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Search results for: M. Rizk
<!DOCTYPE html> <html lang="en" dir="ltr"> <head> <!-- Google tag (gtag.js) --> <script async src="https://www.googletagmanager.com/gtag/js?id=G-P63WKM1TM1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-P63WKM1TM1'); </script> <!-- Yandex.Metrika counter --> <script type="text/javascript" > (function(m,e,t,r,i,k,a){m[i]=m[i]||function(){(m[i].a=m[i].a||[]).push(arguments)}; m[i].l=1*new Date(); for (var j = 0; j < document.scripts.length; j++) {if (document.scripts[j].src === r) { return; }} k=e.createElement(t),a=e.getElementsByTagName(t)[0],k.async=1,k.src=r,a.parentNode.insertBefore(k,a)}) (window, document, "script", "https://mc.yandex.ru/metrika/tag.js", "ym"); ym(55165297, "init", { clickmap:false, trackLinks:true, accurateTrackBounce:true, webvisor:false }); </script> <noscript><div><img src="https://mc.yandex.ru/watch/55165297" style="position:absolute; left:-9999px;" alt="" /></div></noscript> <!-- /Yandex.Metrika counter --> <!-- Matomo --> <!-- End Matomo Code --> <title>Search results for: M. Rizk</title> <meta name="description" content="Search results for: M. Rizk"> <meta name="keywords" content="M. Rizk"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="M. 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Rizk"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 12</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: M. Rizk</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Co-Evolutionary Fruit Fly Optimization Algorithm and Firefly Algorithm for Solving Unconstrained Optimization Problems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20M.%20Rizk-Allah">R. M. Rizk-Allah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents co-evolutionary fruit fly optimization algorithm based on firefly algorithm (CFOA-FA) for solving unconstrained optimization problems. The proposed algorithm integrates the merits of fruit fly optimization algorithm (FOA), firefly algorithm (FA) and elite strategy to refine the performance of classical FOA. Moreover, co-evolutionary mechanism is performed by applying FA procedures to ensure the diversity of the swarm. Finally, the proposed algorithm CFOA- FA is tested on several benchmark problems from the usual literature and the numerical results have demonstrated the superiority of the proposed algorithm for finding the global optimal solution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=firefly%20algorithm" title="firefly algorithm">firefly algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=fruit%20fly%20optimization%20algorithm" title=" fruit fly optimization algorithm"> fruit fly optimization algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=unconstrained%20optimization%20problems" title=" unconstrained optimization problems"> unconstrained optimization problems</a> </p> <a href="https://publications.waset.org/abstracts/15923/co-evolutionary-fruit-fly-optimization-algorithm-and-firefly-algorithm-for-solving-unconstrained-optimization-problems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15923.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">536</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> The Agile Management and Its Relationship to Administrative Ambidexterity: An Applied Study in Alexandria Library</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samar%20Sheikhelsouk">Samar Sheikhelsouk</a>, <a href="https://publications.waset.org/abstracts/search?q=Dina%20Abdel%20Qader"> Dina Abdel Qader</a>, <a href="https://publications.waset.org/abstracts/search?q=Nada%20Rizk"> Nada Rizk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The plan of the organization may impede its progress and creativity, especially in the framework of its work in independent environments and fast-shifting markets, unless the leaders and minds of the organization use a set of practices, tools, and techniques encapsulated in so-called “agile methods” or “lightweight” methods. Thus, this research paper examines the agile management approach as a flexible and dynamic approach and its relationship to the administrative ambidexterity at the Alexandria library. The sample of the study is the employees of the Alexandria library. The study is expected to provide both theoretical and practical implications. The current study will bridge the gap between agile management and administrative approaches in the literature. The study will lead managers to comprehend how the role of agile management in establishing administrative ambidexterity in the organization. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=agile%20management" title="agile management">agile management</a>, <a href="https://publications.waset.org/abstracts/search?q=administrative%20innovation" title=" administrative innovation"> administrative innovation</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexandria%20library" title=" Alexandria library"> Alexandria library</a>, <a href="https://publications.waset.org/abstracts/search?q=Egypt" title=" Egypt"> Egypt</a> </p> <a href="https://publications.waset.org/abstracts/162587/the-agile-management-and-its-relationship-to-administrative-ambidexterity-an-applied-study-in-alexandria-library" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/162587.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">85</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Efficient Control of Brushless DC Motors with Pulse Width Modulation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Shahzadi">S. Shahzadi</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Rizk"> J. Rizk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper describes the pulse width modulated control of a three phase, 4 polar DC brushless motor. To implement this practically the Atmel’s AVR ATmega 328 microcontroller embedded on an Arduino Eleven board is utilized. The microcontroller programming is done in an open source Arduino IDE development environment. The programming logic effectively manipulated a six MOSFET bridge which was used to energize the stator windings as per control requirements. The results obtained showed accurate, precise and efficient pulse width modulated operation. Another advantage offered by this pulse width modulated control was the efficient speed control of the motor. By varying the time intervals between successive commutations, faster energizing of the stator windings was possible thereby leading to quicker rotor alignment with these energized phases and faster revolutions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=brushless%20DC%20motors" title="brushless DC motors">brushless DC motors</a>, <a href="https://publications.waset.org/abstracts/search?q=commutation" title=" commutation"> commutation</a>, <a href="https://publications.waset.org/abstracts/search?q=MOSFET" title=" MOSFET"> MOSFET</a>, <a href="https://publications.waset.org/abstracts/search?q=PWM" title=" PWM"> PWM</a> </p> <a href="https://publications.waset.org/abstracts/32239/efficient-control-of-brushless-dc-motors-with-pulse-width-modulation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32239.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">512</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Finite Element Analysis of High Performance Synchronous Reluctance Machines</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T.%20Mohanarajah">T. Mohanarajah</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Rizk"> J. Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Nagrial"> M. Nagrial</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Hellany"> A. Hellany</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper analyses numerous features of the synchronous Reluctance Motor (Syn-RM) and propose a rotor for high electrical torque, power factor & efficiency using Finite Element Method (FEM). A comprehensive analysis completed on solid rotor structure while the total thickness of the flux guide kept constant. A number of tests carried out for nine different studies to find out optimum location of the flux guide, the optimum location of multiple flux guides & optimum wall thickness between flux guides for high-performance reluctance machines. The results are concluded with the aid of FEM simulation results, the saliency ratio and machine characteristics (location, a number of barriers & wall width) analysed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electrical%20machines" title="electrical machines">electrical machines</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20method" title=" finite element method"> finite element method</a>, <a href="https://publications.waset.org/abstracts/search?q=synchronous%20reluctance%20machines" title=" synchronous reluctance machines"> synchronous reluctance machines</a>, <a href="https://publications.waset.org/abstracts/search?q=variable%20reluctance%20machines" title=" variable reluctance machines"> variable reluctance machines</a> </p> <a href="https://publications.waset.org/abstracts/32219/finite-element-analysis-of-high-performance-synchronous-reluctance-machines" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32219.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">485</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Comparison of Conventional Control and Robust Control on Double-Pipe Heat Exchanger</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hanan%20Rizk">Hanan Rizk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A heat exchanger is a device used to mix liquids having different temperatures. In this case, the temperature control becomes a critical objective. This research work presents the temperature control of the double-pipe heat exchanger (multi-input multi-output (MIMO) system), which is modeled as first-order coupled hyperbolic partial differential equations (PDEs), using conventional and advanced control techniques and develops appropriate robust control strategy to meet stability requirements and performance objectives. We designed a PID controller and H-infinity controller for a heat exchanger (HE) system. Frequency characteristics of sensitivity functions and open-loop and closed-loop time responses are simulated using MATLAB software, and the stability of the system is analyzed using Kalman's test. The simulation results have demonstrated that the H-infinity controller is more efficient than PID in terms of robustness and performance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=heat%20exchanger" title="heat exchanger">heat exchanger</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-input%20multi-output%20system" title=" multi-input multi-output system"> multi-input multi-output system</a>, <a href="https://publications.waset.org/abstracts/search?q=MATLAB%20simulation" title=" MATLAB simulation"> MATLAB simulation</a>, <a href="https://publications.waset.org/abstracts/search?q=partial%20differential%20equations" title=" partial differential equations"> partial differential equations</a>, <a href="https://publications.waset.org/abstracts/search?q=PID%20controller" title=" PID controller"> PID controller</a>, <a href="https://publications.waset.org/abstracts/search?q=robust%20control" title=" robust control"> robust control</a> </p> <a href="https://publications.waset.org/abstracts/138748/comparison-of-conventional-control-and-robust-control-on-double-pipe-heat-exchanger" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138748.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">220</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Evaluation of in vitro Inhibitory Effect of Enoxacin on Babesia and Theileria Parasites</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mosaab%20A.%20Omar">Mosaab A. Omar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Saleh%20Al-Aboody"> Mohammad Saleh Al-Aboody</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohmed%20A.%20Rizk"> Mohmed A. Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=Shimaa%20M.%20Elsayed"> Shimaa M. Elsayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20ElSify"> Ahmed ElSify</a>, <a href="https://publications.waset.org/abstracts/search?q=Naoaki%20Yokoyama"> Naoaki Yokoyama</a>, <a href="https://publications.waset.org/abstracts/search?q=Ikuo%20Igarashi"> Ikuo Igarashi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid used mainly in the treatment of urinary tract infections and gonorrhea. Also, it has been shown recently that it may have cancer inhibiting effect. The primary antibabesial effect of Enoxacin is due to inhibition of DNA gyrase subunit A, and DNA topoisomerase. In the present study, enoxacin was tested as a potent inhibitor against the in vitro growth of bovine and equine Piroplasms. The in vitro growth of five Babesia species that were tested was significantly inhibited (P<0.05) by micromolar concentrations of enoxacin (IC50 values= 13.5, 7.2, 7.5, and 24.2 µM for Babesia bovis, Babesia bigemina, Babesia caballi, and Theileria equi, respectively). Enoxacin IC50 values for Babesia and Theileria parasites were satisfactory as the drug is a potent antibacterial drug with minimum side effects. Therefore, enoxacin might be used for the treatment of Babesiosis and Theileriosis especially in case of mixed infections with bacterial diseases or in the case of animal sensitivity against diminazin toxicity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=enoxacin" title="enoxacin">enoxacin</a>, <a href="https://publications.waset.org/abstracts/search?q=Babesia" title=" Babesia"> Babesia</a>, <a href="https://publications.waset.org/abstracts/search?q=Theileria" title=" Theileria"> Theileria</a>, <a href="https://publications.waset.org/abstracts/search?q=IC50%20and%20dimenazin" title=" IC50 and dimenazin"> IC50 and dimenazin</a> </p> <a href="https://publications.waset.org/abstracts/24342/evaluation-of-in-vitro-inhibitory-effect-of-enoxacin-on-babesia-and-theileria-parasites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24342.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">468</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Calibrations and Effect of Different Operating Conditions on the Performance of a Fluid Power Control System with Servo Solenoid Valve</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tahany%20W.%20Sadak">Tahany W. Sadak</a>, <a href="https://publications.waset.org/abstracts/search?q=Fouly"> Fouly</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Anwer"> A. Anwer</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Rizk"> M. Rizk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The current investigation presents a study on the hydraulic performance of an electro-hydraulic servo solenoid valve controlled linear piston used in hydraulic systems. Advanced methods have been used to measure and record laboratory experiments, to ensure accurate analysis and evaluation. Experiments have been conducted under different values of temperature (28, 40 and 50 °C), supply pressure (10, 20, 30, 40 and 50 bar), system stiffness (32 N/mm), and load (0.0 & 5560 N). It is concluded that increasing temperature of hydraulic oil increases the quantity of flow rate, so it achieves an increase of the quantity of flow by 5.75 % up to 48.8 % depending on operating conditions. The values of pressure decay at low temperature are less than the values at high temperature. The frequency increases with the increase of the temperature. When we connect the springs to the system, it decreases system frequency. These results are very useful in the process of packing and manufacturing of fluid products, where the properties are not affected by 50 °C, so energy and time are saved. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electro-hydraulic%20servo%20valve" title="electro-hydraulic servo valve">electro-hydraulic servo valve</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid%20power%20control%20system" title=" fluid power control system"> fluid power control system</a>, <a href="https://publications.waset.org/abstracts/search?q=system%20stiffness" title=" system stiffness"> system stiffness</a>, <a href="https://publications.waset.org/abstracts/search?q=static%20and%20dynamic%20performance" title=" static and dynamic performance"> static and dynamic performance</a> </p> <a href="https://publications.waset.org/abstracts/98470/calibrations-and-effect-of-different-operating-conditions-on-the-performance-of-a-fluid-power-control-system-with-servo-solenoid-valve" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98470.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Affordable and Sustainable Housing Construction: Case Studies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tony%20Rizk">Tony Rizk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Recent material advances and cost efficiencies are transforming the housing industry away from traditional lumber and gypsum material to alternate fiberboard material that is workable and resistant to fire, mold, and pest infestation. The use of these materials may add to the initial cost of construction. However, the life cycle (cradle to grave) cost of houses using these construction materials and methods are lower than the life cycle costs using traditional housing construction materials and methods. This paper will present four (4) case studies of sustainable house projects. Each project was designed and constructed using earthen-based, sustainable fiberboard material that is resistant to fire, mold, and infestation and fabricated at a very low material calorific value. These house projects have a living space ranging from 625 sq. ft. for an accessory dwelling unit and up to 3,200 sq. ft. 1-story and 2-story homes. For each case study, we will present the house engineering design and construction method, the initial construction costs, a summary of the life cycle costs, and a comparison to the life cycle cost of traditional housing available in the literature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=residential%20housing" title="residential housing">residential housing</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainable%20housing" title=" sustainable housing"> sustainable housing</a>, <a href="https://publications.waset.org/abstracts/search?q=life%20cycle%20cost" title=" life cycle cost"> life cycle cost</a>, <a href="https://publications.waset.org/abstracts/search?q=fire%20resistance" title=" fire resistance"> fire resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=mold" title=" mold"> mold</a>, <a href="https://publications.waset.org/abstracts/search?q=infestation%20resistance" title=" infestation resistance"> infestation resistance</a> </p> <a href="https://publications.waset.org/abstracts/151099/affordable-and-sustainable-housing-construction-case-studies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151099.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Amelioration of Over-Expression of bax, Nrf2 and NFК–β in Nano-Sized Titanium Dioxide-Intoxicated Mice by Potent Antioxidants </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maha%20Z.%20Rizk">Maha Z. Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=Sami%20A.%20Fattah"> Sami A. Fattah</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20M.%20Darwish"> Heba M. Darwish</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanaa%20A.%20Ali"> Sanaa A. Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Mai%20O.%20Kadry"> Mai O. Kadry </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The increasing use of nanomaterials in consumer and industrial products has aroused global concern regarding their fate in biological systems resulting in demand for parallel risk assessment. The objective of this study is investigating either the effect of individual or combined doses of idebenone, carnosine and vitamin E on amelioration of some biochemical indices of nano sized titanium dioxide (TiO2 NPS) induced metabolic disorders in mice liver. TiO2-NPS was administered in an oral dose of 150 mg/kg for consecutive 14 days followed by oral daily doses of the aforementioned antioxidants for 1 month. TiO2-NPS induced a significant elevation in serum level of ALT and AST, hepatic inflammatory markers (tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6)) and increased the percent of DNA damage which was assessed by COMET assay in addition to the apoptotic marker Caspase-3. Moreover, mRNA gene expression observed by RT-PCR showed a significant overexpression in nuclear factor relation-2 (Nrf2), nuclear factor kappa beta (NF-Kβ) and the apoptotic factor (bax), and a significant down-regulation in the antiapoptotic factor (bcl2) level. In conclusion, idebenone, carnosine and vitamin E ameliorated the deviated parameters with a variable degree with the most pronounced role in alleviating the hazardous effect of TiO2 NPS toxicity following the combination regimen. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=idebenone" title="idebenone">idebenone</a>, <a href="https://publications.waset.org/abstracts/search?q=carnosine" title=" carnosine"> carnosine</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20E" title=" vitamin E"> vitamin E</a>, <a href="https://publications.waset.org/abstracts/search?q=TiO2%20NPS" title=" TiO2 NPS"> TiO2 NPS</a>, <a href="https://publications.waset.org/abstracts/search?q=caspase-3" title=" caspase-3"> caspase-3</a>, <a href="https://publications.waset.org/abstracts/search?q=NrF2" title=" NrF2"> NrF2</a>, <a href="https://publications.waset.org/abstracts/search?q=NF-KB" title=" NF-KB"> NF-KB</a> </p> <a href="https://publications.waset.org/abstracts/7223/amelioration-of-over-expression-of-bax-nrf2-and-nfk-v-in-nano-sized-titanium-dioxide-intoxicated-mice-by-potent-antioxidants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7223.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elham%20Sharif">Elham Sharif</a>, <a href="https://publications.waset.org/abstracts/search?q=Nasser%20Rizk"> Nasser Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=Sirin%20Abu%20Aqel"> Sirin Abu Aqel</a>, <a href="https://publications.waset.org/abstracts/search?q=Ofelia%20Masoud"> Ofelia Masoud</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms in vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ethnic backgrounds. Aim: The aim of this study is to investigate the association between VDR polymorphisms using three SNP’s (rs1544410, rs7975232 and rs731236) and the severity of the significant lesion in coronary arteries among angiographically diagnosed CAD. Methods: A prospective-retrospective study was conducted on 192 CAD patients enrolled from the cardiology department-Heart Hospital HMC, grouped in 96 subjects with significant stenosis and 96 with non-significant stenosis with a mean age between 30 and 75 years old. Genotyping was performed for the following SNPs rs1544410, rs7975232 and rs731236 using TaqMan assay by the Real Time PCR, ABI 7500 in Health Sciences Labs at Qatar University Biomedical Research Center. Results: The results showed that both groups have matched age and gender distribution but patients with the significant stenosis have significantly higher; BMI (p=0.047); smoking status (p=0.039); FBS (p= 0.031); CK-MB (p=0.025) and Troponin (p=0.002) than the patients with non–significant lesion. Among the traditional risk factors, smoking increases the odds of the severe stenotic lesion in CAD patients by 1.984, with 95% CI between 1.024 – 7.063, with p= 0.042.HWE showed deviations of the rs1544410 and rs731236 among the study subjects. The most frequent genotype in distribution of rs7975232 is the AA among the significant stenosis patients, while the heterozygous AC was the frequent genotype in distribution among the non-significant stenosis group. The carriers of CC genotype in rs7975232 increased the risk of having significant coronary arteries stenotic lesion by 1.83 with 95% CI (1.020 – 3.280), p=0.043. No association was found between the rs7975232 with vitamin D and VDBP. Conclusion: There is a significant association between rs7975232 and the severity of CAD lesion. The carrier of CC genotype in rs7975232 increased the risk of having significant coronary arteries atherosclerotic lesion especially in patients with smoking history independent of vitamin D. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D" title="vitamin D">vitamin D</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D%20receptor" title=" vitamin D receptor"> vitamin D receptor</a>, <a href="https://publications.waset.org/abstracts/search?q=polymorphism" title=" polymorphism"> polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20harat%20disease" title=" coronary harat disease"> coronary harat disease</a> </p> <a href="https://publications.waset.org/abstracts/48048/associations-of-vitamin-d-receptor-polymorphisms-with-coronary-artery-diseases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48048.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">312</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> New Insights Into Gluten-Free Bread Staling Treatment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sayed%20Mostafa">Sayed Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Siham%20Mostafa%20Mohamed%20Faheid"> Siham Mostafa Mohamed Faheid</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20Rizk%20Sayed%20Ahmed"> Ibrahim Rizk Sayed Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Yasser%20Fehry%20Mohamed%20Kishk"> Yasser Fehry Mohamed Kishk</a>, <a href="https://publications.waset.org/abstracts/search?q=Gamal%20Hassan%20Ragab"> Gamal Hassan Ragab</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Gluten-free foods are still the only treatment for gluten-allergic patients. Consequently, this study is concerned with improving the quality attributes of gluten-free bread using different concentrations (0, 20, 40, 60 and 80ppm) of all maltogenic α-amylase (MA) and xylanase (XY) compared with wheat flour Balady bread and untreated gluten-free Balady bread (GFBB). Pasting properties, falling number, water activity, alkaline water retention capacity (AWRC) and sensory properties (fresh bread, after 24h, after 48h and after 72h) of gluten-free bread were evaluated. Additionally, the effect of merging different concentrations of maltogenic α-amylase and xylanase on stalling behavior (AWRC) and sensory properties of gluten-free Balady bread was investigated. The addition of MA led to a gradually decreased peak viscosity, breakdown, setback and pasting temperature of GFBB with the increasing level of MA. Maltogenic α-amylase and xylanase addition led to a reduction in the FN values compared to the untreated gluten-free sample, noting that the MA-treated samples showed a significant decrease compared to the XY-treated and untreated samples. Wheat flour Balady bread significantly showed a higher value of AWRC compared to untreated gluten-free Balady bread at different storage periods (zero time, after 24h, after 48h and after 72h). MA-treated samples showed higher water binding capacity and water activity (aw)in comparison with XY-treated samples, with significance during all storage periods. Concerning the overall acceptability during the third day, the highest score (4.6) was observed by the GFBB sample containing 40ppm MA, followed by 4.3, which was investigated by the GFBB sample containing 80ppm XY with no significance between them and with significance compared to the other samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=celiac%20disease" title="celiac disease">celiac disease</a>, <a href="https://publications.waset.org/abstracts/search?q=gluten-free%20products" title=" gluten-free products"> gluten-free products</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-stalling%20agents" title=" anti-stalling agents"> anti-stalling agents</a>, <a href="https://publications.waset.org/abstracts/search?q=maltogenic%20%CE%B1-amylase" title=" maltogenic α-amylase"> maltogenic α-amylase</a>, <a href="https://publications.waset.org/abstracts/search?q=xylanase" title=" xylanase"> xylanase</a> </p> <a href="https://publications.waset.org/abstracts/173389/new-insights-into-gluten-free-bread-staling-treatment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173389.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">84</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Down Regulation of Smad-2 Transcription and TGF-B1 Signaling in Nano Sized Titanium Dioxide-Induced Liver Injury in Mice by Potent Antioxidants</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maha%20Z.%20Rizk">Maha Z. Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=Sami%20A.%20Fattah"> Sami A. Fattah</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20M.%20Darwish"> Heba M. Darwish</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanaa%20A.%20Ali"> Sanaa A. Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Mai%20O.%20Kadry"> Mai O. Kadry</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Although it is known that nano-TiO2 and other nanoparticles can induce liver toxicity, the mechanisms and the molecular pathogenesis are still unclear. The present study investigated some biochemical indices of nano-sized Titanium dioxide (TiO2 NPS) toxicity in mice liver and the ameliorative efficacy of individual and combined doses of idebenone, carnosine and vitamin E. Nano-anatase TiO2 (21 nm) was administered as a total oral dose of 2.2 gm/Kg daily for 2 weeks followed by the afore-mentioned antioxidants daily either individually or in combination for 1month. TiO2-NPS induced a significant elevation in serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and hepatic oxidative stress biomarkers [lipid peroxides (LP), and nitric oxide levels (NOX), while it significantly reduced glutathione reductase (GR), reduced glutathione (GSH) and glutathione peroxidase(GPX) levels. Moreover the quantitative RT-PCR analysis showed that nano-anatase TiO2 can significantly alter the mRNA and protein expressions of the fibrotic factors TGF-B1, VEGFand Smad-2. Histopathological examination of hepatic tissue reinforced the previous biochemical results. Our results also implied that inflammatory responses and liver injury may be involved in nano-anatase TiO2-induced liver toxicity Tumor necrosis factor-α (TNF-α) and Interleukin -6 (IL-6) and increased the percent of DNA damage which was assessed by COMET assay in addition to the apoptotic marker Caspase-3. Moreover mRNA gene expression observed by RT-PCR showed a significant overexpression in nuclear factor relation -2 (Nrf2), nuclear factor kappa beta (NF-Kβ) and the apoptotic factor (bax), and a significant down regulation in the antiapoptotic factor (bcl2) level. In conclusion idebenone, carnosine and vitamin E ameliorated the deviated previously mentioned parameters with variable degrees with the most pronounced role in alleviating the hazardous effect of TiO2 NPS toxicity following the combination regimen. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nano-anatase%20TiO2" title="Nano-anatase TiO2">Nano-anatase TiO2</a>, <a href="https://publications.waset.org/abstracts/search?q=TGF-B1" title=" TGF-B1"> TGF-B1</a>, <a href="https://publications.waset.org/abstracts/search?q=SMAD-2" title=" SMAD-2"> SMAD-2</a> </p> <a href="https://publications.waset.org/abstracts/7222/down-regulation-of-smad-2-transcription-and-tgf-b1-signaling-in-nano-sized-titanium-dioxide-induced-liver-injury-in-mice-by-potent-antioxidants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7222.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">424</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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