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class="cms-collection__column-inner"> <div class="cms-item cms-collection" data-fragment="730710"> <div id="aims+and+scope" class="cms-item cms-article" data-fragment="716922"> <h2>Aims and scope</h2> <div class="cms-article__body"> <p><em>Trials </em>encompasses all aspects of the performance and findings of randomized controlled trials in health. We publish articles on general trial methodology and research into trial processes, as well as study protocols and statistical analysis plans for randomized controlled trials, commentaries and traditional results papers - regardless of outcome or significance of findings.</p><p><a href="https://trialsjournal.biomedcentral.com/about" target="_blank" class="is-external">Read more</a></p> </div> </div> <div class="cms-item cms-collection" data-tabs="tabs" data-fragment="727392"> <h2 class="cms-collection__title">Articles</h2> <ul class="c-nav c-nav--tabs c-nav--fill u-mb-16" role="tablist"> <li role="presentation" class="c-nav__item"> <a class="c-nav__link is-active" href="#tab-1" aria-controls="tab-1" role="tab" data-toggle="tab" data-track="click" data-track-category="Recent" data-track-action="Clicked tab" >Recent</a> </li> <li role="presentation" class="c-nav__item"> <a class="c-nav__link" href="#tab-2" aria-controls="tab-2" role="tab" data-toggle="tab" data-track="click" data-track-category="Most accessed" data-track-action="Clicked tab" >Most accessed</a> </li> </ul> <div role="tabpanel" class="c-tab-content is-active" id="tab-1"> <div data-test="recent-articles"> <div data-track-component="Recent"> <div data-total="10622" data-test="search-content"> <ol class="c-listing"> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-024-08646-0" data-track="click||select_recent_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 0">Agile monitoring dashboard for clinical research studies</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Leslie Gardner, Peggy Bylund, Sarah Robbins, Emma Holler, Fereshtehossadat Shojaei, Fatemehalsadat Shojaei, Mark Seidman, Richard J. Holden, Nicole R. Fowler, Ben Zarzaur, Cristina Barboi and Malaz Boustani</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Methodology</span> <span itemprop="datePublished" data-test="published-on">29 November 2024</span> </div> </article> </li> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-024-08616-6" data-track="click||select_recent_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 1">A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate <em>Opisthorchis viverrini</em> and soil transmitted helminths in the Lower Mekong Basin</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Mary Lorraine Mationg, Archie C. A. Clements, Gail M. Williams, Matthew Kelly, Donald E. Stewart, Catherine A. Gordon, Kinley Wangdi, Sirikachorn Tangkawattana, Apiporn T. Suwannatrai, Vanathom Savathdy, Visal Khieu, Sangduan Wannachart, Suji Yoo O’Connor, Simon Forsyth, Sean Gannon, Peter Odermatt…</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Study protocol</span> <span itemprop="datePublished" data-test="published-on">28 November 2024</span> </div> </article> </li> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-024-08633-5" data-track="click||select_recent_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 2">Implementation and evaluation of a navigation program for people with cancer in old age and their family caregivers: study protocol for the EU NAVIGATE International Pragmatic Randomized Controlled Trial</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Tinne Smets, Lara Pivodic, Rose Miranda, Fien Van Campe, Chelsea Vinckier, Barbara Pesut, Wendy Duggleby, Andrew N. Davies, Amanda Lavan, Peter May, Barbara Gomes, Maja Furlan de Brito, Vitor Rodrigues, Katarzyna Szczerbińska, Violetta Kijowska, Ilona Barańska…</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Study protocol</span> <span itemprop="datePublished" data-test="published-on">27 November 2024</span> </div> </article> </li> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-024-08578-9" data-track="click||select_recent_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 3">Comparisons of efficacy and safety of 400 or 800 ml bacterial count fecal microbiota transplantation in the treatment of recurrent hepatic encephalopathy: a multicenter prospective randomized controlled trial in China</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Pengfei Zou, Yunjiao Bi, Zhaowei Tong, Tao Wu, Qiang Li, Kai Wang, Yuchen Fan, Dan Zhao, Xin Wang, Hui Shao, Haijun Huang, Suping Ma, Yunsong Qian, Guoqiang Zhang, Xiao Liu, Qiaofei Jin…</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Study protocol</span> <span itemprop="datePublished" data-test="published-on">27 November 2024</span> </div> </article> </li> <li class="u-position-relative"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-024-08636-2" data-track="click||select_recent_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 4">High-concentrated platelet-rich plasma (PRP) versus placebo in osteoarthritis in the thumb base: study protocol for an assessor-blinded randomized controlled trial</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Johanna von Kieseritzky and Maria Wilcke</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Study protocol</span> <span itemprop="datePublished" data-test="published-on">26 November 2024</span> </div> </article> </li> </ol> </div> </div> <div class="u-display-flex u-justify-content-space-between u-align-items-baseline u-flex-wrap"> <p class="u-text-sm u-mr-16 u-mb-8"> <a href="/articles/most-recent/rss.xml" class="u-display-flex u-align-items-center" target="_blank" rel="noopener" data-test="recent-articles-feed"> Most recent articles RSS <svg class="u-icon u-flex-static u-ml-8" width="11" height="11" aria-hidden="true" focusable="false"> <use xlink:href="#icon-rss"></use> </svg> </a> </p> <p> <a href="/articles" class="u-button" data-track="click_all_articles" data-track-context="recent articles list section on bmc journal homepages" data-track-category="Recent" data-track-action="Clicked view all articles link"> <span class="u-display-flex u-align-items-center"> View all articles <svg class="u-flex-static u-ml-8" width="12" height="12" aria-hidden="true" focusable="false"> <use xlink:href="#icon-chevron-right"></use> </svg> </span> </a> </p> </div> </div> </div> <div role="tabpanel" class="c-tab-content " id="tab-2"> <div data-test="most-accessed-articles"> <div data-track-component="Most accessed"> <div data-total="5" data-test="search-content"> <ol class="c-listing"> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 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protocol</span> <span itemprop="datePublished" data-test="published-on">27 July 2018</span> </div> <div> <div class="c-status-message c-status-message--info"> <svg class="c-status-message__icon c-status-message__icon--top u-icon u-flex-static u-mt-4" aria-hidden="true" focusable="false"> <use xlink:href="#icon-info"></use> </svg> <div data-test="flash-message"> <p data-test="relatedFromMessage"> The <a href="/articles/10.1186/s13063-018-2883-1"> Correction to this article</a> has been published in <em> Trials</em> 2018 <strong>19</strong>:488 </p> </div> </div> </div> </article> </li> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/1745-6215-12-106" data-track="click||select_most_accessed_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 1">Through the looking glass: understanding non-inferiority</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Jennifer Schumi and Janet T Wittes</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Review</span> <span itemprop="datePublished" data-test="published-on">3 May 2011</span> </div> </article> </li> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-020-04848-4" data-track="click||select_most_accessed_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 2">Oral corticosteroids for post-infectious cough in adults: study protocol for a double-blind randomized placebo-controlled trial in Swiss family practices (OSPIC trial)</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Christoph Merlo, Stefan Essig, D. Oana Brancati-Badarau, Jörg Daniel Leuppi, Benjamin Speich, Tobias E. Erlanger, Lars G. Hemkens and Andreas Zeller</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Study protocol</span> <span itemprop="datePublished" data-test="published-on">23 November 2020</span> </div> </article> </li> <li class="u-position-relative u-keyline"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/1745-6215-15-264" data-track="click||select_most_accessed_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 3">Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>M Dawn Teare, Munyaradzi Dimairo, Neil Shephard, Alex Hayman, Amy Whitehead and Stephen J Walters</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Research</span> <span itemprop="datePublished" data-test="published-on">3 July 2014</span> </div> </article> </li> <li class="u-position-relative"> <article class="c-listing__content" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="c-listing__title u-text-md u-text-normal" itemprop="name"> <a itemprop="url" href="/articles/10.1186/s13063-018-2470-5" data-track="click||select_most_accessed_article" data-track-context="journal homepage recent articles and most accessed articles tabbed article list section" data-track-action="Clicked article link" data-track-label="article 4">Assessment of clinical effect and treatment quality of immediate-release carvedilol-IR versus SLOW release carvedilol-SR in Heart Failure patients (SLOW-HF): study protocol for a randomized controlled trial</a> </h3> <p class="c-listing__authors u-mb-0" data-test="authors"><span class="u-visually-hidden">Authors: </span>Dong-Ju Choi, Chan Soon Park, Jin Joo Park, Hae-Young Lee, Seok-Min Kang, Byung-Su Yoo, Eun-Seok Jeon, Seok Keun Hong, Joon-Han Shin, Myung-A Kim, Dae-Gyun Park, Eung-Ju Kim, Soon-Jun Hong, Seok Yeon Kim and Jae-Joong Kim</p> <div class="c-listing__metadata u-text-sm"> <span><span class="u-visually-hidden">Content type: </span>Study protocol</span> <span itemprop="datePublished" data-test="published-on">13 February 2018</span> </div> <div> <div class="c-status-message c-status-message--info"> <svg class="c-status-message__icon c-status-message__icon--top u-icon u-flex-static u-mt-4" aria-hidden="true" focusable="false"> <use xlink:href="#icon-info"></use> </svg> <div data-test="flash-message"> <p data-test="relatedFromMessage"> The <a href="/articles/10.1186/s13063-022-06559-4"> Correction to this article</a> has been published in <em> Trials</em> 2022 <strong>23</strong>:594 </p> </div> </div> </div> </article> </li> </ol> </div> </div> <div class="u-display-flex u-justify-content-space-between u-align-items-baseline u-flex-wrap"> <p class="u-text-sm u-mr-16 u-mb-8"> <a href="/articles/most-accessed/rss.xml" class="u-display-flex u-align-items-center" target="_blank" rel="noopener" data-test="most-accessed-feed"> <span>Most accessed articles RSS</span> <svg class="u-icon u-flex-static u-ml-8" width="11" height="11" aria-hidden="true" focusable="false"> <use xlink:href="#icon-rss"></use> </svg> </a> </p> <p class="u-text-right"> <a href="/articles" class="u-button" data-track="click_all_articles" data-track-context="most accessed article list section on bmc journal homepages" data-track-category="Most accessed" data-track-action="Clicked view all articles link"> <span class="u-display-flex u-align-items-center"> View all articles <svg class="u-flex-static u-ml-8" width="16" height="16" aria-hidden="true" focusable="false"> <use 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href="//www.biomedcentral.com/collections/c/cs/covidtrials" target="_self">COVID-19 trial protocols</a></p><p><strong>Article collection</strong><br><a href="//www.biomedcentral.com/collections/c/ct/covidtrialsimpact" target="_self">Impact of COVID-19 on clinical trials</a></p><p><strong>Thematic series</strong><br><a href="https://www.biomedcentral.com/collections/pragmatictrials" target="_self" class="is-external">The future of pragmatic trials</a><br> Edited by Prof Marion Campbell and Prof Sandra Eldridge</p><p><strong>Thematic series</strong><br><a href="https://www.biomedcentral.com/collections/bigdatatrials" target="_self" class="is-external">Big data for randomized trials</a><br> Edited by Dr Lars Hemkens</p><p><strong>Article collection</strong><br><a href="https://www.biomedcentral.com/collections/randomizedtrialsamplesize" target="_blank" class="is-external">Sample size calculations and specifying the target difference for randomized trials</a></p><p><strong>Thematic series</strong><br><a href="https://www.biomedcentral.com/collections/trialmanagement" target="_blank" class="is-external">Building capacity for evidence informed trial management</a><br> Edited by Dr Roberta Littleford and Prof Shaun Treweek</p><p><a href="http://trialsjournal.biomedcentral.com/articles/collections" target="_self" class="is-external">View all article collections</a></p><p><br></p> </div> </div> <div class="cms-item c-media" data-fragment="16369658"> <div class="c-media__figure"> <div class="cms-item c-image-copyright" data-fragment="15473622"> <a href="https://www.altmetric.com/explorer/report/0de09523-fd87-4e8d-860a-96e2a43dcd28" > <img src="//media.springernature.com/lw900/springer-cms/rest/v1/content/15473622/data/v2" alt="New Content Item"/> </a> </div> </div> <div class="c-media__body"> <h2 class="c-media__title"> <a href="https://www.altmetric.com/explorer/report/0de09523-fd87-4e8d-860a-96e2a43dcd28">Trending articles</a> </h2> <p>Click here to view which articles have been shared the most in the last month!</p> </div> </div> <div class="cms-item cms-collection" data-fragment="18058740"> <a class="teaser-placement" href="https://blogs.biomedcentral.com/blog/topics/medical-evidence/">Read More</a> </div> <div class="cms-item c-media" data-fragment="15289144"> <div class="c-media__body"> <h2 class="c-media__title"> <a href="https://trialsjournal.biomedcentral.com/reviewer-acknowledgements">Thank you to our peer reviewers</a> </h2> <p>The editors and staff of <em>Trials </em>would like to warmly thank our peer reviewers whose comments have helped to shape the journal.</p> </div> </div> <div id="peer+review+mentoring" class="cms-item cms-article" data-fragment="15811252"> <h2>Peer review mentoring</h2> <div class="cms-article__body"> <p>The Editors endorse peer review mentoring of early career researchers. Find out more <a href="/about/peer-review-mentoring" target="_self">here</a></p> </div> </div> </div> </div> </div> <div class="cms-collection__column"> <div class="cms-collection__column-inner"> <div class="cms-item cms-collection" data-fragment="730712"> <div id="announcement%3A+we+are+recruiting+new+associate+editors" class="cms-item cms-article" data-fragment="16346734"> <h2>Announcement: we are recruiting new Associate Editors</h2> <div class="cms-article__body"> <p>We are recruiting new Associate Editors to join our international Editorial Board, helping to provide expertise on the design, conduct and reporting of trials in our journal.<br></p><p>Click <a href="/trials-associate-editor" target="_self">here</a> to find out more.</p> </div> </div> <div id="call-for-papers" class="cms-item cms-article" data-fragment="27660814"> <h2>Call-for-papers</h2> <div class="cms-article__body"> <p><a href="https://www.biomedcentral.com/collections/IEDI" target="_blank" class="is-external">Improving equity, diversity, and inclusion in randomised trials</a><br> Edited by Shaun Treweek (University of Aberdeen, United Kingdom), Kamlesh Khunti (University of Leicester, United Kingdom), Shoba Dawson (The University of Sheffield, United Kingdom) and Tianjing Li (University of Colorado Denver, United States of America)</p> </div> </div> <div id="call-for-papers" class="cms-item cms-article" data-fragment="27660812"> <h2>Call-for-papers</h2> <div class="cms-article__body"> <p><a href="https://www.biomedcentral.com/collections/LTIE" target="_blank" class="is-external">Long-term Impact of Educational Interventions on Critical Health Literacy in Secondary School Students</a><br> Edited by Shaun Treweek (University of Aberdeen, UK)</p> </div> </div> <div id="call-for-papers" class="cms-item cms-article" data-fragment="23928372"> <h2>Call-for-papers</h2> <div class="cms-article__body"> <p><a href="https://www.biomedcentral.com/collections/CART" target="_blank" class="is-external">The collection, analysis and reporting of adverse events in randomised controlled trials</a><br> Edited by Victoria Cornelius (Imperial College London, UK) and Rachel Phillips (Imperial College London, UK)</p> </div> </div> <div class="cms-item c-media" data-fragment="19121086"> <div class="c-media__body"> <h2 class="c-media__title"> <a href="https://www.biomedcentral.com/collections/interimdata">Call-for-papers: Case studies of experience with interim data and IDMCs in RCTs</a> </h2> <p>Edited by Prof Matthew Sydes (MRC Clinical Trials Unit at UCL)</p> </div> </div> <div class="cms-item cms-collection" id="in+review%3A+an+integrated+pre-print+service+for+trials" data-fragment="16971830"> <h2 class="cms-collection__title">In Review: an integrated pre-print service for Trials</h2> <a class="teaser-placement" href="https://goo.gl/kSA6BN"></a> <div id="pictures"> <div class="cms-item c-image-copyright" data-fragment="16971862"> <a href="https://goo.gl/kSA6BN" > <img src="//media.springernature.com/lw900/springer-cms/rest/v1/content/16971862/data/v1" alt="In Review at Trials"/> </a> </div> </div> <div class="cms-item" data-fragment="16971836"> <div> <div class="u-mb-16-at-xxs u-mb-16-at-xs"> <p>Trials, in partnership with Research Square, is now offering In Review, a service that allows authors to opt in to upload their manuscript to a free preprint platform when submitting to Springer Nature journals. This service allows authors to:</p><p>• Share their work with fellow researchers to read, comment on, and cite even before publication</p><p>• Showcase their work to funders and others with a citable DOI while it is still under review</p><p>• Track their manuscript - including seeing when reviewers are invited, and when reports are received</p> <a href="https://www.springernature.com/gp/authors/campaigns/in-review" class="u-button u-button--primary" data-test="teaser-button-link"> Read More </a> </div> </div> </div> </div> <div class="cms-item cms-collection" id="research+on+research+registry" data-fragment="23294286"> <h2 class="cms-collection__title">Research on Research registry</h2> <a class="teaser-placement" href="https://ror-hub.org/"></a> <div id="pictures"> <div class="cms-item c-image-copyright" data-fragment="23323720"> <a href="https://ror-hub.org/" > <img src="//media.springernature.com/lw900/springer-cms/rest/v1/content/23323720/data/v1" alt="New Content Item"/> </a> </div> </div> <div class="cms-item cms-article cleared" data-fragment="23294296"> <div class="cms-article__body cleared"> <p>Trials would like to encourage authors of research on research (also referred to as meta-research or science of science) to register their work with the Research on Research (RoR) registry and hub. The registry has been designed to increase transparency, sharing and collaboration in research to develop and improve research design, conduct or reporting. If you have registered with the RoR registry, please include the registry record URL within your submission.</p><p>For more information on the RoR registry, and to register your research, please visit <a href="https://urldefense.com/v3/__https:/eur03.safelinks.protection.outlook.com/?url=https*3A*2F*2Fror-hub.org*2F&data=05*7C01*7Cars*40ecs.soton.ac.uk*7C707fcc958a6746e2310008da698a0eed*7C4a5378f929f44d3ebe89669d03ada9d8*7C0*7C0*7C637938339277734007*7CUnknown*7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0*3D*7C3000*7C*7C*7C&sdata=xuO0kkXI6mEbKLvWMDJwKv8gqDUpXkbxw6A1E9LyZw0*3D&reserved=0__;JSUlJSUlJSUlJSUlJSUlJSUlJSU!!NLFGqXoFfo8MMQ!o3bf0TU6SEYF3WwvA_3KFgjbTHue3qmdkn_kxuAP_yj27kaynHJxNQ7-T35rZh8NsbYfWihARwK-NH5X9w5Ew5SW$" class="is-external">https://ror-hub.org/</a>.</p> </div> </div> </div> <div class="cms-item" data-fragment="19700512"> <h2>Link your publications with an ORCiD identifier</h2> <div> <div class="u-mb-16-at-xxs u-mb-16-at-xs"> <p>Trials would like to ask all authors to include their ORCiD identifier when submitting their work to Trials. An ORCiD (Open Researcher and Contributor ID) number uniquely attaches your identity to your research work, such as your articles and datasets. You can get your free personal identifier at <a href="https://ORCiD.org/register" class="is-external">https://ORCiD.org/register</a>.</p> <a href="https://www.biomedcentral.com/getpublished/orcid" class="u-button u-button--primary" data-test="teaser-button-link"> Read More </a> </div> </div> </div> <div id="submissions+on+complementary+and+alternative+medicine" class="cms-item cms-article" data-fragment="19398090"> <h2>Submissions on complementary and alternative medicine</h2> <div class="cms-article__body"> <p>As a journal dedicated to improve the reporting and publication of clinical trials, we aim to embrace all content that is relevant, including general methodology papers, and research into the trial processes, protocols and statistical analysis plan for randomized controlled trials, as well as traditional research and commentary papers. However, it requires an in-depth subject knowledge to properly evaluate papers on the topic of complementary and alternative medicine to assess the intervention, the design of the trials, as well as the primary and secondary outcomes. Hence we feel it’s better to refer authors of these papers to the journals that are more equipped with the expertise required.</p><p>As of <strong>1<sup>st</sup> September 2021</strong>, <em>Trials</em> will no longer be considering papers on the topic of complementary and alternative medicine. We recommend the below journals from the BMC family that can accommodate studies in this area, do please check each journal scope carefully before submitting:</p><p>・<a href="https://bmccomplementmedtherapies.biomedcentral.com/" class="is-external"><em>BMC Complementary Medicine and Therapies</em></a> (accepting study protocols)</p><p>・<a href="https://cmjournal.biomedcentral.com/" class="is-external"><em>Chinese Medicine</em></a></p><p>・<a href="https://nutritionj.biomedcentral.com/" class="is-external"><em>Nutrition Journal</em></a><em> </em>(accepting study protocols)</p><p>Submissions made after 1st September will be referred to Transfer Desk team who will help the authors select a proper destination for their manuscript.</p> </div> </div> <div class="cms-item" data-fragment="17556650"> <h2>Structured Study Protocols</h2> <div> <div class="u-mb-16-at-xxs u-mb-16-at-xs"> <p><em>Trials</em> is experimenting with a new way of structuring study protocols for randomised trials. The simple innovation is to include all 51 SPIRIT headings and item identifiers within the protocol itself. Readers will then benefit from the ability to search by item identifier, which are contained within curly brackets. This is not mandatory and we will continue to consider protocols submitted in other formats.<br /><br />We have created a template for this new format that contains both SPIRIT and Trials guidance in one place.</p> <a href="/submission-guidelines/preparing-your-manuscript/study-protocol/structured-study-protocol-template" class="u-button u-button--primary" data-test="teaser-button-link"> Read More </a> </div> </div> </div> <div class="cms-item"> <h2>Latest Tweets</h2> <div class="c-box c-box--borderless app-twitter-timeline" data-twitter-timeline> <a class="twitter-timeline" data-chrome="noheader" data-tweet-limit="3" href="http://twitter.com/MedicalEvidence">View Twitter timeline</a> <p class="u-mb-0 u-js-hide"> Your browser needs to have JavaScript enabled to view this timeline </p> </div> </div> </div> </div> </div> </div> </div> <aside class="u-hide u-js-show c-customer-satisfaction-input u-mt-24" data-customer-satisfaction-input="" data-customer-satisfaction-input-user-journeys="get prepared to publish, get published, discover relevant scholarly content" data-customer-satisfaction-input-additional-info="bmc test"> <div class="c-customer-satisfaction-input__container"> <form class="c-customer-satisfaction-input__form js-skip-validation"> <h3 class="c-customer-satisfaction-input__heading">How was your experience today?</h3> <div class="c-forms__fieldset"> <div class="c-forms__field c-forms__field--globalFormRadios"> <fieldset class="c-forms__fieldset c-forms__field c-forms__radios" id="customer-satisfaction-input-radios" name="customer-satisfaction-input-radios" invalid="" aria-invalid="true" aria-describedby="error-customer-satisfaction-input-radios" required="" aria-required="true" autocomplete="off"> <legend class="c-forms__label">Rating<span class="c-form__label--visually-hidden">. 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