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PSB - The Partnership for Structural Biology - Grenoble

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</div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-bf0280e elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="bf0280e" data-element_type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-52f91d6" data-id="52f91d6" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-967e96c elementor-widget elementor-widget-heading" data-id="967e96c" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h1 class="elementor-heading-title elementor-size-default">The Partnership for Structural Biology</h1> </div> </div> <div class="elementor-element elementor-element-c5d12e3 elementor-widget elementor-widget-heading" data-id="c5d12e3" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">A Great Environment for Great Science</h2> </div> </div> <div class="elementor-element elementor-element-03eb610 elementor-widget elementor-widget-text-editor" data-id="03eb610" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p><strong>The Partnership for Structural Biology (PSB)</strong> in Grenoble is a collaborative research initiative established by a Memorandum of Understanding in 2002. The PSB brings together several major European research institutes to advance the field of structural biology: the European Molecular Biology Laboratory (<a href="https://www.embl.org/sites/grenoble/" target="_blank" rel="noopener noreferrer nofollow">EMBL</a>), the European Synchrotron Radiation Facility (<a href="https://www.esrf.fr/" target="_blank" rel="noopener noreferrer nofollow">ESRF</a>), the Institut de Biologie Structurale (<a href="https://www.ibs.fr/" target="_blank" rel="noopener noreferrer nofollow">IBS</a>), and the Institut Laue Langevin (<a href="https://www.ill.eu/" target="_blank" rel="noopener noreferrer nofollow">ILL</a>), all located on the European Photon and Neutron (EPN) campus.</p> </div> </div> <div class="elementor-element elementor-element-e3bf950 elementor-align-right elementor-widget elementor-widget-button" data-id="e3bf950" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://www.psb-grenoble.eu/mission-short-description/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Read more</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-65ea99b elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="65ea99b" data-element_type="section" data-settings="{&quot;stretch_section&quot;:&quot;section-stretched&quot;,&quot;background_background&quot;:&quot;classic&quot;}"> <div class="elementor-background-overlay"></div> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7a3fed1" data-id="7a3fed1" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-039c3d6 elementor-widget elementor-widget-heading" data-id="039c3d6" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Upcoming Events</h2> </div> </div> <div class="elementor-element elementor-element-90a7f65 elementor-widget elementor-widget-shortcode" data-id="90a7f65" data-element_type="widget" data-widget_type="shortcode.default"> <div class="elementor-widget-container"> <div class="elementor-shortcode"><div class="homeevenement"><div class="agenda-bloc-evenment"><a href="https://www.psb-grenoble.eu/agenda/7th-international-symposium-on-diffraction-structural-biology-isdsb2025/" ><img fetchpriority="high" fetchpriority="high" width="600" height="400" src="https://www.psb-grenoble.eu/wp-content/uploads/2025/01/isdsb2025-header-200-600x400.jpg" class="attachment-eventimage size-eventimage wp-post-image" alt="" decoding="async" /></a><p class="agenda-date-event">5 - 7 May 2025</p><h3>7th International Symposium on Diffraction Structural Biology (ISDSB2025)</h3><div class="agenda-content">The 7th edition of the symposium (ISDSB25) will be held from 5th – 7th May, 2025 at the European Photon...</div><a href="https://www.psb-grenoble.eu/agenda/7th-international-symposium-on-diffraction-structural-biology-isdsb2025/" class="readmore"> Read more </a></div><div class="agenda-bloc-evenment"><a href="https://www.psb-grenoble.eu/agenda/psb-symposium-machine-learning-in-cellular-structural-biology/" ><img width="600" height="400" src="https://www.psb-grenoble.eu/wp-content/uploads/2024/12/website-pichr-600x400.jpg" class="attachment-eventimage size-eventimage wp-post-image" alt="" decoding="async" /></a><p class="agenda-date-event">26- 27 June 2025</p><h3>PSB Symposium &#8220;Machine Learning in Cellular Structural Biology</h3><div class="agenda-content">The 5th edition of the PSB biennial Symposium will be themed &#8220;Machine Learning in Cellular Structural Biology&#8221;, and the meeting...</div><a href="https://www.psb-grenoble.eu/agenda/psb-symposium-machine-learning-in-cellular-structural-biology/" class="readmore"> Read more </a></div></div></div> </div> </div> <div class="elementor-element elementor-element-f0653b9 elementor-align-right elementor-widget elementor-widget-button" data-id="f0653b9" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://www.psb-grenoble.eu/upcoming-psb-events/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">More events</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-0601dff elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="0601dff" data-element_type="section" data-settings="{&quot;stretch_section&quot;:&quot;section-stretched&quot;,&quot;background_background&quot;:&quot;classic&quot;}"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-891eb6b" data-id="891eb6b" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-6bc13ac elementor-widget elementor-widget-heading" data-id="6bc13ac" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Scientific Highlights</h2> </div> </div> <div class="elementor-element elementor-element-56c3961 elementor-grid-3 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-posts--thumbnail-top elementor-card-shadow-yes elementor-posts__hover-gradient elementor-widget elementor-widget-posts" data-id="56c3961" data-element_type="widget" data-settings="{&quot;cards_columns&quot;:&quot;3&quot;,&quot;cards_columns_tablet&quot;:&quot;2&quot;,&quot;cards_columns_mobile&quot;:&quot;1&quot;,&quot;cards_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:35,&quot;sizes&quot;:[]},&quot;cards_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;cards_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}" data-widget_type="posts.cards"> <div class="elementor-widget-container"> <div class="elementor-posts-container elementor-posts elementor-posts--skin-cards elementor-grid"> <article class="elementor-post elementor-grid-item post-1535 post type-post status-publish 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href="https://www.psb-grenoble.eu/2024/07/30/targeting-dna-repair-pathway-in-cancers-through-the-lens-of-melanoma-antigens/" > Targeting DNA repair pathway in cancers – through the lens of melanoma antigens </a> </h3> <div class="elementor-post__excerpt"> <p>Our genetic material is highly susceptible to mutations, either spontaneously or triggered by external stimuli such as UV and chemical</p> </div> <a class="elementor-post__read-more" href="https://www.psb-grenoble.eu/2024/07/30/targeting-dna-repair-pathway-in-cancers-through-the-lens-of-melanoma-antigens/" aria-label="Read more about Targeting DNA repair pathway in cancers – through the lens of melanoma antigens" tabindex="-1" > Read More » </a> </div> <div class="elementor-post__meta-data"> <span class="elementor-post-date"> July 30, 2024 </span> </div> </div> </article> <article class="elementor-post elementor-grid-item post-1538 post type-post status-publish format-standard has-post-thumbnail hentry 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https://www.psb-grenoble.eu/wp-content/uploads/2024/08/esrf-psb-newsletter-july2024-figure.jpg 996w" sizes="(max-width: 768px) 100vw, 768px" /></div></a> <div class="elementor-post__text"> <h3 class="elementor-post__title"> <a href="https://www.psb-grenoble.eu/2024/07/30/how-does-the-body-prevent-multiple-sperm-from-fertilizing-an-egg/" > How does the body prevent multiple sperm from fertilizing an egg? </a> </h3> <div class="elementor-post__excerpt"> <p>According to the World Health Organization (WHO) around 15% of couples worldwide face infertility, with some cases linked to mutations</p> </div> <a class="elementor-post__read-more" href="https://www.psb-grenoble.eu/2024/07/30/how-does-the-body-prevent-multiple-sperm-from-fertilizing-an-egg/" aria-label="Read more about How does the body prevent multiple sperm from fertilizing an egg?" tabindex="-1" > Read More » </a> </div> <div class="elementor-post__meta-data"> <span class="elementor-post-date"> July 30, 2024 </span> </div> </div> </article> <article class="elementor-post elementor-grid-item post-1543 post type-post status-publish format-standard has-post-thumbnail hentry category-scientific-highlights-cat"> <div class="elementor-post__card"> <a class="elementor-post__thumbnail__link" href="https://www.psb-grenoble.eu/2024/07/30/how-is-the-production-of-reactive-oxygen-species-activated-in-nadph-oxidase-membrane-enzymes-lessons-from-the-structure-of-a-bacterial-homologue/" tabindex="-1" ><div class="elementor-post__thumbnail"><img loading="lazy" loading="lazy" width="768" height="541" src="https://www.psb-grenoble.eu/wp-content/uploads/2024/08/fieschi-figure1-2-768x541.jpg" class="attachment-medium_large size-medium_large wp-image-1551" alt="" decoding="async" srcset="https://www.psb-grenoble.eu/wp-content/uploads/2024/08/fieschi-figure1-2-768x541.jpg 768w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/fieschi-figure1-2-300x212.jpg 300w, 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srcset="https://www.psb-grenoble.eu/wp-content/uploads/2024/08/highlight-ill-psb-fig2-final-768x476.jpg 768w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/highlight-ill-psb-fig2-final-300x186.jpg 300w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/highlight-ill-psb-fig2-final.jpg 1000w" sizes="(max-width: 768px) 100vw, 768px" /></div></a> <div class="elementor-post__text"> <h3 class="elementor-post__title"> <a href="https://www.psb-grenoble.eu/2024/07/30/tryptophan-synthase-crystals-grown-on-the-international-space-station-facilitate-novel-neutron-crystal-structure/" > Tryptophan synthase crystals grown on the International Space Station facilitate novel neutron crystal structure </a> </h3> <div class="elementor-post__excerpt"> <p>Single-crystal neutron diffraction is a powerful technique in structural biology that can accurately visualize the hydrogen atom positions in biomacromolecules.</p> </div> <a class="elementor-post__read-more" 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of RNA sequences (introns)</p> </div> <a class="elementor-post__read-more" href="https://www.psb-grenoble.eu/2024/07/30/perturbing-the-active-site-of-splicing-machines-as-a-new-strategy-for-splicing-inhibition/" aria-label="Read more about Perturbing the active site of splicing machines as a new strategy for splicing inhibition" tabindex="-1" > Read More » </a> </div> <div class="elementor-post__meta-data"> <span class="elementor-post-date"> July 30, 2024 </span> </div> </div> </article> <article class="elementor-post elementor-grid-item post-1558 post type-post status-publish format-standard has-post-thumbnail hentry category-scientific-highlights-cat"> <div class="elementor-post__card"> <a class="elementor-post__thumbnail__link" href="https://www.psb-grenoble.eu/2024/07/30/news-from-the-m4d-platform/" tabindex="-1" ><div class="elementor-post__thumbnail"><img loading="lazy" loading="lazy" width="768" height="768" src="https://www.psb-grenoble.eu/wp-content/uploads/2024/08/m4d-logo-768x768.jpg" class="attachment-medium_large size-medium_large wp-image-1560" alt="" decoding="async" srcset="https://www.psb-grenoble.eu/wp-content/uploads/2024/08/m4d-logo-768x768.jpg 768w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/m4d-logo-300x300.jpg 300w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/m4d-logo-150x150.jpg 150w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/m4d-logo-60x60.jpg 60w, https://www.psb-grenoble.eu/wp-content/uploads/2024/08/m4d-logo.jpg 1000w" sizes="(max-width: 768px) 100vw, 768px" /></div></a> <div class="elementor-post__text"> <h3 class="elementor-post__title"> <a href="https://www.psb-grenoble.eu/2024/07/30/news-from-the-m4d-platform/" > News from the M4D platform </a> </h3> <div class="elementor-post__excerpt"> <p>We are glad to announce 2 major pieces of equipment have been integrated at the M4D platform. 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