Malignant Melanoma | British Journal of Dermatology

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class="widget-layout widget-layout--vert "> <div class="widget-columns widget-col-1"> <div class="col"> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.16110" aria-hidden="true"></span> <span class="toc-heading-article-flag">Editorials</span> <a class="journal-link" href="/bjd/article/178/1/12/6668319?searchresult=1"> <div class="widget-dynamic-journal-title"> Progress in the diagnosis and therapy of melanoma </div> </a> <div class="widget-dynamic-journal-authors"> T. Wiesner and A. Zbyszewski </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> These worldwide efforts to improve melanoma therapy and to identify individuals with an increased melanoma risk have already contributed to improved overall survival in patients with melanoma. However, there is still much to be done, and future efforts should be directed to all aspects of melanoma ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.16111" aria-hidden="true"></span> <span class="toc-heading-article-flag">Editorials</span> <a class="journal-link" href="/bjd/article/178/1/15/6668326?searchresult=1"> <div class="widget-dynamic-journal-title"> Sunscreen and melanoma prevention: evidence and expectations </div> </a> <div class="widget-dynamic-journal-authors"> M.R. Wehner </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> Linked Article: Olsen et al. Br J Dermatol 2018; 178 :140–147 . </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14652" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/175/5/937/6697155?searchresult=1"> <div class="widget-dynamic-journal-title"> Differences in telomere length between sporadic and familial cutaneous melanoma </div> </a> <div class="widget-dynamic-journal-authors"> C. Menin and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/5/10.1111_bjd.14652/2/bjd14652-fig-0001.jpeg?Expires=1735462074&Signature=qdlHcKjh1bQM~GAZuAShlR1jd9wTAMhZ8jg1PD6QmT~bkj9J-ApSfQr2NvH-3qrIlXW44gW~AexBwFgWD5ZyKthaPPKjBN4pRF2cSZFCogIPBiNKKXj9feNQPoEQ55offxqprUEksE1wa4Z1yIWvSMeAfdn6SOspXNlt~AUGX09k3geZbpFniUqqTo3zW5NLvszw--u8qaNFqxTa77ChZoBEtWmNB4WNp8nxbJyoSc75K5QMD-vLwwAXpKK0ywecMxvKN9158HdOKZXBZWOc5eNpP-21PgQ~CaKDkPK4cMJcmybNw7ZaJKAjssBlz4EZw49vHXra~Qbf4AfiPPQtFQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Several pieces of evidence indicate that a complex relationship exists between constitutional telomere length (TL) and the risk of cutaneous melanoma. Although the general perception is that longer telomeres increase melanoma risk, some studies do not support this association. We ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14727" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/175/5/966/6697136?searchresult=1"> <div class="widget-dynamic-journal-title"> An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel </div> </a> <div class="widget-dynamic-journal-authors"> S. Thurneysen and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/5/10.1111_bjd.14727/2/bjd14727-fig-0001.jpeg?Expires=1735462074&Signature=hu4CRElWHRzE8oYUdtnOsGzrJFNYO2phQz65urxdBBMewn~MhAdJq-OpgSKzEjOVt47JtWHdvHFNiEbUtuUHNglHb3fouviQoNX2rV-D4~gKBAYuvGQdNJZsk8FgglVG-W7gIsyqJWQPWibil56u8HXmda650rzG4avMV4~SwsfIbYx1rLsToKdn1Q~YdEdN-3TelyOPg6IrByuid7x75N6pKfHb3sClnvWC1p7BXKAN3aliVTrXUHPviyMz3zSHYNO~81Fr5UOSENlC8XZMhZGKVfqWiaLyEM3XvED-T13ip1A-32BRF5Uo5kYduI41AYJ-w7brGpgu08tKcSKwlQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background There is a medical need for new drugs in patients with BRAF wild‐type metastatic melanoma. Pazopanib is a multitarget tyrosine kinase inhibitor with antitumour and antiangiogenic activity. Objectives The primary aim was to investigate the metabolic response to pazopanib monotherapy and ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14713" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/175/6/1221/6698434?searchresult=1"> <div class="widget-dynamic-journal-title"> Dual c‐Jun <em>N</em>‐terminal kinase–cyclin D1 and extracellular signal‐related kinase–c‐Jun disjunction in human melanoma </div> </a> <div class="widget-dynamic-journal-authors"> G. Pathria and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/6/10.1111_bjd.14713/2/bjd14713-fig-0001.jpeg?Expires=1735462074&Signature=rpVUiTmE8KexUg4SaWidJp4w3P9ic1YHllDXCg5Iz5LsizOfGK2UTuI20f7qj2i8Sz3Vfw14z0TyWHksnsS3hjeEz-p5CSzky1ZPm5l54pNPAwhfhOuUnZt8Exj97jfvD4GyijkdBQoWxQEQYrDi~pvqdLt8JRGqmEFqGuwWbvh3NVBmxR0hbh1axUTelN4JQS14FB~IS6y1EYkIT-zG5WJUvW~WxyULl~Y~c5CPsfMtEch3kL-Q-WN4PHAFYQfKJV8b-q1fTlCdZIwUSmw5W3oNGO8q7OED6YiDrSgdQjmpsORXuofQM6kDDPGpE9lUa7wLiNsTwgGv8jvtLIzsOA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Activity of both c‐Jun and cyclin D1 is deemed critical for melanoma cell proliferation. This functionality is corroborated by frequently elevated expression and activity of these proteins in human melanomas. Correspondingly, alleviating c‐Jun and cyclin D1 function is vital to the ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14720" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/175/6/1210/6698456?searchresult=1"> <div class="widget-dynamic-journal-title"> The prognostic significance and impact of the CXCR4–CXCR7–CXCL12 axis in primary cutaneous melanoma </div> </a> <div class="widget-dynamic-journal-authors"> A.T. McConnell and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/6/10.1111_bjd.14720/2/bjd14720-fig-0001.jpeg?Expires=1735462074&Signature=wsa5Fg3VIL9Xap77UAqPHv2X-gpXV58EJqCqNREiA8GxSXbwSyGpdwey9xH1nUEA4kap-laCnm6p4uw2imNj3ZCInsA-WEyDMlZ0WDDU4q~7aej9aubEvEmhVxtHmuH1ks5Q03DXiLpTqXD7oK9MuFSP1solrggk8tweAOj~lPoyN~X7Yuo1dfdYVB8jl9N-oB90QlPbTd3sxGaUwMRMnh~~VfEKrfezZjwmDCrx61fZvT70tf1311D5pv5U1oVIkkxijay7HqGgpgEhr8mOJC0E9oDYHG28yQArFAsKoUlzW3rGMC0PpiB56Pbc8f9fYQUX8bgJkQbQ6G-U-JtfGg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Expression of the chemokine receptor CXCR4 is known to regulate melanoma metastasis to distant sites with high expression of the CXCL12 ligand. However, the prognostic impact of CXCR4 expression and potential for autocrine‐mediated activation of prosurvival mitogen‐activated protein ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14758" aria-hidden="true"></span> <span class="toc-heading-article-flag">EPIDEMIOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/175/5/912/6697112?searchresult=1"> <div class="widget-dynamic-journal-title"> Effects of the German skin cancer screening programme on melanoma incidence and indicators of disease severity </div> </a> <div class="widget-dynamic-journal-authors"> F. Trautmann and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/5/10.1111_bjd.14758/2/bjd14758-fig-0001.jpeg?Expires=1735462074&Signature=KVusVcv9PN~BTLkD-A9ZhnREjFdx8AqMySVFZh-kdzb1-p1OXFXoAsmeqVI3ULj-BQTSol4uDiv6p~hFHedauQT4F730GIYrr4pVe~brcKE8hyrlW646BTSTxUiZsCnlZsXYttbN7j60eHTzCK56VC664IKo~YycByT0IsEg9Y9ItJpo~MufdSHlNVAiNifbnjztyCzDK~2~vCAa6z2duJzqGnAT-20TGCwRg6Ldo1ZdsT3-L0yfYRHemFArVyGXidKp8EbJdNyPEiEhbV5zRD~wN1sS40Jq3dyLx31bAs7cR~-BbSnWCSGV5RpqS1hAOR-~OHMT7yi7oEcxTq3jgA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background In Germany a nationwide melanoma screening programme for adults aged ≥ 35 years was introduced in July 2008. Evidence on utilization and effects is limited. Objectives To examine the uptake and effects of the German nationwide screening programme. Methods This analysis is based on ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14407" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/174/6/1308/6617082?searchresult=1"> <div class="widget-dynamic-journal-title"> Characterization of patients at high risk of melanoma in Austria </div> </a> <div class="widget-dynamic-journal-authors"> C. Müller and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> Background Risk of melanoma is determined by genetic and exogenous factors. Only a few studies have included both characteristics in a comprehensive multivariable analysis. Objectives To find determinants of patients at high risk of melanoma in Austria, including phenotype, genotype and lifestyle ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14347" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/174/4/823/6617909?searchresult=1"> <div class="widget-dynamic-journal-title"> Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known <em>BRAF</em> mutation status </div> </a> <div class="widget-dynamic-journal-authors"> A.L. Frauchiger and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/174/4/10.1111_bjd.14347/2/bjd14347-fig-0001.jpeg?Expires=1735462074&Signature=g7iw-7HQ9FYYYs13s0a6Y6fqNLra3QHT7ERcZE6K03wXcAzNgHlff2oebM-Y3lP9XnjKR8R5zgvHMl1a3xwlxqOoVZa6mHugQtcl1wPGcImcJ9Xnk57KxmFB2Y-yKY6F98pm5FKPm1HaHPGDjbBN11K7uedYoRU4cu-7tSyC~l3dfzVPYdPY50TrLsaRzwlk6ACyr7Jd8JMwx2ELmjaq4vH1~C1jSmxTv1yMSE6deotre~wa~cAzHzcyWxIhDX7jEjIhnVrzKMjggPDiJC9SBeR-B-hmaKJmd5-rrSQD~ynnta8THRnsBr3c854seNMOI6ctNoBtJGHDnX5aclsPGQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Activating mutations of BRAF provide an important treatment target in patients with melanoma. The prognostic role of several biochemical markers in relation to mutation status is not clear. Objectives To analyse the prognostic significance of BRAF mutation in patients with melanoma and ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14152" aria-hidden="true"></span> <span class="toc-heading-article-flag">MEDICAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/6/1462/6616453?searchresult=1"> <div class="widget-dynamic-journal-title"> A cost‐effectiveness analysis of trametinib plus dabrafenib as first‐line therapy for metastatic BRAF V600‐mutated melanoma in the Swiss setting </div> </a> <div class="widget-dynamic-journal-authors"> K. Matter‐Walstra and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/6/10.1111_bjd.14152/3/bjd14152-fig-0001.jpeg?Expires=1735462074&Signature=tW4McHCYY6QgNw6D21rLRne-z44cSUsM8PxVgArVmkZJIuTB-VL8oBiahnWByxBOyKZ9WsVKhVyAnAS1WxPx-d5h15tAQ1vQw-YV-ITRY5UJ95tVVG04mpaVR5jL3Cfrr9tUdHnqxw0~6b29uDIA8xXQDaI19cM2ZSSdXY7oCEK6V6w9zoI3yxQUMpdQSEI9tmRWMXZQnfOsme78ME5TTKJnfOSHl8iFrDyUl0fbGeOwmHTVSAzwLRSVqaJUqxV7bkZL0SmgogqwlnWC-z~fdAOH-cftMGdVzNqfu6ZXkJ8iP1CkTtI-lvXienrKxnsZQI~9UjnQAgmigSUxsme1mA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background The treatment of patients with metastatic melanomas that harbour BRAF V600E or V600K mutations with trametinib plus dabrafenib appears to be superior to treatment with vemurafenib alone. This treatment regimen is likely to become available in Switzerland in the near future. Objectives To ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14216" aria-hidden="true"></span> <span class="toc-heading-article-flag">EPIDEMIOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/174/2/312/6616611?searchresult=1"> <div class="widget-dynamic-journal-title"> Prediction of high naevus count in a healthy U.K. population to estimate melanoma risk </div> </a> <div class="widget-dynamic-journal-authors"> S. Ribero and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/174/2/10.1111_bjd.14216/3/bjd14216-fig-0001.jpeg?Expires=1735462074&Signature=vkBoCI99BBOs~NIwFxN5VUlkBgA368TGDZemwd1tihUDrVEUiawTNzAopD~~F2Zp-S1nbQPT7jx~gpj00XGFdQ-6rY5gtGQ-R3S6T7eMcwA0o4foiIFTA1VxToQ6FI0aCPTADspyqfNMFDNyA26zhEsQ15EDBo1Rkei25zqBqHvjF02egcy6XuT~yc1Wl10xMn7bkFBUz1uPJmEVgmdA8PfUK58PNv619y~4h7Kp4e8KvNoCKAI8BjPjJefDay2APP1MWor50mDqN6TXY5~IzmJe4HbMY77md5G4cXUbpwI~nQd9d-C5hpAOO-q3hgQh3Hq0FBbywj2NR4Wa6BuG~w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Despite recent discoveries of germline and somatic mutations in melanoma, naevus count remains the most important risk factor for melanoma. Counting naevi on the whole body is time consuming. In order to identify patients at risk for melanoma, many studies have used naevus count on ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14155" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/174/1/146/6616612?searchresult=1"> <div class="widget-dynamic-journal-title"> High neutrophil to lymphocyte ratio measured before starting ipilimumab treatment is associated with reduced overall survival in patients with melanoma </div> </a> <div class="widget-dynamic-journal-authors"> J. Zaragoza and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/174/1/10.1111_bjd.14155/3/bjd14155-fig-0001.jpeg?Expires=1735462074&Signature=Z7LuZYdMxsvaLl9tjycnF2BI68ecU0wVzr5he6uQ3ONyyIvOgiIM-bbtsqBPrZOQOlknwEVbif9F8fnvPWrquzdIw8jHBPW3jduCyTAvDAOuBE~P8KBlbKcqWaAkblMAsNow~R~MJ-kXopuULM-pq5cG8A9XHEufjElpfJr9D6y7LCz6Cp7EfNe6La4vX7Zr~~L01irdSULaEieUEem3KXYzSjpXl~HUial8G3KYDGvGjxr7NCdP1OBeSZeYINpkurax1~eXfG0P~HHqq7Cf8Y5mwdT4-sL4t1YRUCnWL~fZFfzZFoF7fq5kdU~MNfBet6rNpncmB1f1e4mtpDTvVg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background There is an unmet need to identify markers predictive of response to ipilimumab in patients with melanoma because the number of responders to ipilimumab is low and its cost is very high. An increase in absolute lymphocyte count (ALC) or low neutrophil/lymphocyte ratio (NLR) just before ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13524" aria-hidden="true"></span> <span class="toc-heading-article-flag">Clinical and laboratory investigations</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/172/4/961/6616009?searchresult=1"> <div class="widget-dynamic-journal-title"> Morphological features of naevoid melanoma: results of a multicentre study of the International Dermoscopy Society </div> </a> <div class="widget-dynamic-journal-authors"> C. Longo and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/4/10.1111_bjd.13524/3/bjd13524-fig-0001.jpeg?Expires=1735462074&Signature=0BlB6kzu0iVZC7LWPszBrGNkGj6XeVfM0abLduE1wWqO~BGrIDqnFx2igtcBfJlTHi6drnYhEUYeTiPFE~3U7h-02all3f6ssLd6NxgxYLHltv2Jd1Aal~scJIZjvh4Jmh3Tt2r7yEw1kAFqEr68jxjRUWpj1Omia~xU5qubyxf9CInBent1USlc5zU1tWNnAxpFI0zjeYSSE8MbEAw6wS64WZeom4~sdYzVjBPZTqZ20ZUZg~w6TrB71b1dmQZdKEj-xoL6jcntzootE5w6D5QJcxRWxmT52b2y2i~IQkse8jW7duuTvt-4Kx-US6w5vfgpETM5Xj-YNHk3MFTn0w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Naevoid melanoma (NeM), a rare variant of melanoma, can be difficult to detect as its clinical and histopathological morphology can simulate a naevus. Objectives To describe the clinical and dermoscopic features associated with NeM. Methods Lesions with a histopathological diagnosis of ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13552" aria-hidden="true"></span> <span class="toc-heading-article-flag">Clinical and laboratory investigations</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/172/5/1269/6616066?searchresult=1"> <div class="widget-dynamic-journal-title"> Dermoscopy structures as predictors of sentinel lymph node positivity in cutaneous melanoma </div> </a> <div class="widget-dynamic-journal-authors"> T. González‐Álvarez and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/5/10.1111_bjd.13552/3/bjd13552-fig-0001.jpeg?Expires=1735462074&Signature=tAXVDzbdif8gRszhNXwNpCig9CTtVGLrjSL6UJcojnu1qCzP2ei7a6FkZxXU1Gqx-G5Nc7yMJZjYYqYGl0pr-bq3npOhdVsVW01Ivyz9gk7~4sCYUH~8dMAYYEBogmIY5pbf6vHt290pdsNBITYsj8c6yrEEAvDI~zYgjiMMhCBrD4Wb9wwedc-K9j5sLF9Um9SWj2JHnLutuOHerNymDgeWg1RLbYb6g6VuEUpk2c8KOMuyu~fkUQZUnAvuVrpBmAqo0pKNO-pDEBDiO4Vqa04jsqUB-FCiG6dn7bXh3~Wn1pauNHu-wUCpvfo3liQgNsqE-mUgpwoLYhvdvKPkZw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Histological features such as Breslow thickness, ulceration and mitosis are the main criteria to guide sentinel lymph node biopsy (SLNB) in melanoma. Dermoscopy may add complementary information to these criteria. Objectives To evaluate the correlation between dermoscopy structures and ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13489" aria-hidden="true"></span> <span class="toc-heading-article-flag">Epidemiology and health services research</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/172/3/707/6615816?searchresult=1"> <div class="widget-dynamic-journal-title"> Clinical and histological features of head and neck melanoma: a population‐based study in France </div> </a> <div class="widget-dynamic-journal-authors"> F. Dabouz and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/3/10.1111_bjd.13489/3/bjd13489-fig-0001.jpeg?Expires=1735462074&Signature=ZZjpccA280pCJHwyX8srR6C2tnrj4xjh9hhVejJL2YLxbCxzsjPkvvqvEU4udWJiqaD5GvQzX2aYadDyRRNy9h87BvZtSby-VwaTkRgxNKURjqdvq7XG1SoyY8PGKvNJwEDdSuVkQ8bz9HZM6MH8pZCSELV-Y9ltSl4fxTU6Bf7Lcvt5~8i~s7OwhN04PUU5nJ2prmoJ1DnSnFaBzA7IcDzx9zoz-OfLJvvtiQKicz1kWkN1GqsUxyaJ-cjRFsZK54i77wqAvKmvqRZzXkdYKEc3XJdLv8g3bpjTg82~JwKWU0yJbh1lEDcA6aOf2QV5CNrdkCjqOD6ZFgpECt4-~Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Head and neck melanomas (HNMs) account for an increasing proportion of melanomas and have a poor prognosis. Objectives To compare the clinical and histological characteristics of HNMs with those of melanomas at other sites (MOS), and to identify pertinent clinicopathological subgroups of ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13675" aria-hidden="true"></span> <span class="toc-heading-article-flag">PUTTING PAPERS INTO PRACTICE</span> <a class="journal-link" href="/bjd/article/172/3/566/6615897?searchresult=1"> <div class="widget-dynamic-journal-title"> No survival benefit for patients with melanoma undergoing sentinel lymph node biopsy: critical appraisal of the Multicenter Selective Lymphadenectomy Trial‐I final report </div> </a> <div class="widget-dynamic-journal-authors"> M. Sladden and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/3/10.1111_bjd.13675/3/bjd13675-fig-0001.jpeg?Expires=1735462074&Signature=diyjlTmeORCrUtCEfm3rpVhgW0ddRT79TV5GdlmxakM71zAfmh~VNAhVZ~HqEKb0wIAA9UXQPL8oqmv-y0WaaTLokDZOO~v41O8-~h1zlKJbdytYt5GwAUHoGltScQkyI1SVBj9MmQRRNC2YoUv8EzfU6yinW8KY7QWUdfzs0AGDkVEQeMkYmEAeo6LuX5QPVaS0kDb~7eu1Q6PilJSdLTz-BBZqJ~fFgypBTu3oz-n9KohrN1Md~b4Llmuw76Awo-9oeFvwUXIO0DIohdhq0tV5Xh1POy2MfJLYiSYuw3SKyAVLOeSE1~k3mOFPWnSfwahjG47FvJ-ViBWWeX1Xgg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Sentinel lymph node biopsy (SLNB) was developed in the hope that it would improve outcomes for patients with melanoma. SLNB is an area of discussion and controversy in melanoma medicine. The final trial results of the Multicenter Selective Lymphadenectomy Trial (MSLT‐I) have now been ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13861" aria-hidden="true"></span> <span class="toc-heading-article-flag">Clinical and laboratory investigations</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/1/106/6616875?searchresult=1"> <div class="widget-dynamic-journal-title"> Pigmented nodular melanoma: the predictive value of dermoscopic features using multivariate analysis </div> </a> <div class="widget-dynamic-journal-authors"> M.A. Pizzichetta and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/1/10.1111_bjd.13861/3/bjd13861-fig-0001.jpeg?Expires=1735462074&Signature=PRtg84daCRW7E6GdyuoPzZ-YqM6mHVkD~beOlpJk0BcrhdcqpWN08OXv85V14b81aYEIZFbt0Ox1TOJujkAcvnS2hS7hczlbYQtGcGfUlJq9JzKlNAcmwEpnfURkMTLUnIJqFKMDkr0jktX3UUw7scsiLovWylZ4Eium4ejPeQDCSttCrcU5y6LSxWSacLqifnxkk4tUc63Efe9vBLkkOWeGyP8L7JYY-ILD7C-atz5HK1BcNx9nfQDmOyZ-xT1v-K1QuobudZKG3fnjHFE~4Aj33kZBpzoVd~lqVttRrNQyS1clnAxbrnAkYh6~SOcVqlCxz2kCMpbMePBB9akkiA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Nodular melanoma (NM), representing 10–30% of all melanomas, plays a major role in global mortality related to melanoma. Nonetheless, the literature on dermoscopy of NM is scanty. Objectives To assess odds ratios (ORs) to quantify dermoscopic features of pigmented NM vs. pigmented ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14495" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/175/4/744/6616874?searchresult=1"> <div class="widget-dynamic-journal-title"> Dermoscopy, a useful tool for general practitioners in melanoma screening: a nationwide survey </div> </a> <div class="widget-dynamic-journal-authors"> P. Chappuis and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/4/10.1111_bjd.14495/3/bjd14495-fig-0001.jpeg?Expires=1735462074&Signature=G72cgGW9ee33YDcQa-GTRKJuPQc6jI0uEczMg6td6aDbOXzKW3G2gMAQ4C0COlDL-BMrTfmFLoZIj~lH-B~oNZCXVZ9ez-YxDipuIsENEkdjxwnZP04dXAG5n1Bvv~RmTPpP3h7DPtv62RYYp38RKyv12PTUblkXntJwv6F5No05OlfjwumM-8w55P3kTyzj~agE8aDFRfNfy54ROnBP-LzADNLdBxBf-n4lEJWtR7jI6n6ZkxLjNUv86mMvuN17FbP~eaR9J2GiLSN146wfA4FOA3IJmMc1HFUMN3-u6SohVhEk5e-XpJZmovb-0tEYnxofPpYoVMP63~faLYhd9w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Dermoscopy improves diagnostic accuracy in melanoma, as shown by several meta‐analyses. Although it is used by general practitioners (GPs) in Australia, Canada and Italy, no published data on this topic are available in France. Objectives To review the opinions and use of dermoscopy by ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13403" aria-hidden="true"></span> <span class="toc-heading-article-flag">Systematic review</span> <a class="journal-link" href="/bjd/article/172/1/33/6615755?searchresult=1"> <div class="widget-dynamic-journal-title"> Clinical practice guidelines for identification, screening and follow‐up of individuals at high risk of primary cutaneous melanoma: a systematic review </div> </a> <div class="widget-dynamic-journal-authors"> C.G. Watts and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/1/10.1111_bjd.13403/3/bjd13403-fig-0001.jpeg?Expires=1735462074&Signature=S7niebNdT2qmuu2IdQQv-Stu89MEoMlm4y7jH7~KPHHAmvihQ6C8C4VnK1vtqYgjqw6qpNgnJt5euOCbD4g7vbgOIEBIwoJGDl03NG4D1n4sHhj5XvBth6Zr3ULeYRQPxKGqLW9lf6730NmWM7Zuc4fmc0PB0jOyM4~resw9gQz~bwZ1NCca8IuiqtmTe38b5wL6XYELyaKrlQFEo1vUzW2JWntCAlm80LX1Nh2rMTD4S8uqqBCpJlLn8Aip9wTz2yMZdRMUjkdwZkx7VCLVrWMaNkwHk4mY1CUZCnhnB1L5zQtCY-E2MdWQ-OBajVMSphHesDMy5yFeykeiaXS6Sg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Understanding how individuals at high‐risk of primary cutaneous melanoma are best identified, screened and followed up will help optimize melanoma prevention strategies and clinical management. We conducted a systematic review of international clinical practice guidelines and documented the quality ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13483" aria-hidden="true"></span> <span class="toc-heading-article-flag">Epidemiology and health services research</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/172/3/700/6616040?searchresult=1"> <div class="widget-dynamic-journal-title"> Trends in cutaneous malignant melanoma in Sweden 1997–2011: thinner tumours and improved survival among men </div> </a> <div class="widget-dynamic-journal-authors"> J. Lyth and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/3/10.1111_bjd.13483/3/bjd13483-fig-0001.jpeg?Expires=1735462074&Signature=rPDqgFYJes8FMe8FAiMIOnMNG3p0nueHgmmhdtQOaBn7zsLcYxxjZJ302s2-wCautqCjDXr2UfuuzSocUNIFu9b306uffhG8xEGPKXPYWrF89vW0rSevcHvvjBInJPwVCA0oh0bUeMm4UP~WMm-omZHh3cU4bFGuO5Q0VPOEX8ACPjnG6FNtoFQ-TBpW02SwvutbWQ~gGKvEJF77j6f5e8JRc9GZ3vApoM5LyXtTPwYuOreIpSa8X9BBIiQgkUtbO7qyq8qf-zZu1XjZOmp5CjhbhLcEAXi5CJ2nD-NrX4Rwn2Xe46A~L482cerPpUisomWSUfC7Ss-OaT~ZkPjSSg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Both patient survival and the proportion of patients diagnosed with thin cutaneous malignant melanoma (CMM) have been steadily rising in Sweden as in most Western countries, although the rate of improvement in survival appears to have declined in Sweden at the end of the last millennium. ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14323" aria-hidden="true"></span> <span class="toc-heading-article-flag">Original Articles</span> <span class="toc-heading-article-flag">TRANSLATIONAL RESEARCH</span> <a class="journal-link" href="/bjd/article/174/2/364/6616682?searchresult=1"> <div class="widget-dynamic-journal-title"> Impact of oncogenic BRAF mutations and p16 expression on the growth rate of early melanomas and naevi <em>in vivo</em> </div> </a> <div class="widget-dynamic-journal-authors"> P. Tschandl and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/174/2/10.1111_bjd.14323/3/bjd14323-fig-0001.jpeg?Expires=1735462074&Signature=cPdMq2HPUFKdTlpSXY6T-rpsGdYeE3WRXPSjMWGcphRXBysps~FMDFE8O1rCYdjZW8R9jBRL8lEyl1KSwgrEF0WwrL~oslasiWAKN5raEMfYgKPMqewh9N6Dlaq5x29Wxzvw58HHINAasEOhZMAVD64ibtznd2Y2i-eTTLLR4JeLiRcVMw8XKQY0ui2p1qsnh59SI5MhLw5Ef9o-qQVQwgt9ejofcXwZLaSqReJDMeIynbxPTEjn23kyZ6UGUL2pu9G2CoiuDO0vuYNp7gVr-eYXq3qS4Hf38kMNA-lt7WvdBc1AaSvBUiH~jM65OhHGjd8sqR7tOVNc3LQ6e6d~Nw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background It is important to know what drives and arrests melanocytic growth in vivo but observations linking oncogenic mutations to growth rates of melanocytic neoplasms in vivo are sparse. Objectives To clarify the relationship between BRAF V 600E mutations and p16 expression and the growth rate ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14049" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/5/1232/6616854?searchresult=1"> <div class="widget-dynamic-journal-title"> Melanoma and naevi with a globular pattern: confocal microscopy as an aid for diagnostic differentiation </div> </a> <div class="widget-dynamic-journal-authors"> E. Benati and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/5/10.1111_bjd.14049/3/bjd14049-fig-0001.jpeg?Expires=1735462074&Signature=0DdvXQQ2uABbk~Yq9JhXAXfIT1UzZ6mD43HM6Yxg2T25EhiFjKy-dViY3RUqJj4BURVkGZCZWc9y7YxSO5f5-7rnQ07SjTclJFCeHJaQhNu70ctk6bhfRS2p9-xZ0STShqxTQ5oS~WcPTk-oIp56GsVwCuG1U12lSc0nTmKxcMmWwprkE5zWnY1MIWYVNFpkeAOOto0WwlDq6x25j~YcenGbAigBAsTky1TwFTilA7PErhdWXwSPZvEojzFFzvZvwWUl26Z3aJVhCS5LWKeo6VRgN0cIATuorD0HVI23lwbA7SRF6VYBrsWwQksK48Gu6K8gyxSgCeqdAfV6TB0a2g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Dermoscopically, one of the most common findings in melanocytic lesions is a globular pattern. A regular globular pattern is a common finding in naevi. Melanoma can also show a globular pattern, with globules typically irregular in size, colour and distribution. Objectives To investigate ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13829" aria-hidden="true"></span> <span class="toc-heading-article-flag">Clinical and laboratory investigations</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/3/671/6627450?searchresult=1"> <div class="widget-dynamic-journal-title"> Mutational status of naevus‐associated melanomas </div> </a> <div class="widget-dynamic-journal-authors"> D. Shitara and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/3/10.1111_bjd.13829/2/bjd13829-fig-0001.jpeg?Expires=1735462074&Signature=gMX-E5MPvCrlIuwSAH0mUgXHh4Z8x6Jc9QCRqATroCNGL2AyqB0ZVyF5mINPDVR1XZYbheo3CxOJjjf~VS420HCEkmz3gJJe3ilT5xgM8jhlbGtR6mlicXnPoyCspuhhnmpwfDQhAbtsykWfh4YKHp7A1oB5ENpd9dEWlPrKI~ZpB884FUm7HxyQSg7qqD5OpFlk-UVKBWE5TAQAl-uzCvaQui0vR2OI~ZzwNaLiRDAECgkdiKpWeUuAw0XdGFPMXx-WFivbbkv7JTOC9Q5b76dU8nJBazu-M6JG1sQY4KZpM7rR7e5fPlvodB6dSdvJ2H-wOnILazMDkCvcckHB9w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background The origin of melanoma has always been a debated subject, as well as the role of adjacent melanocytic naevi. Epidemiological and histopathological studies point to melanomas arising either de novo or from a naevus. Objectives To evaluate the presence of mutations in genes from well‐known ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14630" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/175/6/1301/6698420?searchresult=1"> <div class="widget-dynamic-journal-title"> Consumer acceptance of patient‐performed mobile teledermoscopy for the early detection of melanoma </div> </a> <div class="widget-dynamic-journal-authors"> C. Horsham and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/6/10.1111_bjd.14630/2/bjd14630-fig-0001.jpeg?Expires=1735462074&Signature=HbhqIsnzhZ0i8-mRcMyBUp-w0w24h9Fr8D8wjWj11CB-kcQZz9LovQZ-DiY11-2f2b8kT8yxwjpsOHS77hUVGEarm4QKxUP8Sv5tlZEPjYkl~qLyOZ-RvaslUAFOPVr-~zw5eLOOZ0dJbHWkE-y9~iNfhKk~xXYFeuYmJpNmjYZVOuTs7sqbHBDgTGr8YaO7v9cO~JBWRjYIwDUDD28tfFtL6aKlFLOE0mS8lFZt1O5iKHrq1nSJoXzw18hV3DgfIsZGLOcQnJp7eD15kzQ4LpWDyavIvjHviDEA9MWgq2CXibUNDN7uCiNgJfrh3pVKkdyqmsl-n9DKxT4TpVS0EQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Mobile teledermoscopy allows consumers to send images of skin lesions to a teledermatologist for remote diagnosis. Currently, technology acceptance of mobile teledermoscopy by people at high risk of melanoma is unknown. Objectives We aimed to determine the acceptance of mobile ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.16109" aria-hidden="true"></span> <span class="toc-heading-article-flag">Editorials</span> <a class="journal-link" href="/bjd/article/178/1/9/6668353?searchresult=1"> <div class="widget-dynamic-journal-title"> Advances in the diagnosis of pigmented skin lesions </div> </a> <div class="widget-dynamic-journal-authors"> P. Tschandl and T. Wiesner </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> Dermatology is a discipline that is based mainly on visual inspection of the skin and is therefore well suited for telemedicine. With the advancements in telecommunication and smartphone technologies, telemedicine has several advantages for physicians and patients, such as reduced travel and ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.16112" aria-hidden="true"></span> <span class="toc-heading-article-flag">Editorials</span> <a class="journal-link" href="/bjd/article/178/1/5/6668391?searchresult=1"> <div class="widget-dynamic-journal-title"> How breakthroughs in translational research have impacted treatment strategies for melanoma </div> </a> <div class="widget-dynamic-journal-authors"> S. Verykiou and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> Malignant melanoma is the most aggressive form of skin cancer, and although patients have an excellent prognosis if diagnosed early, the prognosis for late‐stage metastatic disease is very poor due to the lack of effective treatments. Therefore, improved strategies are urgently required to ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14897" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/175/5/1030/6697173?searchresult=1"> <div class="widget-dynamic-journal-title"> Genetic susceptibility to cutaneous melanoma in southern Switzerland: role of <em>CDKN2A</em>,<em> MC1R</em> and <em>MITF</em> </div> </a> <div class="widget-dynamic-journal-authors"> C. Mangas and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/5/10.1111_bjd.14897/2/bjd14897-fig-0001.jpeg?Expires=1735462074&Signature=G95ivhmVfBElzWzH~r9WAopkfb3zgBPt9h8Vc0h2UYO1~ONzGYfywObkd3dxB-36ft3Fz7lfLRph5ef71xYLv8tQ8-PJBhqSqAEYg645AesZ-Mtpgzc4jKpBxctwgBJhVnKCJ5W5AwzlcPSJ3giGesBAyhwZ2V4no5re6YcqDjGxxBoty1kGee8IFiO8-4dOdggR0Rf1iPTEtMUH-Mz7ILeZ0g8Rg8uNoyzAL7wNL-36Z9NwazXv3u91iarLlZQqMFlwawmBEXNWmdJhQM7EKgmkWcyFRF-IgaeTMImBO5dk2QNo06jK8rl8tvlETJhE1QAPXK9GgdJTZCD3E99-4A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Nearly 10% of all cases of cutaneous melanoma (CM) occur in patients with a personal or family history of the disease. Objectives To obtain information about genetic predisposition to CM in Ticino, the southern region of Switzerland, a zone with moderate‐to‐high CM incidence. Methods We ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14919" aria-hidden="true"></span> <span class="toc-heading-article-flag">British Skin Foundation, Skin Deep ‐ 20 Years of Research, 20th Anniversary Conference, 13th October 2016, Royal College of Physicians, London, U.K. Publication of this supplement was supported by Stiefel, a GSK company</span> <span class="toc-heading-article-flag">Review Articles</span> <a class="journal-link" href="/bjd/article/175/S2/30/6616327?searchresult=1"> <div class="widget-dynamic-journal-title"> Vitamin D, vitamin A, the primary melanoma transcriptome and survival </div> </a> <div class="widget-dynamic-journal-authors"> S.J. O'Shea and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/S2/10.1111_bjd.14919/3/bjd14919-fig-0001.jpeg?Expires=1735462074&Signature=zAcmLkrXlUOLGyxy5-l0ymxAnPsfea9L79O4HMlJ9wFyWBpCABBwN-y8nsLHxXRPVPUr4L~mv5XF8PY5EBr0n6kjP8dx3GQAOOyYpAHxltintLwaX8FAmdUCIvPkROe8o4Fzp9~9IzrYT9XoACUVPO9Q8pOfEP853qwQ3MgPTyrDbsSE7IRLW~h~Fy~uijlpCgwJuPVxcjkpDReBNPaWD-W1CgTThtQL2tYpltwLsL1hDjPiFK32Ce8YgoYnzgJTi39tOfgOMVx3AqE~6jGRJDggd8r2LaC8fyvZP8zvDibH56OGpzMt98SBb0Bxnka14hRYlpQzHuVm~i9sn3JZJg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Survival from melanoma is influenced by several, well‐established clinical and histopathological factors, e.g. age, Breslow thickness and microscopic ulceration. We (the Section of Epidemiology and Biostatistics, University of Leeds) have carried out research to better understand the biological ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14286" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/174/3/610/6617143?searchresult=1"> <div class="widget-dynamic-journal-title"> Spitz naevi and melanomas with similar dermoscopic patterns: can confocal microscopy differentiate? </div> </a> <div class="widget-dynamic-journal-authors"> S. Guida and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/174/3/10.1111_bjd.14286/1/bjd14286-fig-0001.jpeg?Expires=1735462074&Signature=mv5dWPhAn~1-Tvefqxzj1zcXSTcPiItLt0bjpuYpvyXmrmHI4adzLTDsp7Pog8gf0LaTaTY~XZ8NP7om9F6XfUZEbrDMpuC4mm1sGSV8ihU2sVr47n4ccV8n3qATIFn3n2rk7zyJtILUQQb0ETRSjnNBuU0Q6jWf2ZEUisHw9uuAJUODpWWKCdfVFpiEYHRlJQPPAF2QAUTGs-fvTXjVJKFSpEFdQkvbu5NOUS~2ndg4c11nvJq0YgGyhp--FvO5P8Et0oOQwgGDBzvQJ991ay7SvFbkivC-LxVatPnpAc5gMq5dCh4znEJfFXKGY05ZCizRgNLwH4Kz3Gmn6z1cKA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Differentiating Spitz naevi from melanomas can be difficult both clinically and dermoscopically. Previous studies have reported the potential role of in vivo reflectance confocal microscopy (RCM) in increasing diagnostic accuracy. Objectives To define RCM criteria that can differentiate ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13665" aria-hidden="true"></span> <span class="toc-heading-article-flag">Review Articles</span> <a class="journal-link" href="/bjd/article/172/6/1507/6615844?searchresult=1"> <div class="widget-dynamic-journal-title"> Smartphone applications for melanoma detection by community, patient and generalist clinician users: a review </div> </a> <div class="widget-dynamic-journal-authors"> A.P. Kassianos and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> Smartphone health applications (‘apps’) are widely available but experts remain cautious about their utility and safety. We reviewed currently available apps for the detection of melanoma (July 2014), aimed at general community, patient and generalist clinician users. A proforma was used to extract ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13500" aria-hidden="true"></span> <span class="toc-heading-article-flag">Systematic review</span> <a class="journal-link" href="/bjd/article/172/4/885/6615868?searchresult=1"> <div class="widget-dynamic-journal-title"> Socioeconomic and lifestyle factors and melanoma: a systematic review </div> </a> <div class="widget-dynamic-journal-authors"> A.J. Jiang and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/4/10.1111_bjd.13500/3/bjd13500-fig-0001.jpeg?Expires=1735462074&Signature=NKr2hMSDUevf4iXmLsIiSBluez3LjjRiZ8~7k12rMGA7VqWyOVaH9LARWyQpjYRXk3jWEZE4I-Xo-D4kllG~EU3LUZayRkcbotU5ecHKzBxpvnYWFp1QgzHOMBtNM9Ef4xBjmaE-D7FYn4l2kJytz3LoZKzmWI4uN-Qqf35alIUsbRw9UbeV0G4~pmgR~kLImtrRwj8Mt-nE5qUAlYAOWgcA0ShkOa6v5zvZIxu6MAUnAYMn7SsQRGyKn0bYoNMjTWMPMsfQT3fkNTYKmS~dHIkZVJMvqF37Uml9g9nHPTe1hzsX8JlkLllXyiO9l-9oR08Dl4aNqWqwNnC22nCDVw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Evidence of social determinants of disease and awareness of the impact of these factors on outcomes continues to increase. Social determinants include both socioeconomic and lifestyle factors. This review examines the interface between socioeconomic status (SES) and lifestyle and their effects on ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13756" aria-hidden="true"></span> <span class="toc-heading-article-flag">Clinical and laboratory investigations</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/1/76/6616855?searchresult=1"> <div class="widget-dynamic-journal-title"> The role of <em>BRAF</em> mutations in primary melanoma growth rate and survival </div> </a> <div class="widget-dynamic-journal-authors"> V.J. Mar and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/1/10.1111_bjd.13756/3/bjd13756-fig-0001.jpeg?Expires=1735462074&Signature=HxvgozwQHXSuZ6grH2tFTB98jewGgmGYXlkV0ZAOOOTJ7aJwmOdvTP8Q9bFLym8GrcQl~1Ul5-I4Fgd1LDVNF-Fpn5obR9J2u9XaEqCrS56s3HnI9zLNZYpIIuXSLSuQMvjj3-~ig~0sPRR2kzM1Kj4dJSPvtYZzDRFbWCuwotJyW0wJhIjgR7BJx4wMiMyTZ6Zi4waLj~KGdfatxUOJt-zgBMiCBgG~AbnZ1jNkeWnW5olmgCBt5eq2XHV345iDZyW-zqldy9w-u0sPMNeJJfxs6Nd5AeK9I1kCcWAH4i-7xp0x8tSxQ-HsFKs~hHxiTep9G5heStOBtEJ1QS2j9A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background The clinical behaviour and prognosis of primary melanomas harbouring BRAF mutations is not fully understood. Objectives To investigate the effect of mutation status on primary melanoma growth rate and melanoma‐specific survival (MSS). Methods A prospective cohort of 196 patients with ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14631" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/175/3/583/6616965?searchresult=1"> <div class="widget-dynamic-journal-title"> End‐of‐life care for hospitalized patients with metastatic melanoma in France: a nationwide, register‐based study </div> </a> <div class="widget-dynamic-journal-authors"> I. Gallais Sérézal and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/3/10.1111_bjd.14631/3/bjd14631-fig-0001.jpeg?Expires=1735462074&Signature=UqDt4sugDYdW~ERE1scVvkA5zuYUb5y-wZZbcL4UgcMz6Vw0ZS5Fne8iVIq0i1h8D5sQ-i4oabp-FckhqPtdg1fIB99YfYSYRHPEmvBfNceuuO-NsGffHWFg1Quzx6YgsLa5u2ltCsNwbX9sEv0zgeUEu80IMzEMch8HMgrmq6Plvx4eKJ75NIHx-9a-M5ZEPY5FW6lFCyxm7MTgqMRHpLA9chQyRHWdit7-umzAATtXdQoTSVsaZn5nmPcazcHmZVBY7WpwVCBFWBd1iIwgcB4o3q9~dYH5X~xYGE2kvMy3HhQwKddhIxHhzA-mcYcDgSQtoYan3oANiM5VIvHyFQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Although the aggressiveness of end‐of‐life cancer care has come under great scrutiny over the past two decades, little is known about the intensity of care and treatments in the last months of life of patients with metastatic melanoma. Objectives To measure the prevalence of aggressive ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13958" aria-hidden="true"></span> <span class="toc-heading-article-flag">MEDICAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/4/1024/6616001?searchresult=1"> <div class="widget-dynamic-journal-title"> Cutaneous toxicities associated with vemurafenib therapy in 107 patients with <em>BRAF</em> V600E mutation‐positive metastatic melanoma, including recognition and management of rare presentations </div> </a> <div class="widget-dynamic-journal-authors"> R. Sinha and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/4/10.1111_bjd.13958/3/bjd13958-fig-0001.jpeg?Expires=1735462074&Signature=wDnZ67JSAka7zHwZUXT7GnAezxztq~RJ6uvR2Xbcm40TcOBhFBGJj5OrOtHcUPullWly2Z3xQ-DqpH6DBNrSXSJ3udX4TsDwKytE4pYU8XtnSVJWxJLHrxjCTnz26OirCSHz3Bw6UMM5NagVZSn04RgWFsZe91uUXO2x-tpBiBrqSNruzB7RDOoEYXlcgBxFsJzuYaUtWjg1vSgr3ID-3KteeDR17xOR~bzqxH7vp8C2nN82Db1C5pVoF9BB~1oojtYECcmvnOTAYbMtczqpb~ZP--nGEq56KplsE-10P7YBiKz2MtttYVXDYZDW171fEVsR78VmrKXXZB-lRYQPGg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Vemurafenib significantly improved overall survival compared with dacarbazine in patients with metastatic or unresectable BRAF V600E‐positive melanoma in the BRIM‐3 trial. However, vemurafenib was associated with a number of skin‐related adverse events (AEs). Objectives To investigate ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.13301" aria-hidden="true"></span> <span class="toc-heading-article-flag">Clinical and laboratory investigations</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/172/3/662/6616120?searchresult=1"> <div class="widget-dynamic-journal-title"> CD271 is expressed in melanomas with more aggressive behaviour, with correlation of characteristic morphology by <em>in vivo</em> reflectance confocal microscopy </div> </a> <div class="widget-dynamic-journal-authors"> F. Beretti and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/172/3/10.1111_bjd.13301/3/bjd13301-fig-0001.jpeg?Expires=1735462074&Signature=BZqvtEIXXBEmC92xgVeIYLZuoDTwgTlW3lud-7S4E1Wap57kaivlbLr3tlLScoCvOpHtYM9HDk9yXZF72B1ZZ-sLDxEGGOZGeC0iZcYhBftba6wDtFUtU1oYphV3LJ2yEW6LBoEEQg6afZDjhY3HJCty3ylAlrV785EAeTTKmNLVnkdGIuHCA0dIXXsupAzbC2I9eyZx-ZCifxLnEWx~ADRJ~LqoZmqJw8L8TKOeH1pT05vJYKLHJ9vhZi25xni-HsDOjcSJpPLTHGMK~YnQuLKokE4UmWUlWEmMFDlDtMjEPlkH0vxYhnb6tTzwrsWSa2c8Dz9FfJzgLDaFYunVLw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Melanoma is the most highly aggressive type of skin cancer. Its resistance to existing treatments and the rapid rise in incidence underscore the importance of acquiring a better understanding of melanomagenesis. Objectives To assess the impact of reflectance confocal microscopy (RCM) on ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14045" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/173/4/1041/6616137?searchresult=1"> <div class="widget-dynamic-journal-title"> The BRAAFF checklist: a new dermoscopic algorithm for diagnosing acral melanoma </div> </a> <div class="widget-dynamic-journal-authors"> A. Lallas and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/173/4/10.1111_bjd.14045/3/bjd14045-fig-0001.jpeg?Expires=1735462074&Signature=L3vRkerMbBL7yKpKMN81NFEMVXtB-Tspt180t008zhBG3YhEdNtQQ5eXHF3ApbbcYeTK1IQaV5cEJBa0NujqgPVVxEUQYyjzEsTnNMpWHko2n~aDwHxmPYQizR8QP8JaQSafBwYCYPE6ctUKwQi0XuOBGnc--AvAPvYyYA9j9s3rUfLCbbp9Xdn3Be7IUBPoN~cFXxgJtJgV6~ceeTs6Pf0iSLh6Qtw1u8UUGrmHnVTcWi9-BNIHEHazNEGQ3wDz6joB4Yoxx4~5elTPW5IWbOJU59oYKzgTWzkxUAscDPyOv2iQ8t9bNWgV0UXKeSqf7vc2ScmMfKrskN2I79egSw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background The parallel ridge pattern (PRP) is considered the dermoscopic hallmark of acral melanoma (AM). However, it was recently shown that approximately one‐third of AMs do not display a PRP dermoscopically, rendering their detection more troublesome. Objectives To investigate the diagnostic ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.15181" aria-hidden="true"></span> <span class="toc-heading-article-flag">EPIDEMIOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/176/4/939/6748062?searchresult=1"> <div class="widget-dynamic-journal-title"> Identifying people at higher risk of melanoma across the U.K.: a primary‐care‐based electronic survey </div> </a> <div class="widget-dynamic-journal-authors"> J.A. Usher‐Smith and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/176/4/10.1111_bjd.15181/2/bjd15181-fig-0001.jpeg?Expires=1735462074&Signature=4PVhes9gqCIUkPa53uBYd1s0RQ22FVbxsLVQLwry5yUekxV3dfpUyvoqKsUgGM5B-CNoZoyUfJBtZwGlMh2o7RRcmmjHFFHLDaIBj8WmG~F1TxS7EghIXB3qVOZ7M-wABv2-JOiG0~cAJxXS3qZTWEO7qn0ZU3~if1bRvOOLFoLJuq2SCTQIojRYfPJBgjM2gexCZQQFv7hdV78A47R9lZPW~FASckpkObp-EuG3e0jVxI0nafGgOTq2zjhhNIisucXVmpzJJGS5sUOd-si92j0WASYE66GXP1wGRbwMJHRdZ0YmtJ4SI7ZallJgs32gCUqJslpHCuP3LPGl~gQ~Xw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Melanoma incidence is rising rapidly worldwide among white populations. Defining higher‐risk populations using risk prediction models may help targeted screening and early detection approaches. Objectives To assess the feasibility of identifying people at higher risk of melanoma using ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.14887" aria-hidden="true"></span> <span class="toc-heading-article-flag">GENERAL DERMATOLOGY</span> <span class="toc-heading-article-flag">Original Articles</span> <a class="journal-link" href="/bjd/article/175/5/1020/6697162?searchresult=1"> <div class="widget-dynamic-journal-title"> Invasive melanoma <em>in vivo</em> can be distinguished from basal cell carcinoma, benign naevi and healthy skin by canine olfaction: a proof‐of‐principle study of differential volatile organic compound emission </div> </a> <div class="widget-dynamic-journal-authors"> C.M. Willis and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/175/5/10.1111_bjd.14887/2/bjd14887-fig-0001.jpeg?Expires=1735462074&Signature=VQZ~27Br4FLxFXqnvioRFmf8BXVFspVFR9QpMe5q9YT4SHCF0mkXTDLzBE~WOMMBJIZkt2bPVbti0G31emv56c9wiksmqRWtOISPNy-g36kQOsfTNN6GYK61rGGlN0dZfxsIUFKiv5My81y38XQo-P-txgyAolXJbC9NHsxZCa4vdJdf1z6byNRmHhW~JWy61vYQN5-L2onwHyKHZ2rAI~WpRd-su2EDbdMV-X0Uwc1UPWBsDiCur1tNedeVsHbLfsSza787COKIKkgr3oftzK51lDmW9pkpkRsLVpESYWSdP3qn~1BHHSDtywy6W1DtX0RDfGd8ah0s3NI6cUcuHw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Background Volatile organic compounds (VOCs) are continuously released by the body during normal metabolic processes, but their profiles change in the presence of cancer. Robust evidence that invasive melanoma in vivo emits a characteristic VOC signature is lacking. Objectives To conduct a canine ... </div> </div> </div> <div class="widget-dynamic-entry journalArticleItem at-widget-entry-SCL"> <span class="hfDoi" data-attribute="10.1111/bjd.15385" aria-hidden="true"></span> <span class="toc-heading-article-flag">Editorials</span> <a class="journal-link" href="/bjd/article/178/1/1/6668376?searchresult=1"> <div class="widget-dynamic-journal-title"> A new era in holistic care: bridging the gap between dermatologists and oncologists for the treatment of malignant melanoma </div> </a> <div class="widget-dynamic-journal-authors"> S. Muthiah and others </div> <div class="widget-dynamic-journal-image-synopsis"> <div class="widget-dynamic-journal-synopsis"> <img src="https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/bjd/178/1/10.1111_bjd.15385/2/bjd15385-fig-0001.jpeg?Expires=1735462074&Signature=a1mZnhhToUqcigIjZdcTCPQK7oyfCVW0mU34wVFieRv11m7N1i3durSwAjUvHKs74ThY8kc917xSDL7xifYL1rkhlufBqxCBXOxjIy~EaEyR-qbpBSKmuXKInO48AJfzuXihFtBZH5dy6pXiZXiTrhNMSSTUG3zIkbV74RSiFZ6QwZThBnw~TZnpH0QPGolNKLAgxH4p~gQbhWRncQ5AJNc4rGjO3XsHGpN-s-50BihhABQPCKC-3JXnT7tojbRJ1FfyRoOadwB3zxDOEMIlmPz1n9kr1ccFoNC7E4TeDP56pALvm94A4kaocQFN9mxGRIojRM0OQmgJCQNWZqOVqQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA" width="115px" class="widget-dynamic-journal-featured-image" /> Melanoma is the most aggressive skin cancer with incidence rates rising by 360% in the last 30 years and projected to increase by a further 7% between 2014 and 2035. 1 Patients are referred to dermatology to make the diagnosis, excise the primary tumour and offer clinical surveillance. However, ... </div> </div> </div> </div> </div> </div> </div> </div> </div></div><div class="right"></div><script src="null"></script></div></div></div> </div> </div> </section> </div> <div class="mobile-mask"> </div> <section class="footer_wrap vt-site-footer"> <div class="ad-banner-footer sticky-footer-ad js-sticky-footer-ad"> <div class="widget widget-AdBlock widget-instance-StickyFooterAd"> <div class="js-adBlock-parent-wrap adblock-parent-wrap"> <div class="adBlockStickyFooter-wrap js-adBlockStickyFooter hide"> <div id="adBlockStickyFooter" class="js-adblock at-adblock" data-lazy-load-margin="150"> <script> googletag.cmd.push(function () { googletag.display('adBlockStickyFooter'); }); </script> </div> <div class="advertisement-text at-adblock js-adblock-advertisement-text hide">Advertisement intended for healthcare professionals</div> <button type="button" class="close-footer-ad js-close-footer-ad"> <span class="screenreader-text">close advertisement</span> </button> </div> </div> </div> </div> <div class="widget widget-SitePageFooter widget-instance-SitePageFooter"> <div class="ad-banner ad-banner-footer"> <div class="widget widget-AdBlock widget-instance-FooterAd"> <div class="js-adBlock-parent-wrap adblock-parent-wrap"> <div class="adBlockFooter-wrap js-adBlockFooter hide"> <div id="adBlockFooter" class="js-adblock at-adblock js-adblock-lazy-loading" data-lazy-load-margin="150"> <script> googletag.cmd.push(function () { googletag.display('adBlockFooter'); 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Malignant Melanoma | British Journal of Dermatology | Oxford Academic