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block block-views block-views-blockgroup-header-block-1" id="block-views-block-group-header-block-1"> <div><div class="view view-group-header view-id-group_header view-display-id-block_1 js-view-dom-id-b3b0cb67c0e78e34f9add5f0654377c1d11967a0db46fb5189274d43be74a6c0"> <div class="view-content"> <div class="views-row"><div class="views-field views-field-field-media-image-3-1"><div class="field-content"><div class="node-header"> <div class="node-header-image" data-node-header-image="/sites/default/files/hero-image/Diagnostic-services-group-header-image.jpg"> <div class="node-header-tab"></div> </div> <div class="node-header-content"> <div class="node-header-wrap"> <h1 class="page-title">CancerTYPE ID®</h1> <span class="blue-bar bar-large"></span> <div class="page-subtitle"></div> </div> </div> </div></div></div></div> </div> </div> </div> </div> <div class="views-element-container block block-views block-views-blockdefault-header-block-1" id="block-views-block-default-header-block-1"> <div><div class="view view-default-header view-id-default_header view-display-id-block_1 js-view-dom-id-ca4f4f74573dad37d9a751f297f576cce83d07e38f46eb63d1bae168e244e235"> </div> </div> </div> </div> </div> </div> </div> <div id="layout-above-content"> <div class="wrap-above-content"> <div class="above-content-content"> <div class="region region-above-content"> <div id="block-neogenomics-breadcrumbs" class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/diagnostic-services">Diagnostic Services</a> </li> <li> <a href="/diagnostic-services/specialty-testing">Specialty Testing</a> </li> <li> CancerTYPE ID®</li> </ol> </nav> </div> </div> </div> </div> </div> <main role="main" class="layout-main"> <div class="wrap-main"> <div class="main-content"> <section class="no-sidebar content-wrap"> <div class="layout-content"> <a id="main-content" tabindex="-1"></a> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <div id="block-neogenomics-content" class="block block-system block-system-main-block"> <article data-history-node-id="1070" class="node node--type-promo node--view-mode-full"> <div class="node__content"> <div class="field field--name-field-section field--type-entity-reference-revisions field--label-hidden field__items"> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-half padding-top-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p class="large">Resolve ambiguous diagnoses, reveal therapeutic targets, and identify clinical trial options with one sample submission.</p> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>NeoGenomics and Biotheranostics, Inc., a Hologic Company, are pleased to provide a combined test offering for metastatic cancer patients with an unknown or unclear diagnosis. CancerTYPE ID<sup>®</sup> with reflex to NeoTYPE<sup>®</sup> Cancer Profile enables tumor type classification and identification of actionable biomarkers in a seamless, single-order process that is available from either company.</p> </div> </div> </div> </div> </div> </div> <div id="" class="paragraph paragraph--type--text-image-equal-height-columns paragraph--view-mode--default"> <div class="equal-height-image-section img-right"> <div class="equal-height-image-content"> <div id="paragraph-id-388" class="media-wrap lazyload-bg" style=";background-image: url('/sites/default/files/styles/lazy_load/public/2021-07/iStock-1266478952.jpg?itok=rTn0jZrK');" data-lazyload="/sites/default/files/2021-07/iStock-1266478952.jpg"></div> <div class="content-wrap" style=""> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h3>Testing helps establish a final diagnosis and follow-up care options in the following situations:</h3> <ul> <li>Poorly differentiated tumors</li> <li>New primary vs. recurrence</li> <li>Unusual presentation</li> </ul> <p>CancerTYPE ID<sup>®</sup> is performed and billed separately by NeoGenomics’ contracted reference laboratory, Biotheranostics, Inc., an independent CLIA-licensed and CAP-accredited reference laboratory. CancerTYPE ID<sup>®</sup> may be ordered as a stand-alone test directly from Biotheranostics, Inc. a Hologic Company. Please see <a href="http://www.cancertypeid.com" target="_blank">www.cancertypeid.com</a>.</p> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-half padding-top-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h3>CancerTYPE ID<sup>®</sup> Performance</h3> <p>CancerTYPE ID<sup>®</sup> is a proprietary molecular assay using RT-PCR to measure expression of 92 genes. To classify the tumor, the gene expression profile is matched to a database of more than 2000 known tumor types and subtypes. Using this technology, CancerTYPE ID<sup>®</sup> can identify 50 different tumor types and subtypes, covering >95% of all solid tumors based on incidence.<sup>1</sup> The test reports a main cancer type with the highest probability, as well as a list of tumor types that may be ruled out with 95% confidence.</p> <p>Extensively validated, CancerTYPE ID<sup>®</sup> has demonstrated 87% accuracy in a multi-institutional validation study led by three Centers of Excellence: UCLA, Mayo Clinic, and MGH.<sup>2</sup> A comparison vs. standard of care IHC also showed that when more than 7-9 stains were required for analysis, the accuracy of IHC fell below 50%, while CancerTYPE ID<sup>®</sup> maintained significantly higher performance, and therefore may provide a tissue-sparing approach to establish the tumor type in these challenging cases.<sup>3</sup> In a prospective clinical trial led by the Sarah Cannon Research Institute, CancerTYPE ID<sup>®</sup> identified a primary tumor type in 98% of cases and therapy based on the CancerTYPE ID<sup>®</sup> result improved overall survival by 37%.<sup>4</sup></p> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h3>Clinical Significance</h3> <p>Determining a single tumor type diagnosis is essential for an oncologist’s ability to effectively treat his or her patient. Although recent studies have investigated whether molecular alterations alone are sufficient to direct treatment, results have had limited actionability due to inconsistent efficacy of the treatments across multiple tumor types.<sup>5</sup> Thus, a definitive diagnosis of the tumor type remains a critical first step for appropriate treatment.</p> <p>While IHC is the standard of care method used to establish an initial pathologic diagnosis, metastatic disease often poses diagnostic challenges, resulting in over 100,000 cases per year that still have some degree of diagnostic ambiguity.<sup>6-8</sup> For these difficult-to-diagnose metastatic cases, CancerTYPE ID<sup>®</sup> provides important tumor type information to resolve diagnostic dilemmas. It can help narrow a differential diagnosis so that clients may confidently report a single final diagnosis<sup>9</sup> and efficiently identify targetable mutations in genes pre-selected for their known impact in that tumor type.</p> </div> </div> </div> </div> </div> </div> <div id="" class="paragraph paragraph--type--wysiwyg-full-width paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h3>Pairing of Classifications with Tumor Profiles</h3> <p>When CancerTYPE ID<sup>®</sup> and NeoTYPE<sup>®</sup> Cancer Profiles are ordered together, the NeoTYPE<sup>®</sup> profile performed will be based on the CancerTYPE ID<sup>®</sup> result as shown in the table below. If <a href="/test-menu/neo-comprehensive-solid-tumor">Neo Comprehensive – Solid Tumor</a> is the preferred and ordered test, Neo Comprehensive – Solid Tumor will be performed instead of a NeoTYPE<sup>®</sup> profile (for non-New York).</p> <table border="1" cellpadding="0" cellspacing="0"> <thead> <tr> <th class="text-align-left" colspan="2" scope="col"><strong>CancerTYPE ID<sup>®</sup> Result</strong></th> <th class="text-align-left" colspan="2" scope="col"><strong>NeoTYPE<sup>®</sup> Profile Reflex</strong></th> </tr> </thead> <tbody> <tr> <td colspan="2">Bladder, urothelial cancer</td> <td colspan="2"> <p><a href="/node/1481" data-entity-type="node" data-entity-uuid="45f8abe0-1839-412b-a132-0ae78081da89" data-entity-substitution="canonical">Neo Comprehensive™ - Solid Tumor</a></p> <hr> <p><span class="disclaimer">For New York</span><br><a href="/test-menu/neotyper-other-solid-tumor-profile">NeoTYPE<sup>®</sup> Other Solid Tumor Profile</a> plus <a href="/test-menu/targeted-solid-tumor-ngs-fusion-panel">Targeted Fusion Panel</a></p> </td> </tr> <tr> <td colspan="2">Brain, meningioma</td> <td colspan="2"> <p><a href="/node/1545" data-entity-type="node" data-entity-uuid="8514235c-63a8-4a7d-a845-a31f6cc31586" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> DNA & RNA - Brain</a> </p> <hr> <p><span class="disclaimer">For New York</span><br><a href="/node/383" data-entity-type="node" data-entity-uuid="87de9656-b269-45b0-894b-f57c9c17cf12" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Discovery Profile for Solid Tumors</a> plus <a href="/node/33" data-entity-type="node" data-entity-uuid="193c7abe-7ed1-4b85-b7d4-4381a61925d7" data-entity-substitution="canonical">1p/19q Deletions FISH</a></p> </td> </tr> <tr> <td colspan="2">Brain, non-meningioma</td> <td colspan="2"> <p><a href="/node/1545" data-entity-type="node" data-entity-uuid="8514235c-63a8-4a7d-a845-a31f6cc31586" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> DNA & RNA - Brain </a></p> <hr> <p><span class="disclaimer">For New York</span><br><a href="/node/383" data-entity-type="node" data-entity-uuid="87de9656-b269-45b0-894b-f57c9c17cf12" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Discovery Profile for Solid Tumors (molecular only)</a> plus <a href="/node/609" data-entity-type="node" data-entity-uuid="414398c1-353d-4ea4-8062-9a6b4c0014ca" data-entity-substitution="canonical">Brain NGS Fusion Panel</a> plus <a href="/node/440" data-entity-type="node" data-entity-uuid="3b36ca58-3afa-4ee7-b749-12048b95d0a8" data-entity-substitution="canonical">MGMT Promoter Methylation</a> plus <a href="/node/1152" data-entity-type="node" data-entity-uuid="92668a78-9374-4f85-bcb7-7748856e4dd8" data-entity-substitution="canonical">PD-L1 LDT</a></p> </td> </tr> <tr> <td colspan="2">Breast adenocarcinoma</td> <td colspan="2"><a href="/node/382" data-entity-type="node" data-entity-uuid="1afa0192-89f7-4972-a5f2-568d32aa5bdb" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Breast Tumor Profile</a></td> </tr> <tr> <td colspan="2">Cervix, adenocarcinoma or squamous cell carcinoma</td> <td colspan="2"><a href="/node/417" data-entity-type="node" data-entity-uuid="67532478-de3f-476a-a094-637bf71414be" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Cervical Tumor Profile</a></td> </tr> <tr> <td colspan="2">Cholangiocarcinoma</td> <td colspan="2"><a href="/node/618" data-entity-type="node" data-entity-uuid="577e5d60-62ed-4892-aaef-6c6991ef947b" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Cholangiocarcinoma</a> plus <a href="/node/611" data-entity-type="node" data-entity-uuid="2f309360-d4b2-4894-a427-56e8640f855c" data-entity-substitution="canonical">Cholangio/Pancreatic Carcinoma NGS Fusion Panel</a></td> </tr> <tr> <td colspan="2">Endometrial adenocarcinoma</td> <td colspan="2"><a href="/node/434" data-entity-type="node" data-entity-uuid="d7ab4dd9-ae48-476a-a74b-21fe5ddfde8f" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Endometrial Tumor Profile</a></td> </tr> <tr> <td colspan="2">Gastroesophageal adenocarcinoma</td> <td colspan="2"><a href="/node/443" data-entity-type="node" data-entity-uuid="d0ace7d0-ec4c-48a5-afbe-815818cf8fdd" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Gastric Tumor Profile</a></td> </tr> <tr> <td colspan="2">Gastrointestinal stromal tumor (GIST)</td> <td colspan="2"><a href="/node/554" data-entity-type="node" data-entity-uuid="f5065bc0-c00c-429e-a6cc-681dbc65c486" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> GIST and Soft Tissue Tumor Profile</a></td> </tr> <tr> <td colspan="2">Head & neck, skin/squamous cell carcinoma</td> <td colspan="2"><a href="/node/324" data-entity-type="node" data-entity-uuid="19858a86-ce1a-4f67-b030-f06205013dd7" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Head & Neck Profile</a> </td> </tr> <tr> <td colspan="2">Intestine, colorectal</td> <td colspan="2"><a href="/node/429" data-entity-type="node" data-entity-uuid="f7571c5d-300c-402c-b91a-4ced046ed295" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Colorectal Tumor Profile</a></td> </tr> <tr> <td colspan="2">Liver, hepatocellular carcinoma</td> <td colspan="2"><a href="/node/389" data-entity-type="node" data-entity-uuid="cf0bd45e-c01a-4f42-a1ce-ce6629ea2d86" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Liver/Biliary Tumor Profile</a></td> </tr> <tr> <td colspan="2">Lung, adenocarcinoma or squamous cell carcinoma</td> <td colspan="2"> <p><a href="/node/1438" data-entity-type="node" data-entity-uuid="81070f7e-c89d-4808-b733-f14e018cc01c" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> DNA & RNA - Lung</a> </p> <hr> <p><span class="disclaimer">For New York</span><br><a href="/node/383" data-entity-type="node" data-entity-uuid="87de9656-b269-45b0-894b-f57c9c17cf12" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Discovery Profile for Solid Tumors</a></p> </td> </tr> <tr> <td colspan="2">Lymphoma</td> <td colspan="2"><a href="/node/1387" data-entity-type="node" data-entity-uuid="ae024432-afb6-4c40-8046-3ea15974c1a7" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Lymphoid Disorders Profile</a></td> </tr> <tr> <td colspan="2">Melanoma</td> <td colspan="2"><a href="/node/393" data-entity-type="node" data-entity-uuid="d5ad3e54-5425-49e8-8af1-f88cc52b817a" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Melanoma Tumor Profile</a></td> </tr> <tr> <td colspan="2">Ovary</td> <td colspan="2"><a href="/node/485" data-entity-type="node" data-entity-uuid="ac5d2060-a592-42c3-ad1b-0db3c21a0675" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Ovarian Tumor Profile</a></td> </tr> <tr> <td colspan="2">Pancreaticobiliary, gallbladder adenocarcinoma, pancreatic adenocarcinoma</td> <td colspan="2"><a href="/node/493" data-entity-type="node" data-entity-uuid="020eadd0-966a-4cfe-810f-5e70b42f365c" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Pancreas Tumor Profile</a></td> </tr> <tr> <td colspan="2">Prostate, adenocarcinoma</td> <td colspan="2"><a href="/node/399" data-entity-type="node" data-entity-uuid="f1be71a6-7df0-473c-bcbf-2cb6027697d1" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Precision Profile</a> plus <a href="/node/613" data-entity-type="node" data-entity-uuid="4c7fbbfc-22de-42d8-bfb9-2c1391ed5b65" data-entity-substitution="canonical">Prostate NGS Fusion Panel</a></td> </tr> <tr> <td colspan="2">Salivary gland carcinoma</td> <td colspan="2"><a href="/node/396" data-entity-type="node" data-entity-uuid="7d77b015-1f1d-4584-a2c7-98df6bf97f86" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Other Solid Tumor Profile</a> plus <a href="/node/614" data-entity-type="node" data-entity-uuid="685abf74-852f-4b19-a093-9db6ca4ca29c" data-entity-substitution="canonical">Salivary Gland NGS Fusion Panel</a></td> </tr> <tr> <td colspan="2">Sarcoma</td> <td colspan="2"><a href="/node/383" data-entity-type="node" data-entity-uuid="87de9656-b269-45b0-894b-f57c9c17cf12" data-entity-substitution="canonical">NeoTYPE® Discovery Profile for Solid Tumors</a> (molecular only) plus <a href="/node/460" data-entity-type="node" data-entity-uuid="7cdf6d2d-d24d-46c6-a4ad-321eb4cccdd8" data-entity-substitution="canonical">Sarcoma Comprehensive NGS Fusion Panel</a><br>For liposarcoma, add <a href="/node/63" data-entity-type="node" data-entity-uuid="ec2f1d7e-d3d5-41be-913b-7483b7f0dea6" data-entity-substitution="canonical">MDM2 FISH</a></td> </tr> <tr> <td colspan="2">Thyroid</td> <td colspan="2"><a href="/node/520" data-entity-type="node" data-entity-uuid="191c24aa-98a4-44dd-8c0a-52ab2fa7edb2" data-entity-substitution="canonical">NeoTYPE<sup>®</sup> Thyroid Profile</a> plus <a href="/test-menu?search=thyroid+ngs+fusion+panel&methodology=All&diseases=All" data-entity-type="node" data-entity-uuid="5ce16ee4-3e20-44c3-8236-2f11b9feae90" data-entity-substitution="canonical">Thyroid NGS Fusion Panel</a></td> </tr> <tr> <td colspan="2">Adrenal<br>Germ Cell<br>Intestine, small intestine adenocarcinoma<br>Kidney<br>Mesothelioma<br>Neuroendocrine<br>Sex cord stromal tumor<br>Skin, basal cell carcinoma<br>Thymus<br>Urinary bladder</td> <td colspan="2"> <p><a href="/node/1481" data-entity-type="node" data-entity-uuid="45f8abe0-1839-412b-a132-0ae78081da89" data-entity-substitution="canonical">Neo Comprehensive™ - Solid Tumor</a></p> <hr> <p><span class="disclaimer">For New York</span><br><a href="/test-menu/neotyper-other-solid-tumor-profile">NeoTYPE<sup>®</sup> Other Solid Tumor Profile</a></p> </td> </tr> <tr> <td colspan="2">Indeterminate</td> <td colspan="2"> <p><a href="/node/1481" data-entity-type="node" data-entity-uuid="45f8abe0-1839-412b-a132-0ae78081da89" data-entity-substitution="canonical">Neo Comprehensive - Solid Tumor</a></p> <hr> <p><span class="disclaimer">For New York</span><br><a href="/test-menu/neotyper-discovery-profile-solid-tumors">NeoTYPE<sup>®</sup> Discovery Profile for Solid Tumors</a></p> </td> </tr> </tbody> </table> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-full padding-top-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>References:</p> <ol> <li>Erlander M, et al. <em>J Mol Diagn</em>. 2011;13(5):493-503.</li> <li>Kerr SE, et al. <em>Clin Cancer Res</em>. 2012;18(4):3952-60.</li> <li>Weiss LM, et al.<em> J Mol Diagn</em>. 2013; 15(2):263-269.</li> <li>Hainsworth JD, et al.<em> J Clin Oncol</em>. 2013;31:217-23.</li> <li>Le Tourneau, et al. <em>Lancet Oncol</em>. 2015;16(13):1324-34.</li> <li>Fong TH, et al.<em> J Clin Oncol</em>. 2008;26 (Suppl):22159.</li> <li>Anderson GG, Weiss LM. <em>Appl Immunohistochem Mol Morphol</em>. 2010;18(1)3-8.</li> <li>Shahda S. Metastatic patients with unclear diagnosis. CME presentation at ASCO Puerto Rico (October 2014).</li> <li>Thomas SP, et al.<em> J Clin Oncol.</em> 2015;33(Suppl 3; abst 249).</li> </ol> </div> </div> </div> </div> </div> </div> <div id="" class="paragraph paragraph--type--cards paragraph--view-mode--default"> <div class="cards-section"> <div class="cards-content"> <div class="content-wrap"> <div class="field field--name-field-cards field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="field field--name-field-title field--type-string field--label-hidden field__item">Client Services</div> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p class="text-align-center">NeoGenomics prides itself on our unparalleled customer support team. If you have questions regarding test information, specimen requirements, turnaround times, test add-on, and patient results, please feel free to reach out to a Client Services Advocate at <a href="mailto:client.services@neogenomics.com">client.services@neogenomics.com </a></p> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="field field--name-field-title field--type-string field--label-hidden field__item">CancerTYPE ID® Testing</div> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p class="text-align-center">Find printable ordering information as well as specimen requirements here.</p> <p class="text-align-center"><a class="btn" href="https://neogenomics.com/test-menu/cancertype-idr-reflex-neotyper-cancer-profile">ORDERING INFORMATION</a></p> </div> </div> </div> </div> </div> <div id="paragraph-id-397" class="media-wrap 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