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Search results for: niosome
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paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Effect of Non-Ionic Surfactants on in vitro Release of Ketorolactromethamine</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ajay%20Aggarwal">Ajay Aggarwal</a>, <a href="https://publications.waset.org/abstracts/search?q=Kamal%20Saroha"> Kamal Saroha</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanju%20Nanda"> Sanju Nanda</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Niosomes or non-ionic surfactant vesicles are microscopic lamellar structures formed on admixture of non-ionic surfactant of the alkyl or dialkyl polyglycerol ether class and cholesterol with subsequent hydration in aqueous media. They are vesicular systems similar to liposomes that can be used as carriers of amphiphilic and lipophilic drugs. Entrapment efficiency was found to be higher in case of niosome prepared with span60 than niosome prepared with tween. The amount of release was found to be in order of Span20>Tween60>Tween20>Span60. As the concentration of surfactant is increased in vitro release was increased due to high entrapment. The stability study of optimized batch revealed that particle size was increased after 3months on increasing the temperature. On the other hand entrapment efficiency was decreased on increasing the temperature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=niosomes" title="niosomes">niosomes</a>, <a href="https://publications.waset.org/abstracts/search?q=vesicles" title=" vesicles"> vesicles</a>, <a href="https://publications.waset.org/abstracts/search?q=span" title=" span"> span</a>, <a href="https://publications.waset.org/abstracts/search?q=tween" title=" tween"> tween</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20vitro%20release" title=" in vitro release"> in vitro release</a> </p> <a href="https://publications.waset.org/abstracts/41358/effect-of-non-ionic-surfactants-on-in-vitro-release-of-ketorolactromethamine" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41358.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">357</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Optimization, Characterization and Stability of Trachyspermum copticum Essential Oil Loaded in Niosome Nanocarriers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohadese%20Hashemi">Mohadese Hashemi</a>, <a href="https://publications.waset.org/abstracts/search?q=Elham%20Akhoundi%20Kharanaghi"> Elham Akhoundi Kharanaghi</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatemeh%20Haghiralsadat"> Fatemeh Haghiralsadat</a>, <a href="https://publications.waset.org/abstracts/search?q=Mojgan%20Yazdani"> Mojgan Yazdani</a>, <a href="https://publications.waset.org/abstracts/search?q=Omid%20Javani"> Omid Javani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahboobe%20Sharafodini"> Mahboobe Sharafodini</a>, <a href="https://publications.waset.org/abstracts/search?q=Davood%20Rajabi"> Davood Rajabi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Niosomes are non-ionic surfactant vesicles in aqueous media resulting in closed bilayer structures that can be used as carriers of hydrophilic and hydrophobic compounds. The use of niosomes for encapsulation of essential oils (EOs) is an attractive new approach to overcome their physicochemical stability concerns include sensibility to oxygen, light, temperature, and volatility, and their reduced bioavailability which is due to low solubility in water. EOs are unstable and fragile volatile compounds which have strong interest in pharmaceutical due to their medicinal properties such as antiviral, anti-inflammatory, antifungal, and antioxidant activities without side effects. Trachyspermum copticum (ajwain) is an annual aromatic plant with important medicinal properties that grows widely around Mediterranean region and south-west Asian countries. The major components of the ajwain oil were reported as thymol, 纬-terpinene, p-cymene, and carvacrol which provide antimicrobial and antioxidant activity. The aim of this work was to formulate ajwain essential oil-loaded niosomes to improve water solubility of natural product and evaluate its physico-chemical features and stability. Ajwain oil was obtained through steam distillation using a clevenger-type apparatus and GC/MS was applied to identify the main components of the essential oil. Niosomes were prepared by using thin film hydration method and nanoparticles were characterized for particle size, dispersity index, zeta potential, encapsulation efficiency, in vitro release, and morphology. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=trachyspermum%20copticum" title="trachyspermum copticum">trachyspermum copticum</a>, <a href="https://publications.waset.org/abstracts/search?q=ajwain" title=" ajwain"> ajwain</a>, <a href="https://publications.waset.org/abstracts/search?q=niosome" title=" niosome"> niosome</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oil" title=" essential oil"> essential oil</a>, <a href="https://publications.waset.org/abstracts/search?q=encapsulation" title=" encapsulation"> encapsulation</a> </p> <a href="https://publications.waset.org/abstracts/33687/optimization-characterization-and-stability-of-trachyspermum-copticum-essential-oil-loaded-in-niosome-nanocarriers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33687.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">481</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Enhancement in Antimicrobial and Antioxidant Activity of Cuminum cyminum L. through Niosome Nanocarries </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatemeh%20Haghiralsadat">Fatemeh Haghiralsadat</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohadese%20Hashemi"> Mohadese Hashemi</a>, <a href="https://publications.waset.org/abstracts/search?q=Elham%20Akhoundi%20Kharanaghi"> Elham Akhoundi Kharanaghi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mojgan%20Yazdani"> Mojgan Yazdani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahboobe%20Sharafodini"> Mahboobe Sharafodini</a>, <a href="https://publications.waset.org/abstracts/search?q=Omid%20Javani"> Omid Javani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Niosomes are colloidal particles formed from the self-assembly of non-ionic surfactants in aqueous medium resulting in closed bilayer structures. As a consequence of this hydrophilic and hydrophobic structure, niosomes have the capacity to entrap compounds of different solubilities. Niosomes are promising vehicle for drug delivery which protect sensitive drugs and improve the therapeutic index of drugs by restricting their action to target cells. Essential oils are complex mixtures of volatile compounds such as terpenoids, phenol-derived aromatic components that have been used for many biological properties including bactericidal, fungicidal, insecticidal, antioxidant, anti-tyrosinase and other medicinal properties. Encapsulation of essential oils in niosomes can be an attractive method to overcome their limitation such as volatility, easily decomposition by heat, humidity, light, or oxygen. Cuminum cyminum L. (Cumin) is an aromatic plant included in the Apiaceae family and is used to flavor foods, added to fragrances, and for medical preparations which is indigenous to Egypt, the Mediterranean region, Iran and India. The major components of the Cumin oil were reported as cuminaldehyde, 纬 -terpinene, 尾-pinene, p-cymene, p-mentha-1, 3-dien-7-al, and p-mentha-1, 4-dien-7-al which provide the antimicrobial and antioxidant activity. The aim of this work was to formulate Cumin essential oil-loaded niosomes to improve water solubility of natural product and evaluate its physico-chemical features and stability. Cumin oil was obtained through steam distillation using a clevenger-type apparatus and GC/MS was applied to identify the main components of the essential oil. Niosomes were prepared by using thin film hydration method and nanoparticles were characterized for particle size, dispersity index, zeta potential, encapsulation efficiency, in vitro release, and morphology. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Cuminum%20cyminum%20L." title="Cuminum cyminum L.">Cuminum cyminum L.</a>, <a href="https://publications.waset.org/abstracts/search?q=Cumin" title=" Cumin"> Cumin</a>, <a href="https://publications.waset.org/abstracts/search?q=niosome" title=" niosome"> niosome</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oil" title=" essential oil"> essential oil</a>, <a href="https://publications.waset.org/abstracts/search?q=encapsulation" title=" encapsulation"> encapsulation</a> </p> <a href="https://publications.waset.org/abstracts/33689/enhancement-in-antimicrobial-and-antioxidant-activity-of-cuminum-cyminum-l-through-niosome-nanocarries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33689.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">515</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Effect of Span 60, Labrasol, and Cholesterol on Labisia pumila Loaded Niosomes Quality</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Binti%20Ya%E2%80%99akob">H. Binti Ya鈥檃kob</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Siew%20Chin"> C. Siew Chin</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Abd%20Aziz"> A. Abd Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Ware"> I. Ware</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Fauzi%20Abd%20Jalil"> M. Fauzi Abd Jalil</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Rashidah%20Ahmed"> N. Rashidah Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Sabtu"> R. Sabtu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <em>Labisia pumila</em> (LP) plant extract has the potential to be applied in cosmeceutical products due to its anti-photoaging properties. The main purpose of this study was to improve transdermal delivery of LP by encapsulating LP in niosomes. Niosomes loaded LPs were prepared by coacervation phase separation method using non-ionic surfactant (Span 60), labrasol, and cholesterol. The optimum formula obtained were Span 60, labrasol and cholesterol at the mole ratio of 6:1:4. At the optimum formulation, the niosome obtained significantly improved the quality of transdermal penetration of LP compared to free LP. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Labisia%20pumila" title="Labisia pumila">Labisia pumila</a>, <a href="https://publications.waset.org/abstracts/search?q=niosomes" title=" niosomes"> niosomes</a>, <a href="https://publications.waset.org/abstracts/search?q=transdermal" title=" transdermal"> transdermal</a>, <a href="https://publications.waset.org/abstracts/search?q=quality" title=" quality"> quality</a> </p> <a href="https://publications.waset.org/abstracts/71190/effect-of-span-60-labrasol-and-cholesterol-on-labisia-pumila-loaded-niosomes-quality" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/71190.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">315</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); });*/ jQuery.get({ url: "https://publications.waset.org/xhr/user-menu", cache: false }).then(function(response){ jQuery('#mainNavMenu').append(response); }); }); </script> </body> </html>