CINXE.COM

<!DOCTYPE html> <html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-sticky-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-disabled skin-theme-clientpref-day vector-toc-available" lang="id" dir="ltr"> <head> <meta charset="UTF-8"> <title>Reseptor (biokimia) - Wikipedia bahasa Indonesia, ensiklopedia bebas</title> <script>(function(){var className="client-js vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-sticky-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-disabled skin-theme-clientpref-day vector-toc-available";var cookie=document.cookie.match(/(?:^|; )idwikimwclientpreferences=([^;]+)/);if(cookie){cookie[1].split('%2C').forEach(function(pref){className=className.replace(new RegExp('(^| )'+pref.replace(/-clientpref-\w+$|[^\w-]+/g,'')+'-clientpref-\\w+( |$)'),'$1'+pref+'$2');});}document.documentElement.className=className;}());RLCONF={"wgBreakFrames":false,"wgSeparatorTransformTable":[",\t.",".\t,"],"wgDigitTransformTable":["",""], "wgDefaultDateFormat":"dmy","wgMonthNames":["","Januari","Februari","Maret","April","Mei","Juni","Juli","Agustus","September","Oktober","November","Desember"],"wgRequestId":"1ab7a2fb-aba6-469d-9174-857b94fb12bd","wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"Reseptor_(biokimia)","wgTitle":"Reseptor (biokimia)","wgCurRevisionId":24976795,"wgRevisionId":24976795,"wgArticleId":944243,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":["Biologi membran","Biologi sel"],"wgPageViewLanguage":"id","wgPageContentLanguage":"id","wgPageContentModel":"wikitext","wgRelevantPageName":"Reseptor_(biokimia)","wgRelevantArticleId":944243,"wgIsProbablyEditable":true,"wgRelevantPageIsProbablyEditable":true,"wgRestrictionEdit":[],"wgRestrictionMove":[],"wgNoticeProject":"wikipedia","wgCiteReferencePreviewsActive":false,"wgFlaggedRevsParams":{"tags":{"accuracy":{"levels":2}}},"wgMediaViewerOnClick" :true,"wgMediaViewerEnabledByDefault":true,"wgPopupsFlags":0,"wgVisualEditor":{"pageLanguageCode":"id","pageLanguageDir":"ltr","pageVariantFallbacks":"id"},"wgMFDisplayWikibaseDescriptions":{"search":true,"watchlist":true,"tagline":true,"nearby":true},"wgWMESchemaEditAttemptStepOversample":false,"wgWMEPageLength":20000,"wgRelatedArticlesCompat":[],"wgCentralAuthMobileDomain":false,"wgEditSubmitButtonLabelPublish":true,"wgULSPosition":"interlanguage","wgULSisCompactLinksEnabled":false,"wgVector2022LanguageInHeader":true,"wgULSisLanguageSelectorEmpty":false,"wgWikibaseItemId":"Q208467","wgCheckUserClientHintsHeadersJsApi":["brands","architecture","bitness","fullVersionList","mobile","model","platform","platformVersion"],"GEHomepageSuggestedEditsEnableTopics":true,"wgGETopicsMatchModeEnabled":false,"wgGEStructuredTaskRejectionReasonTextInputEnabled":false,"wgGELevelingUpEnabledForUser":false};RLSTATE={"ext.gadget.charinsert-styles":"ready","ext.globalCssJs.user.styles":"ready", "site.styles":"ready","user.styles":"ready","ext.globalCssJs.user":"ready","user":"ready","user.options":"loading","ext.cite.styles":"ready","ext.math.styles":"ready","skins.vector.search.codex.styles":"ready","skins.vector.styles":"ready","skins.vector.icons":"ready","ext.wikimediamessages.styles":"ready","ext.visualEditor.desktopArticleTarget.noscript":"ready","ext.uls.interlanguage":"ready","wikibase.client.init":"ready","ext.wikimediaBadges":"ready"};RLPAGEMODULES=["ext.cite.ux-enhancements","mediawiki.page.media","site","mediawiki.page.ready","mediawiki.toc","skins.vector.js","ext.centralNotice.geoIP","ext.centralNotice.startUp","ext.gadget.ReferenceTooltips","ext.gadget.watchlist-notice","ext.gadget.charinsert","ext.gadget.refToolbar","ext.gadget.AdvancedSiteNotices","ext.gadget.switcher","ext.gadget.Bagikan","ext.gadget.CurIDLink","ext.urlShortener.toolbar","ext.centralauth.centralautologin","mmv.bootstrap","ext.popups","ext.visualEditor.desktopArticleTarget.init", "ext.visualEditor.targetLoader","ext.echo.centralauth","ext.eventLogging","ext.wikimediaEvents","ext.navigationTiming","ext.uls.interface","ext.cx.eventlogging.campaigns","ext.cx.uls.quick.actions","wikibase.client.vector-2022","ext.checkUser.clientHints","ext.growthExperiments.SuggestedEditSession","oojs-ui.styles.icons-media","oojs-ui-core.icons","wikibase.sidebar.tracking"];</script> <script>(RLQ=window.RLQ||[]).push(function(){mw.loader.impl(function(){return["user.options@12s5i",function($,jQuery,require,module){mw.user.tokens.set({"patrolToken":"+\\","watchToken":"+\\","csrfToken":"+\\"}); }];});});</script> <link rel="stylesheet" href="/w/load.php?lang=id&modules=ext.cite.styles%7Cext.math.styles%7Cext.uls.interlanguage%7Cext.visualEditor.desktopArticleTarget.noscript%7Cext.wikimediaBadges%7Cext.wikimediamessages.styles%7Cskins.vector.icons%2Cstyles%7Cskins.vector.search.codex.styles%7Cwikibase.client.init&only=styles&skin=vector-2022"> <script async="" src="/w/load.php?lang=id&modules=startup&only=scripts&raw=1&skin=vector-2022"></script> <meta name="ResourceLoaderDynamicStyles" content=""> <link rel="stylesheet" href="/w/load.php?lang=id&modules=ext.gadget.charinsert-styles&only=styles&skin=vector-2022"> <link rel="stylesheet" href="/w/load.php?lang=id&modules=site.styles&only=styles&skin=vector-2022"> <meta name="generator" content="MediaWiki 1.44.0-wmf.4"> <meta name="referrer" content="origin"> <meta name="referrer" content="origin-when-cross-origin"> <meta name="robots" content="max-image-preview:standard"> <meta name="format-detection" content="telephone=no"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Receptor_%28Biochemistry%29.svg/1200px-Receptor_%28Biochemistry%29.svg.png"> <meta property="og:image:width" content="1200"> <meta property="og:image:height" content="722"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Receptor_%28Biochemistry%29.svg/800px-Receptor_%28Biochemistry%29.svg.png"> <meta property="og:image:width" content="800"> <meta property="og:image:height" content="481"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Receptor_%28Biochemistry%29.svg/640px-Receptor_%28Biochemistry%29.svg.png"> <meta property="og:image:width" content="640"> <meta property="og:image:height" content="385"> <meta name="viewport" content="width=1120"> <meta property="og:title" content="Reseptor (biokimia) - Wikipedia bahasa Indonesia, ensiklopedia bebas"> <meta property="og:type" content="website"> <link rel="preconnect" href="//upload.wikimedia.org"> <link rel="alternate" media="only screen and (max-width: 640px)" href="//id.m.wikipedia.org/wiki/Reseptor_(biokimia)"> <link rel="alternate" type="application/x-wiki" title="Sunting" href="/w/index.php?title=Reseptor_(biokimia)&action=edit"> <link rel="apple-touch-icon" href="/static/apple-touch/wikipedia.png"> <link rel="icon" href="/static/favicon/wikipedia.ico"> <link rel="search" type="application/opensearchdescription+xml" href="/w/rest.php/v1/search" title="Wikipedia (id)"> <link rel="EditURI" type="application/rsd+xml" href="//id.wikipedia.org/w/api.php?action=rsd"> <link rel="canonical" href="https://id.wikipedia.org/wiki/Reseptor_(biokimia)"> <link rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/deed.id"> <link rel="alternate" type="application/atom+xml" title="Umpan Atom Wikipedia" href="/w/index.php?title=Istimewa:Perubahan_terbaru&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="//login.wikimedia.org"> </head> <body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-Reseptor_biokimia rootpage-Reseptor_biokimia skin-vector-2022 action-view"><a class="mw-jump-link" href="#bodyContent">Lompat ke isi</a> <div class="vector-header-container"> <header class="vector-header mw-header"> <div class="vector-header-start"> <nav class="vector-main-menu-landmark" aria-label="Situs"> <div id="vector-main-menu-dropdown" class="vector-dropdown vector-main-menu-dropdown vector-button-flush-left vector-button-flush-right" > <input type="checkbox" id="vector-main-menu-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-main-menu-dropdown" class="vector-dropdown-checkbox " aria-label="Menu utama" > <label id="vector-main-menu-dropdown-label" for="vector-main-menu-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">Menu utama</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">Menu utama</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">pindah ke bilah sisi</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-main-menu.unpin">sembunyikan</button> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> Navigasi </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-mainpage" class="mw-list-item"><a href="/wiki/Halaman_Utama" title="Kunjungi Halaman Utama [z]" accesskey="z"><span>Halaman Utama</span></a></li><li id="n-Daftar-isi" class="mw-list-item"><a href="/wiki/Wikipedia:Isi"><span>Daftar isi</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/Istimewa:Perubahan_terbaru" title="Daftar perubahan terbaru dalam wiki. [r]" accesskey="r"><span>Perubahan terbaru</span></a></li><li id="n-Artikel-pilihan" class="mw-list-item"><a href="/wiki/Wikipedia:Artikel_pilihan/Topik"><span>Artikel pilihan</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:Peristiwa_terkini" title="Temukan informasi tentang peristiwa terkini"><span>Peristiwa terkini</span></a></li><li id="n-newpage" class="mw-list-item"><a href="/wiki/Istimewa:Halaman_baru"><span>Halaman baru</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/Istimewa:Halaman_sembarang" title="Tampilkan sembarang halaman [x]" accesskey="x"><span>Halaman sembarang</span></a></li> </ul> </div> </div> <div id="p-Komunitas" class="vector-menu mw-portlet mw-portlet-Komunitas" > <div class="vector-menu-heading"> Komunitas </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-Warung-Kopi" class="mw-list-item"><a href="/wiki/Wikipedia:Warung_Kopi"><span>Warung Kopi</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Portal:Komunitas" title="Tentang proyek, apa yang dapat Anda lakukan, di mana untuk mencari sesuatu"><span>Portal komunitas</span></a></li><li id="n-help" class="mw-list-item"><a href="/wiki/Bantuan:Isi" title="Tempat mencari bantuan."><span>Bantuan</span></a></li> </ul> </div> </div> <div id="p-Wikipedia" class="vector-menu mw-portlet mw-portlet-Wikipedia" > <div class="vector-menu-heading"> Wikipedia </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-aboutsite" class="mw-list-item"><a href="/wiki/Wikipedia:Perihal"><span>Tentang Wikipedia</span></a></li><li id="n-Pancapilar" class="mw-list-item"><a href="/wiki/Wikipedia:Pancapilar"><span>Pancapilar</span></a></li><li id="n-Kebijakan" class="mw-list-item"><a href="/wiki/Wikipedia:Kebijakan_dan_pedoman"><span>Kebijakan</span></a></li><li id="n-Hubungi-kami" class="mw-list-item"><a href="/wiki/Wikipedia:Hubungi_kami"><span>Hubungi kami</span></a></li><li id="n-Bak-pasir" class="mw-list-item"><a href="/wiki/Wikipedia:Bak_pasir"><span>Bak pasir</span></a></li> </ul> </div> </div> <div id="p-Bagikan" class="vector-menu mw-portlet mw-portlet-Bagikan emptyPortlet" > <div class="vector-menu-heading"> Bagikan </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/Halaman_Utama" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="Wikipedia" src="/static/images/mobile/copyright/wikipedia-wordmark-en.svg" style="width: 7.5em; height: 1.125em;"> <img class="mw-logo-tagline" alt="Ensiklopedia Bebas" src="/static/images/mobile/copyright/wikipedia-tagline-id.svg" width="120" height="14" style="width: 7.5em; height: 0.875em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/Istimewa:Pencarian" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Cari di Wikipedia [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Pencarian</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Telusuri Wikipedia" aria-label="Telusuri Wikipedia" autocapitalize="sentences" title="Cari di Wikipedia [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Istimewa:Pencarian"> </div> <button class="cdx-button cdx-search-input__end-button">Cari</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="Perkakas pribadi"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="Tampilan"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="Change the appearance of the page's font size, width, and color" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="Tampilan" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">Tampilan</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_id.wikipedia.org&uselang=id" class=""><span>Menyumbang</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Istimewa:Buat_akun&returnto=Reseptor+%28biokimia%29" title="Anda dianjurkan untuk membuat akun dan masuk log; meskipun, hal itu tidak diwajibkan" class=""><span>Buat akun baru</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Istimewa:Masuk_log&returnto=Reseptor+%28biokimia%29" title="Anda disarankan untuk masuk log, meskipun hal itu tidak diwajibkan. [o]" accesskey="o" class=""><span>Masuk log</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Opsi lainnya" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Perkakas pribadi" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Perkakas pribadi</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="Menu pengguna" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_id.wikipedia.org&uselang=id"><span>Menyumbang</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Istimewa:Buat_akun&returnto=Reseptor+%28biokimia%29" title="Anda dianjurkan untuk membuat akun dan masuk log; meskipun, hal itu tidak diwajibkan"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Buat akun baru</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Istimewa:Masuk_log&returnto=Reseptor+%28biokimia%29" title="Anda disarankan untuk masuk log, meskipun hal itu tidak diwajibkan. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Masuk log</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Halaman penyunting yang telah keluar log <a href="/wiki/Bantuan:Pengantar" aria-label="Pelajari lebih lanjut tentang menyunting"><span>pelajari lebih lanjut</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Istimewa:Kontribusi_saya" title="Daftar suntingan yang dibuat dari alamat IP ini [y]" accesskey="y"><span>Kontribusi</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Istimewa:Pembicaraan_saya" title="Pembicaraan tentang suntingan dari alamat IP ini [n]" accesskey="n"><span>Pembicaraan</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Situs"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Daftar isi" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Daftar isi</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">pindah ke bilah sisi</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">sembunyikan</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Awal</div> </a> </li> <li id="toc-Jenis" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Jenis"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Jenis</span> </div> </a> <button aria-controls="toc-Jenis-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Gulingkan subbagian Jenis</span> </button> <ul id="toc-Jenis-sublist" class="vector-toc-list"> <li id="toc-Reseptor_ionotropik" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Reseptor_ionotropik"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Reseptor ionotropik</span> </div> </a> <ul id="toc-Reseptor_ionotropik-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reseptor_terhubung_protein_G" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Reseptor_terhubung_protein_G"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.2</span> <span>Reseptor terhubung protein G</span> </div> </a> <ul id="toc-Reseptor_terhubung_protein_G-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reseptor_tirosin_kinase" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Reseptor_tirosin_kinase"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.3</span> <span>Reseptor tirosin kinase</span> </div> </a> <ul id="toc-Reseptor_tirosin_kinase-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reseptor_inti" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Reseptor_inti"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.4</span> <span>Reseptor inti</span> </div> </a> <ul id="toc-Reseptor_inti-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Pengikatan_dan_aktivasi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Pengikatan_dan_aktivasi"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Pengikatan dan aktivasi</span> </div> </a> <button aria-controls="toc-Pengikatan_dan_aktivasi-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Gulingkan subbagian Pengikatan dan aktivasi</span> </button> <ul id="toc-Pengikatan_dan_aktivasi-sublist" class="vector-toc-list"> <li id="toc-Agonis_versus_antagonis" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Agonis_versus_antagonis"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Agonis versus antagonis</span> </div> </a> <ul id="toc-Agonis_versus_antagonis-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Aktivitas_konstitutif" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Aktivitas_konstitutif"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Aktivitas konstitutif</span> </div> </a> <ul id="toc-Aktivitas_konstitutif-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Teori_interaksi_reseptor_obat" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Teori_interaksi_reseptor_obat"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Teori interaksi reseptor obat</span> </div> </a> <button aria-controls="toc-Teori_interaksi_reseptor_obat-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Gulingkan subbagian Teori interaksi reseptor obat</span> </button> <ul id="toc-Teori_interaksi_reseptor_obat-sublist" class="vector-toc-list"> <li id="toc-Teori_pendudukan" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Teori_pendudukan"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Teori pendudukan</span> </div> </a> <ul id="toc-Teori_pendudukan-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Teori_laju" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Teori_laju"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.2</span> <span>Teori laju</span> </div> </a> <ul id="toc-Teori_laju-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Teori_induksi_fit" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Teori_induksi_fit"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.3</span> <span>Teori induksi fit</span> </div> </a> <ul id="toc-Teori_induksi_fit-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reseptor_cadangan" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Reseptor_cadangan"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.4</span> <span>Reseptor cadangan</span> </div> </a> <ul id="toc-Reseptor_cadangan-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Pengaturan_reseptor" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Pengaturan_reseptor"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Pengaturan reseptor</span> </div> </a> <ul id="toc-Pengaturan_reseptor-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Ligan" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ligan"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Ligan</span> </div> </a> <button aria-controls="toc-Ligan-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Gulingkan subbagian Ligan</span> </button> <ul id="toc-Ligan-sublist" class="vector-toc-list"> <li id="toc-Ekstraseluler" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Ekstraseluler"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.1</span> <span>Ekstraseluler</span> </div> </a> <ul id="toc-Ekstraseluler-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Intraseluler" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Intraseluler"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.2</span> <span>Intraseluler</span> </div> </a> <ul id="toc-Intraseluler-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Peran_dalam_kesehatan_dan_penyakit" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Peran_dalam_kesehatan_dan_penyakit"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Peran dalam kesehatan dan penyakit</span> </div> </a> <button aria-controls="toc-Peran_dalam_kesehatan_dan_penyakit-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Gulingkan subbagian Peran dalam kesehatan dan penyakit</span> </button> <ul id="toc-Peran_dalam_kesehatan_dan_penyakit-sublist" class="vector-toc-list"> <li id="toc-Dalam_kelainan_genetik" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Dalam_kelainan_genetik"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.1</span> <span>Dalam kelainan genetik</span> </div> </a> <ul id="toc-Dalam_kelainan_genetik-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Dalam_sistem_imun" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Dalam_sistem_imun"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2</span> <span>Dalam sistem imun</span> </div> </a> <ul id="toc-Dalam_sistem_imun-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Referensi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Referensi"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Referensi</span> </div> </a> <ul id="toc-Referensi-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Daftar isi" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Gulingkan daftar isi" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Gulingkan daftar isi</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Reseptor (biokimia)</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Pergi ke artikel dalam bahasa lain. Terdapat 51 bahasa" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-51" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">51 bahasa</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Reseptor_(biochemie)" title="Reseptor (biochemie) – Afrikaans" lang="af" hreflang="af" data-title="Reseptor (biochemie)" data-language-autonym="Afrikaans" data-language-local-name="Afrikaans" class="interlanguage-link-target"><span>Afrikaans</span></a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%85%D8%B3%D8%AA%D9%82%D8%A8%D9%84_(%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A1_%D8%AD%D9%8A%D9%88%D9%8A%D8%A9)" title="مستقبل (كيمياء حيوية) – Arab" lang="ar" hreflang="ar" data-title="مستقبل (كيمياء حيوية)" data-language-autonym="العربية" data-language-local-name="Arab" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Receptor_(biohemija)" title="Receptor (biohemija) – Bosnia" lang="bs" hreflang="bs" data-title="Receptor (biohemija)" data-language-autonym="Bosanski" data-language-local-name="Bosnia" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Receptor_(bioqu%C3%ADmica)" title="Receptor (bioquímica) – Katalan" lang="ca" hreflang="ca" data-title="Receptor (bioquímica)" data-language-autonym="Català" data-language-local-name="Katalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Receptor" title="Receptor – Cheska" lang="cs" hreflang="cs" data-title="Receptor" data-language-autonym="Čeština" data-language-local-name="Cheska" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Receptor" title="Receptor – Dansk" lang="da" hreflang="da" data-title="Receptor" data-language-autonym="Dansk" data-language-local-name="Dansk" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Rezeptor_(Biochemie)" title="Rezeptor (Biochemie) – Jerman" lang="de" hreflang="de" data-title="Rezeptor (Biochemie)" data-language-autonym="Deutsch" data-language-local-name="Jerman" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Receptor_(biochemistry)" title="Receptor (biochemistry) – Inggris" lang="en" hreflang="en" data-title="Receptor (biochemistry)" data-language-autonym="English" data-language-local-name="Inggris" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Ricevanto_(biologio)" title="Ricevanto (biologio) – Esperanto" lang="eo" hreflang="eo" data-title="Ricevanto (biologio)" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Receptor_celular" title="Receptor celular – Spanyol" lang="es" hreflang="es" data-title="Receptor celular" data-language-autonym="Español" data-language-local-name="Spanyol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Retseptor_(biokeemia)" title="Retseptor (biokeemia) – Esti" lang="et" hreflang="et" data-title="Retseptor (biokeemia)" data-language-autonym="Eesti" data-language-local-name="Esti" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Hartzaile_(biokimika)" title="Hartzaile (biokimika) – Basque" lang="eu" hreflang="eu" data-title="Hartzaile (biokimika)" data-language-autonym="Euskara" data-language-local-name="Basque" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%AF%DB%8C%D8%B1%D9%86%D8%AF%D9%87_(%D8%A8%DB%8C%D9%88%D8%B4%DB%8C%D9%85%DB%8C)" title="گیرنده (بیوشیمی) – Persia" lang="fa" hreflang="fa" data-title="گیرنده (بیوشیمی)" data-language-autonym="فارسی" data-language-local-name="Persia" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Reseptori_(biokemia)" title="Reseptori (biokemia) – Suomi" lang="fi" hreflang="fi" data-title="Reseptori (biokemia)" data-language-autonym="Suomi" data-language-local-name="Suomi" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/R%C3%A9cepteur_(biochimie)" title="Récepteur (biochimie) – Prancis" lang="fr" hreflang="fr" data-title="Récepteur (biochimie)" data-language-autonym="Français" data-language-local-name="Prancis" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Receptor_(bioqu%C3%ADmica)" title="Receptor (bioquímica) – Galisia" lang="gl" hreflang="gl" data-title="Receptor (bioquímica)" data-language-autonym="Galego" data-language-local-name="Galisia" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A7%D7%95%D7%9C%D7%98%D7%9F" title="קולטן – Ibrani" lang="he" hreflang="he" data-title="קולטן" data-language-autonym="עברית" data-language-local-name="Ibrani" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Receptor" title="Receptor – Kroasia" lang="hr" hreflang="hr" data-title="Receptor" data-language-autonym="Hrvatski" data-language-local-name="Kroasia" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-ht mw-list-item"><a href="https://ht.wikipedia.org/wiki/Resept%C3%A8" title="Reseptè – Kreol Haiti" lang="ht" hreflang="ht" data-title="Reseptè" data-language-autonym="Kreyòl ayisyen" data-language-local-name="Kreol Haiti" class="interlanguage-link-target"><span>Kreyòl ayisyen</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Receptor_(biok%C3%A9mia)" title="Receptor (biokémia) – Hungaria" lang="hu" hreflang="hu" data-title="Receptor (biokémia)" data-language-autonym="Magyar" data-language-local-name="Hungaria" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Recettore_(biochimica)" title="Recettore (biochimica) – Italia" lang="it" hreflang="it" data-title="Recettore (biochimica)" data-language-autonym="Italiano" data-language-local-name="Italia" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E5%8F%97%E5%AE%B9%E4%BD%93" title="受容体 – Jepang" lang="ja" hreflang="ja" data-title="受容体" data-language-autonym="日本語" data-language-local-name="Jepang" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%88%98%EC%9A%A9%EC%B2%B4" title="수용체 – Korea" lang="ko" hreflang="ko" data-title="수용체" data-language-autonym="한국어" data-language-local-name="Korea" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Wergir_(j%C3%AEnk%C3%AEmya)" title="Wergir (jînkîmya) – Kurdi" lang="ku" hreflang="ku" data-title="Wergir (jînkîmya)" data-language-autonym="Kurdî" data-language-local-name="Kurdi" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Receptorius_(molekul%C4%97)" title="Receptorius (molekulė) – Lituavi" lang="lt" hreflang="lt" data-title="Receptorius (molekulė)" data-language-autonym="Lietuvių" data-language-local-name="Lituavi" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/%C5%A0%C5%ABnu_receptors" title="Šūnu receptors – Latvi" lang="lv" hreflang="lv" data-title="Šūnu receptors" data-language-autonym="Latviešu" data-language-local-name="Latvi" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A0%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80_(%D0%B1%D0%B8%D0%BE%D1%85%D0%B5%D0%BC%D0%B8%D1%98%D0%B0)" title="Рецептор (биохемија) – Makedonia" lang="mk" hreflang="mk" data-title="Рецептор (биохемија)" data-language-autonym="Македонски" data-language-local-name="Makedonia" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%B1%E0%B4%BF%E0%B4%B8%E0%B4%AA%E0%B5%8D%E0%B4%B1%E0%B5%8D%E0%B4%B1%E0%B5%BC_(%E0%B4%9C%E0%B5%88%E0%B4%B5%E0%B4%B0%E0%B4%B8%E0%B4%A4%E0%B4%A8%E0%B5%8D%E0%B4%A4%E0%B5%8D%E0%B4%B0%E0%B4%82)" title="റിസപ്റ്റർ (ജൈവരസതന്ത്രം) – Malayalam" lang="ml" hreflang="ml" data-title="റിസപ്റ്റർ (ജൈവരസതന്ത്രം)" data-language-autonym="മലയാളം" data-language-local-name="Malayalam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Reseptor_(biokimia)" title="Reseptor (biokimia) – Melayu" lang="ms" hreflang="ms" data-title="Reseptor (biokimia)" data-language-autonym="Bahasa Melayu" data-language-local-name="Melayu" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Receptor_(biochemie)" title="Receptor (biochemie) – Belanda" lang="nl" hreflang="nl" data-title="Receptor (biochemie)" data-language-autonym="Nederlands" data-language-local-name="Belanda" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Reseptor_(biokjemi)" title="Reseptor (biokjemi) – Bokmål Norwegia" lang="nb" hreflang="nb" data-title="Reseptor (biokjemi)" data-language-autonym="Norsk bokmål" data-language-local-name="Bokmål Norwegia" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Receptor_(bioquimia)" title="Receptor (bioquimia) – Ositania" lang="oc" hreflang="oc" data-title="Receptor (bioquimia)" data-language-autonym="Occitan" data-language-local-name="Ositania" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Bia%C5%82ka_receptorowe" title="Białka receptorowe – Polski" lang="pl" hreflang="pl" data-title="Białka receptorowe" data-language-autonym="Polski" data-language-local-name="Polski" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Receptor_(bioqu%C3%ADmica)" title="Receptor (bioquímica) – Portugis" lang="pt" hreflang="pt" data-title="Receptor (bioquímica)" data-language-autonym="Português" data-language-local-name="Portugis" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Receptor_(biochimie)" title="Receptor (biochimie) – Rumania" lang="ro" hreflang="ro" data-title="Receptor (biochimie)" data-language-autonym="Română" data-language-local-name="Rumania" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9A%D0%BB%D0%B5%D1%82%D0%BE%D1%87%D0%BD%D1%8B%D0%B9_%D1%80%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80" title="Клеточный рецептор – Rusia" lang="ru" hreflang="ru" data-title="Клеточный рецептор" data-language-autonym="Русский" data-language-local-name="Rusia" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Receptor_(biohemija)" title="Receptor (biohemija) – Serbo-Kroasia" lang="sh" hreflang="sh" data-title="Receptor (biohemija)" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Kroasia" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Receptor_(cell_biology)" title="Receptor (cell biology) – Simple English" lang="en-simple" hreflang="en-simple" data-title="Receptor (cell biology)" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Receptor_(fyziol%C3%B3gia)" title="Receptor (fyziológia) – Slovak" lang="sk" hreflang="sk" data-title="Receptor (fyziológia)" data-language-autonym="Slovenčina" data-language-local-name="Slovak" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Receptor_(biokemija)" title="Receptor (biokemija) – Sloven" lang="sl" hreflang="sl" data-title="Receptor (biokemija)" data-language-autonym="Slovenščina" data-language-local-name="Sloven" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Receptori_(biokimi)" title="Receptori (biokimi) – Albania" lang="sq" hreflang="sq" data-title="Receptori (biokimi)" data-language-autonym="Shqip" data-language-local-name="Albania" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Receptor_(biohemija)" title="Receptor (biohemija) – Serbia" lang="sr" hreflang="sr" data-title="Receptor (biohemija)" data-language-autonym="Српски / srpski" data-language-local-name="Serbia" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Receptor" title="Receptor – Swedia" lang="sv" hreflang="sv" data-title="Receptor" data-language-autonym="Svenska" data-language-local-name="Swedia" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%AB%E0%B8%99%E0%B9%88%E0%B8%A7%E0%B8%A2%E0%B8%A3%E0%B8%B1%E0%B8%9A%E0%B8%84%E0%B8%A7%E0%B8%B2%E0%B8%A1%E0%B8%A3%E0%B8%B9%E0%B9%89%E0%B8%AA%E0%B8%B6%E0%B8%81" title="หน่วยรับความรู้สึก – Thai" lang="th" hreflang="th" data-title="หน่วยรับความรู้สึก" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tl mw-list-item"><a href="https://tl.wikipedia.org/wiki/Reseptor_(biyokimika)" title="Reseptor (biyokimika) – Tagalog" lang="tl" hreflang="tl" data-title="Reseptor (biyokimika)" data-language-autonym="Tagalog" data-language-local-name="Tagalog" class="interlanguage-link-target"><span>Tagalog</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Resept%C3%B6r_(biyokimya)" title="Reseptör (biyokimya) – Turki" lang="tr" hreflang="tr" data-title="Reseptör (biyokimya)" data-language-autonym="Türkçe" data-language-local-name="Turki" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A0%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80_(%D0%B1%D1%96%D0%BB%D0%BE%D0%BA)" title="Рецептор (білок) – Ukraina" lang="uk" hreflang="uk" data-title="Рецептор (білок)" data-language-autonym="Українська" data-language-local-name="Ukraina" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Th%E1%BB%A5_th%E1%BB%83_(h%C3%B3a_sinh)" title="Thụ thể (hóa sinh) – Vietnam" lang="vi" hreflang="vi" data-title="Thụ thể (hóa sinh)" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnam" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-vls mw-list-item"><a href="https://vls.wikipedia.org/wiki/Receptor" title="Receptor – West Flemish" lang="vls" hreflang="vls" data-title="Receptor" data-language-autonym="West-Vlams" data-language-local-name="West Flemish" class="interlanguage-link-target"><span>West-Vlams</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%8F%97%E4%BD%93_(%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6)" title="受体 (生物化学) – Tionghoa" lang="zh" hreflang="zh" data-title="受体 (生物化学)" data-language-autonym="中文" data-language-local-name="Tionghoa" class="interlanguage-link-target"><span>中文</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E5%8F%97%E5%AE%B9%E9%AB%94" title="受容體 – Kanton" lang="yue" hreflang="yue" data-title="受容體" data-language-autonym="粵語" data-language-local-name="Kanton" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q208467#sitelinks-wikipedia" title="Sunting pranala interwiki" class="wbc-editpage">Sunting pranala</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Ruang nama"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Reseptor_(biokimia)" title="Lihat halaman isi [c]" accesskey="c"><span>Halaman</span></a></li><li id="ca-talk" class="new vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Pembicaraan:Reseptor_(biokimia)&action=edit&redlink=1" rel="discussion" class="new" title="Pembicaraan halaman isi (halaman belum tersedia) [t]" accesskey="t"><span>Pembicaraan</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Ubah varian bahasa" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Bahasa Indonesia</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Tampilan"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Reseptor_(biokimia)"><span>Baca</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit" title="Sunting halaman ini [v]" accesskey="v"><span>Sunting</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit" title="Sunting kode sumber halaman ini [e]" accesskey="e"><span>Sunting sumber</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&action=history" title="Revisi sebelumnya dari halaman ini. [h]" accesskey="h"><span>Lihat riwayat</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Peralatan halaman"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Perkakas" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Perkakas</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Perkakas</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">pindah ke bilah sisi</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">sembunyikan</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Opsi lainnya" > <div class="vector-menu-heading"> Tindakan </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Reseptor_(biokimia)"><span>Baca</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit" title="Sunting halaman ini [v]" accesskey="v"><span>Sunting</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit" title="Sunting kode sumber halaman ini [e]" accesskey="e"><span>Sunting sumber</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&action=history"><span>Lihat riwayat</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Umum </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Istimewa:Pranala_balik/Reseptor_(biokimia)" title="Daftar semua halaman wiki yang memiliki pranala ke halaman ini [j]" accesskey="j"><span>Pranala balik</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Istimewa:Perubahan_terkait/Reseptor_(biokimia)" rel="nofollow" title="Perubahan terbaru halaman-halaman yang memiliki pranala ke halaman ini [k]" accesskey="k"><span>Perubahan terkait</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Istimewa:Halaman_istimewa" title="Daftar semua halaman istimewa [q]" accesskey="q"><span>Halaman istimewa</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&oldid=24976795" title="Pranala permanen untuk revisi halaman ini"><span>Pranala permanen</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&action=info" title="Informasi lanjut tentang halaman ini"><span>Informasi halaman</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Istimewa:Kutip&page=Reseptor_%28biokimia%29&id=24976795&wpFormIdentifier=titleform" title="Informasi tentang bagaimana mengutip halaman ini"><span>Kutip halaman ini</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Istimewa:UrlShortener&url=https%3A%2F%2Fid.wikipedia.org%2Fwiki%2FReseptor_%28biokimia%29"><span>Lihat URL pendek</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Istimewa:QrCode&url=https%3A%2F%2Fid.wikipedia.org%2Fwiki%2FReseptor_%28biokimia%29"><span>Unduh kode QR</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Cetak/ekspor </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Istimewa:Buku&bookcmd=book_creator&referer=Reseptor+%28biokimia%29"><span>Buat buku</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Istimewa:DownloadAsPdf&page=Reseptor_%28biokimia%29&action=show-download-screen"><span>Unduh versi PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Reseptor_(biokimia)&printable=yes" title="Versi cetak halaman ini [p]" accesskey="p"><span>Versi cetak</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> Dalam proyek lain </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Receptors" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q208467" title="Pranala untuk menghubungkan butir pada ruang penyimpanan data [g]" accesskey="g"><span>Butir di Wikidata</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Peralatan halaman"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Tampilan"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Tampilan</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">pindah ke bilah sisi</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">sembunyikan</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Dari Wikipedia bahasa Indonesia, ensiklopedia bebas</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="id" dir="ltr"><figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Berkas:Receptor_(Biochemistry).svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Receptor_%28Biochemistry%29.svg/220px-Receptor_%28Biochemistry%29.svg.png" decoding="async" width="220" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Receptor_%28Biochemistry%29.svg/330px-Receptor_%28Biochemistry%29.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Receptor_%28Biochemistry%29.svg/440px-Receptor_%28Biochemistry%29.svg.png 2x" data-file-width="512" data-file-height="308" /></a><figcaption>Contoh <b>reseptor</b> membran. <div><ol><li>Ligand, berlokasi di luar sel</li><li>Ligan terhubung ke protein reseptor spesifik berdasarkan bentuk situs aktif protein.</li><li>Reseptor melepaskan pembawa pesan kedua (second messenger) setelah ligan menempel ke reseptor.</li></ol></div></figcaption></figure> <p>Dalam <a href="/wiki/Biokimia" title="Biokimia">biokimia</a> dan <a href="/wiki/Farmakologi" title="Farmakologi">farmakologi</a>, <b>reseptor</b> adalah molekul <a href="/wiki/Protein" title="Protein">protein</a> yang menerima sinyal kimia dari luar sel.<sup id="cite_ref-hall_1-0" class="reference"><a href="#cite_note-hall-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Ketika sinyal kimia tersebut berikatan dengan reseptor, terjadi beberapa bentuk respons seluler, misalnya perubahan aktivitas listrik sel. Reseptor berlokasi di <a href="/wiki/Membran_sel" title="Membran sel">membran sel</a>, <a href="/wiki/Sitoplasma" title="Sitoplasma">sitoplasma</a>, dan <a href="/wiki/Nukleus" class="mw-redirect mw-disambig" title="Nukleus">nukleus</a>. Molekul pemberi sinyal yang melekat pada suatu reseptor disebut <a href="/wiki/Ligan_(biokimia)" title="Ligan (biokimia)">ligan</a>, yang dapat berupa suatu <a href="/wiki/Peptida" title="Peptida">peptida</a> atau molekul kecil lain seperti <a href="/wiki/Neurotransmiter" title="Neurotransmiter">neurotransmiter</a>, <a href="/wiki/Hormon" title="Hormon">hormon</a>, <a href="/wiki/Obat" title="Obat">obat</a>, atau <a href="/wiki/Toksin" title="Toksin">toksin</a>. </p><p>Reseptor dapat diklasifikasikan berdasarkan lokasinya. Reseptor transmembran meliputi reseptor terhubung dengan kanal ion (reseptor ionotropik), <a href="/wiki/Reseptor_terhubung-protein_G" class="mw-redirect" title="Reseptor terhubung-protein G">reseptor terhubung protein G (metabotropik)</a>, dan reseptor tirosin kinase.<sup id="cite_ref-hall_1-1" class="reference"><a href="#cite_note-hall-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Reseptor intraseluler ditemukan di dalam sel (di sitosol atau di inti sel).<sup id="cite_ref-hall_1-2" class="reference"><a href="#cite_note-hall-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Molekul yang berikatan secara alami untuk reseptor tertentu disebut sebagai ligan endogen. Misalnya ligan endogen untuk reseptor asetilkolin yaitu asetilkolin. </p><p>Setiap reseptor dihubungkan dengan jalur biokimia seluler spesifik. Banyak reseptor ditemukan di sebagian besar sel, dan masing-masing reseptor hanya mengikat dengan ligan struktur tertentu, seperti halnya gembok yang menerima kunci berbentuk khusus. Ketika ligan berikatan dengan reseptornya, ligan mengaktifkan jalur biokimia yang terkait reseptor. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Jenis">Jenis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=1" title="Sunting bagian: Jenis" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=1" title="Sunting kode sumber bagian: Jenis"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/Berkas:Transmembrane_receptor.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/48/Transmembrane_receptor.svg/220px-Transmembrane_receptor.svg.png" decoding="async" width="220" height="155" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/48/Transmembrane_receptor.svg/330px-Transmembrane_receptor.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/48/Transmembrane_receptor.svg/440px-Transmembrane_receptor.svg.png 2x" data-file-width="482" data-file-height="340" /></a><figcaption> Reseptor transmembran: E = ruang ekstraseluler; I = ruang intraseluler; P = membran plasma</figcaption></figure> <div class="mw-heading mw-heading3"><h3 id="Reseptor_ionotropik">Reseptor ionotropik</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=2" title="Sunting bagian: Reseptor ionotropik" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=2" title="Sunting kode sumber bagian: Reseptor ionotropik"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Reseptor terkait kanal ion teraktivasi ligan (reseptor ionotropik) biasanya menjadi target neurotransmiter cepat seperti reseptor asetilkolin nikotinik dan reseptor <a href="/wiki/Asam_gamma-aminobutirat" class="mw-redirect" title="Asam gamma-aminobutirat">GABA</a>. Aktivasi reseptor ini menghasilkan perubahan gerakan ion melintasi membran. Reseptor ionotropik memiliki struktur heteromer dengan setiap subunit terdiri dari domain pengikat ligan ekstraseluler dan domain transmembran. Domain transmembran pada gilirannya mencakup empat heliks alfa transmembran. Rongga pengikat ligan terletak di antarmuka antara subunit. </p> <div class="mw-heading mw-heading3"><h3 id="Reseptor_terhubung_protein_G">Reseptor terhubung protein G</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=3" title="Sunting bagian: Reseptor terhubung protein G" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=3" title="Sunting kode sumber bagian: Reseptor terhubung protein G"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Reseptor_terhubung-protein_G" class="mw-redirect" title="Reseptor terhubung-protein G">Reseptor terhubung protein G (reseptor metabotropik)</a> (GPCR) adalah keluarga reseptor terbesar dan termasuk reseptor untuk beberapa hormon dan neurotransmiter misalnya <a href="/w/index.php?title=Reseptor_dopamin&action=edit&redlink=1" class="new" title="Reseptor dopamin (halaman belum tersedia)">reseptor dopamin</a> dan <a href="/w/index.php?title=Reseptor_glutamat&action=edit&redlink=1" class="new" title="Reseptor glutamat (halaman belum tersedia)">reseptor glutamat</a>. GPCR terdiri dari tujuh heliks alfa transmembran. Lengkung yang menghubungkan heliks alfa membentuk domain ekstraseluler dan intraseluler. Situs pengikatan untuk ligan peptida yang lebih besar biasanya terletak di domain ekstraseluler, sedangkan situs pengikatan untuk ligan non-peptida yang lebih kecil sering terletak di antara tujuh heliks alfa dan satu lengkungan ekstraseluler.<sup id="cite_ref-pmid19912230_2-0" class="reference"><a href="#cite_note-pmid19912230-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Reseptor yang disebutkan di atas digabungkan ke sistem efektor intraseluler yang berbeda melalui protein G.<sup id="cite_ref-pmid=21873996_3-0" class="reference"><a href="#cite_note-pmid=21873996-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Reseptor_tirosin_kinase">Reseptor tirosin kinase</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=4" title="Sunting bagian: Reseptor tirosin kinase" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=4" title="Sunting kode sumber bagian: Reseptor tirosin kinase"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Reseptor yang terkait dengan kinase terdiri dari domain ekstraseluler yang mengandung situs pengikatan ligan dan domain intraseluler, sering kali dengan fungsi enzimatik, dihubungkan oleh heliks alfa transmembran tunggal. Contoh reseptor terkait kinase yaitu <a href="/wiki/Reseptor_insulin" title="Reseptor insulin">reseptor insulin</a>. </p> <div class="mw-heading mw-heading3"><h3 id="Reseptor_inti">Reseptor inti</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=5" title="Sunting bagian: Reseptor inti" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=5" title="Sunting kode sumber bagian: Reseptor inti"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Meskipun reseptor ini disebut reseptor inti, sebenarnya mereka terletak di <a href="/wiki/Sitoplasma" title="Sitoplasma">sitoplasma</a> dan bermigrasi ke <a href="/wiki/Inti_sel" title="Inti sel">inti</a> setelah mengikat dengan ligan. Reseptor terdiri dari daerah pengikat ligan ujung C, domain pengikat DNA inti (DBD) dan domain ujung N yang berisi wilayah <i>AF1</i> (fungsi aktivasi 1). Wilayah inti memiliki dua <i>zinc finger</i> yang bertanggung jawab untuk mengenali sekuens DNA khusus untuk reseptor ini. Ujung N berinteraksi dengan faktor-faktor transkripsi seluler lainnya dengan cara yang tidak bergantung ligan; dan tergantung pada interaksi ini, reseptor dapat memodifikasi pengikatan/aktivitas reseptor. Reseptor steroid dan hormon tiroid merupakan contoh dari reseptor tersebut.<sup id="cite_ref-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012_4-0" class="reference"><a href="#cite_note-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p><p>Reseptor membran dapat diisolasi dari membran sel dengan prosedur ekstraksi kompleks menggunakan <a href="/wiki/Ekstraksi_pelarut" title="Ekstraksi pelarut">pelarut</a>, <a href="/wiki/Deterjen" class="mw-redirect" title="Deterjen">deterjen</a>, dan/atau <a href="/wiki/Kromatografi_afinitas" title="Kromatografi afinitas">pemurnian afinitas</a>. </p><p>Struktur dan aksi reseptor dapat dipelajari dengan menggunakan metode biofisik seperti <a href="/wiki/Kristalografi_sinar-X" title="Kristalografi sinar-X">kristalografi sinar-X</a>, NMR, dichroism lingkaran, dan interferometri polarisasi ganda. <a href="/wiki/Simulasi_komputer" title="Simulasi komputer">Simulasi komputer</a> tentang perilaku dinamis dari reseptor telah digunakan untuk mendapatkan pemahaman tentang mekanisme aksi dari reseptor-reseptor inti. </p> <div class="mw-heading mw-heading2"><h2 id="Pengikatan_dan_aktivasi">Pengikatan dan aktivasi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=6" title="Sunting bagian: Pengikatan dan aktivasi" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=6" title="Sunting kode sumber bagian: Pengikatan dan aktivasi"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Pengikatan ligan adalah proses <a href="/wiki/Kesetimbangan_kimia" title="Kesetimbangan kimia">kesetimbangan</a>. Ligan mengikat reseptor dan memisahkan diri dari kompleks menurut hukum aksi massa. </p> <dl><dd><span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle {\overset {}{\underset {\text{(the brackets stand for concentrations)}}{[{\ce {Ligand}}]\cdot [{\ce {Receptor}}]{\ce {<=>[{K_{d}}]}}[{\text{Ligand-receptor complex}}]}}}}"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mrow class="MJX-TeXAtom-ORD"> <mover> <munder> <mrow> <mo stretchy="false">[</mo> <mrow class="MJX-TeXAtom-ORD"> <mtext>Ligand</mtext> </mrow> <mo stretchy="false">]</mo> <mo>⋅</mo> <mo stretchy="false">[</mo> <mrow class="MJX-TeXAtom-ORD"> <mtext>Receptor</mtext> </mrow> <mo stretchy="false">]</mo> <mrow class="MJX-TeXAtom-ORD"> <mrow class="MJX-TeXAtom-REL"> <mover> <mo>⇌</mo> <mpadded width="+0.667em" lspace="0.278em" voffset=".15em"> <mrow class="MJX-TeXAtom-ORD"> <msub> <mi>K</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>d</mi> </mrow> </msub> </mrow> </mpadded> </mover> </mrow> </mrow> <mo stretchy="false">[</mo> <mrow class="MJX-TeXAtom-ORD"> <mtext>Ligand-receptor complex</mtext> </mrow> <mo stretchy="false">]</mo> </mrow> <mtext>(the brackets stand for concentrations)</mtext> </munder> <mrow /> </mover> </mrow> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle {\overset {}{\underset {\text{(the brackets stand for concentrations)}}{[{\ce {Ligand}}]\cdot [{\ce {Receptor}}]{\ce {<=>[{K_{d}}]}}[{\text{Ligand-receptor complex}}]}}}}</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/59c3c80451a744bac62346222691014b5360d93e" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -3.171ex; width:50.183ex; height:7.676ex;" alt="{\displaystyle {\overset {}{\underset {\text{(the brackets stand for concentrations)}}{[{\ce {Ligand}}]\cdot [{\ce {Receptor}}]{\ce {<=>[{K_{d}}]}}[{\text{Ligand-receptor complex}}]}}}}"></span></dd></dl> <p>Salah satu ukuran seberapa baik suatu molekul cocok dengan suatu reseptor yaitu afinitas pengikatannya, yang berbanding terbalik dengan <a href="/wiki/Konstanta_disosiasi" title="Konstanta disosiasi">konstanta disosiasi</a> <i>K</i><sub><i>d</i></sub>. Kecocokan baik sesuai dengan afinitas tinggi dan rendah <i>K</i><sub><i>d.</i></sub> Respons biologis akhir (misal kaskade pembawa pesan kedua, kontraksi otot), hanya tercapai setelah sejumlah besar reseptor diaktifkan. </p> <div class="mw-heading mw-heading3"><h3 id="Agonis_versus_antagonis">Agonis versus antagonis</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=7" title="Sunting bagian: Agonis versus antagonis" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=7" title="Sunting kode sumber bagian: Agonis versus antagonis"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/Berkas:Efficacy_spectrum.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Efficacy_spectrum.png/320px-Efficacy_spectrum.png" decoding="async" width="320" height="123" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Efficacy_spectrum.png/480px-Efficacy_spectrum.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Efficacy_spectrum.png/640px-Efficacy_spectrum.png 2x" data-file-width="2436" data-file-height="937" /></a><figcaption> Spektrum efikasi ligan reseptor.</figcaption></figure> <p>Tidak semua ligan yang berikatan dengan reseptor akan mengaktifkan reseptor tersebut. Kelas ligan bisa dibagi menjadi: </p> <ul><li>Agonis (penuh), dapat mengaktifkan reseptor dan menghasilkan respons biologis yang kuat. Ligan endogen alami dengan efikasi terbesar untuk reseptor yang diberikan menurut definisi merupakan agonis penuh (efikasi/kemanjuran 100%).</li> <li>Agonis parsial, tidak mengaktifkan reseptor dengan efikasi maksimal, bahkan dengan pengikatan maksimal, menyebabkan respons parsial dibandingkan dengan agonis penuh (khasiat antara 0 dan 100%).</li> <li>Antagonis, mengikat reseptor tetapi tidak mengaktifkannya. Antagonis menghasilkan blokade reseptor, menghambat pengikatan agonis dan agonis terbalik (<i>inverse agonist</i>). Antagonis reseptor dapat bersifat terbalikkan, dan bersaing dengan agonis untuk reseptor (kompetitif), atau dapat bersifat antagonis ireversibel yang membentuk <a href="/wiki/Ikatan_kovalen" title="Ikatan kovalen">ikatan kovalen</a> (atau ikatan nonkovalen afinitas sangat tinggi) dengan reseptor dan mengebloknya secara total. <a href="/wiki/Omeprazol" title="Omeprazol">Omeprazol</a> merupakan <a href="/w/index.php?title=Inhibitor_pompa_proton&action=edit&redlink=1" class="new" title="Inhibitor pompa proton (halaman belum tersedia)">inhibitor pompa proton</a> merupakan contoh dari antagonis ireversibel. Efek dari antagonisme ireversibel hanya dapat dibalikkan dengan sintesis reseptor baru.</li> <li>Agonis terbalik (<i>inverse agonist</i>), mengurangi aktivitas reseptor dengan menghambat aktivitas konstitutifnya (efikasi negatif).</li> <li>Modulator alosterik: Agonis tidak mengikat ke situs pengikatan pada reseptor melainkan pada situs pengikatan alosterik tertentu, tempa memodifikasi efek agonis. Misalnya, <a href="/wiki/Benzodiazepin" class="mw-redirect" title="Benzodiazepin">benzodiazepin</a> (BZD) mengikat ke situs BZD pada reseptor GABA-A dan mempotensiasi efek GABA endogen.</li></ul> <p>Perhatikan bahwa gagasan agonisme dan antagonisme reseptor hanya mengacu pada interaksi antara reseptor dan ligan dan bukan pada efek biologisnya. </p> <div class="mw-heading mw-heading3"><h3 id="Aktivitas_konstitutif">Aktivitas konstitutif</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=8" title="Sunting bagian: Aktivitas konstitutif" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=8" title="Sunting kode sumber bagian: Aktivitas konstitutif"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Reseptor yang mampu menghasilkan respons biologis tanpa adanya ligan terikat dikatakan menunjukkan "aktivitas konstitutif".<sup id="cite_ref-Milligan_2003_5-0" class="reference"><a href="#cite_note-Milligan_2003-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> Aktivitas konstitutif dari reseptor dapat diblok oleh agonis terbalik. Obat anti-obesitas <a href="/w/index.php?title=Rimonabant&action=edit&redlink=1" class="new" title="Rimonabant (halaman belum tersedia)">rimonabant</a> dan <a href="/w/index.php?title=Taranabant&action=edit&redlink=1" class="new" title="Taranabant (halaman belum tersedia)">taranabant</a> merupakan agonis terbalik pada reseptor kanabinoid CB1 dan meskipun kedua obat menghasilkan penurunan berat badan yang signifikan, keduanya ditarik dari pasaran karena tingginya insiden depresi dan kecemasan, yang diyakini berkaitan dengan penghambatan aktivitas konstitutif reseptor kanabinoid. </p><p>Mutasi pada reseptor yang mengakibatkan peningkatan aktivitas konstitutif yang mendasari beberapa penyakit bawaan seperti <a href="/wiki/Pubertas_sebelum_waktunya" class="mw-redirect" title="Pubertas sebelum waktunya">pubertas dini</a> (karena mutasi pada reseptor LH) dan <a href="/wiki/Hipertiroidisme" title="Hipertiroidisme">hipertiroidisme</a> (karena mutasi pada reseptor hormon TSH). </p> <div class="mw-heading mw-heading2"><h2 id="Teori_interaksi_reseptor_obat">Teori interaksi reseptor obat</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=9" title="Sunting bagian: Teori interaksi reseptor obat" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=9" title="Sunting kode sumber bagian: Teori interaksi reseptor obat"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Teori_pendudukan">Teori pendudukan</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=10" title="Sunting bagian: Teori pendudukan" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=10" title="Sunting kode sumber bagian: Teori pendudukan"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Dogma utama farmakologi reseptor adalah bahwa efek obat berbanding lurus dengan jumlah reseptor yang ditempati. Selain itu, efek obat berhenti ketika obat terdisosiasi atau lepas ikatannya dari reseptor. </p><p>Ariëns dan Stephenson memperkenalkan istilah "afinitas" dan "efikasi" untuk menggambarkan aksi ligan yang terikat pada reseptor.<sup id="cite_ref-pmid13229418_6-0" class="reference"><a href="#cite_note-pmid13229418-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid13383117_7-0" class="reference"><a href="#cite_note-pmid13383117-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <ul><li><a href="/wiki/Konstanta_disosiasi" title="Konstanta disosiasi">Afinitas</a>: Kemampuan suatu obat untuk bergabung dengan reseptor untuk menciptakan kompleks reseptor-obat.</li> <li>Efikasi: Kemampuan kompleks reseptor obat untuk memulai respons.</li></ul> <div class="mw-heading mw-heading3"><h3 id="Teori_laju">Teori laju</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=11" title="Sunting bagian: Teori laju" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=11" title="Sunting kode sumber bagian: Teori laju"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Berbeda dengan Teori Pendudukan yang diterima secara luas, Teori Laju mengusulkan bahwa aktivasi reseptor berbanding lurus dengan jumlah total pertemuan obat dengan reseptornya per unit waktu. Aktivitas farmakologis berbanding lurus dengan tingkat disosiasi dan hubungan, <b>bukan</b> jumlah reseptor yang ditempati:<sup id="cite_ref-isbn0-12-643732-7_8-0" class="reference"><a href="#cite_note-isbn0-12-643732-7-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <ul><li>Agonis: Obat dengan asosiasi cepat dan disosiasi cepat.</li> <li>Agonis parsial: Obat dengan hubungan sedang dan disosiasi menengah.</li> <li>Antagonis: Obat dengan asosiasi cepat dan disosiasi lambat</li></ul> <div class="mw-heading mw-heading3"><h3 id="Teori_induksi_fit">Teori induksi fit</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=12" title="Sunting bagian: Teori induksi fit" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=12" title="Sunting kode sumber bagian: Teori induksi fit"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Ketika obat mendekati reseptor, reseptor mengubah konformasi tempat pengikatannya untuk menghasilkan kompleks reseptor obat. </p> <div class="mw-heading mw-heading3"><h3 id="Reseptor_cadangan">Reseptor cadangan</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=13" title="Sunting bagian: Reseptor cadangan" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=13" title="Sunting kode sumber bagian: Reseptor cadangan"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Dalam beberapa sistem reseptor (misalnya asetilkolin pada sambungan neuromuskuler pada otot polos), agonis mampu memperoleh respons maksimal pada tingkat hunian reseptor yang sangat rendah (<1%). Dengan demikian, sistem itu memiliki reseptor cadangan. Pengaturan ini menghasilkan ekonomi produksi dan pelepasan neurotransmitter.<sup id="cite_ref-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012_4-1" class="reference"><a href="#cite_note-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Pengaturan_reseptor">Pengaturan reseptor</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=14" title="Sunting bagian: Pengaturan reseptor" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=14" title="Sunting kode sumber bagian: Pengaturan reseptor"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Sel dapat meningkatkan atau mengurangi jumlah reseptor terhadap <a href="/wiki/Hormon" title="Hormon">hormon</a> atau <a href="/wiki/Neurotransmiter" title="Neurotransmiter">neurotransmitter</a> yang diberikan untuk mengubah sensitivitasnya terhadap molekul yang berbeda. Cara ini merupakan mekanisme <a href="/wiki/Loloh_balik" class="mw-redirect" title="Loloh balik">umpan balik</a> yang bertindak secara lokal. </p> <ul><li>Perubahan konformasi reseptor sedemikian rupa sehingga pengikatan agonis tidak mengaktifkan reseptor. Hal ini terlihat pada reseptor kanal ion.</li> <li>Pelepasan <a href="/wiki/Reseptor_terhubung-protein_G" class="mw-redirect" title="Reseptor terhubung-protein G">molekul efektor</a> terlihat pada reseptor terhubung protein G.</li> <li>Pengasingan reseptor (internalisasi)<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> misalnya dalam kasus reseptor hormon.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Ligan">Ligan</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=15" title="Sunting bagian: Ligan" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=15" title="Sunting kode sumber bagian: Ligan"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Ligan untuk reseptor sangat beragam. Contohnya termasuk:<sup id="cite_ref-boron_10-0" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Ekstraseluler">Ekstraseluler</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=16" title="Sunting bagian: Ekstraseluler" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=16" title="Sunting kode sumber bagian: Ekstraseluler"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <table class="wikitable"> <tbody><tr> <th>Reseptor </th> <th>Ligan </th> <th>Arus ion </th></tr> <tr> <td>Reseptor asetilkolin nikotinik </td> <td><a href="/w/index.php?title=Asetilkolin&action=edit&redlink=1" class="new" title="Asetilkolin (halaman belum tersedia)">Asetilkolin</a>, <a href="/wiki/Nikotin" title="Nikotin">nikotin</a> </td> <td>Na <sup>+</sup>, K <sup>+</sup>, Ca <sup>2+</sup><sup id="cite_ref-boron_10-1" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor glisn (GlyR) </td> <td><a href="/wiki/Glisina" title="Glisina">Glisin</a>, <a href="/wiki/Striknina" title="Striknina">strychnine</a> </td> <td>Cl <sup>-</sup> > HCO <sup>-</sup> <sub>3</sub><sup id="cite_ref-boron_10-2" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor GABA: GABA-A, GABA-C </td> <td><a href="/wiki/Asam_gamma-aminobutirat" class="mw-redirect" title="Asam gamma-aminobutirat">GABA</a> </td> <td>Cl <sup>-</sup> > HCO <sup>-</sup> <sub>3</sub><sup id="cite_ref-boron_10-3" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor glutamat: reseptor NMDA, reseptor AMPA, dan reseptor Kainate </td> <td><a href="/wiki/Asam_glutamat" title="Asam glutamat">Glutamat</a> </td> <td>Na <sup>+</sup>, K <sup>+</sup>, Ca <sup>2+</sup><sup id="cite_ref-boron_10-4" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor 5-HT3 </td> <td><a href="/wiki/Serotonin" title="Serotonin">Serotonin</a> </td> <td>Na <sup>+</sup>, K <sup>+</sup><sup id="cite_ref-boron_10-5" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor P2X </td> <td><a href="/wiki/Adenosina_trifosfat" title="Adenosina trifosfat">ATP</a> </td> <td>Ca <sup>2+</sup>, Na <sup>+</sup>, Mg <sup>2+</sup><sup id="cite_ref-boron_10-6" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> </tbody></table> <div class="mw-heading mw-heading3"><h3 id="Intraseluler">Intraseluler</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=17" title="Sunting bagian: Intraseluler" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=17" title="Sunting kode sumber bagian: Intraseluler"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <table class="wikitable"> <tbody><tr> <th>Reseptor </th> <th>Ligan </th> <th>Arus ion </th></tr> <tr> <td>Kanal ion nukleotida siklik </td> <td>cGMP (<a href="/wiki/Sistem_penglihatan" title="Sistem penglihatan">penglihatan</a>), <a href="/wiki/Adenosina_monofosfat_siklik" title="Adenosina monofosfat siklik">cAMP</a> dan cGTP (<a href="/wiki/Penciuman" title="Penciuman">penciuman</a>) </td> <td>Na <sup>+</sup>, K <sup>+</sup><sup id="cite_ref-boron_10-7" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor IP3 </td> <td>IP<sub id="mwAQU">3</sub> </td> <td>Ca <sup>2+</sup><sup id="cite_ref-boron_10-8" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor <a href="/wiki/Adenosina_trifosfat" title="Adenosina trifosfat">ATP</a> intraseluler </td> <td><a href="/wiki/Adenosina_trifosfat" title="Adenosina trifosfat">ATP</a> (menutup saluran) <sup id="cite_ref-boron_10-9" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td> <td>K <sup>+</sup><sup id="cite_ref-boron_10-10" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Reseptor ryanodine </td> <td>Ca <sup>2+</sup> </td> <td>Ca <sup>2+</sup><sup id="cite_ref-boron_10-11" class="reference"><a href="#cite_note-boron-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Peran_dalam_kesehatan_dan_penyakit">Peran dalam kesehatan dan penyakit</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=18" title="Sunting bagian: Peran dalam kesehatan dan penyakit" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=18" title="Sunting kode sumber bagian: Peran dalam kesehatan dan penyakit"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Dalam_kelainan_genetik">Dalam kelainan genetik</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=19" title="Sunting bagian: Dalam kelainan genetik" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=19" title="Sunting kode sumber bagian: Dalam kelainan genetik"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Banyak <a href="/wiki/Penyakit_genetik" title="Penyakit genetik">kelainan genetik</a> melibatkan cacat bawaan pada gen reseptor. Seringkali, sulit untuk menentukan apakah reseptor tidak berfungsi atau <a href="/wiki/Hormon" title="Hormon">hormon</a> diproduksi pada tingkat yang menurun; ini menimbulkan kelompok <a href="/wiki/Endokrinologi" title="Endokrinologi">kelainan endokrin</a> "pseudo-hypo-", di mana tampaknya ada penurunan tingkat hormonal sementara pada kenyataannya reseptor yang tidak merespon cukup terhadap hormon. </p> <div class="mw-heading mw-heading3"><h3 id="Dalam_sistem_imun">Dalam sistem imun</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=20" title="Sunting bagian: Dalam sistem imun" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=20" title="Sunting kode sumber bagian: Dalam sistem imun"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Reseptor utama dalam <a href="/wiki/Sistem_imun" title="Sistem imun">sistem imun</a> yaitu <a href="/wiki/Reseptor_pengenal_pola" title="Reseptor pengenal pola">reseptor pengenalan pola</a> (PRR), reseptor Toll-like (TLR), reseptor pembunuh diaktifkan dan reseptor pembunuh inhibitor (KAR dan KIR), reseptor komlemen, reseptor Fc, reseptor sel B dan <a href="/wiki/Reseptor_sel_T" title="Reseptor sel T">reseptor sel T</a>.<sup id="cite_ref-isbn0-7817-9543-5_11-0" class="reference"><a href="#cite_note-isbn0-7817-9543-5-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Referensi">Referensi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biokimia)&veaction=edit&section=21" title="Sunting bagian: Referensi" class="mw-editsection-visualeditor"><span>sunting</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biokimia)&action=edit&section=21" title="Sunting kode sumber bagian: Referensi"><span>sunting sumber</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r18833634">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width" style="column-width: 30em;"> <ol class="references"> <li id="cite_note-hall-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-hall_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-hall_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-hall_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><cite class="citation book">Hall, JE (2016). <i>Guyton and Hall Textbook of Medical Physiology</i>. Philadelphia, PA: Elsevier Saunders. hlm. 930–937. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Istimewa:Sumber_buku/978-1-4557-7005-2" title="Istimewa:Sumber buku/978-1-4557-7005-2">978-1-4557-7005-2</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Guyton+and+Hall+Textbook+of+Medical+Physiology&rft.place=Philadelphia%2C+PA&rft.pages=930-937&rft.pub=Elsevier+Saunders&rft.date=2016&rft.isbn=978-1-4557-7005-2&rft.au=Hall%2C+JE&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid19912230-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid19912230_2-0">^</a></b></span> <span class="reference-text"><cite class="citation journal"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2839258">"The impact of GPCR structures on pharmacology and structure-based drug design"</a>. <i>British Journal of Pharmacology</i>. <b>159</b> (5): 986–96. March 2010. <a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1476-5381.2009.00476.x">10.1111/j.1476-5381.2009.00476.x</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2839258">2839258</a> <span typeof="mw:File"><span title="Dapat diakses gratis"><img alt="alt=Dapat diakses gratis" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19912230">19912230</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Pharmacology&rft.atitle=The+impact+of+GPCR+structures+on+pharmacology+and+structure-based+drug+design&rft.volume=159&rft.issue=5&rft.pages=986-96&rft.date=2010-03&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2839258&rft_id=info%3Apmid%2F19912230&rft_id=info%3Adoi%2F10.1111%2Fj.1476-5381.2009.00476.x&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2839258&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid=21873996-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid=21873996_3-0">^</a></b></span> <span class="reference-text"><cite class="citation journal"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3177959">"Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers"</a>. <i>Nature Chemical Biology</i>. <b>7</b> (10): 740–7. August 2011. <a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnchembio.642">10.1038/nchembio.642</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3177959">3177959</a> <span typeof="mw:File"><span title="Dapat diakses gratis"><img alt="alt=Dapat diakses gratis" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/21873996">21873996</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+Chemical+Biology&rft.atitle=Inactive-state+preassembly+of+G%28q%29-coupled+receptors+and+G%28q%29+heterotrimers&rft.volume=7&rft.issue=10&rft.pages=740-7&rft.date=2011-08&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3177959&rft_id=info%3Apmid%2F21873996&rft_id=info%3Adoi%2F10.1038%2Fnchembio.642&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3177959&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012-4"><span class="mw-cite-backlink">^ <a href="#cite_ref-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012_4-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Rang_HP,_Dale_MM,_Ritter_JM,_Flower_RJ,_Henderson_G_2012_4-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><cite class="citation book"><a rel="nofollow" class="external text" href="https://archive.org/details/rangdalespharmac0000rang"><i>Rang & Dale's Pharmacology</i></a> (edisi ke-7th). Elsevier Churchill Livingstone. 2012. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Istimewa:Sumber_buku/978-0-7020-3471-8" title="Istimewa:Sumber buku/978-0-7020-3471-8">978-0-7020-3471-8</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Rang+%26+Dale%27s+Pharmacology&rft.edition=7th&rft.pub=Elsevier+Churchill+Livingstone&rft.date=2012&rft.isbn=978-0-7020-3471-8&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Frangdalespharmac0000rang&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Milligan_2003-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-Milligan_2003_5-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">"Constitutive activity and inverse agonists of G protein-coupled receptors: a current perspective". <i>Molecular Pharmacology</i>. <b>64</b> (6): 1271–6. December 2003. <a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1124%2Fmol.64.6.1271">10.1124/mol.64.6.1271</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/14645655">14645655</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Molecular+Pharmacology&rft.atitle=Constitutive+activity+and+inverse+agonists+of+G+protein-coupled+receptors%3A+a+current+perspective&rft.volume=64&rft.issue=6&rft.pages=1271-6&rft.date=2003-12&rft_id=info%3Adoi%2F10.1124%2Fmol.64.6.1271&rft_id=info%3Apmid%2F14645655&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid13229418-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid13229418_6-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">"Affinity and intrinsic activity in the theory of competitive inhibition. I. Problems and theory". <i>Archives Internationales De Pharmacodynamie Et De Therapie</i>. <b>99</b> (1): 32–49. September 1954. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/13229418">13229418</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Archives+Internationales+De+Pharmacodynamie+Et+De+Therapie&rft.atitle=Affinity+and+intrinsic+activity+in+the+theory+of+competitive+inhibition.+I.+Problems+and+theory&rft.volume=99&rft.issue=1&rft.pages=32-49&rft.date=1954-09&rft_id=info%3Apmid%2F13229418&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid13383117-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid13383117_7-0">^</a></b></span> <span class="reference-text"><cite class="citation journal"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1510558">"A modification of receptor theory"</a>. <i>British Journal of Pharmacology and Chemotherapy</i>. <b>11</b> (4): 379–93. December 1956. <a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1476-5381.1956.tb00006.x">10.1111/j.1476-5381.1956.tb00006.x</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1510558">1510558</a> <span typeof="mw:File"><span title="Dapat diakses gratis"><img alt="alt=Dapat diakses gratis" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/13383117">13383117</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Pharmacology+and+Chemotherapy&rft.atitle=A+modification+of+receptor+theory&rft.volume=11&rft.issue=4&rft.pages=379-93&rft.date=1956-12&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1510558&rft_id=info%3Apmid%2F13383117&rft_id=info%3Adoi%2F10.1111%2Fj.1476-5381.1956.tb00006.x&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1510558&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-isbn0-12-643732-7-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-isbn0-12-643732-7_8-0">^</a></b></span> <span class="reference-text"><cite class="citation book">Silverman RB (2004). "3.2.C Theories for Drug—Receptor Interactions". <a rel="nofollow" class="external text" href="https://archive.org/details/organicchemistry00silv_0"><i>The Organic Chemistry of Drug Design and Drug Action</i></a> (edisi ke-2nd). Amsterdam: Elsevier Academic Press. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Istimewa:Sumber_buku/0-12-643732-7" title="Istimewa:Sumber buku/0-12-643732-7">0-12-643732-7</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=3.2.C+Theories+for+Drug%E2%80%94Receptor+Interactions&rft.btitle=The+Organic+Chemistry+of+Drug+Design+and+Drug+Action&rft.place=Amsterdam&rft.edition=2nd&rft.pub=Elsevier+Academic+Press&rft.date=2004&rft.isbn=0-12-643732-7&rft.au=Silverman+RB&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Forganicchemistry00silv_0&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><cite class="citation journal">"Short-term desensitization of the angiotensin II receptor of bovinde adrenal glomerulosa cells corresponds to a shift from a high to low affinity state". <i>Endocrinology</i>. <b>135</b> (5): 2130–6. November 1994. <a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.135.5.2130">10.1210/en.135.5.2130</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Short-term+desensitization+of+the+angiotensin+II+receptor+of+bovinde+adrenal+glomerulosa+cells+corresponds+to+a+shift+from+a+high+to+low+affinity+state&rft.volume=135&rft.issue=5&rft.pages=2130-6&rft.date=1994-11&rft_id=info%3Adoi%2F10.1210%2Fen.135.5.2130&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-boron-10"><span class="mw-cite-backlink">^ <a href="#cite_ref-boron_10-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-boron_10-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-boron_10-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-boron_10-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-boron_10-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-boron_10-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-boron_10-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-boron_10-7"><sup><i><b>h</b></i></sup></a> <a href="#cite_ref-boron_10-8"><sup><i><b>i</b></i></sup></a> <a href="#cite_ref-boron_10-9"><sup><i><b>j</b></i></sup></a> <a href="#cite_ref-boron_10-10"><sup><i><b>k</b></i></sup></a> <a href="#cite_ref-boron_10-11"><sup><i><b>l</b></i></sup></a></span> <span class="reference-text"><cite class="citation book"><a rel="nofollow" class="external text" href="https://archive.org/details/medicalphysiolog0000boro"><i>Medical physiology: a cellular and molecular approach</i></a>. St. Louis, Mo: Elsevier Saunders. 2005. hlm. <a rel="nofollow" class="external text" href="https://archive.org/details/medicalphysiolog0000boro/page/90">90</a>. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Istimewa:Sumber_buku/1-4160-2328-3" title="Istimewa:Sumber buku/1-4160-2328-3">1-4160-2328-3</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Medical+physiology%3A+a+cellular+and+molecular+approach&rft.place=St.+Louis%2C+Mo&rft.pages=90&rft.pub=Elsevier+Saunders&rft.date=2005&rft.isbn=1-4160-2328-3&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fmedicalphysiolog0000boro&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-isbn0-7817-9543-5-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-isbn0-7817-9543-5_11-0">^</a></b></span> <span class="reference-text"><cite class="citation book"><i>Immunology</i>. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. 2008. hlm. 20. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Istimewa:Sumber_buku/0-7817-9543-5" title="Istimewa:Sumber buku/0-7817-9543-5">0-7817-9543-5</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Immunology&rft.place=Philadelphia&rft.pages=20&rft.pub=Wolters+Kluwer+Health%2FLippincott+Williams+%26+Wilkins&rft.date=2008&rft.isbn=0-7817-9543-5&rfr_id=info%3Asid%2Fid.wikipedia.org%3AReseptor+%28biokimia%29" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Diperoleh dari "<a dir="ltr" href="https://id.wikipedia.org/w/index.php?title=Reseptor_(biokimia)&oldid=24976795">https://id.wikipedia.org/w/index.php?title=Reseptor_(biokimia)&oldid=24976795</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Istimewa:Daftar_kategori" title="Istimewa:Daftar kategori">Kategori</a>: <ul><li><a href="/wiki/Kategori:Biologi_membran" title="Kategori:Biologi membran">Biologi membran</a></li><li><a href="/wiki/Kategori:Biologi_sel" title="Kategori:Biologi sel">Biologi sel</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> Halaman ini terakhir diubah pada 10 Desember 2023, pukul 05.33.</li> <li id="footer-info-copyright">Teks tersedia di bawah <a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.en">Lisensi Atribusi-BerbagiSerupa Creative Commons</a>; ketentuan tambahan mungkin berlaku. Lihat <a class="external text" href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use">Ketentuan Penggunaan</a> untuk rincian lebih lanjut.</li> </ul> <ul id="footer-places"> <li id="footer-places-privacy"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy">Kebijakan privasi</a></li> <li id="footer-places-about"><a href="/wiki/Wikipedia:Tentang">Tentang Wikipedia</a></li> <li id="footer-places-disclaimers"><a href="/wiki/Wikipedia:Penyangkalan_umum">Penyangkalan</a></li> <li id="footer-places-wm-codeofconduct"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct">Kode Etik</a></li> <li id="footer-places-developers"><a href="https://developer.wikimedia.org">Pengembang</a></li> <li id="footer-places-statslink"><a href="https://stats.wikimedia.org/#/id.wikipedia.org">Statistik</a></li> <li id="footer-places-cookiestatement"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement">Pernyataan kuki</a></li> <li id="footer-places-mobileview"><a href="//id.m.wikipedia.org/w/index.php?title=Reseptor_(biokimia)&mobileaction=toggle_view_mobile" class="noprint stopMobileRedirectToggle">Tampilan seluler</a></li> </ul> <ul id="footer-icons" class="noprint"> <li id="footer-copyrightico"><a href="https://wikimediafoundation.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><img src="/static/images/footer/wikimedia-button.svg" width="84" height="29" alt="Wikimedia Foundation" loading="lazy"></a></li> <li id="footer-poweredbyico"><a href="https://www.mediawiki.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><img src="/w/resources/assets/poweredby_mediawiki.svg" alt="Powered by MediaWiki" width="88" height="31" loading="lazy"></a></li> </ul> </footer> </div> </div> </div> <div class="vector-settings" id="p-dock-bottom"> <ul></ul> </div><script>(RLQ=window.RLQ||[]).push(function(){mw.config.set({"wgHostname":"mw-web.codfw.main-6b7f745dd4-zvhvk","wgBackendResponseTime":140,"wgPageParseReport":{"limitreport":{"cputime":"0.201","walltime":"0.265","ppvisitednodes":{"value":752,"limit":1000000},"postexpandincludesize":{"value":21364,"limit":2097152},"templateargumentsize":{"value":115,"limit":2097152},"expansiondepth":{"value":8,"limit":100},"expensivefunctioncount":{"value":0,"limit":500},"unstrip-depth":{"value":0,"limit":20},"unstrip-size":{"value":21383,"limit":5000000},"entityaccesscount":{"value":0,"limit":400},"timingprofile":["100.00% 176.161 1 -total"," 77.22% 136.037 1 Templat:Reflist"," 31.85% 56.108 5 Templat:Cite_book"," 18.77% 33.074 6 Templat:Cite_journal"," 13.87% 24.428 1 Templat:Ordered_list"," 1.40% 2.466 1 Templat:Main_other"]},"scribunto":{"limitreport-timeusage":{"value":"0.073","limit":"10.000"},"limitreport-memusage":{"value":2602797,"limit":52428800}},"cachereport":{"origin":"mw-web.codfw.main-f69cdc8f6-g5pcr","timestamp":"20241124130414","ttl":2592000,"transientcontent":false}}});});</script> <script type="application/ld+json">{"@context":"https:\/\/schema.org","@type":"Article","name":"Reseptor (biokimia)","url":"https:\/\/id.wikipedia.org\/wiki\/Reseptor_(biokimia)","sameAs":"http:\/\/www.wikidata.org\/entity\/Q208467","mainEntity":"http:\/\/www.wikidata.org\/entity\/Q208467","author":{"@type":"Organization","name":"Kontributor dari proyek Wikimedia."},"publisher":{"@type":"Organization","name":"Wikimedia Foundation, Inc.","logo":{"@type":"ImageObject","url":"https:\/\/www.wikimedia.org\/static\/images\/wmf-hor-googpub.png"}},"datePublished":"2012-06-01T05:35:35Z","dateModified":"2023-12-10T05:33:41Z","image":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/0\/0e\/Receptor_%28Biochemistry%29.svg","headline":"Molekul Protein Penerima Sinyal Kimia"}</script> </body> </html>