Pharma Digital Transformation Solutions

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Contact a Thermo Fisher Scientific representative.</div> </div> </div> </a> </div> </div> </div> </div> <div class="navL1 me-0"> <a href="https://www.patheon.com/us/en/insights-resources/blog.html" class="l1Text" data-linkposition="topNavL1"> Blog </a> </div> </div> </div> </div> </div> </div> <div class="breadcrumbs-cmp sticky-top aem-GridColumn aem-GridColumn--default--12"> <div id="breadcrumbs-154697018" class="pt-2 pb-3 breadCrumbs header-breadcrumbs"> <div class="container-fluid container-lg"> <nav aria-label="breadcrumb"> <div class="breadcrumb mb-0 align-items-center"> <div class="breadcrumb-item "> <a href="https://www.patheon.com/us/en/home.html">Home</a> </div> <div class="breadcrumb-item "> <a href="https://www.patheon.com/us/en/innovative-solutions.html">Innovative solutions</a> </div> <div class="breadcrumb-item active" aria-current="page"> <div>Digital enablement</div> </div> </div> </nav> </div> <script type="application/ld+json">{ "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.patheon.com/us/en/home.html" }, { "@type": "ListItem", "position": 2, "name": "Innovative solutions", "item": "https://www.patheon.com/us/en/innovative-solutions.html" }, { "@type": "ListItem", "position": 3, "name": "Digital enablement", "item": "https://www.patheon.com/us/en/innovative-solutions/digital-enablement.html" }] }</script> </div> </div> </div> </div> <div class="custom-html-cmp aem-GridColumn aem-GridColumn--default--12"> <script> $('[data-bs-target="#contactForm"]').on('click', function(){ window.location.href = '/us/en/about-us/contact-us/contact-form.html'; }); </script> </div> </div> </div> </header> <div class="responsivegrid aem-GridColumn aem-GridColumn--default--12"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 "> <div class="cmp-hero aem-GridColumn aem-GridColumn--default--12"> <div id="hero" class="pb-5 pt-5 hero-no-hr "> <div class="container-fluid container-lg"> <h1 class="h1 d-inline-block " style="color:;">Digital transformation and enablement </h1> <h2 class="h2 d-block" style="color:;"> Improving the sponsor, patient, and provider experience </h2> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> </div> </div> </div> <style type="text/css"> .cmp-hero #hero h1 span::before { background-color: ; } #hero { min-height: 350px; } </style> <style type="text/css"> #hero { background-image: url('/content/dam/patheon/global/hero-images/Blue_Vial.png'); background-position: center center; } </style> </div> <div class="cmp-well aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--small--newline aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--12"> <div class="well " style="background-position-x: center;background-position-y: top;background-image: url('/content/dam/patheon/global/hero-images/Molecule.png');" id="Global-Team"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--xsmall--12 aem-Grid--default--12 aem-Grid--large--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--newline aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6 aem-GridColumn--large--12"> <div id="global-expertist" class="cmp-text list-style-bullets"> <p>The digital transformation known as Pharma 4.0 is revolutionizing process optimization and decision-making within the pharmaceutical industry—at every level and across the clinical development lifecycle and supply chain. At the same time, decentralized clinical trials are now taking a leading role in clinical research. While the approach is not new, the pandemic has increased the incentive for using decentralized trials for future drug development.<br /> </p> <p>We are responding with digital innovations that push the limits of efficiency, agility, and quality for our customers as we adopt networked systems, data analytics, and advanced automation. Customers will see an improved experience at every step. Activities are streamlined, from routine daily status checks or placing orders, to executing a global decentralized clinical trial or manufacturing a full product line. </p> </div> </div> <div class="custom-html-cmp aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--12"> <style type="text/css"> @media (max-width: 1199px) { #Global-Team { background-image:none !important; } } </style> </div> </div> </div> </div> <style type="text/css"> #Global-Team { border-radius: 0px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " id="well-517671420"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-key-takeaways aem-GridColumn aem-GridColumn--default--12"> <div class="takeaways-wrapper"> <div class="takeaway-card" style="color: #ED7700; border-color: #ED7700"> <i class="fak fa-globalbrand-digital-enablement icon"></i> <div class="main-text"></div> <div class="sub-text"><h5><b><span style="color: rgb(255,133,27);">77%</span></b></h5> <p class="p-claim">Digital tools such as mobile technologies, mobile HCPs, and mobile phones are used in 77% of current decentralized trials<sup>1</sup></p> </div> </div> <div class="takeaway-card" style="color: #ED7700; border-color: #ED7700"> <i class="fak fa-globalbrand-data icon"></i> <div class="main-text"></div> <div class="sub-text"><h5 style="text-align: center;"><b><span style="color: rgb(255,133,27);">60-70%</span></b></h5> <p class="p-claim">Sixty to 70% of molecules in clinical development have high permeability but poor solubility; predictive modeling can help</p> </div> </div> </div> </div> </div> </div> </div> <style type="text/css"> #well-517671420 { border-radius: 0px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " style="background-position-x: center;background-position-y: center;" id="well-1665075446"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="custom-html-cmp aem-GridColumn aem-GridColumn--default--12"> <hr> </div> </div> </div> </div> <style type="text/css"> #well-1665075446 { border-radius: 0px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " style="background-position-x: center;background-position-y: center;" id="well-696101944"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xlarge--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-df1c352320" class="cmp-text list-style-bullets"> <h3>Digital enablement solutions and capabilities </h3> </div> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-360448582"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-accordion aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="mysupply"> <div class="accordion-item"> <div class="accordion-header" id="heading-mysupply"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-mysupply" aria-expanded="true" aria-controls="collapse-mysupply"> <span> <span class="accordion-title">mysupply Platform</span><br/> <span class="accordion-subtitle">End-to-end digital supply chain platform for visibility and collaboration across the full product lifecycle</span> </span> </button> </div> <div id="collapse-mysupply" class="accordion-collapse collapse " aria-labelledby="heading-mysupply" data-bs-parent="#mysupply"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xlarge--12 "> <div class="cmp-container aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 equalizeHeights h-100" id="container-1861641814"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div id="text-557df0943f" class="cmp-text list-style-bullets"> <p>From day-to-day order management and batch tracking to monthly forecasting, our digital mysupply Platform provides timely visibility and real-time collaboration tools to enable more efficient ways of working. mysupply can help you mitigate risk and keep you informed of production status by highlighting where and when your attention is most needed. </p> </div> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--6"> <div class="cmp-container-inner my-3 " id="container-2120143132"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--6"> <div id="text-647adad2fc" class="cmp-text list-style-check"> <div><b> </b></div> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);"><b>Simple order management: </b>Skip the email and log on to the platform to submit new orders and track existing ones. </li> </ul> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);"><b>Process transparency: </b>Check the status of your batches throughout the process, including change requests, analytical results, quality deviations, and shipping.</li> </ul> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);"><b>Automated forecasting: </b>Avoid the manual forecasting and reviewing process by relying on a templated and digital forecast system.</li> </ul> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);"><b>Streamlined digital experience: </b>Stop digging through emails and files for information. mysupply offers one place to review everything you need. </li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-2120143132{ background-image: url(''); background-color: #F7F7F7; background-size: cover; background-position: center; min-height: px; } #container-2120143132 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-1861641814{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1861641814 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1604695197"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 "> </div> </div> <style type="text/css"> #container-1604695197{ background-image: url('/content/dam/patheon/global/site-images/digital-enablement/Storage_Distribution.png'); background-color: ; background-size: cover; background-position: center; min-height: 300px; } #container-1604695197 { border-radius: 6px; } </style> </div> <div class="text aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--12"> <div id="text-c86beda722" class="cmp-text list-style-bullets"> <p> </p> <p>The platform gives you the ability to view current order status and batches linked to those orders, as well as risks associated with batches and orders. It also allows users to input change requests. Use it to identify delays and proactively address critical alerts and traceability of products.</p> <p>What’s more, the mysupply Platform provides near real-time data sharing to enhance transparency, build trust, and encourage collaboration among stakeholders. </p> </div> </div> <div class="cmp-container aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-1855499649"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 "> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--3 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner m-3 equalizeHeights h-100" id="container-91995085"> <div class="aem-Grid aem-Grid--3 aem-Grid--default--3 aem-Grid--xsmall--12 "> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--3"> <div class="cmp-container-inner m-3 " id="container-1862988133"> <div class="aem-Grid aem-Grid--3 aem-Grid--xsmall--12 aem-Grid--default--3 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--3"> <div id="text-a2ddd2e09b" class="cmp-text list-style-bullets"> <p><span style="color: rgb(255,255,255);"><b>Forecasts</b></span></p> <p><span style="color: rgb(255,255,255);">Automated forecast entry and upload with status tracking to monitor progress. </span></p> </div> </div> </div> </div> <style type="text/css"> #container-1862988133{ background-image: url(''); 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} #resource_card-683333376.resource-card, .resource_card-683333376.resource-card { background-image: url('\2f content\2f dam\2fpatheon\2ftest-images\2fResourceCardBg.png'); background-size: cover; } #resource_card-683333376.resource-card:hover, .resource_card-683333376.resource-card:hover { cursor:pointer; } #resource_card-683333376.resource-card:before, .resource_card-683333376.resource-card:before { content: ""; width: 100%; height: 100%; display: block; position: absolute; background-color: rgba(191, 217, 248, .14); top: 0; left: 0; transition: .5s ease; opacity: 0; } #resource_card-683333376.resource-card:hover:before, .resource_card-683333376.resource-card:hover:before { opacity: 1; } </style></div> </div> </div> </div></div> </div> </div> <style type="text/css"> #container-268596741{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-268596741 { border-radius: px; } </style> </div> </div> </div> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-360448582{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-360448582 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-1808293258"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-accordion aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="decentralized-clinical-trials"> <div class="accordion-item"> <div class="accordion-header" id="heading-decentralized-clinical-trials"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-decentralized-clinical-trials" aria-expanded="true" aria-controls="collapse-decentralized-clinical-trials"> <span> <span class="accordion-title">Decentralized clinical trials</span><br/> <span class="accordion-subtitle"> Poised to play a major role in drug development now and into the future</span> </span> </button> </div> <div id="collapse-decentralized-clinical-trials" class="accordion-collapse collapse " aria-labelledby="heading-decentralized-clinical-trials" data-bs-parent="#decentralized-clinical-trials"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-container aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--12 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner my-3 " id="container-2511226"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner " id="container-1053482587"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div class="cmp-container-inner p-3 " id="container-563469402"> <div class="aem-Grid aem-Grid--6 aem-Grid--xsmall--12 aem-Grid--default--6 aem-Grid--xlarge--6 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--none aem-GridColumn--default--none aem-GridColumn--xlarge--12 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--xlarge--0 aem-GridColumn--offset--default--0"> <div id="text-84fe69c67b" class="cmp-text list-style-check"> <p style="color: rgb(38,34,98);"><b>Did you know?</b></p> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);" class="p-claim">Remote, virtual, or decentralized trials more than doubled from 2015 to 2019<sup>2</sup></li> <li style="color: rgb(38,34,98);" class="p-claim">9 out of 10 survey respondents expect COVID-19 to catalyze adoption of deccentralized trial strategies<sup>1 </sup></li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-563469402{ background-image: url(''); background-color: #F7F7F7; background-size: cover; background-position: center; min-height: px; } #container-563469402 { border-radius: px; } </style> </div> <div class="text aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div id="text-38e446e946" class="cmp-text list-style-bullets"> <p> </p> <p>Decentralized clinical trials eliminate the need for a patient to visit an investigator site to receive treatment. These trials were on the rise for years before COVID-19, but their success in keeping drug development programs on course during the pandemic won these studies a new leading role in mainstream clinical development and commercialization going forward.</p> <p>Sponsors are turning to an integrated supply chain solution known as direct-to-patient services to execute decentralized trial strategies. Direct-to-patient services allow patients to participate in clinical trials from their homes by providing them with study drugs and care where they live, using telemedicine and mobile or local healthcare providers. </p> </div> </div> </div> </div> <style type="text/css"> #container-1053482587{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1053482587 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--medium--newline aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1936002187"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--6 "> </div> </div> <style type="text/css"> #container-1936002187{ background-image: url('/content/dam/patheon/global/site-images/digital-enablement/Women_on_phone.png'); background-color: ; background-size: cover; background-position: center; min-height: 558px; } #container-1936002187 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-2511226{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-2511226 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--12"> <div class="cmp-container-inner p-3 " id="container-2093630427"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-ea68ac07b2" class="cmp-text list-style-check"> <ul style="color: rgb(38,34,98);"> <p><b><span style="color: rgb(38,34,98);">The direct-to-patient category includes:</span></b></p> <p><span style="color: rgb(38,34,98);"><b>Fully decentralized studies</b><span>, often called virtual or site-less trials. These studies bring the clinical trial to a patient’s home using a central, often virtual, coordinating facility. <span class="p-claim">More than 75% of current decentralized trials use mobile technologies.</span></span><sup>1</sup> These trials may also harness telehealth, in-home devices, sensors, and wearables, as well as digital therapeutics. The use of artificial intelligence (AI) and machine learning (ML) is also becoming more routine to facilitate diagnoses, patient stratification, and evidence generation.</span></p> <p><span style="color: rgb(38,34,98);"><b>Hybrid trials </b><span>incorporate some virtual elements into a site-based study. These studies often access a combination of mobile clinics and patient-reported outcomes.</span></span></p> </ul> </div> </div> </div> </div> <style type="text/css"> #container-2093630427{ background-image: url(''); background-color: #f7f7f7; background-size: cover; background-position: center; min-height: px; } #container-2093630427 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--12 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner my-3 " id="container-277977151"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--xlarge--12 "> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--none aem-GridColumn--default--none aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn--offset--xlarge--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--small--0 aem-GridColumn--default--4"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-639491489"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--6 aem-Grid--default--4 aem-Grid--xsmall--12 aem-Grid--xlarge--4 "> <div class="cmp-container aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--6 aem-GridColumn--default--4"> <div class="cmp-container-inner " id="container-1574943633"> <div class="aem-Grid aem-Grid--4 aem-Grid--default--4 aem-Grid--xsmall--4 "> <div class="cmp-icon-and-text aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--default--0 aem-GridColumn--default--4"><div class="icon_and_text_wrapper h-100 style-transparent-no-border" id="icon_and_text-1577481419"> <div class="icon_and_text_inner"> <div class="icon_and_text_icon"> <span class="fa-stack fa-2x"> <i class="fa fa-circle fa-stack-2x icon-background" style="--color:#262262;"></i> <i class="fas fa-handshake icon fa-stack-1x" style="--color:#FFFFFF;"></i> </span> </div> <div class="icon_and_text_text"> <p><span style="color: rgb(38,34,98);"><span style="color: rgb(38,34,98);"><span class="font-weight-light"><span style="color: rgb(38,34,98);"><b><span style="color: rgb(38,34,98);">Benefits for sponsors </span></b></span></span></span></span></p> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-1574943633{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1574943633 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--newline aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--default--4"> <div class="cmp-container-inner " id="container-1832007405"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--6 aem-Grid--xsmall--12 "> <div class="text aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0"> <div id="text-69f8d0e890" class="cmp-text list-style-bullets"> <ul> <li>Improved patient enrollment and participation</li> <li>Shorter trial timelines</li> <li>More diverse/representative patient populations</li> <li>Reduced cost</li> <li>Real-time data</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-1832007405{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1832007405 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-639491489{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-639491489 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--none aem-GridColumn--default--none aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn--offset--xlarge--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--small--0 aem-GridColumn--default--4"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1396319544"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--6 aem-Grid--default--4 aem-Grid--xsmall--12 aem-Grid--xlarge--4 "> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--newline aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--default--4"> <div class="cmp-container-inner " id="container-1555381062"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--6 aem-Grid--xsmall--12 "> <div class="cmp-icon-and-text aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--default--0 aem-GridColumn--small--6"><div class="icon_and_text_wrapper h-100 style-transparent-no-border" id="icon_and_text-1608304788"> <div class="icon_and_text_inner"> <div class="icon_and_text_icon"> <span class="fa-stack fa-2x"> <i class="fa fa-circle fa-stack-2x icon-background" style="--color:#262262;"></i> <i class="fas fa-building icon fa-stack-1x" style="--color:#FFFFFF;"></i> </span> </div> <div class="icon_and_text_text"> <p><span style="color: rgb(38,34,98);"><span style="color: rgb(38,34,98);"><span style="color: rgb(38,34,98);"><b><span style="color: rgb(38,34,98);">Benefits for investigator sites </span></b></span></span></span></p> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-1555381062{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1555381062 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--newline aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--default--4"> <div class="cmp-container-inner " id="container-705745628"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--6 aem-Grid--default--4 aem-Grid--xsmall--6 "> <div class="text aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--newline aem-GridColumn--xsmall--6 aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--default--4"> <div id="text-06ee92c81e" class="cmp-text list-style-bullets"> <ul> <li>Easier patient recruitment</li> <li>No need to store study drugs and ancillaries during the duration of a study</li> <li>Less administrative burden on site staff</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-705745628{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-705745628 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-1396319544{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1396319544 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--xlarge--none aem-GridColumn--default--none aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn--offset--xlarge--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--small--newline aem-GridColumn--offset--small--3 aem-GridColumn--default--4"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-315321206"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--6 aem-Grid--default--4 aem-Grid--xsmall--12 aem-Grid--xlarge--4 "> <div class="cmp-container aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--6 aem-GridColumn--default--4"> <div class="cmp-container-inner " id="container-860507140"> <div class="aem-Grid aem-Grid--4 aem-Grid--default--4 aem-Grid--xsmall--4 "> <div class="cmp-icon-and-text aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--default--0 aem-GridColumn--default--4"><div class="icon_and_text_wrapper h-100 style-transparent-no-border" id="icon_and_text-1767189738"> <div class="icon_and_text_inner"> <div class="icon_and_text_icon"> <span class="fa-stack fa-2x"> <i class="fa fa-circle fa-stack-2x icon-background" style="--color:#262262;"></i> <i class="fas fa-person-sign icon fa-stack-1x" style="--color:#FFFFFF;"></i> </span> </div> <div class="icon_and_text_text"> <p><b><span style="color: rgb(38,34,98);">Benefits for patients and caregivers </span></b></p> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-860507140{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-860507140 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--xlarge--4 aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--small--6 aem-GridColumn--default--4"> <div class="cmp-container-inner " id="container-629063150"> <div class="aem-Grid aem-Grid--4 aem-Grid--default--4 aem-Grid--xsmall--4 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--4"> <div id="text-55c2469e79" class="cmp-text list-style-bullets"> <ul> <li>Reduced time and travel burden, making easier to recruit and retain patients</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-629063150{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-629063150 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-315321206{ background-image: url(''); 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} </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 predictive-modeling-engineered-solutions-container " id="container-1626802579"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--medium--12 "> <div class="cmp-accordion aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="predictive-modeling"> <div class="accordion-item"> <div class="accordion-header" id="heading-predictive-modeling"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-predictive-modeling" aria-expanded="true" aria-controls="collapse-predictive-modeling"> <span> <span class="accordion-title">AI predictive modeling for drug development</span><br/> <span class="accordion-subtitle">Reduce the risks associated with trial-and-error experimental methods</span> </span> </button> </div> <div id="collapse-predictive-modeling" class="accordion-collapse collapse " aria-labelledby="heading-predictive-modeling" data-bs-parent="#predictive-modeling"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 "> <div class="cmp-container aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-1304507084"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner py-3 " id="container-876126246"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div id="text-4d17f254bf" class="cmp-text list-style-bullets"> <h3>Quadrant 2</h3> <h4>Predicting solubility and bioavailability enhancement</h4> <p>Our proprietary computational modeling program, Quadrant 2<a name="_Hlk158209959" id="_Hlk158209959"></a><sup>TM</sup> , analyzes your compound’s specific molecular structure and chemical characteristics, in combination with your unique target product profile. The platform is built on exclusive algorithms that integrate a range of computational methods, including quantum mechanics, molecular dynamics, quantitative structure-activity relationship (QSAR) modeling, ADMET (Absorption, Distribution, Metabolism, Elimination, Toxicity) studies, statistical analysis, and internally developed models.</p> <p>Quadrant 2 analyzes the molecular structure and the physical and chemical characteristics of a compound based on the following information:</p> </div> </div> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div class="cmp-container-inner p-3 " id="container-1379603304"> <div class="aem-Grid aem-Grid--6 aem-Grid--xsmall--12 aem-Grid--default--6 "> <div class="text aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--default--6"> <div id="text-a4b673fc23" class="cmp-text list-style-check"> <ul> <li style="color: rgb(38,34,98);">Active pharmaceutical ingredient (API) chemical structure</li> <li style="color: rgb(38,34,98);">Physicochemical properties</li> <li style="color: rgb(38,34,98);">Full-scale molecular modeling based on quantum and molecular dynamics simulations</li> <li style="color: rgb(38,34,98);">Exclusive excipient descriptor database developed by Patheon pharma services</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-1379603304{ background-image: url(''); background-color: #f7f7f7; background-size: cover; background-position: center; min-height: px; } #container-1379603304 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-876126246{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-876126246 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--newline aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0 aem-GridColumn--xsmall--hide"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-997692187"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--6 "> </div> </div> <style type="text/css"> #container-997692187{ background-image: url('/content/dam/patheon/global/site-images/digital-enablement/Large_Molecule_in_Vial.png'); background-color: ; background-size: cover; background-position: center; min-height: 500px; } #container-997692187 { border-radius: 6px; } </style> </div> </div> </div> <style type="text/css"> #container-1304507084{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1304507084 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner p-3 " id="container-1337754161"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-89b302f733" class="cmp-text list-style-check"> <p>With the individualized data of a compound, Quadrant 2’s predictive modeling capabilities allow it to:</p> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);">Identify the most suitable solubility enhancement technology and excipient combination, aligning with the clinical and business objectives of the development stage</li> <li style="color: rgb(38,34,98);">Discard solubility enhancement options that are less likely to be beneficial, significantly reducing the time and investment typically lost in trial-and-error experimentation</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-1337754161{ background-image: url(''); background-color: #F7F7F7; background-size: cover; background-position: center; min-height: px; } #container-1337754161 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner p-3 " id="container-380277501"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-d2e78ac6f0" class="cmp-text list-style-bullets"> <p>Quadrant 2 accurately identifies technologies for solubility enhancement with a 90% success rate and selects excipients with an 80% accuracy rate. Using the data provided through the Quadrant 2 computational model conserves valuable API in the early stages of development.</p> </div> </div> </div> </div> <style type="text/css"> #container-380277501{ background-image: url(''); background-color: #F7F7F7; background-size: cover; background-position: center; min-height: px; } #container-380277501 { border-radius: 0px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--medium--newline aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-951397900"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--xsmall--12 aem-Grid--default--12 aem-Grid--large--12 aem-Grid--xlarge--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--small--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--12"> <div id="text-c13a24c7f2" class="cmp-text list-style-bullets"> <h4>Helpful resources </h4> <p>Browse our resource library to learn more about Quadrant 2 and other digital modeling capabilties.</p> </div> </div> <div class="cmp-resource-card aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--xlarge--none aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xlarge--3 aem-GridColumn--offset--xlarge--0 aem-GridColumn--offset--default--0 aem-GridColumn--small--6 aem-GridColumn--offset--medium--0 aem-GridColumn--large--4 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--offset--small--0 aem-GridColumn--default--3 aem-GridColumn--medium--6"> <a href="https://www.patheon.com/us/en/insights-resources/fact-sheets/quadrant-2-predictive-platform-for-solubility-and-bioavailability-enhancement.html" target="_self"> <div class="resource-card resource_card-260817352" id="resource_card-260817352"> <div class="resource-card-body"> <div class="tag"> <i class="fak fa-patheon-whitepaper pad-right icon"></i> Whitepaper </div> <p class="resource-card-title"> <p>Quadrant 2 predictive platform for solubility and bioavailability enhancement </p> </p> <div class="cta-wrapper"> <span class="resource-card-cta"> Download </span> </div> </div> </div> </a> <style> #resource_card-260817352.resource-card, .resource_card-260817352.resource-card { min-height: 250px; 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background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1923405293 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--newline aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 " id="container-1338784725"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div id="text-381c0e6a9d" class="cmp-text list-style-bullets"> <p><b>Track and Trace digital portal</b></p> <p>Track all your shipments in one place.</p> </div> </div> <div class="image aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <link rel="stylesheet" href="/etc.clientlibs/multisitecommons/clientlibs/clientlib-image.min.css" type="text/css"> <script src="/etc.clientlibs/multisitecommons/clientlibs/clientlib-image.min.js"></script> <script src="/etc.clientlibs/multisitecommons/clientlibs/vendor/magnificpopup.min.js"></script> <div data-cmp-is="image" data-cmp-lazythreshold="0" data-cmp-src="/content/patheon/us/en/innovative-solutions/digital-enablement/_jcr_content/root/responsivegrid/well_1398968081_copy/container_123154231__1826932739/accordion/accordionparsys/container_copy_19535/image.coreimg{.width}.jpeg/1724183999518/trace-and-trace-digital-portal.jpeg" data-asset="/content/dam/patheon/ko_kr/global/site-images/clinical-trials/trace-and-trace-digital-portal.jpg" data-asset-id="d3d5cadd-5d2f-47eb-8e61-84629401e2c6" data-title="Track and Trace portal" id="image-39d547f0ad" class="cmp-image false " itemscope itemtype="http://schema.org/ImageObject"> <img src="/content/patheon/us/en/innovative-solutions/digital-enablement/_jcr_content/root/responsivegrid/well_1398968081_copy/container_123154231__1826932739/accordion/accordionparsys/container_copy_19535/image.coreimg.jpeg/1724183999518/trace-and-trace-digital-portal.jpeg" class="cmp-image__image false " itemprop="contentUrl" data-cmp-hook-image="image" alt="Track and Trace portal"/> </div> </div> </div> </div> <style type="text/css"> #container-1338784725{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1338784725 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 " id="container-316374514"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div id="text-ada048afbc" class="cmp-text list-style-bullets"> <p><b>Real-time sensors</b></p> <p>View your cold chain shipments using real-time temperature and location tracking.</p> </div> </div> <div class="image aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div data-cmp-is="image" data-cmp-lazythreshold="0" data-cmp-src="/content/patheon/us/en/innovative-solutions/digital-enablement/_jcr_content/root/responsivegrid/well_1398968081_copy/container_123154231__1826932739/accordion/accordionparsys/container_copy_19535_605978458/image.coreimg{.width}.jpeg/1724184092182/real-time-sensors-scaled.jpeg" data-asset="/content/dam/patheon/ko_kr/global/site-images/clinical-trials/real-time-sensors-scaled.jpg" data-asset-id="b40a7872-52af-4019-a82a-008846b02b1d" data-title="Real-time sensors dashboard for temperature and location tracking" id="image-8e248c5f44" class="cmp-image false " itemscope itemtype="http://schema.org/ImageObject"> <img src="/content/patheon/us/en/innovative-solutions/digital-enablement/_jcr_content/root/responsivegrid/well_1398968081_copy/container_123154231__1826932739/accordion/accordionparsys/container_copy_19535_605978458/image.coreimg.jpeg/1724184092182/real-time-sensors-scaled.jpeg" class="cmp-image__image false " itemprop="contentUrl" data-cmp-hook-image="image" alt="Real-time sensors dashboard for temperature and location tracking"/> </div> </div> </div> </div> <style type="text/css"> #container-316374514{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-316374514 { border-radius: px; } </style> </div> </div> </div> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-331718525{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-331718525 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-530512298"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--medium--12 "> <div class="cmp-accordion aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="smart-packaging"> <div class="accordion-item"> <div class="accordion-header" id="heading-smart-packaging"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-smart-packaging" aria-expanded="true" aria-controls="collapse-smart-packaging"> <span> <span class="accordion-title">Smart Packaging</span><br/> <span class="accordion-subtitle">Technology to improve medication adherence</span> </span> </button> </div> <div id="collapse-smart-packaging" class="accordion-collapse collapse " aria-labelledby="heading-smart-packaging" data-bs-parent="#smart-packaging"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 " id="container-716733370"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div id="text-edac9ff72b" class="cmp-text list-style-bullets"> <p>Smart packaging uses microcircuits to passively measure dosing data and connects to the cloud via technology such as the patient’s smartphone. Cloud-based platforms then utilize sophisticated algorithms to analyze patient dosing behaviors and identify irregularities, enabling site staff to intervene and help patients adhere to their prescribed regimen.</p> <p>Smart packaging for medication adherence provides a rich and reliable data set, enhancing the understanding of patient dosing patterns, which makes it applicable to most clinical trial designs. It is particularly beneficial for clinical trials that:</p> <ul> <li>Require precise tracking of the intervals between doses</li> <li>Have complex dosing regimens</li> <li>Last longer than one year</li> <li>Include long intervals between visits to clinical sites (decentralized clinical trials)</li> </ul> </div> </div> <div class="cmp-button aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div id="button-651190631" class="btn-wrapper"> <a class=" btn btn-style-primary icon-placement-left " href="https://www.patheon.com/us/en/insights-resources/blog/smart-packaging-advances-clinical-trial-adherence-and-accuracy.html" role="button" target="_self"> Learn more about smart packaging </a> </div> <style> #button-651190631 .btn-style-quickLink { border-left: 6px solid #1E8AE7; } #button-651190631 { padding-right:0px; padding-left:0px; } </style> </div> </div> </div> <style type="text/css"> #container-716733370{ background-image: url(''); background-color: ; 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Rigorous setup and planning help to define clear protocols, select appropriate participants, and establish reliable methodologies — ultimately contributing to the integrity of the clinical trial’s results.</p> <p>Thermo Fisher Scientific’s Trial Setup and Planning (TSP) system is a comprehensive solution designed to optimize your study while empowering you to achieve greater efficiency, accuracy, and success in your clinical trial planning and execution.</p> <p>Some key benefits that our TSP solution provides include:</p> <ul> <li>Robust demand planning and supply coordination</li> <li>Strategic study design and supply chain optimization</li> <li>Access to clinical trial expertise and support</li> <li>Real-time visibility into study dynamics</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-2039598307{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-2039598307 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 " id="container-1911261195"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-html5-video aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div class="html5-video-cmp-container controls-enabled"> <video class="html5videoobj " width="100%" data-autoplay="false" controls="true" controlslist="nodownload" disableremoteplayback="true" x-webkit-airplay="deny" poster="/content/dam/temp_patheon/library/thumbnails/clinical-trial-services/VideoG_clinical_trial_services.png" playsinline data-src="/content/dam/temp_patheon/library/resources/videos/video-setup-and-planning-tsp-solution-for-clinical-trials1.mp4" id="html5video-1173826697"> <source/> </video> </div> </div> </div> </div> <style type="text/css"> #container-1911261195{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1911261195 { border-radius: px; } </style> </div> </div> </div> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-582101843{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-582101843 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-103836257"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--medium--12 "> <div class="cmp-accordion aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="predictive-in-silico-modeling"> <div class="accordion-item"> <div class="accordion-header" id="heading-predictive-in-silico-modeling"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-predictive-in-silico-modeling" aria-expanded="true" aria-controls="collapse-predictive-in-silico-modeling"> <span> <span class="accordion-title">Predictive in silico modeling (Engineered Solutions)</span><br/> <span class="accordion-subtitle">Transforming drug development from start to finish</span> </span> </button> </div> <div id="collapse-predictive-in-silico-modeling" class="accordion-collapse collapse " aria-labelledby="heading-predictive-in-silico-modeling" data-bs-parent="#predictive-in-silico-modeling"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 " id="container-1447697649"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div id="text-158ee52b0f" class="cmp-text list-style-bullets"> <p>In silico modeling technologies are transforming drug development and manufacturing by enhancing efficiency and accuracy, enabling innovation. Powered by artificial intelligence, machine learning, bioinformatics, molecular dynamics simulations, and systems biology, these tools accelerate the development of new drugs, optimize formulations, ensure manufacturing quality, and streamline regulatory processes, all while potentially reducing costs and time to market.</p> <p>Thermo Fisher Scientific's advanced computational and digital modeling capabilities, collectively known as Engineered Solutions, support a comprehensive approach to drug product development by enabling smarter decisions through a deeper understanding of different product parameters.</p> <p>Utilizing both proprietary and industry-standard technologies, these solutions are key in de-risking and accelerating every phase of drug development. Specific applications include:</p> <ul> <li><a href="https://www.patheon.com/us/en/our-capabilities/small-molecule/oral-solid-dose/in-silico-modeling.html#solubility-enhancement-ai-machine-learning-predictive-modeling">AI and machine learning-enabled predictive modeling for solubility and bioavailability enhancement</a></li> <li>Accelerated stability modeling for shelf life and packaging determination</li> <li>Materials science, compaction simulation, and process modeling</li> <li><a href="https://www.patheon.com/us/en/our-capabilities/small-molecule/oral-solid-dose/in-silico-modeling.html#adme-pk-modeling">ADME-PK modeling to predict the effect of API physiochemical traits on its pharmacokinetics</a></li> </ul> </div> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner me-lg-3 me-md-0 " id="container-952557905"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0 aem-GridColumn--medium--6"> <div id="text-c642b7c9ca" class="cmp-text list-style-bullets"> <p><b>Advantages of Thermo Fisher Scientific’s Engineered Solutions:</b></p> <ul> <li>Mitigate development risks and reduce experimental failures</li> <li>Accelerate development timelines</li> <li>Lower overall costs</li> <li>Conserve valuable API resources</li> <li>Empower informed decision-making and rational drug design</li> <li>Reduce reliance on animal testing</li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-952557905{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-952557905 { border-radius: px; } </style> </div> <div class="cmp-button aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--12"> <div id="button-792074603" class="btn-wrapper"> <a class=" btn btn-style-primary icon-placement-left " href="https://www.patheon.com/us/en/our-capabilities/small-molecule/oral-solid-dose/in-silico-modeling.html" role="button" target="_self"> Learn more about each in silico modeling option </a> </div> <style> #button-792074603 .btn-style-quickLink { border-left: 6px solid #1E8AE7; } #button-792074603 { padding-right:0px; padding-left:0px; } </style> </div> </div> </div> <style type="text/css"> #container-1447697649{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1447697649 { border-radius: px; } </style> </div> </div> </div> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-103836257{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-103836257 { border-radius: px; } </style> </div> <div class="custom-html-cmp aem-GridColumn--xlarge--none aem-GridColumn--default--none aem-GridColumn--xlarge--12 aem-GridColumn aem-GridColumn--default--11 aem-GridColumn--offset--xlarge--0 aem-GridColumn--offset--default--0"> <div style='padding-top: 10px;padding-bottom: 33px;'> <hr style='margin:0;'> </div> </div> <div class="custom-html-cmp aem-GridColumn aem-GridColumn--default--12"> <details> <summary><b>View references</b></summary> <div>1. Berlanga H, Shea K, Zweig L (2021) EU Clinical Trial Regulation 2022 – Impact on regulatory, labeling & QP. Thermo Fisher Scientific.</div> <div>2. Lorck CA (2021) Annex VI to Clinical Trial Regulation 536/2014: risk assessment-based concept of an interim* solution on expiry date labelling of the immediate packaging of Investigational Medicinal Products (IMPs). European Federation of Pharmaceutical Industries and Associations.</div> <div>3. TransCelerate Biopharma Inc. eLabels (website), n.d.</div> <div>4. Wang B (2020) Pharma companies launch initiative to push for e-labeling. 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