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Synthesis of Metal Curcumin Complexes with Iron(III) and Manganese(II): The Effects on Alzheimer's Disease
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<div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 87351</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Synthesis of Metal Curcumin Complexes with Iron(III) and Manganese(II): The Effects on Alzheimer's Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Emel%20Yildiz">Emel Yildiz</a>, <a href="https://publications.waset.org/abstracts/search?q=Nurcan%20Bi%C3%A7er"> Nurcan Bi莽er</a>, <a href="https://publications.waset.org/abstracts/search?q=Fazilet%20Aksu"> Fazilet Aksu</a>, <a href="https://publications.waset.org/abstracts/search?q=Arash%20Alizadeh%20Yegani"> Arash Alizadeh Yegani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Plants provide the wealth of bioactive compounds, which exert a substantial strategy for the treatment of neurological disorders such as Alzheimer's disease. Recently, a lot of studies have explored the medicinal properties of curcumin, including antitumoral, antimicrobial, anti-inflammatory, antioxidant, antiviral, and anti-Alzheimer's disease effects. Metal complexes of curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) were synthesized with Mn(II) and Fe(III). The structures of synthesized metal complexes have been characterized by using spectroscopic and analytic methods such as elemental analysis, magnetic susceptibility, FT-IR, AAS, TG and argentometric titration. It was determined that the complexes have octahedral geometry. The effects of the metal complexes on the disorder of memory, which is an important symptom of Alzheimer's Disease were studied on lab rats with Plus-Maze Tests at Behavioral Pharmacology Laboratory. <iframe src="https://publications.waset.org/abstracts/60623.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=curcumin" title="curcumin">curcumin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mn%28II%29" title=" Mn(II)"> Mn(II)</a>, <a href="https://publications.waset.org/abstracts/search?q=Fe%28III%29" title=" Fe(III)"> Fe(III)</a>, <a href="https://publications.waset.org/abstracts/search?q=Alzheimer%20disease" title=" Alzheimer disease"> Alzheimer disease</a>, <a href="https://publications.waset.org/abstracts/search?q=beta%20amyloid%2025-35" title=" beta amyloid 25-35"> beta amyloid 25-35</a> </p> <a href="https://publications.waset.org/abstracts/60623/synthesis-of-metal-curcumin-complexes-with-ironiii-and-manganeseii-the-effects-on-alzheimers-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60623.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">301</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> 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