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Activitandeacute; des enzymes antioxydantes et expression de | 105061

<!doctype html> <html lang="fr"> <head> <title>Activitandeacute; des enzymes antioxydantes et expression de | 105061</title> <meta name="keywords" content="Lais Morandini Carvalho, Luana Marotta Reis de Vasconcellos, Elis Andrade Lima Zutin, Elisa Mattias Sartori, Daniela Baccelli Silveira Mendonca, Gustavo Mendonca, Yasmin Rodarte Carvalho , "/> <meta name="description" content="Des &eacute;tudes ont &eacute;t&eacute; orient&eacute;es vers la production de nouveaux alliages de titane, visant &agrave; remplacer l&#39;alliage TiAlV d..105061"/> <meta name="citation_publisher" content="Longdom Publishing SL" /> <meta name="citation_journal_title" content="Annales et Essences de la Dentisterie"> <meta name="citation_title" content="Activitandeacute; des enzymes antioxydantes et expression de RUNX2 sur des andeacute;chafaudages en alliage de titane poreux "> <meta name="citation_author" content="Lais Mor" /> <meta name="citation_author" content="ini Carvalho" /> <meta name="citation_author" content="Luana Marotta Reis de Vasconcellos" /> <meta name="citation_author" content="Elis Andrade Lima Zutin" /> <meta name="citation_author" content="Elisa Mattias Sartori" /> <meta name="citation_author" content="Daniela Baccelli Silveira Mendonca" /> <meta name="citation_author" content="Gustavo Mendonca" /> <meta name="citation_author" content="Yasmin Rodarte Carvalho" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="16"> <meta name="citation_issue" content="1"> <meta name="citation_abstract" content="Des &eacute;tudes ont &eacute;t&eacute; orient&eacute;es vers la production de nouveaux alliages de titane, visant &agrave; remplacer l&#39;alliage TiAlV dans le futur. Par cons&eacute;quent, de nombreux m&eacute;canismes li&eacute;s &agrave; la biocompatibilit&eacute; et aux caract&eacute;ristiques chimiques ont &eacute;t&eacute; &eacute;tudi&eacute;s dans le domaine de l&#39;implantologie, mais jusqu&#39;&agrave; pr&eacute;sent, les d&eacute;fenses enzymatiques contre le stress oxydatif ont &eacute;t&eacute; sous-explor&eacute;es. L&#39;objectif de cette &eacute;tude &eacute;tait d&#39;&eacute;valuer l&#39;activit&eacute; des enzymes antioxydantes Superoxyde Dismutase (SOD) et Catalase (CAT) dans des &eacute;chafaudages poreux de Ti-6 Aluminium-4 Vanadium, Ti-35 Niobium et Ti-35 Niobium-7 Zirconium-5 Tantale. Des &eacute;chafaudages en alliage de titane poreux ont &eacute;t&eacute; pr&eacute;par&eacute;s par m&eacute;tallurgie des poudres. Des cellules souches m&eacute;senchymateuses de f&eacute;mur de souris ont &eacute;t&eacute; utilis&eacute;es. Apr&egrave;s 24 heures, les cellules plaqu&eacute;es sous les &eacute;chafaudages ont &eacute;t&eacute; analys&eacute;es par microscopie &eacute;lectronique &agrave; balayage (MEB). Fran&ccedil;ais L&#39;activit&eacute; des enzymes antioxydantes a &eacute;t&eacute; mesur&eacute;e apr&egrave;s 72 heures de placage cellulaire et apr&egrave;s 3, 7 et 14 jours, les cellules ont &eacute;t&eacute; collect&eacute;es pour &eacute;valuer l&#39;expression de RUNX2 par PCR en temps r&eacute;el. Les images SEM ont montr&eacute; la pr&eacute;sence de pores interconnect&eacute;s et la croissance, l&#39;adh&eacute;sion et la propagation cellulaire dans les 3 &eacute;chafaudages. Nos r&eacute;sultats pour SOD et CAT se sont av&eacute;r&eacute;s meilleurs pour les &eacute;chafaudages TiNbZrTa et TiAlV. L&#39;&eacute;chafaudage TiNb pr&eacute;sentait moins d&#39;activit&eacute; pour les deux enzymes. Malgr&eacute; les diff&eacute;rences entre les &eacute;chafaudages, il n&#39;y avait aucune diff&eacute;rence statistique (p&gt; 0,05). RUNX2 pr&eacute;sentait une expression &eacute;lev&eacute;e pour TiNbZrTa et TiAlV au jour 7 et pr&eacute;sentait des diff&eacute;rences statistiques uniquement pour TiNbZrTa par rapport au groupe t&eacute;moin (TiAlV jour 3). Au jour 14, tous les &eacute;chafaudages pr&eacute;sentaient une expression sup&eacute;rieure &agrave; la ligne de base et pr&eacute;sentaient des diff&eacute;rences statistiques par rapport au groupe t&eacute;moin. Il a &eacute;t&eacute; possible de conclure qu&#39;en ce qui concerne les enzymes antioxydantes, nous ne sommes pas en mesure de confirmer des diff&eacute;rences qui justifieraient le remplacement du TiAlV, mais l&#39;expression g&eacute;n&eacute;tique a montr&eacute; une meilleure capacit&eacute; de diff&eacute;renciation des cellules souches m&eacute;senchymateuses dans TiNbZrTa, ce qui en fait un bon choix pour les applications biom&eacute;dicales. 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</aside> <div class="col-12 col-sm-9"> <h2 class="heading-1">Abstrait</h2> <h3 class="">Activit&eacute; des enzymes antioxydantes et expression de RUNX2 sur des &eacute;chafaudages en alliage de titane poreux </h3> <p> <i class="fas fa-user"></i> Lais Morandini Carvalho, Luana Marotta Reis de Vasconcellos, Elis Andrade Lima Zutin, Elisa Mattias Sartori, Daniela Baccelli Silveira Mendonca, Gustavo Mendonca, Yasmin Rodarte Carvalho </p> <p>Des &eacute;tudes ont &eacute;t&eacute; orient&eacute;es vers la production de nouveaux alliages de titane, visant &agrave; remplacer l&#39;alliage TiAlV dans le futur. Par cons&eacute;quent, de nombreux m&eacute;canismes li&eacute;s &agrave; la biocompatibilit&eacute; et aux caract&eacute;ristiques chimiques ont &eacute;t&eacute; &eacute;tudi&eacute;s dans le domaine de l&#39;implantologie, mais jusqu&#39;&agrave; pr&eacute;sent, les d&eacute;fenses enzymatiques contre le stress oxydatif ont &eacute;t&eacute; sous-explor&eacute;es. L&#39;objectif de cette &eacute;tude &eacute;tait d&#39;&eacute;valuer l&#39;activit&eacute; des enzymes antioxydantes Superoxyde Dismutase (SOD) et Catalase (CAT) dans des &eacute;chafaudages poreux de Ti-6 Aluminium-4 Vanadium, Ti-35 Niobium et Ti-35 Niobium-7 Zirconium-5 Tantale. Des &eacute;chafaudages en alliage de titane poreux ont &eacute;t&eacute; pr&eacute;par&eacute;s par m&eacute;tallurgie des poudres. Des cellules souches m&eacute;senchymateuses de f&eacute;mur de souris ont &eacute;t&eacute; utilis&eacute;es. Apr&egrave;s 24 heures, les cellules plaqu&eacute;es sous les &eacute;chafaudages ont &eacute;t&eacute; analys&eacute;es par microscopie &eacute;lectronique &agrave; balayage (MEB). Fran&ccedil;ais L&#39;activit&eacute; des enzymes antioxydantes a &eacute;t&eacute; mesur&eacute;e apr&egrave;s 72 heures de placage cellulaire et apr&egrave;s 3, 7 et 14 jours, les cellules ont &eacute;t&eacute; collect&eacute;es pour &eacute;valuer l&#39;expression de RUNX2 par PCR en temps r&eacute;el. Les images SEM ont montr&eacute; la pr&eacute;sence de pores interconnect&eacute;s et la croissance, l&#39;adh&eacute;sion et la propagation cellulaire dans les 3 &eacute;chafaudages. Nos r&eacute;sultats pour SOD et CAT se sont av&eacute;r&eacute;s meilleurs pour les &eacute;chafaudages TiNbZrTa et TiAlV. L&#39;&eacute;chafaudage TiNb pr&eacute;sentait moins d&#39;activit&eacute; pour les deux enzymes. Malgr&eacute; les diff&eacute;rences entre les &eacute;chafaudages, il n&#39;y avait aucune diff&eacute;rence statistique (p&gt; 0,05). RUNX2 pr&eacute;sentait une expression &eacute;lev&eacute;e pour TiNbZrTa et TiAlV au jour 7 et pr&eacute;sentait des diff&eacute;rences statistiques uniquement pour TiNbZrTa par rapport au groupe t&eacute;moin (TiAlV jour 3). Au jour 14, tous les &eacute;chafaudages pr&eacute;sentaient une expression sup&eacute;rieure &agrave; la ligne de base et pr&eacute;sentaient des diff&eacute;rences statistiques par rapport au groupe t&eacute;moin. Il a &eacute;t&eacute; possible de conclure qu&#39;en ce qui concerne les enzymes antioxydantes, nous ne sommes pas en mesure de confirmer des diff&eacute;rences qui justifieraient le remplacement du TiAlV, mais l&#39;expression g&eacute;n&eacute;tique a montr&eacute; une meilleure capacit&eacute; de diff&eacute;renciation des cellules souches m&eacute;senchymateuses dans TiNbZrTa, ce qui en fait un bon choix pour les applications biom&eacute;dicales.</p> <div class="alert alert-info text-left"><b>Clause de non-responsabilit茅:</b> Ce r茅sum茅 a 茅t茅 traduit 脿 l'aide d'outils d'intelligence artificielle et n'a pas encore 茅t茅 r茅vis茅 ou v茅rifi茅.</div> <div class="nav social-icons"> <a class="nav-link w-auto">Partagez cet article</a> <a title="Cliquez ici" target="_blank" href="https://www.facebook.com/sharer.php?u=https://french.longdom.org/abstract/activity-of-the-antioxidant-enzymes-and-emrunx2em-expression-on-porous-titanium-alloy-scaffolds-105061.html" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="Cliquez ici" target="_blank" href="https://twitter.com/share?url=https://french.longdom.org/abstract/activity-of-the-antioxidant-enzymes-and-emrunx2em-expression-on-porous-titanium-alloy-scaffolds-105061.html" rel="noopener"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="Cliquez ici" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://french.longdom.org/abstract/activity-of-the-antioxidant-enzymes-and-emrunx2em-expression-on-porous-titanium-alloy-scaffolds-105061.html" rel="noopener"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link" title="Cliquez ici" target="_blank" href="https://plus.google.com/share?url=https://french.longdom.org/abstract/activity-of-the-antioxidant-enzymes-and-emrunx2em-expression-on-porous-titanium-alloy-scaffolds-105061.html" rel="noopener"><i class="fab fa-google-plus-g"></i></a> </div> </div> </div> </div> </section> <footer class="bg-blue-grey-900 py-3"> <div class="container"> <div class="row"> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Liens de contenu</h4> <ul class="list-unstyled footer-links font-size-3"> <li><a class="" href="https://french.longdom.org/privacy-policy.html" title="Cliquez ici">politique de confidentialit茅</a></li> <li><a class="" href="https://french.longdom.org/terms-conditions.html" title="Cliquez ici">termes et conditions</a></li> <li><a class="" href="https://french.longdom.org/authors-reviewers-editors.html" title="Cliquez ici">Auteurs, critiques et 茅diteur</a></li> </ul> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Contacter Longdom</h4> <p><strong>Groupe Longdom SA</strong><br /> Avenue Roger Vandendriessche,<br /> 18, 1150 Bruxelles, Belgique<br /> T茅l茅phone : +442038085340<br /> <strong>Courriel :</strong> <a class="white" href="mailto:info@longdom.org" title="Cliquez ici">info@longdom.org</a></p> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Connecter</h4> <nav class="nav nav-pills social-icons-footer flex-column a-pl-0"> <a href="https://www.facebook.com/longdompublisher" title="Cliquez ici" target="_blank" class="nav-link bg-facebook-hover"><i class="fab fa-facebook-f bg-facebook"></i></a> <a href="https://www.linkedin.com/company/longdom-publishing-sl/" title="Cliquez ici" target="_blank" class="nav-link bg-linkedin-hover"><i class="fab fa-linkedin-in bg-linkedin"></i></a> <a href="https://twitter.com/LongdomP" title="Cliquez ici" target="_blank" class="nav-link bg-twitter-hover"><i class="fab fa-twitter bg-twitter"></i></a> <a href="https://www.instagram.com/longdom_publisher/" title="Cliquez ici" target="_blank" class="nav-link bg-instagram-hover"><i class="fab fa-instagram bg-instagram"></i></a> </nav> </div> </div> <div class="row text-center"> <div class="col"> <p>droits d auteur &copy; 2024 <a href="https://french.longdom.org/" title="Cliquez ici" class="white">Longdom 脡ditions SL</a>.</p> </div> </div> </div> </footer> <!--========================== Scroll To Top ============================--> <a href="#0" class="cd-top js-cd-top">Top</a> <!-- Optional JavaScript --> <!-- jQuery first, then Popper.js, then Bootstrap JS --> <script src="https://code.jquery.com/jquery-3.3.1.min.js"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/popper.js/1.14.7/umd/popper.min.js"></script> <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/js/bootstrap.min.js"></script> <!--Get the app icon js--> <script> jQuery(function($) { $(window).scroll(function fix_element() { $('#target').css( $(window).scrollTop() > 100 ? 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