Essential cancer medicines

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href="/what-we-do/member-benefits/learning-and-development/patient-group-mentoring-programme" data-drupal-link-system-path="node/25481">Patient Group Mentoring programme</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> </ul> </div> </div> </li> <li class="menu-item menu-item--expanded menu-dropdown__content"> <a href="/what-we-do/member-benefits/regional-focus" data-drupal-link-system-path="node/16885">Regional focus</a> <a class="show-menu flex"> <qz-icon slot="end" name="plus-icon" class="plus-icon"></qz-icon> <qz-icon slot="end" name="minus-icon" class="minus-icon hidden"></qz-icon> </a> <div class="menu-dropdown__items hidden"> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-2 menu-type-default"> <ul class="menu menu-level-wrapper menu-level-3"> <li class="menu-item menu-item-wrapper"> <a 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</div> </li> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/sharing-knowledge/virtual-dialogues/uhc-and-cancer-control-series" data-drupal-link-system-path="node/33957">UHC and cancer control series</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> </ul> </div> </div> </li> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/member-benefits/learning-and-development/fellowships" data-drupal-link-system-path="node/17202">Fellowships</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-2 menu-type-default"> </div> </li> <li class="menu-item menu-item--expanded menu-dropdown__content"> <a href="/what-we-do/sharing-knowledge/tnm" data-drupal-link-system-path="node/16693">TNM</a> <a class="show-menu flex"> <qz-icon slot="end" name="plus-icon" class="plus-icon"></qz-icon> <qz-icon slot="end" name="minus-icon" class="minus-icon 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data-drupal-link-system-path="node/22993">E-learning</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> <li class="menu-item menu-item-wrapper"> <a href="/resources/tnm-help-desk" data-drupal-link-system-path="node/33829">TNM Help Desk</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/sharing-knowledge/tnm/essential-tnm" data-drupal-link-system-path="node/23902">Essential TNM</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> </ul> </div> </div> </li> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/sharing-knowledge/global-initiative-cancer-registries-gicr" data-drupal-link-system-path="node/20378">Global Initiative for Cancer Registries (GICR)</a> <div 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hidden"> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-2 menu-type-default"> <ul class="menu menu-level-wrapper menu-level-3"> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/thematic-areas/tobacco-control/world-no-tobacco-day" data-drupal-link-system-path="node/28126">World No Tobacco Day</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> </ul> </div> </div> </li> <li class="menu-item menu-item--expanded menu-dropdown__content"> <a href="/what-we-do/thematic-areas/universal-health-coverage-uhc" data-drupal-link-system-path="node/25128">Universal health coverage (UHC)</a> <a class="show-menu flex"> <qz-icon slot="end" name="plus-icon" class="plus-icon"></qz-icon> <qz-icon slot="end" name="minus-icon" class="minus-icon hidden"></qz-icon> </a> <div class="menu-dropdown__items hidden"> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-2 menu-type-default"> <ul class="menu menu-level-wrapper menu-level-3"> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/thematic-areas/universal-health-coverage-uhc/2023-high-level-meeting-universal-health" data-drupal-link-system-path="node/33892">2023 High-Level Meeting on Universal Health Coverage</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-3 menu-type-default"> </div> </li> </ul> </div> </div> </li> <li class="menu-item menu-item-wrapper"> <a href="/what-we-do/thematic-areas/women-and-cancer" data-drupal-link-system-path="node/33853">Women and cancer</a> <div class="menu_link_content menu-link-contentmain view-mode-default menu-dropdown menu-dropdown-2 menu-type-default"> </div> </li> </ul> <div><article> <img loading="lazy" width="483" height="322" src="data:image/webp;base64,UklGRvwAAABXRUJQVlA4IPAAAADQBACdASoVAA4APm0qkkWkIqGYBABABsS2AF2ZQFwBfOTY9nEQszttCQ3Onji8AAD++ASM8neLM4ZGZErWeEAFDCnBV4LWg6xSps2jVu2PZhkoLH5b4J0x+xO0OTPI7yGOaOnGSxSSyjO2d7Qs3pNrykW1NFYOzFRGur2xG+gAfcCA9FMkqnbbNRRmk6QblW5W4uCkSl1a9UXVlWRPwN5qRXiWf6+eh4/k3x8lE8Y8zSJdFk5HkmrBkaeeP/Al9vpfSoeVLv1j/P4P79lcEzQETPw80Lt+vqGSzJVrNE1+X7orntPuMrFLIsX9KUhqAAA=" alt="Woman examines patient in front of mammography machine" class="lazyload" data-src="/sites/default/files/styles/hero_extra_large/public/2023-02/RS28556_2021-FUCAM-Mexico-Cancer-Control%2089.JPG.webp?itok=ZDRAt5Xi" data-srcset="/sites/default/files/styles/hero_placeholder/public/2023-02/RS28556_2021-FUCAM-Mexico-Cancer-Control%2089.JPG.webp?itok=NuSH6o0m 21w, /sites/default/files/styles/hero_small/public/2023-02/RS28556_2021-FUCAM-Mexico-Cancer-Control%2089.JPG.webp?itok=VVrLddZ_ 483w, /sites/default/files/styles/hero_medium/public/2023-02/RS28556_2021-FUCAM-Mexico-Cancer-Control%2089.JPG.webp?itok=daZJfg21 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href="/" class="text-navy-dark"> Home </a> </li> <li class="inline-block tracking-widest"> <a href="/what-we-do/thematic-areas" class="text-navy-dark"> What we do | Thematic areas </a> </li> <li class="inline-block tracking-widest"> Essential Cancer Medicines </li> </ol> </nav> <span class="flex flex-col lg:grid lg:grid-cols-12 pt-5 text-white"> <span class="page--text-preview lg:pb-12 lg:col-span-7 lg:pr-14 lg:pt-6"> <h1 class="h1-small font-normal lg:font-semibold pb-3.5"><span>Essential cancer medicines</span> </h1> <p>Essential medicines are defined as those that “satisfy the priority health care needs of the population”. </p> </span> <span class="pt-9 lg:pt-0 lg:col-span-5 relative"> <span class="lg:absolute"><article> <img loading="lazy" width="483" height="322" src="data:image/webp;base64,UklGRrAAAABXRUJQVlA4IKQAAADwAwCdASoVAA4APm0skkWkIqGYBABABsSyAE6AEWzhYQ1ANQvv04AAAP60Iwp8H7sOHlgETcNk9caGECnA85RbAQFVtPBp7vZVjzETW0E1CXQL8VQtPAQstyKZHUnCAxUbIGrco3NbeNpH0viIjpABqQLkl4R/fI5sFH3eZ7zYzVUpKzh8Mbrp4oG/LUGEKBjr8EJ84ucOyfqsMMEOr0WpSmNwAA==" alt="world-map-essential-medicines" title="world-map-essential-medicines" class="lazyload" data-src="/sites/default/files/styles/hero_extra_large/public/thumbnails/image/world-1185076_1280.png.webp?itok=wbNCs6Np" data-srcset="/sites/default/files/styles/hero_placeholder/public/thumbnails/image/world-1185076_1280.png.webp?itok=BvozDJGr 21w, /sites/default/files/styles/hero_small/public/thumbnails/image/world-1185076_1280.png.webp?itok=dc5jZ69t 483w, /sites/default/files/styles/hero_medium/public/thumbnails/image/world-1185076_1280.png.webp?itok=7FboWtXw 777w, /sites/default/files/styles/hero_large/public/thumbnails/image/world-1185076_1280.png.webp?itok=ioHXrEfp 1050w, /sites/default/files/styles/hero_extra_large/public/thumbnails/image/world-1185076_1280.png.webp?itok=wbNCs6Np 1470w, /sites/default/files/styles/hero_full/public/thumbnails/image/world-1185076_1280.png.webp?itok=6H-VCEJV 1932w, /sites/default/files/styles/hero_4k/public/thumbnails/image/world-1185076_1280.png.webp?itok=TeSVEj8I 3840w" data-sizes="auto" /> </article> </span> </span> </span> </qz-section> </div> <div> <qz-section width="content" class="content-navbar-on-page bg-navy-light text-white sticky top-[70px] lg:top-[78px] z-[15]"> <div class="content-navbar"> <div class="content-navbar__dropdown"> <span>Go to section</span> <qz-icon name="caret-down" width="8" height="4" class="ml-4"></qz-icon> <qz-icon name="caret-up" width="8" height="4" class="hidden ml-4"></qz-icon> </div> <ul class="content-navbar__menu"> <li> <a href="#49453" data-drupal-anchor-id="49453" class="content-navbar__anchor">Improving access to essential cancer medicines</a> </li> <li> <a href="#49455" data-drupal-anchor-id="49455" class="content-navbar__anchor">National Lists of Essential Medicines</a> </li> <li> <a href="#49456" data-drupal-anchor-id="49456" class="content-navbar__anchor">The role of UICC and its members</a> </li> </ul> </div> </qz-section> <div> <div> <div> <qz-section spacing="bottom-small top-small"> <div class="text"> <div><p>Cancer is the second leading cause of death globally. Ensuring the availability of medicines for treatment – including chemotherapy, immunotherapy, antibiotics and for pain relief – is crucial. Many countries around the world, however, struggle with issues of access, availability and affordability of quality-assured essential medicines for cancer treatment.</p> <p>Essential medicines are defined as those that “satisfy the priority health care needs of the population”. They are selected with regard to their public health relevance, evidence on efficacy and safety, and comparative cost-effectiveness. They are intended "to be available within the context of functioning health systems at all times in adequate amounts, in the appropriate dosage forms, with assured quality and adequate information, and at a price the individual and the community can afford<a href="#_ftn1" title>[1]</a>.” (The Selection of Essential Medicines, WHO)</p> <p>In 1975 the World Health Assembly requested WHO to create a guidance tool that would help member states in selecting and procuring quality-assured essential medicines. The first WHO Model List of Essential Medicines list (WHO EML) was published two years later, establishing a guiding principle that some medicines were more useful than others and that these medicines were often not available to all who needed them.<a href="#_ftn2" title>[2]</a> Selection of these medicines was initially opinion-based, relying on a physician’s experience in treating patients; now the list is based on an approach grounded in scientific evidence.</p> <p>In 2015, UICC convened experts to review the cancer medicines listed on the WHO EML. As a result, the methodology for the selection of essential cancer medicines was revised to propose medicines based on specific regimens for specific cancers, which would make it easier for policymakers to identify cancer medicines relevant for their national disease burden.<a href="#_ftn3" title>[3]</a> Using this process, the WHO EML was further updated, with the addition of cancer medicines in 2017 and 2019. In the EML review for 2021, more than a quarter of applications were for cancer medicines, showing the pressing need for cancer medicines to be available for populations globally in light of the rising burden of cancer.</p></div> </div> </qz-section> </div> </div> <div> <a class="on-page-anchor" id="49453"></a> </div> <div> <div> <qz-section spacing="bottom-small top-none"> <div class="text"> <div><h2><span class="text-orange">Improving access to essential cancer medicines</span></h2> <article class="media--view-mode-ckeditor--full align-center media--view-mode-ckeditor"> <img loading="lazy" width="480" height="255" src="data:image/webp;base64,UklGRkYAAABXRUJQVlA4IDoAAACQAQCdASoKAAUAAUAmJZwAAn7tMyAA/v7LzOd8ey1V5r6+vfhCOfz+GPjvmJD8xv62sgy9CwokgAAA" alt="Differences between NEMLs and WHO EML map" title="Differences between NEMLs and WHO EML" class="lazyload" data-src="/sites/default/files/styles/original_small/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=Qntnc8ND" data-srcset="/sites/default/files/styles/original_placeholder/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=RKH4PTo9 10w, /sites/default/files/styles/original_small/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=Qntnc8ND 480w, /sites/default/files/styles/original_medium/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=k3we1Nk4 768w, /sites/default/files/styles/original_large/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=cWjfQYqb 1024w, /sites/default/files/styles/original_extra_large/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=opz-tLxF 1440w, /sites/default/files/styles/original_full/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=Y3fTzOZu 1920w, /sites/default/files/styles/original_4k/public/thumbnails/image/Differences%20between%20NEMLs%20and%20WHO%20EML_0.jpg.webp?itok=Vgmu-mEo 3019w" data-sizes="auto"> </article> <div class="dnd-caption-wrapper"> <p><em>Source: Bull World Health Organ 2019;97:394-404C doi: <a href="http://dx.doi.org/10.2471/BLT.18.222448">http://dx.doi.org/10.2471/BLT.18.222448</a></em></p> </div> <p>It is particularly important that these essential medicines are available for cancer patients in a timely manner, as the likelihood of a better outcome and quality of life increases when the cancer is detected and treated early.</p> <p>Yet, many countries – particularly in low-resource settings – struggle with numerous barriers to access. These barriers include the pricing and quality of medicines, procurement and supply chain issues, diagnostic capacity, infrastructure and the lack of adequate human resources.</p> <p>As of 2019, comprehensive cancer services were only reported to exist in fewer than 15% of low- and middle-income countries, against 90% of high-income countries. Less than 50% of cancer medicines on the WHO EML are still not available to patients living in LMICs and more than 80% of the world’s population <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301382/">has little or no access to pain medicines</a>, such as morphine and other opioids.</p> <article class="media--view-mode-ckeditor--full align-center media--view-mode-ckeditor"> <img loading="lazy" width="480" height="320" src="data:image/webp;base64,UklGRmAAAABXRUJQVlA4IFQAAADwAQCdASoKAAcAAUAmJZwCw7YtzbPc+/AA/vhGVv8Bfmz0RP5v1RNG/Vlil0/GHC8sPfVIxwMs3ReDdXzh37CTI199kppBm6bk26A9HY0a+QL0gAA=" alt="Distributed opioid morphine-equivalent map" title="Distributed opioid morphine-equivalent " class="lazyload" data-src="/sites/default/files/styles/original_small/public/thumbnails/image/Figure-Distributed-opioid-morphine-equivalent-morphine-in-mg-patient-in-need-of_0.png.webp?itok=KUhtBPLf" data-srcset="/sites/default/files/styles/original_placeholder/public/thumbnails/image/Figure-Distributed-opioid-morphine-equivalent-morphine-in-mg-patient-in-need-of_0.png.webp?itok=xy8TVTa- 10w, /sites/default/files/styles/original_small/public/thumbnails/image/Figure-Distributed-opioid-morphine-equivalent-morphine-in-mg-patient-in-need-of_0.png.webp?itok=KUhtBPLf 480w, /sites/default/files/styles/original_medium/public/thumbnails/image/Figure-Distributed-opioid-morphine-equivalent-morphine-in-mg-patient-in-need-of_0.png.webp?itok=hJDsDmHL 768w, /sites/default/files/styles/original_large/public/thumbnails/image/Figure-Distributed-opioid-morphine-equivalent-morphine-in-mg-patient-in-need-of_0.png.webp?itok=vvh4itKa 850w" data-sizes="auto"> </article> <div class="dnd-caption-wrapper"> <p><em><strong>Distributed opioid morphine-equivalent (morphine in mg/patient in need of palliative care, average 2010–13), and estimated percentage of need that is met for the health conditions most associated with serious health-related suffering</strong></em> <br> <em><a href="https://www.researchgate.net/figure/Figure-Distributed-opioid-morphine-equivalent-morphine-in-mg-patient-in-need-of_fig1_323496016/download"><u>Source</u></a>: Knaul FM, Farmer PE, Krakauer El, et al (2017).</em> </p> </div> <p> </p> <p>The incredible progress made in making other medicines more accessible, such as antiviral medicines for <a href="https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(17)30052-8/fulltext">HIV/AIDS</a> and antiviral medicines for <a href="https://www.who.int/news/item/27-01-2021-who-highlights-progress-in-accelerating-access-to-hepatitis-c-diagnostics-and-treatment-in-low-and-middle-income-countries">hepatitis C</a>, shows that this situation can be changed. To do so requires strong government commitment, and a multi-stakeholder approach to strengthen health systems and build effective and sustainable procurement and supply chain processes to improve the delivery of cancer medicines so the appropriate treatment reaches the right patients at the right time.</p> <p>Establishing a comprehensive National List of Essential Medicines (NEML) tailored to the needs of the population is a key first step for a country to improve the accessibility and availability of cancer medicines. Currently, there is a notable discrepancy in many countries between their NEML and the WHO EML: many essential cancer medicines, are simply not included on the NEMLs.</p> <p>Another crucial step is to support countries in developing sustainable health financing and the capacity for the appropriate diagnosis of cancer, as well as the proper handling and supply monitoring of cancer medicines. In this regard, it is essential to address regulatory capacity, procurement, forecasting and supply chain management.</p> <p>Addressing the issue of affordability is another issue that needs to be addressed, including for those medicines still on patent. Various approaches can come into play here including the use of public-health oriented voluntary licences for essential medicines and by supporting manufacturers of generic and biosimilar medicines in developing, registering and supplying quality-assured medicines at affordable prices.</p></div> </div> </qz-section> </div> </div> <div> <a class="on-page-anchor" id="49455"></a> </div> <div> <div> <qz-section theme="none" spacing="bottom-none top-none"> <qz-two-column ratio="7_5"> <div slot="col1"> <div> <div> <div> <qz-section spacing="bottom-small top-large" content-padding="none"> <div class="text"> <div><div class="dnd-caption-wrapper"> <h2><span class="text-orange">National Lists of Essential Medicines (NEML)</span></h2> </div> <p>The selection of essential medicines is one of the core components of a national medicines policy. The WHO EML serves as a model to help countries prioritise what is included in their NEMLs for public procurement.</p> <p>The selection of essential medicines is one of the core components of a national medicines policy. The WHO EML serves as a model to help countries prioritise what is included in their NEMLs for public procurement.</p> <p>A NEML can decrease barriers to access by maintaining focus on a limited list of medicines. However, lists are not always updated in a timely manner. An analysis of 135 NEMLs in 2016, found that of the 25 cancer medicines on the 2013 WHO EML and 16 added in 2015, a median of 17 and 3 appeared in NEMLs respectively.<a href="#_ftn4" title>[4]</a></p> <p>The addition of a medicine on the NEML is a crucial step towards ensuring its availability. These lists should be updated at regular intervals.</p> <p><span class="text-size-lg"><span class="text-navy">View the step by step process countries can use in revising their NEMLs. →</span></span></p></div> </div> </qz-section> </div> </div> </div> </div> <div slot="col2"> <div> <div> <div> <qz-section spacing="bottom-small top-none" content-padding="none"> <div class="text"> <div><figure role="group" class="media--view-mode-ckeditor--full"> <article class="media--view-mode-ckeditor"> <img loading="lazy" width="480" height="1242" src="data:image/webp;base64,UklGRvIAAABXRUJQVlA4IOYAAABwBQCdASoKABoAPm0qkUWkIqGYBABABsSzgE6P4JgAjUpsjNQD9Nxk0NwxqyPzr/Lc1QFAAP7+BXNMZ0Y/sC606uglGlfv1fs58u/ulr2vlIoaKkZzQUq/P8k14cW+rj0W0lX52ZP2Xyerw9jYp+Wl2u/jk8gafu8xh144GoOmiUiGvmmK2zN7IraPrR2EHo0POdf9HXpj8z7Ws+43Y/RMf0hM/iihKdv6cbNPW/f1b8QC05X+3TmObo9sv7OpF37L+0keRyEXjf4ExzRqY7B9VZrdc2ovspY9MKC3t3uEuN7aoqAAAA==" alt="Infographic showing 7 step process for updating NEMLs" class="lazyload" data-src="/sites/default/files/styles/original_small/public/2023-09/7-steps-process-of-updating-nemls-2023-icons-v2.png.webp?itok=INkSA5K9" data-srcset="/sites/default/files/styles/original_placeholder/public/2023-09/7-steps-process-of-updating-nemls-2023-icons-v2.png.webp?itok=Y96QtCo_ 10w, /sites/default/files/styles/original_small/public/2023-09/7-steps-process-of-updating-nemls-2023-icons-v2.png.webp?itok=INkSA5K9 480w, /sites/default/files/styles/original_medium/public/2023-09/7-steps-process-of-updating-nemls-2023-icons-v2.png.webp?itok=szd9-e24 768w, /sites/default/files/styles/original_large/public/2023-09/7-steps-process-of-updating-nemls-2023-icons-v2.png.webp?itok=C9oRbsIm 850w" data-sizes="auto"> </article> <figcaption><em><strong>Source:</strong> Rashid , Shafia. “Updating National Essential Medicine Lists: A Step-by-Step Advocacy Guide .” World Health Organization, World Health Organization, Aug. 2016, <strong><a href="http://apps.who.int/medicinedocs/en/m/abstract/Js23536en/">apps.who.int/medicinedocs/en/m/abstract/Js23536en/</a></strong>.</em></figcaption> </figure> <p class="text-align-center"><a class="link-button--primary" href="/sites/default/files/2023-09/7-Steps-process-of-updating-NEMLs-2023-icons-v2.pdf">Download the infographic</a></p> <p class="text-align-center"> </p></div> </div> </qz-section> </div> </div> </div> </div> </qz-two-column> </qz-section> </div> </div> <div> <a class="on-page-anchor" id="49456"></a> </div> <div> <div> <qz-section spacing="bottom-small top-small"> <div class="text"> <div><h2><span class="text-orange">The role of UICC and its members</span></h2> <p>Establishing a NEML is crucial; however, additional steps must be taken <a href="/node/25422">to overcome barriers</a> and ensure access to medicines. </p> <p>These challenges are increasingly being raised in discussions between policymakers, civil society and the pharmaceutical industry, as governments move towards Universal Health Coverage.</p> <p>Building on this momentum, <a href="/sites/main/files/atoms/files/WCLS2019_PPD%20Report_A4_FA.pdf">UICC was instrumental in bringing the cancer community together</a> for an open, inclusive, constructive, and evidence-based dialogue about how to pursue solutions collectively to improve access to cancer medicines, for the wellbeing of patients and sustainability of cancer care and health systems.</p> <p>Members can pursue this issue and encourage governments and policymakers to ensure the implementation of an evidence-based NEML, in alignment with the WHO Model List of Essential Medicines, as a first step in improving access to cancer medicines.</p></div> </div> </qz-section> </div> </div> <div> <div> <qz-section theme="dark_blue" spacing="bottom-small top-small"> <div class="text"> <div><article class="media--view-mode-ckeditor--quarter align-left media--view-mode-ckeditor"> <img loading="lazy" width="480" height="528" src="data:image/webp;base64,UklGRuoAAABXRUJQVlA4WAoAAAAQAAAACQAACgAAQUxQSGEAAAABcFtr25q8Vdy9SuWpjNKdijlSsQQjMIFLxSBUOgCHmgFS4bBCREwA/gxKX+LiXv1A7O/3XHsb3e+L8wYAUdwv+f3uAdje6s51xwCIUq8ZEDYgTdoDaTzsA5pgU2XD0vArAFZQOCBiAAAAMAIAnQEqCgALAAFAJiWwAnQwQAFH2uOkkAAA/volkH8q7ST+kj0Ow/tam13Dxg7wf9jSC1e2fzZNX/zvkEf4dnUOk1H5/Bf8lG5/4OTP8Vu/+DJtbnPFJ3pUSWFUxUAAAAA=" alt="ATOM logo byline" title="ATOM logo byline" class="lazyload" data-src="/sites/default/files/styles/original_small/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=iQ3R39Wz" data-srcset="/sites/default/files/styles/original_placeholder/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=xHSeFZ4o 10w, /sites/default/files/styles/original_small/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=iQ3R39Wz 480w, /sites/default/files/styles/original_medium/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=MHlxfy8f 768w, /sites/default/files/styles/original_large/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=ZlxXgJie 1024w, /sites/default/files/styles/original_extra_large/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=RgqhFrtt 1440w, /sites/default/files/styles/original_full/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=8Ms_B7sJ 1920w, /sites/default/files/styles/original_4k/public/thumbnails/image/ATOM_BM_Full%20colour_RGB_Stack%20Rev.png.webp?itok=QqkgiqEC 2480w" data-sizes="auto"> </article> <h3><span class="text-orange">The ATOM Coalition: Strengthening access to essential oncology medicines in low- and lower-middle income countries  </span></h3> <p>Launched in May 2022, the <a href="http://www.uicc.org/ATOMCoalition">Access to Oncology Medicines (ATOM) Coalition</a> is a global partnership led by the Union for International Cancer Control (UICC). The Coalition of more than 40 leading organisations from civil society, and the public and private sectors, works collectively to address the access barriers to essential cancer medicines in low- and lower middle-income countries (LLMICs). </p> <h4><span class="text-navy">Increasing access to WHO EML cancer medicines  </span></h4> <p>The ATOM Coalition’s Medicines Expert Advisory Group was established to identify and prioritise the essential cancer medicines that the ATOM Coalition will initially focus on. </p> <p>An international team of experts leads the Advisory Group, including members of the <a href="https://www.who.int/our-work/access-to-medicines-and-health-products/controlled-substances/work-on-controlled-medicines/expert-committee-on-selection-and-use-of-essential-medicines">WHO Expert Committee on Selection and Use of Essential Medicines,</a> members from the Medicines Patent Pool Advisory Committee, as well as representatives from Access to Medicine Foundation and the American Society for Clinical Pathology. A key recommendation by the group, which has been adopted by the ATOM Coalition, is to prioritise medicines listed on the WHO Model List of Essential Medicine that target those cancers causing the heaviest mortality in LLMICs: lung, colorectal, breast, cervical, prostate and childhood cancers.   </p> <p>The priority list consists of two parts. The first is a list of patented medicines for cancer currently listed on the WHO EML or likely to be included in future revisions. The expert advisory group provides guidance to the Coalition on which medicines from this list to pursue voluntary licenses facilitated by Medicines Patented Pool.   </p> <p>Additionally, the Advisory Group has developed a second priority list of approximately 17 generic and biosimilar medicines to focus on, with an initial focus on breast cancer, before expanding focus to other high-priority cancers mentioned above. The Access to Medicine Foundation’s new industry programme on generic manufacturers and their work on a product list for cancer medicines helped to inform this second list.  </p> <p>In its first phase, the ATOM Coalition will focus its efforts on improving access to these prioritised medicines in the 46 countries targeted by the ATOM Coalition. In the coming year, the list is expected to expand to cover more medicines and cancers. </p> <p><a class="link-button--secondary" href="/ATOMCoalition">Find out more about the ATOM Coalition</a></p></div> </div> </qz-section> </div> </div> <div> <div> <qz-section color="orange" spacing="bottom-none top-small"> <strong class="text-left"></strong> <h2 class="text-left"> <a name="-related-pages">Related pages</a> </h2> <i class="text-left"></i> </qz-section> </div> </div> <div> <div> <qz-section spacing="bottom-small top-none"> <div> <qz-grid cols="3" justify="center"> <qz-card label="ATOM Coalition Home " has-action has-more variant="full-image" card-link="/atom/atom-coalition-home"> <div slot="media"> <div> <img loading="lazy" src="/sites/default/files/styles/portrait_placeholder/public/2023-06/shutterstock_1033448467.jpeg.webp?itok=p7TaX3Bn" width="480" height="640" alt="ATOM Coalition: Medicines being dispensed to patient" class="lazyload" data-src="/sites/default/files/styles/portrait_small/public/2023-06/shutterstock_1033448467.jpeg.webp?itok=GD3i6pHi" /> </div> </div> <div><p>The Access to Oncology Medicines (ATOM) Coalition ambition's is "to reduce suffering and deaths caused by cancer in low- and lower-middle income countries through improved access to and use of essential cancer medicines".</p></div> <qz-link slot="read-more" href="/atom/atom-coalition-home"> <qz-icon color="white" class="p-4" name="arrow-right"></qz-icon> </qz-link> </qz-card> </qz-grid> </div> </qz-section> </div> </div> <div> <div> <qz-section theme="dark_blue" spacing="bottom-small top-small"> <div class="text"> <div><h3>Useful links for further reading</h3> <ul> <li><a href="https://www.who.int/medicines/publications/essentialmedicines/en/">WHO EML 2019</a></li> <li><a href="https://www.who.int/medicines/publications/essentialmedicines/en/">EMLc 2019</a></li> <li><a href="https://www.who.int/medicines/en/">WHO Essential Medicines and Health Products</a></li> <li><a href="https://global.essentialmeds.org/dashboard/countries">The list of national essential medicine lists by countries: EMLs Around The World (essentialmeds.org)</a> </li> <li><a href="https://www.who.int/news-room/q-a-detail/medicines-fair-pricing-forum">WHO Fair pricing forum:<strong> </strong>Medicines: Fair pricing forum (who.int)</a></li> <li><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31209-6/fulltext">Essential medicines for universal health coverage</a></li> </ul></div> </div> </qz-section> </div> </div> <div> <div> <qz-section spacing="bottom-none top-small"> <div class="text"> <div><div class="boxout default box-alignment--default box-color--default box-width--default"> <h3 class="boxout-header"><span class="text-navy">References</span></h3> <div class="boxout-body"> <ul> <li><a href="#_ftnref1" title>[1]</a> <a href="https://www.who.int/medicines/areas/access/NPrices_Glossary.pdf">http://www.who.int/medicines/areas/access/NPrices_Glossary.pdf</a></li> <li><a href="#_ftnref2" title>[2]</a> 25 years of the WHO essential medicines lists: progress and challenges <a href="https://apps.who.int/medicinedocs/documents/s17543en/s17543en.pdf">https://apps.who.int/medicinedocs/documents/s17543en/s17543en.pdf</a></li> <li><a href="#_ftnref3" title>[3]</a> Shulman LN, Wagner CM, Barr R, et al. Proposing essential medicines to treat cancer: methodologies, processes, and outcomes. J Clin Oncol. 2016; 34:69–75.</li> <li><a href="#_ftnref4" title>[4]</a> Robertson J, Barr R, Shulman LN, Forte GB, Magrini N. Essential medicines for cancer: WHO recommendations and national priorities. Bulletin World Health Organization. 2016;94:735–742.</li> </ul> </div> </div></div> </div> </qz-section> </div> </div> </div> </div> <qz-section > <div class="mt-5 py-4 px-11 bg-gray-smoke grid grid-cols-4 lg:grid-cols-11"> <span class="col-span-1 text-theme-focus uppercase text-xs font-semibold tracking-widest leading-7">Tags</span> <span class="col-span-3 lg:col-span-10 col-start-2"> <span class="pr-8 lg:pr-12 font-medium text-theme-brand text-sm"> <a href="/search?field_tags=%5B%22Essential%20Medicines%20List%20%28EML%29%22%5D" hreflang="en">Essential Medicines List (EML)</a> </span> <span class="pr-8 lg:pr-12 font-medium text-theme-brand text-sm"> <a href="/search?field_tags=%5B%22Access%20to%20Medicines%22%5D" hreflang="en">Access to Medicines</a> </span> </span> </div> <div class="flex justify-between flex-col lg:flex-row pb-16 lg:pb-24 pt-8 mt-8 border-t border-gray-smoke"> <span> <p class="font-semibold text-theme-focus text-xs uppercase mb-5 tracking-widest">Last update</p> 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