Whole Genome Sequencing | GENEWIZ from Azenta

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href='/en/Public/Services/Next-Generation-Sequencing/Standalone-NGS-Solutions' style='color:#585F69;font-size:14px'>Sequencing Only<br></a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Whole-Genome-Sequencing' style='color:#585F69;font-size:14px'>Whole Genome Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/High-Throughput-Genotyping' style='color:#585F69;font-size:14px'>CRISPR Validation</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Targeted-Resequencing-Panels' style='color:#585F69;font-size:14px'>Targeted Sequencing</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Metagenomics-Solutions' style='color:#585F69;font-size:14px'>Metagenomics </a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Epigenomics' style='color:#585F69;font-size:14px'>Epigenomics</a></li><li><a href='/en/Public/Services/Next-Generation-Sequencing/Antibody-Discovery' 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Walking</a></li><br><li><a class='GColor' href='/en/Public/Services/Molecular-Genetics' style='color:#826ec3;font-size:17px'>PCR + Sanger Services</a></li><li><a href='/en/Public/Services/Molecular-Genetics/Bacterial-and-Fungal-Identification' style='color:#585F69;font-size:14px'>Bacterial and Fungal Identification</a></li><li><a href='/en/Public/Services/Molecular-Genetics/Mutation-Analysis' style='color:#585F69;font-size:14px'>Mutation Analysis</a></li><li><a href='/en/Public/Services/Molecular-Genetics/SNP-Genotyping' style='color:#585F69;font-size:14px'>SNP Genotyping</a></li><li><a href='/en/Public/Services/Molecular-Genetics/PCR-Plus-Sequencing-CRISPR-Analysis-Package' style='color:#585F69;font-size:14px'>PCR Plus Sequencing CRISPR Analysis Package</a></li><li><a href='/en/Public/Services/Molecular-Genetics/cDNA-Verification' style='color:#585F69;font-size:14px'>Confirmatory Sequencing & Cell Bank Characterization</a></li><li><a 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Whole Genome Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/Regulatory' style='color:#585F69;font-size:14px'>GLP-Compliant Overview</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-Confirmatory-Sequencing' style='color:#585F69;font-size:14px'>GLP Confirmatory Sequencing</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-SNP-Mutation-Analysis' style='color:#585F69;font-size:14px'>GLP SNP Mutation Analysis</a></li><li><a href='/en/Public/Services/Clinical-Services/GLP-compliant-Plasmid-Prep' style='color:#585F69;font-size:14px'>GLP Plasmid Prep</a></li><li><a href='/en/Public/Services/Clinical-Services/Nucleic-Acid-Extraction' style='color:#585F69;font-size:14px'>GLP Nucleic Acid Extraction</a></li><li><a href='/en/Public/Services/Clinical-Services/Biofluid-Processing-Overview' style='color:#585F69;font-size:14px'>Biofluid Processing</a></li><li><a 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Extraction through data analysis is available.</p> </div> </div> <div class="wgs-service" id="wgs-service-3"> <div class="wgs-service-content"> <h3>Long-Read Whole Genome Sequencing</h3> <br> <p>Long-read sequencing on the PacBio® Sequel® delivers up to 60 kb reads with contig N50 > 1 Mb. Generate reference quality assemblies for prokaryotic genomes. Ideal for structural variant calling in eukaryotes.</p> </div> </div> <div class="wgs-service" id="wgs-service-5"> <div class="wgs-service-content"> <h3>Low-Pass Whole Genome Sequencing</h3> <br> <p>Accurately detect genetic variation throughout genomes of a multitude of species. Achieve up to 99% accuracy of variant call detection at a very low sequence coverage (0.1X<10X) using imputation algorithms.</p> <p> </p> <p> </p> </div> <a rel="noopener noreferrer" href="https://www.genewiz.com/en/Public/Services/Next-Generation-Sequencing/Low-Pass-WholeGenomeSequencing"><button class="wgs-service-btn">Learn More</button></a> </div> <div class="wgs-service" id="wgs-service-6"> <div class="wgs-service-content"> </div> </div> </div> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .question { width: 1170px; display: inline-block; } .question p { width: 90%; text-align: left; } .question ul { width: 90%; text-align: left; } @media screen and (max-width: 1170px) { .question { width: auto; } } </style> <div class="question"> <h2>What is whole genome sequencing and what is it used for?</h2> <p>Whole genome sequencing (WGS) is the comprehensive read and analysis of an entire genome, including non-coding regions of the genome.</p> <p>WGS is used to facilitate discovery of novel genes and gene variants associated with disease. In the case of human WGS, researchers use WGS to explore gene expression and functional elements of the genome that help predict an individual’s response to drug therapies. WGS is also used to study the evolution of infectious pathogens and mechanisms of disease-causing mutation. Find the right NGS solution for your project using our <a href="https://www.genewiz.com/en/Public/Services/Next-Generation-Sequencing">interactive guide</a>.</p> <p> </p> </div> </div> <div class="headline-center Rich-Text-Edit-Area"> <style type="text/css"> .body1 { text-align: center; display: inline-block; } .banner-background1 { width: 1170px; background-image: url('/-/media/13070-D_NGS-Platforms_WebBanFull-Lrg_Background.ashx'); background-size: cover; text-align: center; display: flex; padding: 10px; } .banner img1 { text-align: center; display: block; margin-left: auto; margin-right: auto; } #banner-left1 { width: 40%; padding: 30px; } #banner-right1 { width: 59%; padding: 30px; } #banner-right1 h2 { text-transform: none; letter-spacing: 1px; line-height: 40px; border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 40px; margin: 0; margin-bottom: 0px; color: #FFFFFF; } #banner-right1 h3 { text-transform: none; letter-spacing: 1px; line-height: 50px; 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border-bottom: none; font-family: 'Roboto', sans-serif; font-weight: 400; font-size: 30px; margin: 0; margin-bottom: 15px; color: #FFFFFF; } #banner-left1 img { width: auto; height: auto; } #banner-right1 img { width: 90%; height: auto; } @media only screen and (max-width: 700px) { #banner-left1 img { width: 60%; } #banner-right1 button { font-size: 14px; } } </style> <div class="body1"> <div class="banner-background1"> <div id="banner-left1"> <img alt="" src="/-/media/13070-D_NGS-Platforms_WebBanFull-Lrg_Thumbnail.ashx?la=en&hash=2267956154B8A11D571A104DAF0356024C1845F7" /> </div> <div id="banner-right1"> <div id="banner-right1 h2"> <h3></h3> <h2>Take advantage of the latest long-read and short-read sequencing technology to accelerate your research</h2> <div id="banner-right1 h3"> <h3 style="color:#FFFFFF;"></h3> <br /> <a rel="noopener noreferrer" rel="noopener noreferrer" href="https://www.genewiz.com/en/Public/Resources/NGS-Platforms" target="_blank"><button>LEARN MORE</button></a> </div> </div> </div> </div> </div> </div> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Gray margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0 "> <div class=" container"> <div class="headline-center"> <br /> <h2>WGS coverage for any application</h2> <p></p> </div> <ul class="list-unstyled row "> <li class='col-sm-4'> <a href='https://web.genewiz.com/low-pass-wgs-quote-request ' target=''> <div class='SingleIcon headline-center Component-BackGround-Gray margin-top-0 padding-top-0 '> <div class="row"> <img src="/-/media/Images/Icon_210x110_10xcoverage.ashx?h=111&la=en&w=210&hash=F0EF744DB897143BC2031B78493FB3E385DD49AF" alt="Building" width="210" height="111" /> </div> <div class="row"> <br><strong><10x Coverage</strong><br> (Shallow or Low-pass) </div> <div class="row"> Structural variant discovery<br> Population screening<br><br> </div> </div> </a> </li>  <li class='col-sm-4'> <a href='/en/Public/Services/Next-Generation-Sequencing/Whole-Genome-Sequencing' target=''> <div class='SingleIcon headline-center Component-BackGround-Gray margin-top-0 padding-top-10 '> <div class="row"> <img src="/-/media/Images/Icon_210x110_30xcoverage.ashx?h=111&la=en&w=211&hash=6AC9A692C634100188F9DCCDB353CBDA4AA72DD2" alt="Building" width="211" height="111" /> </div> <div class="row"> <br> <strong>30x Coverage<br></strong> <br> </div> <div class="row"> Germline variant analysis </div> </div> </a> </li>  <li class='col-sm-4'> <a href='/en/Public/Services/Next-Generation-Sequencing/Whole-Genome-Sequencing' target=''> <div class='SingleIcon headline-center Component-BackGround-Gray margin-top-0 padding-top-10 '> <div class="row"> <img src="/-/media/Images/Icon_210x110_100xcoverage.ashx?h=111&la=en&w=211&hash=AFAB50A25603F2801BAB5E516F2572141DA92AA7" alt="Building" width="211" height="111" /> </div> <div class="row"> <br /><strong>≥100x coverage</strong><br /> (Ultra-deep) </div> <div class="row"> <em>De novo</em> assembly<br> Somatic/rare mutation discovery<br><br> </div> </div> </a> </li>  </ul> <div class="row headline-center"> </div> </div> </div><script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".SingleIcon").find("img").addClass("img-responsive center-block"); }); </script> <div class="process-v1 icon-nav Component-BackGround-Default margin-top-0 margin-bottom-0 padding-top-10 padding-bottom-0"> <div class="container"> <div class="headline-center"> <br> <h2>Features & Benefits</h2> <p></p> </div> <ul class="list-unstyled row "> <li class='col-sm-4'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 padding-top-10 '> <div class="row"> <img src="/-/media/Images/Icon_210x110_DataQuality.ashx?h=111&la=en&w=210&hash=F46A139E13601092EDFE15C700991941F32C09B1" alt="Building" width="210" height="111" /> </div> <div class="row"> <br /><strong>Superior Data Quality</strong> </div> <div class="row"> Exceeding manufacturer’s benchmarks </div> </div> </li>  <li class='col-sm-4'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 padding-top-10 '> <div class="row"> <img src="/-/media/Images/Icon_210x110_FastTurnaround.ashx?h=111&la=en&w=211&hash=9A3DD65E2E3F8FEA60D325EE4EAAE1448F0A500D" alt="Building" width="211" height="111" /> </div> <div class="row"> <br /><strong>Fast Turnaround</strong> </div> <div class="row"> Starting at 1 week for sequencing </div> </div> </li>  <li class='col-sm-4'> <div class='SingleIcon headline-center Component-BackGround-Defaultmargin-top-0 padding-top-10 '> <div class="row"> <img src="/-/media/Images/Icon_210x110_US-Based.ashx?h=111&la=en&w=211&hash=CFBC4304C173B0F6800FA89963A50246931F94D2" alt="Building" width="211" height="111" /> </div> <div class="row"> <br /><strong>US-Based Processing</strong> </div> <div class="row"> Sequencing and customer support in New Jersey </div> </div> </li>  </ul> <div class="row headline-center"> </div> </div> </div><script type="text/javascript" src="/assets/plugins/counter/jquery.counterup.min.js"></script> <script language="javascript" type="text/javascript"> jQuery(document).ready(function ($) { $(".row .category").find("img").addClass("img-responsive"); 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} } @media only screen and (max-width: 1170px) { .tech-resources-container { width: 80%; margin: 0 auto; } } </style> <div class="tech-resources-main"> <div class="tech-resources-container"> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/13040_BI-Workbook_WE-Thumbnail.ashx?la=en&hash=9367D8BE069ABFF205E77EAD00B7F5EC91CC0BB2"> </div> <div class="resource resource-right"> <h3>Quick Start Guide | Exploring Bioinformatics for Genome and Transcriptome Sequencing Data</h3> <p>For those new to bioinformatics, analyzing massive amounts of NGS data can be a daunting task. Download Azenta’s bioinformatics quick start guide to learn how to analyze whole genome sequencing (WGS) and RNA sequencing (RNA-Seq) data with bioinformatics tools to reveal biological insights for your research. <br> <a href="https://hubs.ly/Q01lHpqz0" target="_blank"> <button>Download Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13044_Pacbio_CaseStudy-Thumb.ashx?la=en&hash=4F711AC3D55EC1B10FFD00FBC7529820D8B3BD15"> </div> <div class="resource resource-right"> <h3>Case Study | Detection of Previously Unidentified Structural Variants Involved in Glioblastoma Using PacBio<sup>®</sup> Sequel<sup>®</sup> Sequencing</h3> <p>This case study looks at how Azenta utilized the PacBio Sequel long-read technology to help a customer improve detection of structural variants within glioblastoma samples. <br> <a href="https://web.genewiz.com/case-study/pacbio-sequel-structural-variants-glioblastoma" target="_blank"> <button>Download</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/73025-D_Pacbio_Webinar.ashx?la=en&hash=20178B9BBF290DD1BD099C42CE32B5069D773BFD"> </div> <div class="resource resource-right"> <h3>Webinar | A New Paradigm in DNA Sequencing – Highly Accurate Single-Molecule Long Reads (Hosted by PacBio)</h3> <p>In this PacBio-hosted webinar, Jonas Korlach, PacBio Chief Scientific Officer, and Dave Corney, Azenta Associate Principal Scientist, Next Generation Sequencing, describe the recent release of Sequel System 6.0, which has revolutionized long-read sequencing by providing users the ability to generate highly accurate single-molecule reads. <br> <a href="https://web.genewiz.com/pacbio-new-paradigm" target="_blank"> <button>Watch Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13049_Pacbio_TechNote-Thumb.ashx?la=en&hash=72D68DC657B9E2AC8F416CD12A40384B6B66152B" width="220"> </div> <div class="resource resource-right"> <h3>Tech Note | Multiplexing Microbes on the PacBio Sequel: Feasibility, Benefits, and Recent Developments</h3> <p>This study proves the feasibility of multiplexing and highlights the key advantages of the PacBio Sequel platform as compared to its predecessor, the RSII. <br> <a href="https://web.genewiz.com/tech-note/multiplexing-microbes-pacbio-sequel" target="_blank"> <button>Download</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13013_DNA-Prep_Best-Practices-Thumb.ashx?la=en&hash=563C571C2F8D20ADC158DF6EF9434872992BC715"> </div> <div class="resource resource-right"> <h3>Best Practices | Preparation of High Molecular Weight DNA</h3> <p>High-quality high molecular weight (HMW) genomic DNA (≥50 kb) is critical to achieving long read lengths on platforms such as the 10x Genomics<sup>®</sup> Chromium™ and the PacBio Sequel. Follow these guidelines to generate the best possible WGS results. <br> <a href="https://cdn2.hubspot.net/hubfs/3478602/NGS/Whole Genome Sequencing/Best Practices HMW DNA.pdf" target="_blank"> <button>Download</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13037_100-Genome_Webinar-Thumb.ashx?la=en&hash=2FF09FA27EA796A7170610FBEE0D33813BE05359"> </div> <div class="resource resource-right"> <h3>The $100 Genome: Using Low-Pass Whole Genome Sequencing as an Alternative to Genotyping Arrays</h3> <p>In this webinar originally presented at the ASHG 2020 Virtual Meeting, learn how low-pass WGS overcomes the inherent limitations and biases of traditional arrays, offering an inexpensive, high-throughput alternative for detecting genome-wide genetic variation and novel variants. <br> <a href="https://web.genewiz.com/the-100-genome-register" target="_blank"> <button>Watch Now</button> </a> </p> </div> </div> <div class="tech-resource"> <div class="resource resource-left"> <img alt="" src="/-/media/Images/13024DWGSWorkshopUSEUWebTechThumb.ashx?la=en&hash=454D6CE4B90623F7029E28704844B65F6E22ACD8"> </div> <div class="resource resource-right"> <h3>Workshop & Roundtable Discussion | Exploring Bioinformatics for Whole Genome Sequencing (WGS) Data</h3> <p>In this recording of our WGS bioinformatics workshop & roundtable discussion led by bioinformatics scientist Zain Alvi, Ph.D., we'll guide you through the WGS bioinformatics process to help you learn to interpret WGS bioinformatics results, as well as address common challenges and answer frequently asked questions (FAQs). <br> <a href="https://web.azenta.com/wgs-data-bi-workshop?utm_campaign=BI Training Workshop 2022&utm_source=wgs&utm_medium=technical resources&utm_content=us&__hstc=251210969.ee677d8374177d47808d4f65f2e7a318.1652957843001.1665665595413.1665734959473.204&__hssc=251210969.37.1665734959473&__hsfp=1345237511" target="_blank"> 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