Antibiotic Research and Development - Public vs. Private Funding

<!DOCTYPE html> <html lang="en"> <head> <meta charset="UTF-8"> <title> Antibiotic Research and Development - Public vs. Private Funding </title> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link rel="canonical" href="https://www.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/" />  <script async src="https://www.googletagmanager.com/gtag/js?id=G-YK7FCK71TD"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-YK7FCK71TD'); </script> <meta name="description" content="" /> <meta name="keywords" content="" />  <meta name="twitter:card" content="summary_large_image"> <meta name="twitter:title" content="Antibiotic Research and Development - Public vs. Private Funding"> <meta name="twitter:description" content=""> <meta name="twitter:image" content="https://www.biopharmatrend.com/files/blog/social/blog/20190721_142236.7811_2.png">  <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/" /> <meta property="og:title" content="Antibiotic Research and Development - Public vs. Private Funding" /> <meta property="og:description" content="" /> <meta property="article:published_time" content="2019-05-27T16:53:19+00:00"> <meta property="article:modified_time" content="2019-05-27T16:53:19+00:00"> <meta name="author" content="David Shlaes"> <meta property="og:image" content="https://www.biopharmatrend.com/files/blog/social/blog/20190721_142236.7811_2.png"> <script type="application/ld+json">{ "@context": "https://schema.org", "@type": "Article", "headline": "Antibiotic Research and Development - Public vs. Private Funding", "datePublished": "2019-05-27T16:53:19+00:00", "dateModified": "2019-05-27T16:53:19+00:00", "description": "Over the past decade, pull incentives as a solution to the broken antibiotic market have been proposed to entice companies into antibiotic research and development.\u00a0\u00a0These incentives would essentially provide a market, and therefore a return on investment for pharmaceutical companies.\u00a0Almost all of today\u2019s inadequate antibiotic pipeline is provided by biotech and small pharma.\u00a0\u00a0All are threatened with loss of investor interest because of the failed marketplace and many are experiencing difficulty in raising funds either from public or private markets.\u00a0\u00a0One alternative to providing money to the \u201cevil\u201d pharmaceutical industry via a substantial pull incentive is to create publicly funded non-profit organizations or public-private ventures that would essentially replace the industry in antibiotic research, development and commercialization. Two proponents of this approach are Lord\nJim O\u2019Neill\n(of the O\u2019Neill Commission or Antimicrobial Resistance Review fame) and\nRamanan Laxminarayan\nof the Center for Disease Dynamics, Economics and Policy and of GARDP. Both, clearly, are key thought leaders in the area.", "image": "https://www.biopharmatrend.com/files/blog/social/blog/20190721_142236.7811_2.png", "url": "https://www.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/", "mainEntityOfPage": { "@type": "WebPage", "@id": "https://www.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/" }, "publisher": { "@type": "Organization", "name": "BiopharmaTrend", "url": "https://www.biopharmatrend.com", "logo": { "@type": "ImageObject", "url": "https://www.biopharmatrend.com/static/img/bpt_logo.png" } }, "author": [ { "@type": "Person", "name": "David Shlaes", "url": "https://www.biopharmatrend.com/contributor/29/" } ] }</script> <style type="text/css"> .ap-chart-load svg { width: 100%; } .post-meta .author-linkein-icon { width: 1em; vertical-align: baseline; } .text-miniblock { display: inline-block; box-shadow: 0 0 6px -1px forestgreen; background: white; padding: 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src="/static/img/linkedin_icon_50x50.71dcf83d1029.png" class="author-linkein-icon" /> </a> <span class="tooltip-trigger" onclick="this.parentElement.classList.toggle('tooltip-show')"> Contributor <i class="glyphicon glyphicon-info-sign"></i></span>    <span style="white-space: nowrap;"> <span class="glyphicon glyphicon-folder-open"></span>   Biopharma insight / Biopharma Insights </span> <div class="tooltip-text"> <div class="tooltip-close" onclick="this.parentElement.parentElement.classList.toggle('tooltip-show');"></div> <p><b>Disclaimer</b>: All opinions expressed by Contributors are their own and do not represent those of their employers, or BiopharmaTrend.com. <br> Contributors are fully responsible for assuring they own any required copyright for any content they submit to BiopharmaTrend.com. This website and its owners shall not be liable for neither information and content submitted for publication by Contributors, nor its accuracy.</p> </div> </div> <div> <span class="glyphicon glyphicon-calendar" title="Published on"></span> <time datetime="2019-05-27">May 27, 2019</time>    </em> </div> <div class="tags"> <b>Topics: </b> <a href="/topic/novel-therapeutics/">Novel Therapeutics</a>    </div> <div> <strong>Share: </strong>   <a target="_blank" rel="nofollow" href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in LinkedIn" src="/static/img/soc-in.7bc286fd757e.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://www.reddit.com/submit?url=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in Reddit" src="/static/img/soc-reddit.342e87a07115.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in X" src="/static/img/soc-x.3c80e8291cba.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://news.ycombinator.com/submitlink?u=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in Hacker News" src="/static/img/soc-y.587f16a5f3f3.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/&display=page"> <img alt="Share in Facebook" src="/static/img/soc-fb.3031a5a810f0.png" width="28" height="28" /></a>  <a target="_blank" rel="nofollow" href="mailto:?subject=Biopharmatrend.com&body=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Send by email" src="/static/img/soc-mail.41ce3608f438.png" width="28" height="28"></a> </div> </footer> <section> <p>Over the past decade, pull incentives as a solution to the broken antibiotic market have been proposed to entice companies into antibiotic research and development.  These incentives would essentially provide a market, and therefore a return on investment for pharmaceutical companies. Almost all of today’s inadequate antibiotic pipeline is provided by biotech and small pharma.  All are threatened with loss of investor interest because of the failed marketplace and many are experiencing difficulty in raising funds either from public or private markets.  One alternative to providing money to the “evil” pharmaceutical industry via a substantial pull incentive is to create publicly funded non-profit organizations or public-private ventures that would essentially replace the industry in antibiotic research, development and commercialization. Two proponents of this approach are Lord <a href="https://revive.gardp.org/more-than-one-model-to-stimulate-antimicrobial-drug-development/">Jim O’Neill</a> (of the O’Neill Commission or Antimicrobial Resistance Review fame) and <a href="https://sciencespeaksblog.org/2019/05/22/world-health-assembly-2019-as-antibiotic-pipeline-dimishes-time-runs-out-for-patients/">Ramanan Laxminarayan</a> of the Center for Disease Dynamics, Economics and Policy and of GARDP. Both, clearly, are key thought leaders in the area. </p> <div style="overflow: hidden;"><div>The proposal sounds great. Who wants to give the pharmaceutical industry money, after all? But I find myself scratching my head about this. How, precisely, would this work? I presume we’re talking about government funding for an antibiotic R&D organization. In the US, would this be the National Institute for Allergy and Infectious Disease? They have a strong track record in vaccine and in antiviral research – but antibiotics – not so much. Commercialization of products - not at all. In the UK would this be the Medical Research Council? In Europe would it be the European Commission? None of these august bodies have the experience required to establish a successful antibiotic R&D organization (in my humble view). The <a href="https://www.imi.europa.eu/">Innovate Medicines Initiative</a>, an EU-funded public-private venture, has had mixed success tackling small pieces of antibiotic R&D but has not delivered a product to market and was not designed for that purpose. Then are we talking about establishing an independent organization with government funding? Who would decide who would lead the group? (On the positive side, there are lots of available antibiotic researchers available for hire.) To whom would the organization be accountable?</div><div> </div><div>In addition to the questions posed above, we should all recognize the precedent this approach could set. Just think. We could solve the entire pharmaceutical pricing problem with publicly funded R&D efforts – not just for antibiotics, but for all therapeutic areas. We could eliminate the evil pharmaceutical industry altogether. Do we want to go there?</div></div> <div class="access-premium text-center"> <h3>Continue reading</h3> <p><big>This content available exclusively for BPT Mebmers</big></p> <div><a href="/membership/?success_page=/post/96-antibiotic-research-and-development-public-vs-private-funding/" class="btn btn-bpt-white"> BPT Membership </a></div> <div><button type="button" onclick="document.getElementById('login-popup').classList.toggle('hidden')" class="btn btn-link" style="color:white; vertical-align: middle;"> Sign in </button></div> </div> <p> <b>Topics: </b> <a href="/topic/novel-therapeutics/">Novel Therapeutics</a>    </p> </section> </article> <div style="margin: 1em 0 2em; padding: 0.5em 0;"> <strong>Share: </strong>   <a target="_blank" rel="nofollow" href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in LinkedIn" src="/static/img/soc-in.7bc286fd757e.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://www.reddit.com/submit?url=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in Reddit" src="/static/img/soc-reddit.342e87a07115.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in X" src="/static/img/soc-x.3c80e8291cba.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://news.ycombinator.com/submitlink?u=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Share in Hacker News" src="/static/img/soc-y.587f16a5f3f3.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/&display=page"> <img alt="Share in Facebook" src="/static/img/soc-fb.3031a5a810f0.png" width="28" height="28" /></a>  <a target="_blank" rel="nofollow" href="mailto:?subject=Biopharmatrend.com&body=https%3A%2F%2Fwww.biopharmatrend.com/post/96-antibiotic-research-and-development-public-vs-private-funding/"> <img alt="Send by email" src="/static/img/soc-mail.41ce3608f438.png" width="28" height="28"></a> </div> <div class="subscribe-block"> <div class="subscribe-inner"> <h3 style="line-height:1.5; 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Antibiotic Research and Development - Public vs. Private Funding