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Dark cytotoxicities varied ten-fold, with EC50 values in the range of 10–100 µM and phototherapeutic indices (PIs) as large as 5,400 and 260 with broadband visible (28 J cm-2, 7.8 mW cm-2) and 625-nm red (100 J ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Bis[Pyrrolyl Ru(II)] Triads: a New Class of Photosensitizers for Metal-Organic Photodynamic Therapy","attachmentId":91673833,"attachmentType":"pdf","work_url":"https://www.academia.edu/87476502/Bis_Pyrrolyl_Ru_II_Triads_a_New_Class_of_Photosensitizers_for_Metal_Organic_Photodynamic_Therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/87476502/Bis_Pyrrolyl_Ru_II_Triads_a_New_Class_of_Photosensitizers_for_Metal_Organic_Photodynamic_Therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="31298869" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/31298869/Structures_and_Electronic_Absorption_Spectra_of_a_Recently_Synthesised_Class_of_Photodynamic_Therapy_Agents">Structures and Electronic Absorption Spectra of a Recently Synthesised Class of Photodynamic Therapy Agents</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32892559" href="https://unical-it.academia.edu/NinoRusso">Nino Russo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chemistry - A European Journal, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Structures and Electronic Absorption Spectra of a Recently Synthesised Class of Photodynamic Therapy Agents","attachmentId":51694925,"attachmentType":"pdf","work_url":"https://www.academia.edu/31298869/Structures_and_Electronic_Absorption_Spectra_of_a_Recently_Synthesised_Class_of_Photodynamic_Therapy_Agents","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/31298869/Structures_and_Electronic_Absorption_Spectra_of_a_Recently_Synthesised_Class_of_Photodynamic_Therapy_Agents"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="116367794" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/116367794/131I_Zn_Chlorophyll_derivative_photosensitizer_for_tumor_imaging_and_photodynamic_therapy">131I–Zn–Chlorophyll derivative photosensitizer for tumor imaging and photodynamic therapy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="61667517" href="https://independent.academia.edu/Fatmayurt">Fatma yurt</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Pharmaceutics, 2015</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"131I–Zn–Chlorophyll derivative photosensitizer for tumor imaging and photodynamic therapy","attachmentId":112518242,"attachmentType":"pdf","work_url":"https://www.academia.edu/116367794/131I_Zn_Chlorophyll_derivative_photosensitizer_for_tumor_imaging_and_photodynamic_therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/116367794/131I_Zn_Chlorophyll_derivative_photosensitizer_for_tumor_imaging_and_photodynamic_therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="23114825" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23114825/Potential_photosensitizers_for_photodynamic_therapy">Potential photosensitizers for photodynamic therapy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44888939" href="https://independent.academia.edu/FMontforts">F. Montforts</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Photochemistry and Photobiology B: Biology, 1994</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Potential photosensitizers for photodynamic therapy","attachmentId":43610845,"attachmentType":"pdf","work_url":"https://www.academia.edu/23114825/Potential_photosensitizers_for_photodynamic_therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23114825/Potential_photosensitizers_for_photodynamic_therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="114751888" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/114751888/Bis_pyrrolyl_Ru_scp_ii_scp_triads_a_new_class_of_photosensitizers_for_metal_organic_photodynamic_therapy">Bis[pyrrolyl Ru(<scp>ii</scp>)] triads: a new class of photosensitizers for metal–organic photodynamic therapy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="915812" href="https://independent.academia.edu/SusanMonro">Susan Monro</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chemical Science, 2020</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Bis[pyrrolyl Ru(\u003cscp\u003eii\u003c/scp\u003e)] triads: a new class of photosensitizers for metal–organic photodynamic therapy","attachmentId":111362920,"attachmentType":"pdf","work_url":"https://www.academia.edu/114751888/Bis_pyrrolyl_Ru_scp_ii_scp_triads_a_new_class_of_photosensitizers_for_metal_organic_photodynamic_therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/114751888/Bis_pyrrolyl_Ru_scp_ii_scp_triads_a_new_class_of_photosensitizers_for_metal_organic_photodynamic_therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="72300757" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/72300757/Recent_Emergence_of_Rhenium_I_Tricarbonyl_Complexes_as_Photosensitisers_for_Cancer_Therapy">Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50239102" href="https://independent.academia.edu/MZulkefeli">M. Zulkefeli</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Molecules</p><p class="ds-related-work--abstract ds2-5-body-sm">Photodynamic therapy (PDT) is emerging as a significant complementary or alternative approach for cancer treatment. PDT drugs act as photosensitisers, which upon using appropriate wavelength light and in the presence of molecular oxygen, can lead to cell death. Herein, we reviewed the general characteristics of the different generation of photosensitisers. We also outlined the emergence of rhenium (Re) and more specifically, Re(I) tricarbonyl complexes as a new generation of metal-based photosensitisers for photodynamic therapy that are of great interest in multidisciplinary research. The photophysical properties and structures of Re(I) complexes discussed in this review are summarised to determine basic features and similarities among the structures that are important for their phototoxic activity and future investigations. We further examined the in vitro and in vivo efficacies of the Re(I) complexes that have been synthesised for anticancer purposes. We also discussed Re(I) compl...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy","attachmentId":81282362,"attachmentType":"pdf","work_url":"https://www.academia.edu/72300757/Recent_Emergence_of_Rhenium_I_Tricarbonyl_Complexes_as_Photosensitisers_for_Cancer_Therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/72300757/Recent_Emergence_of_Rhenium_I_Tricarbonyl_Complexes_as_Photosensitisers_for_Cancer_Therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":110919206,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":110919206,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_110919206" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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data-collection-position="5" data-entity-id="27920249" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/27920249/Combination_of_Ru_II_Complexes_and_Light_New_Frontiers_in_Cancer_Therapy">Combination of Ru(II) Complexes and Light: New Frontiers in Cancer Therapy</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="52216979" href="https://uzh.academia.edu/StefanoFerrari">Stefano Ferrari</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chem. 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