courseblockdesc">Advanced topics of current special interest. </p> <p class="courseblockinstructors seemore"><span><i>Staff</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.81[J] United States Energy Policy: Lessons Learned for the Future</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=15.029J" title="15.029[J]" class="bubblelink code" onclick="return showCourse(this, '15.029J');">15.029[J]</a><br/> Subject meets with <a href="/search/?P=5.811J" title="5.811[J]" class="bubblelink code" onclick="return showCourse(this, '5.811J');">5.811[J]</a>, <a href="/search/?P=15.0291J" title="15.0291[J]" class="bubblelink code" onclick="return showCourse(this, '15.0291J');">15.0291[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Fall; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Compares the US policy responses, from the Nixon administration to the current administration, on issues ranging from oil import dependence to nuclear nonproliferation. Examines what lessons were learned from these issues and how they have shaped the country's current climate change policy. Prepares students to be informed and effective participants in policy deliberations that require difficult decisions and trade-offs. Addresses both domestic and international policy aspects. Students taking graduate version complete additional assignments. </p> <p class="courseblockinstructors seemore"><span><i>J. Deutch</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.811[J] United States Energy Policy: Lessons Learned for the Future</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=15.0291J" title="15.0291[J]" class="bubblelink code" onclick="return showCourse(this, '15.0291J');">15.0291[J]</a><br/> Subject meets with <a href="/search/?P=5.81J" title="5.81[J]" class="bubblelink code" onclick="return showCourse(this, '5.81J');">5.81[J]</a>, <a href="/search/?P=15.029J" title="15.029[J]" class="bubblelink code" onclick="return showCourse(this, '15.029J');">15.029[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: U (Fall; second half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Compares the US policy responses, from the Nixon administration to the current administration, on issues ranging from oil import dependence to nuclear nonproliferation. Examines what lessons were learned from these issues and how they have shaped the country's current climate change policy. Prepares students to be informed and effective participants in policy deliberations that require difficult decisions and trade-offs. Addresses both domestic and international policy aspects. Students taking graduate version complete additional assignments. </p> <p class="courseblockinstructors seemore"><span><i>J. Deutch</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.83 Advanced NMR Spectroscopy</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.73" title="5.73" class="bubblelink code" onclick="return showCourse(this, '5.73');">5.73</a> or permission of instructor </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Spring; first half of term)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Offers a classical and quantum mechanical description of nuclear magnetic resonance (NMR) spectroscopy. The former includes key concepts such as nuclear spin magnetic moment, Larmor precession, Bloch equations, the rotating frame, radio-frequency pulses, vector model of pulsed NMR, Fourier transformation in 1D and nD NMR, orientation dependence of nuclear spin frequencies, and NMR relaxation. The latter covers nuclear spin Hamiltonians, density operator and its time evolution, the interaction representation, Average Hamiltonian Theory for multi-pulse experiments, and analysis of some common pulse sequences in solution and solid-state NMR. </p> <p class="courseblockinstructors seemore"><span><i>R. Griffin</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.891 Independent Study in Chemistry for Undergraduates</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Fall, IAP, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Program of independent study under direction of Chemistry faculty member. May not substitute for required courses for the Chemistry major or minor. </p> <p class="courseblockinstructors seemore"><span><i>Staff</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.892 Independent Study in Chemistry for Undergraduates</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Fall, IAP, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged [P/D/F]</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Program of independent study under direction of Chemistry faculty member. May not substitute for required courses for the Chemistry major or minor. </p> <p class="courseblockinstructors seemore"><span><i>Staff</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.893 Practical Internship Experience in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Summer)</span><br/><span class="courseblockhours">0-1-0 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">For Course 5 and 5-7 students participating in curriculum-related off-campus internship experiences in chemistry. Before enrolling, students must consult the Chemistry Education Office for details on procedures and restrictions, and have approval from their faculty advisor. Subject to department approval. Upon completion, the student must submit a write-up of the experience, approved by their faculty advisor. </p> <p class="courseblockinstructors seemore"><span><i>J. Weisman</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.90 Problems in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">G (Fall, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged [P/D/F]</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Directed research and study of special chemical problems. For Chemistry graduate students only. </p> <p class="courseblockinstructors seemore"><span><i>J. Weisman</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.91 Teaching Experience in the Chemical Sciences</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">G (Fall, Spring)</span><br/><span class="courseblockhours">Units arranged [P/D/F]</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">For students in the chemistry graduate program while teaching. Classroom or laboratory teaching under the supervision of a faculty member and classroom-based instruction on timely topics related to education and modern teaching practices. Limited to chemistry graduate students who are teaching the same term.</p> <p class="courseblockinstructors seemore"><span><i>L. Nolan</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.913 Seminar in Organic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">G (Fall, Spring)</span><br/><span class="courseblockhours">1-0-0 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Discusses current journal publications in organic chemistry. </p> <p class="courseblockinstructors seemore"><span><i>R. L. Danheiser</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.921 Seminar in Chemical Biology</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">G (Fall, Spring)</span><br/><span class="courseblockhours">1-0-0 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Discusses topics of current interest in chemical biology. </p> <p class="courseblockinstructors seemore"><span><i>M. Shoulders, R. Raines</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.931 Seminar in Physical Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: 5.60 </span><br/><span class="courseblockterms">G (Fall, Spring)</span><br/><span class="courseblockhours">1-0-0 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Discusses topics of current interest in physical chemistry. </p> <p class="courseblockinstructors seemore"><span><i>A. Willard</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.941 Seminar in Inorganic Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: <a href="/search/?P=5.03" title="5.03" class="bubblelink code" onclick="return showCourse(this, '5.03');">5.03</a> </span><br/><span class="courseblockterms">G (Fall, Spring)</span><br/><span class="courseblockhours">1-0-0 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Discusses current research in inorganic chemistry. </p> <p class="courseblockinstructors seemore"><span><i>M. Dinca</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.95[J] Teaching College-Level Science and Engineering</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=1.95J" title="1.95[J]" class="bubblelink code" onclick="return showCourse(this, '1.95J');">1.95[J]</a>, <a href="/search/?P=7.59J" title="7.59[J]" class="bubblelink code" onclick="return showCourse(this, '7.59J');">7.59[J]</a>, <a href="/search/?P=8.395J" title="8.395[J]" class="bubblelink code" onclick="return showCourse(this, '8.395J');">8.395[J]</a>, <a href="/search/?P=18.094J" title="18.094[J]" class="bubblelink code" onclick="return showCourse(this, '18.094J');">18.094[J]</a><br/> Subject meets with <a href="/search/?P=2.978" title="2.978" class="bubblelink code" onclick="return showCourse(this, '2.978');">2.978</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Fall)</span><br/><span class="courseblockhours">2-0-2 units</span> </p> <p class="courseblockdesc">Participatory seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. Topics include theories of adult learning; course development; promoting active learning, problemsolving, and critical thinking in students; communicating with a diverse student body; using educational technology to further learning; lecturing; creating effective tests and assignments; and assessment and evaluation. Students research and present a relevant topic of particular interest. Appropriate for both novices and those with teaching experience. </p> <p class="courseblockinstructors seemore"><span><i>J. Rankin</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.961[J] Leadership and Professional Strategies & Skills Training (LEAPS), Part I: Advancing Your Professional Strategies and Skills</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=8.396J" title="8.396[J]" class="bubblelink code" onclick="return showCourse(this, '8.396J');">8.396[J]</a>, <a href="/search/?P=9.980J" title="9.980[J]" class="bubblelink code" onclick="return showCourse(this, '9.980J');">9.980[J]</a>, <a href="/search/?P=12.396J" title="12.396[J]" class="bubblelink code" onclick="return showCourse(this, '12.396J');">12.396[J]</a>, <a href="/search/?P=18.896J" title="18.896[J]" class="bubblelink code" onclick="return showCourse(this, '18.896J');">18.896[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Spring; second half of term)</span><br/><span class="courseblockhours">2-0-1 units</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=8.396J" title="8.396[J]" class="bubblelink code" onclick="return showCourse(this, '8.396J');">8.396[J]</a>. Limited to 80.</p> <p class="courseblockinstructors seemore"><span><i>A. Frebel</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.962[J] Leadership and Professional Strategies & Skills Training (LEAPS), Part II: Developing Your Leadership Competencies</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=8.397J" title="8.397[J]" class="bubblelink code" onclick="return showCourse(this, '8.397J');">8.397[J]</a>, <a href="/search/?P=9.981J" title="9.981[J]" class="bubblelink code" onclick="return showCourse(this, '9.981J');">9.981[J]</a>, <a href="/search/?P=12.397J" title="12.397[J]" class="bubblelink code" onclick="return showCourse(this, '12.397J');">12.397[J]</a>, <a href="/search/?P=18.897J" title="18.897[J]" class="bubblelink code" onclick="return showCourse(this, '18.897J');">18.897[J]</a></span><br/><span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Spring; first half of term)</span><br/><span class="courseblockhours">2-0-1 units</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=8.397J" title="8.397[J]" class="bubblelink code" onclick="return showCourse(this, '8.397J');">8.397[J]</a>. Limited to 80.</p> <p class="courseblockinstructors seemore"><span><i>D. Rigos</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.S00 Special Subject in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Fall; second half of term)<br/> Not offered regularly; consult department</span><br/><span class="courseblockhours">Units arranged</span> </p> <p class="courseblockdesc">Organized lecture, subject consisting of material in the broadly-defined field of chemistry not offered in regularly scheduled subjects. </p> <p class="courseblockinstructors seemore"><span><i>J. Deutch</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.S64 Special Subject in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">G (Spring; first half of term)<br/> Not offered regularly; consult department</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Organized lecture consisting of material in the broadly-defined field of chemistry not offered in regularly scheduled subjects. </p> <p class="courseblockinstructors seemore"><span><i>X. Wang</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.S72 Special Subject in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Spring)</span><br/><span class="courseblockhours">3-0-9 units</span> </p> <p class="courseblockdesc">Organized lecture consisting of material in the broadly defined field of chemistry not offered in regularly scheduled subjects. </p> <p class="courseblockinstructors seemore"><span><i>J. Cao, B. Zhang</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.S75 Special Subject in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Spring)</span><br/><span class="courseblockhours">2-0-4 units</span> </p> <p class="courseblockdesc">Organized lecture consisting of material in the broadly-defined field of chemistry not offered in regularly scheduled subjects. </p> <p class="courseblockinstructors seemore"><span><i>K. Nelson</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.S95 Special Subject in Chemistry</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">Acad Year 2024-2025: Not offered<br/> Acad Year 2025-2026: G (Fall, Spring)</span><br/><span class="courseblockhours">1-0-1 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Organized lecture consisting of material in the broadly-defined field of chemistry not offered in regularly scheduled subjects. </p> <p class="courseblockinstructors seemore"><span><i>B. Hansberry</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.THG Graduate Thesis</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">G (Fall, IAP, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Program of research leading to the writing of a PhD thesis; to be arranged by the student and an appropriate MIT faculty member. </p> <p class="courseblockinstructors seemore"><span><i>J. Weisman</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.THU Undergraduate Thesis</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">U (Fall, IAP, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Program of original research under supervision of a chemistry faculty member, culminating with the preparation of a thesis. Ordinarily requires equivalent of two terms of research with chemistry department faculty member. </p> <p class="courseblockinstructors seemore"><span><i>Staff</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.UAR[J] Climate and Sustainability Undergraduate Advanced Research</strong></span></h4> <p class="courseblockextra"> <span class="courseblockcluster">Same subject as <a href="/search/?P=1.UARJ" title="1.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '1.UARJ');">1.UAR[J]</a>, <a href="/search/?P=3.UARJ" title="3.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '3.UARJ');">3.UAR[J]</a>, <a href="/search/?P=11.UARJ" title="11.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '11.UARJ');">11.UAR[J]</a>, <a href="/search/?P=12.UARJ" title="12.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '12.UARJ');">12.UAR[J]</a>, <a href="/search/?P=15.UARJ" title="15.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '15.UARJ');">15.UAR[J]</a>, <a href="/search/?P=22.UARJ" title="22.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '22.UARJ');">22.UAR[J]</a></span><br/><span class="courseblockprereq">Prereq: Permission of instructor </span><br/><span class="courseblockterms">U (Fall, Spring)</span><br/><span class="courseblockhours">2-0-4 units</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">See description under subject <a href="/search/?P=1.UARJ" title="1.UAR[J]" class="bubblelink code" onclick="return showCourse(this, '1.UARJ');">1.UAR[J]</a>. Application required; consult MCSC website for more information.</p> <p class="courseblockinstructors seemore"><span><i>D. Plata, E. Olivetti</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.UR Undergraduate Research</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Fall, IAP, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged [P/D/F]</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Program of research to be arranged by the student and a departmental faculty member. Research can be applied toward undergraduate thesis. </p> <p class="courseblockinstructors seemore"><span><i>A. Radosevich</i></span></p> </div><div class="courseblock"> <h4 class="courseblocktitle"><span font="Meta Pro"><strong>5.URG Undergraduate Research</strong></span></h4> <p class="courseblockextra"> <span class="courseblockprereq">Prereq: None </span><br/><span class="courseblockterms">U (Fall, IAP, Spring, Summer)</span><br/><span class="courseblockhours">Units arranged</span><br/><span class="courseblockoptional">Can be repeated for credit.</span> </p> <p class="courseblockdesc">Program of research to be arranged by the student and a departmental faculty member. May be taken for up to 12 units per term, not to exceed a cumulative total of 48 units. A 10-page paper summarizing research is required. </p> <p class="courseblockinstructors seemore"><span><i>A. Radosevich</i></span></p> </div></div> </div> </div>  </div> </div>  <div id="footer" role="contentinfo"> <div class="wrap"> <div id="footer-links"> <a href="http://mitadmissions.org/apply" target="_blank">Admissions</a><a href="http://sfs.mit.edu/" target="_blank">Financial Aid</a><a href="http://web.mit.edu/registrar/" target="_blank">Registrar</a><a href="http://web.mit.edu/iap/" target="_blank">IAP</a><a href="/summer/">Summer</a><a href="http://professional.mit.edu" target="_blank">Professional Education</a><a href="https://www.edx.org/school/mitx" class="mitx" target="_blank">MITx</a><a href="https://outreach.mit.edu/" target="_blank">K-12</a><a href="http://whereis.mit.edu/" target="_blank">Campus Map</a><br/><a href="https://officesdirectory.mit.edu/" target="_blank">Directories</a><a href="/about-bulletin/">About the Bulletin</a><a href="/nondiscrimination-policy/">Nondiscrimination Policy</a><a href="/changelog/">Changes</a><a href="/help/">Help</a><a href="https://accessibility.mit.edu/" target="_blank">Accessibility</a> </div> <div id="footer-branding" class="clearfix"> <div class="foot-col" id="right"> <div id="footer-mit-logo"><img src="/images/mit-logo-footer.svg" alt="MIT" width="185px" /></div> </div> <div class="foot-col" id="left"> <div id="footer-bulletin"><img src="/images/mit-bulletin-logo-footer-24-25.png" alt="MIT Academic Bulletin" /></div> <div id="footer-contact">77 Massachusetts Avenue<br/>Cambridge, MA 02139-4307</div> </div> </div> </div> <a href="#header" id="totop"><span class="sr-only">Back to top</span></a> </div>  <div id="print-dialog" class="screen noscript" role="dialog"> <div class="print-header"> Print Options </div> <div class="print-body"> <div class="print-option"> <div class="option-head"> <a href="#" onclick="hidePrintDialog();window.print();return false">Send Page to Printer</a> </div> <p> <em>Print this page.</em> </p> </div> <div class="print-option"><div class="option-head"><a href="5.pdf" target="_blank">Download PDF of this Page</a></div><p><em>The PDF includes all information on this page and its related tabs. 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