Express Genes | Twist Bioscience

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class="main-content col" id="content" role="main"> <section class="section"> <a id="main-content" tabindex="-1"></a> <div data-drupal-messages-fallback class="hidden"></div> <div id="block-twist-barrio-content" class="block block-system block-system-main-block"> <div class="content"> <article data-history-node-id="31356" about="/products/genes/express-genes" class="node node--type-drag-and-drop-page node--promoted node--view-mode-full clearfix"> <header> </header> <div class="node__content clearfix"> <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><div class="az-element az-container dxpr" data-az-type="node|drag_and_drop_page" data-az-name="31356|139776|field_body" data-az-human-readable="ZmllbGRfYm9keSBvbiBwYWdlIEV4cHJlc3MgR2VuZXMg" data-az-langcode="en" data-az-mode="dynamic"> <div class="az-element az-section hero video-bg container-fluid-wrapper az-color-style mb_YTPlayer isMuted" data-az-id="gb7m2nploi" data-azat-an_infinite="no" data-azat-effect="youtube" data-azat-parallax_mobile_disable="no" data-azat-parallax_mode="fixed" data-azat-parallax_speed="0" data-azat-pid="express-genes-video-bg" data-azat-video_options="disMobile,loop" data-azat-video_youtube="https://youtu.be/z0vNh-r5LXM" data-azb="az_section" data-property='{ videoURL: "z0vNh-r5LXM", containment: "[data-az-id=gb7m2nploi]", showControls: false, autoPlay: true, stopMovieOnBlur: false, loop: true, mute: true, optimizeDisplay: true, startAt: 0, stopAt: 0, useOnMobile: false, showYTLogo: false, isStandAlonePlayer: false, }' id="express-genes-video-bg" style="color: rgb(255, 255, 255); background-color: rgb(0, 0, 0); position: relative; padding-bottom: 56.25%; overflow: hidden; height: 0px;"> <div class="az-ctnr container-fluid" data-azcnt="true"> <div class="az-element az-row row az-row--md thin hover-style-gb6zvwhlk6" id="gbt2za0v6q" style="font-size:NaN;border-radius:NaN;opacity:NaN;"> <div class="az-element az-ctnr az-column text-center col-md-12" id="gbbzh3j8h1"> <div class="az-element az-text" id="gbz1zu1rbw"> <h1>Bastante rápido, pero no tanto como Express Genes.</h1> </div> <div class="az-element az-button az-button-content mx-auto" id="gb9ec11w4o"><a class="az-button-content btn btn-light" href="https://ecommerce.twistdna.com/app?ajs_uid=137226&ajs_aid=8279b150-01e8-4540-93ce-dfcbdb775979" role="button" style="border-radius:2px;" target="_blank">solicitar express genes </a></div> </div> </div> </div> <div class="inlinePlayButton" style="position: relative; display: none;">P</div> </div> <div class="inline-YTPlayer" style="position: relative; max-width: 1905px;"> </div> <div class="az-element az-section body-text-cta-centered mt-0 mb-0 p-5 az-color-style" data-az-id="gbnnu7rqzc" data-azat-an_infinite="no" data-azat-parallax_mobile_disable="no" data-azat-parallax_mode="fixed" data-azat-parallax_speed="0" data-azat-pid="gbzpj8nbi3" data-azb="az_section" id="gbzpj8nbi3" style="color:#ffffff;background-color:#232e35;"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md col-ten" id="gbtf1u0ljy"> <div class="az-element az-ctnr az-column col-md-12" id="gbz407st40"> <div class="az-element az-text" id="gb66mfwsue"> <h2 style="text-align: center; color: #2AD39B;">Presentación de Express Genes de Twist</h2> <p style="text-align: center;"><strong>Clonal Genes made in the US to your specifications and shipped to you in as few as 4 days.*</strong></p> <p style="text-align: center;"><br> Seguimiento rápido de su investigación con Express Genes de Twist. Este nuevo servicio le proporciona genes clonados de secuencia perfecta y verificados mediante secuenciación de última generación (NGS), sintetizados con una longitud de entre 0,3 y 5 kb, y clonados en el vector de su selección, todo en entre 4 y 7 días laborables.* Con un tiempo de producción rápido y una calidad como estos, puede esperar velocidad y precisión para todas las aplicaciones, lo que incluye la ingeniería de anticuerpos, la investigación para el descubrimiento de fármacos, la síntesis de ARN mensajero y mucho más.</p> </div> </div> </div> </div> </div> <div class="az-element az-section list-icons-square m-0" data-az-id="gbe907htgm" data-azat-an_infinite="no" data-azat-parallax_mobile_disable="no" data-azat-parallax_mode="fixed" data-azat-parallax_speed="0" data-azat-pid="gbv4vjl0gv" data-azb="az_section" id="gbv4vjl0gv"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md text-center col-ten mt-4" id="gbxdy09zc0"> <div class="az-element az-ctnr az-column col-md-12" id="gbadtiqfmj"> <div class="az-element az-text" id="gbzmga5q58"> <h2>¿Por qué elegir Express Genes?</h2> </div> </div> </div> <div class="az-element az-row row az-row--md row-items justify-content-between col-ten" id="gbe5rfzzrs"> <div class="az-element az-ctnr az-column text-center col-md-6" id="gbtixcyfxv"> <div class="az-element az-text" id="gbcaqn5iry"><a class="d-block link-box" href="/es/products/genes?tab=clonal&&"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/inline-images/Vectoricons1.png" style="width: 64px;" title=""></a> <h5 style="text-align: center;"><a class="d-block link-box" href="/es/products/genes?tab=clonal&&">Entrega ultrarrápida</a></h5> <p><a class="d-block link-box" href="/es/products/genes?tab=clonal&&">Disfrute de una síntesis de genes acelerada con un tiempo de entrega de 4-7 días laborables.*</a></p> </div> </div> <div class="az-element az-ctnr az-column col-md-6" id="gbb6ahcjmn"> <div class="az-element az-text" id="gbot8n1heh"><a class="link-box" href="/es/products/genes?tab=clonal#clonal_data"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/inline-images/Group%20607icons2.png" style="width: 64px;" title=""></a> <h5 style="text-align: center;"><a class="link-box" href="/es/products/genes?tab=clonal#clonal_data">Genes clonados de secuencia perfecta</a></h5> <p><a class="link-box" href="/es/products/genes?tab=clonal#clonal_data">Las secuencias de Express Genes se verifican mediante secuenciación de última generación (NGS), lo que garantiza una mayor precisión y fiabilidad para los experimentos.</a></p> </div> </div> </div> </div> </div> <div class="az-element az-section list-icons-square mt-0" data-az-id="gbhjeyd3sv" data-azat-an_infinite="no" data-azat-parallax_mobile_disable="no" data-azat-parallax_mode="fixed" data-azat-parallax_speed="0" data-azat-pid="gbbtq23w1s" data-azb="az_section" id="gbbtq23w1s"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md row-items justify-content-between" id="gbwggpln5j"> <div class="az-element az-ctnr az-column text-center col-md-4" id="gbxka4z8q6"> <div class="az-element az-text" id="gbsqebjhfm"><a class="d-block link-box" href="/es/products/genes?tab=clonal&&"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/inline-images/Group%20405icons3.png" style="width: 64px;" title=""></a> <h5 style="text-align: center;"><a class="d-block link-box" href="/es/products/genes?tab=clonal&&">Personalización al alcance de su mano </a></h5> <p><a class="d-block link-box" href="/es/products/genes?tab=clonal&&">Elija cualquier vector y especifique la longitud genética que desee entre 0,3 y 0,5 kb.</a></p> </div> </div> <div class="az-element az-ctnr az-column col-md-4" id="gb62gc9lsf"> <div class="az-element az-text" id="gb58y6rqj6"><a class="d-block link-box" href="/es/contact?&"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/inline-images/Group%20592icon4.png" style="width: 64px;" title=""></a> <h5 style="text-align: center;"><a class="d-block link-box" href="/es/contact?&">Atención al cliente especializada</a></h5> <p><a class="d-block link-box" href="/es/contact?&">Dispone de un equipo para asistirle con el pedido y los detalles técnicos cuando lo necesite. </a></p> </div> </div> <div class="az-element az-ctnr az-column col-md-4" id="gb3kwslbpn"> <div class="az-element az-text" id="gbplar47bm"><a class="d-block link-box" href="/es/legal/satisfaction-policy?&"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/inline-images/Group%20607icons5.png" style="width: 64px;" title=""></a> <h5 style="text-align: center;"><a class="d-block link-box" href="/es/legal/satisfaction-policy?&">Política de satisfacción de Twist</a></h5> <p><a class="d-block link-box" href="/es/legal/satisfaction-policy?&">Nos comprometemos a enviarle sus genes clonados de secuencia perfecta en 4-7 días laborables.*</a></p> </div> </div> </div> </div> </div> <div class="az-element az-section" data-az-id="gbkn732jjr" data-azat-pid="gbaovoqzaf" data-azb="az_section" id="gbaovoqzaf"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md" id="gb0gyqgjmw"> <div class="az-element az-ctnr az-column text-center col-md-12" id="gbvnhzd8o2"> <div class="az-element az-button az-button-content mx-auto" id="gbpd1xnxpv"><a class="az-button-content btn btn-outline-dark" href="https://ecommerce.twistdna.com/app?ajs_uid=137226&ajs_aid=8279b150-01e8-4540-93ce-dfcbdb775979" role="button" target="_blank">Empezar</a></div> </div> </div> </div> </div> <div class="az-element az-section list-icons-square pb-5 az-color-style" data-az-id="gbkuhv0asw" data-azat-an_infinite="no" data-azat-parallax_mobile_disable="no" data-azat-parallax_mode="fixed" data-azat-parallax_speed="0" data-azat-pid="gb1i73uw7i" data-azb="az_section" id="gb1i73uw7i" style="color:#ffffff;background-color:#354652;"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md text-center col-ten" id="gby4u81wmy"> <div class="az-element az-ctnr az-column col-md-12" id="gbyv4znjno"> <div class="az-element az-text" id="gbbb3rcc4t"> <h2>¡Tan sencillo como 1-2-3!</h2> </div> </div> </div> <div class="az-element az-row row az-row--md row-items caveman justify-content-between align-items-start" id="gblcpvan2w"> <div class="az-element az-ctnr az-column text-center col-md-4" id="gb9fjwpy0v"> <div class="az-element az-image" id="gbi2rpvkcd"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/dxpr_builder_images/Group%20608.png?fid=34576" style="" title=""></div> <div class="az-element az-text" id="gbhg7s7q5k"> <h5 style="text-align: center;">Inicio del diseño de sus genes</h5> <p><u><a href="https://id.twistdna.com/?&" target="_blank">Cargue</a></u> sus secuencias de genes.</p> </div> </div> <div class="az-element az-ctnr az-column col-md-4" id="gb20imm7iz"> <div class="az-element az-image" id="gbkogjmg4p"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/dxpr_builder_images/Group%20609.png?fid=34581" style="" title=""></div> <div class="az-element az-text" id="gbwguoeefr"> <h5 style="text-align: center;">Selección de los Express Genes</h5> <p>Cargue las secuencias, seleccione las personalizaciones de los Express Genes y envíe el pedido.</p> </div> </div> <div class="az-element az-ctnr az-column col-md-4" id="gbthh804wp"> <div class="az-element az-image" id="gbqjzlj1m1"><img class="az-image-content" src="https://www.twistbioscience.com/sites/default/files/dxpr_builder_images/Group%20610.png?fid=34586" style="" title=""></div> <div class="az-element az-text" id="gbaxspdi3n"> <h5 style="text-align: center;">Siéntese y relájese</h5> <p>Your perfect NGS-verified Clonal Genes will be manufactured in the US and shipped in as few as 4 days.*</p> </div> </div> </div> </div> </div> <div class="az-element az-section mt-0 pt-4 az-color-style" data-az-id="gbqktfbm91" data-azat-pid="gbs3zzekz8" data-azb="az_section" id="gbs3zzekz8" style="color:#ffffff;background-color:#1e986f;"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-ctnr az-column col-undefined-12" id="gb7gj6yl7b"> <div class="az-element az-text" id="gb4wemuq70"> </div> </div> <div class="az-element az-text col-eight" id="gbl31ukkxo"> <h2 style="text-align: center;">¿Tiene problemas con sus secuencias de genes?</h2> <p style="text-align: center;"><span style="font-size:22px;"><strong>Utilice nuestra nueva herramienta de optimización del codón para crear secuencias aptas para Express Genes.</strong></span></p> </div> <div class="az-element az-button az-button-content text-center d-block mt-4 mb-4" id="gbxhob2vuo"><a class="az-button-content btn btn-light" href="/es/resources/digital-tools/codon-optimization-tool" role="button" target="_blank">Optimizar ahora </a></div> </div> </div> <div class="az-element az-section body-text-cta-bottom az-color-style" data-az-id="gbpy5lr54u" data-azat-pid="gb7f7qddcz" data-azb="az_section" id="gb7f7qddcz" style="color:#232e35;background-color:#ffffff;"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md col-eight" id="gbwmlsrxzx"> <div class="az-element az-ctnr az-column col-md-12" id="gbhwyya6wr"> <div class="az-element az-text" id="gbelbzok9h"> <h2 style="text-align: center;">¿Listo para acelerar y transformar su investigación con Express Genes?</h2> </div> </div> </div> <div class="az-element az-row row az-row--md ten-col hover-style-gbqj4ri6c1" id="gbm9pa1gpd" style="font-size:NaN;border-radius:NaN;opacity:NaN;"> <div class="az-element az-ctnr az-column d-flex justify-content-center col-md-12" id="button-float-wrap"> <div class="az-element az-button az-button-content m-3" id="gbxou43fp2"><a class="az-button-content btn btn-outline-dark" href="/es/contact" role="button" target="_blank">Póngase en contacto con nuestro equipo. </a></div> <div class="az-element az-button az-button-content m-3" id="gb0mfrnw5w"><a class="az-button-content btn btn-dark" href="https://ecommerce.twistdna.com/app?ajs_uid=137226&ajs_aid=8279b150-01e8-4540-93ce-dfcbdb775979" role="button" target="_blank">iniciar pedido </a></div> </div> </div> </div> </div> <div class="az-element az-section mt-0 mb-0 pt-5" data-az-id="gbb0ll853c" data-azat-pid="gb60097bnf" data-azb="az_section" id="gb60097bnf" style="padding-bottom:80px;background-color:#fafbfd;"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-text col-eight" id="gban7jzmoc"> <h2>Preguntas frecuentes</h2> </div> <div class="az-element az-accordion panel-group accordion col-eight" data-az-id="gbfgot3a0g" data-azat-an_infinite="no" data-azat-collapsed="yes" data-azat-pid="gbj7qqzexn" data-azb="az_accordion" data-azcnt="true" id="gbj7qqzexn"> <div class="az-element az-toggle accordion-item" id="gb1wqhhw51"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb1wqhhw51-collapse" data-bs-toggle="collapse" role="button">¿Qué son los Express Genes? ¿Son lo mismo que los Clonal Genes con el servicio Exprés?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb1wqhhw51-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbt6pcnhct"> <p>Los Express Genes son Clonal Genes producidos más rápido con el servicio Exprés de Twist. El servicio Exprés reduce el tiempo de producción habitual de 10 a 15 días laborables a de 5 a 7 días laborables sin comprometer la calidad en ninguna etapa.*</p> <p>Ampliación de ADN de 50 ng-2 µg y 2 µg-10 µg:</p> <p>Estándar: 10-15 días laborables</p> <p>Express: De 4 a 7 días laborables</p> <p>Ampliación de ADN de 10 µg-100 µg y 100 µg-1 mg:</p> <p>Estándar: 13 a 20 días laborables</p> <p>Express: 8 a 10 días laborables</p> <p class="light-small">* Términos y condiciones: El tiempo de entrega publicitado para Express Clonal Genes es de 4 a 7 días laborables y se basa en una amplia experiencia de producción. El tiempo de producción puede variar de secuencia a secuencia. Se puede requerir un tiempo de envío adicional para los pedidos internacionales. El coste de los Express Genes depende de la capacidad del chip en el momento del envío del pedido y varía.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbwzsep9s5"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbwzsep9s5-collapse" data-bs-toggle="collapse" role="button">¿Cómo fabrica Twist Bioscience los Express Genes tan rápidamente?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbwzsep9s5-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbfn6zeplf"> <p>Pedir Clonal Genes con nuestro servicio Exprés le garantiza que un pedido reciba la máxima prioridad en cada etapa de producción. Gracias a los recursos adicionales dedicados a nuestro nuevo nivel de servicio, este enfoque prioritario nos permite acelerar la producción de Clonal Genes sin comprometer la calidad.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbbxi5cw6k"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbbxi5cw6k-collapse" data-bs-toggle="collapse" role="button">¿Incluyen los tiempos de entrega de Express Gene el tiempo de envío?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbbxi5cw6k-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbei0onv3d"> <p>No, el tiempo de entrega de 4 a 7 días laborables es el tiempo que se tarda para fabricar los Express Genes.* </p> <p>Todos Clonal Genes (Exprés y Estándar) se envían con el servicio nocturno y prioritario.</p> <p>Los tiempos de envío típicos por región son como se presenta a continuación: </p> <ul> <li>América del Norte: 1 a 2 días laborables</li> <li>Europa: 2 a 3 días laborables</li> <li>Asia: 2-4 días laborables</li> <li>Sudamérica: 3 a 6 días laborables</li> </ul> <p>Los Express Genes solicitados con reservas de glicerol y Express Genes con las ampliaciones de ADN de 10 μg-100 μg y 100 μg-1 mg (es decir, ADN resuspendido) se envían en hielo seco, lo que puede añadir un día laborable al tiempo de entrega total.</p> <p>Entre las consideraciones generales que pueden retrasar el envío y la entrega, se incluyen las siguientes:</p> <ul> <li>Problemas con los métodos de pago</li> <li>Requisitos de importación específicos de cada país</li> <li>Control de la secuencia de bioseguridad</li> </ul> <p class="light-small">* Términos y condiciones: El tiempo de entrega publicitado para Express Clonal Genes es de 4 a 7 días laborables y se basa en una amplia experiencia de producción. El tiempo de producción puede variar de secuencia a secuencia. Se puede requerir un tiempo de envío adicional para los pedidos internacionales. El coste de los Express Genes depende de la capacidad del chip en el momento del envío del pedido y varía.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gb8jxve3at"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb8jxve3at-collapse" data-bs-toggle="collapse" role="button">¿Incluye el tiempo de entrega del servicio de Express Genes el nuevo vector personalizado a bordo?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb8jxve3at-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbxufu33qm"> <p>No, los nuevos vectores personalizados necesitarán estar a bordo antes del pedido de los Express Genes. Para que los nuevos vectores personalizados estén a bordo, se tardará aproximadamente de 2 a 3 semanas. Para obtener más información sobre los vectores personalizados a bordo, consulte el <a href="/es/faq/custom-vector-onboarding?&">enlace</a> de nuestras preguntas frecuentes.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbnlakoiq8"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbnlakoiq8-collapse" data-bs-toggle="collapse" role="button">¿Qué escala de ADN y qué opciones de formato están disponibles para los Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbnlakoiq8-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbsiulrwnx"> <p>Los Express Genes están disponibles en los tamaños de preparación de ADN siguientes: 50 ng-2 μg, 2 μg-10 μg, 10 μg-100 μg y 100 μg-1 mg. El tiempo de entrega aumenta con el tamaño de la preparación como sigue: 5-7 días laborables para 50 ng-2 μg y 2 μg-10 μg, y 8-12 días laborables para 10 μg-100 μg y 100 μg-1 mg. Las mismas opciones de formato de envío están disponibles para los genes estándar y Express Genes.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbpnt2sxy1"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbpnt2sxy1-collapse" data-bs-toggle="collapse" role="button">¿Puedo pedir todas mis secuencias como Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbpnt2sxy1-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gb2f38d7wx"> <p>Las secuencias de genes clonados calificadas como de complejidad “Estándar” son elegibles para el servicio Exprés. La <a href="https://ecommerce.twistdna.com/app?&ajs_uid=137226&ajs_aid=8279b150-01e8-4540-93ce-dfcbdb775979&">plataforma de comercio electrónico</a> de Twist Bioscience califica todas las secuencias una vez que se cargan y destaca las que son elegibles para el servicio Exprés.</p> <p>Consulte <a href="/es/faq/gene-synthesis/what-do-scoring-results-my-gene-mean?&">aquí</a> para obtener información adicional sobre los parámetros de calificación de secuencias. </p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbl0hx1b9y"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbl0hx1b9y-collapse" data-bs-toggle="collapse" role="button">¿Cuáles son los criterios de aceptación de la secuencia para los Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbl0hx1b9y-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbd323i8gn"> <p>Todas las secuencias de Clonal Genes entre 300 bp y 5000 bp que nuestro examinador califique como de complejidad “Estándar” son elegibles para el servicio Exprés.</p> <p>Nuestro sistema de puntuación adopta un modelo de aprendizaje automático que analiza y combina múltiples parámetros de secuencia (es decir, porcentaje global de GC, longitud máxima de homopolímero, longitud máxima de repetición, longitud de secuencia, densidad de repetición, etc.). Este modelo se ha entrenado utilizando nuestros datos históricos de fabricación y proporciona una estimación más precisa del resultado satisfactorio de la producción de genes y anticuerpos.</p> <p>Los problemas de complejidad se deben principalmente a estructuras repetitivas y contenido de GC en el extremo. Las pautas para el diseño de secuencias se encuentran disponibles <a href="https://ecommerce.twistdna.com/app/design-guidelines?&ajs_uid=137226&ajs_aid=8279b150-01e8-4540-93ce-dfcbdb775979&">en línea</a> y a continuación:</p> <ul> <li>Evitar repeticiones de ≥20 bp o Tm ≥60 C </li> <li>El contenido de GC global debe ser entre 25 % y 65 %</li> <li>Evite las diferencias extremas en el contenido de GC dentro de un gen (es decir, la diferencia en el contenido de GC entre el tramo de 50 pb más alto y el más bajo no debe ser superior al 52 %)</li> <li>Minimizar los homopolímeros</li> <li>Minimizar el número/la longitud de pequeñas repeticiones dispersas a lo largo de la secuencia</li> <li>Para las etiquetas HIS, utilice una combinación de codones CAC y CAT, es decir, CACCAT</li> </ul> <p>la posibilidad de aceptación de la secuencia mejora al limitar las repeticiones y reducir el contenido de GC. Por ejemplo: Un gen puede recibir la calificación de “No aceptado” con un 66 % general de contenido de GC, pero cuando se reduce a un 65 % o menos, puede aceptarse como una secuencia “Compleja”. Seguir reduciendo el contenido de GC a ~60 % o menos puede mejorar la calificación de complejidad a “Estándar”, punto en el que la secuencia sería elegible para el servicio Exprés. Lo mismo ocurre con la eliminación de repeticiones, la reducción de los estiramientos de homopolímeros y la uniformidad de variaciones extremas en las ventanas de GC. Cuantas más estructuras de este tipo puedan evitarse o reducirse en un gen, más probabilidades tendrá de calificar para el servicio Exprés.</p> <p>Para obtener más información sobre nuestro algoritmo de calificación y nuestro diseño de secuencias, consulte nuestras <a href="/es/faq/gene-synthesis/what-do-scoring-results-my-gene-mean?&">preguntas frecuentes</a>.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbb6i1dzbr"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbb6i1dzbr-collapse" data-bs-toggle="collapse" role="button">¿Por qué no califican las secuencias complejas para el servicio Exprés?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbb6i1dzbr-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbfqn4ctej"> <p>Las secuencias complejas suelen requerir más tiempo de producción para su síntesis y clonación, y, por lo tanto, solo están disponibles a la velocidad de producción estándar.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gb0me735z0"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb0me735z0-collapse" data-bs-toggle="collapse" role="button">¿Cuáles son las diferencias entre las ofertas de Exprés y Estándar de Clonal Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb0me735z0-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gb4vioixvf"> <p>El servicio Exprés es un servicio mejorado de Clonal Genes que proporciona un tiempo de entrega más rápido que nuestro servicio Estándar. A continuación, encontrará un desglose detallado de las diferencias entre los servicios Estándar y Exprés:</p> <p><img src="https://www.twistbioscience.com/sites/default/files/inline-images/Screenshot%202024-01-23%20at%2010.47.36%20PM.png" style="width: 638px; height: 542px;"></p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbca7er6nq"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbca7er6nq-collapse" data-bs-toggle="collapse" role="button">¿Tiene el servicio Exprés un coste adicional?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbca7er6nq-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gb7jbggmgg">Sí, se agrega un coste a cada gen con el servicio Exprés aplicado. No se facturará el coste de ningún Express Gene que no se envíe en el plazo de entrega anunciado.</div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbbfqwudzw"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbbfqwudzw-collapse" data-bs-toggle="collapse" role="button">¿Por qué cambia el precio para los Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbbfqwudzw-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbciqd40lc">El servicio de Express Genes emplea precios dinámicos para garantizar la disponibilidad en todo momento y una entrega puntual fiable, especialmente en períodos de gran demanda. Cuando haya un cambio de precio, se reflejará en nuestra plataforma de comercio electrónico.</div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gb5kjxrx9h"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb5kjxrx9h-collapse" data-bs-toggle="collapse" role="button">¿Qué ocurre si no quiero pagar el coste adicional para los Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb5kjxrx9h-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbb9re2p5b"> <p>Seguimos ofreciendo Clonal Genes producidos con nuestra velocidad de servicio Estándar, que tiene un tiempo de entrega de 10 a 15 días laborables.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbm0tvi18o"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbm0tvi18o-collapse" data-bs-toggle="collapse" role="button">¿Cómo se aplicará el coste Exprés si tengo precio por contrato?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbm0tvi18o-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbbjram9t4"> <p>El precio contratado se reflejará en el precio base de cada gen, y el coste del servicio Exprés se añade como un elemento independiente relativo a ese precio base contratado.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gb5pj71qbu"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb5pj71qbu-collapse" data-bs-toggle="collapse" role="button">¿Qué ocurre si los Express Genes no se envían a tiempo o no estoy satisfecho con el pedido de Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb5pj71qbu-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbp74v0jum"> <p>Twist se compromete a proporcionar la mejor experiencia posible. En caso de que los Express Genes se entreguen tarde, se descontará el 100 % del coste del servicio Exprés y se le facturará el precio de Clonal Genes Estándar. <a href="/es/legal/terms-conditions?&">Aquí</a> están los Términos y condiciones para la política.</p> <p>Asimismo, respaldamos Express Genes con nuestra <a href="/es/legal/Satisfaction-Policy?&">Política de satisfacción de Twist</a>. En caso de que no esté satisfecho con Express Genes, notifíquenoslo durante los treinta (30) días posteriores a la realización del pedido.</p> </div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gb581tm7kv"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb581tm7kv-collapse" data-bs-toggle="collapse" role="button">¿Qué significa que el icono Exprés esté en gris en una secuencia?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb581tm7kv-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbory7ckuj">Solo las secuencias de complejidad “Estándar” son elegibles para el servicio Exprés. Si una secuencia genética aparece en gris en la sección de Express Genes, significa que es una secuencia “Compleja” o “No aceptada” y se marcará como tal en la plataforma de comercio electrónico.</div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gbtou354ox"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gbtou354ox-collapse" data-bs-toggle="collapse" role="button">¿Existe un pedido máximo para los Express Genes?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gbtou354ox-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gbh54ufk8z">Sí, el límite máximo al configurar un proyecto en la plataforma de comercio electrónico es de 1152 Express Genes. Si tiene previsto realizar un pedido con más de 1152 Express Genes, póngase en contacto con el servicio de atención al cliente para que le ayuden a hacer su pedido.</div> </div> </div> </div> <div class="az-element az-toggle accordion-item" id="gb5kaptocx"> <h2 class="accordion-header"><button aria-expanded="false" class="accordion-button collapsed" data-bs-target="#gb5kaptocx-collapse" data-bs-toggle="collapse" role="button">Recibí el siguiente mensaje cuando traté de hacer el pedido de los Express Genes, ¿qué significa esta alerta?</button></h2> <div class="collapse" data-bs-parent="#gbj7qqzexn" id="gb5kaptocx-collapse" role="tabpanel"> <div class="accordion-body az-ctnr" data-azcnt="true"> <div class="az-element az-text" id="gb86gvuqxf"> <p><img src="https://lh7-us.googleusercontent.com/R0qjlHtII0B0Md8iZTOn_cwQ_Scp9d2GY1oyE0ZVxcqNaUOOZV2NjEXinLkeUd4NdLDNMK6DwpH-qFtoEVGnZyASGRwNc1IsAf0hvyclSDea1_CKavTQFE156vPbFUPQt3Kh7bWGiWqwxqfzQ6X7Rcs" style="max-width: 100%;"></p> <p>Esto indica que hemos alcanzado la capacidad máxima para la producción actual de Express Genes. Los Express Genes se producen varias veces al día, vuelva a probar pronto.</p> </div> </div> </div> </div> </div> </div> </div> <div class="az-element az-section mt-0" data-az-id="gbr7dilm9h" data-azat-pid="gbveqqha3s" data-azb="az_section" id="gbveqqha3s"> <div class="az-ctnr container" data-azcnt="true"> <div class="az-element az-row row az-row--md col-eight" id="gb79sku6hl"> <div class="az-element az-ctnr az-column col-md-12" id="gbyn529dzg"> <div class="az-element az-text" id="gb2fzd6ngf"> <p style="font-size:8px;">* Términos y condiciones: Las personalizaciones de Express Genes incluyen la selección de los vectores del catálogo de Twist o la incorporación de su propio vector personalizado para la clonación de longitudes de secuencias que van desde los 0,3 hasta los 5,0 kb y las escalas de preparación de ADN de 50 ng-2 μg, 2 μg-10 μg, 10 μg-100 μg y 100 μg-1 mg. El tiempo de entrega para Express Genes va de 4-7 días laborables a 8-10 días laborables para las escalas de preparación de ADN de 10 μg-100 μg y 100 μg-1 mg. La incorporación de su propio vector personalizado conllevará un plazo adicional de 1 a 2 semanas.</p> <p style="font-size: 8px; text-align: center;">Solo para investigación. 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