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Search results for: G. Surpris
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Surpris</title> <meta name="description" content="Search results for: G. Surpris"> <meta name="keywords" content="G. Surpris"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="G. 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Surpris"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: G. Surpris</h1> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Fractal Dimension of Breast Cancer Cell Migration in a Wound Healing Assay</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=R.%20Sullivan">R. Sullivan</a>, <a href="https://publications.waset.org/search?q=T.%20Holden"> T. Holden</a>, <a href="https://publications.waset.org/search?q=G.%20Tremberger"> G. Tremberger</a>, <a href="https://publications.waset.org/search?q=Jr"> Jr</a>, <a href="https://publications.waset.org/search?q=E.%20Cheung"> E. Cheung</a>, <a href="https://publications.waset.org/search?q=C.%20Branch"> C. Branch</a>, <a href="https://publications.waset.org/search?q=J.%20Burrero"> J. Burrero</a>, <a href="https://publications.waset.org/search?q=G.%20Surpris"> G. Surpris</a>, <a href="https://publications.waset.org/search?q=S.%20Quintana"> S. Quintana</a>, <a href="https://publications.waset.org/search?q=A.%20Rameau"> A. Rameau</a>, <a href="https://publications.waset.org/search?q=N.%20Gadura"> N. Gadura</a>, <a href="https://publications.waset.org/search?q=H.%20Yao"> H. Yao</a>, <a href="https://publications.waset.org/search?q=R.%20Subramaniam"> R. Subramaniam</a>, <a href="https://publications.waset.org/search?q=P.%20Schneider"> P. Schneider</a>, <a href="https://publications.waset.org/search?q=S.%20A.%20Rotenberg"> S. A. Rotenberg</a>, <a href="https://publications.waset.org/search?q=P.%20Marchese"> P. Marchese</a>, <a href="https://publications.waset.org/search?q=A.%20Flamhlolz"> A. Flamhlolz</a>, <a href="https://publications.waset.org/search?q=D.%20Lieberman"> D. Lieberman</a>, <a href="https://publications.waset.org/search?q=T.%20Cheung"> T. Cheung</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Migration in breast cancer cell wound healing assay had been studied using image fractal dimension analysis. The migration of MDA-MB-231 cells (highly motile) in a wound healing assay was captured using time-lapse phase contrast video microscopy and compared to MDA-MB-468 cell migration (moderately motile). The Higuchi fractal method was used to compute the fractal dimension of the image intensity fluctuation along a single pixel width region parallel to the wound. The near-wound region fractal dimension was found to decrease three times faster in the MDA-MB- 231 cells initially as compared to the less cancerous MDA-MB-468 cells. The inner region fractal dimension was found to be fairly constant for both cell types in time and suggests a wound influence range of about 15 cell layer. The box-counting fractal dimension method was also used to study region of interest (ROI). The MDAMB- 468 ROI area fractal dimension was found to decrease continuously up to 7 hours. The MDA-MB-231 ROI area fractal dimension was found to increase and is consistent with the behavior of a HGF-treated MDA-MB-231 wound healing assay posted in the public domain. A fractal dimension based capacity index has been formulated to quantify the invasiveness of the MDA-MB-231 cells in the perpendicular-to-wound direction. Our results suggest that image intensity fluctuation fractal dimension analysis can be used as a tool to quantify cell migration in terms of cancer severity and treatment responses. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Higuchi%20fractal%20dimension" title="Higuchi fractal dimension">Higuchi fractal dimension</a>, <a href="https://publications.waset.org/search?q=box-counting%20fractal%20dimension" title=" box-counting fractal dimension"> box-counting fractal dimension</a>, <a href="https://publications.waset.org/search?q=cancer%20cell%20migration" title=" cancer cell migration"> cancer cell migration</a>, <a href="https://publications.waset.org/search?q=wound%20healing." title=" wound healing."> wound healing.</a> </p> <a href="https://publications.waset.org/4794/fractal-dimension-of-breast-cancer-cell-migration-in-a-wound-healing-assay" class="btn btn-primary btn-sm">Procedia</a> <a 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