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Search results for: Lisandro Pacheco-Lugo

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</div> </nav> </div> </header> <main> <div class="container mt-4"> <div class="row"> <div class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Lisandro Pacheco-Lugo"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 3</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Lisandro Pacheco-Lugo</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Knowledge Management: Why is So Difficult? From “A Good Idea” to Organizational Contribute</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lisandro%20Blas">Lisandro Blas</a>, <a href="https://publications.waset.org/abstracts/search?q=H%C3%A9ctor%20Tamanini"> Héctor Tamanini</a> </p> <p class="card-text"><strong>Abstract:</strong></p> From earliest 90 to now, no many companies or organization can “really” implement a knowledge management (KM) system that works (no only viewed from a measurement model, but in this continuity). Which are the reasons of that? Some of the reason maybe could be embedded in how KM is demanded (usefulness, priority, experts, a definition of KM) vs the importance and resources that the organizations afford (budget, responsible of a specific area of KM, intangibility). Many organizations “claim” the importance of Knowledge Management but thhese demands are not reflecting these claims in their future actions. With another’s tools or managements ideas the organizations put the economics and human resources to work. Why it´s not occur in KM? This paper tray to explain some of this reasons and tray to deal with this situations through a survey done in 2011 for a IAPG (Argentinean Institute from Oil & Gas) Congress. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=knowledge%20management%20into%20organizations" title="knowledge management into organizations">knowledge management into organizations</a>, <a href="https://publications.waset.org/abstracts/search?q=new%20perspectives" title=" new perspectives"> new perspectives</a>, <a href="https://publications.waset.org/abstracts/search?q=failure%20in%20implementation" title=" failure in implementation"> failure in implementation</a>, <a href="https://publications.waset.org/abstracts/search?q=claim" title=" claim"> claim</a> </p> <a href="https://publications.waset.org/abstracts/20745/knowledge-management-why-is-so-difficult-from-a-good-idea-to-organizational-contribute" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/20745.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">421</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Urinalysis by Surface-Enhanced Raman Spectroscopy on Gold Nanoparticles for Different Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leonardo%20C.%20Pacheco-Londo%C3%B1o">Leonardo C. Pacheco-Londoño</a>, <a href="https://publications.waset.org/abstracts/search?q=Nataly%20J.%20Galan-Freyle"> Nataly J. Galan-Freyle</a>, <a href="https://publications.waset.org/abstracts/search?q=Lisandro%20Pacheco-Lugo"> Lisandro Pacheco-Lugo</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20Acosta"> Antonio Acosta</a>, <a href="https://publications.waset.org/abstracts/search?q=Elkin%20Navarro"> Elkin Navarro</a>, <a href="https://publications.waset.org/abstracts/search?q=Gustavo%20Aroca-Mart%C3%ADnez"> Gustavo Aroca-Martínez</a>, <a href="https://publications.waset.org/abstracts/search?q=Karin%20Rond%C3%B3n-Payares"> Karin Rondón-Payares</a>, <a href="https://publications.waset.org/abstracts/search?q=Samuel%20P.%20Hern%C3%A1ndez-Rivera"> Samuel P. Hernández-Rivera</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In our Life Science Research Center of the University Simon Bolivar (LSRC), one of the focuses is the diagnosis and prognosis of different diseases; we have been implementing the use of gold nanoparticles (Au-NPs) for various biomedical applications. In this case, Au-NPs were used for Surface-Enhanced Raman Spectroscopy (SERS) in different diseases' diagnostics, such as Lupus Nephritis (LN), hypertension (H), preeclampsia (PC), and others. This methodology is proposed for the diagnosis of each disease. First, good signals of the different metabolites by SERS were obtained through a mixture of urine samples and Au-NPs. Second, PLS-DA models based on SERS spectra to discriminate each disease were able to differentiate between sick and healthy patients with different diseases. Finally, the sensibility and specificity for the different models were determined in the order of 0.9. On the other hand, a second methodology was developed using machine learning models from all data of the different diseases, and, as a result, a discriminant spectral map of the diseases was generated. These studies were possible thanks to joint research between two university research centers and two health sector entities, and the patient samples were treated with ethical rigor and their consent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SERS" title="SERS">SERS</a>, <a href="https://publications.waset.org/abstracts/search?q=Raman" title=" Raman"> Raman</a>, <a href="https://publications.waset.org/abstracts/search?q=PLS-DA" title=" PLS-DA"> PLS-DA</a>, <a href="https://publications.waset.org/abstracts/search?q=diseases" title=" diseases"> diseases</a> </p> <a href="https://publications.waset.org/abstracts/160183/urinalysis-by-surface-enhanced-raman-spectroscopy-on-gold-nanoparticles-for-different-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/160183.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">141</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Surface-Enhanced Raman Spectroscopy on Gold Nanoparticles in the Kidney Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leonardo%20C.%20Pacheco-Londo%C3%B1o">Leonardo C. Pacheco-Londoño</a>, <a href="https://publications.waset.org/abstracts/search?q=Nataly%20J%20Galan-Freyle"> Nataly J Galan-Freyle</a>, <a href="https://publications.waset.org/abstracts/search?q=Lisandro%20Pacheco-Lugo"> Lisandro Pacheco-Lugo</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20Acosta-Hoyos"> Antonio Acosta-Hoyos</a>, <a href="https://publications.waset.org/abstracts/search?q=Elkin%20Navarro"> Elkin Navarro</a>, <a href="https://publications.waset.org/abstracts/search?q=Gustavo%20Aroca-Martinez"> Gustavo Aroca-Martinez</a>, <a href="https://publications.waset.org/abstracts/search?q=Karin%20Rond%C3%B3n-Payares"> Karin Rondón-Payares</a>, <a href="https://publications.waset.org/abstracts/search?q=Alberto%20C.%20Espinosa-Garavito"> Alberto C. Espinosa-Garavito</a>, <a href="https://publications.waset.org/abstracts/search?q=Samuel%20P.%20Hern%C3%A1ndez-Rivera"> Samuel P. Hernández-Rivera</a> </p> <p class="card-text"><strong>Abstract:</strong></p> At the Life Science Research Center at Simon Bolivar University, a primary focus is the diagnosis of various diseases, and the use of gold nanoparticles (Au-NPs) in diverse biomedical applications is continually expanding. In the present study, Au-NPs were employed as substrates for Surface-Enhanced Raman Spectroscopy (SERS) aimed at diagnosing kidney diseases arising from Lupus Nephritis (LN), preeclampsia (PC), and Hypertension (H). Discrimination models were developed for distinguishing patients with and without kidney diseases based on the SERS signals from urine samples by partial least squares-discriminant analysis (PLS-DA). A comparative study of the Raman signals across the three conditions was conducted, leading to the identification of potential metabolite signals. Model performance was assessed through cross-validation and external validation, determining parameters like sensitivity and specificity. Additionally, a secondary analysis was performed using machine learning (ML) models, wherein different ML algorithms were evaluated for their efficiency. Models’ validation was carried out using cross-validation and external validation, and other parameters were determined, such as sensitivity and specificity; the models showed average values of 0.9 for both parameters. Additionally, it is not possible to highlight this collaborative effort involved two university research centers and two healthcare institutions, ensuring ethical treatment and informed consent of patient samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SERS" title="SERS">SERS</a>, <a href="https://publications.waset.org/abstracts/search?q=Raman" title=" Raman"> Raman</a>, <a href="https://publications.waset.org/abstracts/search?q=PLS-DA" title=" PLS-DA"> PLS-DA</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20diseases" title=" kidney diseases"> kidney diseases</a> </p> <a href="https://publications.waset.org/abstracts/174893/surface-enhanced-raman-spectroscopy-on-gold-nanoparticles-in-the-kidney-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174893.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">45</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">&copy; 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