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Search results for: Shlomo Kaniel
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class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Shlomo Kaniel"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 10</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Shlomo Kaniel</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Adjustment of Parents of Children with Autism: A Multivariate Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ayelet%20Siman-Tov">Ayelet Siman-Tov</a>, <a href="https://publications.waset.org/abstracts/search?q=Shlomo%20Kaniel"> Shlomo Kaniel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The research validates a multivariate model that predicts parental adjustment to coping successfully with an autistic child. The model comprises four elements: parental stress, parental resources, parental adjustment and the child's autism symptoms. Background and aims: The purpose of the current study is the construction and validation of a model for the adjustment of parents and a child with autism. The suggested model is based on theoretical views on stress and links personal resources, stress, perception, parental mental health and quality of marriage and child adjustment with autism. The family stress approach focuses on the family as a system made up of a dynamic interaction between its members, who constitute interdependent parts of the system, and thus, a change in one family member brings about changes in the processes of the entire family system. From this perspective, a rise of new demands in the family and stress in the role of one family member affects the family system as a whole. Materials and methods: 176 parents of children aged between 6 to 16 diagnosed with ASD answered several questionnaires measuring parental stress, personal resources (sense of coherence, locus of control, social support), adjustment (mental health and marriage quality) and the child's autism symptoms. Results: Path analysis showed that a sense of coherence, internal locus of control, social support and quality of marriage increase the ability to cope with the stress of parenting an autistic child. Directions for further research are suggested. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress" title="stress">stress</a>, <a href="https://publications.waset.org/abstracts/search?q=adjustment" title=" adjustment"> adjustment</a>, <a href="https://publications.waset.org/abstracts/search?q=resources" title=" resources"> resources</a>, <a href="https://publications.waset.org/abstracts/search?q=Autism" title=" Autism"> Autism</a>, <a href="https://publications.waset.org/abstracts/search?q=parents" title=" parents"> parents</a>, <a href="https://publications.waset.org/abstracts/search?q=coherence" title=" coherence"> coherence</a> </p> <a href="https://publications.waset.org/abstracts/160464/adjustment-of-parents-of-children-with-autism-a-multivariate-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/160464.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> The Coexistence of Quality Practices and Frozen Concept in R and D Projects</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ayala%20Kobo-Greenhut">Ayala Kobo-Greenhut</a>, <a href="https://publications.waset.org/abstracts/search?q=Amos%20Notea"> Amos Notea</a>, <a href="https://publications.waset.org/abstracts/search?q=Izhar%20Ben-Shlomo"> Izhar Ben-Shlomo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In R&D projects, there is no doubt about the need to change a current concept to an alternative one over time (i.e., concept leaping). Concept leaping is required since with most R&D projects uncertainty is present as they take place in dynamic environments. Despite the importance of concept leaping when needed, R&D teams may fail to do so (i.e., frozen concept). This research suggests a possible reason why frozen concept happens in the framework of quality engineering and control engineering. We suggest that frozen concept occurs since concept determines the derived plan and its implementation may be considered as equivalent to a closed-loop process, and is subject to the problem of not recognizing gaps as failures. We suggest that although implementing quality practices into an R&D project’s routine has many advantages, it intensifies the frozen concept problem since working according to quality practices relates to exploitation of learning behavior, while leaping to a new concept relates to exploring learning behavior. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=closed%20loop" title="closed loop">closed loop</a>, <a href="https://publications.waset.org/abstracts/search?q=control%20engineering" title=" control engineering"> control engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=design" title=" design"> design</a>, <a href="https://publications.waset.org/abstracts/search?q=leaping" title=" leaping"> leaping</a>, <a href="https://publications.waset.org/abstracts/search?q=frozen%20concept" title=" frozen concept"> frozen concept</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20engineering" title=" quality engineering"> quality engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20practices" title=" quality practices"> quality practices</a> </p> <a href="https://publications.waset.org/abstracts/24806/the-coexistence-of-quality-practices-and-frozen-concept-in-r-and-d-projects" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24806.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">472</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Image Retrieval Based on Multi-Feature Fusion for Heterogeneous Image Databases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20W.%20U.%20D.%20Chathurani">N. W. U. D. Chathurani</a>, <a href="https://publications.waset.org/abstracts/search?q=Shlomo%20Geva"> Shlomo Geva</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinod%20Chandran"> Vinod Chandran</a>, <a href="https://publications.waset.org/abstracts/search?q=Proboda%20Rajapaksha"> Proboda Rajapaksha </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Selecting an appropriate image representation is the most important factor in implementing an effective Content-Based Image Retrieval (CBIR) system. This paper presents a multi-feature fusion approach for efficient CBIR, based on the distance distribution of features and relative feature weights at the time of query processing. It is a simple yet effective approach, which is free from the effect of features' dimensions, ranges, internal feature normalization and the distance measure. This approach can easily be adopted in any feature combination to improve retrieval quality. The proposed approach is empirically evaluated using two benchmark datasets for image classification (a subset of the Corel dataset and Oliva and Torralba) and compared with existing approaches. The performance of the proposed approach is confirmed with the significantly improved performance in comparison with the independently evaluated baseline of the previously proposed feature fusion approaches. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=feature%20fusion" title="feature fusion">feature fusion</a>, <a href="https://publications.waset.org/abstracts/search?q=image%20retrieval" title=" image retrieval"> image retrieval</a>, <a href="https://publications.waset.org/abstracts/search?q=membership%20function" title=" membership function"> membership function</a>, <a href="https://publications.waset.org/abstracts/search?q=normalization" title=" normalization"> normalization</a> </p> <a href="https://publications.waset.org/abstracts/52968/image-retrieval-based-on-multi-feature-fusion-for-heterogeneous-image-databases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52968.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">345</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Data Privacy: Stakeholders’ Conflicts in Medical Internet of Things</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Benny%20Sand">Benny Sand</a>, <a href="https://publications.waset.org/abstracts/search?q=Yotam%20Lurie"> Yotam Lurie</a>, <a href="https://publications.waset.org/abstracts/search?q=Shlomo%20Mark"> Shlomo Mark</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Medical Internet of Things (MIoT), AI, and data privacy are linked forever in a gordian knot. This paper explores the conflicts of interests between the stakeholders regarding data privacy in the MIoT arena. While patients are at home during healthcare hospitalization, MIoT can play a significant role in improving the health of large parts of the population by providing medical teams with tools for collecting data, monitoring patients’ health parameters, and even enabling remote treatment. While the amount of data handled by MIoT devices grows exponentially, different stakeholders have conflicting understandings and concerns regarding this data. The findings of the research indicate that medical teams are not concerned by the violation of data privacy rights of the patients' in-home healthcare, while patients are more troubled and, in many cases, are unaware that their data is being used without their consent. MIoT technology is in its early phases, and hence a mixed qualitative and quantitative research approach will be used, which will include case studies and questionnaires in order to explore this issue and provide alternative solutions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MIoT" title="MIoT">MIoT</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20privacy" title=" data privacy"> data privacy</a>, <a href="https://publications.waset.org/abstracts/search?q=stakeholders" title=" stakeholders"> stakeholders</a>, <a href="https://publications.waset.org/abstracts/search?q=home%20healthcare" title=" home healthcare"> home healthcare</a>, <a href="https://publications.waset.org/abstracts/search?q=information%20privacy" title=" information privacy"> information privacy</a>, <a href="https://publications.waset.org/abstracts/search?q=AI" title=" AI"> AI</a> </p> <a href="https://publications.waset.org/abstracts/153239/data-privacy-stakeholders-conflicts-in-medical-internet-of-things" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/153239.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">102</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Rechargable N-Halamine Nanoparticles for Antibacterial and Antifouling Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michal%20%20Natan">Michal Natan</a>, <a href="https://publications.waset.org/abstracts/search?q=Ori%20Gutman"> Ori Gutman</a>, <a href="https://publications.waset.org/abstracts/search?q=Shlomo%20Margel"> Shlomo Margel</a>, <a href="https://publications.waset.org/abstracts/search?q=Ehud%20%20Banin"> Ehud Banin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biofilm formation is a serious problem in medical and industrial settings due to the increased resistance of these communities to killing compared to free-living bacteria. This has prompted the search for agents that can inhibit both bacterial growth and biofilm formation. In this study, N-halamine rechargeable nanoparticles (NPs) were synthesized by co-polymerization of the monomer methacryl amide and the cross-linker monomer N,N-methylene bisacryl amide, and were subsequently loaded with Cl+, using bleach. The chlorinated NPs exhibited remarkable stability to organic reagents. The antibacterial mechanism of the P(MAA-MBAA)-Cl NPs involved generation of reactive oxygen species (ROS) only upon exposure to organic media, but not upon incubation in water, suggesting a specific activation. Moreover, a unique interaction of the P(MAA-MBAA)-Cl NPs with Staphylococcus aureus bacteria but not with human cells was discovered, whereby these microorganisms were all specifically targeted and marked for destruction. Finally, in collaboration with Netafim Ltd. irrigation drippers containing the P(MAA-MBAA)-Cl were incubated in the field and were shown to prevent fouling on them for 5 months as opposed to the control drippers that exhibited substantial fouling. Further, the NPs offer recharging to the surface, thus providing long-lasting protection that does not exist in the products available today. Taken together, the results demonstrate the great potential of implementing the charged NPs in devices and surfaces to prevent bacterial growth. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bacteria" title="bacteria">bacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=biofilm" title=" biofilm"> biofilm</a>, <a href="https://publications.waset.org/abstracts/search?q=fouling" title=" fouling"> fouling</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/64606/rechargable-n-halamine-nanoparticles-for-antibacterial-and-antifouling-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64606.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">198</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> AI Ethical Values as Dependent on the Role and Perspective of the Ethical AI Code Founder- A Mapping Review</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Moshe%20Davidian">Moshe Davidian</a>, <a href="https://publications.waset.org/abstracts/search?q=Shlomo%20Mark"> Shlomo Mark</a>, <a href="https://publications.waset.org/abstracts/search?q=Yotam%20Lurie"> Yotam Lurie</a> </p> <p class="card-text"><strong>Abstract:</strong></p> With the rapid development of technology and the concomitant growth in the capability of Artificial Intelligence (AI) systems and their power, the ethical challenges involved in these systems are also evolving and increasing. In recent years, various organizations, including governments, international institutions, professional societies, civic organizations, and commercial companies, have been choosing to address these various challenges by publishing ethical codes for AI systems. However, despite the apparent agreement that AI should be “ethical,” there is debate about the definition of “ethical artificial intelligence.” This study investigates the various AI ethical codes and their key ethical values. From the vast collection of codes that exist, it analyzes and compares 25 ethical codes that were found to be representative of different types of organizations. In addition, as part of its literature review, the study overviews data collected in three recent reviews of AI codes. The results of the analyses demonstrate a convergence around seven key ethical values. However, the key finding is that the different AI ethical codes eventually reflect the type of organization that designed the code; i.e., the organizations’ role as regulator, user, or developer affects the view of what ethical AI is. The results show a relationship between the organization’s role and the dominant values in its code. The main contribution of this study is the development of a list of the key values for all AI systems and specific values that need to impact the development and design of AI systems, but also allowing for differences according to the organization for which the system is being developed. This will allow an analysis of AI values in relation to stakeholders. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20intelligence" title="artificial intelligence">artificial intelligence</a>, <a href="https://publications.waset.org/abstracts/search?q=ethical%20codes" title=" ethical codes"> ethical codes</a>, <a href="https://publications.waset.org/abstracts/search?q=principles" title=" principles"> principles</a>, <a href="https://publications.waset.org/abstracts/search?q=values" title=" values"> values</a> </p> <a href="https://publications.waset.org/abstracts/161826/ai-ethical-values-as-dependent-on-the-role-and-perspective-of-the-ethical-ai-code-founder-a-mapping-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161826.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">107</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> The Effect of Filter Cake Powder on Soil Stability Enhancement in Active Sand Dunes, In the Long and Short Term</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Irit%20Rutman%20Halili">Irit Rutman Halili</a>, <a href="https://publications.waset.org/abstracts/search?q=Tehila%20Zvulun"> Tehila Zvulun</a>, <a href="https://publications.waset.org/abstracts/search?q=Natali%20%20Elgabsi"> Natali Elgabsi</a>, <a href="https://publications.waset.org/abstracts/search?q=Revaya%20Cohen"> Revaya Cohen</a>, <a href="https://publications.waset.org/abstracts/search?q=Shlomo%20Sarig"> Shlomo Sarig</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Active sand dunes (ASD) may cause significant damage to field crops and livelihood, and therefore, it is necessary to find a treatment that would enhance ADS soil stability. Biological soil crusts (biocrusts) contain microorganisms on the soil surface. Metabolic polysaccharides secreted by biocrust cyanobacteria glue the soil particles into aggregates, thereby stabilizing the soil surface. Filter cake powder (FCP) is a waste by-product in the final stages of the production of sugar from sugarcane, and its disposal causes significant environmental pollution. FCP contains high concentrations of polysaccharides and has recently been shown to be soil stability enhancing agent in ASD. It has been reported that adding FCP to the ASD soil surface by dispersal significantly increases the level of penetration resistance of soil biocrust (PRSB) nine weeks after a single treatment. However, it was not known whether a similar effect could be obtained by administering the FCP in liquid form by means of spraying. It has now been found that spraying a water solution of FCP onto the ASD soil surface significantly increased the level of penetration resistance of soil biocrust (PRSB) three weeks after a single treatment. These results suggest that FCP spraying can be used as a short-term soil stability-enhancing agent for ASD, while administration by dispersal might be more efficient over the long term. Finally, an additional benefit of using FCP as a soil stabilizer, either by dispersal or by spraying, is the reduction in environmental pollution that would otherwise result from the disposal of FCP solid waste. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=active%20sand%20dunes" title="active sand dunes">active sand dunes</a>, <a href="https://publications.waset.org/abstracts/search?q=filter%20cake%20powder" title=" filter cake powder"> filter cake powder</a>, <a href="https://publications.waset.org/abstracts/search?q=biological%20soil%20crusts" title=" biological soil crusts"> biological soil crusts</a>, <a href="https://publications.waset.org/abstracts/search?q=penetration%20resistance%20of%20soil%20biocrust" title=" penetration resistance of soil biocrust"> penetration resistance of soil biocrust</a> </p> <a href="https://publications.waset.org/abstracts/131395/the-effect-of-filter-cake-powder-on-soil-stability-enhancement-in-active-sand-dunes-in-the-long-and-short-term" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/131395.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">164</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Binge Eating among Women Who Suffer from Psychological Abuse in Their Relationship: The Moderating Role of Defense Mechanisms</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Orly%20Yona%20Drori">Orly Yona Drori</a>, <a href="https://publications.waset.org/abstracts/search?q=Shirley%20Ben%20Shlomo"> Shirley Ben Shlomo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The participants will be able to recognize the predictors of binge eating addiction among women who suffer from psychological abuse in their relationships and will recognize the role of woman's defense mechanisms in moderating the association between psychological abuse and binge eating addiction. Methods: A convenience sample of 380 Israeli women in relationships were located via the Internet, and after consenting to participate in the study, they completed a series of structured questionnaires (The Yale Food Addiction Scale; The Defense Style Questionnaire; psychological maltreatment of women by their male partners; level of differentiation of self; sociodemographic questionnaire). Results: The higher the level of differentiation and mature defense mechanisms, the less addictive a woman is. However, the level of addiction among women who experience psychological abuse within their intimate relations is higher than women who do not experience psychological abuse in their relationship. Among women who experienced psychological abuse in their relations, the defense mechanisms moderate the association between psychological abuse within intimate relations and the extent of the addiction to binge eating. Conclusions: The study contributes to the therapy of women with binge eating addictions, as it raises awareness of therapeutic-related content that could strengthen women and help them to cope with situations in their lives without the need to binge. One of the significant variables for therapeutic work is the level of differentiation of the self. In addition, identifying the types of defense mechanisms might help to match treatment to the woman's emotional needs. The current study found also that it is important to identify the environmental systems by which the addict is surrounded, such as whether woman is in an abusive relationship. Finally the study leads to the recognition that binge eating, which is usually treated with an emphasis on nutritional behavior change, is an addiction, and as such, it requires a combination of mental, nutritional and behavioral therapy. In view of this approach, it is recommended that treating a woman who is addicted to binge eating should involve a multi-disciplinary team comprised of physicians, clinical dietitians, and clinical psychotherapists. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=binge%20eating" title="binge eating">binge eating</a>, <a href="https://publications.waset.org/abstracts/search?q=defence%20mechanism" title=" defence mechanism"> defence mechanism</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20addiction" title=" food addiction"> food addiction</a>, <a href="https://publications.waset.org/abstracts/search?q=psychological%20abuse" title=" psychological abuse"> psychological abuse</a> </p> <a href="https://publications.waset.org/abstracts/100452/binge-eating-among-women-who-suffer-from-psychological-abuse-in-their-relationship-the-moderating-role-of-defense-mechanisms" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/100452.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">169</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Dietary Patterns and Hearing Loss in Older People</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20E.%20Gallagher">N. E. Gallagher</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20E.%20Neville"> C. E. Neville</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Lyner"> N. Lyner</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Yarnell"> J. Yarnell</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20C.%20Patterson"> C. C. Patterson</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20E.%20Gallacher"> J. E. Gallacher</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Ben-Shlomo"> Y. Ben-Shlomo</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Fehily"> A. Fehily</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20V.%20Woodside"> J. V. Woodside</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hearing loss is highly prevalent in older people and can reduce quality of life substantially. Emerging research suggests that potentially modifiable risk factors, including risk factors previously related to cardiovascular disease risk, may be associated with a decreased or increased incidence of hearing loss. This has prompted investigation into the possibility that certain nutrients, foods or dietary patterns may also be associated with incidence of hearing loss. The aim of this study was to determine any associations between dietary patterns and hearing loss in men enrolled in the Caerphilly study. The Caerphilly prospective cohort study began in 1979-1983 with recruitment of 2512 men aged 45-59 years. Dietary data was collected using a self-administered, semi-quantitative, 56-item food frequency questionnaire (FFQ) at baseline (1979-1983), and 7-day weighed food intake (WI) in a 30% sub-sample, while pure-tone unaided audiometric threshold was assessed at 0.5, 1, 2 and 4 kHz, between 1984 and 1988. Principal components analysis (PCA) was carried out to determine a posteriori dietary patterns and multivariate linear and logistic regression models were used to examine associations with hearing level (pure tone average (PTA) of frequencies 0.5, 1, 2 and 4 kHz in decibels (dB)) for linear regression and with hearing loss (PTA>25dB) for logistic regression. Three dietary patterns were determined using PCA on the FFQ data- Traditional, Healthy, High sugar/Alcohol avoider. After adjustment for potential confounding factors, both linear and logistic regression analyses showed a significant and inverse association between the Healthy pattern and hearing loss (P<0.001) and linear regression analysis showed a significant association between the High sugar/Alcohol avoider pattern and hearing loss (P=0.04). Three similar dietary patterns were determined using PCA on the WI data- Traditional, Healthy, High sugar/Alcohol avoider. After adjustment for potential confounding factors, logistic regression analyses showed a significant and inverse association between the Healthy pattern and hearing loss (P=0.02) and a significant association between the Traditional pattern and hearing loss (P=0.04). A Healthy dietary pattern was found to be significantly inversely associated with hearing loss in middle-aged men in the Caerphilly study. Furthermore, a High sugar/Alcohol avoider pattern (FFQ) and a Traditional pattern (WI) were associated with poorer hearing levels. Consequently, the role of dietary factors in hearing loss remains to be fully established and warrants further investigation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ageing" title="ageing">ageing</a>, <a href="https://publications.waset.org/abstracts/search?q=diet" title=" diet"> diet</a>, <a href="https://publications.waset.org/abstracts/search?q=dietary%20patterns" title=" dietary patterns"> dietary patterns</a>, <a href="https://publications.waset.org/abstracts/search?q=hearing%20loss" title=" hearing loss"> hearing loss</a> </p> <a href="https://publications.waset.org/abstracts/48034/dietary-patterns-and-hearing-loss-in-older-people" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48034.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">230</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> The Gut Microbiome in Cirrhosis and Hepatocellular Carcinoma: Characterization of Disease-Related Microbial Signature and the Possible Impact of Life Style and Nutrition</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lena%20Lapidot">Lena Lapidot</a>, <a href="https://publications.waset.org/abstracts/search?q=Amir%20Amnon"> Amir Amnon</a>, <a href="https://publications.waset.org/abstracts/search?q=Rita%20Nosenko"> Rita Nosenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Veitsman%20Ella"> Veitsman Ella</a>, <a href="https://publications.waset.org/abstracts/search?q=Cohen-Ezra%20Oranit"> Cohen-Ezra Oranit</a>, <a href="https://publications.waset.org/abstracts/search?q=Davidov%20Yana"> Davidov Yana</a>, <a href="https://publications.waset.org/abstracts/search?q=Segev%20Shlomo"> Segev Shlomo</a>, <a href="https://publications.waset.org/abstracts/search?q=Koren%20Omry"> Koren Omry</a>, <a href="https://publications.waset.org/abstracts/search?q=Safran%20Michal"> Safran Michal</a>, <a href="https://publications.waset.org/abstracts/search?q=Ben-Ari%20Ziv"> Ben-Ari Ziv</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer related mortality worldwide. Liver Cirrhosis is the main predisposing risk factor for the development of HCC. The factor(s) influencing disease progression from Cirrhosis to HCC remain unknown. Gut microbiota has recently emerged as a major player in different liver diseases, however its association with HCC is still a mystery. Moreover, there might be an important association between the gut microbiota, nutrition, life style and the progression of Cirrhosis and HCC. The aim of our study was to characterize the gut microbial signature in association with life style and nutrition of patients with Cirrhosis, HCC-Cirrhosis and healthy controls. Design: Stool samples were collected from 95 individuals (30 patients with HCC, 38 patients with Cirrhosis and 27 age, gender and BMI-matched healthy volunteers). All participants answered lifestyle and Food Frequency Questionnaires. 16S rRNA sequencing of fecal DNA was performed (MiSeq Illumina). Results: There was a significant decrease in alpha diversity in patients with Cirrhosis (qvalue=0.033) and in patients with HCC-Cirrhosis (qvalue=0.032) compared to healthy controls. The microbiota of patients with HCC-cirrhosis compared to patients with Cirrhosis, was characterized by a significant overrepresentation of Clostridium (pvalue=0.024) and CF231 (pvalue=0.010) and lower expression of Alphaproteobacteria (pvalue=0.039) and Verrucomicrobia (pvalue=0.036) in several taxonomic levels: Verrucomicrobiae, Verrucomicrobiales, Verrucomicrobiaceae and the genus Akkermansia (pvalue=0.039). Furthermore, we performed an analysis of predicted metabolic pathways (Kegg level 2) that resulted in a significant decrease in the diversity of metabolic pathways in patients with HCC-Cirrhosis (qvalue=0.015) compared to controls, one of which was amino acid metabolism. Furthermore, investigating the life style and nutrition habits of patients with HCC-Cirrhosis, we found significant correlations between intake of artificial sweeteners and Verrucomicrobia (qvalue=0.12), High sugar intake and Synergistetes (qvalue=0.021) and High BMI and the pathogen Campylobacter (qvalue=0.066). Furthermore, overweight in patients with HCC-Cirrhosis modified bacterial diversity (qvalue=0.023) and composition (qvalue=0.033). Conclusions: To the best of the our knowledge, we present the first report of the gut microbial composition in patients with HCC-Cirrhosis, compared with Cirrhotic patients and healthy controls. We have demonstrated in our study that there are significant differences in the gut microbiome of patients with HCC-cirrhosis compared to Cirrhotic patients and healthy controls. Our findings are even more pronounced because the significantly increased bacteria Clostridium and CF231 in HCC-Cirrhosis weren't influenced by diet and lifestyle, implying this change is due to the development of HCC. Further studies are needed to confirm these findings and assess causality. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Cirrhosis" title="Cirrhosis">Cirrhosis</a>, <a href="https://publications.waset.org/abstracts/search?q=Hepatocellular%20carcinoma" title=" Hepatocellular carcinoma"> Hepatocellular carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=life%20style" title=" life style"> life style</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20disease" title=" liver disease"> liver disease</a>, <a href="https://publications.waset.org/abstracts/search?q=microbiome" title=" microbiome"> microbiome</a>, <a href="https://publications.waset.org/abstracts/search?q=nutrition" title=" nutrition"> nutrition</a> </p> <a href="https://publications.waset.org/abstracts/96178/the-gut-microbiome-in-cirrhosis-and-hepatocellular-carcinoma-characterization-of-disease-related-microbial-signature-and-the-possible-impact-of-life-style-and-nutrition" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96178.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">129</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" 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