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碘海醇注射液 其它药品制剂价格-采购批发-供应商-CPHI制药在线
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href="/zt/companycenter/userservice.html" target="_blank">我要推广 </a> </div> </div> <div style="clear: both"></div> </div> <div class="zy_top zy-top_bottom"> <div class="zhiyao_nav_all contain"> <div class="visibleBox"> <div class="cont_l"> <div class="c_l_top"> <i class="iconfont icon-caidan"></i> 产品分类导航 </div> <div class="c_l_list"> <ul> <li> <span> <a href="/Products/list-htm-catid-4.html"> 原料药</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-4.html" target="_blank">原料药</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-5.html"> 维生素类</a> <a href="/Products/list-htm-catid-6.html"> 四环素类</a> <a href="/Products/list-htm-catid-7.html"> 青霉素类</a> <a href="/Products/list-htm-catid-8.html"> 头孢菌素类</a> <a href="/Products/list-htm-catid-9.html"> 激素类</a> <a href="/Products/list-htm-catid-10.html"> 氨基酸及其衍生物</a> <a href="/Products/list-htm-catid-11.html"> 氨基糖苷类</a> <a href="/Products/list-htm-catid-12.html"> 大环内酯类</a> <a href="/Products/list-htm-catid-13.html"> 磺胺类</a> <a href="/Products/list-htm-catid-14.html"> 氯霉素类</a> <a href="/Products/list-htm-catid-15.html"> 林可霉素类</a> <a href="/Products/list-htm-catid-16.html"> 呼吸系统用药</a> <a href="/Products/list-htm-catid-17.html"> 解热镇痛药</a> <a href="/Products/list-htm-catid-18.html"> 消化系统用药</a> <a href="/Products/list-htm-catid-19.html"> 心血管系统用药</a> <a href="/Products/list-htm-catid-20.html"> 中枢神经系统用药</a> <a href="/Products/list-htm-catid-21.html"> 麻醉用药</a> <a href="/Products/list-htm-catid-22.html"> 其他抗感染类</a> <a href="/Products/list-htm-catid-23.html"> 抗寄生虫病药</a> <a href="/Products/list-htm-catid-24.html"> 其他西药原料</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-25.html"> 中间体</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-25.html" target="_blank">中间体</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-26.html"> 医药中间体</a> <a href="/Products/list-htm-catid-27.html"> 农药中间体</a> <a href="/Products/list-htm-catid-28.html"> 其他中间体</a> <a href="/Products/list-htm-catid-355.html"> 精细化工</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-29.html"> 生物制品</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-29.html" target="_blank">生物制品</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-30.html"> 试剂</a> <a href="/Products/list-htm-catid-63.html"> 生物技术服务</a> <a href="/Products/list-htm-catid-665.html"> 生物制剂</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-75.html"> 天然提取物</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-75.html" target="_blank">天然提取物</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-76.html"> 植物提取物</a> <a href="/Products/list-htm-catid-77.html"> 动物提取物</a> <a href="/Products/list-htm-catid-646.html"> 微生物提取物</a> <a href="/Products/list-htm-catid-671.html"> 功能性食品原料</a> <a href="/Products/list-htm-catid-672.html"> 食品、饮料原料</a> <a href="/Products/list-htm-catid-673.html"> 保健品原料</a> <a href="/Products/list-htm-catid-674.html"> 膳食补充剂</a> <a href="/Products/list-htm-catid-675.html"> 中药原料</a> <a href="/Products/list-htm-catid-676.html"> 美容化妆品原料</a> <a href="/Products/list-htm-catid-940.html"> 其他天然提取物</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-78.html"> 药品制剂</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-78.html" target="_blank">药品制剂</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-79.html"> 抗肿瘤制剂</a> <a href="/Products/list-htm-catid-80.html"> 抗寄生虫制剂</a> <a href="/Products/list-htm-catid-81.html"> 抗过敏用制剂</a> <a href="/Products/list-htm-catid-82.html"> 抗菌药与抗病毒药制剂</a> <a href="/Products/list-htm-catid-83.html"> 抗结核及麻风制剂</a> <a href="/Products/list-htm-catid-84.html"> 皮肤科制剂</a> <a href="/Products/list-htm-catid-85.html"> 五官科制剂</a> <a href="/Products/list-htm-catid-86.html"> 消化系统制剂</a> <a href="/Products/list-htm-catid-87.html"> 呼吸系统制剂</a> <a href="/Products/list-htm-catid-88.html"> 循环系统制剂</a> <a href="/Products/list-htm-catid-89.html"> 神经系统类制剂</a> <a href="/Products/list-htm-catid-90.html"> 血液系统药制剂</a> <a href="/Products/list-htm-catid-91.html"> 泌尿与生殖系统制剂</a> <a href="/Products/list-htm-catid-93.html"> 调节免疫功能制剂</a> <a href="/Products/list-htm-catid-94.html"> 调节水、电解质及酸碱平衡制剂</a> <a href="/Products/list-htm-catid-95.html"> 维生素、矿物质与氨基酸类制剂</a> <a href="/Products/list-htm-catid-96.html"> 酶类及其它生化制剂</a> <a href="/Products/list-htm-catid-97.html"> 解热镇痛类制剂</a> <a href="/Products/list-htm-catid-98.html"> 滋补营养药</a> <a href="/Products/list-htm-catid-99.html"> 有关激素类药</a> <a href="/Products/list-htm-catid-100.html"> 内分泌及代谢类制剂</a> <a href="/Products/list-htm-catid-101.html"> 清热解毒制剂</a> <a href="/Products/list-htm-catid-102.html"> 心脑血管类制剂</a> <a href="/Products/list-htm-catid-103.html"> 其它药品制剂</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-104.html"> 药用辅料</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-104.html" target="_blank">药用辅料</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-105.html"> 赋形剂</a> <a href="/Products/list-htm-catid-106.html"> 崩解剂</a> <a href="/Products/list-htm-catid-107.html"> 润滑剂</a> <a href="/Products/list-htm-catid-108.html"> 助流剂</a> <a href="/Products/list-htm-catid-109.html"> 包衣材料</a> <a href="/Products/list-htm-catid-110.html"> 增塑剂</a> <a href="/Products/list-htm-catid-111.html"> 肠溶材料</a> <a href="/Products/list-htm-catid-112.html"> 表面活性剂</a> <a href="/Products/list-htm-catid-113.html"> 溶媒</a> <a href="/Products/list-htm-catid-114.html"> 抗氧剂</a> <a href="/Products/list-htm-catid-115.html"> 遮光剂</a> <a href="/Products/list-htm-catid-116.html"> 矫味剂</a> <a href="/Products/list-htm-catid-117.html"> 甜味剂</a> <a href="/Products/list-htm-catid-118.html"> 香精</a> <a href="/Products/list-htm-catid-119.html"> 着色剂</a> <a href="/Products/list-htm-catid-120.html"> 促透剂</a> <a href="/Products/list-htm-catid-121.html"> 助滤剂</a> <a href="/Products/list-htm-catid-122.html"> 澄清剂</a> <a href="/Products/list-htm-catid-123.html"> 防腐剂</a> <a href="/Products/list-htm-catid-124.html"> 稳定剂</a> <a href="/Products/list-htm-catid-125.html"> ＰＨ调节剂</a> <a href="/Products/list-htm-catid-126.html"> 催化剂</a> <a href="/Products/list-htm-catid-127.html"> 其他药用辅料</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-128.html"> 合同外包、定制服务及咨询</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-128.html" target="_blank">合同外包、定制服务及咨询</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-129.html"> 合同研发外包</a> <a href="/Products/list-htm-catid-130.html"> 合同生产外包</a> <a href="/Products/list-htm-catid-131.html"> 咨询与服务</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-162.html"> 原料药设备</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-162.html" target="_blank">原料药设备</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-163.html"> 反应设备</a> <a href="/Products/list-htm-catid-164.html"> 干燥设备</a> <a href="/Products/list-htm-catid-165.html"> 结晶设备</a> <a href="/Products/list-htm-catid-167.html"> 萃取设备</a> <a href="/Products/list-htm-catid-168.html"> 换热器</a> <a href="/Products/list-htm-catid-169.html"> 储存设备</a> <a href="/Products/list-htm-catid-170.html"> 过滤分离</a> <a href="/Products/list-htm-catid-171.html"> 蒸发设备</a> <a href="/Products/list-htm-catid-172.html"> 蒸馏设备</a> <a href="/Products/list-htm-catid-173.html"> 筛分机械</a> <a href="/Products/list-htm-catid-174.html"> 灭菌设备</a> <a href="/Products/list-htm-catid-175.html"> 压滤设备</a> <a href="/Products/list-htm-catid-176.html"> 均质机</a> <a href="/Products/list-htm-catid-177.html"> 其它原料药设备</a> <a href="/Products/list-htm-catid-950.html"> 发酵设备</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-178.html"> 制剂设备</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-178.html" target="_blank">制剂设备</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-204.html"> 混合设备</a> <a href="/Products/list-htm-catid-951.html"> 颗粒设备</a> <a href="/Products/list-htm-catid-957.html"> 片剂设备</a> <a href="/Products/list-htm-catid-960.html"> 胶囊剂设备</a> <a href="/Products/list-htm-catid-964.html"> 粉碎设备</a> <a href="/Products/list-htm-catid-969.html"> 液体制剂设备</a> <a href="/Products/list-htm-catid-971.html"> 生物制药设备</a> <a href="/Products/list-htm-catid-980.html"> 其他制剂机械</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> 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href="/Products/list-htm-catid-1016.html"> 其它环保设备</a> </div> <div class="list_list_img"> </div> </div> </li> </ul> </div> </div> </div> <div class="cont_menu_second" id="cont_menu"> <a href="/" class="">首页 <div></div> </a> <a href="/Products/" class="active"> 产品 <div></div> </a> <a href="/suppliers/" class=""> 供应商 <div></div> </a> <a href="/buy/" class=""> 采购通 <div></div> </a> <a href="/news/" class=""> 资讯 <div></div> </a> <a href="/meeting/" class=""> 会展活动 <div></div> </a> <a class="exhibiton_menu" onmousemove="showEx()" onmouseleave="closeEx()" href="javascript:void(0)">CPHI & PMEC China展 <div></div> </a> </div> <div class="exhibition" onmouseleave="closeEx()" onmouseenter="showEx()" style="height: max-content;"> <p><a href="https://www.cphi-china.cn/" target="_blank">CPHI China</a></p> <p><a href="https://www.pmecchina.com/" target="_blank">PMEC China</a></p> <p><a href="https://www.cphi-china.cn/shenzhen/" target="_blank">CPHI & PMEC 深圳展</a></p> </div> </div> </div> <div class="outer"> <div class="center"> <div class="link"> <a href="/">首页<i class="iconfont icon-xiangyoujiantou"></i></a> <a href="/Products/">制药产品大全 <i class="iconfont icon-xiangyoujiantou"></i></a> <a href="/Products/list-htm-catid-78.html">药品制剂 <i class="iconfont icon-xiangyoujiantou"></i></a> <a href="javascript:;">碘海醇注射液</a> </div> <div class="d-flex-between"> <div class="product-left"> <div class="product-card"> <div class="product-card-left"> <div class="goodsImg"> <div class="swiper-container" id="productSwiperTop"> <div class="swiper-wrapper"> <div class="swiper-slide"> <img src="https://cimg.cphi.cn/img_Cphi_cn/Product/2019_04/Mimg_1904010227137464.jpg!250" alt="碘海醇注射液"> </div> </div> </div> <div class="goodsImg-tool"></div> </div> <div class="swiper-container" id="productSwiperBottom"> <div class="swiper-wrapper"> <div class="swiper-slide"> <img src="https://cimg.cphi.cn/img_Cphi_cn/Product/2019_04/Mimg_1904010227137464.jpg!250" alt="碘海醇注射液"> </div> </div> </div> <div class="big-show"> <div class="bigitem"> <img src="https://cimg.cphi.cn/img_Cphi_cn/Product/2019_04/Mimg_1904010227137464.jpg" alt="碘海醇注射液"> </div> </div> </div> <div class="product-card-right"> <div> <h1 class="product-name">碘海醇注射液</h1> </div> <div style="padding-left: 6px"> <div class="product-info" style="color: #999999;"> <span>更新时间：</span>2019-04-01 </div> <br> <div class="product-info price"><span>价格：</span> <label>面议</label> </div> <div class="product-info"> <span>地区：</span> 宁波 </div> <div class="product-info"> <span>是否提供样品：</span> 否 </div> </div> <div class="product-btn inquiry" data-id="304516">立即询盘</div> <div class="product-btm-btn"> <div class="product-btm-btn2 cancel_xin" data-id="304516" style="display: none" ><i class="iconfont icon-xin saved"></i> 取消 </div> <div class="product-btm-btn2 xin_button" data-id="304516" ><i class="iconfont icon-xin"></i> 收藏 </div> </div> </div> </div> <div class="product-info-card"> <div class="product-info-card-name"> 产品详情 </div> <div class="product-info-cont"> <div class="product-info"> <span>主要销售市场：</span> 北美洲,中/南美洲,西欧,东欧,大洋洲,亚洲,中东,非洲 </div> </div> <div class="product-info-bottom"> <div>产品描述：</div> <div class="desc-content"><div style="margin-left:auto"> <div> <div> <div> <div> <div> <p>【药品名称】</p> <p>通用名称：碘海醇注射液</p> <p>商品名称：枢刻明</p> <p>英文名称：Iohexol Injection</p> <p>汉语拼音：Dianhaichun Zhusheye</p> <p>【成 份】</p> <p>化学名称：本品主要成份为碘海醇， 其化学名为5－[N－(2,3－二羟丙基)乙酰胺基]－N，N'－双(2,3－二羟丙基)－2，4，6－三碘-1,3-苯二甲酰胺。</p> <p>分子式：C19H26I3N3O9</p> <p>分子量：821.14</p> <p>本品所用辅料为：依地酸钙钠、氨基丁三醇、盐酸。</p> <p>【性 状】</p> <p>本品为无色至淡黄色的澄明溶液。</p> <p>【适 应 症】</p> <p>X线造影剂。可用于心血管造影、动脉造影、尿路造影、静脉造影、CT增强检查；颈、胸和腰段椎管造影、经椎管蛛网膜下腔注射后CT脑池造影；关节造影、经内窥镜胰胆管造影（ERCP）、疝或瘘道造影、子宫输卵管造影、涎腺造影、经皮肝胆管造影（PTC）、窦道造影、胃肠道造影和“T”型管造影等。</p> <p>【规 格】</p> <p>（1）每50ml含碘海醇37.75g（以碘计浓度为350mg I/ml）；（2）每50ml含碘海醇25.9g（以碘计浓度为240mg I/ml）；（3）每75ml含碘海醇48.5g（以碘计浓度为300mg I/ml）；（4）每100ml含碘海醇75.5g（以碘计浓度为350mg I/ml）；（5）每100ml含碘海醇64.7g（以碘计浓度为300mg I/ml）；（6）每100ml含碘海醇51.77g（以碘计浓度为240mg I/ml）。</p> <p>【用法用量】</p> <p>给药剂量取决于检查的种类、病人的年龄、体重、心输出量和全身情况及使用的技术。一般而言，该药的常用碘浓度和容量与目前使用的其它含碘造影剂相似。和其它造影剂一样，在用药前后都必须保证体内有充足的水分。以下的剂量可作为临床指导。</p> <p>【不良反应】</p> <p>1、常见的不良反应为轻度的感觉异常，如热感或暂时性的金属味觉。腹部不适或疼痛很罕见（发病率<1﹕1000），胃肠道反应如恶心、呕吐也很少见（发病率<1﹕100，但>1﹕1000）。过敏样反应较少见，通常表现为轻度的呼吸道和皮肤反应，如呼吸困难、皮疹、红斑、荨麻疹、瘙痒和血管性水肿，它们可在注射后立即出现也可在几天后出现。严重的反应如喉头水肿、支气管痉挛或肺水肿非常少见。过敏样反应可能与剂量和用药途径无关。严重反应的最初症状可能仅是轻微的过敏症状，必须马上停止继续使用造影剂，必要时应立即通过血管给药进行相应的治疗。使用β受体阻滞剂的病人其过敏反应的症状可能不典型，容易误为迷走神经反应。迷走神经反应可引起低血压和心律过缓，很少见。严重皮肤反应如多行性渗出性红斑或中**表皮坏死溶解症很少见。偶可发热伴寒战。碘中毒或“碘中**腮腺炎”是一种罕见的与使用碘造影剂有关的并发症，表现为腮腺的肿胀和触痛，可在检查后持续达10天。</p> <p>2、和含碘造影剂有关的不良反应本质上一般都为轻到中度且为暂时性的，非离子型造影剂的不良反应要比离子型造影剂更少。重度反应和致死反应非常罕见。</p> <p>3、在动脉内注射造影剂所引起的不良反应性质与注射的部位和剂量有关。</p> <p>选择性动脉造影或其它相应的技术操作可使目标器官处于高浓度造影剂状态，可能会引起相应器官的并发症。外周血管造影常会引起远端的热感和疼痛（发病率>1﹕10）。短暂性S-肌酐上升也很常见，但通常无临床意义。肾功能衰竭非常罕见。不过有致死病例的报道。冠状、脑或肾动脉注射后会引起动脉痉挛并导致局部出血。神经系统反应非常罕见，它们可为癫痫发作或短暂</p> <p>性运动或感觉障碍。偶可在随访的CT扫描时见到造影剂通过血脑屏障为脑皮质摄取，有时可伴短暂性意识模糊或皮层盲。严重的心脏并发症如心律紊乱、心功能减退或心肌缺血都很少见。</p> <p>4、静脉造影后的血栓性静脉炎和静脉内血栓形成很少见。曾有极个别关节痛的病例报道。</p> <p>5、鞘内注射后的不良反应可能在检查后几小时甚至几天后延迟出现。其发生率与单独腰穿相似。头痛、恶心、呕吐和头晕很常见，主要与穿刺点脑脊液渗漏引起蛛网膜下腔压力下降有关。有些病人会有严重的头痛并持续几天。不要抽出太多的脑脊液以避免压力过度下降。轻度的局部疼痛、外周感觉异常和根性疼痛偶可发生在注射的部位（发病率<1﹕10，但>1﹕100）。下肢疼痛和痛性痉挛偶有见到。脑膜刺激所致的畏光和假性脑膜炎偶有发生。症状明显的化学性脑膜炎非常罕见，也应考虑有感染性脑膜炎的可能。非常少见的反应有短暂性脑功能失调，包括癫痫发作、短暂性意识丧失、运动和感觉障碍。少数病人有EEG的改变。</p> <p>6、体腔内使用时，全身性过敏反应少见。</p> <p>ERCP：淀粉酶水平略有升高比较常见。ERCP检查后偶可在肾脏内见到造影剂，此情况提示ERCP后胰腺炎的危险性大为增加。也有发生坏死性胰腺炎的个案报道。</p> <p>口服造影剂后偶可发生胃肠道不适。</p> <p>子宫输卵管造影：常有下腹部短暂性轻度疼痛。</p> <p>关节腔造影：造影术后疼痛比较常见。症状明显的关节炎罕见，此种病人应考虑感染性关节炎的可能。</p> <p>疝造影：轻度的术后疼痛较常见。</p> <p>【禁忌】</p> <p>有严重的甲状腺毒症表现的患者禁用；对本品过敏者禁用。</p> <p>【注意事项】</p> <p>1、有过敏、哮喘和对含碘制剂有过不良反应的需特别注意。对这些病例可考虑使用预防用药。如类固醇、H1，H2组胺受体阻滞剂等。</p> <p>2、碘造影剂可激发过敏样反应或其它过敏反应的表现。因此应预先进行急救措施的训练和预备必须的抢救药物和器械以应付可能出现的严重反应。</p> <p>3、鉴于预试验对由非离子型造影剂的过敏反应预测的准确性极低，以及预试验本身也可能导致严重过敏反应，因此不建议采用预试验来预测碘过敏反应。</p> <p>4、在整个X线检查过程中应始终保持静脉输液通路畅通。</p> <p>5、体外试验中，非离子型造影剂对凝血系统的影响较离子型造影剂为轻。在施行血管造影术时，应十分小心在血管内的技术操作，不时地用肝素化的生理盐水灌洗导管以减少与操作技术相关的血栓形成和栓塞。</p> <p>6、在用造影剂前后必须保证体内有足够的水分。这一点尤其适合患有多发性骨髓瘤、糖尿病、肾功能不全的病人及婴幼儿和老年人。小于1岁的婴儿，特别是新生儿易引起电解质紊乱和血液动力学失调。对有严重心脏病和肺动脉高压的病人需特别注意。因为他们易发展为血液动力学失调和心律紊乱。</p> <p>7、急性脑病、脑瘤或有癫痫病史的病人要预防癫痫发作并需特别的注意。酗酒和吸毒者其癫痫发作和神经系统反应危险性大为增加。少数病人在椎管造影后发生短暂性听力丧失或耳聋，这可能是腰穿后脑脊液压力下降所致。</p> <p>8、为预防使用造影剂后的急性肾功能衰竭，对已有肾功能损害和糖尿病的病人需要特别的注意，因为他们的危险性较大。异型球蛋白血症（多发性骨髓瘤病和Waldenstrom巨球蛋白血症）的病人危险性也较大。预防措施包括：</p> <p>—证实有高危险因素的病人。</p> <p>—确保体内有足够的水分。如有必要，可在检查前由静脉维持输液直到造影剂从肾脏清除。</p> <p>—在造影剂清除之前避免任何加重肾脏负担的肾毒**物、口服胆囊造影剂、动脉钳闭术、肾动脉成形术或其它大型手术。</p> <p>—延迟重复的造影检查直到肾功能恢复到检查前水平。</p> <p>严重肾功能不全的病人需特别注意，因为这些病人清除造影剂的时间明显延长。血透的病人在接受造影剂检查后应立即进行血液透析。</p> <p>含碘造影剂可加重重症肌无力的症状。嗜铬细胞瘤病人在介入治疗时应给予预防高血压危象的α受体阻滞剂。甲亢病人也需特别注意。多发结节性甲状腺肿的病人在使用碘造影剂后有发展成甲亢的可能。应清楚地认识到早产儿在使用造影剂后有短暂性甲减的可能。</p> <p>造影剂外渗时偶然会引起局部的疼痛和水肿，它们会逐渐消退，不留后遗症。不过，偶可见发生炎症甚至组织坏死的病例。常规处理方法为抬高患肢和局部冷敷。万一发生隔室综合症需手术减压。</p> <p>9、观察时间：</p> <p>使用造影剂后的病人应至少观察30分钟以上，因为大多数的严重不良反应都发生在这段时间。不过，仍有发生延迟反应的可能。</p> <p>10、鞘内注射：</p> <p>在椎管造影后，病人应休息1小时，头、胸抬高20°然后可小心下床行走但不要弯腰。如仍躺在床上，应保持头胸抬高6小时。对癫痫发作阈较低的病人在此期间应密切观察。门诊病人最初的24小时内不能独处。</p> <p>11、对驾驶和操作机器能力的影响：</p> <p>在鞘内注射后24小时内不应驾驶和操作机器。</p> <p>12、本品应象所有的非胃肠道药品一样在使用前目检，以检查是否有微粒、变色和与容器的粘连现象。</p> <p>药品应在使用前才被抽入针筒，每瓶仅供单次使用，丢弃未用部分。</p> <p>【孕妇及哺乳期妇女用药】</p> <p>人类妊娠期间使用本品的安全性并未确立。实验性动物研究的结果并不直接或间接表明在人类生殖、胚胎或胎儿发育中的损害作用。因为在妊娠的任何时候都应避免射线的照射，所以在考虑对妊娠妇女使用造影检查时必须慎重权衡利弊。碘海醇注射液不应用于妊娠妇女，除非临床医生认为利远大于弊时。</p> <p>造影剂在人类的乳汁中排出极少，再者通过胃肠道吸收的量也极少。因此对吃奶的婴儿损害的可能性很小。</p> <p>【儿童用药】尚未进行该项实验且无可靠参考文献。</p> <p>【老年用药】尚未进行该项实验且无可靠参考文献。</p> <p>【药物相互作用】</p> <p>1.使用造影剂可能会导致短暂性肾功能不全，这可使服用双胍类降糖药（****）的糖尿病人发生乳酸性酸中毒。作为预防，在使用造影剂前48小时应停服双胍类降糖药，只有在肾功能稳定后再恢复用药。</p> <p>2.二周内用白介素－2治疗的病人其延迟反应的危险性会增加（感冒样症状和皮肤反应）。</p> <p>3.所有的碘造影剂都会影响甲状腺功能的测定，甲状腺碘结合能力下降会持续几周。</p> <p>4.血清和尿中高浓度的造影剂会影响胆红素、蛋白或无机物（如铁、铜、钙和磷）的实验室测定结果。在使用造影剂的当天不应做这些检查。</p> <p>5.虽然没有明确的配伍禁忌，碘海醇仍不应与其他药物直接混合使用。应使用单独的注射器。</p> <p>【药物过量】</p> <p>临床前的实验数据提示本品有高度的安全范围，在日常血管内使用时还未制定出固定的剂量上限水平。全身性过量使用的可能性很小，除非病人接受高达2000mgI/公斤体重的剂量且超过限定时间。检查的持续时间很重要，因为肾脏耐受高浓度造影剂的能力有限（t1/2～2小时）。偶然的过量使用最可能发生在对儿童施行复杂的血管检查，特别是多次反复注射高浓度的造影剂。</p> <p>万一过量，必须马上纠正任何水电解质的不平衡。连续监测肾功能3天，如需要可进行血透以消除过量的造影剂。没有特殊的造影剂拮抗剂。</p> <p>【药理毒理】</p> <p>动物试验结果表明本品对犬肝脏、腹主动脉、CT扫描影像有增强效应。另据文献报道，本品的**较非离子型造影剂如甲泛葡胺的低；静注造影时，大鼠、兔子及犬主要从尿中排出，小部分（大鼠5%、犬1%）从粪便中排出。尚未发现任何器官吸收的现象，也未在动物中检测到任何代谢产物。本品蛋白结合率少于2%；犬肾动脉造影时有蛋白尿发生的现象。</p> <p>【药代动力学】</p> <p>据报道，通过静脉注射到体内的碘海醇，于24小时内以原状在尿液中排出的近乎百分之百，尿液中碘海醇浓度的情况，出现在注射后的一小时内，没有代谢产物产生。</p> <p>【贮 藏】遮光、密闭保存。</p> <p>【包 装】50ml、100ml玻璃输液瓶</p> <p>【有 效 期】36个月</p> <p>【执行标准】《中国药典》2015年版二部和YBH06492008</p> <p>【批准文号】</p> <p>（1）每50ml含碘海醇32.35g（以碘计浓度为300mg I/ml）国药准字H10980321</p> <p>（2）每50ml含碘海醇37.75g（以碘计浓度为350mg I/ml） 国药准字H20083565</p> <p>（3）每50ml含碘海醇25.9g（以碘计浓度为240mg I/ml） 国药准字H20083566</p> <p>（4）每75ml含碘海醇48.5g（以碘计浓度为300mg I/ml） 国药准字H20083567</p> <p>（5）每100ml含碘海醇75.5g（以碘计浓度为350mg I/ml） 国药准字H20083568</p> <p>（6）每100ml含碘海醇64.7g（以碘计浓度为300mg I/ml） 国药准字H20083569</p> <p>（7）每100ml含碘海醇51.77g（以碘计浓度为240mg I/ml） 国药准字H20083570</p> <p>【生产企业】福安药业集团宁波天衡制药有限公司</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="product-right"> <div class="company-card"> <div class="company-title">福安药业（集团）股份有限公司</div> <div class="company-link"> <div class="company-year"> <div>4</div> <div>Years</div> </div> <a href="/s-gakingday/" class="company-go"> <div>访问商铺</div> <div><i class="iconfont icon-xiangyoujiantou"></i></div> </a> </div> <div class="product-info"><span>注册资本</span>不愿意公开</div> <div class="product-info"><span>公司地址</span> <div class="limit-2">宁波市镇海区安平路366号</div> </div> <div class="product-info"><span>联系人</span><label id="person_name">王林峰</label></div> <div class="product-info"><span>联系电话</span><label id="linephone">86-574-86690023</label></div> <div class="product-info"><span>联系手机</span><label id="tel">13396691011</label></div> <div class="company-btn-line"> <input type="hidden" id="hiddenHideContactor" value="0"> <div 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