SEER-Linked Virtual Tissue Repository (VTR) Program

<!doctype html> <html lang="en"> <head> <meta charset="UTF-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1"> <meta name="viewport" content="width=device-width, initial-scale=1" /> <title>SEER-Linked Virtual Tissue Repository (VTR) Program</title> <script src="/j/jquery-3.6.0.min.js"></script> <link rel="stylesheet" href="/bootstrap/css/bootstrap.min.css" /> <link rel="stylesheet" href="/s/base.css" /> <link rel="stylesheet" href="/s/styles.css" /> <link rel="preconnect" href="https://www.googletagmanager.com"> <link rel="preconnect" href="https://static.cancer.gov"> <link rel="preconnect" href="https://www.platform.twitter.com">   <meta name="twitter:card" content="summary" /> <meta name="twitter:image" content="https://seer.cancer.gov/i/tile-fact.jpg" />  <meta property="og:type" content="article" /> <meta property="og:image" content="https://seer.cancer.gov/i/tile-fact.jpg" /> <meta property="og:site_name" content="SEER" /> <style> a[data-bs-toggle="modal"].honest { border-bottom: 1px dashed #2e2f31; cursor: help; text-decoration: none !important; color: #444444; } a[data-bs-toggle="modal"].honest:after { content: "?"; background-color: #142c68; width: 22px; height: 22px; font-size: 12px; font-weight: bold; position: relative; text-align: center; color: #ffffff; border-radius: 100px; margin-left: 2px; display: inline-block; vertical-align: super; } @media (min-width: 992px){ .modal-lg, .modal-xl { max-width: 80%; } } </style>  <meta name="description" content="Learn about SEER-Linked Virtual Tissue Repository (VTR) Program: an infrastructure for researchers and other requestors to obtain de-identified, but linked, tissue and data on cancer cases ascertained by the SEER Program cancer registries."> <meta property="twitter:title" content="SEER-Linked Virtual Tissue Repository (VTR) Program"> <meta property="twitter:description" content="Learn about SEER SEER-Linked Virtual Tissue Repository (VTR) Program: an infrastructure for researchers and other requestors to obtain de-identified, but linked, tissue and data on cancer cases ascertained by the SEER Program cancer registries."> <meta property="twitter:url" content="https://seer.cancer.gov/vtr/index.html"> <meta property="og:title" content="SEER-Linked Virtual Tissue Repository (VTR) Program"> <meta property="og:description" content="Learn about SEER-Linked Virtual Tissue Repository (VTR) Program: an infrastructure for researchers and other requestors to obtain de-identified, but linked, tissue and data on cancer cases ascertained by the SEER Program cancer registries."> <meta property="og:url" content="https://seer.cancer.gov/vtr/index.html"> </head> <body class="about " onload='IMS_Onload.run();'> <a class="visually-hidden-focusable" href="#skipnav">Skip to Main Content</a>    <header class="push" role="banner">  <section id="usa-banner" aria-label="Official government website"> <div class="container-lg"> <div class="row"> <div class="usa-banner__header-text py-3"> <img class="me-2" src="/i/usa-banner-flag-icon.png" alt="" /> An official website of the United States government </div> </div> </div> </section>  <div class="container-lg"> <div class="row"> <div class="col-md-8"> <a class="seerLogo" href="/" title="Return Home"> <img src="/i/seer.svg" alt="Surveillance, Epidemiology, and End Results Program" width="1022.1" height="85.8" /> </a> </div> <div class="col-md-4 search"> <div class="share"> <a class="facebook-share-button" href="" onclick="javascript:window.open(this.href, '', 'menubar=no,toolbar=no,resizable=yes,scrollbars=yes,height=300,width=600');return false;" target="_blank"> <svg aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="12" height="12" fill="currentColor" viewBox="0 0 16 16"> <path d="M16 8.049c0-4.446-3.582-8.05-8-8.05C3.58 0-.002 3.603-.002 8.05c0 4.017 2.926 7.347 6.75 7.951v-5.625h-2.03V8.05H6.75V6.275c0-2.017 1.195-3.131 3.022-3.131.876 0 1.791.157 1.791.157v1.98h-1.009c-.993 0-1.303.621-1.303 1.258v1.51h2.218l-.354 2.326H9.25V16c3.824-.604 6.75-3.934 6.75-7.951z"/> </svg> Share <span class="visually-hidden"> on Facebook</span> </a> <a href="https://twitter.com/share?ref_src=twsrc%5Etfw" class="twitter-share-button" data-size="small" data-dnt="true" data-show-count="false">Tweet</a> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script> <a class="print text-nowrap" href="javascript:window.print();"> <svg aria-hidden="true" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" fill="#fff" viewBox="0 0 32 32"> <g><path d="M24.67 10.62h-2.86V7.49H10.82v3.12H7.95c-.5 0-.9.4-.9.9v7.66h3.77v1.31L15 24.66h6.81v-5.44h3.77v-7.7c-.01-.5-.41-.9-.91-.9zM11.88 8.56h8.86v2.06h-8.86V8.56zm10.98 9.18h-1.05v-2.1h-1.06v7.96H16.4c-1.58 0-.82-3.74-.82-3.74s-3.65.89-3.69-.78v-3.43h-1.06v2.06H9.77v-3.58h13.09v3.61zm.75-4.91c-.4 0-.72-.32-.72-.72s.32-.72.72-.72c.4 0 .72.32.72.72s-.32.72-.72.72zm-4.12 2.96h-6.1v1.06h6.1v-1.06zm-6.11 3.15h6.1v-1.06h-6.1v1.06z"></path></g> </svg> <span>Print</span> </a> </div> <form action="/search" method="get" name="search" onSubmit="return searchCheck(this.q) && NCIAnalytics.SiteSearch(this);"> <label for="searchsite">Search SEER:</label> <input id="searchsite" type="text" size="15" name="q" placeholder="Search SEER" /> <input type="image" src="/i/search_btn.png" class="greenBtn" alt="Search"/> </form> </div> </div> </div> </header> <div id="topnav">    <nav class="navbar navbar-expand-lg navbar-dark" aria-labelledby="offcanvasLabel"> <div class="container-lg"> <button class="navbar-toggler my-2 py-1" id="mainNavToggler" type="button" data-bs-toggle="offcanvas" data-bs-target="#mainNav" aria-controls="mainNav" aria-expanded="false" aria-label="Toggle navigation"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path d="M0 96C0 78.3 14.3 64 32 64H416c17.7 0 32 14.3 32 32s-14.3 32-32 32H32C14.3 128 0 113.7 0 96zM0 256c0-17.7 14.3-32 32-32H416c17.7 0 32 14.3 32 32s-14.3 32-32 32H32c-17.7 0-32-14.3-32-32zM448 416c0 17.7-14.3 32-32 32H32c-17.7 0-32-14.3-32-32s14.3-32 32-32H416c17.7 0 32 14.3 32 32z"/></svg> <strong class="align-middle">Main Menu</strong> </button> <div class="offcanvas offcanvas-start container-fluid px-0" id="mainNav" aria-controls="offcanvasLabel" aria-labelledby="offcanvasLabel" data-bs-scroll="true"> <div class="offcanvas-header"> <div class="menu-label-wrapper"><div class="navbar-brand d-lg-none seer-logo"></div> <h3 class="offcanvas-title text-white" id="offcanvasLabel">Main Menu</h3></div> <button type="button" class="btn-close text-reset me-1" data-bs-dismiss="offcanvas" aria-label="Close"></button> </div> <div class="offcanvas-body"> <ul class="navbar-nav mb-2 mb-lg-0 w-100"> <li class="nav-item short-text"> <a class="nav-link active" href="/" id="home-nav">Home</a> </li> <li class="nav-item dropdown"> <button class="nav-link dropdown-toggle text-nowrap" href="#" id="cancerStatisticsDropdown" role="button" data-bs-toggle="dropdown" aria-expanded="false"> Cancer Statistics </button> <ul class="dropdown-menu three-column" aria-labelledby="cancerStatisticsDropdown"> <div class="container-lg"> <div class="row dropdown-header-wrapper"> <div class="col-12 ps-lg-0"> <li class="pe-0 ps-lg-0"> <a class="dropdown-item dropdown-header landing-link" href="/statistics/">Cancer Statistics</a> </li> </div> </div> <div class="row"> <div class="col-lg-4"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/statistics/reports.html">Reports on Cancer</a></li> <li><a class="dropdown-item" href="/report_to_nation/">Annual Report to the Nation on the Status of Cancer</a></li> <li><a class="dropdown-item" href="/statfacts/">Cancer Stat Facts</a></li> <li><a class="dropdown-item" href="/statistics/preliminary-estimates/">Preliminary Cancer Incidence Rates and Trends</a></li> <li class="d-lg-none"><a class="dropdown-item" href="/publications/">SEER Publications</a></li> </ul> </div> <div class="col-lg-4"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/statistics/interactive.html">Interactive Tools, Maps, & Graphs</a></li> <li><a class="dropdown-item" href="/statistics-network/">Cancer Statistics Explorer Network</a></li> <li><a class="dropdown-item" href="/canques/">Cancer Query System</a></li> </ul> </div> <div class="col-lg-4"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/statistics/resources.html">Understanding Statistics</a></li> <li><a class="dropdown-item" href="/statistics/videos/">Did You Know? Video Series</a></li> <li><a class="dropdown-item" href="/statistics/types.html">Defining Cancer Statistics</a></li> <li><a class="dropdown-item" href="/cgi-bin/glossary/glossary.pl">Glossary of Statistical Terms</a></li> </ul> </div> </div> </div> </ul> </li> <li class="nav-item dropdown"> <button class="nav-link dropdown-toggle text-nowrap" href="#" id="dataSoftwareDropdown" role="button" data-bs-toggle="dropdown" aria-expanded="false"> SEER Data & Software </button> <ul class="dropdown-menu four-column" aria-labelledby="dataSoftwareDropdown"> <div class="container-lg"> <div class="row dropdown-header-wrapper"> <div class="col-12 ps-lg-0"> <li class="pe-0 ps-lg-0"> <a class="dropdown-item dropdown-header landing-link" href="/data-software/">SEER Data & Software</a> </li> </div> </div> <div class="row"> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/data/">SEER Incidence Database</a></li> <li><a class="dropdown-item" href="/data/product-comparison.html">Comparison of Data Products</a></li> <li><a class="dropdown-item" href="/data/access.html">How to Request the Data</a></li> </ul> </div> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/data-software/documentation/">Documentation for Data</a></li> <li><a class="dropdown-item" href="/data-software/documentation/seerstat/">SEER*Stat Database Details</a></li> <li><a class="dropdown-item" href="/analysis/">Variable and Recode Definitions</a></li> </ul> </div> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/data-software/datasets.html">U.S. Datasets</a></li> <li><a class="dropdown-item" href="/mortality/">U.S. Mortality</a></li> <li><a class="dropdown-item" href="/data-software/uspopulations.html">U.S. Populations</a></li> <li><a class="dropdown-item" href="/stdpopulations/">Standard Populations</a></li> <li><a class="dropdown-item" href="/data-software/linked_databases.html">SEER Linked Databases</a></li> </ul> </div> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/data-software/software.html">Statistical Software</a></li> <li><a class="dropdown-item" href="/seerstat/">SEER*Stat</a></li> <li><a class="dropdown-item" href="/seerprep/">SEER*Prep</a></li> <li><a class="dropdown-item exit pe-5 pe-lg-2" href="https://surveillance.cancer.gov/tools/">Methods & Tools for Population-based Cancer Statistics</a></li> </ul> </div> </div> </div> </ul> </li> <li class="nav-item dropdown"> <button class="nav-link dropdown-toggle text-nowrap" href="#" id="registryOperationsDropdown" role="button" data-bs-toggle="dropdown" aria-expanded="false"> Registry Operations </button> <ul class="dropdown-menu four-column" aria-labelledby="registryOperationsDropdown"> <div class="container-lg"> <div class="row dropdown-header-wrapper"> <div class="col-12 ps-lg-0"> <li class="pe-0 ps-lg-0"> <a class="dropdown-item dropdown-header landing-link" href="/registrars/">Registry Operations</a> </li> </div> </div> <div class="row"> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/registrars/guidelines.html">Reporting Guidelines</a></li> <li><a class="dropdown-item" href="/tools/codingmanuals/">SEER Program Coding Manual</a></li> <li><a class="dropdown-item" href="/tools/heme/">Hematopoietic Project</a></li> <li><a class="dropdown-item" href="/tools/solidtumor/">Solid Tumor Rules</a></li> </ul> </div> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/registrars/tools-software.html">Tools & Software</a></li> <li><a class="dropdown-item" href="/seertools/glossary/">Glossary for Registrars</a></li> <li><a class="dropdown-item" href="/tools/seerrx/">SEER*Rx - Drug Database</a></li> <li><a class="dropdown-item" href="/seerabs/">SEER Abstracting Tool</a></li> <li><a class="dropdown-item" href="/seerdms/">SEER Data Management System (SEER*DMS)</a></li> </ul> </div> <div class="col-lg-3"> <ul class="multi-column-dropdown mb-lg-2"> <li><a class="dropdown-item dropdown-header" href="/registrars/staging.html">Staging</a></li> <li><a class="dropdown-item" href="/tools/staging/rsa.html">Registrar Staging Assistant (SEER*RSA)</a></li> <li><a class="dropdown-item" href="/tools/ssm/">Summary Stage 2018</a></li> <li><a class="dropdown-item" href="/tools/staging/index.html">Staging Resources</a></li> <li><a class="dropdown-item" href="/tools/staging/eod/" id="eod-menu-link">Extent of Disease 2018</a></li> </ul> </div> <div class="col-lg-3"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/registrars/qa.html">Questions & Answers</a></li> <li><a class="dropdown-item" href="/seer-inquiry/">SEER Inquiry System</a></li> <li><a class="dropdown-item" href="/registrars/contact.html">Ask a SEER Registrar</a></li> <li><a class="dropdown-item" href="/registrars/data-collection.html">Data Collection Answers</a></li> </ul> <li class="mb-0 mb-lg-3"><a class="dropdown-item dropdown-header unlisted-children" href="/cancerpathchart/">Cancer PathCHART</a></li> <li class="mb-0 mb-lg-3"><a class="dropdown-item dropdown-header" href="/training/">Training</a></li> </div> </div> </div> </ul> </li> <li class="nav-item"> <a class="nav-link text-nowrap text-nowrap" href="/news/" id="news-nav">News & Events</a> </li> <li class="nav-item dropdown short-text"> <button class="nav-link dropdown-toggle text-nowrap" href="#" id="aboutDropdown" role="button" data-bs-toggle="dropdown" aria-expanded="false"> About SEER </button> <ul class="dropdown-menu three-column" aria-labelledby="aboutDropdown"> <div class="container-lg"> <div class="row dropdown-header-wrapper"> <div class="col-12 ps-lg-0"> <li class="pe-0 ps-lg-0"> <a class="dropdown-item dropdown-header landing-link" href="/about/">About SEER</a> </li> </div> </div> <div class="row"> <div class="col-lg-4"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/about/overview.html">Program Overview</a></li> <li><a class="dropdown-item" href="/about/goals.html">Goals of the SEER Program</a></li> <li><a class="dropdown-item" href="/about/factsheets/">Fact Sheets & Brochures</a></li> <li><a class="dropdown-item" href="/about/organizations.html">Collaborating Organizations</a></li> </ul> </div> <div class="col-lg-4"> <ul class="multi-column-dropdown"> <li><a class="dropdown-item dropdown-header" href="/registries/">SEER Registries</a></li> <li><a class="dropdown-item" href="/registries/cancer_registry/">What is a Cancer Registry?</a></li> <li><a class="dropdown-item" href="/registries/list.html">List of Registries</a></li> <li><a class="dropdown-item" href="/registries/terms.html">Registry Groupings</a></li> <li><a class="dropdown-item" href="/registries/characteristics.html">Population Characteristics</a></li> </ul> </div> <div class="col-lg-4"> <ul class="multi-column-dropdown mb-lg-2"> <li><a class="dropdown-item dropdown-header" href="/about/activities.html">Research Activities</a></li> <li><a class="dropdown-item" href="/biospecimen/">Residual Tissue Repository Program</a></li> <li><a class="dropdown-item" href="/vtr/">SEER-Linked Virtual Tissue Repository Program</a></li> </ul> <li class="mb-0 mb-lg-3"><a class="dropdown-item dropdown-header unlisted-children" href="/qi/">SEER Quality Improvement</a></li> </div> </div> </div> </ul> </li> </ul> </div> </div>  </div> </nav>    </div>     <div class="section"> <div class="highlighted">  <div class="container-lg"> <button class="togLeftNav button" data-bs-toggle="modal" data-bs-target="#leftNav"><span>Section Menu</span></button> <ol class="breadcrumb"><li class="breadcrumb-item"><a href="/">Home</a> </li><li class="breadcrumb-item"><a href="/about/">About SEER</a> </li><li class="breadcrumb-item mobile-crumb"><a href="/about/activities.html">Research Activities</a> </li><li class="breadcrumb-item" aria-current="page">SEER-Linked Virtual Tissue Repository (VTR) Program</li></ol> <h1>SEER-Linked Virtual Tissue Repository (VTR) Program</h1> </div> </div> <div class="container-lg body ps-lg-0 pb-4"><img src="/i/left-body.png" alt="" class="bg-front"> <div class="row">  <div class="col-lg-3"> <div class="leftNav-wrap"> <nav class="subNav leftNav" aria-label="About SEER"> <strong><a href="/about/">About SEER</a></strong> <ul> <li> <a href="/about/overview.html">Program Overview</a> <ul> <li><a href="/about/goals.html">Goals of the SEER Program</a></li> <li><a href="/about/factsheets/">Fact Sheets & Brochures</a></li> <li><a href="/about/organizations.html">Collaborating Organizations</a></li> </ul> </li> <li> <a href="/registries/">SEER Registries</a> <ul> <li><a href="/registries/cancer_registry/">What is a Cancer Registry?</a> <ul> <li><a href="/registries/cancer_registry/cancer_registry.html">Cancer Registry</a></li> <li><a href="/registries/cancer_registry/data_collection.html">Data Collection, Storage, & Management</a></li> <li><a href="/registries/cancer_registry/dissemination.html">Dissemination</a></li> <li><a href="/registries/cancer_registry/analysis.html">Analysis</a></li> <li><a href="/registries/cancer_registry/research_application.html">Research Application</a></li> <li><a href="/registries/cancer_registry/resources.html">Resources</a></li> </ul> </li> <li><a href="/registries/list.html">List of Registries</a></li> <li><a href="/registries/terms.html">Registry Groupings in SEER Data and Statistics</a></li> <li><a href="/registries/characteristics.html">Population Characteristics</a></li> </ul> </li> <li><a href="/about/activities.html">Research Activities</a> <ul> <li><a href="/biospecimen/">Residual Tissue Repository Program</a> <ul> <li><a href="/biospecimen/resources.html">Pancreatic Tissue Microarray</a></li> <li><a href="/biospecimen/application.html">Applying for Specimens</a></li> <li><a href="/biospecimen/registries.html">Participating Registries</a></li> <li><a href="/biospecimen/regulations.html">Research Regulations</a></li> <li><a href="/biospecimen/publications.html">Accomplishments & Publications</a></li> </ul> </li> <li><a class="active" href="/vtr/">SEER-Linked Virtual Tissue Repository (VTR) Program</a> <ul> <li><a href="/vtr/data.html">Data & Biospecimens</a></li> <li><a href="/vtr/request.html">Request Inquiry & Submissions</a></li> <li><a href="/vtr/cost.html">Cost Structure, Fees, & Payments</a></li> <li><a href="/vtr/faq.html">FAQs</a></li> <li><a href="/vtr/study-info-form.html">Study Information Form (F1)</a></li> <li><a href="/vtr/study-request-form.html">Study Request Form (F2)</a></li> <li><a href="/vtr/contact.html">Contact Us</a></li> </ul> </li> </ul> </li> <li> <a href="/qi/">SEER Quality Improvement</a> <ul> <li><a href="/qi/process.html">Quality Improvement Process</a></li> <li><a href="/qi/tools/">Quality Improvement Tools</a></li> <li><a href="/qi/publications.html">Publications</a></li> <li><a href="/qi/education.html">Education & Training</a></li> </ul> </li> </ul> </nav> </div> </div>  <main class="col-lg-9" id="content" role="main"> <a name="skipnav" id="skipnav" tabindex="-1"></a> <div class="callout"> <h2>Why is a population-based biorepository so critical?</h2> <ul> <li>Currently, most tissue-based research is conducted using specimens from people enrolled in clinical trials or investigator-initiated studies conducted at a small number of institutions.</li> <li>The participants in these studies are not necessarily representative of the United States population.</li> </div> <h2>About the SEER-Linked Virtual Tissue Repository (VTR) Program</h2> <p>The Surveillance Research Program (SRP) is addressing this lack of specimens for population-based cancer research by establishing an infrastructure for researchers and other investigators to obtain de-identified, but linked, tissue and data on cancer cases ascertained by the SEER Program cancer registries. In addition to exploring other cancer research questions, investigators can study the following types of cancer cases through the SEER-Linked VTR Program.</p> <ul> <li>Cancers among underrepresented population subgroups</li> <li>Rare cancers</li> <li>Cancer cases with unusual cancer outcomes</li> <li>Early onset cancers</li> <li>Cases with multiple diagnoses of a primary cancer</li> </ul> <p class="d-inline">Participating SEER Program registries function as <div class="modalItem"> <div class="modalItem-trigger"> <a data-bs-toggle="modal" data-bs-target="" class="honest">honest brokers</a> </div> <div class="modalItem-content"> <div class="modalItem-title">What is an Honest broker?</div> <div class="modalItem-body"> <p>A neutral intermediary (person or system) between the researcher and the individual whose tissue and data are being studied.</p> <p>For more information visit the <a href="https://www.hhs.gov/ohrp/sachrp-committee/recommendations/2011-october-13-letter-attachment-d/index.html#:~:text=HONEST%20BROKER%20means%3A,being%20studied%2C%20and%20the%20researcher." target="_blank">HHS website</a>.</p> </div> </div> </div> for providing researchers with de-identified, but linked, archival, formalin-fixed, paraffin-embedded (FFPE) tissue from clinical care and/or clinical data obtained from medical record abstraction for secondary use in cancer research (Figure 1). Researchers may also request de-identified demographic information, outcomes, pathology reports, custom clinical data collection, and/or digital whole slide images (WSIs).</p> <p>Current VTR Program Registries have received approval of their local Institutional Review Board (IRB) and include:</p> <ul> <li><a href="https://www.kcr.uky.edu/">Kentucky Cancer Registry</a><a class="extlink" href="https://www.cancer.gov/policies/linking"><img src="/images/exit.png" alt="External Web Site Policy" title="External Web Site Policy"></a></li> <li><a href="https://sph.lsuhsc.edu/louisiana-tumor-registry/">Louisiana Tumor Registry</a><a class="extlink" href="https://www.cancer.gov/policies/linking"><img src="/images/exit.png" alt="External Web Site Policy" title="External Web Site Policy"></a></li> </ul> <p>The SEER-Linked VTR Program will prioritize academic projects.</p> <div class="modalItem"> <div class="modalItem-trigger"> <figure> <figcaption>Figure 1: How does the SEER-Linked VTR Program work?</figcaption> <a data-bs-toggle="modal" data-bs-target=""> <img src="/i/vtr/process.png" alt="request process" /> <p>View larger image</p> </a> </figure> </div> <div class="modalItem-content"> <div class="modalItem-title">Figure 1: How does the SEER-Linked VTR Program work? </div> <div class="modalItem-body"> <img src="/i/vtr/process.png" alt="request process" /> <p>Following are the general steps in the SEER-Linked VTR Program operations. For details about request submission visit <a href="request.html">VTR Request Inquiry & Submissions</a>.</p> <ol> <li>Investigator submits request to SEER-Linked VTR Program.</li> <li>Study is reviewed by NCI and SEER VTR Registries.</li> <li>SEER VTR Registry meets with investigator about study design, and investigator submits the final request.</li> <li>SEER VTR Registries act as honest brokers to request (a) clinical records and/or (b) FFPE tissue. </li> <li>Treating facilities and pathology laboratories send (a) clinical records and/or (b) FFPE tissue to the SEER VTR Registry for processing and de-identification. <li>SEER VTR Registry sends de-identified, linked data and/or tissue the investigator.</li> </ol> </div> </div> </div> <h2>Rationale for SEER Registries as Honest Brokers</h2> <p>The SEER cancer registry system serves as an ideal infrastructure for the development of a VTR for the following reasons. These population-based registries </p> <ul> <li>serve as a renewable resource with approximately 994,000 cancer cases ascertained per year</li> <li>conduct active longitudinal follow-up</li> <li>maintain established relationships with hospitals and pathology laboratories</li> <li>have extensive experience in data collection</li> <li>maintain clinical annotation</li> </ul> </main> </div> <img src="/i/right-body.png" alt="" class="bg-back"></div> <div class="wrapper"> <meta http-equiv="last_modified" content="Tue, 19 Nov 2024 13:20:15 -0500" /> </div> </div>  <footer class="footer" role="contentinfo"> <a class="returntop" href="#content" style="display: inline;"><span>Return to Top</span></a> <div class="container-lg"> <div class="row justify-content-around"> <div class="col-lg-9"> <p class="seer-logo">SEER is supported by the <a href="https://surveillance.cancer.gov/">Surveillance Research Program (SRP)</a> in NCI's <a href="https://cancercontrol.cancer.gov/">Division of Cancer Control and Population Sciences (DCCPS)</a>. SRP provides national leadership in the science of cancer surveillance as well as analytical tools and methodological expertise in collecting, analyzing, interpreting, and disseminating reliable population-based statistics.</p> </div> </div> </div> <div class="footer-links"> <div class="container-lg"> <div class="row links-col"> <div class="col-md-3"> <h2>Follow SEER</h2> <ul class="social"> <li><a href="https://surveillance.cancer.gov/blog"><img loading="lazy" src="/i/blog-icon.png" alt="SRP Blog" width="40" height="32"></a></li> <li><a href="https://www.linkedin.com/showcase/nci-cancer-control-and-population-sciences/"><img loading="lazy" src="/i/linkedin-icon.png" alt="DCCPS LinkedIn" width="32" height="32"></a></li> </ul> </div> <div class="col-md-3"> <h2>Contact Information</h2> <ul> <li><a href="/about/contact.html">Contact SEER</a></li> <li><a href="https://livehelp.cancer.gov/">NCI LiveHelp Online Chat</a></li> </ul> </div> <div class="col-md-3"> <h2>More Information</h2> <ul> <li><a href="https://surveillance.cancer.gov/jobs/">Careers</a></li> <li><a href="/sitemap.html">Sitemap</a></li> <li><a href="/about/using-website.html">Using This Website</a></li> </ul> </div> <div class="col-md-3"> <h2>Policies</h2> <ul> <li><a href="https://www.cancer.gov/policies/accessibility">Accessibility</a></li> <li><a href="https://www.cancer.gov/policies/disclaimer">Disclaimer</a></li> <li><a href="https://www.cancer.gov/policies/foia">FOIA</a></li> <li><a href="https://www.hhs.gov/vulnerability-disclosure-policy">HHS Vulnerability Disclosure</a></li> <li><a href="https://www.cancer.gov/policies/privacy-security">Privacy & Security</a></li> <li><a href="https://www.cancer.gov/policies/copyright-reuse">Reuse of Graphics and Text</a></li> <li><a href="https://www.cancer.gov/policies/linking">Website Linking</a></li> </ul> </div> </div> <ul class="linkList ps-0 p-md-2"> <li><a href="https://www.hhs.gov/">U.S. Department of Health and Human Services</a></li> <li><a href="https://www.nih.gov/">National Institutes of Health</a></li> <li><a href="https://www.cancer.gov/">National Cancer Institute</a></li> <li class="last"><a href="https://www.usa.gov/">USA.gov</a></li> </ul> <p class="text-center">NIH... Turning Discovery Into Health<sup>®</sup></p> </div> </div> </footer> <script type="text/javascript" src="/j/general.js"></script> <script src="/bootstrap/js/bootstrap.min.js"></script>  <script src="/j/jquery-ui.min.js" type="text/javascript"></script>  <script async src="https://www.googletagmanager.com/gtag/js?id=UA-125238734-1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'UA-125238734-1'); </script>  <script src="//static.cancer.gov/webanalytics/WA_DCCPS_PageLoad.js"></script>  <script> var fb_page = window.location.href; //current page url var page_title = $("title").text(); //current page title fb_page = "https://www.facebook.com/sharer/sharer.php?u=" + fb_page + "&t=" + page_title; //insert url and title into the FB sharer $(".facebook-share-button").attr('href', fb_page); //add sharer url to link </script>  </body> </html>

CINXE.COM

SEER-Linked Virtual Tissue Repository (VTR) Program