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Find the right office to meet your needs.</div></li></ul></li><li class="top-menu-divider three"><ul><li><a href="https://www.renishaw.com/en/15545.aspx"><span class="nav-title">Supplier portal</span></a><div class="nav-desc">Information for suppliers, or potential suppliers, to Renishaw.</div></li></ul></li></ul></li></ul></nav><nav id="bc-bar" itemscope="" itemtype="http://data-vocabulary.org/Breadcrumb" role="navigation"><div class="bc-inner"><a class="bc-link" href="/en/renishaw-enhancing-efficiency-in-manufacturing-and-healthcare--1030" itemprop="url"><span itemprop="title">Home</span></a><span class="bc-spacer">-</span><a class="bc-link" href="/en/neurosurgery-products-and-systems--6332" itemprop="url"><span itemprop="title">Neurosurgery products and systems</span></a><span class="bc-spacer">-</span><strong class="bc-current">neuroinfuse™</strong></div></nav><article id="main"><h1 id="page-title">neuroinfuse™ drug delivery system</h1><div id="Region64" class="region"><div class="region-inner"><div id="ElementHTML123629" class="sb-style-hero-text grid g1 sb-element-type-html"><div class="htmlInner"><p>Novel chronic and acute catheter systems for direct delivery of therapeutics to the brain</p></div></div></div></div><div id="Region63" style="background-image:url(/media/img/gen/58e27ad96e0b49ab9c7a343e35fe9788.jpg);background-repeat:no-repeat;background-position:50% 0;min-height:350px;*height:350px" class="region"><div class="region-inner"></div></div><div id="Region17" class="region"><div class="region-inner"><div id="ElementHTML123664" class="grid g1 sb-element-type-html"><div class="htmlInner"><h2>Crossing the blood-brain barrier</h2><p>Intraparenchymal drug delivery offers a practical method of bypassing the blood-brain barrier (BBB) and shows great promise in providing the next step change in the treatment of neurodegenerative, neuro oncology and other debilitating neurological conditions.</p><p>We are developing a patented range of engineering solutions to cover chronic (long term) implantable and acute (short term) implantable intraparenchymal drug delivery. Our low dead volume chronic device has a novel, MRI compatible, transcutaneous port that aims to provide a solution for simultaneous intermittent drug delivery to the central nervous system (CNS) through multiple catheters (up to four) at any time interval. </p></div></div><div id="ElementMediaList125748" class="media512wide grid g4 two"><h2 class="medialist-title">Watch an introductory video</h2> <ul class="medialist" id="UlMediaList125748"> <li class="medialist-row media-file mp4 MediaApproved medialist-item-lang video"> <div class="media-vid-outer" style="height: 288px; width: 512px;"><div class="media-vid-wrapper mediaVid264728" id="125748_0" style="width:512px;"><a id="ml-hover-a8391ad700a54c0284fa10253303354b" class="media-vid-player" style="height: 288px; width: 512px;" href="/media/video/en/be390bba4e70402a879835712b16ca64.mp4" title="The neuroinfuse™ drug delivery system"><img src="/media/thumbnails/512wide/be390bba4e70402a879835712b16ca64.jpg" /><div class="media-vid-play"><div>Play</div></div></a></div></div><span class="media-list-item-title"> <a id="ml-titlelink-a8391ad700a54c0284fa10253303354b" class="medialist-title" href="/media/video/en/be390bba4e70402a879835712b16ca64.mp4">The neuroinfuse™ drug delivery system</a></span> <div class="mediaGallery-item-hidden-div MediaApproved" id="ml-hover-a8391ad700a54c0284fa10253303354b_desc" style="display:none;"> <span class="sb-player-thumbnail mp4"> <a title="The neuroinfuse™ drug delivery system" href="https://www.renishaw.com/resourcecentre/en/download/the-neuroinfuse-drug-delivery-system--99717" class="mediaitem hideOnHover"> <img class="mediaGalleryThumb" src="/media/thumbnails/100/be390bba4e70402a879835712b16ca64.jpg" alt="The neuroinfuse™ drug delivery system" /> </a> </span> <h3 class="sb-player-title hideOnHover"><a title="The neuroinfuse™ drug delivery system" href="https://www.renishaw.com/resourcecentre/en/download/the-neuroinfuse-drug-delivery-system--99717">The neuroinfuse™ drug delivery system</a></h3> <p class="sbplayer-description hideOnHover">Intraparenchymal drug delivery offers a practical method of bypassing the blood-brain-barrier and shows great promise in providing the next step change in the treatment of neurodegenerative, neuro oncology and other debilitating neurological conditions.</p> <span class="sb-player-dimensions medialist-dimensions hideOnHover">[1920 x 1080]</span> <span class="sb-player-filesize medialist-filesize hideOnHover">[194.8MB]</span> </div> </li> </ul> </div> <div id="ElementMediaList131214" class="media490wide grid g4 two"><h2 class="medialist-title">A complete robotic platform</h2> <ul class="medialist" id="UlMediaList131214"> <li class="medialist-row media-file mp4 MediaApproved medialist-item-lang video"> <div class="media-vid-outer" style="height: 276px; width: 490px;"><div class="media-vid-wrapper mediaVid264978" id="131214_0" style="width:490px;"><a id="ml-hover-5b18492e1e6841f6a2d60c0d23face54" class="media-vid-player" style="height: 276px; width: 490px;" href="/media/video/en/f52af904bbea4595818bc2aa9effdc49.mp4" title="SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS"><img src="/media/thumbnails/490wide/f52af904bbea4595818bc2aa9effdc49.jpg" /><div class="media-vid-play"><div>Play</div></div></a></div></div><span class="media-list-item-title"> <a id="ml-titlelink-5b18492e1e6841f6a2d60c0d23face54" class="medialist-title" href="/media/video/en/f52af904bbea4595818bc2aa9effdc49.mp4">SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS</a></span> <div class="mediaGallery-item-hidden-div MediaApproved" id="ml-hover-5b18492e1e6841f6a2d60c0d23face54_desc" style="display:none;"> <span class="sb-player-thumbnail mp4"> <a title="SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS" href="https://www.renishaw.com/resourcecentre/en/download/sno-scidot-joint-conference-on-therapeutic-delivery-to-the-cns--100052" class="mediaitem hideOnHover"> <img class="mediaGalleryThumb" src="/media/thumbnails/100/f52af904bbea4595818bc2aa9effdc49.jpg" alt="SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS" /> </a> </span> <h3 class="sb-player-title hideOnHover"><a title="SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS" href="https://www.renishaw.com/resourcecentre/en/download/sno-scidot-joint-conference-on-therapeutic-delivery-to-the-cns--100052">SNO-SCIDOT Joint Conference on Therapeutic Delivery to the CNS</a></h3> <p class="sbplayer-description hideOnHover">Clinical Sales Development Manager Stuart Campbell and Consultant Neurosurgeon Steven Gill present Renishaw’s range of products for neurosurgery at the SNO-SCIDOT conference in San Francisco, California.</p> <span class="sb-player-dimensions medialist-dimensions hideOnHover">[1920 x 1080]</span> <span class="sb-player-filesize medialist-filesize hideOnHover">[161.2MB]</span> </div> </li> </ul> </div> <div id="ElementHTML137264" class="grid g1 sb-element-type-html"><div class="htmlInner"><h2>Features and benefits </h2><table width="100%" border="1" cellspacing="0" cellpadding="1"><tbody><tr><td><p>Feature</p></td><td>Benefit</td></tr><tr><td>Implantation performed outside of MRI</td><td>Reduces the burden on costly MRI equipment and radiologists</td></tr><tr><td>MRI compatible</td><td>Enables real-time imaging of infusions</td></tr><tr><td>Acute infusions</td><td>Suitable for one-off infusions, catheter can be explanted after use</td></tr><tr><td>Chronic infusions</td><td>Enables repeated infusions and flexible administration regimes</td></tr><tr><td>Patient specific</td><td>Catheter length can be adjusted to encourage custom therapy distribution</td></tr><tr><td>4-channel re-accessible catheter system with independent fluid paths and flow rates</td><td>Allows the clinician to control and customise the therapy<br />regime</td></tr><tr><td>Repeat administrations do not require additional surgery</td><td>Reduces inherent risk of repeated surgery</td></tr><tr><td>Repeated delivery of fixed volumes</td><td>Aims to deliver consistent and repeatable treatment</td></tr><tr><td>Outpatient infusions</td><td>Reduces strain on in-patient facilities</td></tr></tbody></table></div></div><div id="ElementHTML123665" class="grid g1 sb-element-type-html"><div class="htmlInner"><h2>Working with clinical partners</h2><p>Over several years Renishaw has been working with experienced clinical experts to produce a specification for an intraparenchymal drug delivery device and stereotactic delivery platform that facilitates convection enhanced delivery (CED) and other infusion applications.</p><p>The chronic product is currently undergoing clinical investigation as part of the Horizon 2020 funded <a href="https://treater.eu/about-project/" target="_blank">TreatER</a> project. TreatER is a first-in-human clinical study examining the intraparenchymal delivery of CDNF for the treatment of Parkinson's disease. </p></div></div><div id="ElementNavigation130298" class="grid g1 sb-element-type-navigation"><h2 class="nav-cta-title"></h2><div class="nav-cta nav-size-1" style="Width:100%"><a class="nav-item nav-single item-width-auto" href="https://treater.eu/about-project/" target="_blank" title="Visit TreatER website">Visit TreatER website</a></div></div> <div id="ElementHTML144115" class="sb-style-cta grid g1 sb-element-type-html"><div class="htmlInner"><h2>Drug development opportunities</h2><p>At present, the Renishaw neuroinfuse chronic and acute drug delivery system can only be used in the setting of an approved clinical trial. </p><p>Renishaw is currently seeking academic, clinical and commercial partners across a wide range of indications, from oncology to neurodegenerative diseases. </p><p>The purpose of this website is only to obtain partners and not to make the device generally available.</p></div></div><div id="ElementNavigation144116" class="sb-style-image-borders grid g1 sb-element-type-navigation"><h2 class="nav-cta-title"></h2><div class="nav-cta nav-size-1" style="Width:100%"><a href="/en/lab2clinic-central-nervous-system-cns-drug-delivery-service--44803" class="nav-item nav-single item-width-auto" target="_self" title="">More about our strategy</a></div></div> <div id="ElementNavigation135843" class="sb-style-image-borders grid g1 sb-element-type-navigation"><h2 class="nav-cta-title">Want to find out more?</h2><div class="nav-cta nav-size-1" style="Width:100%"><a class="nav-item nav-single item-width-auto" href="https://www.renishaw.com/en/online-request--7400?purpose=9&productname=Neurological&productline=12&pageorigin=footer" target="_self" title="">Contact us online</a></div></div> <div id="ElementMediaGallery131000" class="mediaGalleryWrapper media180wide mediaGridGallery grid g4 one"> <h2 class="mediaGalleryHeading">Downloads</h2> <ul class="mediaGallery file-thumbs-30px mediaGalleryGrid" id="ElementMediaGalleryList131000"> <li class="mediaGallery MediaApproved pdfFile pdf"> <a id="ml-image-link-82e6886f335a40b6a7022ba4b83ab5ff" class="mediaitem mediaDirect mediaGallery-thumb" href="/media/pdf/en/19f9c27d4e624cbdb43fa967b1e84574.pdf"> <img class="mediaGalleryThumb" src="/media/thumbnails/180wide/19f9c27d4e624cbdb43fa967b1e84574.jpg" alt="Flyer: neuroinfuse™ intraparenchymal drug delivery system" /> </a> <a class="mediaGallery-title" href="/media/pdf/en/19f9c27d4e624cbdb43fa967b1e84574.pdf">Flyer: neuroinfuse™ intraparenchymal drug delivery system</a> <div class="mediaGallery-item-hidden-div MediaApproved" id="ml-hover-82e6886f335a40b6a7022ba4b83ab5ff_desc" style="display:none;"> <span class="sb-player-thumbnail pdf"> <a title="Flyer: neuroinfuse™ intraparenchymal drug delivery system" href="https://www.renishaw.com/resourcecentre/en/download/flyer-neuroinfuse-intraparenchymal-drug-delivery-system--100797" class="mediaitem hideOnHover"> <img class="mediaGalleryThumb" src="/media/thumbnails/100/19f9c27d4e624cbdb43fa967b1e84574.jpg" alt="Flyer: neuroinfuse™ intraparenchymal drug delivery system" /> </a> </span> <h3 class="sb-player-title hideOnHover"><a title="Flyer: neuroinfuse™ intraparenchymal drug delivery system" href="https://www.renishaw.com/resourcecentre/en/download/flyer-neuroinfuse-intraparenchymal-drug-delivery-system--100797">Flyer: neuroinfuse™ intraparenchymal drug delivery system</a></h3> <p class="sbplayer-description hideOnHover">Renishaw is developing an intraparenchymal drug delivery system which will offer a practical method of bypassing the bloodbrain barrier. The neuroinfuse system is currently in the clinical investigation phase of development and shows great promise in providing a next step change in the treatment of neurodegenerative, neuro-oncology and other debilitating neurological conditions.</p> <span class="sb-player-filesize medialist-filesize hideOnHover">[584kB]</span> </div> </li> </ul> </div> </div></div><div id="Region19" class="region"><div class="region-inner"><div id="ElementHTML153412" class="sb-style-info sb-style-element-separate-below grid g1 sb-element-type-html"><div class="htmlInner"><p>Renishaw Neuro Solutions Limited – Legal and Privacy Notices. <a href="/en/renishaw-neuro-solutions-limited-legal-and-compliance--45655" title="Renishaw Neuro Solutions Limited – Legal and Privacy Notices">Click here</a></p></div></div></div></div><div id="Region108" class="region"><div class="region-inner"></div></div><div id="Region109" class="region"><div class="region-inner"></div></div><div id="Region110" class="region"><div class="region-inner"></div></div><div id="Region111" class="region"><div class="region-inner"></div></div><div id="Region112" class="region"><div class="region-inner"></div></div><div id="Region113" class="region"><div class="region-inner"></div></div><div id="Region114" class="region"><div class="region-inner"></div></div><div id="Region115" class="region"><div class="region-inner"></div></div><div id="Region116" class="region"><div class="region-inner"></div></div><div id="Region117" class="region"><div class="region-inner"></div></div><div class="sb-style-element-separate-above-more"> </div><div id="Region18" class="region sb-style-aside"><div class="region-inner"><div id="ElementNavigation84404" class="grid g4 two sb-element-type-navigation"><h2 class="nav-list-title">Neurological</h2><ul class="nav-list nav-element nav-size-6"><li class="nav-list-item nav-item nav-first item-width-auto"><a href="/en/neurosurgery-products-and-systems--6332" title="" target="_self">Home</a><small class="nav-list-desc"></small></li><li class="nav-list-item nav-item item-width-auto"><a href="/en/--10863" title="" target="_self">Therapies and procedures</a><small class="nav-list-desc"></small></li><li class="nav-list-item nav-item item-width-auto"><a href="/en/--32383" title="" target="_self">Products</a><small class="nav-list-desc"></small></li><li class="nav-list-item nav-item item-width-auto"><a href="/en/research--8238" title="" target="_self">Research</a><small class="nav-list-desc"></small></li><li class="nav-list-item nav-item item-width-auto"><a href="/en/--10854" title="" target="_self">Case stories</a><small class="nav-list-desc"></small></li><li class="nav-list-item nav-item nav-last item-width-auto"><a href="/en/support--41303" title="Support" target="_self">Support</a><small class="nav-list-desc"></small></li></ul></div> </div></div><div id="Region20" class="region"><div class="region-inner"></div></div></article><footer id="page-footer"><div class="footer-content"><div class="grid g3 one footer-news"><h2 class="footer-contact-heading"><a href="/en/neurological-products-and-therapies-news--12485"><span class="footer-section-icon"></span><span class="footer-section-label">Neurological news</span></a></h2><div class="rss-reader-control-main" pageid="12485" applicationid="1" maxresults="2" pageidstoignore="12485" pagelanguage="2" languagecodestoaccept="en" showlargeimage="false" rendertype="footer" ordertype="" hidelanguagelinked="True"></div></div><div class="grid g3 one footer-contact"><h2 class="footer-contact-heading"><a href="/en/contact-us--7400?productname=neuroinfuse%e2%84%a2%20drug%20delivery%20system&productline=12&pageorigin=footer"><span class="footer-section-icon"></span><span class="footer-section-label">Contact Renishaw</span></a></h2><p><a href="/en/contact-us--7400?productname=neuroinfuse%e2%84%a2%20drug%20delivery%20system&productline=12&pageorigin=footer" class="contact-online"><span class="footer-item-icon"></span>Online form</a></p><p><a href="/en/worldwide-offices--6438?productname=neuroinfuse%e2%84%a2%20drug%20delivery%20system&productline=12&pageorigin=footer" class="contact-details"><span class="footer-item-icon"></span>Worldwide offices</a></p><h2 class="footer-myrenishaw"><a href="https://www.renishaw.com/my/" class="contact-online"><span class="footer-section-icon"></span><span class="footer-section-label">MyRenishaw</span></a></h2><h2 class="footer-webshop"><a href="https://www.renishaw.com/shop/home.aspx" target="_blank"><span class="footer-section-icon"></span><span class="footer-section-label">Online store</span></a></h2></div><div class="grid g3 one footer-events"><h2 id="footer-events-heading"><a href="/en/events-and-webinars--45456"><span class="footer-section-icon"></span><span class="footer-section-label">Events and exhibitions</span></a></h2><div id="EventsControl"><ul class="calendar mini" aria-live="polite"></ul></div><script> var url='/api/events/events/calendar/12/2/2?HideDivisions=38'; 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