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Stem Cells | Cell Biology | Tocris Bioscience

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Stem cells may be induced to form more specialized cells of a tissue or organ by a process termed cellular differentiation, which is defined by the potency of a cell.</p> <div class="tabbed_content"> <div class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="products" id="pharm_tabs_products"> <span>Targets</span></div> <div class="tab tab_4" data-tab="4" data-tabname="literature" id="pharm_tabs_literature"><span>Literature (4)</span> </div> <div class="tab tab_5" data-tab="5" data-tabname="pathways" id="pharm_tabs_pathways"><span>Pathways (3)</span> </div> </div> <div class="tab_content tab_1 tab_open" data-tab="1"> <div class="pharm_sub_cats"><h3>Stem Cell Target Files</h3><ul class="tile_column_1"><li><a href="/cell-biology/cancer-stem-cells" title="Browse products for Cancer Stem Cells">Cancer Stem Cells</a></li><li><a href="/cell-biology/cept-cocktail" title="Browse products for CEPT Cocktail">CEPT Cocktail</a></li><li><a href="/cell-biology/hematopoietic-stem-cells" title="Browse products for Hematopoietic Stem Cells (HSCs)">Hematopoietic Stem Cells (HSCs)</a></li><li><a href="/cell-biology/organoids" title="Browse products for Organoids">Organoids</a></li></ul><ul class="tile_column_2"><li><a href="/cell-biology/stem-cell-differentiation" title="Browse products for Stem Cell Differentiation">Stem Cell Differentiation</a></li><li><a href="/cell-biology/stem-cell-proliferation" title="Browse products for Stem Cell Proliferation">Stem Cell Proliferation</a></li><li><a href="/cell-biology/stem-cell-reprogramming" title="Browse products for Stem Cell Reprogramming">Stem Cell Reprogramming</a></li><li><a href="/cell-biology/stem-cell-signaling" title="Browse products for Stem Cell Signaling">Stem Cell Signaling</a></li></ul></div> <div class="pharm_rel_cats"><h3>Related Targets</h3><ul class="tile_column_1"><li><a href="/cell-biology/epigenetics" title="Browse products for Epigenetics">Epigenetics</a></li><li><a href="/product-type/gmp-ancillary-material-grade-small-molecules" title="Browse products for GMP &amp; Ancillary Material Grade Small Molecules">GMP &amp; Ancillary Material Grade Small Molecules</a></li><li><a href="/cell-biology/growth-factor-receptors" title="Browse products for Growth Factor Receptors">Growth Factor Receptors</a></li></ul><ul class="tile_column_2"><li><a href="/cell-biology/hedgehog-signaling" title="Browse products for Hedgehog Signaling">Hedgehog Signaling</a></li><li><a href="/product-type/viral-transduction-enhancers" title="Browse products for Viral Transduction Enhancers">Viral Transduction Enhancers</a></li><li><a href="/cell-biology/wnt-signaling" title="Browse products for Wnt Signaling">Wnt Signaling</a></li></ul></div> <div class="pharm_long_desc"><p>Owing to their regenerative potential, stem cells in some tissues and organs are utilized to repair or replace old or damaged cells and this property may be useful in regenerative medicine. In other tissues such as the heart, this does not occur and stem cells only divide under strict conditions.</p> <p>The four main types of stem cells are: embryonic stem cells (ESCs) found in the inner cell mass of blastocysts; adult (or somatic) stem cells, found in adult tissues and responsible for maintenance and repopulation of specific cell types; induced pluripotent stem cells (iPSCs), produced by the reprogramming of somatic cells; and cancer stem cells (CSCs).</p> <p>Stem cells offer the potential for treating many diseases including <a href='/research-area/cancer-research' title='Browse products for Cancer Research'>cancer</a> and neurodegenerative conditions, such as <a href='/research-area/parkinsons-disease-research' title='Browse products for Parkinson&#039;s Disease Research'>Parkinson&#039;s disease</a> or <a href='/research-area/huntingtons-disease-research' title='Browse products for Huntington&#039;s Disease Research'>Huntington&#039;s disease</a>, or nerve damage due to trauma.</p> <hr> <h3>Resources for Stem Cell Research</h3> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Blog Post: Regenerative Medicine - From Bench to Clinic</h4> <p>Regenerative medicine is the repair or replacement of damaged or diseased tissue to restore normal tissue function. This blog post discusses the development of a new cell therapy product derived from PSCs for regenerative medicine use in Parkinson&#039;s disease.</p> <a href='/resources/tocris-blog/regenerative-medicine-bench-clinic' title='Read Blog Post' class='btn btn-quinary'>Read Now!</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/tocris-blog/regenerative-medicine-bench-clinic' title='Read the Blog Post'><img src='https://resources.tocris.com/images/blog/regenerative-medicine-resources-bucket-image.jpg' alt='Regenerative Medicine - From Bench to Clinic'></a> </div> </div> <hr> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Stem Cell Protocols</h4> <p>Our protocol snapshots highlight how small molecules may be used in the stem cell workflow for maintenance, reprogramming and differentiation.</p> <a href='/resources/protocols/stem-cells' title='View stem cell protocols' class='btn btn-quinary'>Browse Protocols</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/protocols/stem-cells' title='View stem cell protocols'><img src='https://resources.tocris.com/images/targets/protocol-image-for-stem-cells-page.jpg' alt='Transdifferentiating Fibroblasts into Neurons Protocol'></a> </div> </div> <hr> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Blog post: Cerebral Organoids for Neurodevelopment, Neurodegeneration &amp; Virology Research</h4> <p>When derived from human cells, cerebral organoids enable the investigation of neurophysiology and disease using <em>in vitro</em> and <em>in vivo</em> methods that cannot be used in humans. This blog post describes how cerebral organoids can be used in neurodevelopment, neurodegeneration and virology research.</p> <a href='/resources/tocris-blog/cerebral-organoids-neurodevelopment-neurodegeneration-virology-research' title='Read Blog Post' class='btn btn-quinary'>Read Now!</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/tocris-blog/cerebral-organoids-neurodevelopment-neurodegeneration-virology-research' title='Read Blog Post'><img src='https://resources.tocris.com/images/blog/cerebral-organoids-blog-post-bucket.jpg' alt='Cerebral Organoids for Neurodevelopment, Neurodegeneration &amp; Virology Research'></a> </div> </div> <hr> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Blog Post: New Uses for Organoids</h4> <p>Organoids are stem cell-derived self-assembling 3D structures that are useful in advancing our understanding of the biology of complex systems. This blog post outlines the use of organoids in medicine and drug development.</p> <a href='/resources/tocris-blog/new-uses-organoids' title='Read the Blog Post' class='btn btn-quinary'>Read Now!</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/tocris-blog/new-uses-organoids' title='Read the Blog Post'><img src='https://resources.tocris.com/images/blog/organoids-blog-bucket-image.jpg' alt='New Uses for Organoids'></a> </div> </div> <hr> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Blog Post: Cryopreservation of Stem Cells with the ROCK Inhibitor</h4> <p>Cryopreservation for storage of cells is a key step in stem cell protocols. The ROCK inhibitor Y-27632 improves post-thaw survival rates. This blog post outlines how this compound protects stem cells from dissociated-associated apoptosis.</p> <a href='/resources/tocris-blog/rock-inhibitor-stem-cell-cryopreservation' title='Read the Blog Post' class='btn btn-quinary'>Read Now!</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/tocris-blog/rock-inhibitor-stem-cell-cryopreservation' title='Read the Blog Post'><img src='https://resources.tocris.com/images/blog/rock-inhibitor-bucket.png' alt='ROCK inhibitor for cryopreservation of stem cells'></a> </div> </div> <hr> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Blog Post: GMP Ancillary Materials for Stem Cell Therapy Manufacture</h4> <p>Stem cell therapies have the potential to treat several diseases, and these therapies are now entering clinical trials and approaching the clinic. This blog discusses small molecules as an ancillary material (AMs) for stem cell therapy manufacture, including their advantages over other types of AMs.</p> <a href='/resources/tocris-blog/gmp-ancillary-materials-importance-stem-cell-therapy-manufacture' title='Read the Blog Post' class='btn btn-quinary'>Read Now!</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/tocris-blog/gmp-ancillary-materials-importance-stem-cell-therapy-manufacture' title='Read the Blog Post'><img src='https://resources.tocris.com/images/blog/gmp-ancillary-materials-bucket.jpg' alt='Blog Post - GMP ancillary meterials for stem cell therapy manufacture'></a> </div> </div> <hr> <div class='row'> <div class='col-sm-12 col-md-6'> <h4>Blog Post: Small Molecules in Stem Cell Research</h4> <p>Small molecules are increasingly being used alone, or in combination with growth factors, to modulate stem cells. They can be used at all stages of the stem cell workflow, i.e. in reprogramming, maintenance, storage and differentiation protocols. This blog post outlines the advantages of using small molecules.</p> <a href='/resources/tocris-blog/five-reasons-use-small-molecules-stem-cell-research' title='Read the Blog Post' class='btn btn-quinary'>Read Now!</a> </div> <div class='col-sm-12 col-md-6 text-center'> <a href='/resources/tocris-blog/five-reasons-use-small-molecules-stem-cell-research' title='Read the Blog Post'><img src='https://resources.tocris.com/images/blog/small-molecules-for-stem-cells-bucket.jpg' alt='Five reasons to use small molecules in stem cell research'></a> </div> </div> <hr> <div class='pharm_rel_cats'> <h2>Related Product From Bio-Techne</h2> <ul class='tile_column_1'> <li><a href= 'https://www.bio-techne.com/p/cell-culture/excellerate-ipsc-expansion-medium-animal-free-gmp_ccm036-gmp' title='Find out more about GMP ExCellerate iPSC Expansion Medium' target='_blank'>GMP iPSC Expansion Medium</a></li> </ul> </div> <p>View all <a href='https://www.bio-techne.com/research-areas/ipsc' class='a___link-external' target='_blank' title='Visit bio-techne.com for more PSC resources'>pluripotent stem cell resources</a> available from Bio-Techne.</p></div> </div> <div class="tab_content tab_2" data-tab="2"> </div> <div class="tab_content tab_3" data-tab="3"> </div> <div class="tab_content tab_4" data-tab="4"> <h3>Literature for Stem Cells</h3><p>Tocris offers the following scientific literature for Stem Cells to showcase our products. We invite you to request* your copy today!</p><p class="small">*Please note that Tocris will only send literature to established scientific business / institute addresses.</p><hr/><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/product-guides/fullsize/683696.jpg?v=4" data-toggle="lightbox" data-title="Stem Cell Research Product Guide" data-footer="<a href='/literature/literature-request/683696' rel='nofollow' title='Request copy of the Stem Cell'>Request copy</a> or <a href='/literature/literature-request/p683696' rel='nofollow' title='Request PDF of the Stem Cell'>Request PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/product-guides/regular/683696.jpg?v=4" alt="Stem Cell Research Product Guide" class="img-fluid"></a></div><!-- /lit_image --> <h4>Stem Cell Research Product Guide</h4> <p>This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:</p> <ul class='bullet_list'> <li>Self-renewal and Maintenance</li> <li>Differentiation</li> <li>Reprogramming</li> <li>Organoid Generation</li> <li>GMP and Ancillary Material Grade Products </li> </ul> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/683696" rel="nofollow" title="Request copy of the Stem Cell Research Product Guide">Request copy</a> </li><li> <a class="btn btn-quinary request-pdf" href="/literature/literature-request/p683696" rel="nofollow" title="Request PDF of the Stem Cell Research Product Guide">Request PDF<div class="lit_request_pdf"></div></a> </li> <li><a class="btn btn-quinary" href="/literature/product-guides" title="View all Product Guides &amp; Listings">View all Product Guides &amp; Listings</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/reviews/fullsize/298320.jpg?v=2" data-toggle="lightbox" data-title="Stem Cells Scientific Review" data-footer="<a href='/literature/literature-request/298320' rel='nofollow' title='Request copy of the Stem Cells'>Request copy</a> or <a href='/literature/literature-request/p298320' rel='nofollow' title='Request PDF of the Stem Cells'>Request PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/reviews/regular/298320.jpg?v=2" alt="Stem Cells Scientific Review" class="img-fluid"></a></div><!-- /lit_image --> <h4>Stem Cells Scientific Review</h4> <p>Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.</p> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/298320" rel="nofollow" title="Request copy of the Stem Cells Scientific Review">Request copy</a> </li><li> <a class="btn btn-quinary request-pdf" href="/literature/literature-request/p298320" rel="nofollow" title="Request PDF of the Stem Cells Scientific Review">Request PDF<div class="lit_request_pdf"></div></a> </li> <li><a class="btn btn-quinary" href="/literature/scientific-reviews" title="View all Scientific Reviews">View all Scientific Reviews</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/630620.jpg" data-toggle="lightbox" data-title="Stem Cell Workflow Poster" data-footer="<a href='/literature/literature-request/630620' rel='nofollow' title='Request copy of the Stem Cell Workflow'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf' download='https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf' rel='nofollow' title='Download PDF of the Stem Cell Workflow' data-title='Stem Cell Workflow Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/630620.jpg" alt="Stem Cell Workflow Poster" class="img-fluid"></a></div><!-- /lit_image --> <h4>Stem Cell Workflow Poster</h4> <p>Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.</p> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/630620" rel="nofollow" title="Request copy of the Stem Cell Workflow Poster">Request copy</a> </li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cell Workflow Poster" data-title="Stem Cell Workflow Poster">Download PDF<div class="lit_pdf"></div></a></li> <li><a class="btn btn-quinary" href="/literature/life-science-posters" title="View all Life Science Posters">View all Life Science Posters</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/571184.jpg?v=2" data-toggle="lightbox" data-title="Stem Cells Poster" data-footer="<a href='/literature/literature-request/571184' rel='nofollow' title='Request copy of the Stem Cells'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf' download='https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf' rel='nofollow' title='Download PDF of the Stem Cells' data-title='Stem Cells Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/571184.jpg?v=2" alt="Stem Cells Poster" class="img-fluid"></a></div><!-- /lit_image --> <h4>Stem Cells Poster</h4> <p>Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.</p> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/571184" rel="nofollow" title="Request copy of the Stem Cells Poster">Request copy</a> </li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cells Poster" data-title="Stem Cells Poster">Download PDF<div class="lit_pdf"></div></a></li> <li><a class="btn btn-quinary" href="/literature/life-science-posters" title="View all Life Science Posters">View all Life Science Posters</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --> </div> <div class="tab_content tab_5" data-tab="5"> <h3>Pathways for Stem Cells</h3><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="/pathways/notch-signaling-pathway"><img loading="lazy" src="https://resources.tocris.com/images/literature/pathways/regular/304279.jpg" alt="Notch Signaling Pathway "></a></div><!-- /lit_image --> <h4><a href="/pathways/notch-signaling-pathway">Notch Signaling Pathway</a></h4> The Notch pathway is involved in determination of cell fate, regulation of pattern formation and other developmental settings. Disrupted signaling can cause developmental defects and a range of adult pathologies. <ul class="pb_lit_buttons"> <li><a class="btn btn-quinary" href="/pathways/notch-signaling-pathway" title="View Notch Signaling Pathway">View Pathway</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pathways/pdf/notch.pdf" download="https://resources.tocris.com/pathways/pdf/notch.pdf" rel="nofollow" target="_blank" title="Download PDF of the Notch Signaling Pathway" data-title="Notch Signaling Pathway">Download PDF</a></li> <li><a class="btn btn-quinary" href="/signaling-pathways" title="View all Pathways">View all Pathways</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="/pathways/tgf-beta-signaling-pathway"><img loading="lazy" src="https://resources.tocris.com/images/literature/pathways/regular/299050.jpg" alt="TGF-&#946; Signaling Pathway "></a></div><!-- /lit_image --> <h4><a href="/pathways/tgf-beta-signaling-pathway">TGF-&#946; Signaling Pathway</a></h4> The TGF-&#946; signaling pathway is involved in the regulation of growth and proliferation of cells along with migration, differentiation and apoptosis. <ul class="pb_lit_buttons"> <li><a class="btn btn-quinary" href="/pathways/tgf-beta-signaling-pathway" title="View TGF-&#946; Signaling Pathway">View Pathway</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pathways/pdf/tgfb.pdf" download="https://resources.tocris.com/pathways/pdf/tgfb.pdf" rel="nofollow" target="_blank" title="Download PDF of the TGF-&#946; Signaling Pathway" data-title="TGF-&#946; Signaling Pathway">Download PDF</a></li> <li><a class="btn btn-quinary" href="/signaling-pathways" title="View all Pathways">View all Pathways</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="/pathways/wnt-signaling-pathway"><img loading="lazy" src="https://resources.tocris.com/images/literature/pathways/regular/299054.jpg" alt="Wnt Signaling Pathway "></a></div><!-- /lit_image --> <h4><a href="/pathways/wnt-signaling-pathway">Wnt Signaling Pathway</a></h4> The Wnt pathway is involved in cellular differentiation and proliferation in adult tissues and also during embryogenesis. Disturbances within the pathway may lead to the formation of tumors and promote metastasis. <ul class="pb_lit_buttons"> <li><a class="btn btn-quinary" href="/pathways/wnt-signaling-pathway" title="View Wnt Signaling Pathway">View Pathway</a></li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pathways/pdf/wnt.pdf" download="https://resources.tocris.com/pathways/pdf/wnt.pdf" rel="nofollow" target="_blank" title="Download PDF of the Wnt Signaling Pathway" data-title="Wnt Signaling Pathway">Download PDF</a></li> <li><a class="btn btn-quinary" href="/signaling-pathways" title="View all Pathways">View all Pathways</a></li> </ul> </div><!-- /lit_content --></div><!-- /row --> </div> <div class="tab_content tab_6" data-tab="6"> </div> </div> </div> <div id="sidebar" class="col-xs-12 col-sm-4 col-md-3 col-lg-3 col-xl-3"> <div class="resources_sidebar_container"> <div class="fp_four_box"> <div class="fp_box_wrapper"><h3>Featured New Products</h3> <div class="fp_featured_product"><a href="/products/vu-0542270_8151">8151 | VU 0542270</a><br /> Selective inhibitor of K<sub>ir</sub>6.1 K<sub>ATP</sub> channels</div> <div class="fp_featured_product"><a href="/products/rna-imaging-probe-1c_8813">8813 | RNA Imaging Probe 1c</a><br /> Fluorogenic RNA imaging probe</div> <div class="fp_featured_product"><a href="/products/lsn-3318839_7959">7959 | LSN 3318839</a><br /> Glucagon-like peptide-1 receptor <br />(GLP1-R) positive allosteric modulator</div> <div class="fp_featured_product"><a href="/products/chir-99021-in-solution_8170">8170 | CHIR 99021 in solution</a><br /> Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO</div> <div class="fp_featured_product"><a href="/products/bi-3231_8039">8039 | BI 3231</a><br /> Potent and selective hydroxysteroid 17尾 dehydrogenase 13 (HSD17B13) inhibitor</div> </div> </div> </div> <div class="distributor_region"></div> <div class="widget"> <div class="widget_title">Literature in this Area</div> <div class="widget_content carousel slide" id="ds_literature_scroller" data-ride="carousel" data-interval="8000"> <!-- Carousel Slides --> <div class="carousel-inner"><div class="item active"><div class="highlight">Stem Cell Research Product Guide</div> <a href="/literature/product-guides/stem-cell"><img loading="lazy" src="https://resources.tocris.com/images/literature/product-guides/regular/683696.jpg?v=4" alt="Stem Cell Research Product Guide"></a><p class="small">Our guide highlights the use of small molecules in stem cell research and cell therapy and lists relevant products.</p><a class="btn btn-quinary" href="/literature/literature-request/683696" rel="nofollow" title="Request copy of the Stem Cell Research Product Guide">Request copy</a><a class="btn btn-quinary request-pdf" href="/literature/literature-request/p683696" rel="nofollow" title="Request PDF of the Stem Cell Research Product Guide">Request PDF<div class="lit_request_pdf"></div></a></div><div class="item"><div class="highlight">Stem Cells Scientific Review</div> <a href="/literature/scientific-reviews/stem-cells"><img loading="lazy" src="https://resources.tocris.com/images/literature/reviews/regular/298320.jpg?v=2" alt="Stem Cells Scientific Review"></a><p class="small">Our Stem Cells review gives an overview of the use of small molecules in the control of stem cell growth &amp; differentiation and somatic cell reprogramming.</p><a class="btn btn-quinary" href="/literature/literature-request/298320" rel="nofollow" title="Request copy of the Stem Cells Scientific Review">Request copy</a><a class="btn btn-quinary request-pdf" href="/literature/literature-request/p298320" rel="nofollow" title="Request PDF of the Stem Cells Scientific Review">Request PDF<div class="lit_request_pdf"></div></a></div><div class="item"><div class="highlight">Stem Cell Workflow Life Science Poster</div> <a href="/literature/life-science-posters/stem-cell-workflow"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/630620.jpg" alt="Stem Cell Workflow Poster"></a><p class="small">Developed in-house, this poster summarizes how small molecules have been used in protocols across the stem cell workflow.</p><a class="btn btn-quinary" href="/literature/literature-request/630620" rel="nofollow" title="Request copy of the Stem Cell Workflow Poster">Request copy</a><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cell Workflow Poster" data-title="Stem Cell Workflow Poster">Download PDF<div class="lit_pdf"></div></a></div><div class="item"><div class="highlight">Stem Cells Life Science Poster</div> <a href="/literature/life-science-posters/stem-cells"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/571184.jpg?v=2" alt="Stem Cells Poster"></a><p class="small">Written by Rebecca Quelch and Stefan Przyborski, this poster summarizes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and potential uses.</p><a class="btn btn-quinary" href="/literature/literature-request/571184" rel="nofollow" title="Request copy of the Stem Cells Poster">Request copy</a><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cells Poster" data-title="Stem Cells Poster">Download PDF<div class="lit_pdf"></div></a></div></div> <!-- Controls --> <a class="left carousel-control" href="#ds_literature_scroller" role="button" data-slide="prev"> <span class="icon-prev" aria-hidden="true"></span> <span class="sr-only">Previous</span> </a> <a class="right carousel-control" href="#ds_literature_scroller" role="button" data-slide="next"> <span class="icon-next" aria-hidden="true"></span> <span class="sr-only">Next</span> </a> </div> </div> </div> </section> <section id="block-block-16" class="block block-block clearfix"> <!-- Start of Invitations --> <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true" style="display: none;"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" aria-describedby="snapins_bodytext" style="height:48px;"> <img id="embeddedServiceAvatar" /> <span class="embeddedServiceTitleText" id="snapins_titletext">Need help?</span> <button type="button" id="closeInvite" class="embeddedServiceCloseIcon" aria-label="Exit invitation">&times;</button> </div> <div class="embeddedServiceInvitationBody"> <p id="snapins_bodytext">How can we help you?</p> </div> <div class="embeddedServiceInvitationFooter" aria-describedby="snapins_bodytext"> <button type="button" class="embeddedServiceActionButton" id="rejectInvite">Close</button> <button type="button" class="embeddedServiceActionButton" id="acceptInvite">Start Chat</button> </div> </div> </section> </div> </div> </div> <footer id="footer_wrapper" class="container-fluid"> <div id="footer_wrapper_container" class="row"> <div id="footer" class="container"> <div id="footer_container" class="row"> <nav class="footer_column footer_column_1 col-xs-12 col-sm-3"> <div class="region region-footer-column-1"> <section id="block-menu-menu-corporate-menu" class="block block-menu clearfix"> <h6 class="block-title">Corporate</h6> <ul class="menu nav"><li class="first leaf"><a href="/about-tocris" id="menu-corporate-menu-14021">About Us</a></li> <li class="leaf"><a href="/about-tocris/careers-at-tocris" id="menu-corporate-menu-14026">Careers</a></li> <li class="leaf"><a href="/about-tocris/tocris-events" id="menu-corporate-menu-14031">Events</a></li> <li class="leaf"><a href="/support/terms-and-conditions-of-sale" id="menu-corporate-menu-591">Terms &amp; 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