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Koul</title> <meta name="description" content="Search results for: Vatasta Koul"> <meta name="keywords" content="Vatasta Koul"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="Vatasta Koul" name="q" aria-label="Search"> <button class="btn btn-light my-2 my-sm-0" type="submit"><i class="fas fa-search"></i></button> </form> </div> <div class="collapse navbar-collapse mt-1" id="navbarMenu"> <ul class="navbar-nav ml-auto align-items-center" id="mainNavMenu"> <li class="nav-item"> <a class="nav-link" href="https://waset.org/conferences" title="Conferences in 2024/2025/2026">Conferences</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/disciplines" title="Disciplines">Disciplines</a> </li> <li 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Vatasta Koul"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 7</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Vatasta Koul</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Dynamic Stall Characterization of Low Reynolds Airfoil in Mars and Titan’s Atmosphere</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vatasta%20Koul">Vatasta Koul</a>, <a href="https://publications.waset.org/abstracts/search?q=Vaibhav%20Sharma"> Vaibhav Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Ayush%20Gupta"> Ayush Gupta</a>, <a href="https://publications.waset.org/abstracts/search?q=Rajesh%20Yadav"> Rajesh Yadav</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Exploratory missions to Mars and Titan have increased recently with various endeavors to find an alternate home to humankind. The use of surface rovers has its limitations due to rugged and uneven surfaces of these planetary bodies. The use of aerial robots requires the complete aerodynamic characterization of these vehicles in the atmospheric conditions of these planetary bodies. The dynamic stall phenomenon is extremely important for rotary wings performance under low Reynolds number that can be encountered in Martian and Titan’s atmosphere. The current research focuses on the aerodynamic characterization and exploration of the dynamic stall phenomenon of two different airfoils viz. E387 and Selig-Donovan7003 in Martian and Titan’s atmosphere at low Reynolds numbers of 10000 and 50000. The two-dimensional numerical simulations are conducted using commercially available finite volume solver with multi-species non-reacting mixture of gases as the working fluid. The k-epsilon (k-ε) turbulence model is used to capture the unsteady flow separation and the effect of turbulence. The dynamic characteristics are studied at a fixed different constant rotational extreme of angles of attack. This study of airfoils at different low Reynolds number and atmospheric conditions on Mars and Titan will be resulting in defining the aerodynamic characteristics of these airfoils for unmanned aerial missions for outer space exploration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aerodynamics" title="aerodynamics">aerodynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=dynamic%20stall" title=" dynamic stall"> dynamic stall</a>, <a href="https://publications.waset.org/abstracts/search?q=E387" title=" E387"> E387</a>, <a href="https://publications.waset.org/abstracts/search?q=SD7003" title=" SD7003"> SD7003</a> </p> <a href="https://publications.waset.org/abstracts/117445/dynamic-stall-characterization-of-low-reynolds-airfoil-in-mars-and-titans-atmosphere" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/117445.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">134</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Effect of Wavy Leading-Edges on Wings in Different Planetary Atmospheres</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vatasta%20Koul">Vatasta Koul</a>, <a href="https://publications.waset.org/abstracts/search?q=Ayush%20Gupta"> Ayush Gupta</a>, <a href="https://publications.waset.org/abstracts/search?q=Vaibhav%20Sharma"> Vaibhav Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Rajesh%20Yadav"> Rajesh Yadav</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Today we are unmarking the secrets of the universe by exploring different stars and planets and most of the space exploration is done by unmanned space robots. In addition to our planet Earth, there are pieces of evidence that show other astronomical objects in our solar system such as Venus, Mars, Saturn’s moon Titan and Uranus support the flight of fixed wing air vehicles. In this paper, we take forward the concept of presence of large rounded tubercles along the leading edge of a wing and use it as a passive flow control device that will help in improving its aerodynamic performance and maneuverability. Furthermore, in this research, aerodynamic measurements and performance analysis of wavy leading tubercles on the fixed wings at 5-degree angle of attack are carried out after determination of the flow conditions on the selected planetary bodies. Wavelength and amplitude for the sinusoidal modifications on the leading edge are analyzed and simulations are carried out for three-dimensional NACA 0012 airfoil maintaining unity AR (Aspect Ratio). Tubercles have consistently demonstrated the ability to delay and decrease the severity of stall as per the studies were done in the Earth’s atmosphere. Implementing the same design on the leading edges of Micro-Air Vehicles (MAVs) and UAVs could make these aircrafts more stable over a greater range of angles of attack in different planetary environments of our solar system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=amplitude" title="amplitude">amplitude</a>, <a href="https://publications.waset.org/abstracts/search?q=NACA0012" title=" NACA0012"> NACA0012</a>, <a href="https://publications.waset.org/abstracts/search?q=tubercles" title=" tubercles"> tubercles</a>, <a href="https://publications.waset.org/abstracts/search?q=unmanned%20space%20robots" title=" unmanned space robots"> unmanned space robots</a> </p> <a href="https://publications.waset.org/abstracts/117446/effect-of-wavy-leading-edges-on-wings-in-different-planetary-atmospheres" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/117446.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">146</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Spectroscopic Relation between Open Cluster and Globular Cluster</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Robin%20Singh">Robin Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayank%20Nautiyal"> Mayank Nautiyal</a>, <a href="https://publications.waset.org/abstracts/search?q=Priyank%20Jain"> Priyank Jain</a>, <a href="https://publications.waset.org/abstracts/search?q=Vatasta%20Koul"> Vatasta Koul</a>, <a href="https://publications.waset.org/abstracts/search?q=Vaibhav%20Sharma"> Vaibhav Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The curiosity to investigate the space and its mysteries was dependably the main impetus of human interest, as the particle of livings exists from the "debut de l'Univers" (beginning of the Universe) typified with its few other living things. The sharp drive to uncover the secrets of stars and their unusual deportment was dependably an ignitor of stars investigation. As humankind lives in civilizations and states, stars likewise live in provinces named ‘clusters’. Clusters are separates into 2 composes i.e. open clusters and globular clusters. An open cluster is a gathering of thousand stars that were moulded from a comparable goliath sub-nuclear cloud and for the most part; contain Propulsion I (extremely metal-rich) and Propulsion II (mild metal-rich), where globular clusters are around gathering of more than thirty thousand stars that circles a galactic focus and basically contain Propulsion III (to a great degree metal-poor) stars. Futurology of this paper lies in the spectroscopic investigation of globular clusters like M92 and NGC419 and open clusters like M34 and IC2391 in different color bands by using software like VIREO virtual observatory, Aladin, CMUNIWIN, and MS-Excel. Assessing the outcome Hertzsprung-Russel (HR) diagram with exemplary cosmological models like Einstein model, De Sitter and Planck survey demonstrate for a superior age estimation of respective clusters. Colour-Magnitude Diagram of these clusters was obtained by photometric analysis in g and r bands which further transformed into BV bands which will unravel the idea of stars exhibit in the individual clusters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=color%20magnitude%20diagram" title="color magnitude diagram">color magnitude diagram</a>, <a href="https://publications.waset.org/abstracts/search?q=globular%20clusters" title=" globular clusters"> globular clusters</a>, <a href="https://publications.waset.org/abstracts/search?q=open%20clusters" title=" open clusters"> open clusters</a>, <a href="https://publications.waset.org/abstracts/search?q=Einstein%20model" title=" Einstein model"> Einstein model</a> </p> <a href="https://publications.waset.org/abstracts/96685/spectroscopic-relation-between-open-cluster-and-globular-cluster" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96685.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">226</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Intrinsically Dual-Doped Conductive Polymer System for Electromagnetic Shielding Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Koul">S. Koul</a>, <a href="https://publications.waset.org/abstracts/search?q=Joshua%20Adedamola"> Joshua Adedamola</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Currently, the global concerning fact about electromagnetic pollution (EMP) is that it not only adversely affects human health but rather projects the malfunctioning of sensitive equipment both locally and at a global level. The market offers many incumbent technologies to solve the issues, but still, a processable sustainable material solution with acceptable limits for GHG emission is still at an exploratory stage. The present work offers a sustainable material solution with a wide range of processability in terms of a polymeric resin matrix and shielding operational efficiency across the electromagnetic spectrum, covering both ionizing and non-ionizing electromagnetic radiations. The present work offers an in-situ synthesized conducting polyaniline (PANI) in the presence of the hybrid dual dopant system with tuned conductivity and high shielding efficiency between 89 to 92 decibels, depending upon the EMI frequency range. The conductive polymer synthesized in the presence of a hybrid dual dopant system via the in-situ emulsion polymerization method offers a higher surface resistance of 1.0 ohms/cm with thermal stability up to 2450C in their powder form. This conductive polymer with a hybrid dual dopant system was used as a filler material with different polymeric thermoplastic resin systems for the preparation of conductive composites. Intrinsically Conductive polymeric (ICP) composites based on hybrid dual dopant systems were prepared using melt blending, extrusion, and finally by, compression molding processing techniques. ICP composites with hybrid dual dopant systems offered good mechanical, thermal, structural, weathering, and stable surface resistivity properties over a period of time. The preliminary shielding behavior for ICP composites between frequency levels of 10 GHz to 24GHZ offered a shielding efficiency of more than 90 dB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ICP" title="ICP">ICP</a>, <a href="https://publications.waset.org/abstracts/search?q=dopant" title=" dopant"> dopant</a>, <a href="https://publications.waset.org/abstracts/search?q=EMI" title=" EMI"> EMI</a>, <a href="https://publications.waset.org/abstracts/search?q=shielding" title=" shielding"> shielding</a> </p> <a href="https://publications.waset.org/abstracts/164742/intrinsically-dual-doped-conductive-polymer-system-for-electromagnetic-shielding-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/164742.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">81</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Dosimetric Application of α-Al2O3:C for Food Irradiation Using TA-OSL</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Soni">A. Soni</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20R.%20Mishra"> D. R. Mishra</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20K.%20Koul"> D. K. Koul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> α-Al2O3:C has been reported to have deeper traps at 600°C and 900°C respectively. These traps have been reported to accessed at relatively earlier temperatures (122 and 322 °C respectively) using thermally assisted OSL (TA-OSL). In this work, the dose response α-Al2O3:C was studied in the dose range of 10Gy to 10kGy for its application in food irradiation in low ( upto 1kGy) and medium(1 to 10kGy) dose range. The TOL (Thermo-optically stimulated luminescence) measurements were carried out on RisØ TL/OSL, TL-DA-15 system having a blue light-emitting diodes (λ=470 ±30nm) stimulation source with power level set at the 90% of the maximum stimulation intensity for the blue LEDs (40 mW/cm2). The observations were carried on commercial α-Al2O3:C phosphor. The TOL experiments were carried out with number of active channel (300) and inactive channel (1). Using these settings, the sample is subjected to linear thermal heating and constant optical stimulation. The detection filter used in all observations was a Hoya U-340 (Ip ~ 340 nm, FWHM ~ 80 nm). Irradiation of the samples was carried out using a 90Sr/90Y β-source housed in the system. A heating rate of 2 °C/s was preferred in TL measurements so as to reduce the temperature lag between the heater plate and the samples. To study the dose response of deep traps of α-Al2O3:C, samples were irradiated with various dose ranging from 10 Gy to 10 kGy. For each set of dose, three samples were irradiated. In order to record the TA-OSL, initially TL was recorded up to a temperature of 400°C, to deplete the signal due to 185°C main dosimetry TL peak in α-Al2O3:C, which is also associated with the basic OSL traps. After taking TL readout, the sample was subsequently subjected to TOL measurement. As a result, two well-defined TA-OSL peaks at 121°C and at 232°C occur in time as well as temperature domain which are different from the main dosimetric TL peak which occurs at ~ 185°C. The linearity of the integrated TOL signal has been measured as a function of absorbed dose and found to be linear upto 10kGy. Thus, it can be used for low and intermediate dose range of for its application in food irradiation. The deep energy level defects of α-Al2O3:C phosphor can be accessed using TOL section of RisØ reader system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=%CE%B1-Al2O3%3AC" title="α-Al2O3:C">α-Al2O3:C</a>, <a href="https://publications.waset.org/abstracts/search?q=deep%20traps" title=" deep traps"> deep traps</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20irradiation" title=" food irradiation"> food irradiation</a>, <a href="https://publications.waset.org/abstracts/search?q=TA-OSL" title=" TA-OSL"> TA-OSL</a> </p> <a href="https://publications.waset.org/abstracts/46419/dosimetric-application-of-a-al2o3c-for-food-irradiation-using-ta-osl" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46419.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">299</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Aloe vera Prevents Injuries Induced by Whole Body X-ray Irradiation in Rodents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shashi%20Bala">Shashi Bala</a>, <a href="https://publications.waset.org/abstracts/search?q=Neha%20A.%20Chugh"> Neha A. Chugh</a>, <a href="https://publications.waset.org/abstracts/search?q=Subhash%20C.%20Bansal"> Subhash C. Bansal</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohal%20L.%20Garg"> Mohal L. Garg</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashwani%20Koul"> Ashwani Koul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: The present study was designed to evaluate the radioprotective efficacy of Aloe vera from whole body X-ray exposure in rodents. Materials and Methods: For this purpose, after on week’s acclimatization, male balb/c mice procured from Central Animal House, Panjab University, Chandigarh (India), were divided into four groups: Group I mice served as control. Group II mice were orally administrated Aloe vera pulp extract (50 mg/ kg body weight) on alternate days for 30 days. Group III mice were subjected to whole body X-ray irradiation to cumulative dose of 2Gy (0.258Gy twice a day for four days in the last week). Group IV animals were pretreated with Aloe vera pulp extract on alternate days as in Group II and in the last week of the study, they were exposed to X-ray as in Group III. Results: Spleen of X-ray irradiated mice showed histopathological alterations accompanied with enhanced activity of lactate dehydrogenase (LDH) in serum. Elevated levels of reactive oxygen species (ROS), lipid peroxidation (LPO), enhanced activities in Glutathione based enzymes such as Glutathione peroxidase (GSH-Px), Glutathione reductase (GR), Catalase (CAT), Superoxide dismutase (SOD) associated with depletion in reduced Glutathione (GSH) concentration were observed after X-ray exposure in blood plasma and spleen.. Pro-inflammatory cytokines like tumor necrosis factors (TNF-α) and Inteleukin-6 (IL-6) levels were also found to be enhanced in serum of irradiated mice. Irradiation-induced significant elevation in Total leucocyte counts (TLC), neutrophil counts and decline in platelet counts, associated with unaltered levels of red blood cell counts (RBC’s) and haemoglobin (Hb) in various treatment groups. Clastogenic damage and apoptosis was also found to be increase in splenic tissue of X-ray exposed mice as assessed by micronucleus and TUNEL assay. However, X-ray irradiated animals administered with Aloe vera revealed significant improvement in levels of ROS/ LPO, LDH activity, and antioxidant mechanism. Aloe vera pretreated animals exhibited less severe damage, and early recovery in micronucleated cells, hematological parameters, apoptotic cells and inflammatory markers as compared to X-ray exposed mice. Conclusion: These results indicate that the radioprotective potential of Aloe vera against X-ray induced damage. This may be due to its free radical scavenging, antioxidant, anti-apoptotic and anti-inflammatory properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aloe%20vera" title="aloe vera">aloe vera</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20defense%20system" title=" antioxidant defense system"> antioxidant defense system</a>, <a href="https://publications.waset.org/abstracts/search?q=lactate%20dehydrogenase%20%28LDH%29" title=" lactate dehydrogenase (LDH)"> lactate dehydrogenase (LDH)</a>, <a href="https://publications.waset.org/abstracts/search?q=micronucleus%20assay" title=" micronucleus assay"> micronucleus assay</a>, <a href="https://publications.waset.org/abstracts/search?q=x-ray" title=" x-ray"> x-ray</a> </p> <a href="https://publications.waset.org/abstracts/76802/aloe-vera-prevents-injuries-induced-by-whole-body-x-ray-irradiation-in-rodents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76802.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">192</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Anticancer Potentials of Aqueous Tinospora cordifolia and Its Bioactive Polysaccharide, Arabinogalactan on Benzo(a)Pyrene Induced Pulmonary Tumorigenesis: A Study with Relevance to Blood Based Biomarkers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vandana%20Mohan">Vandana Mohan</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashwani%20%20Koul"> Ashwani Koul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aim: To evaluate the potential of Aqueous Tinospora cordifolia stem extract (Aq.Tc) and Arabinogalactan (AG) on pulmonary carcinogenesis and associated tumor markers. Background: Lung cancer is one of the most frequent malignancy with high mortality rate due to limitation of early detection resulting in low cure rates. Current research effort focuses on identifying some blood-based biomarkers like CEA, ctDNA and LDH which may have potential to detect cancer at an early stage, evaluation of therapeutic response and its recurrence. Medicinal plants and their active components have been widely investigated for their anticancer potentials. Aqueous preparation of T. Cordifolia extract is enriched in the polysaccharide fraction i.e., AG when compared with other types of extract. Moreover, reports are available of polysaccharide fraction of T. Cordifolia in in vitro lung cancer models which showed profound anti-metastatic activity against these cell lines. However, not much has been explored about its effect in in vivo lung cancer models and the underlying mechanism involved. Experimental Design: Mice were randomly segregated into six groups. Group I animals served as control. Group II animals were administered with Aq. Tc extract (200 mg/kg b.w.) p.o.on the alternate days. Group III animals were fed with AG (7.5 mg/kg b.w.) p.o. on the alternate days (thrice a week). Group IV animals were installed with Benzo(a)pyrene (50 mg/kg b.w.), i.p. twice within an interval of two weeks. Group V animals received Aq. Tc extract as in group II along with it B(a)P was installed after two weeks of Aq. Tc administration following the same protocol as for group IV. Group VI animals received AG as in group III along with it B(a)P was installed after two weeks of AG administration. Results: Administration of B(a)P to mice resulted in increased tumor incidence, multiplicity and pulmonary somatic index with concomitant increase in serum/plasma markers like CEA, ctDNA, LDH and TNF-α.Aq.Tc and AG supplementation significantly attenuated these alterations at different stages of tumorigenesis thereby showing potent anti-cancer effect in lung cancer. A pronounced decrease in serum/plasma markers were observed in animals treated with Aq.Tc as compared to those fed with AG. Also, extensive hyperproliferation of alveolar epithelium was prominent in B(a)P induced lung tumors. However, treatment of Aq.Tc and AG to lung tumor bearing mice exhibited reduced alveolar damage evident from decreased number of hyperchromatic irregular nuclei. A direct correlation between the concentration of tumor markers and the intensity of lung cancer was observed in animals bearing cancer co-treated with Aq.Tc and AG. Conclusion: These findings substantiate the chemopreventive potential of Aq.Tc and AG against lung tumorigenesis. Interestingly, Aq.Tc was found to be more effective in modulating the cancer as reflected by various observations which may be attributed to the synergism offered by various components of Aq.Tc. Further studies are in progress to understand the underlined mechanism in inhibiting lung tumorigenesis by Aq.Tc and AG. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Arabinogalactan" title="Arabinogalactan">Arabinogalactan</a>, <a href="https://publications.waset.org/abstracts/search?q=Benzo%28a%29pyrene%20B%28a%29P" title=" Benzo(a)pyrene B(a)P"> Benzo(a)pyrene B(a)P</a>, <a href="https://publications.waset.org/abstracts/search?q=carcinoembryonic%20antigen%20%28CEA%29" title=" carcinoembryonic antigen (CEA)"> carcinoembryonic antigen (CEA)</a>, <a href="https://publications.waset.org/abstracts/search?q=circulating%20tumor%20DNA%20%28ctDNA%29" title=" circulating tumor DNA (ctDNA)"> circulating tumor DNA (ctDNA)</a>, <a href="https://publications.waset.org/abstracts/search?q=lactate%20dehydrogenase%20%28LDH%29" title=" lactate dehydrogenase (LDH)"> lactate dehydrogenase (LDH)</a>, <a href="https://publications.waset.org/abstracts/search?q=Tinospora%20cordifolia" title=" Tinospora cordifolia"> Tinospora cordifolia</a> </p> <a href="https://publications.waset.org/abstracts/76805/anticancer-potentials-of-aqueous-tinospora-cordifolia-and-its-bioactive-polysaccharide-arabinogalactan-on-benzoapyrene-induced-pulmonary-tumorigenesis-a-study-with-relevance-to-blood-based-biomarkers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76805.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">185</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a 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